id category name description provided_by synonym http://pharos.nih.govdrug_targets biolink:directly_physically_interacts_with Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_approved_unknown_phase biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_0 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_1 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_1_or_phase_2 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_2 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_2_or_phase_3 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_suspended_phase_3 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_0 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_1 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_1_or_phase_2 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_2 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_2_or_phase_3 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_terminated_phase_3 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_0 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_1 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_1_or_phase_2 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_2 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_2_or_phase_3 biolink:treats Graph http://apps.chiragjpgroup.org/repoDB/clinically_tested_withdrawn_phase_3 biolink:treats Graph http://bio2rdf.org/wormbase_vocabularyGene-GO-Association biolink:GeneToGoTermAssociation Graph http://bio2rdf.org/wormbase_vocabularyGene-Phenotype-Association biolink:GeneToPhenotypicFeatureAssociation Graph http://ctdbase.org/affects_binding biolink:directly_physically_interacts_with Graph http://ctdbase.org/affects_response_to biolink:affects_response_to Graph http://ctdbase.org/decreases_response_to biolink:decreases_response_to Graph http://ctdbase.org/decreases_response_to_substance biolink:decreases_response_to Graph http://ctdbase.org/increases_response_to biolink:increases_response_to Graph http://ctdbase.org/inferred biolink:affects Graph http://ctdbase.org/marker_mechanism biolink:contributes_to Graph http://ctdbase.org/negative_correlation biolink:negatively_correlated_with Graph http://ctdbase.org/positive_correlation biolink:positively_correlated_with Graph http://ctdbase.org/prediction_hypothesis biolink:affects Graph http://drugcentral.org/drugcard/5271 biolink:diagnoses Graph FlyBase:FBgn0000137 biolink:NamedThing Graph FlyBase:FBgn0000157 biolink:NamedThing Graph FlyBase:FBgn0000158 biolink:NamedThing Graph FlyBase:FBgn0000179 biolink:NamedThing Graph FlyBase:FBgn0000395 biolink:NamedThing Graph FlyBase:FBgn0000463 biolink:NamedThing Graph FlyBase:FBgn0000490 biolink:NamedThing Graph FlyBase:FBgn0000500 biolink:NamedThing Graph FlyBase:FBgn0000504 biolink:NamedThing Graph FlyBase:FBgn0000546 biolink:NamedThing Graph FlyBase:FBgn0000564 biolink:NamedThing Graph FlyBase:FBgn0000577 biolink:NamedThing Graph FlyBase:FBgn0000606 biolink:NamedThing Graph FlyBase:FBgn0000636 biolink:NamedThing Graph FlyBase:FBgn0000964 biolink:NamedThing Graph FlyBase:FBgn0001235 biolink:NamedThing Graph FlyBase:FBgn0001257 biolink:NamedThing Graph FlyBase:FBgn0001981 biolink:NamedThing Graph FlyBase:FBgn0002522 biolink:NamedThing Graph FlyBase:FBgn0002565 biolink:NamedThing Graph FlyBase:FBgn0002576 biolink:NamedThing Graph FlyBase:FBgn0002673 biolink:NamedThing Graph FlyBase:FBgn0002985 biolink:NamedThing Graph FlyBase:FBgn0003068 biolink:NamedThing Graph FlyBase:FBgn0003249 biolink:NamedThing Graph FlyBase:FBgn0003250 biolink:NamedThing Graph FlyBase:FBgn0003255 biolink:NamedThing Graph FlyBase:FBgn0003463 biolink:NamedThing Graph FlyBase:FBgn0003507 biolink:NamedThing Graph FlyBase:FBgn0003651 biolink:NamedThing Graph FlyBase:FBgn0003747 biolink:NamedThing Graph FlyBase:FBgn0003866 biolink:NamedThing Graph FlyBase:FBgn0003961 biolink:NamedThing Graph FlyBase:FBgn0003975 biolink:NamedThing Graph FlyBase:FBgn0004102 biolink:NamedThing Graph FlyBase:FBgn0004198 biolink:NamedThing Graph FlyBase:FBgn0004228 biolink:NamedThing Graph FlyBase:FBgn0004552 biolink:NamedThing Graph FlyBase:FBgn0004595 biolink:NamedThing Graph FlyBase:FBgn0004606 biolink:NamedThing Graph FlyBase:FBgn0004618 biolink:NamedThing Graph FlyBase:FBgn0004644 biolink:NamedThing Graph FlyBase:FBgn0004652 biolink:NamedThing Graph FlyBase:FBgn0004666 biolink:NamedThing Graph FlyBase:FBgn0004956 biolink:NamedThing Graph FlyBase:FBgn0005638 biolink:NamedThing Graph FlyBase:FBgn0005677 biolink:NamedThing Graph FlyBase:FBgn0005775 biolink:NamedThing Graph FlyBase:FBgn0010109 biolink:NamedThing Graph FlyBase:FBgn0010226 biolink:NamedThing Graph FlyBase:FBgn0010397 biolink:NamedThing Graph FlyBase:FBgn0010433 biolink:NamedThing Graph FlyBase:FBgn0010453 biolink:NamedThing Graph FlyBase:FBgn0011581 biolink:NamedThing Graph FlyBase:FBgn0011701 biolink:NamedThing Graph FlyBase:FBgn0011723 biolink:NamedThing Graph FlyBase:FBgn0012344 biolink:NamedThing Graph FlyBase:FBgn0013323 biolink:NamedThing Graph FlyBase:FBgn0013469 biolink:NamedThing Graph FlyBase:FBgn0013767 biolink:NamedThing Graph FlyBase:FBgn0014019 biolink:NamedThing Graph FlyBase:FBgn0014163 biolink:NamedThing Graph FlyBase:FBgn0014179 biolink:NamedThing Graph FlyBase:FBgn0014343 biolink:NamedThing Graph FlyBase:FBgn0014396 biolink:NamedThing Graph FlyBase:FBgn0015380 biolink:NamedThing Graph FlyBase:FBgn0015591 biolink:NamedThing Graph FlyBase:FBgn0019940 biolink:NamedThing Graph FlyBase:FBgn0020258 biolink:NamedThing Graph FlyBase:FBgn0020299 biolink:NamedThing Graph FlyBase:FBgn0020386 biolink:NamedThing Graph FlyBase:FBgn0023091 biolink:NamedThing Graph FlyBase:FBgn0023178 biolink:NamedThing Graph FlyBase:FBgn0023523 biolink:NamedThing Graph FlyBase:FBgn0025360 biolink:NamedThing Graph FlyBase:FBgn0025525 biolink:NamedThing Graph FlyBase:FBgn0025595 biolink:NamedThing Graph FlyBase:FBgn0025680 biolink:NamedThing Graph FlyBase:FBgn0025697 biolink:NamedThing Graph FlyBase:FBgn0025739 biolink:NamedThing Graph FlyBase:FBgn0026384 biolink:NamedThing Graph FlyBase:FBgn0026385 biolink:NamedThing Graph FlyBase:FBgn0026386 biolink:NamedThing Graph FlyBase:FBgn0026388 biolink:NamedThing Graph FlyBase:FBgn0026389 biolink:NamedThing Graph FlyBase:FBgn0026390 biolink:NamedThing Graph FlyBase:FBgn0026391 biolink:NamedThing Graph FlyBase:FBgn0026392 biolink:NamedThing Graph FlyBase:FBgn0026393 biolink:NamedThing Graph FlyBase:FBgn0026394 biolink:NamedThing Graph FlyBase:FBgn0026395 biolink:NamedThing Graph FlyBase:FBgn0026396 biolink:NamedThing Graph FlyBase:FBgn0026397 biolink:NamedThing Graph FlyBase:FBgn0026398 biolink:NamedThing Graph FlyBase:FBgn0026399 biolink:NamedThing Graph FlyBase:FBgn0027109 biolink:NamedThing Graph FlyBase:FBgn0027343 biolink:NamedThing Graph FlyBase:FBgn0027945 biolink:NamedThing Graph FlyBase:FBgn0028374 biolink:NamedThing Graph FlyBase:FBgn0028418 biolink:NamedThing Graph FlyBase:FBgn0028430 biolink:NamedThing Graph FlyBase:FBgn0028841 biolink:NamedThing Graph FlyBase:FBgn0028946 biolink:NamedThing Graph FlyBase:FBgn0028963 biolink:NamedThing Graph FlyBase:FBgn0029521 biolink:NamedThing Graph FlyBase:FBgn0029768 biolink:NamedThing Graph FlyBase:FBgn0030016 biolink:NamedThing Graph FlyBase:FBgn0030204 biolink:NamedThing Graph FlyBase:FBgn0030298 biolink:NamedThing Graph FlyBase:FBgn0030608 biolink:NamedThing Graph FlyBase:FBgn0030715 biolink:NamedThing Graph FlyBase:FBgn0030795 biolink:NamedThing Graph FlyBase:FBgn0030844 biolink:NamedThing Graph FlyBase:FBgn0030900 biolink:NamedThing Graph FlyBase:FBgn0031209 biolink:NamedThing Graph FlyBase:FBgn0031903 biolink:NamedThing Graph FlyBase:FBgn0032048 biolink:NamedThing Graph FlyBase:FBgn0032096 biolink:NamedThing Graph FlyBase:FBgn0032336 biolink:NamedThing Graph FlyBase:FBgn0032422 biolink:NamedThing Graph FlyBase:FBgn0032840 biolink:NamedThing Graph FlyBase:FBgn0033041 biolink:NamedThing Graph FlyBase:FBgn0033043 biolink:NamedThing Graph FlyBase:FBgn0033259 biolink:NamedThing Graph FlyBase:FBgn0033327 biolink:NamedThing Graph FlyBase:FBgn0033367 biolink:NamedThing Graph FlyBase:FBgn0033404 biolink:NamedThing Graph FlyBase:FBgn0033422 biolink:NamedThing Graph FlyBase:FBgn0033725 biolink:NamedThing Graph FlyBase:FBgn0033727 biolink:NamedThing Graph FlyBase:FBgn0033744 biolink:NamedThing Graph FlyBase:FBgn0034458 biolink:NamedThing Graph FlyBase:FBgn0034473 biolink:NamedThing Graph FlyBase:FBgn0034865 biolink:NamedThing Graph FlyBase:FBgn0034866 biolink:NamedThing Graph FlyBase:FBgn0034935 biolink:NamedThing Graph FlyBase:FBgn0035023 biolink:NamedThing Graph FlyBase:FBgn0035092 biolink:NamedThing Graph FlyBase:FBgn0035282 biolink:NamedThing Graph FlyBase:FBgn0035382 biolink:NamedThing Graph FlyBase:FBgn0035468 biolink:NamedThing Graph FlyBase:FBgn0035486 biolink:NamedThing Graph FlyBase:FBgn0035604 biolink:NamedThing Graph FlyBase:FBgn0035610 biolink:NamedThing Graph FlyBase:FBgn0035870 biolink:NamedThing Graph FlyBase:FBgn0035934 biolink:NamedThing Graph FlyBase:FBgn0036009 biolink:NamedThing Graph FlyBase:FBgn0036019 biolink:NamedThing Graph FlyBase:FBgn0036046 biolink:NamedThing Graph FlyBase:FBgn0036078 biolink:NamedThing Graph FlyBase:FBgn0036080 biolink:NamedThing Graph FlyBase:FBgn0036150 biolink:NamedThing Graph FlyBase:FBgn0036260 biolink:NamedThing Graph FlyBase:FBgn0036414 biolink:NamedThing Graph FlyBase:FBgn0036474 biolink:NamedThing Graph FlyBase:FBgn0036709 biolink:NamedThing Graph FlyBase:FBgn0036713 biolink:NamedThing Graph FlyBase:FBgn0036757 biolink:NamedThing Graph FlyBase:FBgn0036829 biolink:NamedThing Graph FlyBase:FBgn0037322 biolink:NamedThing Graph FlyBase:FBgn0037399 biolink:NamedThing Graph FlyBase:FBgn0037501 biolink:NamedThing Graph FlyBase:FBgn0037576 biolink:NamedThing Graph FlyBase:FBgn0037590 biolink:NamedThing Graph FlyBase:FBgn0037591 biolink:NamedThing Graph FlyBase:FBgn0037594 biolink:NamedThing Graph FlyBase:FBgn0037672 biolink:NamedThing Graph FlyBase:FBgn0037685 biolink:NamedThing Graph FlyBase:FBgn0037976 biolink:NamedThing Graph FlyBase:FBgn0038147 biolink:NamedThing Graph FlyBase:FBgn0038199 biolink:NamedThing Graph FlyBase:FBgn0038203 biolink:NamedThing Graph FlyBase:FBgn0038309 biolink:NamedThing Graph FlyBase:FBgn0038343 biolink:NamedThing Graph FlyBase:FBgn0038402 biolink:NamedThing Graph FlyBase:FBgn0038789 biolink:NamedThing Graph FlyBase:FBgn0038798 biolink:NamedThing Graph FlyBase:FBgn0038901 biolink:NamedThing Graph FlyBase:FBgn0039007 biolink:NamedThing Graph FlyBase:FBgn0039033 biolink:NamedThing Graph FlyBase:FBgn0039034 biolink:NamedThing Graph FlyBase:FBgn0039080 biolink:NamedThing Graph FlyBase:FBgn0039551 biolink:NamedThing Graph FlyBase:FBgn0039582 biolink:NamedThing Graph FlyBase:FBgn0039722 biolink:NamedThing Graph FlyBase:FBgn0040849 biolink:NamedThing Graph FlyBase:FBgn0041229 biolink:NamedThing Graph FlyBase:FBgn0041231 biolink:NamedThing Graph FlyBase:FBgn0041243 biolink:NamedThing Graph FlyBase:FBgn0041247 biolink:NamedThing Graph FlyBase:FBgn0041250 biolink:NamedThing Graph FlyBase:FBgn0041621 biolink:NamedThing Graph FlyBase:FBgn0041622 biolink:NamedThing Graph FlyBase:FBgn0041623 biolink:NamedThing Graph FlyBase:FBgn0041624 biolink:NamedThing Graph FlyBase:FBgn0041625 biolink:NamedThing Graph FlyBase:FBgn0041626 biolink:NamedThing Graph FlyBase:FBgn0043005 biolink:NamedThing Graph FlyBase:FBgn0043576 biolink:NamedThing Graph FlyBase:FBgn0044046 biolink:NamedThing Graph FlyBase:FBgn0045476 biolink:NamedThing Graph FlyBase:FBgn0045477 biolink:NamedThing Graph FlyBase:FBgn0045479 biolink:NamedThing Graph FlyBase:FBgn0045495 biolink:NamedThing Graph FlyBase:FBgn0045498 biolink:NamedThing Graph FlyBase:FBgn0050263 biolink:NamedThing Graph FlyBase:FBgn0051718 biolink:NamedThing Graph FlyBase:FBgn0051956 biolink:NamedThing Graph FlyBase:FBgn0052255 biolink:NamedThing Graph FlyBase:FBgn0052693 biolink:NamedThing Graph FlyBase:FBgn0053349 biolink:NamedThing Graph FlyBase:FBgn0053527 biolink:NamedThing Graph FlyBase:FBgn0062565 biolink:NamedThing Graph FlyBase:FBgn0085417 biolink:NamedThing Graph FlyBase:FBgn0085424 biolink:NamedThing Graph FlyBase:FBgn0086347 biolink:NamedThing Graph FlyBase:FBgn0086782 biolink:NamedThing Graph FlyBase:FBgn0087002 biolink:NamedThing Graph FlyBase:FBgn0259185 biolink:NamedThing Graph FlyBase:FBgn0259194 biolink:NamedThing Graph FlyBase:FBgn0259683 biolink:NamedThing Graph FlyBase:FBgn0259896 biolink:NamedThing Graph FlyBase:FBgn0260400 biolink:NamedThing Graph FlyBase:FBgn0260874 biolink:NamedThing Graph FlyBase:FBgn0260942 biolink:NamedThing Graph FlyBase:FBgn0261401 biolink:NamedThing Graph FlyBase:FBgn0261402 biolink:NamedThing Graph FlyBase:FBgn0263776 biolink:NamedThing Graph FlyBase:FBgn0264953 biolink:NamedThing Graph FlyBase:FBgn0265139 biolink:NamedThing Graph FlyBase:FBgn0266429 biolink:NamedThing Graph FlyBase:FBgn0267796 biolink:NamedThing Graph FlyBase:FBgn0283437 biolink:NamedThing Graph FlyBase:FBgn0283442 biolink:NamedThing Graph FlyBase:FBgn0283499 biolink:NamedThing Graph FlyBase:FBgn0284084 biolink:NamedThing Graph FlyBase:FBgn0285963 biolink:NamedThing Graph http://gmod.org/wiki/Chado/feature_relationship biolink:SequenceFeatureRelationship Graph http://id.nlm.nih.gov/mesh/D002477 biolink:Cell Graph http://id.nlm.nih.gov/mesh/D010641 biolink:PhenotypicFeature Graph http://id.nlm.nih.gov/mesh/RO biolink:related_to Graph http://id.nlm.nih.gov/mesh/has_mapping_qualifier biolink:related_to Graph http://id.nlm.nih.gov/mesh/inverse_isa biolink:superclass_of Graph http://id.nlm.nih.gov/mesh/isa biolink:subclass_of Graph http://id.nlm.nih.gov/mesh/mapped_to biolink:related_to Graph HGNC:10006 biolink:NamedThing Graph HGNC:10012 biolink:NamedThing Graph HGNC:10013 biolink:NamedThing Graph HGNC:10023 biolink:NamedThing Graph HGNC:10024 biolink:NamedThing Graph HGNC:10031 biolink:NamedThing Graph HGNC:10050 biolink:NamedThing Graph HGNC:10057 biolink:NamedThing Graph HGNC:1012 biolink:NamedThing Graph HGNC:1014 biolink:NamedThing Graph HGNC:1020 biolink:NamedThing Graph HGNC:10250 biolink:NamedThing Graph HGNC:10254 biolink:NamedThing Graph HGNC:10257 biolink:NamedThing Graph HGNC:10260 biolink:NamedThing Graph HGNC:10263 biolink:NamedThing Graph HGNC:10274 biolink:NamedThing Graph HGNC:10288 biolink:NamedThing Graph HGNC:10294 biolink:NamedThing Graph HGNC:10295 biolink:NamedThing Graph HGNC:10297 biolink:NamedThing Graph HGNC:10298 biolink:NamedThing Graph HGNC:103 biolink:NamedThing Graph HGNC:10301 biolink:NamedThing Graph HGNC:10306 biolink:NamedThing Graph HGNC:10313 biolink:NamedThing Graph HGNC:10327 biolink:NamedThing Graph HGNC:1033 biolink:NamedThing Graph HGNC:10345 biolink:NamedThing Graph HGNC:10360 biolink:NamedThing Graph HGNC:1037 biolink:NamedThing Graph HGNC:10379 biolink:NamedThing Graph HGNC:10383 biolink:NamedThing Graph HGNC:10387 biolink:NamedThing Graph HGNC:10397 biolink:NamedThing Graph HGNC:1040 biolink:NamedThing Graph HGNC:10402 biolink:NamedThing Graph HGNC:1041 biolink:NamedThing Graph HGNC:10411 biolink:NamedThing Graph HGNC:10414 biolink:NamedThing Graph HGNC:10418 biolink:NamedThing Graph HGNC:10419 biolink:NamedThing Graph HGNC:10432 biolink:NamedThing Graph HGNC:1044 biolink:NamedThing Graph HGNC:10440 biolink:NamedThing Graph HGNC:10457 biolink:NamedThing Graph HGNC:10468 biolink:NamedThing Graph HGNC:10471 biolink:NamedThing Graph HGNC:10472 biolink:NamedThing Graph HGNC:10483 biolink:NamedThing Graph HGNC:10484 biolink:NamedThing Graph HGNC:105 biolink:NamedThing Graph HGNC:10519 biolink:NamedThing Graph HGNC:1052 biolink:NamedThing Graph HGNC:10521 biolink:NamedThing Graph HGNC:10524 biolink:NamedThing Graph HGNC:10526 biolink:NamedThing Graph HGNC:10535 biolink:NamedThing Graph HGNC:10536 biolink:NamedThing Graph HGNC:10542 biolink:NamedThing Graph HGNC:10545 biolink:NamedThing Graph HGNC:10547 biolink:NamedThing Graph HGNC:10548 biolink:NamedThing Graph HGNC:10549 biolink:NamedThing Graph HGNC:10555 biolink:NamedThing Graph HGNC:10560 biolink:NamedThing Graph HGNC:1057 biolink:NamedThing Graph HGNC:1058 biolink:NamedThing Graph HGNC:10582 biolink:NamedThing Graph HGNC:10583 biolink:NamedThing Graph HGNC:10585 biolink:NamedThing Graph HGNC:10586 biolink:NamedThing Graph HGNC:10588 biolink:NamedThing Graph HGNC:10589 biolink:NamedThing Graph HGNC:10591 biolink:NamedThing Graph HGNC:10592 biolink:NamedThing Graph HGNC:10593 biolink:NamedThing Graph HGNC:10596 biolink:NamedThing Graph HGNC:10597 biolink:NamedThing Graph HGNC:10599 biolink:NamedThing Graph HGNC:10600 biolink:NamedThing Graph HGNC:10602 biolink:NamedThing Graph HGNC:10604 biolink:NamedThing Graph HGNC:10606 biolink:NamedThing Graph HGNC:1062 biolink:NamedThing Graph HGNC:10648 biolink:NamedThing Graph HGNC:10664 biolink:NamedThing Graph HGNC:10669 biolink:NamedThing Graph HGNC:1067 biolink:NamedThing Graph HGNC:10671 biolink:NamedThing Graph HGNC:1068 biolink:NamedThing Graph HGNC:10680 biolink:NamedThing Graph HGNC:10681 biolink:NamedThing Graph HGNC:10682 biolink:NamedThing Graph HGNC:10683 biolink:NamedThing Graph HGNC:10701 biolink:NamedThing Graph HGNC:10702 biolink:NamedThing Graph HGNC:10706 biolink:NamedThing Graph HGNC:1071 biolink:NamedThing Graph HGNC:10723 biolink:NamedThing Graph HGNC:10729 biolink:NamedThing Graph HGNC:1076 biolink:NamedThing Graph HGNC:1077 biolink:NamedThing Graph HGNC:10771 biolink:NamedThing Graph HGNC:10778 biolink:NamedThing Graph HGNC:1078 biolink:NamedThing Graph HGNC:10799 biolink:NamedThing Graph HGNC:10801 biolink:NamedThing Graph HGNC:10805 biolink:NamedThing Graph HGNC:10806 biolink:NamedThing Graph HGNC:10807 biolink:NamedThing Graph HGNC:10808 biolink:NamedThing Graph HGNC:10809 biolink:NamedThing Graph HGNC:10817 biolink:NamedThing Graph HGNC:10818 biolink:NamedThing Graph HGNC:10820 biolink:NamedThing Graph HGNC:10825 biolink:NamedThing Graph HGNC:10848 biolink:NamedThing Graph HGNC:10856 biolink:NamedThing Graph HGNC:10872 biolink:NamedThing Graph HGNC:10879 biolink:NamedThing Graph HGNC:10882 biolink:NamedThing Graph HGNC:10887 biolink:NamedThing Graph HGNC:10889 biolink:NamedThing Graph HGNC:10891 biolink:NamedThing Graph HGNC:10892 biolink:NamedThing Graph HGNC:10896 biolink:NamedThing Graph HGNC:10898 biolink:NamedThing Graph HGNC:1090 biolink:NamedThing Graph HGNC:10906 biolink:NamedThing Graph HGNC:10907 biolink:NamedThing Graph HGNC:10908 biolink:NamedThing Graph HGNC:10909 biolink:NamedThing Graph HGNC:10910 biolink:NamedThing Graph HGNC:10912 biolink:NamedThing Graph HGNC:10914 biolink:NamedThing Graph HGNC:1092 biolink:NamedThing Graph HGNC:10922 biolink:NamedThing Graph HGNC:10923 biolink:NamedThing Graph HGNC:1093 biolink:NamedThing Graph HGNC:10933 biolink:NamedThing Graph HGNC:10936 biolink:NamedThing Graph HGNC:10938 biolink:NamedThing Graph HGNC:10939 biolink:NamedThing Graph HGNC:10940 biolink:NamedThing Graph HGNC:10941 biolink:NamedThing Graph HGNC:10942 biolink:NamedThing Graph HGNC:10947 biolink:NamedThing Graph HGNC:10955 biolink:NamedThing Graph HGNC:10964 biolink:NamedThing Graph HGNC:10969 biolink:NamedThing Graph HGNC:1097 biolink:NamedThing Graph HGNC:10975 biolink:NamedThing Graph HGNC:10978 biolink:NamedThing Graph HGNC:10979 biolink:NamedThing Graph HGNC:10982 biolink:NamedThing Graph HGNC:10983 biolink:NamedThing Graph HGNC:10985 biolink:NamedThing Graph HGNC:10989 biolink:NamedThing Graph HGNC:10990 biolink:NamedThing Graph HGNC:10993 biolink:NamedThing Graph HGNC:10994 biolink:NamedThing Graph HGNC:10998 biolink:NamedThing Graph HGNC:1100 biolink:NamedThing Graph HGNC:11005 biolink:NamedThing Graph HGNC:11006 biolink:NamedThing Graph HGNC:1101 biolink:NamedThing Graph HGNC:11013 biolink:NamedThing Graph HGNC:11019 biolink:NamedThing Graph HGNC:11020 biolink:NamedThing Graph HGNC:11021 biolink:NamedThing Graph HGNC:11022 biolink:NamedThing Graph HGNC:11023 biolink:NamedThing Graph HGNC:11027 biolink:NamedThing Graph HGNC:11030 biolink:NamedThing Graph HGNC:11036 biolink:NamedThing Graph HGNC:11037 biolink:NamedThing Graph HGNC:11040 biolink:NamedThing Graph HGNC:11042 biolink:NamedThing Graph HGNC:11048 biolink:NamedThing Graph HGNC:11049 biolink:NamedThing Graph HGNC:11050 biolink:NamedThing Graph HGNC:11051 biolink:NamedThing Graph HGNC:11055 biolink:NamedThing Graph HGNC:11056 biolink:NamedThing Graph HGNC:11065 biolink:NamedThing Graph HGNC:11071 biolink:NamedThing Graph HGNC:11073 biolink:NamedThing Graph HGNC:11075 biolink:NamedThing Graph HGNC:11079 biolink:NamedThing Graph HGNC:11094 biolink:NamedThing Graph HGNC:11098 biolink:NamedThing Graph HGNC:11100 biolink:NamedThing Graph HGNC:11102 biolink:NamedThing Graph HGNC:11103 biolink:NamedThing Graph HGNC:11104 biolink:NamedThing Graph HGNC:11105 biolink:NamedThing Graph HGNC:11109 biolink:NamedThing Graph HGNC:11110 biolink:NamedThing Graph HGNC:11111 biolink:NamedThing Graph HGNC:11114 biolink:NamedThing Graph HGNC:11117 biolink:NamedThing Graph HGNC:11119 biolink:NamedThing Graph HGNC:11120 biolink:NamedThing Graph HGNC:11122 biolink:NamedThing Graph HGNC:11123 biolink:NamedThing Graph HGNC:11132 biolink:NamedThing Graph HGNC:11133 biolink:NamedThing Graph HGNC:11138 biolink:NamedThing Graph HGNC:11142 biolink:NamedThing Graph HGNC:11153 biolink:NamedThing Graph HGNC:11161 biolink:NamedThing Graph HGNC:11167 biolink:NamedThing Graph HGNC:11179 biolink:NamedThing Graph HGNC:11180 biolink:NamedThing Graph HGNC:11183 biolink:NamedThing Graph HGNC:11187 biolink:NamedThing Graph HGNC:11188 biolink:NamedThing Graph HGNC:11190 biolink:NamedThing Graph HGNC:11191 biolink:NamedThing Graph HGNC:11194 biolink:NamedThing Graph HGNC:11199 biolink:NamedThing Graph HGNC:11201 biolink:NamedThing Graph HGNC:11204 biolink:NamedThing Graph HGNC:11212 biolink:NamedThing Graph HGNC:11219 biolink:NamedThing Graph HGNC:1122 biolink:NamedThing Graph HGNC:11226 biolink:NamedThing Graph HGNC:11231 biolink:NamedThing Graph HGNC:11233 biolink:NamedThing Graph HGNC:11237 biolink:NamedThing Graph HGNC:11244 biolink:NamedThing Graph HGNC:11247 biolink:NamedThing Graph HGNC:11257 biolink:NamedThing Graph HGNC:11270 biolink:NamedThing Graph HGNC:11272 biolink:NamedThing Graph HGNC:11273 biolink:NamedThing Graph HGNC:11274 biolink:NamedThing Graph HGNC:11276 biolink:NamedThing Graph HGNC:11277 biolink:NamedThing Graph HGNC:11278 biolink:NamedThing Graph HGNC:11280 biolink:NamedThing Graph HGNC:11283 biolink:NamedThing Graph HGNC:11285 biolink:NamedThing Graph HGNC:11303 biolink:NamedThing Graph HGNC:11311 biolink:NamedThing Graph HGNC:11326 biolink:NamedThing Graph HGNC:1133 biolink:NamedThing Graph HGNC:11354 biolink:NamedThing Graph HGNC:11356 biolink:NamedThing Graph HGNC:11359 biolink:NamedThing Graph HGNC:11362 biolink:NamedThing Graph HGNC:11363 biolink:NamedThing Graph HGNC:11364 biolink:NamedThing Graph HGNC:11365 biolink:NamedThing Graph HGNC:11367 biolink:NamedThing Graph HGNC:11386 biolink:NamedThing Graph HGNC:11389 biolink:NamedThing Graph HGNC:11391 biolink:NamedThing Graph HGNC:11397 biolink:NamedThing Graph HGNC:11408 biolink:NamedThing Graph HGNC:11411 biolink:NamedThing Graph HGNC:1142 biolink:NamedThing Graph HGNC:11425 biolink:NamedThing Graph HGNC:11427 biolink:NamedThing Graph HGNC:11429 biolink:NamedThing Graph HGNC:11444 biolink:NamedThing Graph HGNC:11445 biolink:NamedThing Graph HGNC:11448 biolink:NamedThing Graph HGNC:11449 biolink:NamedThing Graph HGNC:11460 biolink:NamedThing Graph HGNC:11474 biolink:NamedThing Graph HGNC:11480 biolink:NamedThing Graph HGNC:1149 biolink:NamedThing Graph HGNC:11494 biolink:NamedThing Graph HGNC:11497 biolink:NamedThing Graph HGNC:11503 biolink:NamedThing Graph HGNC:11506 biolink:NamedThing Graph HGNC:11509 biolink:NamedThing Graph HGNC:11510 biolink:NamedThing Graph HGNC:11515 biolink:NamedThing Graph HGNC:1152 biolink:NamedThing Graph HGNC:11521 biolink:NamedThing Graph HGNC:11528 biolink:NamedThing Graph HGNC:11529 biolink:NamedThing Graph HGNC:11530 biolink:NamedThing Graph HGNC:11535 biolink:NamedThing Graph HGNC:11536 biolink:NamedThing Graph HGNC:11538 biolink:NamedThing Graph HGNC:11540 biolink:NamedThing Graph HGNC:11551 biolink:NamedThing Graph HGNC:11559 biolink:NamedThing Graph HGNC:11571 biolink:NamedThing Graph HGNC:11573 biolink:NamedThing Graph HGNC:11577 biolink:NamedThing Graph HGNC:11581 biolink:NamedThing Graph HGNC:11582 biolink:NamedThing Graph HGNC:11584 biolink:NamedThing Graph HGNC:11588 biolink:NamedThing Graph HGNC:11594 biolink:NamedThing Graph HGNC:11595 biolink:NamedThing Graph HGNC:11596 biolink:NamedThing Graph HGNC:11598 biolink:NamedThing Graph HGNC:1160 biolink:NamedThing Graph HGNC:11600 biolink:NamedThing Graph HGNC:11602 biolink:NamedThing Graph HGNC:11603 biolink:NamedThing Graph HGNC:11604 biolink:NamedThing Graph HGNC:11605 biolink:NamedThing Graph HGNC:11608 biolink:NamedThing Graph HGNC:11609 biolink:NamedThing Graph HGNC:1161 biolink:NamedThing Graph HGNC:11610 biolink:NamedThing Graph HGNC:11621 biolink:NamedThing Graph HGNC:11623 biolink:NamedThing Graph HGNC:11630 biolink:NamedThing Graph HGNC:11633 biolink:NamedThing Graph HGNC:11634 biolink:NamedThing Graph HGNC:11642 biolink:NamedThing Graph HGNC:11647 biolink:NamedThing Graph HGNC:11653 biolink:NamedThing Graph HGNC:11654 biolink:NamedThing Graph HGNC:11708 biolink:NamedThing Graph HGNC:1171 biolink:NamedThing Graph HGNC:11714 biolink:NamedThing Graph HGNC:11720 biolink:NamedThing Graph HGNC:11724 biolink:NamedThing Graph HGNC:11727 biolink:NamedThing Graph HGNC:11730 biolink:NamedThing Graph HGNC:11733 biolink:NamedThing Graph HGNC:11740 biolink:NamedThing Graph HGNC:11741 biolink:NamedThing Graph HGNC:11742 biolink:NamedThing Graph HGNC:11743 biolink:NamedThing Graph HGNC:11752 biolink:NamedThing Graph HGNC:11758 biolink:NamedThing Graph HGNC:11762 biolink:NamedThing Graph HGNC:11763 biolink:NamedThing Graph HGNC:11764 biolink:NamedThing Graph HGNC:11766 biolink:NamedThing Graph HGNC:11768 biolink:NamedThing Graph HGNC:11769 biolink:NamedThing Graph HGNC:11771 biolink:NamedThing Graph HGNC:11772 biolink:NamedThing Graph HGNC:11773 biolink:NamedThing Graph HGNC:11776 biolink:NamedThing Graph HGNC:11777 biolink:NamedThing Graph HGNC:11779 biolink:NamedThing Graph HGNC:11781 biolink:NamedThing Graph HGNC:11782 biolink:NamedThing Graph HGNC:11784 biolink:NamedThing Graph HGNC:11791 biolink:NamedThing Graph HGNC:11796 biolink:NamedThing Graph HGNC:11799 biolink:NamedThing Graph HGNC:118 biolink:NamedThing Graph HGNC:11802 biolink:NamedThing Graph HGNC:11811 biolink:NamedThing Graph HGNC:11817 biolink:NamedThing Graph HGNC:11822 biolink:NamedThing Graph HGNC:11824 biolink:NamedThing Graph HGNC:11825 biolink:NamedThing Graph HGNC:11828 biolink:NamedThing Graph HGNC:11831 biolink:NamedThing Graph HGNC:11834 biolink:NamedThing Graph HGNC:11843 biolink:NamedThing Graph HGNC:11847 biolink:NamedThing Graph HGNC:11848 biolink:NamedThing Graph HGNC:11850 biolink:NamedThing Graph HGNC:11851 biolink:NamedThing Graph HGNC:11854 biolink:NamedThing Graph HGNC:11896 biolink:NamedThing Graph HGNC:119 biolink:NamedThing Graph HGNC:11908 biolink:NamedThing Graph HGNC:11909 biolink:NamedThing Graph HGNC:11916 biolink:NamedThing Graph HGNC:11918 biolink:NamedThing Graph HGNC:11919 biolink:NamedThing Graph HGNC:11922 biolink:NamedThing Graph HGNC:11926 biolink:NamedThing Graph HGNC:11935 biolink:NamedThing Graph HGNC:11937 biolink:NamedThing Graph HGNC:11943 biolink:NamedThing Graph HGNC:11947 biolink:NamedThing Graph HGNC:11948 biolink:NamedThing Graph HGNC:11949 biolink:NamedThing Graph HGNC:11957 biolink:NamedThing Graph HGNC:11960 biolink:NamedThing Graph HGNC:11976 biolink:NamedThing Graph HGNC:11990 biolink:NamedThing Graph HGNC:11998 biolink:NamedThing Graph HGNC:120 biolink:NamedThing Graph HGNC:12009 biolink:NamedThing Graph HGNC:12010 biolink:NamedThing Graph HGNC:12011 biolink:NamedThing Graph HGNC:12012 biolink:NamedThing Graph HGNC:12013 biolink:NamedThing Graph HGNC:12014 biolink:NamedThing Graph HGNC:12015 biolink:NamedThing Graph HGNC:12029 biolink:NamedThing Graph HGNC:12033 biolink:NamedThing Graph HGNC:12261 biolink:NamedThing Graph HGNC:12266 biolink:NamedThing Graph HGNC:12269 biolink:NamedThing Graph HGNC:1228 biolink:NamedThing Graph HGNC:12298 biolink:NamedThing Graph HGNC:123 biolink:NamedThing Graph HGNC:12303 biolink:NamedThing Graph HGNC:12305 biolink:NamedThing Graph HGNC:12310 biolink:NamedThing Graph HGNC:1232 biolink:NamedThing Graph HGNC:12335 biolink:NamedThing Graph HGNC:12338 biolink:NamedThing Graph HGNC:12340 biolink:NamedThing Graph HGNC:12362 biolink:NamedThing Graph HGNC:12367 biolink:NamedThing Graph HGNC:12370 biolink:NamedThing Graph HGNC:12371 biolink:NamedThing Graph HGNC:12372 biolink:NamedThing Graph HGNC:12373 biolink:NamedThing Graph HGNC:12382 biolink:NamedThing Graph HGNC:12399 biolink:NamedThing Graph HGNC:124 biolink:NamedThing Graph HGNC:12403 biolink:NamedThing Graph HGNC:12404 biolink:NamedThing Graph HGNC:12405 biolink:NamedThing Graph HGNC:12406 biolink:NamedThing Graph HGNC:12407 biolink:NamedThing Graph HGNC:12410 biolink:NamedThing Graph HGNC:12412 biolink:NamedThing Graph HGNC:12417 biolink:NamedThing Graph HGNC:12420 biolink:NamedThing Graph HGNC:12423 biolink:NamedThing Graph HGNC:12428 biolink:NamedThing Graph HGNC:12440 biolink:NamedThing Graph HGNC:12442 biolink:NamedThing Graph HGNC:12450 biolink:NamedThing Graph HGNC:1246 biolink:NamedThing Graph HGNC:12463 biolink:NamedThing Graph HGNC:12469 biolink:NamedThing Graph HGNC:1247 biolink:NamedThing Graph HGNC:12472 biolink:NamedThing Graph HGNC:1248 biolink:NamedThing Graph HGNC:12496 biolink:NamedThing Graph HGNC:12502 biolink:NamedThing Graph HGNC:12509 biolink:NamedThing Graph HGNC:12513 biolink:NamedThing Graph HGNC:12530 biolink:NamedThing Graph HGNC:12559 biolink:NamedThing Graph HGNC:12563 biolink:NamedThing Graph HGNC:12565 biolink:NamedThing Graph HGNC:12572 biolink:NamedThing Graph HGNC:12582 biolink:NamedThing Graph HGNC:12586 biolink:NamedThing Graph HGNC:12591 biolink:NamedThing Graph HGNC:12592 biolink:NamedThing Graph HGNC:12593 biolink:NamedThing Graph HGNC:12597 biolink:NamedThing Graph HGNC:1260 biolink:NamedThing Graph HGNC:12601 biolink:NamedThing Graph HGNC:12605 biolink:NamedThing Graph HGNC:12630 biolink:NamedThing Graph HGNC:12632 biolink:NamedThing Graph HGNC:12637 biolink:NamedThing Graph HGNC:12642 biolink:NamedThing Graph HGNC:12649 biolink:NamedThing Graph HGNC:12660 biolink:NamedThing Graph HGNC:12665 biolink:NamedThing Graph HGNC:12666 biolink:NamedThing Graph HGNC:12679 biolink:NamedThing Graph HGNC:1268 biolink:NamedThing Graph HGNC:12680 biolink:NamedThing Graph HGNC:12682 biolink:NamedThing Graph HGNC:12687 biolink:NamedThing Graph HGNC:12692 biolink:NamedThing Graph HGNC:12698 biolink:NamedThing Graph HGNC:12703 biolink:NamedThing Graph HGNC:12712 biolink:NamedThing Graph HGNC:12718 biolink:NamedThing Graph HGNC:12723 biolink:NamedThing Graph HGNC:12726 biolink:NamedThing Graph HGNC:12731 biolink:NamedThing Graph HGNC:12736 biolink:NamedThing Graph HGNC:12762 biolink:NamedThing Graph HGNC:12765 biolink:NamedThing Graph HGNC:12771 biolink:NamedThing Graph HGNC:12774 biolink:NamedThing Graph HGNC:12775 biolink:NamedThing Graph HGNC:12782 biolink:NamedThing Graph HGNC:12783 biolink:NamedThing Graph HGNC:12784 biolink:NamedThing Graph HGNC:12786 biolink:NamedThing Graph HGNC:12791 biolink:NamedThing Graph HGNC:12796 biolink:NamedThing Graph HGNC:12799 biolink:NamedThing Graph HGNC:12801 biolink:NamedThing Graph HGNC:12805 biolink:NamedThing Graph HGNC:12811 biolink:NamedThing Graph HGNC:12814 biolink:NamedThing Graph HGNC:12816 biolink:NamedThing Graph HGNC:12823 biolink:NamedThing Graph HGNC:12827 biolink:NamedThing Graph HGNC:12829 biolink:NamedThing Graph HGNC:12830 biolink:NamedThing Graph HGNC:12831 biolink:NamedThing Graph HGNC:12840 biolink:NamedThing Graph HGNC:12843 biolink:NamedThing Graph HGNC:12858 biolink:NamedThing Graph HGNC:12872 biolink:NamedThing Graph HGNC:12873 biolink:NamedThing Graph HGNC:12874 biolink:NamedThing Graph HGNC:12877 biolink:NamedThing Graph HGNC:129 biolink:NamedThing Graph HGNC:12926 biolink:NamedThing Graph HGNC:12930 biolink:NamedThing Graph HGNC:12933 biolink:NamedThing Graph HGNC:12974 biolink:NamedThing Graph HGNC:130 biolink:NamedThing Graph HGNC:1301 biolink:NamedThing Graph HGNC:13013 biolink:NamedThing Graph HGNC:13030 biolink:NamedThing Graph HGNC:1304 biolink:NamedThing Graph HGNC:13128 biolink:NamedThing Graph HGNC:13156 biolink:NamedThing Graph HGNC:13164 biolink:NamedThing Graph HGNC:13176 biolink:NamedThing Graph HGNC:1318 biolink:NamedThing Graph HGNC:13187 biolink:NamedThing Graph HGNC:132 biolink:NamedThing Graph HGNC:13201 biolink:NamedThing Graph HGNC:13203 biolink:NamedThing Graph HGNC:1321 biolink:NamedThing Graph HGNC:13210 biolink:NamedThing Graph HGNC:13211 biolink:NamedThing Graph HGNC:13221 biolink:NamedThing Graph HGNC:13222 biolink:NamedThing Graph HGNC:1323 biolink:NamedThing Graph HGNC:1324 biolink:NamedThing Graph HGNC:13243 biolink:NamedThing Graph HGNC:13254 biolink:NamedThing Graph HGNC:13273 biolink:NamedThing Graph HGNC:13281 biolink:NamedThing Graph HGNC:1330 biolink:NamedThing Graph HGNC:1331 biolink:NamedThing Graph HGNC:13339 biolink:NamedThing Graph HGNC:13345 biolink:NamedThing Graph HGNC:13356 biolink:NamedThing Graph HGNC:13387 biolink:NamedThing Graph HGNC:1339 biolink:NamedThing Graph HGNC:13394 biolink:NamedThing Graph HGNC:13398 biolink:NamedThing Graph HGNC:13406 biolink:NamedThing Graph HGNC:13420 biolink:NamedThing Graph HGNC:13429 biolink:NamedThing Graph HGNC:1343 biolink:NamedThing Graph HGNC:13433 biolink:NamedThing Graph HGNC:13436 biolink:NamedThing Graph HGNC:13444 biolink:NamedThing Graph HGNC:13446 biolink:NamedThing Graph HGNC:1346 biolink:NamedThing Graph HGNC:13478 biolink:NamedThing Graph HGNC:1348 biolink:NamedThing Graph HGNC:13481 biolink:NamedThing Graph HGNC:13486 biolink:NamedThing Graph HGNC:13487 biolink:NamedThing Graph HGNC:1349 biolink:NamedThing Graph HGNC:13503 biolink:NamedThing Graph HGNC:13517 biolink:NamedThing Graph HGNC:1352 biolink:NamedThing Graph HGNC:1353 biolink:NamedThing Graph HGNC:13530 biolink:NamedThing Graph HGNC:13533 biolink:NamedThing Graph HGNC:13556 biolink:NamedThing Graph HGNC:1356 biolink:NamedThing Graph HGNC:1358 biolink:NamedThing Graph HGNC:13586 biolink:NamedThing Graph HGNC:13601 biolink:NamedThing Graph HGNC:1362 biolink:NamedThing Graph HGNC:1366 biolink:NamedThing Graph HGNC:13666 biolink:NamedThing Graph HGNC:13681 biolink:NamedThing Graph HGNC:1371 biolink:NamedThing Graph HGNC:13711 biolink:NamedThing Graph HGNC:13723 biolink:NamedThing Graph HGNC:1373 biolink:NamedThing Graph HGNC:13733 biolink:NamedThing Graph HGNC:13743 biolink:NamedThing Graph HGNC:1375 biolink:NamedThing Graph HGNC:1377 biolink:NamedThing Graph HGNC:13771 biolink:NamedThing Graph HGNC:13780 biolink:NamedThing Graph HGNC:13797 biolink:NamedThing Graph HGNC:13806 biolink:NamedThing Graph HGNC:13815 biolink:NamedThing Graph HGNC:13818 biolink:NamedThing Graph HGNC:1382 biolink:NamedThing Graph HGNC:13825 biolink:NamedThing Graph HGNC:13829 biolink:NamedThing Graph HGNC:13830 biolink:NamedThing Graph HGNC:13831 biolink:NamedThing Graph HGNC:13841 biolink:NamedThing Graph HGNC:1385 biolink:NamedThing Graph HGNC:1386 biolink:NamedThing Graph HGNC:13872 biolink:NamedThing Graph HGNC:13875 biolink:NamedThing Graph HGNC:1388 biolink:NamedThing Graph HGNC:13887 biolink:NamedThing Graph HGNC:1389 biolink:NamedThing Graph HGNC:13890 biolink:NamedThing Graph HGNC:1390 biolink:NamedThing Graph HGNC:13902 biolink:NamedThing Graph HGNC:1391 biolink:NamedThing Graph HGNC:1393 biolink:NamedThing Graph HGNC:1394 biolink:NamedThing Graph HGNC:1395 biolink:NamedThing Graph HGNC:1397 biolink:NamedThing Graph HGNC:13993 biolink:NamedThing Graph HGNC:13997 biolink:NamedThing Graph HGNC:14000 biolink:NamedThing Graph HGNC:14004 biolink:NamedThing Graph HGNC:1402 biolink:NamedThing Graph HGNC:14025 biolink:NamedThing Graph HGNC:1404 biolink:NamedThing Graph HGNC:14048 biolink:NamedThing Graph HGNC:1406 biolink:NamedThing Graph HGNC:14064 biolink:NamedThing Graph HGNC:14074 biolink:NamedThing Graph HGNC:14082 biolink:NamedThing Graph HGNC:14103 biolink:NamedThing Graph HGNC:14124 biolink:NamedThing Graph HGNC:14135 biolink:NamedThing Graph HGNC:14153 biolink:NamedThing Graph HGNC:14154 biolink:NamedThing Graph HGNC:14198 biolink:NamedThing Graph HGNC:14202 biolink:NamedThing Graph HGNC:14203 biolink:NamedThing Graph HGNC:1421 biolink:NamedThing Graph HGNC:14211 biolink:NamedThing Graph HGNC:14234 biolink:NamedThing Graph HGNC:1424 biolink:NamedThing Graph HGNC:14244 biolink:NamedThing Graph HGNC:14253 biolink:NamedThing Graph HGNC:14255 biolink:NamedThing Graph HGNC:14258 biolink:NamedThing Graph HGNC:14262 biolink:NamedThing Graph HGNC:14263 biolink:NamedThing Graph HGNC:14270 biolink:NamedThing Graph HGNC:14282 biolink:NamedThing Graph HGNC:14287 biolink:NamedThing Graph HGNC:14289 biolink:NamedThing Graph HGNC:14291 biolink:NamedThing Graph HGNC:14294 biolink:NamedThing Graph HGNC:14295 biolink:NamedThing Graph HGNC:143 biolink:NamedThing Graph HGNC:14304 biolink:NamedThing Graph HGNC:14312 biolink:NamedThing Graph HGNC:14341 biolink:NamedThing Graph HGNC:14344 biolink:NamedThing Graph HGNC:14348 biolink:NamedThing Graph HGNC:14357 biolink:NamedThing Graph HGNC:14361 biolink:NamedThing Graph HGNC:14372 biolink:NamedThing Graph HGNC:14373 biolink:NamedThing Graph HGNC:14374 biolink:NamedThing Graph HGNC:14376 biolink:NamedThing Graph HGNC:14377 biolink:NamedThing Graph HGNC:14388 biolink:NamedThing Graph HGNC:144 biolink:NamedThing Graph HGNC:14409 biolink:NamedThing Graph HGNC:14412 biolink:NamedThing Graph HGNC:1442 biolink:NamedThing Graph HGNC:14432 biolink:NamedThing Graph HGNC:1445 biolink:NamedThing Graph HGNC:14450 biolink:NamedThing Graph HGNC:14468 biolink:NamedThing Graph HGNC:14508 biolink:NamedThing Graph HGNC:14537 biolink:NamedThing Graph HGNC:14539 biolink:NamedThing Graph HGNC:14540 biolink:NamedThing Graph HGNC:14544 biolink:NamedThing Graph HGNC:14550 biolink:NamedThing Graph HGNC:14558 biolink:NamedThing Graph HGNC:14561 biolink:NamedThing Graph HGNC:14579 biolink:NamedThing Graph HGNC:14581 biolink:NamedThing Graph HGNC:14583 biolink:NamedThing Graph HGNC:14604 biolink:NamedThing Graph HGNC:14628 biolink:NamedThing Graph HGNC:14630 biolink:NamedThing Graph HGNC:14631 biolink:NamedThing Graph HGNC:14632 biolink:NamedThing Graph HGNC:14637 biolink:NamedThing Graph HGNC:14673 biolink:NamedThing Graph HGNC:14674 biolink:NamedThing Graph HGNC:14677 biolink:NamedThing Graph HGNC:1476 biolink:NamedThing Graph HGNC:1477 biolink:NamedThing Graph HGNC:1480 biolink:NamedThing Graph HGNC:1482 biolink:NamedThing Graph HGNC:14857 biolink:NamedThing Graph HGNC:14872 biolink:NamedThing Graph HGNC:14880 biolink:NamedThing Graph HGNC:14881 biolink:NamedThing Graph HGNC:14888 biolink:NamedThing Graph HGNC:14889 biolink:NamedThing Graph HGNC:14897 biolink:NamedThing Graph HGNC:14906 biolink:NamedThing Graph HGNC:1492 biolink:NamedThing Graph HGNC:14938 biolink:NamedThing Graph HGNC:1494 biolink:NamedThing Graph HGNC:14951 biolink:NamedThing Graph HGNC:14963 biolink:NamedThing Graph HGNC:14966 biolink:NamedThing Graph HGNC:1497 biolink:NamedThing Graph HGNC:14974 biolink:NamedThing Graph HGNC:14977 biolink:NamedThing Graph HGNC:14988 biolink:NamedThing Graph HGNC:1500 biolink:NamedThing Graph HGNC:1502 biolink:NamedThing Graph HGNC:1509 biolink:NamedThing Graph HGNC:1512 biolink:NamedThing Graph HGNC:1513 biolink:NamedThing Graph HGNC:1514 biolink:NamedThing Graph HGNC:1515 biolink:NamedThing Graph HGNC:1516 biolink:NamedThing Graph HGNC:1527 biolink:NamedThing Graph HGNC:1529 biolink:NamedThing Graph HGNC:1530 biolink:NamedThing Graph HGNC:1540 biolink:NamedThing Graph HGNC:1541 biolink:NamedThing Graph HGNC:15446 biolink:NamedThing Graph HGNC:15454 biolink:NamedThing Graph HGNC:15455 biolink:NamedThing Graph HGNC:15459 biolink:NamedThing Graph HGNC:1546 biolink:NamedThing Graph HGNC:15464 biolink:NamedThing Graph HGNC:15465 biolink:NamedThing Graph HGNC:15469 biolink:NamedThing Graph HGNC:15480 biolink:NamedThing Graph HGNC:15492 biolink:NamedThing Graph HGNC:1550 biolink:NamedThing Graph HGNC:15505 biolink:NamedThing Graph HGNC:15506 biolink:NamedThing Graph HGNC:15508 biolink:NamedThing Graph HGNC:15512 biolink:NamedThing Graph HGNC:15516 biolink:NamedThing Graph HGNC:15517 biolink:NamedThing Graph HGNC:1552 biolink:NamedThing Graph HGNC:15520 biolink:NamedThing Graph HGNC:15532 biolink:NamedThing Graph HGNC:15533 biolink:NamedThing Graph HGNC:15559 biolink:NamedThing Graph HGNC:15561 biolink:NamedThing Graph HGNC:15573 biolink:NamedThing Graph HGNC:15597 biolink:NamedThing Graph HGNC:15598 biolink:NamedThing Graph HGNC:15625 biolink:NamedThing Graph HGNC:15626 biolink:NamedThing Graph HGNC:15646 biolink:NamedThing Graph HGNC:15672 biolink:NamedThing Graph HGNC:15685 biolink:NamedThing Graph HGNC:15710 biolink:NamedThing Graph HGNC:15714 biolink:NamedThing Graph HGNC:15718 biolink:NamedThing Graph HGNC:1573 biolink:NamedThing Graph HGNC:15761 biolink:NamedThing Graph HGNC:15766 biolink:NamedThing Graph HGNC:15804 biolink:NamedThing Graph HGNC:15807 biolink:NamedThing Graph HGNC:15808 biolink:NamedThing Graph HGNC:1583 biolink:NamedThing Graph HGNC:15832 biolink:NamedThing Graph HGNC:15836 biolink:NamedThing Graph HGNC:15840 biolink:NamedThing Graph HGNC:15844 biolink:NamedThing Graph HGNC:15853 biolink:NamedThing Graph HGNC:15860 biolink:NamedThing Graph HGNC:15864 biolink:NamedThing Graph HGNC:15865 biolink:NamedThing Graph HGNC:15868 biolink:NamedThing Graph HGNC:15888 biolink:NamedThing Graph HGNC:15889 biolink:NamedThing Graph HGNC:15894 biolink:NamedThing Graph HGNC:15899 biolink:NamedThing Graph HGNC:15901 biolink:NamedThing Graph HGNC:15911 biolink:NamedThing Graph HGNC:15917 biolink:NamedThing Graph HGNC:15924 biolink:NamedThing Graph HGNC:15925 biolink:NamedThing Graph HGNC:15946 biolink:NamedThing Graph HGNC:15954 biolink:NamedThing Graph HGNC:1596 biolink:NamedThing Graph HGNC:15968 biolink:NamedThing Graph HGNC:15974 biolink:NamedThing Graph HGNC:15977 biolink:NamedThing Graph HGNC:15979 biolink:NamedThing Graph HGNC:15984 biolink:NamedThing Graph HGNC:15993 biolink:NamedThing Graph HGNC:15999 biolink:NamedThing Graph HGNC:160 biolink:NamedThing Graph HGNC:16001 biolink:NamedThing Graph HGNC:16002 biolink:NamedThing Graph HGNC:16035 biolink:NamedThing Graph HGNC:1606 biolink:NamedThing Graph HGNC:16068 biolink:NamedThing Graph HGNC:16075 biolink:NamedThing Graph HGNC:16084 biolink:NamedThing Graph HGNC:16088 biolink:NamedThing Graph HGNC:16133 biolink:NamedThing Graph HGNC:16135 biolink:NamedThing Graph HGNC:16171 biolink:NamedThing Graph HGNC:16175 biolink:NamedThing Graph HGNC:1618 biolink:NamedThing Graph HGNC:16187 biolink:NamedThing Graph HGNC:16192 biolink:NamedThing Graph HGNC:16205 biolink:NamedThing Graph HGNC:16232 biolink:NamedThing Graph HGNC:16252 biolink:NamedThing Graph HGNC:16255 biolink:NamedThing Graph HGNC:16257 biolink:NamedThing Graph HGNC:16262 biolink:NamedThing Graph HGNC:16266 biolink:NamedThing Graph HGNC:16268 biolink:NamedThing Graph HGNC:16280 biolink:NamedThing Graph HGNC:16287 biolink:NamedThing Graph HGNC:16297 biolink:NamedThing Graph HGNC:163 biolink:NamedThing Graph HGNC:1630 biolink:NamedThing Graph HGNC:1632 biolink:NamedThing Graph HGNC:1633 biolink:NamedThing Graph HGNC:16353 biolink:NamedThing Graph HGNC:16356 biolink:NamedThing Graph HGNC:16361 biolink:NamedThing Graph HGNC:16369 biolink:NamedThing Graph HGNC:16378 biolink:NamedThing Graph HGNC:16380 biolink:NamedThing Graph HGNC:16391 biolink:NamedThing Graph HGNC:16393 biolink:NamedThing Graph HGNC:164 biolink:NamedThing Graph HGNC:16400 biolink:NamedThing Graph HGNC:16404 biolink:NamedThing Graph HGNC:1641 biolink:NamedThing Graph HGNC:16412 biolink:NamedThing Graph HGNC:16429 biolink:NamedThing Graph HGNC:16438 biolink:NamedThing Graph HGNC:16446 biolink:NamedThing Graph HGNC:16472 biolink:NamedThing Graph HGNC:16473 biolink:NamedThing Graph HGNC:16499 biolink:NamedThing Graph HGNC:16510 biolink:NamedThing Graph HGNC:16512 biolink:NamedThing Graph HGNC:16513 biolink:NamedThing Graph HGNC:16517 biolink:NamedThing Graph HGNC:166 biolink:NamedThing Graph HGNC:1663 biolink:NamedThing Graph HGNC:16636 biolink:NamedThing Graph HGNC:16644 biolink:NamedThing Graph HGNC:1665 biolink:NamedThing Graph HGNC:16650 biolink:NamedThing Graph HGNC:16691 biolink:NamedThing Graph HGNC:16692 biolink:NamedThing Graph HGNC:16695 biolink:NamedThing Graph HGNC:16700 biolink:NamedThing Graph HGNC:16725 biolink:NamedThing Graph HGNC:1673 biolink:NamedThing Graph HGNC:16732 biolink:NamedThing Graph HGNC:1674 biolink:NamedThing Graph HGNC:1675 biolink:NamedThing Graph HGNC:16762 biolink:NamedThing Graph HGNC:1677 biolink:NamedThing Graph HGNC:1678 biolink:NamedThing Graph HGNC:16783 biolink:NamedThing Graph HGNC:16791 biolink:NamedThing Graph HGNC:16808 biolink:NamedThing Graph HGNC:16812 biolink:NamedThing Graph HGNC:16841 biolink:NamedThing Graph HGNC:16873 biolink:NamedThing Graph HGNC:16876 biolink:NamedThing Graph HGNC:16877 biolink:NamedThing Graph HGNC:16882 biolink:NamedThing Graph HGNC:1689 biolink:NamedThing Graph HGNC:16892 biolink:NamedThing Graph HGNC:16901 biolink:NamedThing Graph HGNC:16902 biolink:NamedThing Graph HGNC:16905 biolink:NamedThing Graph HGNC:16912 biolink:NamedThing Graph HGNC:16915 biolink:NamedThing Graph HGNC:16940 biolink:NamedThing Graph HGNC:16947 biolink:NamedThing Graph HGNC:16950 biolink:NamedThing Graph HGNC:16966 biolink:NamedThing Graph HGNC:16974 biolink:NamedThing Graph HGNC:1698 biolink:NamedThing Graph HGNC:1699 biolink:NamedThing Graph HGNC:16993 biolink:NamedThing Graph HGNC:16999 biolink:NamedThing Graph HGNC:17009 biolink:NamedThing Graph HGNC:1701 biolink:NamedThing Graph HGNC:17019 biolink:NamedThing Graph HGNC:17020 biolink:NamedThing Graph HGNC:17022 biolink:NamedThing Graph HGNC:17035 biolink:NamedThing Graph HGNC:17042 biolink:NamedThing Graph HGNC:17043 biolink:NamedThing Graph HGNC:17057 biolink:NamedThing Graph HGNC:1706 biolink:NamedThing Graph HGNC:17063 biolink:NamedThing Graph HGNC:17068 biolink:NamedThing Graph HGNC:17073 biolink:NamedThing Graph HGNC:17075 biolink:NamedThing Graph HGNC:17084 biolink:NamedThing Graph HGNC:17089 biolink:NamedThing Graph HGNC:17091 biolink:NamedThing Graph HGNC:17095 biolink:NamedThing Graph HGNC:17098 biolink:NamedThing Graph HGNC:171 biolink:NamedThing Graph HGNC:17104 biolink:NamedThing Graph HGNC:17109 biolink:NamedThing Graph HGNC:17110 biolink:NamedThing Graph HGNC:17129 biolink:NamedThing Graph HGNC:1713 biolink:NamedThing Graph HGNC:17142 biolink:NamedThing Graph HGNC:17146 biolink:NamedThing Graph HGNC:17151 biolink:NamedThing Graph HGNC:17158 biolink:NamedThing Graph HGNC:17168 biolink:NamedThing Graph HGNC:17175 biolink:NamedThing Graph HGNC:1718 biolink:NamedThing Graph HGNC:17192 biolink:NamedThing Graph HGNC:17194 biolink:NamedThing Graph HGNC:17198 biolink:NamedThing Graph HGNC:17208 biolink:NamedThing Graph HGNC:17210 biolink:NamedThing Graph HGNC:17213 biolink:NamedThing Graph HGNC:17233 biolink:NamedThing Graph HGNC:17245 biolink:NamedThing Graph HGNC:17264 biolink:NamedThing Graph HGNC:17272 biolink:NamedThing Graph HGNC:17282 biolink:NamedThing Graph HGNC:17284 biolink:NamedThing Graph HGNC:17288 biolink:NamedThing Graph HGNC:17296 biolink:NamedThing Graph HGNC:17321 biolink:NamedThing Graph HGNC:17327 biolink:NamedThing Graph HGNC:17328 biolink:NamedThing Graph HGNC:17340 biolink:NamedThing Graph HGNC:17341 biolink:NamedThing Graph HGNC:17342 biolink:NamedThing Graph HGNC:17348 biolink:NamedThing Graph HGNC:17349 biolink:NamedThing Graph HGNC:17358 biolink:NamedThing Graph HGNC:1736 biolink:NamedThing Graph HGNC:17366 biolink:NamedThing Graph HGNC:17367 biolink:NamedThing Graph HGNC:1739 biolink:NamedThing Graph HGNC:17397 biolink:NamedThing Graph HGNC:174 biolink:NamedThing Graph HGNC:17412 biolink:NamedThing Graph HGNC:17416 biolink:NamedThing Graph HGNC:1742 biolink:NamedThing Graph HGNC:1744 biolink:NamedThing Graph HGNC:1748 biolink:NamedThing Graph HGNC:17493 biolink:NamedThing Graph HGNC:17494 biolink:NamedThing Graph HGNC:175 biolink:NamedThing Graph HGNC:17513 biolink:NamedThing Graph HGNC:1754 biolink:NamedThing Graph HGNC:17582 biolink:NamedThing Graph HGNC:1759 biolink:NamedThing Graph HGNC:17616 biolink:NamedThing Graph HGNC:17619 biolink:NamedThing Graph HGNC:1762 biolink:NamedThing Graph HGNC:17642 biolink:NamedThing Graph HGNC:17646 biolink:NamedThing Graph HGNC:17652 biolink:NamedThing Graph HGNC:17655 biolink:NamedThing Graph HGNC:17697 biolink:NamedThing Graph HGNC:177 biolink:NamedThing Graph HGNC:1773 biolink:NamedThing Graph HGNC:1774 biolink:NamedThing Graph HGNC:17748 biolink:NamedThing Graph HGNC:17755 biolink:NamedThing Graph HGNC:17759 biolink:NamedThing Graph HGNC:17768 biolink:NamedThing Graph HGNC:1777 biolink:NamedThing Graph HGNC:17772 biolink:NamedThing Graph HGNC:17797 biolink:NamedThing Graph HGNC:17800 biolink:NamedThing Graph HGNC:17820 biolink:NamedThing Graph HGNC:1785 biolink:NamedThing Graph HGNC:1786 biolink:NamedThing Graph HGNC:17861 biolink:NamedThing Graph HGNC:17869 biolink:NamedThing Graph HGNC:1787 biolink:NamedThing Graph HGNC:17870 biolink:NamedThing Graph HGNC:17877 biolink:NamedThing Graph HGNC:17893 biolink:NamedThing Graph HGNC:17928 biolink:NamedThing Graph HGNC:17935 biolink:NamedThing Graph HGNC:17944 biolink:NamedThing Graph HGNC:17964 biolink:NamedThing Graph HGNC:17966 biolink:NamedThing Graph HGNC:17967 biolink:NamedThing Graph HGNC:17975 biolink:NamedThing Graph HGNC:17978 biolink:NamedThing Graph HGNC:17989 biolink:NamedThing Graph HGNC:17993 biolink:NamedThing Graph HGNC:17994 biolink:NamedThing Graph HGNC:17995 biolink:NamedThing Graph HGNC:17996 biolink:NamedThing Graph HGNC:17997 biolink:NamedThing Graph HGNC:1802 biolink:NamedThing Graph HGNC:18021 biolink:NamedThing Graph HGNC:18025 biolink:NamedThing Graph HGNC:18037 biolink:NamedThing Graph HGNC:18040 biolink:NamedThing Graph HGNC:18053 biolink:NamedThing Graph HGNC:18060 biolink:NamedThing Graph HGNC:18062 biolink:NamedThing Graph HGNC:18083 biolink:NamedThing Graph HGNC:18084 biolink:NamedThing Graph HGNC:18085 biolink:NamedThing Graph HGNC:18111 biolink:NamedThing Graph HGNC:18119 biolink:NamedThing Graph HGNC:18121 biolink:NamedThing Graph HGNC:18122 biolink:NamedThing Graph HGNC:18127 biolink:NamedThing Graph HGNC:18130 biolink:NamedThing Graph HGNC:18141 biolink:NamedThing Graph HGNC:18143 biolink:NamedThing Graph HGNC:18145 biolink:NamedThing Graph HGNC:18150 biolink:NamedThing Graph HGNC:18153 biolink:NamedThing Graph HGNC:18169 biolink:NamedThing Graph HGNC:18179 biolink:NamedThing Graph HGNC:18183 biolink:NamedThing Graph HGNC:18187 biolink:NamedThing Graph HGNC:18234 biolink:NamedThing Graph HGNC:18243 biolink:NamedThing Graph HGNC:18248 biolink:NamedThing Graph HGNC:18249 biolink:NamedThing Graph HGNC:18276 biolink:NamedThing Graph HGNC:18286 biolink:NamedThing Graph HGNC:18292 biolink:NamedThing Graph HGNC:18294 biolink:NamedThing Graph HGNC:18305 biolink:NamedThing Graph HGNC:18308 biolink:NamedThing Graph HGNC:18318 biolink:NamedThing Graph HGNC:18324 biolink:NamedThing Graph HGNC:18337 biolink:NamedThing Graph HGNC:18340 biolink:NamedThing Graph HGNC:18348 biolink:NamedThing Graph HGNC:18358 biolink:NamedThing Graph HGNC:1836 biolink:NamedThing Graph HGNC:18362 biolink:NamedThing Graph HGNC:18374 biolink:NamedThing Graph HGNC:1838 biolink:NamedThing Graph HGNC:1839 biolink:NamedThing Graph HGNC:18398 biolink:NamedThing Graph HGNC:18420 biolink:NamedThing Graph HGNC:18423 biolink:NamedThing Graph HGNC:18451 biolink:NamedThing Graph HGNC:18453 biolink:NamedThing Graph HGNC:18455 biolink:NamedThing Graph HGNC:18466 biolink:NamedThing Graph HGNC:18475 biolink:NamedThing Graph HGNC:1848 biolink:NamedThing Graph HGNC:18481 biolink:NamedThing Graph HGNC:18483 biolink:NamedThing Graph HGNC:18505 biolink:NamedThing Graph HGNC:18514 biolink:NamedThing Graph HGNC:18518 biolink:NamedThing Graph HGNC:18539 biolink:NamedThing Graph HGNC:18540 biolink:NamedThing Graph HGNC:18550 biolink:NamedThing Graph HGNC:1856 biolink:NamedThing Graph HGNC:1857 biolink:NamedThing Graph HGNC:18576 biolink:NamedThing Graph HGNC:18591 biolink:NamedThing Graph HGNC:186 biolink:NamedThing Graph HGNC:18603 biolink:NamedThing Graph HGNC:18618 biolink:NamedThing Graph HGNC:18620 biolink:NamedThing Graph HGNC:18621 biolink:NamedThing Graph HGNC:18622 biolink:NamedThing Graph HGNC:18623 biolink:NamedThing Graph HGNC:18625 biolink:NamedThing Graph HGNC:18626 biolink:NamedThing Graph HGNC:18640 biolink:NamedThing Graph HGNC:18647 biolink:NamedThing Graph HGNC:18654 biolink:NamedThing Graph HGNC:18658 biolink:NamedThing Graph HGNC:18662 biolink:NamedThing Graph HGNC:18667 biolink:NamedThing Graph HGNC:18672 biolink:NamedThing Graph HGNC:18674 biolink:NamedThing Graph HGNC:18683 biolink:NamedThing Graph HGNC:18688 biolink:NamedThing Graph HGNC:1869 biolink:NamedThing Graph HGNC:18704 biolink:NamedThing Graph HGNC:18712 biolink:NamedThing Graph HGNC:18713 biolink:NamedThing Graph HGNC:18744 biolink:NamedThing Graph HGNC:18746 biolink:NamedThing Graph HGNC:1875 biolink:NamedThing Graph HGNC:18750 biolink:NamedThing Graph HGNC:18758 biolink:NamedThing Graph HGNC:188 biolink:NamedThing Graph HGNC:18801 biolink:NamedThing Graph HGNC:18802 biolink:NamedThing Graph HGNC:18806 biolink:NamedThing Graph HGNC:18817 biolink:NamedThing Graph HGNC:18828 biolink:NamedThing Graph HGNC:18829 biolink:NamedThing Graph HGNC:1884 biolink:NamedThing Graph HGNC:18858 biolink:NamedThing Graph HGNC:18865 biolink:NamedThing Graph HGNC:18871 biolink:NamedThing Graph HGNC:18873 biolink:NamedThing Graph HGNC:18884 biolink:NamedThing Graph HGNC:18957 biolink:NamedThing Graph HGNC:18969 biolink:NamedThing Graph HGNC:18971 biolink:NamedThing Graph HGNC:18985 biolink:NamedThing Graph HGNC:18986 biolink:NamedThing Graph HGNC:19012 biolink:NamedThing Graph HGNC:19016 biolink:NamedThing Graph HGNC:19027 biolink:NamedThing Graph HGNC:19041 biolink:NamedThing Graph HGNC:19048 biolink:NamedThing Graph HGNC:19073 biolink:NamedThing Graph HGNC:19077 biolink:NamedThing Graph HGNC:1908 biolink:NamedThing Graph HGNC:19082 biolink:NamedThing Graph HGNC:19087 biolink:NamedThing Graph HGNC:19100 biolink:NamedThing Graph HGNC:19102 biolink:NamedThing Graph HGNC:19104 biolink:NamedThing Graph HGNC:1912 biolink:NamedThing Graph HGNC:19125 biolink:NamedThing Graph HGNC:19129 biolink:NamedThing Graph HGNC:19139 biolink:NamedThing Graph HGNC:19141 biolink:NamedThing Graph HGNC:1915 biolink:NamedThing Graph HGNC:19165 biolink:NamedThing Graph HGNC:1917 biolink:NamedThing Graph HGNC:19181 biolink:NamedThing Graph HGNC:19189 biolink:NamedThing Graph HGNC:1919 biolink:NamedThing Graph HGNC:19190 biolink:NamedThing Graph HGNC:19191 biolink:NamedThing Graph HGNC:19218 biolink:NamedThing Graph HGNC:19237 biolink:NamedThing Graph HGNC:19261 biolink:NamedThing Graph HGNC:19263 biolink:NamedThing Graph HGNC:19286 biolink:NamedThing Graph HGNC:19309 biolink:NamedThing Graph HGNC:19316 biolink:NamedThing Graph HGNC:19317 biolink:NamedThing Graph HGNC:1932 biolink:NamedThing Graph HGNC:19321 biolink:NamedThing Graph HGNC:19331 biolink:NamedThing Graph HGNC:19344 biolink:NamedThing Graph HGNC:19349 biolink:NamedThing Graph HGNC:19351 biolink:NamedThing Graph HGNC:19353 biolink:NamedThing Graph HGNC:19358 biolink:NamedThing Graph HGNC:19368 biolink:NamedThing Graph HGNC:1938 biolink:NamedThing Graph HGNC:19380 biolink:NamedThing Graph HGNC:1940 biolink:NamedThing Graph HGNC:19412 biolink:NamedThing Graph HGNC:19414 biolink:NamedThing Graph HGNC:1943 biolink:NamedThing Graph HGNC:19439 biolink:NamedThing Graph HGNC:19440 biolink:NamedThing Graph HGNC:195 biolink:NamedThing Graph HGNC:1952 biolink:NamedThing Graph HGNC:1955 biolink:NamedThing Graph HGNC:1956 biolink:NamedThing Graph HGNC:1958 biolink:NamedThing Graph HGNC:1961 biolink:NamedThing Graph HGNC:1962 biolink:NamedThing Graph HGNC:1965 biolink:NamedThing Graph HGNC:1966 biolink:NamedThing Graph HGNC:19661 biolink:NamedThing Graph HGNC:1967 biolink:NamedThing Graph HGNC:1968 biolink:NamedThing Graph HGNC:19687 biolink:NamedThing Graph HGNC:19688 biolink:NamedThing Graph HGNC:19689 biolink:NamedThing Graph HGNC:19691 biolink:NamedThing Graph HGNC:19693 biolink:NamedThing Graph HGNC:19698 biolink:NamedThing Graph HGNC:19706 biolink:NamedThing Graph HGNC:1971 biolink:NamedThing Graph HGNC:19714 biolink:NamedThing Graph HGNC:19721 biolink:NamedThing Graph HGNC:1974 biolink:NamedThing Graph HGNC:19743 biolink:NamedThing Graph HGNC:1975 biolink:NamedThing Graph HGNC:19750 biolink:NamedThing Graph HGNC:1983 biolink:NamedThing Graph HGNC:1984 biolink:NamedThing Graph HGNC:1985 biolink:NamedThing Graph HGNC:19857 biolink:NamedThing Graph HGNC:19869 biolink:NamedThing Graph HGNC:1987 biolink:NamedThing Graph HGNC:19877 biolink:NamedThing Graph HGNC:19954 biolink:NamedThing Graph HGNC:19957 biolink:NamedThing Graph HGNC:19960 biolink:NamedThing Graph HGNC:19963 biolink:NamedThing Graph HGNC:19967 biolink:NamedThing Graph HGNC:19977 biolink:NamedThing Graph HGNC:19986 biolink:NamedThing Graph HGNC:20 biolink:NamedThing Graph HGNC:20001 biolink:NamedThing Graph HGNC:20041 biolink:NamedThing Graph HGNC:20087 biolink:NamedThing Graph HGNC:20093 biolink:NamedThing Graph HGNC:20105 biolink:NamedThing Graph HGNC:20134 biolink:NamedThing Graph HGNC:20145 biolink:NamedThing Graph HGNC:20151 biolink:NamedThing Graph HGNC:20153 biolink:NamedThing Graph HGNC:20188 biolink:NamedThing Graph HGNC:2019 biolink:NamedThing Graph HGNC:20193 biolink:NamedThing Graph HGNC:20194 biolink:NamedThing Graph HGNC:20197 biolink:NamedThing Graph HGNC:2020 biolink:NamedThing Graph HGNC:20202 biolink:NamedThing Graph HGNC:20207 biolink:NamedThing Graph HGNC:2022 biolink:NamedThing Graph HGNC:2023 biolink:NamedThing Graph HGNC:20233 biolink:NamedThing Graph HGNC:20249 biolink:NamedThing Graph HGNC:2025 biolink:NamedThing Graph HGNC:2027 biolink:NamedThing Graph HGNC:20278 biolink:NamedThing Graph HGNC:20297 biolink:NamedThing Graph HGNC:20305 biolink:NamedThing Graph HGNC:20311 biolink:NamedThing Graph HGNC:20318 biolink:NamedThing Graph HGNC:2032 biolink:NamedThing Graph HGNC:20323 biolink:NamedThing Graph HGNC:20324 biolink:NamedThing Graph HGNC:2033 biolink:NamedThing Graph HGNC:20330 biolink:NamedThing Graph HGNC:20340 biolink:NamedThing Graph HGNC:20342 biolink:NamedThing Graph HGNC:20347 biolink:NamedThing Graph HGNC:2035 biolink:NamedThing Graph HGNC:2037 biolink:NamedThing Graph HGNC:20371 biolink:NamedThing Graph HGNC:20372 biolink:NamedThing Graph HGNC:20373 biolink:NamedThing Graph HGNC:20376 biolink:NamedThing Graph HGNC:2040 biolink:NamedThing Graph HGNC:20406 biolink:NamedThing Graph HGNC:20407 biolink:NamedThing Graph HGNC:20422 biolink:NamedThing Graph HGNC:20423 biolink:NamedThing Graph HGNC:20439 biolink:NamedThing Graph HGNC:20444 biolink:NamedThing Graph HGNC:20456 biolink:NamedThing Graph HGNC:20473 biolink:NamedThing Graph HGNC:20499 biolink:NamedThing Graph HGNC:20502 biolink:NamedThing Graph HGNC:20509 biolink:NamedThing Graph HGNC:20577 biolink:NamedThing Graph HGNC:20580 biolink:NamedThing Graph HGNC:20581 biolink:NamedThing Graph HGNC:20582 biolink:NamedThing Graph HGNC:20603 biolink:NamedThing Graph HGNC:20626 biolink:NamedThing Graph HGNC:2063 biolink:NamedThing Graph HGNC:20653 biolink:NamedThing Graph HGNC:20661 biolink:NamedThing Graph HGNC:20665 biolink:NamedThing Graph HGNC:20670 biolink:NamedThing Graph HGNC:20672 biolink:NamedThing Graph HGNC:20692 biolink:NamedThing Graph HGNC:20716 biolink:NamedThing Graph HGNC:2073 biolink:NamedThing Graph HGNC:20731 biolink:NamedThing Graph HGNC:2074 biolink:NamedThing Graph HGNC:20748 biolink:NamedThing Graph HGNC:2076 biolink:NamedThing Graph HGNC:20761 biolink:NamedThing Graph HGNC:20766 biolink:NamedThing Graph HGNC:2077 biolink:NamedThing Graph HGNC:20772 biolink:NamedThing Graph HGNC:20773 biolink:NamedThing Graph HGNC:20778 biolink:NamedThing Graph HGNC:20788 biolink:NamedThing Graph HGNC:2079 biolink:NamedThing Graph HGNC:20800 biolink:NamedThing Graph HGNC:2084 biolink:NamedThing Graph HGNC:20856 biolink:NamedThing Graph HGNC:20858 biolink:NamedThing Graph HGNC:20859 biolink:NamedThing Graph HGNC:20862 biolink:NamedThing Graph HGNC:20889 biolink:NamedThing Graph HGNC:20893 biolink:NamedThing Graph HGNC:20914 biolink:NamedThing Graph HGNC:20997 biolink:NamedThing Graph HGNC:21014 biolink:NamedThing Graph HGNC:21022 biolink:NamedThing Graph HGNC:21024 biolink:NamedThing Graph HGNC:21033 biolink:NamedThing Graph HGNC:21034 biolink:NamedThing Graph HGNC:21042 biolink:NamedThing Graph HGNC:21043 biolink:NamedThing Graph HGNC:21054 biolink:NamedThing Graph HGNC:21056 biolink:NamedThing Graph HGNC:21057 biolink:NamedThing Graph HGNC:21061 biolink:NamedThing Graph HGNC:21062 biolink:NamedThing Graph HGNC:21071 biolink:NamedThing Graph HGNC:21082 biolink:NamedThing Graph HGNC:21086 biolink:NamedThing Graph HGNC:21143 biolink:NamedThing Graph HGNC:21144 biolink:NamedThing Graph HGNC:21150 biolink:NamedThing Graph HGNC:21157 biolink:NamedThing Graph HGNC:21176 biolink:NamedThing Graph HGNC:21181 biolink:NamedThing Graph HGNC:21197 biolink:NamedThing Graph HGNC:21219 biolink:NamedThing Graph HGNC:21237 biolink:NamedThing Graph HGNC:21244 biolink:NamedThing Graph HGNC:21246 biolink:NamedThing Graph HGNC:21253 biolink:NamedThing Graph HGNC:21285 biolink:NamedThing Graph HGNC:21304 biolink:NamedThing Graph HGNC:21307 biolink:NamedThing Graph HGNC:21308 biolink:NamedThing Graph HGNC:21316 biolink:NamedThing Graph HGNC:21317 biolink:NamedThing Graph HGNC:2135 biolink:NamedThing Graph HGNC:21350 biolink:NamedThing Graph HGNC:21365 biolink:NamedThing Graph HGNC:21390 biolink:NamedThing Graph HGNC:21396 biolink:NamedThing Graph HGNC:21406 biolink:NamedThing Graph HGNC:21424 biolink:NamedThing Graph HGNC:21474 biolink:NamedThing Graph HGNC:21478 biolink:NamedThing Graph HGNC:2148 biolink:NamedThing Graph HGNC:21484 biolink:NamedThing Graph HGNC:21493 biolink:NamedThing Graph HGNC:21497 biolink:NamedThing Graph HGNC:21498 biolink:NamedThing Graph HGNC:2150 biolink:NamedThing Graph HGNC:2151 biolink:NamedThing Graph HGNC:21528 biolink:NamedThing Graph HGNC:2153 biolink:NamedThing Graph HGNC:21555 biolink:NamedThing Graph HGNC:21558 biolink:NamedThing Graph HGNC:21575 biolink:NamedThing Graph HGNC:21580 biolink:NamedThing Graph HGNC:216 biolink:NamedThing Graph HGNC:21606 biolink:NamedThing Graph HGNC:21637 biolink:NamedThing Graph HGNC:21641 biolink:NamedThing Graph HGNC:21642 biolink:NamedThing Graph HGNC:21645 biolink:NamedThing Graph HGNC:21652 biolink:NamedThing Graph HGNC:21653 biolink:NamedThing Graph HGNC:21679 biolink:NamedThing Graph HGNC:21686 biolink:NamedThing Graph HGNC:21694 biolink:NamedThing Graph HGNC:21698 biolink:NamedThing Graph HGNC:21699 biolink:NamedThing Graph HGNC:21701 biolink:NamedThing Graph HGNC:21708 biolink:NamedThing Graph HGNC:2171 biolink:NamedThing Graph HGNC:2172 biolink:NamedThing Graph HGNC:21732 biolink:NamedThing Graph HGNC:21734 biolink:NamedThing Graph HGNC:218 biolink:NamedThing Graph HGNC:2180 biolink:NamedThing Graph HGNC:2183 biolink:NamedThing Graph HGNC:2185 biolink:NamedThing Graph HGNC:2186 biolink:NamedThing Graph HGNC:21862 biolink:NamedThing Graph HGNC:21863 biolink:NamedThing Graph HGNC:21869 biolink:NamedThing Graph HGNC:2187 biolink:NamedThing Graph HGNC:2188 biolink:NamedThing Graph HGNC:2190 biolink:NamedThing Graph HGNC:2194 biolink:NamedThing Graph HGNC:2195 biolink:NamedThing Graph HGNC:21957 biolink:NamedThing Graph HGNC:2197 biolink:NamedThing Graph HGNC:2198 biolink:NamedThing Graph HGNC:2200 biolink:NamedThing Graph HGNC:2201 biolink:NamedThing Graph HGNC:2202 biolink:NamedThing Graph HGNC:2203 biolink:NamedThing Graph HGNC:2204 biolink:NamedThing Graph HGNC:2205 biolink:NamedThing Graph HGNC:2207 biolink:NamedThing Graph HGNC:2208 biolink:NamedThing Graph HGNC:22082 biolink:NamedThing Graph HGNC:2209 biolink:NamedThing Graph HGNC:2210 biolink:NamedThing Graph HGNC:2212 biolink:NamedThing Graph HGNC:2213 biolink:NamedThing Graph HGNC:2214 biolink:NamedThing Graph HGNC:22140 biolink:NamedThing Graph HGNC:2216 biolink:NamedThing Graph HGNC:2217 biolink:NamedThing Graph HGNC:2218 biolink:NamedThing Graph HGNC:2219 biolink:NamedThing Graph HGNC:22197 biolink:NamedThing Graph HGNC:2220 biolink:NamedThing Graph HGNC:2226 biolink:NamedThing Graph HGNC:2227 biolink:NamedThing Graph HGNC:2228 biolink:NamedThing Graph HGNC:2230 biolink:NamedThing Graph HGNC:2244 biolink:NamedThing Graph HGNC:22448 biolink:NamedThing Graph HGNC:225 biolink:NamedThing Graph HGNC:2252 biolink:NamedThing Graph HGNC:2263 biolink:NamedThing Graph HGNC:2277 biolink:NamedThing Graph HGNC:22788 biolink:NamedThing Graph HGNC:2291 biolink:NamedThing Graph HGNC:22923 biolink:NamedThing Graph HGNC:22932 biolink:NamedThing Graph HGNC:22938 biolink:NamedThing Graph HGNC:22947 biolink:NamedThing Graph HGNC:2295 biolink:NamedThing Graph HGNC:22954 biolink:NamedThing Graph HGNC:22962 biolink:NamedThing Graph HGNC:22965 biolink:NamedThing Graph HGNC:22986 biolink:NamedThing Graph HGNC:23 biolink:NamedThing Graph HGNC:23015 biolink:NamedThing Graph HGNC:23026 biolink:NamedThing Graph HGNC:23038 biolink:NamedThing Graph HGNC:23041 biolink:NamedThing Graph HGNC:23044 biolink:NamedThing Graph HGNC:23056 biolink:NamedThing Graph HGNC:23068 biolink:NamedThing Graph HGNC:23088 biolink:NamedThing Graph HGNC:23089 biolink:NamedThing Graph HGNC:23094 biolink:NamedThing Graph HGNC:23096 biolink:NamedThing Graph HGNC:23109 biolink:NamedThing Graph HGNC:2312 biolink:NamedThing Graph HGNC:23141 biolink:NamedThing Graph HGNC:23143 biolink:NamedThing Graph HGNC:23147 biolink:NamedThing Graph HGNC:23151 biolink:NamedThing Graph HGNC:23157 biolink:NamedThing Graph HGNC:23159 biolink:NamedThing Graph HGNC:23161 biolink:NamedThing Graph HGNC:23166 biolink:NamedThing Graph HGNC:23198 biolink:NamedThing Graph HGNC:232 biolink:NamedThing Graph HGNC:23204 biolink:NamedThing Graph HGNC:2321 biolink:NamedThing Graph HGNC:23212 biolink:NamedThing Graph HGNC:23213 biolink:NamedThing Graph HGNC:23215 biolink:NamedThing Graph HGNC:23216 biolink:NamedThing Graph HGNC:23228 biolink:NamedThing Graph HGNC:2323 biolink:NamedThing Graph HGNC:23230 biolink:NamedThing Graph HGNC:23246 biolink:NamedThing Graph HGNC:23247 biolink:NamedThing Graph HGNC:2328 biolink:NamedThing Graph HGNC:23287 biolink:NamedThing Graph HGNC:2330 biolink:NamedThing Graph HGNC:23338 biolink:NamedThing Graph HGNC:2336 biolink:NamedThing Graph HGNC:23399 biolink:NamedThing Graph HGNC:2340 biolink:NamedThing Graph HGNC:23405 biolink:NamedThing Graph HGNC:23406 biolink:NamedThing Graph HGNC:23419 biolink:NamedThing Graph HGNC:2343 biolink:NamedThing Graph HGNC:2345 biolink:NamedThing Graph HGNC:23452 biolink:NamedThing Graph HGNC:2348 biolink:NamedThing Graph HGNC:23503 biolink:NamedThing Graph HGNC:23505 biolink:NamedThing Graph HGNC:23508 biolink:NamedThing Graph HGNC:23537 biolink:NamedThing Graph HGNC:23564 biolink:NamedThing Graph HGNC:23573 biolink:NamedThing Graph HGNC:23594 biolink:NamedThing Graph HGNC:236 biolink:NamedThing Graph HGNC:23631 biolink:NamedThing Graph HGNC:23639 biolink:NamedThing Graph HGNC:2364 biolink:NamedThing Graph HGNC:23657 biolink:NamedThing Graph HGNC:23663 biolink:NamedThing Graph HGNC:237 biolink:NamedThing Graph HGNC:23719 biolink:NamedThing Graph HGNC:2372 biolink:NamedThing Graph HGNC:23734 biolink:NamedThing Graph HGNC:2375 biolink:NamedThing Graph HGNC:23752 biolink:NamedThing Graph HGNC:23785 biolink:NamedThing Graph HGNC:2379 biolink:NamedThing Graph HGNC:23791 biolink:NamedThing Graph HGNC:23801 biolink:NamedThing Graph HGNC:23805 biolink:NamedThing Graph HGNC:2383 biolink:NamedThing Graph HGNC:2384 biolink:NamedThing Graph HGNC:23845 biolink:NamedThing Graph HGNC:2388 biolink:NamedThing Graph HGNC:2389 biolink:NamedThing Graph HGNC:2394 biolink:NamedThing Graph HGNC:2395 biolink:NamedThing Graph HGNC:2396 biolink:NamedThing Graph HGNC:2397 biolink:NamedThing Graph HGNC:2398 biolink:NamedThing Graph HGNC:23987 biolink:NamedThing Graph HGNC:2400 biolink:NamedThing Graph HGNC:24035 biolink:NamedThing Graph HGNC:24036 biolink:NamedThing Graph HGNC:24039 biolink:NamedThing Graph HGNC:24054 biolink:NamedThing Graph HGNC:2409 biolink:NamedThing Graph HGNC:2410 biolink:NamedThing Graph HGNC:2411 biolink:NamedThing Graph HGNC:24116 biolink:NamedThing Graph HGNC:24123 biolink:NamedThing Graph HGNC:24124 biolink:NamedThing Graph HGNC:24154 biolink:NamedThing Graph HGNC:24160 biolink:NamedThing Graph HGNC:2417 biolink:NamedThing Graph HGNC:2418 biolink:NamedThing Graph HGNC:24200 biolink:NamedThing Graph HGNC:24212 biolink:NamedThing Graph HGNC:24229 biolink:NamedThing Graph HGNC:24245 biolink:NamedThing Graph HGNC:24247 biolink:NamedThing Graph HGNC:24249 biolink:NamedThing Graph HGNC:24265 biolink:NamedThing Graph HGNC:24268 biolink:NamedThing Graph HGNC:24270 biolink:NamedThing Graph HGNC:2433 biolink:NamedThing Graph HGNC:24338 biolink:NamedThing Graph HGNC:2436 biolink:NamedThing Graph HGNC:2439 biolink:NamedThing Graph HGNC:24415 biolink:NamedThing Graph HGNC:24431 biolink:NamedThing Graph HGNC:24464 biolink:NamedThing Graph HGNC:24475 biolink:NamedThing Graph HGNC:24488 biolink:NamedThing Graph HGNC:245 biolink:NamedThing Graph HGNC:24502 biolink:NamedThing Graph HGNC:24519 biolink:NamedThing Graph HGNC:2452 biolink:NamedThing Graph HGNC:24525 biolink:NamedThing Graph HGNC:24526 biolink:NamedThing Graph HGNC:24529 biolink:NamedThing Graph HGNC:24537 biolink:NamedThing Graph HGNC:24539 biolink:NamedThing Graph HGNC:24564 biolink:NamedThing Graph HGNC:24565 biolink:NamedThing Graph HGNC:2457 biolink:NamedThing Graph HGNC:24576 biolink:NamedThing Graph HGNC:24579 biolink:NamedThing Graph HGNC:24587 biolink:NamedThing Graph HGNC:24592 biolink:NamedThing Graph HGNC:24595 biolink:NamedThing Graph HGNC:24624 biolink:NamedThing Graph HGNC:2464 biolink:NamedThing Graph HGNC:24650 biolink:NamedThing Graph HGNC:24668 biolink:NamedThing Graph HGNC:24669 biolink:NamedThing Graph HGNC:24671 biolink:NamedThing Graph HGNC:24678 biolink:NamedThing Graph HGNC:2468 biolink:NamedThing Graph HGNC:24682 biolink:NamedThing Graph HGNC:24717 biolink:NamedThing Graph HGNC:2472 biolink:NamedThing Graph HGNC:24725 biolink:NamedThing Graph HGNC:2475 biolink:NamedThing Graph HGNC:24783 biolink:NamedThing Graph HGNC:24797 biolink:NamedThing Graph HGNC:2481 biolink:NamedThing Graph HGNC:2482 biolink:NamedThing Graph HGNC:24858 biolink:NamedThing Graph HGNC:24861 biolink:NamedThing Graph HGNC:24862 biolink:NamedThing Graph HGNC:24866 biolink:NamedThing Graph HGNC:2488 biolink:NamedThing Graph HGNC:24891 biolink:NamedThing Graph HGNC:24912 biolink:NamedThing Graph HGNC:24928 biolink:NamedThing Graph HGNC:24945 biolink:NamedThing Graph HGNC:24969 biolink:NamedThing Graph HGNC:2498 biolink:NamedThing Graph HGNC:25009 biolink:NamedThing Graph HGNC:2501 biolink:NamedThing Graph HGNC:25018 biolink:NamedThing Graph HGNC:25033 biolink:NamedThing Graph HGNC:2505 biolink:NamedThing Graph HGNC:25070 biolink:NamedThing Graph HGNC:25088 biolink:NamedThing Graph HGNC:2509 biolink:NamedThing Graph HGNC:2511 biolink:NamedThing Graph HGNC:25118 biolink:NamedThing Graph HGNC:25133 biolink:NamedThing Graph HGNC:25135 biolink:NamedThing Graph HGNC:2514 biolink:NamedThing Graph HGNC:2515 biolink:NamedThing Graph HGNC:25151 biolink:NamedThing Graph HGNC:25155 biolink:NamedThing Graph HGNC:2518 biolink:NamedThing Graph HGNC:25186 biolink:NamedThing Graph HGNC:2519 biolink:NamedThing Graph HGNC:25198 biolink:NamedThing Graph HGNC:25221 biolink:NamedThing Graph HGNC:25223 biolink:NamedThing Graph HGNC:25230 biolink:NamedThing Graph HGNC:25240 biolink:NamedThing Graph HGNC:25244 biolink:NamedThing Graph HGNC:2528 biolink:NamedThing Graph HGNC:25280 biolink:NamedThing Graph HGNC:2529 biolink:NamedThing Graph HGNC:25302 biolink:NamedThing Graph HGNC:2531 biolink:NamedThing Graph HGNC:25355 biolink:NamedThing Graph HGNC:25356 biolink:NamedThing Graph HGNC:25358 biolink:NamedThing Graph HGNC:2536 biolink:NamedThing Graph HGNC:25360 biolink:NamedThing Graph HGNC:25367 biolink:NamedThing Graph HGNC:25382 biolink:NamedThing Graph HGNC:25403 biolink:NamedThing Graph HGNC:25415 biolink:NamedThing Graph HGNC:25419 biolink:NamedThing Graph HGNC:25439 biolink:NamedThing Graph HGNC:25443 biolink:NamedThing Graph HGNC:25455 biolink:NamedThing Graph HGNC:25461 biolink:NamedThing Graph HGNC:2548 biolink:NamedThing Graph HGNC:25481 biolink:NamedThing Graph HGNC:25491 biolink:NamedThing Graph HGNC:25507 biolink:NamedThing Graph HGNC:25519 biolink:NamedThing Graph HGNC:25522 biolink:NamedThing Graph HGNC:25523 biolink:NamedThing Graph HGNC:2553 biolink:NamedThing Graph HGNC:25532 biolink:NamedThing Graph HGNC:25535 biolink:NamedThing Graph HGNC:25538 biolink:NamedThing Graph HGNC:2555 biolink:NamedThing Graph HGNC:25557 biolink:NamedThing Graph HGNC:25566 biolink:NamedThing Graph HGNC:25567 biolink:NamedThing Graph HGNC:25568 biolink:NamedThing Graph HGNC:25576 biolink:NamedThing Graph HGNC:2558 biolink:NamedThing Graph HGNC:25583 biolink:NamedThing Graph HGNC:25608 biolink:NamedThing Graph HGNC:2561 biolink:NamedThing Graph HGNC:25613 biolink:NamedThing Graph HGNC:25640 biolink:NamedThing Graph HGNC:25660 biolink:NamedThing Graph HGNC:25662 biolink:NamedThing Graph HGNC:2567 biolink:NamedThing Graph HGNC:25671 biolink:NamedThing Graph HGNC:25676 biolink:NamedThing Graph HGNC:2568 biolink:NamedThing Graph HGNC:25695 biolink:NamedThing Graph HGNC:257 biolink:NamedThing Graph HGNC:2570 biolink:NamedThing Graph HGNC:25705 biolink:NamedThing Graph HGNC:25712 biolink:NamedThing Graph HGNC:25726 biolink:NamedThing Graph HGNC:25737 biolink:NamedThing Graph HGNC:25740 biolink:NamedThing Graph HGNC:25751 biolink:NamedThing Graph HGNC:25763 biolink:NamedThing Graph HGNC:2577 biolink:NamedThing Graph HGNC:25774 biolink:NamedThing Graph HGNC:2578 biolink:NamedThing Graph HGNC:25781 biolink:NamedThing Graph HGNC:25784 biolink:NamedThing Graph HGNC:25786 biolink:NamedThing Graph HGNC:2579 biolink:NamedThing Graph HGNC:25792 biolink:NamedThing Graph HGNC:25799 biolink:NamedThing Graph HGNC:25801 biolink:NamedThing Graph HGNC:25808 biolink:NamedThing Graph HGNC:25812 biolink:NamedThing Graph HGNC:25815 biolink:NamedThing Graph HGNC:25839 biolink:NamedThing Graph HGNC:2584 biolink:NamedThing Graph HGNC:25843 biolink:NamedThing Graph HGNC:25896 biolink:NamedThing Graph HGNC:25897 biolink:NamedThing Graph HGNC:2590 biolink:NamedThing Graph HGNC:25902 biolink:NamedThing Graph HGNC:2591 biolink:NamedThing Graph HGNC:2592 biolink:NamedThing Graph HGNC:2593 biolink:NamedThing Graph HGNC:2594 biolink:NamedThing Graph HGNC:25947 biolink:NamedThing Graph HGNC:25964 biolink:NamedThing Graph HGNC:2597 biolink:NamedThing Graph HGNC:25985 biolink:NamedThing Graph HGNC:25994 biolink:NamedThing Graph HGNC:2600 biolink:NamedThing Graph HGNC:26006 biolink:NamedThing Graph HGNC:26013 biolink:NamedThing Graph HGNC:26019 biolink:NamedThing Graph HGNC:2602 biolink:NamedThing Graph HGNC:26022 biolink:NamedThing Graph HGNC:26031 biolink:NamedThing Graph HGNC:26034 biolink:NamedThing Graph HGNC:2605 biolink:NamedThing Graph HGNC:26050 biolink:NamedThing Graph HGNC:26054 biolink:NamedThing Graph HGNC:2606 biolink:NamedThing Graph HGNC:26090 biolink:NamedThing Graph HGNC:26113 biolink:NamedThing Graph HGNC:26114 biolink:NamedThing Graph HGNC:26144 biolink:NamedThing Graph HGNC:26147 biolink:NamedThing Graph HGNC:26158 biolink:NamedThing Graph HGNC:26162 biolink:NamedThing Graph HGNC:26169 biolink:NamedThing Graph HGNC:26182 biolink:NamedThing Graph HGNC:26193 biolink:NamedThing Graph HGNC:26200 biolink:NamedThing Graph HGNC:26222 biolink:NamedThing Graph HGNC:26230 biolink:NamedThing Graph HGNC:26262 biolink:NamedThing Graph HGNC:26267 biolink:NamedThing Graph HGNC:26270 biolink:NamedThing Graph HGNC:26274 biolink:NamedThing Graph HGNC:26291 biolink:NamedThing Graph HGNC:26300 biolink:NamedThing Graph HGNC:26348 biolink:NamedThing Graph HGNC:26361 biolink:NamedThing Graph HGNC:26401 biolink:NamedThing Graph HGNC:26404 biolink:NamedThing Graph HGNC:26444 biolink:NamedThing Graph HGNC:2649 biolink:NamedThing Graph HGNC:26498 biolink:NamedThing Graph HGNC:26504 biolink:NamedThing Graph HGNC:26513 biolink:NamedThing Graph HGNC:2652 biolink:NamedThing Graph HGNC:26521 biolink:NamedThing Graph HGNC:26527 biolink:NamedThing Graph HGNC:26530 biolink:NamedThing Graph HGNC:26551 biolink:NamedThing Graph HGNC:26558 biolink:NamedThing Graph HGNC:26559 biolink:NamedThing Graph HGNC:26560 biolink:NamedThing Graph HGNC:26575 biolink:NamedThing Graph HGNC:26576 biolink:NamedThing Graph HGNC:26582 biolink:NamedThing Graph HGNC:26594 biolink:NamedThing Graph HGNC:26600 biolink:NamedThing Graph HGNC:2661 biolink:NamedThing Graph HGNC:26624 biolink:NamedThing Graph HGNC:26648 biolink:NamedThing Graph HGNC:2665 biolink:NamedThing Graph HGNC:2666 biolink:NamedThing Graph HGNC:26661 biolink:NamedThing Graph HGNC:26690 biolink:NamedThing Graph HGNC:26703 biolink:NamedThing Graph HGNC:26724 biolink:NamedThing Graph HGNC:26742 biolink:NamedThing Graph HGNC:2678 biolink:NamedThing Graph HGNC:26784 biolink:NamedThing Graph HGNC:26790 biolink:NamedThing Graph HGNC:2682 biolink:NamedThing Graph HGNC:26837 biolink:NamedThing Graph HGNC:26877 biolink:NamedThing Graph HGNC:26887 biolink:NamedThing Graph HGNC:2689 biolink:NamedThing Graph HGNC:26894 biolink:NamedThing Graph HGNC:26899 biolink:NamedThing Graph HGNC:26901 biolink:NamedThing Graph HGNC:26922 biolink:NamedThing Graph HGNC:26926 biolink:NamedThing Graph HGNC:26927 biolink:NamedThing Graph HGNC:26929 biolink:NamedThing Graph HGNC:26938 biolink:NamedThing Graph HGNC:26944 biolink:NamedThing Graph HGNC:2698 biolink:NamedThing Graph HGNC:26988 biolink:NamedThing Graph HGNC:2701 biolink:NamedThing Graph HGNC:27030 biolink:NamedThing Graph HGNC:2705 biolink:NamedThing Graph HGNC:2707 biolink:NamedThing Graph HGNC:27089 biolink:NamedThing Graph HGNC:2711 biolink:NamedThing Graph HGNC:2714 biolink:NamedThing Graph HGNC:2718 biolink:NamedThing Graph HGNC:2719 biolink:NamedThing Graph HGNC:27230 biolink:NamedThing Graph HGNC:27232 biolink:NamedThing Graph HGNC:2726 biolink:NamedThing Graph HGNC:2728 biolink:NamedThing Graph HGNC:27288 biolink:NamedThing Graph HGNC:27302 biolink:NamedThing Graph HGNC:2731 biolink:NamedThing Graph HGNC:27310 biolink:NamedThing Graph HGNC:27337 biolink:NamedThing Graph HGNC:2736 biolink:NamedThing Graph HGNC:27365 biolink:NamedThing Graph HGNC:27375 biolink:NamedThing Graph HGNC:27424 biolink:NamedThing Graph HGNC:2745 biolink:NamedThing Graph HGNC:27561 biolink:NamedThing Graph HGNC:2770 biolink:NamedThing Graph HGNC:2771 biolink:NamedThing Graph HGNC:27960 biolink:NamedThing Graph HGNC:27962 biolink:NamedThing Graph HGNC:2799 biolink:NamedThing Graph HGNC:28018 biolink:NamedThing Graph HGNC:28027 biolink:NamedThing Graph HGNC:28033 biolink:NamedThing Graph HGNC:28052 biolink:NamedThing Graph HGNC:28072 biolink:NamedThing Graph HGNC:28086 biolink:NamedThing Graph HGNC:28093 biolink:NamedThing Graph HGNC:2810 biolink:NamedThing Graph HGNC:28178 biolink:NamedThing Graph HGNC:282 biolink:NamedThing Graph HGNC:28209 biolink:NamedThing Graph HGNC:28213 biolink:NamedThing Graph HGNC:28249 biolink:NamedThing Graph HGNC:28261 biolink:NamedThing Graph HGNC:28287 biolink:NamedThing Graph HGNC:28296 biolink:NamedThing Graph HGNC:28303 biolink:NamedThing Graph HGNC:28337 biolink:NamedThing Graph HGNC:28358 biolink:NamedThing Graph HGNC:28369 biolink:NamedThing Graph HGNC:28385 biolink:NamedThing Graph HGNC:28396 biolink:NamedThing Graph HGNC:28403 biolink:NamedThing Graph HGNC:28422 biolink:NamedThing Graph HGNC:28423 biolink:NamedThing Graph HGNC:2843 biolink:NamedThing Graph HGNC:28434 biolink:NamedThing Graph HGNC:28472 biolink:NamedThing Graph HGNC:28486 biolink:NamedThing Graph HGNC:28510 biolink:NamedThing Graph HGNC:28514 biolink:NamedThing Graph HGNC:2852 biolink:NamedThing Graph HGNC:28526 biolink:NamedThing Graph HGNC:28557 biolink:NamedThing Graph HGNC:28570 biolink:NamedThing Graph HGNC:2858 biolink:NamedThing Graph HGNC:2859 biolink:NamedThing Graph HGNC:28596 biolink:NamedThing Graph HGNC:2860 biolink:NamedThing Graph HGNC:2861 biolink:NamedThing Graph HGNC:28625 biolink:NamedThing Graph HGNC:28636 biolink:NamedThing Graph HGNC:28648 biolink:NamedThing Graph HGNC:2865 biolink:NamedThing Graph HGNC:2867 biolink:NamedThing Graph HGNC:28722 biolink:NamedThing Graph HGNC:28727 biolink:NamedThing Graph HGNC:2873 biolink:NamedThing Graph HGNC:28741 biolink:NamedThing Graph HGNC:2876 biolink:NamedThing Graph HGNC:28769 biolink:NamedThing Graph HGNC:2877 biolink:NamedThing Graph HGNC:28844 biolink:NamedThing Graph HGNC:28845 biolink:NamedThing Graph HGNC:28852 biolink:NamedThing Graph HGNC:28862 biolink:NamedThing Graph HGNC:2888 biolink:NamedThing Graph HGNC:28880 biolink:NamedThing Graph HGNC:28883 biolink:NamedThing Graph HGNC:28887 biolink:NamedThing Graph HGNC:2890 biolink:NamedThing Graph HGNC:28900 biolink:NamedThing Graph HGNC:28908 biolink:NamedThing Graph HGNC:28909 biolink:NamedThing Graph HGNC:28912 biolink:NamedThing Graph HGNC:28927 biolink:NamedThing Graph HGNC:28929 biolink:NamedThing Graph HGNC:28949 biolink:NamedThing Graph HGNC:28956 biolink:NamedThing Graph HGNC:28957 biolink:NamedThing Graph HGNC:28958 biolink:NamedThing Graph HGNC:2896 biolink:NamedThing Graph HGNC:2898 biolink:NamedThing Graph HGNC:28984 biolink:NamedThing Graph HGNC:28991 biolink:NamedThing Graph HGNC:28993 biolink:NamedThing Graph HGNC:29 biolink:NamedThing Graph HGNC:29007 biolink:NamedThing Graph HGNC:29017 biolink:NamedThing Graph HGNC:2902 biolink:NamedThing Graph HGNC:29021 biolink:NamedThing Graph HGNC:29022 biolink:NamedThing Graph HGNC:29040 biolink:NamedThing Graph HGNC:29043 biolink:NamedThing Graph HGNC:29059 biolink:NamedThing Graph HGNC:29068 biolink:NamedThing Graph HGNC:29077 biolink:NamedThing Graph HGNC:29079 biolink:NamedThing Graph HGNC:29086 biolink:NamedThing Graph HGNC:2909 biolink:NamedThing Graph HGNC:29090 biolink:NamedThing Graph HGNC:29092 biolink:NamedThing Graph HGNC:29099 biolink:NamedThing Graph HGNC:291 biolink:NamedThing Graph HGNC:2910 biolink:NamedThing Graph HGNC:29101 biolink:NamedThing Graph HGNC:29105 biolink:NamedThing Graph HGNC:29106 biolink:NamedThing Graph HGNC:29110 biolink:NamedThing Graph HGNC:29144 biolink:NamedThing Graph HGNC:2916 biolink:NamedThing Graph HGNC:29168 biolink:NamedThing Graph HGNC:2917 biolink:NamedThing Graph HGNC:29170 biolink:NamedThing Graph HGNC:29174 biolink:NamedThing Graph HGNC:2918 biolink:NamedThing Graph HGNC:29182 biolink:NamedThing Graph HGNC:29203 biolink:NamedThing Graph HGNC:29205 biolink:NamedThing Graph HGNC:29215 biolink:NamedThing Graph HGNC:29216 biolink:NamedThing Graph HGNC:29222 biolink:NamedThing Graph HGNC:29242 biolink:NamedThing Graph HGNC:29250 biolink:NamedThing Graph HGNC:29253 biolink:NamedThing Graph HGNC:29256 biolink:NamedThing Graph HGNC:29262 biolink:NamedThing Graph HGNC:29277 biolink:NamedThing Graph HGNC:2928 biolink:NamedThing Graph HGNC:29284 biolink:NamedThing Graph HGNC:29298 biolink:NamedThing Graph HGNC:29300 biolink:NamedThing Graph HGNC:29304 biolink:NamedThing Graph HGNC:29316 biolink:NamedThing Graph HGNC:2932 biolink:NamedThing Graph HGNC:29326 biolink:NamedThing Graph HGNC:2933 biolink:NamedThing Graph HGNC:29331 biolink:NamedThing Graph HGNC:29347 biolink:NamedThing Graph HGNC:29357 biolink:NamedThing Graph HGNC:2938 biolink:NamedThing Graph HGNC:2939 biolink:NamedThing Graph HGNC:29401 biolink:NamedThing Graph HGNC:29418 biolink:NamedThing Graph HGNC:29419 biolink:NamedThing Graph HGNC:2942 biolink:NamedThing Graph HGNC:29420 biolink:NamedThing Graph HGNC:29426 biolink:NamedThing Graph HGNC:29427 biolink:NamedThing Graph HGNC:29433 biolink:NamedThing Graph HGNC:29450 biolink:NamedThing Graph HGNC:29456 biolink:NamedThing Graph HGNC:29478 biolink:NamedThing Graph HGNC:2950 biolink:NamedThing Graph HGNC:29501 biolink:NamedThing Graph HGNC:29502 biolink:NamedThing Graph HGNC:29508 biolink:NamedThing Graph HGNC:29514 biolink:NamedThing Graph HGNC:29515 biolink:NamedThing Graph HGNC:29521 biolink:NamedThing Graph HGNC:29529 biolink:NamedThing Graph HGNC:29536 biolink:NamedThing Graph HGNC:2954 biolink:NamedThing Graph HGNC:2955 biolink:NamedThing Graph HGNC:29557 biolink:NamedThing Graph HGNC:29561 biolink:NamedThing Graph HGNC:29569 biolink:NamedThing Graph HGNC:2959 biolink:NamedThing Graph HGNC:29594 biolink:NamedThing Graph HGNC:29597 biolink:NamedThing Graph HGNC:2961 biolink:NamedThing Graph HGNC:29634 biolink:NamedThing Graph HGNC:29643 biolink:NamedThing Graph HGNC:29659 biolink:NamedThing Graph HGNC:29666 biolink:NamedThing Graph HGNC:29669 biolink:NamedThing Graph HGNC:29670 biolink:NamedThing Graph HGNC:29673 biolink:NamedThing Graph HGNC:29679 biolink:NamedThing Graph HGNC:29683 biolink:NamedThing Graph HGNC:29685 biolink:NamedThing Graph HGNC:2972 biolink:NamedThing Graph HGNC:2973 biolink:NamedThing Graph HGNC:2974 biolink:NamedThing Graph HGNC:2976 biolink:NamedThing Graph HGNC:2978 biolink:NamedThing Graph HGNC:2979 biolink:NamedThing Graph HGNC:29796 biolink:NamedThing Graph HGNC:29812 biolink:NamedThing Graph HGNC:29843 biolink:NamedThing Graph HGNC:29853 biolink:NamedThing Graph HGNC:2988 biolink:NamedThing Graph HGNC:29882 biolink:NamedThing Graph HGNC:29914 biolink:NamedThing Graph HGNC:29918 biolink:NamedThing Graph HGNC:2993 biolink:NamedThing Graph HGNC:29932 biolink:NamedThing Graph HGNC:29935 biolink:NamedThing Graph HGNC:29937 biolink:NamedThing Graph HGNC:29941 biolink:NamedThing Graph HGNC:29944 biolink:NamedThing Graph HGNC:29945 biolink:NamedThing Graph HGNC:2995 biolink:NamedThing Graph HGNC:30000 biolink:NamedThing Graph HGNC:3003 biolink:NamedThing Graph HGNC:30032 biolink:NamedThing Graph HGNC:30035 biolink:NamedThing Graph HGNC:3005 biolink:NamedThing Graph HGNC:3006 biolink:NamedThing Graph HGNC:30064 biolink:NamedThing Graph HGNC:3007 biolink:NamedThing Graph HGNC:30074 biolink:NamedThing Graph HGNC:30078 biolink:NamedThing Graph HGNC:3010 biolink:NamedThing Graph HGNC:30100 biolink:NamedThing Graph HGNC:3012 biolink:NamedThing Graph HGNC:3013 biolink:NamedThing Graph HGNC:30171 biolink:NamedThing Graph HGNC:30172 biolink:NamedThing Graph HGNC:3018 biolink:NamedThing Graph HGNC:30185 biolink:NamedThing Graph HGNC:30213 biolink:NamedThing Graph HGNC:30220 biolink:NamedThing Graph HGNC:30224 biolink:NamedThing Graph HGNC:30225 biolink:NamedThing Graph HGNC:30237 biolink:NamedThing Graph HGNC:3024 biolink:NamedThing Graph HGNC:30242 biolink:NamedThing Graph HGNC:3026 biolink:NamedThing Graph HGNC:30260 biolink:NamedThing Graph HGNC:30262 biolink:NamedThing Graph HGNC:303 biolink:NamedThing Graph HGNC:3033 biolink:NamedThing Graph HGNC:30343 biolink:NamedThing Graph HGNC:30348 biolink:NamedThing Graph HGNC:3036 biolink:NamedThing Graph HGNC:30372 biolink:NamedThing Graph HGNC:30391 biolink:NamedThing Graph HGNC:30417 biolink:NamedThing Graph HGNC:3046 biolink:NamedThing Graph HGNC:3048 biolink:NamedThing Graph HGNC:3049 biolink:NamedThing Graph HGNC:30492 biolink:NamedThing Graph HGNC:30497 biolink:NamedThing Graph HGNC:30500 biolink:NamedThing Graph HGNC:3052 biolink:NamedThing Graph HGNC:30521 biolink:NamedThing Graph HGNC:30528 biolink:NamedThing Graph HGNC:30539 biolink:NamedThing Graph HGNC:3054 biolink:NamedThing Graph HGNC:30546 biolink:NamedThing Graph HGNC:30551 biolink:NamedThing Graph HGNC:3057 biolink:NamedThing Graph HGNC:30578 biolink:NamedThing Graph HGNC:30587 biolink:NamedThing Graph HGNC:30605 biolink:NamedThing Graph HGNC:30611 biolink:NamedThing Graph HGNC:30650 biolink:NamedThing Graph HGNC:30664 biolink:NamedThing Graph HGNC:30668 biolink:NamedThing Graph HGNC:30718 biolink:NamedThing Graph HGNC:3072 biolink:NamedThing Graph HGNC:30740 biolink:NamedThing Graph HGNC:30760 biolink:NamedThing Graph HGNC:30764 biolink:NamedThing Graph HGNC:30765 biolink:NamedThing Graph HGNC:30778 biolink:NamedThing Graph HGNC:30791 biolink:NamedThing Graph HGNC:30794 biolink:NamedThing Graph HGNC:30800 biolink:NamedThing Graph HGNC:30802 biolink:NamedThing Graph HGNC:30829 biolink:NamedThing Graph HGNC:30831 biolink:NamedThing Graph HGNC:30832 biolink:NamedThing Graph HGNC:30836 biolink:NamedThing Graph HGNC:30839 biolink:NamedThing Graph HGNC:3084 biolink:NamedThing Graph HGNC:30858 biolink:NamedThing Graph HGNC:30859 biolink:NamedThing Graph HGNC:3087 biolink:NamedThing Graph HGNC:30881 biolink:NamedThing Graph HGNC:30883 biolink:NamedThing Graph HGNC:30892 biolink:NamedThing Graph HGNC:3091 biolink:NamedThing Graph HGNC:3092 biolink:NamedThing Graph HGNC:30922 biolink:NamedThing Graph HGNC:30935 biolink:NamedThing Graph HGNC:30939 biolink:NamedThing Graph HGNC:3097 biolink:NamedThing Graph HGNC:30972 biolink:NamedThing Graph HGNC:3098 biolink:NamedThing Graph HGNC:3133 biolink:NamedThing Graph HGNC:31371 biolink:NamedThing Graph HGNC:31399 biolink:NamedThing Graph HGNC:3146 biolink:NamedThing Graph HGNC:3147 biolink:NamedThing Graph HGNC:315 biolink:NamedThing Graph HGNC:3151 biolink:NamedThing Graph HGNC:3153 biolink:NamedThing Graph HGNC:31555 biolink:NamedThing Graph HGNC:3157 biolink:NamedThing Graph HGNC:31582 biolink:NamedThing Graph HGNC:31648 biolink:NamedThing Graph HGNC:31673 biolink:NamedThing Graph HGNC:3169 biolink:NamedThing Graph HGNC:3176 biolink:NamedThing Graph HGNC:3178 biolink:NamedThing Graph HGNC:3179 biolink:NamedThing Graph HGNC:318 biolink:NamedThing Graph HGNC:3180 biolink:NamedThing Graph HGNC:3182 biolink:NamedThing Graph HGNC:319 biolink:NamedThing Graph HGNC:3192 biolink:NamedThing Graph HGNC:31923 biolink:NamedThing Graph HGNC:31928 biolink:NamedThing Graph HGNC:31948 biolink:NamedThing Graph HGNC:321 biolink:NamedThing Graph HGNC:3214 biolink:NamedThing Graph HGNC:3218 biolink:NamedThing Graph HGNC:3219 biolink:NamedThing Graph HGNC:3226 biolink:NamedThing Graph HGNC:3229 biolink:NamedThing Graph HGNC:3233 biolink:NamedThing Graph HGNC:3236 biolink:NamedThing Graph HGNC:3239 biolink:NamedThing Graph HGNC:32434 biolink:NamedThing Graph HGNC:32456 biolink:NamedThing Graph HGNC:3247 biolink:NamedThing Graph HGNC:325 biolink:NamedThing Graph HGNC:32528 biolink:NamedThing Graph HGNC:3255 biolink:NamedThing Graph HGNC:32550 biolink:NamedThing Graph HGNC:3267 biolink:NamedThing Graph HGNC:32685 biolink:NamedThing Graph HGNC:32689 biolink:NamedThing Graph HGNC:32698 biolink:NamedThing Graph HGNC:327 biolink:NamedThing Graph HGNC:32700 biolink:NamedThing Graph HGNC:3287 biolink:NamedThing Graph HGNC:329 biolink:NamedThing Graph HGNC:32952 biolink:NamedThing Graph HGNC:3296 biolink:NamedThing Graph HGNC:33 biolink:NamedThing Graph HGNC:3309 biolink:NamedThing Graph HGNC:3327 biolink:NamedThing Graph HGNC:3330 biolink:NamedThing Graph HGNC:3331 biolink:NamedThing Graph HGNC:3334 biolink:NamedThing Graph HGNC:3337 biolink:NamedThing Graph HGNC:3344 biolink:NamedThing Graph HGNC:3349 biolink:NamedThing Graph HGNC:3354 biolink:NamedThing Graph HGNC:33551 biolink:NamedThing Graph HGNC:3356 biolink:NamedThing Graph HGNC:3363 biolink:NamedThing Graph HGNC:33699 biolink:NamedThing Graph HGNC:3373 biolink:NamedThing Graph HGNC:3374 biolink:NamedThing Graph HGNC:3377 biolink:NamedThing Graph HGNC:33778 biolink:NamedThing Graph HGNC:3378 biolink:NamedThing Graph HGNC:3381 biolink:NamedThing Graph HGNC:33848 biolink:NamedThing Graph HGNC:3386 biolink:NamedThing Graph HGNC:33862 biolink:NamedThing Graph HGNC:3393 biolink:NamedThing Graph HGNC:3395 biolink:NamedThing Graph HGNC:34 biolink:NamedThing Graph HGNC:34016 biolink:NamedThing Graph HGNC:341 biolink:NamedThing Graph HGNC:3415 biolink:NamedThing Graph HGNC:3416 biolink:NamedThing Graph HGNC:3420 biolink:NamedThing Graph HGNC:343 biolink:NamedThing Graph HGNC:3431 biolink:NamedThing Graph HGNC:3432 biolink:NamedThing Graph HGNC:3433 biolink:NamedThing Graph HGNC:3434 biolink:NamedThing Graph HGNC:3435 biolink:NamedThing Graph HGNC:3436 biolink:NamedThing Graph HGNC:3437 biolink:NamedThing Graph HGNC:3438 biolink:NamedThing Graph HGNC:34383 biolink:NamedThing Graph HGNC:3439 biolink:NamedThing Graph HGNC:34399 biolink:NamedThing Graph HGNC:3444 biolink:NamedThing Graph HGNC:3467 biolink:NamedThing Graph HGNC:3473 biolink:NamedThing Graph HGNC:3481 biolink:NamedThing Graph HGNC:3482 biolink:NamedThing Graph HGNC:3483 biolink:NamedThing Graph HGNC:3495 biolink:NamedThing Graph HGNC:3498 biolink:NamedThing Graph HGNC:3508 biolink:NamedThing Graph HGNC:3512 biolink:NamedThing Graph HGNC:35126 biolink:NamedThing Graph HGNC:3513 biolink:NamedThing Graph HGNC:3518 biolink:NamedThing Graph HGNC:3519 biolink:NamedThing Graph HGNC:3522 biolink:NamedThing Graph HGNC:3527 biolink:NamedThing Graph HGNC:3528 biolink:NamedThing Graph HGNC:3529 biolink:NamedThing Graph HGNC:3530 biolink:NamedThing Graph HGNC:3531 biolink:NamedThing Graph HGNC:3534 biolink:NamedThing Graph HGNC:3535 biolink:NamedThing Graph HGNC:3542 biolink:NamedThing Graph HGNC:3544 biolink:NamedThing Graph HGNC:3546 biolink:NamedThing Graph HGNC:3551 biolink:NamedThing Graph HGNC:3553 biolink:NamedThing Graph HGNC:3571 biolink:NamedThing Graph HGNC:3573 biolink:NamedThing Graph HGNC:3579 biolink:NamedThing Graph HGNC:358 biolink:NamedThing Graph HGNC:3581 biolink:NamedThing Graph HGNC:3582 biolink:NamedThing Graph HGNC:3583 biolink:NamedThing Graph HGNC:3584 biolink:NamedThing Graph HGNC:3585 biolink:NamedThing Graph HGNC:3586 biolink:NamedThing Graph HGNC:3587 biolink:NamedThing Graph HGNC:3588 biolink:NamedThing Graph HGNC:359 biolink:NamedThing Graph HGNC:360 biolink:NamedThing Graph HGNC:3600 biolink:NamedThing Graph HGNC:3602 biolink:NamedThing Graph HGNC:3603 biolink:NamedThing Graph HGNC:3604 biolink:NamedThing Graph HGNC:3606 biolink:NamedThing Graph HGNC:361 biolink:NamedThing Graph HGNC:3619 biolink:NamedThing Graph HGNC:362 biolink:NamedThing Graph HGNC:3622 biolink:NamedThing Graph HGNC:3625 biolink:NamedThing Graph HGNC:3631 biolink:NamedThing Graph HGNC:3642 biolink:NamedThing Graph HGNC:3647 biolink:NamedThing Graph HGNC:3663 biolink:NamedThing Graph HGNC:3666 biolink:NamedThing Graph HGNC:3668 biolink:NamedThing Graph HGNC:3671 biolink:NamedThing Graph HGNC:3672 biolink:NamedThing Graph HGNC:3673 biolink:NamedThing Graph HGNC:3677 biolink:NamedThing Graph HGNC:3680 biolink:NamedThing Graph HGNC:3681 biolink:NamedThing Graph HGNC:3683 biolink:NamedThing Graph HGNC:3686 biolink:NamedThing Graph HGNC:3687 biolink:NamedThing Graph HGNC:3688 biolink:NamedThing Graph HGNC:3689 biolink:NamedThing Graph HGNC:3690 biolink:NamedThing Graph HGNC:37 biolink:NamedThing Graph HGNC:3700 biolink:NamedThing Graph HGNC:3702 biolink:NamedThing Graph HGNC:3705 biolink:NamedThing Graph HGNC:3706 biolink:NamedThing Graph HGNC:37212 biolink:NamedThing Graph HGNC:37227 biolink:NamedThing Graph HGNC:37234 biolink:NamedThing Graph HGNC:37276 biolink:NamedThing Graph HGNC:3748 biolink:NamedThing Graph HGNC:3754 biolink:NamedThing Graph HGNC:3755 biolink:NamedThing Graph HGNC:3756 biolink:NamedThing Graph HGNC:3762 biolink:NamedThing Graph HGNC:3765 biolink:NamedThing Graph HGNC:3767 biolink:NamedThing Graph HGNC:3771 biolink:NamedThing Graph HGNC:3776 biolink:NamedThing Graph HGNC:3778 biolink:NamedThing Graph HGNC:379 biolink:NamedThing Graph HGNC:3791 biolink:NamedThing Graph HGNC:3800 biolink:NamedThing Graph HGNC:3801 biolink:NamedThing Graph HGNC:3804 biolink:NamedThing Graph HGNC:3806 biolink:NamedThing Graph HGNC:3808 biolink:NamedThing Graph HGNC:3809 biolink:NamedThing Graph HGNC:3811 biolink:NamedThing Graph HGNC:3823 biolink:NamedThing Graph HGNC:3861 biolink:NamedThing Graph HGNC:388 biolink:NamedThing Graph HGNC:39080 biolink:NamedThing Graph HGNC:391 biolink:NamedThing Graph HGNC:392 biolink:NamedThing Graph HGNC:393 biolink:NamedThing Graph HGNC:3942 biolink:NamedThing Graph HGNC:39433 biolink:NamedThing Graph HGNC:3945 biolink:NamedThing Graph HGNC:3948 biolink:NamedThing Graph HGNC:395 biolink:NamedThing Graph HGNC:3951 biolink:NamedThing Graph HGNC:3954 biolink:NamedThing Graph HGNC:3959 biolink:NamedThing Graph HGNC:3960 biolink:NamedThing Graph HGNC:3964 biolink:NamedThing Graph HGNC:3969 biolink:NamedThing Graph HGNC:397 biolink:NamedThing Graph HGNC:3974 biolink:NamedThing Graph HGNC:3976 biolink:NamedThing Graph HGNC:399 biolink:NamedThing Graph HGNC:3999 biolink:NamedThing Graph HGNC:40 biolink:NamedThing Graph HGNC:4006 biolink:NamedThing Graph HGNC:4010 biolink:NamedThing Graph HGNC:4017 biolink:NamedThing Graph HGNC:4026 biolink:NamedThing Graph HGNC:403 biolink:NamedThing Graph HGNC:4036 biolink:NamedThing Graph HGNC:404 biolink:NamedThing Graph HGNC:4044 biolink:NamedThing Graph HGNC:4053 biolink:NamedThing Graph HGNC:4056 biolink:NamedThing Graph HGNC:4057 biolink:NamedThing Graph HGNC:406 biolink:NamedThing Graph HGNC:4061 biolink:NamedThing Graph HGNC:4065 biolink:NamedThing Graph HGNC:4075 biolink:NamedThing Graph HGNC:408 biolink:NamedThing Graph HGNC:4081 biolink:NamedThing Graph HGNC:4083 biolink:NamedThing Graph HGNC:4084 biolink:NamedThing Graph HGNC:4087 biolink:NamedThing Graph HGNC:409 biolink:NamedThing Graph HGNC:4114 biolink:NamedThing Graph HGNC:4115 biolink:NamedThing Graph HGNC:4116 biolink:NamedThing Graph HGNC:4118 biolink:NamedThing Graph HGNC:4122 biolink:NamedThing Graph HGNC:4135 biolink:NamedThing Graph HGNC:4136 biolink:NamedThing Graph HGNC:4137 biolink:NamedThing Graph HGNC:4138 biolink:NamedThing Graph HGNC:414 biolink:NamedThing Graph HGNC:4162 biolink:NamedThing Graph HGNC:4166 biolink:NamedThing Graph HGNC:417 biolink:NamedThing Graph HGNC:4170 biolink:NamedThing Graph HGNC:4171 biolink:NamedThing Graph HGNC:4172 biolink:NamedThing Graph HGNC:4173 biolink:NamedThing Graph HGNC:4174 biolink:NamedThing Graph HGNC:4175 biolink:NamedThing Graph HGNC:4177 biolink:NamedThing Graph HGNC:4180 biolink:NamedThing Graph HGNC:4189 biolink:NamedThing Graph HGNC:4193 biolink:NamedThing Graph HGNC:4195 biolink:NamedThing Graph HGNC:4198 biolink:NamedThing Graph HGNC:42 biolink:NamedThing Graph HGNC:4204 biolink:NamedThing Graph HGNC:4206 biolink:NamedThing Graph HGNC:4214 biolink:NamedThing Graph HGNC:4217 biolink:NamedThing Graph HGNC:4218 biolink:NamedThing Graph HGNC:4220 biolink:NamedThing Graph HGNC:4221 biolink:NamedThing Graph HGNC:4223 biolink:NamedThing Graph HGNC:4226 biolink:NamedThing Graph HGNC:4232 biolink:NamedThing Graph HGNC:4235 biolink:NamedThing Graph HGNC:4236 biolink:NamedThing Graph HGNC:4237 biolink:NamedThing Graph HGNC:4238 biolink:NamedThing Graph HGNC:4241 biolink:NamedThing Graph HGNC:4247 biolink:NamedThing Graph HGNC:4250 biolink:NamedThing Graph HGNC:4261 biolink:NamedThing Graph HGNC:4263 biolink:NamedThing Graph HGNC:4268 biolink:NamedThing Graph HGNC:427 biolink:NamedThing Graph HGNC:4274 biolink:NamedThing Graph HGNC:4277 biolink:NamedThing Graph HGNC:4279 biolink:NamedThing Graph HGNC:428 biolink:NamedThing Graph HGNC:4281 biolink:NamedThing Graph HGNC:4283 biolink:NamedThing Graph HGNC:4284 biolink:NamedThing Graph HGNC:4285 biolink:NamedThing Graph HGNC:4288 biolink:NamedThing Graph HGNC:4289 biolink:NamedThing Graph HGNC:4296 biolink:NamedThing Graph HGNC:4298 biolink:NamedThing Graph HGNC:4311 biolink:NamedThing Graph HGNC:4315 biolink:NamedThing Graph HGNC:4318 biolink:NamedThing Graph HGNC:4319 biolink:NamedThing Graph HGNC:4329 biolink:NamedThing Graph HGNC:4331 biolink:NamedThing Graph HGNC:4335 biolink:NamedThing Graph HGNC:4341 biolink:NamedThing Graph HGNC:4367 biolink:NamedThing Graph HGNC:4385 biolink:NamedThing Graph HGNC:4387 biolink:NamedThing Graph HGNC:4388 biolink:NamedThing Graph HGNC:4389 biolink:NamedThing Graph HGNC:4390 biolink:NamedThing Graph HGNC:4392 biolink:NamedThing Graph HGNC:4393 biolink:NamedThing Graph HGNC:4394 biolink:NamedThing Graph HGNC:4396 biolink:NamedThing Graph HGNC:4400 biolink:NamedThing Graph HGNC:4401 biolink:NamedThing Graph HGNC:4415 biolink:NamedThing Graph HGNC:4416 biolink:NamedThing Graph HGNC:4422 biolink:NamedThing Graph HGNC:443 biolink:NamedThing Graph HGNC:4431 biolink:NamedThing Graph HGNC:4439 biolink:NamedThing Graph HGNC:4446 biolink:NamedThing Graph HGNC:445 biolink:NamedThing Graph HGNC:4451 biolink:NamedThing Graph HGNC:4454 biolink:NamedThing Graph HGNC:4455 biolink:NamedThing Graph HGNC:4458 biolink:NamedThing Graph HGNC:449 biolink:NamedThing Graph HGNC:45 biolink:NamedThing Graph HGNC:450 biolink:NamedThing Graph HGNC:451 biolink:NamedThing Graph HGNC:4510 biolink:NamedThing Graph HGNC:4512 biolink:NamedThing Graph HGNC:4516 biolink:NamedThing Graph HGNC:4519 biolink:NamedThing Graph HGNC:452 biolink:NamedThing Graph HGNC:4539 biolink:NamedThing Graph HGNC:4551 biolink:NamedThing Graph HGNC:4553 biolink:NamedThing Graph HGNC:4556 biolink:NamedThing Graph HGNC:4570 biolink:NamedThing Graph HGNC:4573 biolink:NamedThing Graph HGNC:4576 biolink:NamedThing Graph HGNC:4580 biolink:NamedThing Graph HGNC:4584 biolink:NamedThing Graph HGNC:4585 biolink:NamedThing Graph HGNC:4586 biolink:NamedThing Graph HGNC:4588 biolink:NamedThing Graph HGNC:4593 biolink:NamedThing Graph HGNC:4598 biolink:NamedThing Graph HGNC:4601 biolink:NamedThing Graph HGNC:461 biolink:NamedThing Graph HGNC:4612 biolink:NamedThing Graph HGNC:4620 biolink:NamedThing Graph HGNC:4624 biolink:NamedThing Graph HGNC:4651 biolink:NamedThing Graph HGNC:467 biolink:NamedThing Graph HGNC:4678 biolink:NamedThing Graph HGNC:4679 biolink:NamedThing Graph HGNC:468 biolink:NamedThing Graph HGNC:4685 biolink:NamedThing Graph HGNC:4688 biolink:NamedThing Graph HGNC:4689 biolink:NamedThing Graph HGNC:469 biolink:NamedThing Graph HGNC:4696 biolink:NamedThing Graph HGNC:4699 biolink:NamedThing Graph HGNC:47 biolink:NamedThing Graph HGNC:4706 biolink:NamedThing Graph HGNC:4707 biolink:NamedThing Graph HGNC:4713 biolink:NamedThing Graph HGNC:4795 biolink:NamedThing Graph HGNC:4796 biolink:NamedThing Graph HGNC:4798 biolink:NamedThing Graph HGNC:4799 biolink:NamedThing Graph HGNC:48 biolink:NamedThing Graph HGNC:4800 biolink:NamedThing Graph HGNC:4801 biolink:NamedThing Graph HGNC:4805 biolink:NamedThing Graph HGNC:4806 biolink:NamedThing Graph HGNC:4807 biolink:NamedThing Graph HGNC:4814 biolink:NamedThing Graph HGNC:4816 biolink:NamedThing Graph HGNC:4817 biolink:NamedThing Graph HGNC:4827 biolink:NamedThing Graph HGNC:483 biolink:NamedThing Graph HGNC:4832 biolink:NamedThing Graph HGNC:4837 biolink:NamedThing Graph HGNC:4838 biolink:NamedThing Graph HGNC:4839 biolink:NamedThing Graph HGNC:4845 biolink:NamedThing Graph HGNC:4847 biolink:NamedThing Graph HGNC:4851 biolink:NamedThing Graph HGNC:4861 biolink:NamedThing Graph HGNC:4867 biolink:NamedThing Graph HGNC:4868 biolink:NamedThing Graph HGNC:4877 biolink:NamedThing Graph HGNC:4878 biolink:NamedThing Graph HGNC:4879 biolink:NamedThing Graph HGNC:4883 biolink:NamedThing Graph HGNC:4886 biolink:NamedThing Graph HGNC:4887 biolink:NamedThing Graph HGNC:4892 biolink:NamedThing Graph HGNC:4893 biolink:NamedThing Graph HGNC:4908 biolink:NamedThing Graph HGNC:491 biolink:NamedThing Graph HGNC:4912 biolink:NamedThing Graph HGNC:492 biolink:NamedThing Graph HGNC:4921 biolink:NamedThing Graph HGNC:4922 biolink:NamedThing Graph HGNC:493 biolink:NamedThing Graph HGNC:4932 biolink:NamedThing Graph HGNC:4933 biolink:NamedThing Graph HGNC:494 biolink:NamedThing Graph HGNC:4948 biolink:NamedThing Graph HGNC:496 biolink:NamedThing Graph HGNC:497 biolink:NamedThing Graph HGNC:4976 biolink:NamedThing Graph HGNC:4978 biolink:NamedThing Graph HGNC:4979 biolink:NamedThing Graph HGNC:4982 biolink:NamedThing Graph HGNC:5004 biolink:NamedThing Graph HGNC:5005 biolink:NamedThing Graph HGNC:5008 biolink:NamedThing Graph HGNC:5009 biolink:NamedThing Graph HGNC:5013 biolink:NamedThing Graph HGNC:5017 biolink:NamedThing Graph HGNC:5024 biolink:NamedThing Graph HGNC:5028 biolink:NamedThing Graph HGNC:5031 biolink:NamedThing Graph HGNC:5033 biolink:NamedThing Graph HGNC:5037 biolink:NamedThing Graph HGNC:5042 biolink:NamedThing Graph HGNC:5044 biolink:NamedThing Graph HGNC:5099 biolink:NamedThing Graph HGNC:5101 biolink:NamedThing Graph HGNC:5102 biolink:NamedThing Graph HGNC:5103 biolink:NamedThing Graph HGNC:5111 biolink:NamedThing Graph HGNC:5125 biolink:NamedThing Graph HGNC:5133 biolink:NamedThing Graph HGNC:5136 biolink:NamedThing Graph HGNC:5141 biolink:NamedThing Graph HGNC:5144 biolink:NamedThing Graph HGNC:5147 biolink:NamedThing Graph HGNC:5154 biolink:NamedThing Graph HGNC:5157 biolink:NamedThing Graph HGNC:5163 biolink:NamedThing Graph HGNC:5172 biolink:NamedThing Graph HGNC:5173 biolink:NamedThing Graph HGNC:5181 biolink:NamedThing Graph HGNC:5201 biolink:NamedThing Graph HGNC:5208 biolink:NamedThing Graph HGNC:5209 biolink:NamedThing Graph HGNC:5212 biolink:NamedThing Graph HGNC:5213 biolink:NamedThing Graph HGNC:5218 biolink:NamedThing Graph HGNC:5227 biolink:NamedThing Graph HGNC:5228 biolink:NamedThing Graph HGNC:5244 biolink:NamedThing Graph HGNC:5246 biolink:NamedThing Graph HGNC:5248 biolink:NamedThing Graph HGNC:5261 biolink:NamedThing Graph HGNC:5273 biolink:NamedThing Graph HGNC:5285 biolink:NamedThing Graph HGNC:5286 biolink:NamedThing Graph HGNC:5293 biolink:NamedThing Graph HGNC:53 biolink:NamedThing Graph HGNC:5318 biolink:NamedThing Graph HGNC:5320 biolink:NamedThing Graph HGNC:5321 biolink:NamedThing Graph HGNC:5330 biolink:NamedThing Graph HGNC:5331 biolink:NamedThing Graph HGNC:5351 biolink:NamedThing Graph HGNC:5358 biolink:NamedThing Graph HGNC:5383 biolink:NamedThing Graph HGNC:5385 biolink:NamedThing Graph HGNC:5389 biolink:NamedThing Graph HGNC:5391 biolink:NamedThing Graph HGNC:5394 biolink:NamedThing Graph HGNC:5401 biolink:NamedThing Graph HGNC:5414 biolink:NamedThing Graph HGNC:543 biolink:NamedThing Graph HGNC:5433 biolink:NamedThing Graph HGNC:5439 biolink:NamedThing Graph HGNC:5440 biolink:NamedThing Graph HGNC:5461 biolink:NamedThing Graph HGNC:5464 biolink:NamedThing Graph HGNC:5465 biolink:NamedThing Graph HGNC:5466 biolink:NamedThing Graph HGNC:5468 biolink:NamedThing Graph HGNC:5476 biolink:NamedThing Graph HGNC:5541 biolink:NamedThing Graph HGNC:5542 biolink:NamedThing Graph HGNC:559 biolink:NamedThing Graph HGNC:565 biolink:NamedThing Graph HGNC:566 biolink:NamedThing Graph HGNC:567 biolink:NamedThing Graph HGNC:568 biolink:NamedThing Graph HGNC:57 biolink:NamedThing Graph HGNC:5716 biolink:NamedThing Graph HGNC:572 biolink:NamedThing Graph HGNC:5724 biolink:NamedThing Graph HGNC:573 biolink:NamedThing Graph HGNC:574 biolink:NamedThing Graph HGNC:575 biolink:NamedThing Graph HGNC:583 biolink:NamedThing Graph HGNC:5870 biolink:NamedThing Graph HGNC:59 biolink:NamedThing Graph HGNC:592 biolink:NamedThing Graph HGNC:5948 biolink:NamedThing Graph HGNC:5950 biolink:NamedThing Graph HGNC:5956 biolink:NamedThing Graph HGNC:5959 biolink:NamedThing Graph HGNC:5960 biolink:NamedThing Graph HGNC:5961 biolink:NamedThing Graph HGNC:5964 biolink:NamedThing Graph HGNC:5965 biolink:NamedThing Graph HGNC:5967 biolink:NamedThing Graph HGNC:5970 biolink:NamedThing Graph HGNC:5971 biolink:NamedThing Graph HGNC:5973 biolink:NamedThing Graph HGNC:5985 biolink:NamedThing Graph HGNC:5996 biolink:NamedThing Graph HGNC:60 biolink:NamedThing Graph HGNC:600 biolink:NamedThing Graph HGNC:6000 biolink:NamedThing Graph HGNC:6005 biolink:NamedThing Graph HGNC:6006 biolink:NamedThing Graph HGNC:6008 biolink:NamedThing Graph HGNC:6010 biolink:NamedThing Graph HGNC:6018 biolink:NamedThing Graph HGNC:6024 biolink:NamedThing Graph HGNC:6027 biolink:NamedThing Graph HGNC:603 biolink:NamedThing Graph HGNC:6050 biolink:NamedThing Graph HGNC:6052 biolink:NamedThing Graph HGNC:6055 biolink:NamedThing Graph HGNC:6080 biolink:NamedThing Graph HGNC:6081 biolink:NamedThing Graph HGNC:609 biolink:NamedThing Graph HGNC:6091 biolink:NamedThing Graph HGNC:61 biolink:NamedThing Graph HGNC:610 biolink:NamedThing Graph HGNC:6106 biolink:NamedThing Graph HGNC:6107 biolink:NamedThing Graph HGNC:6118 biolink:NamedThing Graph HGNC:6120 biolink:NamedThing Graph HGNC:6121 biolink:NamedThing Graph HGNC:6122 biolink:NamedThing Graph HGNC:613 biolink:NamedThing Graph HGNC:6137 biolink:NamedThing Graph HGNC:6139 biolink:NamedThing Graph HGNC:6143 biolink:NamedThing Graph HGNC:6149 biolink:NamedThing Graph HGNC:6155 biolink:NamedThing Graph HGNC:6161 biolink:NamedThing Graph HGNC:6171 biolink:NamedThing Graph HGNC:6172 biolink:NamedThing Graph HGNC:6174 biolink:NamedThing Graph HGNC:6176 biolink:NamedThing Graph HGNC:618 biolink:NamedThing Graph HGNC:6181 biolink:NamedThing Graph HGNC:6186 biolink:NamedThing Graph HGNC:6188 biolink:NamedThing Graph HGNC:6190 biolink:NamedThing Graph HGNC:6192 biolink:NamedThing Graph HGNC:6193 biolink:NamedThing Graph HGNC:620 biolink:NamedThing Graph HGNC:6207 biolink:NamedThing Graph HGNC:6211 biolink:NamedThing Graph HGNC:6215 biolink:NamedThing Graph HGNC:6217 biolink:NamedThing Graph HGNC:6218 biolink:NamedThing Graph HGNC:6220 biolink:NamedThing Graph HGNC:6224 biolink:NamedThing Graph HGNC:6231 biolink:NamedThing Graph HGNC:6233 biolink:NamedThing Graph HGNC:6235 biolink:NamedThing Graph HGNC:6239 biolink:NamedThing Graph HGNC:6240 biolink:NamedThing Graph HGNC:6242 biolink:NamedThing Graph HGNC:6243 biolink:NamedThing Graph HGNC:6250 biolink:NamedThing Graph HGNC:6251 biolink:NamedThing Graph HGNC:6255 biolink:NamedThing Graph HGNC:6256 biolink:NamedThing Graph HGNC:6257 biolink:NamedThing Graph HGNC:6259 biolink:NamedThing Graph HGNC:626 biolink:NamedThing Graph HGNC:6263 biolink:NamedThing Graph HGNC:6266 biolink:NamedThing Graph HGNC:6267 biolink:NamedThing Graph HGNC:6278 biolink:NamedThing Graph HGNC:6283 biolink:NamedThing Graph HGNC:6284 biolink:NamedThing Graph HGNC:6293 biolink:NamedThing Graph HGNC:6294 biolink:NamedThing Graph HGNC:6296 biolink:NamedThing Graph HGNC:6297 biolink:NamedThing Graph HGNC:6298 biolink:NamedThing Graph HGNC:6309 biolink:NamedThing Graph HGNC:6315 biolink:NamedThing Graph HGNC:6317 biolink:NamedThing Graph HGNC:6318 biolink:NamedThing Graph HGNC:6323 biolink:NamedThing Graph HGNC:6325 biolink:NamedThing Graph HGNC:634 biolink:NamedThing Graph HGNC:6341 biolink:NamedThing Graph HGNC:6342 biolink:NamedThing Graph HGNC:6343 biolink:NamedThing Graph HGNC:6345 biolink:NamedThing Graph HGNC:6354 biolink:NamedThing Graph HGNC:6357 biolink:NamedThing Graph HGNC:6365 biolink:NamedThing Graph HGNC:6371 biolink:NamedThing Graph HGNC:638 biolink:NamedThing Graph HGNC:6383 biolink:NamedThing Graph HGNC:6388 biolink:NamedThing Graph HGNC:6391 biolink:NamedThing Graph HGNC:6404 biolink:NamedThing Graph HGNC:6407 biolink:NamedThing Graph HGNC:6408 biolink:NamedThing Graph HGNC:6412 biolink:NamedThing Graph HGNC:6413 biolink:NamedThing Graph HGNC:6415 biolink:NamedThing Graph HGNC:6416 biolink:NamedThing Graph HGNC:6423 biolink:NamedThing Graph HGNC:6427 biolink:NamedThing Graph HGNC:6439 biolink:NamedThing Graph HGNC:644 biolink:NamedThing Graph HGNC:6441 biolink:NamedThing Graph HGNC:6442 biolink:NamedThing Graph HGNC:6443 biolink:NamedThing Graph HGNC:6444 biolink:NamedThing Graph HGNC:6462 biolink:NamedThing Graph HGNC:6469 biolink:NamedThing Graph HGNC:6470 biolink:NamedThing Graph HGNC:6481 biolink:NamedThing Graph HGNC:6482 biolink:NamedThing Graph HGNC:6483 biolink:NamedThing Graph HGNC:6484 biolink:NamedThing Graph HGNC:6485 biolink:NamedThing Graph HGNC:6486 biolink:NamedThing Graph HGNC:6487 biolink:NamedThing Graph HGNC:649 biolink:NamedThing Graph HGNC:6490 biolink:NamedThing Graph HGNC:6494 biolink:NamedThing Graph HGNC:6501 biolink:NamedThing Graph HGNC:6502 biolink:NamedThing Graph HGNC:6511 biolink:NamedThing Graph HGNC:6512 biolink:NamedThing Graph HGNC:6518 biolink:NamedThing Graph HGNC:6522 biolink:NamedThing Graph HGNC:6524 biolink:NamedThing Graph HGNC:6530 biolink:NamedThing Graph HGNC:6535 biolink:NamedThing Graph HGNC:6541 biolink:NamedThing Graph HGNC:6545 biolink:NamedThing Graph HGNC:6553 biolink:NamedThing Graph HGNC:6554 biolink:NamedThing Graph HGNC:6560 biolink:NamedThing Graph HGNC:6572 biolink:NamedThing Graph HGNC:6584 biolink:NamedThing Graph HGNC:6585 biolink:NamedThing Graph HGNC:6595 biolink:NamedThing Graph HGNC:6597 biolink:NamedThing Graph HGNC:6601 biolink:NamedThing Graph HGNC:6610 biolink:NamedThing Graph HGNC:6617 biolink:NamedThing Graph HGNC:6619 biolink:NamedThing Graph HGNC:6621 biolink:NamedThing Graph HGNC:663 biolink:NamedThing Graph HGNC:6631 biolink:NamedThing Graph HGNC:6636 biolink:NamedThing Graph HGNC:6637 biolink:NamedThing Graph HGNC:6638 biolink:NamedThing Graph HGNC:6649 biolink:NamedThing Graph HGNC:6654 biolink:NamedThing Graph HGNC:6663 biolink:NamedThing Graph HGNC:6664 biolink:NamedThing Graph HGNC:6665 biolink:NamedThing Graph HGNC:6677 biolink:NamedThing Graph HGNC:6685 biolink:NamedThing Graph HGNC:6692 biolink:NamedThing Graph HGNC:6694 biolink:NamedThing Graph HGNC:6696 biolink:NamedThing Graph HGNC:6697 biolink:NamedThing Graph HGNC:6698 biolink:NamedThing Graph HGNC:67 biolink:NamedThing Graph HGNC:6701 biolink:NamedThing Graph HGNC:6708 biolink:NamedThing Graph HGNC:6709 biolink:NamedThing Graph HGNC:6715 biolink:NamedThing Graph HGNC:6716 biolink:NamedThing Graph HGNC:6717 biolink:NamedThing Graph HGNC:6719 biolink:NamedThing Graph HGNC:6741 biolink:NamedThing Graph HGNC:6742 biolink:NamedThing Graph HGNC:6758 biolink:NamedThing Graph HGNC:6764 biolink:NamedThing Graph HGNC:6769 biolink:NamedThing Graph HGNC:6770 biolink:NamedThing Graph HGNC:6772 biolink:NamedThing Graph HGNC:6773 biolink:NamedThing Graph HGNC:6774 biolink:NamedThing Graph HGNC:6776 biolink:NamedThing Graph HGNC:678 biolink:NamedThing Graph HGNC:6783 biolink:NamedThing Graph HGNC:68 biolink:NamedThing Graph HGNC:6814 biolink:NamedThing Graph HGNC:6816 biolink:NamedThing Graph HGNC:6819 biolink:NamedThing Graph HGNC:6823 biolink:NamedThing Graph HGNC:6826 biolink:NamedThing Graph HGNC:6831 biolink:NamedThing Graph HGNC:6833 biolink:NamedThing Graph HGNC:6840 biolink:NamedThing Graph HGNC:6842 biolink:NamedThing Graph HGNC:6848 biolink:NamedThing Graph HGNC:685 biolink:NamedThing Graph HGNC:6853 biolink:NamedThing Graph HGNC:6859 biolink:NamedThing Graph HGNC:6888 biolink:NamedThing Graph HGNC:6891 biolink:NamedThing Graph HGNC:6893 biolink:NamedThing Graph HGNC:6898 biolink:NamedThing Graph HGNC:6901 biolink:NamedThing Graph HGNC:6902 biolink:NamedThing Graph HGNC:6903 biolink:NamedThing Graph HGNC:6909 biolink:NamedThing Graph HGNC:691 biolink:NamedThing Graph HGNC:6912 biolink:NamedThing Graph HGNC:6922 biolink:NamedThing Graph HGNC:6929 biolink:NamedThing Graph HGNC:6930 biolink:NamedThing Graph HGNC:6932 biolink:NamedThing Graph HGNC:6936 biolink:NamedThing Graph HGNC:6937 biolink:NamedThing Graph HGNC:6938 biolink:NamedThing Graph HGNC:6944 biolink:NamedThing Graph HGNC:6947 biolink:NamedThing Graph HGNC:6949 biolink:NamedThing Graph HGNC:6953 biolink:NamedThing Graph HGNC:6954 biolink:NamedThing Graph HGNC:697 biolink:NamedThing Graph HGNC:6971 biolink:NamedThing Graph HGNC:6990 biolink:NamedThing Graph HGNC:6993 biolink:NamedThing Graph HGNC:6996 biolink:NamedThing Graph HGNC:6998 biolink:NamedThing Graph HGNC:7001 biolink:NamedThing Graph HGNC:7010 biolink:NamedThing Graph HGNC:7013 biolink:NamedThing Graph HGNC:7027 biolink:NamedThing Graph HGNC:7029 biolink:NamedThing Graph HGNC:7045 biolink:NamedThing Graph HGNC:7060 biolink:NamedThing Graph HGNC:7095 biolink:NamedThing Graph HGNC:7096 biolink:NamedThing Graph HGNC:7103 biolink:NamedThing Graph HGNC:7104 biolink:NamedThing Graph HGNC:7105 biolink:NamedThing Graph HGNC:7106 biolink:NamedThing Graph HGNC:7108 biolink:NamedThing Graph HGNC:7114 biolink:NamedThing Graph HGNC:7121 biolink:NamedThing Graph HGNC:7127 biolink:NamedThing Graph HGNC:7128 biolink:NamedThing Graph HGNC:713 biolink:NamedThing Graph HGNC:7132 biolink:NamedThing Graph HGNC:7133 biolink:NamedThing Graph HGNC:714 biolink:NamedThing Graph HGNC:7146 biolink:NamedThing Graph HGNC:7150 biolink:NamedThing Graph HGNC:7154 biolink:NamedThing Graph HGNC:7159 biolink:NamedThing Graph HGNC:7160 biolink:NamedThing Graph HGNC:7165 biolink:NamedThing Graph HGNC:7166 biolink:NamedThing Graph HGNC:7167 biolink:NamedThing Graph HGNC:7173 biolink:NamedThing Graph HGNC:7176 biolink:NamedThing Graph HGNC:7179 biolink:NamedThing Graph HGNC:719 biolink:NamedThing Graph HGNC:7190 biolink:NamedThing Graph HGNC:7193 biolink:NamedThing Graph HGNC:7197 biolink:NamedThing Graph HGNC:7207 biolink:NamedThing Graph HGNC:7208 biolink:NamedThing Graph HGNC:7216 biolink:NamedThing Graph HGNC:7217 biolink:NamedThing Graph HGNC:7218 biolink:NamedThing Graph HGNC:7224 biolink:NamedThing Graph HGNC:7225 biolink:NamedThing Graph HGNC:7230 biolink:NamedThing Graph HGNC:7315 biolink:NamedThing Graph HGNC:7323 biolink:NamedThing Graph HGNC:7325 biolink:NamedThing Graph HGNC:7329 biolink:NamedThing Graph HGNC:735 biolink:NamedThing Graph HGNC:7372 biolink:NamedThing Graph HGNC:7373 biolink:NamedThing Graph HGNC:7381 biolink:NamedThing Graph HGNC:7391 biolink:NamedThing Graph HGNC:7392 biolink:NamedThing Graph HGNC:7414 biolink:NamedThing Graph HGNC:7436 biolink:NamedThing Graph HGNC:7448 biolink:NamedThing Graph HGNC:7450 biolink:NamedThing Graph HGNC:7455 biolink:NamedThing Graph HGNC:7458 biolink:NamedThing Graph HGNC:746 biolink:NamedThing Graph HGNC:7461 biolink:NamedThing Graph HGNC:7462 biolink:NamedThing Graph HGNC:7467 biolink:NamedThing Graph HGNC:7468 biolink:NamedThing Graph HGNC:7473 biolink:NamedThing Graph HGNC:7477 biolink:NamedThing Graph HGNC:7487 biolink:NamedThing Graph HGNC:7489 biolink:NamedThing Graph HGNC:7490 biolink:NamedThing Graph HGNC:7495 biolink:NamedThing Graph HGNC:7497 biolink:NamedThing Graph HGNC:7498 biolink:NamedThing Graph HGNC:7499 biolink:NamedThing Graph HGNC:7508 biolink:NamedThing Graph HGNC:7523 biolink:NamedThing Graph HGNC:7525 biolink:NamedThing Graph HGNC:7526 biolink:NamedThing Graph HGNC:7527 biolink:NamedThing Graph HGNC:7529 biolink:NamedThing Graph HGNC:753 biolink:NamedThing Graph HGNC:7530 biolink:NamedThing Graph HGNC:7549 biolink:NamedThing Graph HGNC:7551 biolink:NamedThing Graph HGNC:7553 biolink:NamedThing Graph HGNC:7559 biolink:NamedThing Graph HGNC:756 biolink:NamedThing Graph HGNC:7562 biolink:NamedThing Graph HGNC:7569 biolink:NamedThing Graph HGNC:757 biolink:NamedThing Graph HGNC:7572 biolink:NamedThing Graph HGNC:7573 biolink:NamedThing Graph HGNC:7576 biolink:NamedThing Graph HGNC:7577 biolink:NamedThing Graph HGNC:7578 biolink:NamedThing Graph HGNC:7579 biolink:NamedThing Graph HGNC:758 biolink:NamedThing Graph HGNC:7582 biolink:NamedThing Graph HGNC:7583 biolink:NamedThing Graph HGNC:7584 biolink:NamedThing Graph HGNC:7585 biolink:NamedThing Graph HGNC:7590 biolink:NamedThing Graph HGNC:7594 biolink:NamedThing Graph HGNC:7595 biolink:NamedThing Graph HGNC:7599 biolink:NamedThing Graph HGNC:7601 biolink:NamedThing Graph HGNC:7602 biolink:NamedThing Graph HGNC:7603 biolink:NamedThing Graph HGNC:7605 biolink:NamedThing Graph HGNC:7606 biolink:NamedThing Graph HGNC:7609 biolink:NamedThing Graph HGNC:7610 biolink:NamedThing Graph HGNC:7623 biolink:NamedThing Graph HGNC:7631 biolink:NamedThing Graph HGNC:7632 biolink:NamedThing Graph HGNC:7643 biolink:NamedThing Graph HGNC:7646 biolink:NamedThing Graph HGNC:7652 biolink:NamedThing Graph HGNC:7660 biolink:NamedThing Graph HGNC:7661 biolink:NamedThing Graph HGNC:7662 biolink:NamedThing Graph HGNC:7677 biolink:NamedThing Graph HGNC:7678 biolink:NamedThing Graph HGNC:7679 biolink:NamedThing Graph HGNC:7680 biolink:NamedThing Graph HGNC:7683 biolink:NamedThing Graph HGNC:7684 biolink:NamedThing Graph HGNC:7685 biolink:NamedThing Graph HGNC:7690 biolink:NamedThing Graph HGNC:7693 biolink:NamedThing Graph HGNC:7698 biolink:NamedThing Graph HGNC:7703 biolink:NamedThing Graph HGNC:7704 biolink:NamedThing Graph HGNC:7707 biolink:NamedThing Graph HGNC:7708 biolink:NamedThing Graph HGNC:7710 biolink:NamedThing Graph HGNC:7711 biolink:NamedThing Graph HGNC:7713 biolink:NamedThing Graph HGNC:7714 biolink:NamedThing Graph HGNC:7715 biolink:NamedThing Graph HGNC:7716 biolink:NamedThing Graph HGNC:7717 biolink:NamedThing Graph HGNC:7720 biolink:NamedThing Graph HGNC:7728 biolink:NamedThing Graph HGNC:7737 biolink:NamedThing Graph HGNC:7739 biolink:NamedThing Graph HGNC:7744 biolink:NamedThing Graph HGNC:7745 biolink:NamedThing Graph HGNC:775 biolink:NamedThing Graph HGNC:7758 biolink:NamedThing Graph HGNC:7762 biolink:NamedThing Graph HGNC:7765 biolink:NamedThing Graph HGNC:7773 biolink:NamedThing Graph HGNC:7784 biolink:NamedThing Graph HGNC:7788 biolink:NamedThing Graph HGNC:779 biolink:NamedThing Graph HGNC:7794 biolink:NamedThing Graph HGNC:7795 biolink:NamedThing Graph HGNC:7797 biolink:NamedThing Graph HGNC:7808 biolink:NamedThing Graph HGNC:7820 biolink:NamedThing Graph HGNC:7863 biolink:NamedThing Graph HGNC:7865 biolink:NamedThing Graph HGNC:7866 biolink:NamedThing Graph HGNC:7869 biolink:NamedThing Graph HGNC:7871 biolink:NamedThing Graph HGNC:7881 biolink:NamedThing Graph HGNC:7882 biolink:NamedThing Graph HGNC:7883 biolink:NamedThing Graph HGNC:7892 biolink:NamedThing Graph HGNC:7897 biolink:NamedThing Graph HGNC:7905 biolink:NamedThing Graph HGNC:7907 biolink:NamedThing Graph HGNC:7908 biolink:NamedThing Graph HGNC:791 biolink:NamedThing Graph HGNC:7939 biolink:NamedThing Graph HGNC:794 biolink:NamedThing Graph HGNC:7944 biolink:NamedThing Graph HGNC:795 biolink:NamedThing Graph HGNC:7960 biolink:NamedThing Graph HGNC:7967 biolink:NamedThing Graph HGNC:7974 biolink:NamedThing Graph HGNC:7975 biolink:NamedThing Graph HGNC:7976 biolink:NamedThing Graph HGNC:7978 biolink:NamedThing Graph HGNC:7979 biolink:NamedThing Graph HGNC:7983 biolink:NamedThing Graph HGNC:7989 biolink:NamedThing Graph HGNC:799 biolink:NamedThing Graph HGNC:7997 biolink:NamedThing Graph HGNC:800 biolink:NamedThing Graph HGNC:8002 biolink:NamedThing Graph HGNC:8008 biolink:NamedThing Graph HGNC:801 biolink:NamedThing Graph HGNC:8011 biolink:NamedThing Graph HGNC:8021 biolink:NamedThing Graph HGNC:8022 biolink:NamedThing Graph HGNC:8024 biolink:NamedThing Graph HGNC:8028 biolink:NamedThing Graph HGNC:8031 biolink:NamedThing Graph HGNC:8032 biolink:NamedThing Graph HGNC:8063 biolink:NamedThing Graph HGNC:8066 biolink:NamedThing Graph HGNC:8067 biolink:NamedThing Graph HGNC:8079 biolink:NamedThing Graph HGNC:8082 biolink:NamedThing Graph HGNC:8086 biolink:NamedThing Graph HGNC:8091 biolink:NamedThing Graph HGNC:8104 biolink:NamedThing Graph HGNC:8108 biolink:NamedThing Graph HGNC:8109 biolink:NamedThing Graph HGNC:811 biolink:NamedThing Graph HGNC:812 biolink:NamedThing Graph HGNC:8124 biolink:NamedThing Graph HGNC:8140 biolink:NamedThing Graph HGNC:8142 biolink:NamedThing Graph HGNC:8148 biolink:NamedThing Graph HGNC:8149 biolink:NamedThing Graph HGNC:815 biolink:NamedThing Graph HGNC:8157 biolink:NamedThing Graph HGNC:823 biolink:NamedThing Graph HGNC:838 biolink:NamedThing Graph HGNC:84 biolink:NamedThing Graph HGNC:8487 biolink:NamedThing Graph HGNC:8490 biolink:NamedThing Graph HGNC:8507 biolink:NamedThing Graph HGNC:8512 biolink:NamedThing Graph HGNC:8515 biolink:NamedThing Graph HGNC:8516 biolink:NamedThing Graph HGNC:8522 biolink:NamedThing Graph HGNC:8527 biolink:NamedThing Graph HGNC:853 biolink:NamedThing Graph HGNC:854 biolink:NamedThing Graph HGNC:8547 biolink:NamedThing Graph HGNC:8548 biolink:NamedThing Graph HGNC:8549 biolink:NamedThing Graph HGNC:8565 biolink:NamedThing Graph HGNC:8574 biolink:NamedThing Graph HGNC:8582 biolink:NamedThing Graph HGNC:8583 biolink:NamedThing Graph HGNC:8592 biolink:NamedThing Graph HGNC:8604 biolink:NamedThing Graph HGNC:8607 biolink:NamedThing Graph HGNC:8609 biolink:NamedThing Graph HGNC:8615 biolink:NamedThing Graph HGNC:8616 biolink:NamedThing Graph HGNC:8617 biolink:NamedThing Graph HGNC:8618 biolink:NamedThing Graph HGNC:8619 biolink:NamedThing Graph HGNC:8620 biolink:NamedThing Graph HGNC:8623 biolink:NamedThing Graph HGNC:8636 biolink:NamedThing Graph HGNC:8646 biolink:NamedThing Graph HGNC:866 biolink:NamedThing Graph HGNC:868 biolink:NamedThing Graph HGNC:869 biolink:NamedThing Graph HGNC:87 biolink:NamedThing Graph HGNC:870 biolink:NamedThing Graph HGNC:8724 biolink:NamedThing Graph HGNC:8725 biolink:NamedThing Graph HGNC:8729 biolink:NamedThing Graph HGNC:8740 biolink:NamedThing Graph HGNC:8743 biolink:NamedThing Graph HGNC:8754 biolink:NamedThing Graph HGNC:8761 biolink:NamedThing Graph HGNC:8768 biolink:NamedThing Graph HGNC:877 biolink:NamedThing Graph HGNC:8772 biolink:NamedThing Graph HGNC:8773 biolink:NamedThing Graph HGNC:8778 biolink:NamedThing Graph HGNC:8783 biolink:NamedThing Graph HGNC:8785 biolink:NamedThing Graph HGNC:8786 biolink:NamedThing Graph HGNC:8787 biolink:NamedThing Graph HGNC:8788 biolink:NamedThing Graph HGNC:8789 biolink:NamedThing Graph HGNC:8790 biolink:NamedThing Graph HGNC:8794 biolink:NamedThing Graph HGNC:8800 biolink:NamedThing Graph HGNC:8803 biolink:NamedThing Graph HGNC:8804 biolink:NamedThing Graph HGNC:8806 biolink:NamedThing Graph HGNC:8808 biolink:NamedThing Graph HGNC:8819 biolink:NamedThing Graph HGNC:882 biolink:NamedThing Graph HGNC:8820 biolink:NamedThing Graph HGNC:8824 biolink:NamedThing Graph HGNC:8840 biolink:NamedThing Graph HGNC:8846 biolink:NamedThing Graph HGNC:8847 biolink:NamedThing Graph HGNC:8850 biolink:NamedThing Graph HGNC:8851 biolink:NamedThing Graph HGNC:8853 biolink:NamedThing Graph HGNC:8854 biolink:NamedThing Graph HGNC:8855 biolink:NamedThing Graph HGNC:8856 biolink:NamedThing Graph HGNC:8857 biolink:NamedThing Graph HGNC:8858 biolink:NamedThing Graph HGNC:8859 biolink:NamedThing Graph HGNC:886 biolink:NamedThing Graph HGNC:8860 biolink:NamedThing Graph HGNC:8864 biolink:NamedThing Graph HGNC:8877 biolink:NamedThing Graph HGNC:888 biolink:NamedThing Graph HGNC:8881 biolink:NamedThing Graph HGNC:8889 biolink:NamedThing Graph HGNC:8896 biolink:NamedThing Graph HGNC:89 biolink:NamedThing Graph HGNC:890 biolink:NamedThing Graph HGNC:8907 biolink:NamedThing Graph HGNC:8910 biolink:NamedThing Graph HGNC:8918 biolink:NamedThing Graph HGNC:8923 biolink:NamedThing Graph HGNC:8925 biolink:NamedThing Graph HGNC:8926 biolink:NamedThing Graph HGNC:8927 biolink:NamedThing Graph HGNC:8931 biolink:NamedThing Graph HGNC:894 biolink:NamedThing Graph HGNC:8940 biolink:NamedThing Graph HGNC:8941 biolink:NamedThing Graph HGNC:8943 biolink:NamedThing Graph HGNC:8950 biolink:NamedThing Graph HGNC:8952 biolink:NamedThing Graph HGNC:8957 biolink:NamedThing Graph HGNC:8959 biolink:NamedThing Graph HGNC:8965 biolink:NamedThing Graph HGNC:8966 biolink:NamedThing Graph HGNC:8967 biolink:NamedThing Graph HGNC:897 biolink:NamedThing Graph HGNC:8975 biolink:NamedThing Graph HGNC:8977 biolink:NamedThing Graph HGNC:8979 biolink:NamedThing Graph HGNC:8980 biolink:NamedThing Graph HGNC:8983 biolink:NamedThing Graph HGNC:8996 biolink:NamedThing Graph HGNC:8999 biolink:NamedThing Graph HGNC:90 biolink:NamedThing Graph HGNC:9004 biolink:NamedThing Graph HGNC:9005 biolink:NamedThing Graph HGNC:9006 biolink:NamedThing Graph HGNC:9008 biolink:NamedThing Graph HGNC:9009 biolink:NamedThing Graph HGNC:9016 biolink:NamedThing Graph HGNC:9020 biolink:NamedThing Graph HGNC:9023 biolink:NamedThing Graph HGNC:9024 biolink:NamedThing Graph HGNC:903 biolink:NamedThing Graph HGNC:9038 biolink:NamedThing Graph HGNC:9039 biolink:NamedThing Graph HGNC:904 biolink:NamedThing Graph HGNC:9040 biolink:NamedThing Graph HGNC:9045 biolink:NamedThing Graph HGNC:9051 biolink:NamedThing Graph HGNC:9052 biolink:NamedThing Graph HGNC:9059 biolink:NamedThing Graph HGNC:9060 biolink:NamedThing Graph HGNC:9066 biolink:NamedThing Graph HGNC:9067 biolink:NamedThing Graph HGNC:9069 biolink:NamedThing Graph HGNC:9071 biolink:NamedThing Graph HGNC:9075 biolink:NamedThing Graph HGNC:9076 biolink:NamedThing Graph HGNC:9080 biolink:NamedThing Graph HGNC:9081 biolink:NamedThing Graph HGNC:9082 biolink:NamedThing Graph HGNC:9083 biolink:NamedThing Graph HGNC:9086 biolink:NamedThing Graph HGNC:91 biolink:NamedThing Graph HGNC:9115 biolink:NamedThing Graph HGNC:9117 biolink:NamedThing Graph HGNC:9118 biolink:NamedThing Graph HGNC:9122 biolink:NamedThing Graph HGNC:914 biolink:NamedThing Graph HGNC:9141 biolink:NamedThing Graph HGNC:9142 biolink:NamedThing Graph HGNC:9143 biolink:NamedThing Graph HGNC:9153 biolink:NamedThing Graph HGNC:9154 biolink:NamedThing Graph HGNC:9155 biolink:NamedThing Graph HGNC:9173 biolink:NamedThing Graph HGNC:9175 biolink:NamedThing Graph HGNC:9177 biolink:NamedThing Graph HGNC:9179 biolink:NamedThing Graph HGNC:9180 biolink:NamedThing Graph HGNC:9181 biolink:NamedThing Graph HGNC:92 biolink:NamedThing Graph HGNC:9201 biolink:NamedThing Graph HGNC:9202 biolink:NamedThing Graph HGNC:9204 biolink:NamedThing Graph HGNC:9208 biolink:NamedThing Graph HGNC:9210 biolink:NamedThing Graph HGNC:9220 biolink:NamedThing Graph HGNC:924 biolink:NamedThing Graph HGNC:9251 biolink:NamedThing Graph HGNC:9255 biolink:NamedThing Graph HGNC:9279 biolink:NamedThing Graph HGNC:93 biolink:NamedThing Graph HGNC:930 biolink:NamedThing Graph HGNC:9302 biolink:NamedThing Graph HGNC:9305 biolink:NamedThing Graph HGNC:9312 biolink:NamedThing Graph HGNC:932 biolink:NamedThing Graph HGNC:9325 biolink:NamedThing Graph HGNC:9330 biolink:NamedThing Graph HGNC:9349 biolink:NamedThing Graph HGNC:9350 biolink:NamedThing Graph HGNC:9359 biolink:NamedThing Graph HGNC:9360 biolink:NamedThing Graph HGNC:9364 biolink:NamedThing Graph HGNC:9380 biolink:NamedThing Graph HGNC:9382 biolink:NamedThing Graph HGNC:9386 biolink:NamedThing Graph HGNC:9388 biolink:NamedThing Graph HGNC:939 biolink:NamedThing Graph HGNC:9399 biolink:NamedThing Graph HGNC:94 biolink:NamedThing Graph HGNC:9402 biolink:NamedThing Graph HGNC:9411 biolink:NamedThing Graph HGNC:9413 biolink:NamedThing Graph HGNC:9414 biolink:NamedThing Graph HGNC:9438 biolink:NamedThing Graph HGNC:9439 biolink:NamedThing Graph HGNC:9446 biolink:NamedThing Graph HGNC:9449 biolink:NamedThing Graph HGNC:9451 biolink:NamedThing Graph HGNC:9453 biolink:NamedThing Graph HGNC:9454 biolink:NamedThing Graph HGNC:9455 biolink:NamedThing Graph HGNC:9456 biolink:NamedThing Graph HGNC:9457 biolink:NamedThing Graph HGNC:9460 biolink:NamedThing Graph HGNC:9462 biolink:NamedThing Graph HGNC:9475 biolink:NamedThing Graph HGNC:9476 biolink:NamedThing Graph HGNC:9477 biolink:NamedThing Graph HGNC:9479 biolink:NamedThing Graph HGNC:9490 biolink:NamedThing Graph HGNC:9498 biolink:NamedThing Graph HGNC:95 biolink:NamedThing Graph HGNC:950 biolink:NamedThing Graph HGNC:9508 biolink:NamedThing Graph HGNC:9509 biolink:NamedThing Graph HGNC:951 biolink:NamedThing Graph HGNC:9545 biolink:NamedThing Graph HGNC:9577 biolink:NamedThing Graph HGNC:9580 biolink:NamedThing Graph HGNC:9585 biolink:NamedThing Graph HGNC:9587 biolink:NamedThing Graph HGNC:9588 biolink:NamedThing Graph HGNC:9591 biolink:NamedThing Graph HGNC:9606 biolink:NamedThing Graph HGNC:9607 biolink:NamedThing Graph HGNC:9608 biolink:NamedThing Graph HGNC:9644 biolink:NamedThing Graph HGNC:9647 biolink:NamedThing Graph HGNC:966 biolink:NamedThing Graph HGNC:9666 biolink:NamedThing Graph HGNC:967 biolink:NamedThing Graph HGNC:9670 biolink:NamedThing Graph HGNC:9678 biolink:NamedThing Graph HGNC:9679 biolink:NamedThing Graph HGNC:9688 biolink:NamedThing Graph HGNC:9689 biolink:NamedThing Graph HGNC:969 biolink:NamedThing Graph HGNC:970 biolink:NamedThing Graph HGNC:9701 biolink:NamedThing Graph HGNC:9706 biolink:NamedThing Graph HGNC:9713 biolink:NamedThing Graph HGNC:9717 biolink:NamedThing Graph HGNC:9719 biolink:NamedThing Graph HGNC:9721 biolink:NamedThing Graph HGNC:9722 biolink:NamedThing Graph HGNC:9725 biolink:NamedThing Graph HGNC:9726 biolink:NamedThing Graph HGNC:9751 biolink:NamedThing Graph HGNC:9752 biolink:NamedThing Graph HGNC:9766 biolink:NamedThing Graph HGNC:9768 biolink:NamedThing Graph HGNC:9788 biolink:NamedThing Graph HGNC:9802 biolink:NamedThing Graph HGNC:9811 biolink:NamedThing Graph HGNC:9816 biolink:NamedThing Graph HGNC:9817 biolink:NamedThing Graph HGNC:9820 biolink:NamedThing Graph HGNC:9823 biolink:NamedThing Graph HGNC:9829 biolink:NamedThing Graph HGNC:9831 biolink:NamedThing Graph HGNC:9834 biolink:NamedThing Graph HGNC:9848 biolink:NamedThing Graph HGNC:986 biolink:NamedThing Graph HGNC:9863 biolink:NamedThing Graph HGNC:9865 biolink:NamedThing Graph HGNC:987 biolink:NamedThing Graph HGNC:9870 biolink:NamedThing Graph HGNC:9871 biolink:NamedThing Graph HGNC:9879 biolink:NamedThing Graph HGNC:9884 biolink:NamedThing Graph HGNC:989 biolink:NamedThing Graph HGNC:9891 biolink:NamedThing Graph HGNC:9896 biolink:NamedThing Graph HGNC:9905 biolink:NamedThing Graph HGNC:9910 biolink:NamedThing Graph HGNC:9921 biolink:NamedThing Graph HGNC:9922 biolink:NamedThing Graph HGNC:9936 biolink:NamedThing Graph HGNC:9940 biolink:NamedThing Graph HGNC:9942 biolink:NamedThing Graph HGNC:9944 biolink:NamedThing Graph HGNC:9949 biolink:NamedThing Graph HGNC:9957 biolink:NamedThing Graph HGNC:9958 biolink:NamedThing Graph HGNC:9964 biolink:NamedThing Graph HGNC:9965 biolink:NamedThing Graph HGNC:9966 biolink:NamedThing Graph HGNC:9967 biolink:NamedThing Graph HGNC:9990 biolink:NamedThing Graph http://loinc.org/rdf/MTHU019741 biolink:mechanism_of_action Graph http://loinc.org/rdf/analyzes biolink:quantifier_qualifier Graph http://loinc.org/rdf/component_of biolink:part_of Graph http://loinc.org/rdf/has_action_guidance biolink:has_attribute Graph http://loinc.org/rdf/has_adjustment biolink:has_attribute Graph http://loinc.org/rdf/has_aggregation_view biolink:has_attribute Graph http://loinc.org/rdf/has_answer biolink:related_to Graph http://loinc.org/rdf/has_approach_guidance biolink:has_attribute Graph http://loinc.org/rdf/has_archetype biolink:subclass_of Graph http://loinc.org/rdf/has_challenge biolink:related_to Graph http://loinc.org/rdf/has_component biolink:has_part Graph http://loinc.org/rdf/has_count biolink:has_count Graph http://loinc.org/rdf/has_divisor biolink:has_attribute Graph http://loinc.org/rdf/has_evaluation biolink:related_to Graph http://loinc.org/rdf/has_exam biolink:has_attribute Graph http://loinc.org/rdf/has_fragments_for_synonyms biolink:has_input Graph http://loinc.org/rdf/has_imaged_location biolink:occurs_in Graph http://loinc.org/rdf/has_imaging_focus biolink:located_in Graph http://loinc.org/rdf/has_lateral_anatomic_location biolink:coexists_with Graph http://loinc.org/rdf/has_lateral_location_presence biolink:coexists_with Graph http://loinc.org/rdf/has_member biolink:has_part Graph http://loinc.org/rdf/has_method biolink:has_attribute Graph http://loinc.org/rdf/has_modality_subtype biolink:has_attribute Graph http://loinc.org/rdf/has_modality_type biolink:has_attribute_type Graph http://loinc.org/rdf/has_object_guidance biolink:has_attribute Graph http://loinc.org/rdf/has_parent_group biolink:subclass_of Graph http://loinc.org/rdf/has_pharmaceutical_route biolink:has_route Graph http://loinc.org/rdf/has_scale biolink:has_attribute Graph http://loinc.org/rdf/has_subject biolink:has_participant Graph http://loinc.org/rdf/has_suffix biolink:has_attribute Graph http://loinc.org/rdf/has_supersystem biolink:part_of Graph http://loinc.org/rdf/has_system biolink:has_input Graph http://loinc.org/rdf/has_time_aspect biolink:has_attribute Graph http://loinc.org/rdf/has_time_modifier biolink:has_attribute Graph http://loinc.org/rdf/has_timing_of biolink:has_attribute Graph http://loinc.org/rdf/has_view_type biolink:has_attribute_type Graph http://loinc.org/rdf/is_given_pharmaceutical_substance_for biolink:participates_in Graph http://loinc.org/rdf/is_presence_guidance_for biolink:subclass_of Graph http://loinc.org/rdf/mapped_to biolink:related_to Graph http://loinc.org/rdf/measured_by biolink:quantifier_qualifier Graph http://loinc.org/rdf/member_of biolink:part_of Graph http://loinc.org/rdf/mth_has_expanded_form biolink:related_to Graph http://loinc.org/rdf/multipart_of biolink:part_of Graph http://loinc.org/rdf/property_of biolink:quantifier_qualifier Graph http://org.semanticweb.owlapi/error#Error1 biolink:NamedThing Graph http://purl.bioontology.org/ontology/STY/T001 biolink:OrganismTaxon Graph http://purl.bioontology.org/ontology/STY/T002 biolink:Plant Graph http://purl.bioontology.org/ontology/STY/T004 biolink:Fungus Graph http://purl.bioontology.org/ontology/STY/T005 biolink:Virus Graph http://purl.bioontology.org/ontology/STY/T007 biolink:Bacterium Graph http://purl.bioontology.org/ontology/STY/T008 biolink:OrganismalEntity Graph http://purl.bioontology.org/ontology/STY/T010 biolink:Vertebrate Graph http://purl.bioontology.org/ontology/STY/T011 biolink:Invertebrate Graph http://purl.bioontology.org/ontology/STY/T015 biolink:Mammal Graph http://purl.bioontology.org/ontology/STY/T016 biolink:Human Graph http://purl.bioontology.org/ontology/STY/T017 biolink:AnatomicalEntity Graph http://purl.bioontology.org/ontology/STY/T018 biolink:GrossAnatomicalStructure Graph http://purl.bioontology.org/ontology/STY/T019 biolink:Disease Graph http://purl.bioontology.org/ontology/STY/T020 biolink:Disease Graph http://purl.bioontology.org/ontology/STY/T023 biolink:GrossAnatomicalStructure Graph http://purl.bioontology.org/ontology/STY/T024 biolink:GrossAnatomicalStructure Graph http://purl.bioontology.org/ontology/STY/T025 biolink:Cell Graph http://purl.bioontology.org/ontology/STY/T026 biolink:CellularComponent Graph http://purl.bioontology.org/ontology/STY/T028 biolink:GenomicEntity Graph http://purl.bioontology.org/ontology/STY/T029 biolink:AnatomicalEntity Graph http://purl.bioontology.org/ontology/STY/T030 biolink:AnatomicalEntity Graph http://purl.bioontology.org/ontology/STY/T031 biolink:AnatomicalEntity Graph http://purl.bioontology.org/ontology/STY/T032 biolink:OrganismAttribute Graph http://purl.bioontology.org/ontology/STY/T033 biolink:DiseaseOrPhenotypicFeature Graph http://purl.bioontology.org/ontology/STY/T034 biolink:Phenomenon Graph http://purl.bioontology.org/ontology/STY/T037 biolink:PathologicalProcess Graph http://purl.bioontology.org/ontology/STY/T038 biolink:Phenomenon Graph http://purl.bioontology.org/ontology/STY/T039 biolink:PhysiologicalProcess Graph http://purl.bioontology.org/ontology/STY/T040 biolink:PhysiologicalProcess Graph http://purl.bioontology.org/ontology/STY/T041 biolink:Behavior Graph http://purl.bioontology.org/ontology/STY/T042 biolink:PhysiologicalProcess Graph http://purl.bioontology.org/ontology/STY/T043 biolink:PhysiologicalProcess Graph http://purl.bioontology.org/ontology/STY/T044 biolink:MolecularActivity Graph http://purl.bioontology.org/ontology/STY/T045 biolink:PhysiologicalProcess Graph http://purl.bioontology.org/ontology/STY/T046 biolink:PathologicalProcess Graph http://purl.bioontology.org/ontology/STY/T047 biolink:Disease Graph http://purl.bioontology.org/ontology/STY/T048 biolink:Disease Graph http://purl.bioontology.org/ontology/STY/T049 biolink:Disease Graph http://purl.bioontology.org/ontology/STY/T050 biolink:BiologicalEntity Graph http://purl.bioontology.org/ontology/STY/T051 biolink:Event Graph http://purl.bioontology.org/ontology/STY/T052 biolink:Activity Graph http://purl.bioontology.org/ontology/STY/T053 biolink:Behavior Graph http://purl.bioontology.org/ontology/STY/T054 biolink:Behavior Graph http://purl.bioontology.org/ontology/STY/T055 biolink:Behavior Graph http://purl.bioontology.org/ontology/STY/T056 biolink:Activity Graph http://purl.bioontology.org/ontology/STY/T057 biolink:Activity Graph http://purl.bioontology.org/ontology/STY/T058 biolink:Activity Graph http://purl.bioontology.org/ontology/STY/T059 biolink:Procedure Graph http://purl.bioontology.org/ontology/STY/T060 biolink:Procedure Graph http://purl.bioontology.org/ontology/STY/T061 biolink:Procedure Graph http://purl.bioontology.org/ontology/STY/T062 biolink:Activity Graph http://purl.bioontology.org/ontology/STY/T063 biolink:Procedure Graph http://purl.bioontology.org/ontology/STY/T064 biolink:Activity Graph http://purl.bioontology.org/ontology/STY/T065 biolink:Activity Graph http://purl.bioontology.org/ontology/STY/T066 biolink:Activity Graph http://purl.bioontology.org/ontology/STY/T069 biolink:Phenomenon Graph http://purl.bioontology.org/ontology/STY/T071 biolink:NamedThing Graph http://purl.bioontology.org/ontology/STY/T072 biolink:PhysicalEntity Graph http://purl.bioontology.org/ontology/STY/T073 biolink:PhysicalEntity Graph http://purl.bioontology.org/ontology/STY/T074 biolink:Device Graph http://purl.bioontology.org/ontology/STY/T075 biolink:Device Graph http://purl.bioontology.org/ontology/STY/T077 biolink:InformationContentEntity Graph http://purl.bioontology.org/ontology/STY/T078 biolink:InformationContentEntity Graph http://purl.bioontology.org/ontology/STY/T079 biolink:InformationContentEntity Graph http://purl.bioontology.org/ontology/STY/T080 biolink:InformationContentEntity Graph http://purl.bioontology.org/ontology/STY/T081 biolink:InformationContentEntity Graph http://purl.bioontology.org/ontology/STY/T082 biolink:InformationContentEntity Graph http://purl.bioontology.org/ontology/STY/T083 biolink:GeographicLocation Graph http://purl.bioontology.org/ontology/STY/T085 biolink:MolecularEntity Graph http://purl.bioontology.org/ontology/STY/T086 biolink:NucleicAcidEntity Graph http://purl.bioontology.org/ontology/STY/T087 biolink:Polypeptide Graph http://purl.bioontology.org/ontology/STY/T088 biolink:MolecularEntity Graph http://purl.bioontology.org/ontology/STY/T089 biolink:InformationContentEntity Graph http://purl.bioontology.org/ontology/STY/T092 biolink:Agent Graph http://purl.bioontology.org/ontology/STY/T093 biolink:Agent Graph http://purl.bioontology.org/ontology/STY/T094 biolink:Agent Graph http://purl.bioontology.org/ontology/STY/T095 biolink:Agent Graph http://purl.bioontology.org/ontology/STY/T096 biolink:Agent Graph http://purl.bioontology.org/ontology/STY/T097 biolink:Cohort Graph http://purl.bioontology.org/ontology/STY/T098 biolink:PopulationOfIndividualOrganisms Graph http://purl.bioontology.org/ontology/STY/T099 biolink:Cohort Graph http://purl.bioontology.org/ontology/STY/T100 biolink:Cohort Graph http://purl.bioontology.org/ontology/STY/T101 biolink:Cohort Graph http://purl.bioontology.org/ontology/STY/T102 biolink:InformationContentEntity Graph http://purl.bioontology.org/ontology/STY/T103 biolink:ChemicalEntity Graph http://purl.bioontology.org/ontology/STY/T109 biolink:SmallMolecule Graph http://purl.bioontology.org/ontology/STY/T110 biolink:SmallMolecule Graph http://purl.bioontology.org/ontology/STY/T111 biolink:SmallMolecule Graph http://purl.bioontology.org/ontology/STY/T114 biolink:NucleicAcidEntity Graph http://purl.bioontology.org/ontology/STY/T115 biolink:SmallMolecule Graph http://purl.bioontology.org/ontology/STY/T116 biolink:Polypeptide Graph http://purl.bioontology.org/ontology/STY/T118 biolink:SmallMolecule Graph http://purl.bioontology.org/ontology/STY/T119 biolink:SmallMolecule Graph http://purl.bioontology.org/ontology/STY/T122 biolink:Device Graph http://purl.bioontology.org/ontology/STY/T123 biolink:SmallMolecule Graph http://purl.bioontology.org/ontology/STY/T124 biolink:SmallMolecule Graph http://purl.bioontology.org/ontology/STY/T125 biolink:SmallMolecule Graph http://purl.bioontology.org/ontology/STY/T126 biolink:Protein Graph http://purl.bioontology.org/ontology/STY/T127 biolink:SmallMolecule Graph http://purl.bioontology.org/ontology/STY/T129 biolink:BiologicalEntity Graph http://purl.bioontology.org/ontology/STY/T130 biolink:DiagnosticAid Graph http://purl.bioontology.org/ontology/STY/T131 biolink:SmallMolecule Graph http://purl.bioontology.org/ontology/STY/T168 biolink:Food Graph http://purl.bioontology.org/ontology/STY/T169 biolink:InformationContentEntity Graph http://purl.bioontology.org/ontology/STY/T170 biolink:Publication Graph http://purl.bioontology.org/ontology/STY/T171 biolink:InformationContentEntity Graph http://purl.bioontology.org/ontology/STY/T184 biolink:PhenotypicFeature Graph http://purl.bioontology.org/ontology/STY/T185 biolink:InformationContentEntity Graph http://purl.bioontology.org/ontology/STY/T190 biolink:Disease Graph http://purl.bioontology.org/ontology/STY/T191 biolink:Disease Graph http://purl.bioontology.org/ontology/STY/T192 biolink:Protein Graph http://purl.bioontology.org/ontology/STY/T195 biolink:Drug Graph http://purl.bioontology.org/ontology/STY/T196 biolink:SmallMolecule Graph http://purl.bioontology.org/ontology/STY/T197 biolink:SmallMolecule Graph http://purl.bioontology.org/ontology/STY/T200 biolink:Drug Graph http://purl.bioontology.org/ontology/STY/T201 biolink:ClinicalAttribute Graph http://purl.bioontology.org/ontology/STY/T203 biolink:Device Graph http://purl.org/spar/fabio/JournalArticle biolink:JournalArticle Graph http://purl.org/spar/fabio/Patent biolink:Patent Graph http://purl.org/spar/fabio/Preprint biolink:PreprintPublication Graph http://purl.org/spar/fabio/WebPage biolink:WebPage Graph http://purl.org/spar/fabio/article biolink:Article Graph http://qudt.org/1.1/schema/qudt#quantityValue biolink:has_quantitative_value Graph http://qudt.org/1.1/schema/qudt#unit biolink:has_unit Graph http://schema.org/Class biolink:NamedThing Graph http://schema.org/dataset biolink:Dataset Graph http://smpdb.ca/pathways/#has_bound biolink:has_participant Graph http://smpdb.ca/pathways/#has_compound biolink:has_participant Graph http://smpdb.ca/pathways/#has_element_collection biolink:has_participant Graph http://smpdb.ca/pathways/#has_element_in_bound biolink:has_part Graph http://smpdb.ca/pathways/#has_enzyme biolink:has_participant Graph http://smpdb.ca/pathways/#has_left_element biolink:has_input Graph http://smpdb.ca/pathways/#has_location biolink:occurs_in Graph http://smpdb.ca/pathways/#has_nucleic_acid biolink:has_participant Graph http://smpdb.ca/pathways/#has_protein biolink:has_participant Graph http://smpdb.ca/pathways/#has_protein_in_complex biolink:has_part Graph http://smpdb.ca/pathways/#has_reaction biolink:has_participant Graph http://smpdb.ca/pathways/#has_right_element biolink:has_output Graph http://smpdb.ca/pathways/#in_species biolink:occurs_in Graph http://snomed.info/id/32485007 biolink:Hospitalization Graph http://snomed.info/id/418038007 biolink:associated_with_sensitivity_to Graph http://snomed.info/id/47429007 biolink:associated_with Graph http://snomed.info/id/49616005 biolink:ChemicalMixture Graph http://snomed.info/id/8116006 biolink:PhenotypicFeature Graph http://translator.renci.org/ubergraph-axioms.ofn#is_decrease_of biolink:affects Graph http://translator.renci.org/ubergraph-axioms.ofn#is_increase_of biolink:affects Graph http://www.ebi.ac.uk/ancestro/ancestro_0301 biolink:has_attribute Graph http://www.ebi.ac.uk/ancestro/ancestro_0308 biolink:has_attribute Graph http://www.ebi.ac.uk/ancestro/ancestro_0330 biolink:synonym Graph http://www.ebi.ac.uk/efo/EFO_0000784 biolink:located_in Graph http://www.ebi.ac.uk/efo/EFO_0001444 biolink:ClinicalMeasurement Graph http://www.ebi.ac.uk/efo/EFO_0006351 biolink:related_to Graph http://www.ebi.ac.uk/efo/EFO_0009708 biolink:PathologicalProcess Graph http://www.ebi.ac.uk/efo/EFO_0010558 biolink:PreprintPublication Graph http://www.ebi.ac.uk/efo/EFO_is_executed_in biolink:has_attribute Graph http://www.w3.org/2003/01/geo/wgs84_poslat biolink:latitude Graph http://www.w3.org/2003/01/geo/wgs84_poslong biolink:longitude Graph https://bioschemas.org/ChemicalSubstance biolink:SmallMolecule Graph https://bioschemas.org/MolecularEntity biolink:MolecularEntity Graph https://bioschemas.org/Taxon biolink:OrganismTaxon Graph https://bioschemas.org/gene biolink:Gene Graph https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#Alias biolink:synonym Graph https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#Dbxref biolink:xref Graph https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#ID biolink:id Graph https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#end biolink:end_coordinate Graph https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#phase biolink:phase Graph https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#start biolink:start_coordinate Graph https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md#strand biolink:strand Graph https://github.com/cmungall/owlstar/blob/master/owlstar.ttlAllSomeInterpretation biolink:NamedThing Graph https://github.com/cmungall/owlstar/blob/master/owlstar.ttlLogicalInterpretation biolink:logical_interpretation Graph https://github.com/cmungall/owlstar/blob/master/owlstar.ttlSomeSomeInterpretation biolink:NamedThing Graph https://github.com/ga4gh/vr-spec/Haplotype biolink:Haplotype Graph https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_ID biolink:id Graph https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_Symbol biolink:symbol Graph https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Object_Synonyms biolink:synonym Graph https://github.com/geneontology/go-annotation/blob/master/specs/gpad-gpi-2-0.md#DB_Xrefs biolink:xref Graph https://lhncbc.nlm.nih.gov/semanticnetwork/download/sg_archive/SemGroups-v04.txtACTI biolink:ActivityAndBehavior Graph https://lhncbc.nlm.nih.gov/semanticnetwork/download/sg_archive/SemGroups-v04.txtANAT biolink:AnatomicalEntity Graph https://lhncbc.nlm.nih.gov/semanticnetwork/download/sg_archive/SemGroups-v04.txtCONC biolink:InformationContentEntity Graph https://lhncbc.nlm.nih.gov/semanticnetwork/download/sg_archive/SemGroups-v04.txtDEVI biolink:Device Graph https://lhncbc.nlm.nih.gov/semanticnetwork/download/sg_archive/SemGroups-v04.txtDISO biolink:Disease Graph https://lhncbc.nlm.nih.gov/semanticnetwork/download/sg_archive/SemGroups-v04.txtGEOG biolink:GeographicLocation Graph https://lhncbc.nlm.nih.gov/semanticnetwork/download/sg_archive/SemGroups-v04.txtLIVB biolink:OrganismalEntity Graph https://lhncbc.nlm.nih.gov/semanticnetwork/download/sg_archive/SemGroups-v04.txtOBJC biolink:NamedThing Graph https://lhncbc.nlm.nih.gov/semanticnetwork/download/sg_archive/SemGroups-v04.txtORGA biolink:Agent Graph https://lhncbc.nlm.nih.gov/semanticnetwork/download/sg_archive/SemGroups-v04.txtPHEN biolink:Phenomenon Graph https://lhncbc.nlm.nih.gov/semanticnetwork/download/sg_archive/SemGroups-v04.txtPROC biolink:Procedure Graph https://skr3.nlm.nih.gov/SemMedDBADMINISTERED_TO biolink:related_to Graph https://skr3.nlm.nih.gov/SemMedDBAFFECTS biolink:affects Graph https://skr3.nlm.nih.gov/SemMedDBASSOCIATED_WITH biolink:related_to Graph https://skr3.nlm.nih.gov/SemMedDBCAUSES biolink:causes Graph https://skr3.nlm.nih.gov/SemMedDBCONVERTS_TO biolink:derives_into Graph https://skr3.nlm.nih.gov/SemMedDBDIAGNOSES biolink:diagnoses Graph https://skr3.nlm.nih.gov/SemMedDBDISRUPTS biolink:disrupts Graph https://skr3.nlm.nih.gov/SemMedDBINTERACTS_WITH biolink:interacts_with Graph https://skr3.nlm.nih.gov/SemMedDBISA biolink:subclass_of Graph https://skr3.nlm.nih.gov/SemMedDBLOCATION_OF biolink:location_of Graph https://skr3.nlm.nih.gov/SemMedDBMANIFESTATION_OF biolink:manifestation_of Graph https://skr3.nlm.nih.gov/SemMedDBMEASURES biolink:quantifier_qualifier Graph https://skr3.nlm.nih.gov/SemMedDBOCCURS_IN biolink:occurs_in Graph https://skr3.nlm.nih.gov/SemMedDBPART_OF biolink:part_of Graph https://skr3.nlm.nih.gov/SemMedDBPRECEDES biolink:precedes Graph https://skr3.nlm.nih.gov/SemMedDBPREDISPOSES biolink:predisposes Graph https://skr3.nlm.nih.gov/SemMedDBPREVENTS biolink:prevents Graph https://skr3.nlm.nih.gov/SemMedDBPROCESS_OF biolink:occurs_in Graph https://skr3.nlm.nih.gov/SemMedDBPRODUCES biolink:produces Graph https://skr3.nlm.nih.gov/SemMedDBTREATS biolink:treats Graph https://skr3.nlm.nih.gov/SemMedDBUSES biolink:has_input Graph https://skr3.nlm.nih.gov/SemMedDBcompared_with biolink:related_to Graph https://skr3.nlm.nih.gov/SemMedDBhigher_than biolink:related_to Graph https://skr3.nlm.nih.gov/SemMedDBlower_than biolink:related_to Graph https://skr3.nlm.nih.gov/SemMedDBsame_as biolink:close_match Graph biolink:AccessibleDnaRegion biolink:NamedThing Graph biolink:Activity biolink:NamedThing Graph biolink:ActivityAndBehavior biolink:NamedThing Graph biolink:AdministrativeEntity biolink:NamedThing Graph biolink:Agent biolink:NamedThing Graph biolink:AnatomicalEntity biolink:NamedThing Graph biolink:AnatomicalEntityToAnatomicalEntityAssociation biolink:NamedThing Graph biolink:AnatomicalEntityToAnatomicalEntityOntogenicAssociation biolink:NamedThing Graph biolink:AnatomicalEntityToAnatomicalEntityPartOfAssociation biolink:NamedThing Graph biolink:Annotation biolink:NamedThing Graph biolink:Article biolink:NamedThing Graph biolink:Association biolink:NamedThing Graph biolink:Attribute biolink:NamedThing Graph biolink:Bacterium biolink:NamedThing Graph biolink:Behavior biolink:NamedThing Graph biolink:BehaviorToBehavioralFeatureAssociation biolink:NamedThing Graph biolink:BehavioralExposure biolink:NamedThing Graph biolink:BehavioralFeature biolink:NamedThing Graph biolink:BehavioralOutcome biolink:NamedThing Graph biolink:BiologicalEntity biolink:NamedThing Graph biolink:BiologicalProcess biolink:NamedThing Graph biolink:BiologicalProcessOrActivity biolink:NamedThing Graph biolink:BiologicalSequence biolink:NamedThing Graph biolink:BiologicalSex biolink:NamedThing Graph biolink:BioticExposure biolink:NamedThing Graph biolink:Book biolink:NamedThing Graph biolink:BookChapter biolink:NamedThing Graph biolink:Case biolink:NamedThing Graph biolink:CaseToEntityAssociationMixin biolink:NamedThing Graph biolink:CaseToPhenotypicFeatureAssociation biolink:NamedThing Graph biolink:CategoryType biolink:NamedThing Graph biolink:CausalGeneToDiseaseAssociation biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum biolink:NamedThing Graph biolink:Cell biolink:NamedThing Graph biolink:CellLine biolink:NamedThing Graph biolink:CellLineAsAModelOfDiseaseAssociation biolink:NamedThing Graph biolink:CellLineToDiseaseOrPhenotypicFeatureAssociation biolink:NamedThing Graph biolink:CellLineToEntityAssociationMixin biolink:NamedThing Graph biolink:CellularComponent biolink:NamedThing Graph biolink:CellularOrganism biolink:NamedThing Graph biolink:ChemicalAffectsGeneAssociation biolink:NamedThing Graph biolink:ChemicalEntity biolink:NamedThing Graph biolink:ChemicalEntityAssessesNamedThingAssociation biolink:NamedThing Graph biolink:ChemicalEntityDerivativeEnum biolink:NamedThing Graph biolink:ChemicalEntityOrGeneOrGeneProduct biolink:NamedThing Graph biolink:ChemicalEntityOrGeneOrGeneProductRegulatesGeneAssociation biolink:NamedThing Graph biolink:ChemicalEntityOrProteinOrPolypeptide biolink:NamedThing Graph biolink:ChemicalEntityToEntityAssociationMixin biolink:NamedThing Graph biolink:ChemicalExposure biolink:NamedThing Graph biolink:ChemicalFormulaValue biolink:NamedThing Graph biolink:ChemicalGeneInteractionAssociation biolink:NamedThing Graph biolink:ChemicalMixture biolink:NamedThing Graph biolink:ChemicalOrDrugOrTreatment biolink:NamedThing Graph biolink:ChemicalOrDrugOrTreatmentSideEffectDiseaseOrPhenotypicFeatureAssociation biolink:NamedThing Graph biolink:ChemicalOrDrugOrTreatmentToDiseaseOrPhenotypicFeatureAssociation biolink:NamedThing Graph biolink:ChemicalOrGeneOrGeneProductFormOrVariantEnum biolink:NamedThing Graph biolink:ChemicalRole biolink:NamedThing Graph biolink:ChemicalToChemicalAssociation biolink:NamedThing Graph biolink:ChemicalToChemicalDerivationAssociation biolink:NamedThing Graph biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation biolink:NamedThing Graph biolink:ChemicalToEntityAssociationMixin biolink:NamedThing Graph biolink:ChemicalToPathwayAssociation biolink:NamedThing Graph biolink:ChiSquaredAnalysisResult biolink:NamedThing Graph biolink:ClinicalAttribute biolink:NamedThing Graph biolink:ClinicalCourse biolink:NamedThing Graph biolink:ClinicalEntity biolink:NamedThing Graph biolink:ClinicalFinding biolink:NamedThing Graph biolink:ClinicalIntervention biolink:NamedThing Graph biolink:ClinicalMeasurement biolink:NamedThing Graph biolink:ClinicalModifier biolink:NamedThing Graph biolink:ClinicalTrial biolink:NamedThing Graph biolink:CodingSequence biolink:NamedThing Graph biolink:Cohort biolink:NamedThing Graph biolink:CommonDataElement biolink:NamedThing Graph biolink:ComplexChemicalExposure biolink:NamedThing Graph biolink:ComplexMolecularMixture biolink:NamedThing Graph biolink:ConceptCountAnalysisResult biolink:NamedThing Graph biolink:ConfidenceLevel biolink:NamedThing Graph biolink:ContributorAssociation biolink:NamedThing Graph biolink:CorrelatedGeneToDiseaseAssociation biolink:NamedThing Graph biolink:Dataset biolink:NamedThing Graph biolink:DatasetDistribution biolink:NamedThing Graph biolink:DatasetSummary biolink:NamedThing Graph biolink:DatasetVersion biolink:NamedThing Graph biolink:Device biolink:NamedThing Graph biolink:DiagnosticAid biolink:NamedThing Graph biolink:DirectionQualifierEnum biolink:NamedThing Graph biolink:Disease biolink:NamedThing Graph biolink:DiseaseOrPhenotypicFeature biolink:NamedThing Graph biolink:DiseaseOrPhenotypicFeatureExposure biolink:NamedThing Graph biolink:DiseaseOrPhenotypicFeatureOutcome biolink:NamedThing Graph biolink:DiseaseOrPhenotypicFeatureToEntityAssociationMixin biolink:NamedThing Graph biolink:DiseaseOrPhenotypicFeatureToGeneticInheritanceAssociation biolink:NamedThing Graph biolink:DiseaseOrPhenotypicFeatureToLocationAssociation biolink:NamedThing Graph biolink:DiseaseToEntityAssociationMixin biolink:NamedThing Graph biolink:DiseaseToExposureEventAssociation biolink:NamedThing Graph biolink:DiseaseToPhenotypicFeatureAssociation biolink:NamedThing Graph biolink:Drug biolink:NamedThing Graph biolink:DrugAvailabilityEnum biolink:NamedThing Graph biolink:DrugDeliveryEnum biolink:NamedThing Graph biolink:DrugExposure biolink:NamedThing Graph biolink:DrugLabel biolink:NamedThing Graph biolink:DrugToEntityAssociationMixin biolink:NamedThing Graph biolink:DrugToGeneAssociation biolink:NamedThing Graph biolink:DrugToGeneInteractionExposure biolink:NamedThing Graph biolink:DruggableGeneCategoryEnum biolink:NamedThing Graph biolink:DruggableGeneToDiseaseAssociation biolink:NamedThing Graph biolink:Entity biolink:NamedThing Graph biolink:EntityToDiseaseAssociation biolink:NamedThing Graph biolink:EntityToDiseaseAssociationMixin biolink:NamedThing Graph biolink:EntityToDiseaseOrPhenotypicFeatureAssociationMixin biolink:NamedThing Graph biolink:EntityToExposureEventAssociationMixin biolink:NamedThing Graph biolink:EntityToFeatureOrDiseaseQualifiersMixin biolink:NamedThing Graph biolink:EntityToOutcomeAssociationMixin biolink:NamedThing Graph biolink:EntityToPhenotypicFeatureAssociation biolink:NamedThing Graph biolink:EntityToPhenotypicFeatureAssociationMixin biolink:NamedThing Graph biolink:EnvironmentalExposure biolink:NamedThing Graph biolink:EnvironmentalFeature biolink:NamedThing Graph biolink:EnvironmentalFoodContaminant biolink:NamedThing Graph biolink:EnvironmentalProcess biolink:NamedThing Graph biolink:EpidemiologicalOutcome biolink:NamedThing Graph biolink:EpigenomicEntity biolink:NamedThing Graph biolink:Event biolink:NamedThing Graph biolink:EvidenceType biolink:NamedThing Graph biolink:Exon biolink:NamedThing Graph biolink:ExonToTranscriptRelationship biolink:NamedThing Graph biolink:ExposureEvent biolink:NamedThing Graph biolink:ExposureEventToOutcomeAssociation biolink:NamedThing Graph biolink:ExposureEventToPhenotypicFeatureAssociation biolink:NamedThing Graph biolink:FDAApprovalStatusEnum biolink:NamedThing Graph biolink:FDAIDAAdverseEventEnum biolink:NamedThing Graph biolink:Food biolink:NamedThing Graph biolink:FoodAdditive biolink:NamedThing Graph biolink:FrequencyQualifierMixin biolink:NamedThing Graph biolink:FrequencyQuantifier biolink:NamedThing Graph biolink:FrequencyValue biolink:NamedThing Graph biolink:FunctionalAssociation biolink:NamedThing Graph biolink:Fungus biolink:NamedThing Graph biolink:Gene biolink:NamedThing Graph biolink:GeneAffectsChemicalAssociation biolink:NamedThing Graph biolink:GeneAsAModelOfDiseaseAssociation biolink:NamedThing Graph biolink:GeneExpressionMixin biolink:NamedThing Graph biolink:GeneFamily biolink:NamedThing Graph biolink:GeneGroupingMixin biolink:NamedThing Graph biolink:GeneHasVariantThatContributesToDiseaseAssociation biolink:NamedThing Graph biolink:GeneOrGeneProduct biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalPartQualifierEnum biolink:NamedThing Graph biolink:GeneProductIsoformMixin biolink:NamedThing Graph biolink:GeneProductMixin biolink:NamedThing Graph biolink:GeneToDiseaseAssociation biolink:NamedThing Graph biolink:GeneToDiseaseOrPhenotypicFeatureAssociation biolink:NamedThing Graph biolink:GeneToEntityAssociationMixin biolink:NamedThing Graph biolink:GeneToExpressionSiteAssociation biolink:NamedThing Graph biolink:GeneToGeneAssociation biolink:NamedThing Graph biolink:GeneToGeneCoexpressionAssociation biolink:NamedThing Graph biolink:GeneToGeneFamilyAssociation biolink:NamedThing Graph biolink:GeneToGeneHomologyAssociation biolink:NamedThing Graph biolink:GeneToGeneProductRelationship biolink:NamedThing Graph biolink:GeneToGoTermAssociation biolink:NamedThing Graph biolink:GeneToPathwayAssociation biolink:NamedThing Graph biolink:GeneToPhenotypicFeatureAssociation biolink:NamedThing Graph biolink:GeneticInheritance biolink:NamedThing Graph biolink:Genome biolink:NamedThing Graph biolink:GenomicBackgroundExposure biolink:NamedThing Graph biolink:GenomicEntity biolink:NamedThing Graph biolink:GenomicSequenceLocalization biolink:NamedThing Graph biolink:Genotype biolink:NamedThing Graph biolink:GenotypeAsAModelOfDiseaseAssociation biolink:NamedThing Graph biolink:GenotypeToDiseaseAssociation biolink:NamedThing Graph biolink:GenotypeToEntityAssociationMixin biolink:NamedThing Graph biolink:GenotypeToGeneAssociation biolink:NamedThing Graph biolink:GenotypeToGenotypePartAssociation biolink:NamedThing Graph biolink:GenotypeToPhenotypicFeatureAssociation biolink:NamedThing Graph biolink:GenotypeToVariantAssociation biolink:NamedThing Graph biolink:GenotypicSex biolink:NamedThing Graph biolink:GeographicExposure biolink:NamedThing Graph biolink:GeographicLocation biolink:NamedThing Graph biolink:GeographicLocationAtTime biolink:NamedThing Graph biolink:GrossAnatomicalStructure biolink:NamedThing Graph biolink:Haplotype biolink:NamedThing Graph biolink:Hospitalization biolink:NamedThing Graph biolink:HospitalizationOutcome biolink:NamedThing Graph biolink:Human biolink:NamedThing Graph biolink:IndividualOrganism biolink:NamedThing Graph biolink:InformationContentEntity biolink:NamedThing Graph biolink:InformationContentEntityToNamedThingAssociation biolink:NamedThing Graph biolink:Invertebrate biolink:NamedThing Graph biolink:IriType biolink:NamedThing Graph biolink:JournalArticle biolink:NamedThing Graph biolink:LabelType biolink:NamedThing Graph biolink:LifeStage biolink:NamedThing Graph biolink:LogOddsAnalysisResult biolink:NamedThing Graph biolink:LogicalInterpretationEnum biolink:NamedThing Graph biolink:MacromolecularComplex biolink:NamedThing Graph biolink:MacromolecularMachineMixin biolink:NamedThing Graph biolink:MacromolecularMachineToBiologicalProcessAssociation biolink:NamedThing Graph biolink:MacromolecularMachineToCellularComponentAssociation biolink:NamedThing Graph biolink:MacromolecularMachineToEntityAssociationMixin biolink:NamedThing Graph biolink:MacromolecularMachineToMolecularActivityAssociation biolink:NamedThing Graph biolink:Mammal biolink:NamedThing Graph biolink:MappingCollection biolink:NamedThing Graph biolink:MaterialSample biolink:NamedThing Graph biolink:MaterialSampleDerivationAssociation biolink:NamedThing Graph biolink:MaterialSampleToDiseaseOrPhenotypicFeatureAssociation biolink:NamedThing Graph biolink:MaterialSampleToEntityAssociationMixin biolink:NamedThing Graph biolink:MicroRNA biolink:NamedThing Graph biolink:ModelToDiseaseAssociationMixin biolink:NamedThing Graph biolink:MolecularActivity biolink:NamedThing Graph biolink:MolecularActivityToChemicalEntityAssociation biolink:NamedThing Graph biolink:MolecularActivityToMolecularActivityAssociation biolink:NamedThing Graph biolink:MolecularActivityToPathwayAssociation biolink:NamedThing Graph biolink:MolecularEntity biolink:NamedThing Graph biolink:MolecularMixture biolink:NamedThing Graph biolink:MortalityOutcome biolink:NamedThing Graph biolink:NamedThing biolink:NamedThing Graph biolink:NamedThingAssociatedWithLikelihoodOfNamedThingAssociation biolink:NamedThing Graph biolink:NarrativeText biolink:NamedThing Graph biolink:NoncodingRNAProduct biolink:NamedThing Graph biolink:NucleicAcidEntity biolink:NamedThing Graph biolink:NucleicAcidSequenceMotif biolink:NamedThing Graph biolink:NucleosomeModification biolink:NamedThing Graph biolink:ObservedExpectedFrequencyAnalysisResult biolink:NamedThing Graph biolink:Occurrent biolink:NamedThing Graph biolink:Onset biolink:NamedThing Graph biolink:OntologyClass biolink:NamedThing Graph biolink:OrganismAttribute biolink:NamedThing Graph biolink:OrganismTaxon biolink:NamedThing Graph biolink:OrganismTaxonToEntityAssociation biolink:NamedThing Graph biolink:OrganismTaxonToEnvironmentAssociation biolink:NamedThing Graph biolink:OrganismTaxonToOrganismTaxonAssociation biolink:NamedThing Graph biolink:OrganismTaxonToOrganismTaxonInteraction biolink:NamedThing Graph biolink:OrganismTaxonToOrganismTaxonSpecialization biolink:NamedThing Graph biolink:OrganismToOrganismAssociation biolink:NamedThing Graph biolink:OrganismalEntity biolink:NamedThing Graph biolink:OrganismalEntityAsAModelOfDiseaseAssociation biolink:NamedThing Graph biolink:Outcome biolink:NamedThing Graph biolink:PairwiseGeneToGeneInteraction biolink:NamedThing Graph biolink:PairwiseMolecularInteraction biolink:NamedThing Graph biolink:Patent biolink:NamedThing Graph biolink:PathognomonicityQuantifier biolink:NamedThing Graph biolink:PathologicalAnatomicalExposure biolink:NamedThing Graph biolink:PathologicalAnatomicalOutcome biolink:NamedThing Graph biolink:PathologicalAnatomicalStructure biolink:NamedThing Graph biolink:PathologicalEntityMixin biolink:NamedThing Graph biolink:PathologicalProcess biolink:NamedThing Graph biolink:PathologicalProcessExposure biolink:NamedThing Graph biolink:PathologicalProcessOutcome biolink:NamedThing Graph biolink:Pathway biolink:NamedThing Graph biolink:PercentageFrequencyValue biolink:NamedThing Graph biolink:PhaseEnum biolink:NamedThing Graph biolink:Phenomenon biolink:NamedThing Graph biolink:PhenotypicFeature biolink:NamedThing Graph biolink:PhenotypicQuality biolink:NamedThing Graph biolink:PhenotypicSex biolink:NamedThing Graph biolink:PhysicalEntity biolink:NamedThing Graph biolink:PhysicalEssence biolink:NamedThing Graph biolink:PhysicalEssenceOrOccurrent biolink:NamedThing Graph biolink:PhysiologicalProcess biolink:NamedThing Graph biolink:PlanetaryEntity biolink:NamedThing Graph biolink:Plant biolink:NamedThing Graph biolink:Polypeptide biolink:NamedThing Graph biolink:PopulationOfIndividualOrganisms biolink:NamedThing Graph biolink:PopulationToPopulationAssociation biolink:NamedThing Graph biolink:PosttranslationalModification biolink:NamedThing Graph biolink:PredicateMapping biolink:NamedThing Graph biolink:PredicateType biolink:NamedThing Graph biolink:PreprintPublication biolink:NamedThing Graph biolink:Procedure biolink:NamedThing Graph biolink:ProcessedMaterial biolink:NamedThing Graph biolink:Protein biolink:NamedThing Graph biolink:ProteinDomain biolink:NamedThing Graph biolink:ProteinFamily biolink:NamedThing Graph biolink:ProteinIsoform biolink:NamedThing Graph biolink:Publication biolink:NamedThing Graph biolink:QuantityValue biolink:NamedThing Graph biolink:Quotient biolink:NamedThing Graph biolink:RNAProduct biolink:NamedThing Graph biolink:RNAProductIsoform biolink:NamedThing Graph biolink:ReactionDirectionEnum biolink:NamedThing Graph biolink:ReactionSideEnum biolink:NamedThing Graph biolink:ReactionToCatalystAssociation biolink:NamedThing Graph biolink:ReactionToParticipantAssociation biolink:NamedThing Graph biolink:ReagentTargetedGene biolink:NamedThing Graph biolink:RegulatoryRegion biolink:NamedThing Graph biolink:RelationshipQuantifier biolink:NamedThing Graph biolink:RelationshipType biolink:NamedThing Graph biolink:RelativeFrequencyAnalysisResult biolink:NamedThing Graph biolink:ResourceRoleEnum biolink:NamedThing Graph biolink:RetrievalSource biolink:NamedThing Graph biolink:SensitivityQuantifier biolink:NamedThing Graph biolink:SequenceAssociation biolink:NamedThing Graph biolink:SequenceEnum biolink:NamedThing Graph biolink:SequenceFeatureRelationship biolink:NamedThing Graph biolink:SequenceVariant biolink:NamedThing Graph biolink:SequenceVariantModulatesTreatmentAssociation biolink:NamedThing Graph biolink:Serial biolink:NamedThing Graph biolink:SeverityValue biolink:NamedThing Graph biolink:SiRNA biolink:NamedThing Graph biolink:SmallMolecule biolink:NamedThing Graph biolink:Snv biolink:NamedThing Graph biolink:SocioeconomicAttribute biolink:NamedThing Graph biolink:SocioeconomicExposure biolink:NamedThing Graph biolink:SocioeconomicOutcome biolink:NamedThing Graph biolink:SpecificityQuantifier biolink:NamedThing Graph biolink:StrandEnum biolink:NamedThing Graph biolink:Study biolink:NamedThing Graph biolink:StudyPopulation biolink:NamedThing Graph biolink:StudyResult biolink:NamedThing Graph biolink:StudyVariable biolink:NamedThing Graph biolink:SubjectOfInvestigation biolink:NamedThing Graph biolink:SymbolType biolink:NamedThing Graph biolink:TaxonToTaxonAssociation biolink:NamedThing Graph biolink:TaxonomicRank biolink:NamedThing Graph biolink:TextMiningResult biolink:NamedThing Graph biolink:ThingWithTaxon biolink:NamedThing Graph biolink:TimeType biolink:NamedThing Graph biolink:Transcript biolink:NamedThing Graph biolink:TranscriptToGeneRelationship biolink:NamedThing Graph biolink:TranscriptionFactorBindingSite biolink:NamedThing Graph biolink:Treatment biolink:NamedThing Graph biolink:Unit biolink:NamedThing Graph biolink:VariantAsAModelOfDiseaseAssociation biolink:NamedThing Graph biolink:VariantToDiseaseAssociation biolink:NamedThing Graph biolink:VariantToEntityAssociationMixin biolink:NamedThing Graph biolink:VariantToGeneAssociation biolink:NamedThing Graph biolink:VariantToGeneExpressionAssociation biolink:NamedThing Graph biolink:VariantToPhenotypicFeatureAssociation biolink:NamedThing Graph biolink:VariantToPopulationAssociation biolink:NamedThing Graph biolink:Vertebrate biolink:NamedThing Graph biolink:Virus biolink:NamedThing Graph biolink:WebPage biolink:NamedThing Graph biolink:Zygosity biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#activation biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#agonism biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#antagonism biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#antibody_inhibition biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#binding biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#inducer biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#inhibition biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#inverse_agonism biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#molecular_channel_blockage biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#molecular_channel_opening biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#negative_allosteric_modulation biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#positive_allosteric_modulation biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#potentiation biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#releasing_activity biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#signaling_mediated_control biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#stabilization biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#stimulation biolink:NamedThing Graph biolink:CausalMechanismQualifierEnum#transcriptional_regulation biolink:NamedThing Graph biolink:ChemicalEntityDerivativeEnum#metabolite biolink:NamedThing Graph biolink:ChemicalOrGeneOrGeneProductFormOrVariantEnum#analog_form biolink:NamedThing Graph biolink:ChemicalOrGeneOrGeneProductFormOrVariantEnum#gain_of_function_variant_form biolink:NamedThing Graph biolink:ChemicalOrGeneOrGeneProductFormOrVariantEnum#genetic_variant_form biolink:NamedThing Graph biolink:ChemicalOrGeneOrGeneProductFormOrVariantEnum#loss_of_function_variant_form biolink:NamedThing Graph biolink:ChemicalOrGeneOrGeneProductFormOrVariantEnum#modified_form biolink:NamedThing Graph biolink:ChemicalOrGeneOrGeneProductFormOrVariantEnum#polymorphic_form biolink:NamedThing Graph biolink:ChemicalOrGeneOrGeneProductFormOrVariantEnum#snp_form biolink:NamedThing Graph biolink:DirectionQualifierEnum#decreased biolink:NamedThing Graph biolink:DirectionQualifierEnum#downregulated biolink:NamedThing Graph biolink:DirectionQualifierEnum#increased biolink:NamedThing Graph biolink:DirectionQualifierEnum#upregulated biolink:NamedThing Graph biolink:DrugAvailabilityEnum#over_the_counter biolink:NamedThing Graph biolink:DrugAvailabilityEnum#prescription biolink:NamedThing Graph biolink:DrugDeliveryEnum#absorption_through_the_skin biolink:NamedThing Graph biolink:DrugDeliveryEnum#inhalation biolink:NamedThing Graph biolink:DrugDeliveryEnum#intravenous_injection biolink:NamedThing Graph biolink:DrugDeliveryEnum#oral biolink:NamedThing Graph biolink:DruggableGeneCategoryEnum#tbio biolink:NamedThing Graph biolink:DruggableGeneCategoryEnum#tchem biolink:NamedThing Graph biolink:DruggableGeneCategoryEnum#tclin biolink:NamedThing Graph biolink:DruggableGeneCategoryEnum#tdark biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#discovery_and_development_phase biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#fda_accelerated_approval biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#fda_breakthrough_therapy biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#fda_clinical_research_phase biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#fda_clinical_research_phase_1 biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#fda_clinical_research_phase_2 biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#fda_clinical_research_phase_3 biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#fda_clinical_research_phase_4 biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#fda_fast_track biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#fda_post_market_safety_review biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#fda_priority_review biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#fda_review_phase_4 biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#post_approval_withdrawal biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#preclinical_research_phase biolink:NamedThing Graph biolink:FDAApprovalStatusEnum#regular_fda_approval biolink:NamedThing Graph biolink:FDAIDAAdverseEventEnum#life_threatening_adverse_event biolink:NamedThing Graph biolink:FDAIDAAdverseEventEnum#serious_adverse_event biolink:NamedThing Graph biolink:FDAIDAAdverseEventEnum#suspected_adverse_reaction biolink:NamedThing Graph biolink:FDAIDAAdverseEventEnum#unexpected_adverse_event biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#ADP-ribosylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#abundance biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#acetylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#activity biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#activity_or_abundance biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#acylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#alkylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#amination biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#carbamoylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#carboxylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#cleavage biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#degradation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#ethylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#expression biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#farnesylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#folding biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#geranoylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#glucuronidation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#glutathionylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#glycation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#glycosylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#hydrolysis biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#hydroxylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#lipidation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#localization biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#metabolic_processing biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#methylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#molecular_interaction biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#molecular_modification biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#mutation_rate biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#myristoylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#n_linked_glycosylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#nitrosation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#nucleotidylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#o_linked_glycosylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#oxidation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#palmitoylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#phosphorylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#prenylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#reduction biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#ribosylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#secretion biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#splicing biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#stability biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#sulfation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#sumoylation biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#synthesis biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#transport biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#ubiquitination biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalEntityAspectEnum#uptake biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalPartQualifierEnum#enhancer biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalPartQualifierEnum#exon biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalPartQualifierEnum#intron biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalPartQualifierEnum#polya_tail biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalPartQualifierEnum#promoter biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalPartQualifierEnum#3_prime_utr biolink:NamedThing Graph biolink:GeneOrGeneProductOrChemicalPartQualifierEnum#5_prime_utr biolink:NamedThing Graph biolink:LogicalInterpretationEnum#inverse_all_some biolink:NamedThing Graph biolink:PhaseEnum#0 biolink:NamedThing Graph biolink:PhaseEnum#1 biolink:NamedThing Graph biolink:PhaseEnum#2 biolink:NamedThing Graph biolink:ReactionDirectionEnum#bidirectional biolink:NamedThing Graph biolink:ReactionDirectionEnum#left_to_right biolink:NamedThing Graph biolink:ReactionDirectionEnum#neutral biolink:NamedThing Graph biolink:ReactionDirectionEnum#right_to_left biolink:NamedThing Graph biolink:ReactionSideEnum#left biolink:NamedThing Graph biolink:ReactionSideEnum#right biolink:NamedThing Graph biolink:ResourceRoleEnum#aggregator_knowledge_source biolink:NamedThing Graph biolink:ResourceRoleEnum#primary_knowledge_source biolink:NamedThing Graph biolink:ResourceRoleEnum#supporting_data_source biolink:NamedThing Graph biolink:SequenceEnum#aa biolink:NamedThing Graph biolink:SequenceEnum#na biolink:NamedThing Graph biolink:StrandEnum#+ biolink:NamedThing Graph biolink:StrandEnum#- biolink:NamedThing Graph biolink:StrandEnum#. biolink:NamedThing Graph biolink:StrandEnum#? biolink:NamedThing Graph https://www.alliancegenome.org/primaryId biolink:id Graph https://www.alliancegenome.org/symbol biolink:symbol Graph https://www.alliancegenome.org/synonyms biolink:synonym Graph https://www.ama-assn.org/practice-management/cpt/has_add_on_code biolink:related_to Graph https://www.ama-assn.org/practice-management/cpt/has_possibly_included_panel_element biolink:has_attribute Graph https://www.ama-assn.org/practice-management/cpt/mapped_to biolink:related_to Graph https://www.ama-assn.org/practice-management/cpt/panel_element_of biolink:part_of Graph https://www.ama-assn.org/practice-management/cpt/panel_element_of_possibly_included biolink:part_of Graph https://www.dgidb.org/interaction_typesaffects biolink:affects Graph https://www.dgidb.org/interaction_typescofactor biolink:directly_physically_interacts_with Graph https://www.ebi.ac.uk/chembl/mechanism/inspect/disrupting_agent biolink:disrupts Graph https://www.ebi.ac.uk/chembl/mechanism/inspect/equivalent_to biolink:same_as Graph https://www.ebi.ac.uk/chembl/mechanism/inspect/overlaps_with biolink:overlaps Graph https://www.ebi.ac.uk/chembl/mechanism/inspect/subset_of biolink:subclass_of Graph https://www.ebi.ac.uk/chembl/mechanism/inspect/superset_of biolink:superclass_of Graph https://www.nlm.nih.gov/research/umls/sourcereleasedocs/current/VANDF/ingredient_of biolink:part_of Graph https://www.nlm.nih.gov/research/umls/sourcereleasedocs/current/VANDF/inverse_isa biolink:superclass_of Graph https://www.nlm.nih.gov/research/umls/sourcereleasedocs/current/VANDF/isa biolink:subclass_of Graph https://www.wikidata.org/entity/P105 biolink:has_taxonomic_rank Graph https://www.wikidata.org/entity/P2888 biolink:exact_match Graph https://www.wikidata.org/entity/P3433 biolink:is_sequence_variant_of Graph https://www.wikidata.org/entity/Q104053 biolink:PhenotypicFeature Graph https://www.wikidata.org/entity/Q11053 biolink:RNAProduct Graph https://www.wikidata.org/entity/Q12136 biolink:Disease Graph https://www.wikidata.org/entity/Q12140 biolink:Drug Graph https://www.wikidata.org/entity/Q1303415 biolink:Cohort Graph https://www.wikidata.org/entity/Q15304597 biolink:SequenceVariant Graph https://www.wikidata.org/entity/Q16521 biolink:OrganismTaxon Graph https://www.wikidata.org/entity/Q169872 biolink:PhenotypicFeature Graph https://www.wikidata.org/entity/Q181394 biolink:has_nutrient Graph https://www.wikidata.org/entity/Q1980247 biolink:chapter Graph https://www.wikidata.org/entity/Q203221 biolink:SiRNA Graph https://www.wikidata.org/entity/Q22325163 biolink:MacromolecularComplex Graph https://www.wikidata.org/entity/Q2278983 biolink:ProteinFamily Graph https://www.wikidata.org/entity/Q25203551 biolink:PhenotypicFeature Graph https://www.wikidata.org/entity/Q28845870 biolink:BiologicalEntity Graph https://www.wikidata.org/entity/Q2996394 biolink:BiologicalProcess Graph https://www.wikidata.org/entity/Q30892994 biolink:PhysiologicalProcess Graph https://www.wikidata.org/entity/Q310899 biolink:MicroRNA Graph https://www.wikidata.org/entity/Q3140971 biolink:Hospitalization Graph https://www.wikidata.org/entity/Q3238407 biolink:RegulatoryRegion Graph https://www.wikidata.org/entity/Q333291 biolink:summary Graph https://www.wikidata.org/entity/Q35120 biolink:NamedThing Graph https://www.wikidata.org/entity/Q373027 biolink:Exon Graph https://www.wikidata.org/entity/Q39893449 biolink:exact_match Graph https://www.wikidata.org/entity/Q39893967 biolink:narrow_match Graph https://www.wikidata.org/entity/Q39894595 biolink:broad_match Graph https://www.wikidata.org/entity/Q417841 biolink:ProteinFamily Graph https://www.wikidata.org/entity/Q424689 biolink:GeneProductMixin Graph https://www.wikidata.org/entity/Q427626 biolink:TaxonomicRank Graph https://www.wikidata.org/entity/Q43460564 biolink:ChemicalEntity Graph https://www.wikidata.org/entity/Q4915012 biolink:Pathway Graph https://www.wikidata.org/entity/Q4936952 biolink:GrossAnatomicalStructure Graph https://www.wikidata.org/entity/Q5058355 biolink:CellularComponent Graph https://www.wikidata.org/entity/Q66088480 biolink:superclass_of Graph https://www.wikidata.org/entity/Q7020 biolink:Genome Graph https://www.wikidata.org/entity/Q7187 biolink:Gene Graph https://www.wikidata.org/entity/Q7239 biolink:OrganismalEntity Graph https://www.wikidata.org/entity/Q7243183 biolink:Transcript Graph https://www.wikidata.org/entity/Q7868 biolink:Cell Graph https://www.wikidata.org/entity/Q795052 biolink:IndividualOrganism Graph https://www.wikidata.org/entity/Q79529 biolink:ChemicalEntity Graph https://www.wikidata.org/entity/Q8054 biolink:Protein Graph https://www.wikidata.org/entity/Q902638 biolink:is_excipient_of Graph https://www.wikidata.org/prop/P1056 biolink:produces Graph https://www.wikidata.org/prop/P1160 biolink:iso_abbreviation Graph https://www.wikidata.org/prop/P123 biolink:publisher Graph https://www.wikidata.org/prop/P1433 biolink:published_in Graph https://www.wikidata.org/prop/P1542 biolink:causes Graph https://www.wikidata.org/prop/P2175 biolink:treats Graph https://www.wikidata.org/prop/P2176 biolink:treated_by Graph https://www.wikidata.org/prop/P2293 biolink:genetically_associated_with Graph https://www.wikidata.org/prop/P2701 biolink:format Graph https://www.wikidata.org/prop/P274 biolink:has_chemical_formula Graph https://www.wikidata.org/prop/P275 biolink:license Graph https://www.wikidata.org/prop/P276 biolink:location_of Graph https://www.wikidata.org/prop/P279 biolink:subclass_of Graph https://www.wikidata.org/prop/P2888 biolink:same_as Graph https://www.wikidata.org/prop/P304 biolink:pages Graph https://www.wikidata.org/prop/P361 biolink:part_of Graph https://www.wikidata.org/prop/P433 biolink:issue Graph https://www.wikidata.org/prop/P478 biolink:volume Graph https://www.wikidata.org/prop/P50 biolink:author Graph https://www.wikidata.org/prop/P527 biolink:has_part Graph https://www.wikidata.org/prop/P577 biolink:creation_date Graph https://www.wikidata.org/prop/P684 biolink:orthologous_to Graph https://www.wikidata.org/prop/P688 biolink:has_gene_product Graph https://www.wikidata.org/prop/P703 biolink:in_taxon Graph https://www.wikidata.org/prop/P828 biolink:caused_by Graph https://www.wikidata.org/prop/P854 biolink:iri Graph https://www.wikidata.org/prop/P98 biolink:editor Graph https://orcid.org/0000-0001-6996-0040 biolink:NamedThing Austin Meier Graph https://orcid.org/0000-0001-7258-9596 biolink:NamedThing Shawn Zheng Kai Tan Graph https://orcid.org/0000-0001-8910-9851 biolink:NamedThing Lynn Schriml Graph https://orcid.org/0000-0002-2908-3327 biolink:NamedThing Anne Thessen Graph https://orcid.org/0000-0002-4366-3088 biolink:NamedThing Pier Luigi Buttigieg Graph https://orcid.org/0000-0002-6601-2165 biolink:NamedThing Christopher J. Mungall Graph https://orcid.org/0000-0002-7073-9172 biolink:NamedThing David Osumi-Sutherland Graph https://orcid.org/0000-0002-7463-6306 biolink:NamedThing Lauren E. Chan Graph https://orcid.org/0000-0002-8461-9745 biolink:NamedThing Marie-Angélique Laporte Graph https://orcid.org/0000-0002-8688-6599 biolink:NamedThing James P. Balhoff Graph https://orcid.org/0000-0003-1617-8244 biolink:NamedThing Lindsay G Cowell Graph https://orcid.org/0000-0003-1940-6740 biolink:NamedThing Anna Maria Masci Graph https://orcid.org/0000-0003-4423-4370 biolink:NamedThing Charles Tapley Hoyt Graph biolink:directly_physically_interacts_with biolink:NamedThing Graph biolink:drug_regulatory_status_world_wide biolink:NamedThing Graph biolink:treats biolink:NamedThing Graph biolink:has_sequence_location biolink:NamedThing Graph biolink:affects_response_to biolink:NamedThing Graph biolink:decreases_response_to biolink:NamedThing Graph biolink:increases_response_to biolink:NamedThing Graph biolink:affects biolink:NamedThing Graph biolink:contributes_to biolink:NamedThing Graph biolink:negatively_correlated_with biolink:NamedThing Graph biolink:positively_correlated_with biolink:NamedThing Graph biolink:diagnoses biolink:NamedThing Graph biolink:p_value biolink:NamedThing Graph biolink:related_to biolink:NamedThing Graph biolink:superclass_of biolink:NamedThing Graph biolink:subclass_of biolink:NamedThing Graph biolink:has_attribute biolink:NamedThing Graph biolink:part_of biolink:NamedThing Graph biolink:physically_interacts_with biolink:NamedThing Graph biolink:same_as biolink:NamedThing Graph biolink:participates_in biolink:NamedThing Graph biolink:located_in biolink:NamedThing Graph biolink:close_match biolink:NamedThing Graph biolink:has_part biolink:NamedThing Graph biolink:causes biolink:NamedThing Graph biolink:quantifier_qualifier biolink:NamedThing Graph biolink:mechanism_of_action biolink:NamedThing Graph biolink:has_count biolink:NamedThing Graph biolink:has_input biolink:NamedThing Graph biolink:occurs_in biolink:NamedThing Graph biolink:coexists_with biolink:NamedThing Graph biolink:has_attribute_type biolink:NamedThing Graph biolink:has_route biolink:NamedThing Graph biolink:has_participant biolink:NamedThing Graph biolink:synonym biolink:NamedThing Graph biolink:preceded_by biolink:NamedThing Graph biolink:precedes biolink:NamedThing Graph biolink:overlaps biolink:NamedThing Graph biolink:develops_from biolink:NamedThing Graph biolink:biological_role_mixin biolink:NamedThing Graph biolink:has_metabolite biolink:NamedThing Graph biolink:is_metabolite biolink:NamedThing Graph biolink:is_metabolite_of biolink:NamedThing Graph biolink:chemical_role_mixin biolink:NamedThing Graph biolink:chemically_similar_to biolink:NamedThing Graph biolink:derives_from biolink:NamedThing Graph biolink:has_completed biolink:NamedThing Graph biolink:has_increased_amount biolink:NamedThing Graph biolink:has_decreased_amount biolink:NamedThing Graph biolink:has_not_completed biolink:NamedThing Graph biolink:lacks_part biolink:NamedThing Graph biolink:has_stressor biolink:NamedThing Graph biolink:has_receptor biolink:NamedThing Graph biolink:derives_into biolink:NamedThing Graph biolink:location_of biolink:NamedThing Graph biolink:model_of biolink:NamedThing Graph biolink:has_variant_part biolink:NamedThing Graph biolink:related_condition biolink:NamedThing Graph biolink:has_unit biolink:NamedThing Graph biolink:mentions biolink:NamedThing Graph biolink:interacting_molecules_category biolink:NamedThing Graph biolink:disease_has_basis_in biolink:NamedThing Graph biolink:disease_has_location biolink:NamedThing Graph biolink:treated_by biolink:NamedThing Graph biolink:in_linkage_disequilibrium_with biolink:NamedThing Graph biolink:has_side_effect biolink:NamedThing Graph biolink:contraindicated_for biolink:NamedThing Graph biolink:reaction_direction biolink:NamedThing Graph biolink:gene_associated_with_condition biolink:NamedThing Graph biolink:condition_associated_with_gene biolink:NamedThing Graph biolink:has_gene_product biolink:NamedThing Graph biolink:produces biolink:NamedThing Graph biolink:has_output biolink:NamedThing Graph biolink:biomarker_for biolink:NamedThing Graph biolink:expressed_in biolink:NamedThing Graph biolink:capable_of biolink:NamedThing Graph biolink:has_phenotype biolink:NamedThing Graph biolink:has_molecular_consequence biolink:NamedThing Graph biolink:has_biomarker biolink:NamedThing Graph biolink:manifestation_of biolink:NamedThing Graph biolink:correlated_with biolink:NamedThing Graph biolink:caused_by biolink:NamedThing Graph biolink:temporally_related_to biolink:NamedThing Graph biolink:has_plasma_membrane_part biolink:NamedThing Graph biolink:in_taxon biolink:NamedThing Graph biolink:gene_product_of biolink:NamedThing Graph biolink:has_active_ingredient biolink:NamedThing Graph biolink:is_active_ingredient_of biolink:NamedThing Graph biolink:acts_upstream_of biolink:NamedThing Graph biolink:acts_upstream_of_or_within biolink:NamedThing Graph biolink:expresses biolink:NamedThing Graph biolink:colocalizes_with biolink:NamedThing Graph biolink:catalyzes biolink:NamedThing Graph biolink:enables biolink:NamedThing Graph biolink:actively_involved_in biolink:NamedThing Graph biolink:enabled_by biolink:NamedThing Graph biolink:member_of biolink:NamedThing Graph biolink:has_member biolink:NamedThing Graph biolink:is_input_of biolink:NamedThing Graph biolink:is_output_of biolink:NamedThing Graph biolink:active_in biolink:NamedThing Graph biolink:genetically_interacts_with biolink:NamedThing Graph biolink:regulates biolink:NamedThing Graph biolink:composed_primarily_of biolink:NamedThing Graph biolink:transcribed_from biolink:NamedThing Graph biolink:transcribed_to biolink:NamedThing Graph biolink:has_evidence biolink:NamedThing Graph biolink:prevents biolink:NamedThing Graph biolink:opposite_of biolink:NamedThing Graph biolink:produced_by biolink:NamedThing Graph biolink:ameliorates biolink:NamedThing Graph biolink:exacerbates biolink:NamedThing Graph biolink:consumes biolink:NamedThing Graph biolink:disrupts biolink:NamedThing Graph biolink:associated_with biolink:NamedThing Graph biolink:acts_upstream_of_or_within_positive_effect biolink:NamedThing Graph biolink:acts_upstream_of_or_within_negative_effect biolink:NamedThing Graph biolink:acts_upstream_of_positive_effect biolink:NamedThing Graph biolink:acts_upstream_of_negative_effect biolink:NamedThing Graph biolink:similar_to biolink:NamedThing Graph biolink:homologous_to biolink:NamedThing Graph biolink:paralogous_to biolink:NamedThing Graph biolink:orthologous_to biolink:NamedThing Graph biolink:xenologous_to biolink:NamedThing Graph biolink:has_quantitative_value biolink:NamedThing Graph biolink:is_missense_variant_of biolink:NamedThing Graph biolink:is_frameshift_variant_of biolink:NamedThing Graph biolink:is_splice_site_variant_of biolink:NamedThing Graph biolink:is_synonymous_variant_of biolink:NamedThing Graph biolink:chi_squared_statistic biolink:NamedThing Graph biolink:summary biolink:NamedThing Graph biolink:contributor biolink:NamedThing Graph biolink:creation_date biolink:NamedThing Graph biolink:author biolink:NamedThing Graph biolink:format biolink:NamedThing Graph biolink:version_of biolink:NamedThing Graph biolink:license biolink:NamedThing Graph biolink:publisher biolink:NamedThing Graph biolink:rights biolink:NamedThing Graph biolink:created_with biolink:NamedThing Graph biolink:retrieved_on biolink:NamedThing Graph biolink:has_numeric_value biolink:NamedThing Graph biolink:associated_with_sensitivity_to biolink:NamedThing Graph biolink:broad_synonym biolink:NamedThing Graph biolink:exact_synonym biolink:NamedThing Graph biolink:narrow_synonym biolink:NamedThing Graph biolink:related_synonym biolink:NamedThing Graph biolink:latitude biolink:NamedThing Graph biolink:longitude biolink:NamedThing Graph biolink:broad_match biolink:NamedThing Graph biolink:exact_match biolink:NamedThing Graph biolink:narrow_match biolink:NamedThing Graph biolink:distribution_download_url biolink:NamedThing Graph biolink:has_topic biolink:NamedThing Graph biolink:mesh_terms biolink:NamedThing Graph biolink:xref biolink:NamedThing Graph biolink:id biolink:NamedThing Graph biolink:end_coordinate biolink:NamedThing Graph biolink:phase biolink:NamedThing Graph biolink:start_coordinate biolink:NamedThing Graph biolink:genome_build biolink:NamedThing Graph biolink:strand biolink:NamedThing Graph biolink:logical_interpretation biolink:NamedThing Graph biolink:symbol biolink:NamedThing Graph biolink:interacts_with biolink:NamedThing Graph biolink:predisposes biolink:NamedThing Graph biolink:has_taxonomic_rank biolink:NamedThing Graph biolink:is_sequence_variant_of biolink:NamedThing Graph biolink:has_nutrient biolink:NamedThing Graph biolink:chapter biolink:NamedThing Graph biolink:has_excipient biolink:NamedThing Graph biolink:is_excipient_of biolink:NamedThing Graph biolink:iso_abbreviation biolink:NamedThing Graph biolink:published_in biolink:NamedThing Graph biolink:genetically_associated_with biolink:NamedThing Graph biolink:has_chemical_formula biolink:NamedThing Graph biolink:pages biolink:NamedThing Graph biolink:issue biolink:NamedThing Graph biolink:volume biolink:NamedThing Graph biolink:iri biolink:NamedThing Graph biolink:editor biolink:NamedThing Graph faldo:location biolink:has_sequence_location Graph DATA:1669 biolink:p_value Graph DRUGBANK:category biolink:has_attribute Graph DRUGBANK:chelator biolink:directly_physically_interacts_with Graph DRUGBANK:component_of biolink:part_of Graph DRUGBANK:drug-interaction biolink:physically_interacts_with Graph DRUGBANK:external-identifier biolink:same_as Graph DRUGBANK:pathway biolink:participates_in Graph DRUGBANK:treats biolink:treats Graph HMDB:at_cellular_location biolink:located_in Graph HMDB:at_tissue biolink:located_in Graph HMDB:disease biolink:related_to Graph HMDB:has_protein_association biolink:related_to Graph HMDB:in_biospecimen biolink:located_in Graph HMDB:in_pathway biolink:participates_in Graph MEDDRA:classified_as biolink:close_match Graph MEDDRA:has_member biolink:has_part Graph MEDDRA:member_of biolink:part_of Graph UMLS:RB biolink:superclass_of Graph UMLS:RO biolink:related_to Graph UMLS:RQ biolink:related_to Graph UMLS:SY biolink:close_match Graph UMLS:class_code_classified_by biolink:related_to Graph UMLS:component_of biolink:part_of Graph UMLS:exhibited_by biolink:related_to Graph UMLS:has_component biolink:has_part Graph UMLS:has_context_binding biolink:related_to Graph UMLS:has_form biolink:related_to Graph UMLS:has_mapping_qualifier biolink:related_to Graph UMLS:has_owning_affiliate biolink:part_of Graph UMLS:has_physiologic_effect biolink:causes Graph UMLS:has_structural_class biolink:has_attribute Graph UMLS:has_supported_concept_property biolink:has_attribute Graph UMLS:has_supported_concept_relationship biolink:has_attribute Graph UMLS:larger_than biolink:related_to Graph UMLS:mapped_to biolink:related_to Graph UMLS:may_be_qualified_by biolink:has_attribute Graph UMLS:measures biolink:quantifier_qualifier Graph UMLS:owning_section_of biolink:related_to Graph UMLS:owning_subsection_of biolink:part_of Graph UMLS:related_to biolink:related_to Graph HCPCS:mapped_to biolink:related_to Graph NDDF:has_dose_form biolink:subclass_of Graph NDDF:has_ingredient biolink:has_part Graph NDDF:ingredient_of biolink:part_of Graph RXCUI:consists_of biolink:has_part Graph RXCUI:constitutes biolink:part_of Graph RXCUI:has_dose_form biolink:subclass_of Graph RXCUI:has_doseformgroup biolink:subclass_of Graph RXCUI:has_form biolink:related_to Graph RXCUI:has_ingredient biolink:has_part Graph RXCUI:has_part biolink:has_part Graph RXCUI:has_quantified_form biolink:close_match Graph RXCUI:has_tradename biolink:synonym Graph RXCUI:ingredient_of biolink:part_of Graph RXCUI:ingredients_of biolink:part_of Graph RXCUI:inverse_isa biolink:superclass_of Graph RXCUI:isa biolink:subclass_of Graph RXCUI:part_of biolink:part_of Graph RXCUI:precise_ingredient_of biolink:part_of Graph RXCUI:reformulated_to biolink:related_to Graph BFO:0000050 biolink:part_of part_of a core relation that holds between a part and its whole Graph BFO:0000051 biolink:has_part has_part a core relation that holds between a whole and its part Graph BFO:0000054 biolink:related_to realized in Graph BFO:0000055 biolink:has_part realizes Graph BFO:0000056 biolink:participates_in Graph BFO:0000062 biolink:preceded_by preceded by x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. Graph BFO:0000063 biolink:precedes precedes x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. Graph BFO:0000066 biolink:occurs_in occurs in b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t Graph BFO:0000117 biolink:has_part Graph BFO:0000167 biolink:has_participant Graph BSPO:0000096 biolink:coexists_with anterior to Graph BSPO:0000097 biolink:coexists_with distal to Graph BSPO:0000098 biolink:coexists_with dorsal to Graph BSPO:0000099 biolink:coexists_with posterior to Graph BSPO:0000100 biolink:coexists_with proximal to Graph BSPO:0000102 biolink:coexists_with ventral to Graph BSPO:0000104 biolink:coexists_with Graph BSPO:0000107 biolink:located_in deep to Graph BSPO:0000108 biolink:located_in superficial to Graph BSPO:0000110 biolink:coexists_with Graph BSPO:0000113 biolink:coexists_with Graph BSPO:0000120 biolink:located_in in left side of Graph BSPO:0000121 biolink:located_in in right side of Graph BSPO:0000122 biolink:located_in in posterior side of Graph BSPO:0000123 biolink:located_in in anterior side of Graph BSPO:0000124 biolink:located_in Graph BSPO:0000125 biolink:located_in Graph BSPO:0000126 biolink:located_in in lateral side of Graph BSPO:0001100 biolink:located_in Graph BSPO:0001101 biolink:located_in Graph BSPO:0001106 biolink:part_of proximalmost part of Graph BSPO:0001107 biolink:located_in immediately deep to Graph BSPO:0001108 biolink:part_of distalmost part of Graph BSPO:0001113 biolink:part_of Graph BSPO:0001115 biolink:part_of Graph BSPO:0005001 biolink:overlaps Graph BSPO:0015001 biolink:coexists_with Graph BSPO:0015002 biolink:coexists_with Graph BSPO:0015003 biolink:coexists_with Graph BSPO:0015005 biolink:coexists_with Graph BSPO:0015006 biolink:coexists_with Graph BSPO:0015007 biolink:coexists_with Graph BSPO:0015008 biolink:coexists_with Graph BSPO:0015009 biolink:coexists_with Graph BSPO:0015012 biolink:coexists_with Graph BSPO:0015014 biolink:coexists_with Graph BSPO:0015101 biolink:located_in Graph BSPO:0015102 biolink:located_in Graph BSPO:0015202 biolink:located_in Graph BSPO:parallel_to biolink:coexists_with Graph BTO:develops_from biolink:develops_from Graph BTO:related_to biolink:related_to Graph CHEBI:10545 biolink:ChemicalSubstance electron Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV. Graph Elektron|beta|beta(-)|beta-particle|e|e(-)|e-|electron|negatron CHEBI:130181 biolink:biological_role_mixin calmodulin antagonist An antagonist that interferes with the action of the calcium-binding messenger protein calmodulin. Graph CHEBI:131604 biolink:is_metabolite_of Mycoplasma genitalium metabolite Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium. Graph Mycoplasma genitalium metabolites CHEBI:131699 biolink:biological_role_mixin EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor A DNA polymerase inhibitor that interferes with the action of a DNA-directed DNA polymerase (EC 2.7.7.7). Graph DNA duplicase inhibitor|DNA duplicase inhibitors|DNA nucleotidyltransferase (DNA-directed) inhibitor|DNA nucleotidyltransferase (DNA-directed) inhibitors|DNA nucleotidyltransferase inhibitor|DNA nucleotidyltransferase inhibitors|DNA polymerase I inhibitor|DNA polymerase I inhibitors|DNA polymerase II inhibitor|DNA polymerase II inhibitors|DNA polymerase III inhibitor|DNA polymerase III inhibitors|DNA polymerase alpha inhibitor|DNA polymerase alpha inhibitors|DNA polymerase beta inhibitor|DNA polymerase beta inhibitors|DNA polymerase gamma inhibitor|DNA polymerase gamma inhibitors|DNA polymerase inhibitor|DNA polymerase inhibitors|DNA replicase inhibitor|DNA replicase inhibitors|DNA-dependent DNA polymerase inhibitor|DNA-dependent DNA polymerase inhibitors|DNA-directed DNA polymerase (EC 2.7.7.7) inhibitor|DNA-directed DNA polymerase (EC 2.7.7.7) inhibitors|EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitors|EC 2.7.7.7 inhibitor|EC 2.7.7.7 inhibitors|Klenow fragment inhibitor|Klenow fragment inhibitors|Taq DNA polymerase inhibitor|Taq DNA polymerase inhibitors|Taq Pol I inhibitor|Taq Pol I inhibitors|Tca DNA polymerase inhibitor|Tca DNA polymerase inhibitors|deoxynucleate polymerase inhibitor|deoxynucleate polymerase inhibitors|deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) inhibitor|deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) inhibitors|deoxyribonucleate nucleotidyltransferase inhibitor|deoxyribonucleate nucleotidyltransferase inhibitors|deoxyribonucleic acid duplicase inhibitor|deoxyribonucleic acid duplicase inhibitors|deoxyribonucleic acid polymerase inhibitor|deoxyribonucleic acid polymerase inhibitors|deoxyribonucleic duplicase inhibitor|deoxyribonucleic duplicase inhibitors|deoxyribonucleic polymerase I inhibitor|deoxyribonucleic polymerase I inhibitors|deoxyribonucleic polymerase inhibitor|deoxyribonucleic polymerase inhibitors|duplicase inhibitor|duplicase inhibitors|sequenase inhibitor|sequenase inhibitors CHEBI:13193 biolink:chemical_role_mixin hydrogen acceptor A molecular entity that can undergo reduction by the gain of hydrogen atom(s). Graph A CHEBI:136651 biolink:biological_role_mixin S100 calcium-binding protein B inhibitor Any inhibitor of S100 calcium-binding protein B. Graph S100 calcium-binding protein B inhibitors|S100B inhibitor|S100B inhibitors CHEBI:137626 biolink:biological_role_mixin EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 11beta-hydroxysteroid dehydrogenase (EC 1.1.1.146). Graph 11beta-hydroxy steroid dehydrogenase inhibitor|11beta-hydroxy steroid dehydrogenase inhibitors|11beta-hydroxysteroid dehydrogenase inhibitor|11beta-hydroxysteroid dehydrogenase inhibitors|11beta-hydroxysteroid dehydrogenase type 1 inhibitor|11beta-hydroxysteroid dehydrogenase type 1 inhibitors|11beta-hydroxysteroid:NADP(+) 11-oxidoreductase inhibitor|11beta-hydroxysteroid:NADP(+) 11-oxidoreductase inhibitors|EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitors|EC 1.1.1.146 inhibitor|EC 1.1.1.146 inhibitors|beta-hydroxysteroid dehydrogenase inhibitor|beta-hydroxysteroid dehydrogenase inhibitors|corticosteroid 11-reductase inhibitor|corticosteroid 11-reductase inhibitors|corticosteroid 11beta-dehydrogenase inhibitor|corticosteroid 11beta-dehydrogenase inhibitors|dehydrogenase, 11beta-hydroxy steroid inhibitor|dehydrogenase, 11beta-hydroxy steroid inhibitors CHEBI:137684 biolink:is_metabolite_of Papio hamadryas metabolite Any mammalian metabolite produced during a metabolic reaction in Papio hamadryas. Graph P. hamadryas metabolite|P. hamadryas metabolites|Papio hamadryas metabolites CHEBI:138103 biolink:chemical_role_mixin inorganic acid A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water. Graph inorganic acids|mineral acid|mineral acids CHEBI:138208 biolink:biological_role_mixin carotenoid biosynthesis inhibitor Any pathway inhibitor that acts on the carotenoid biosynthesis pathway. Graph carotenogenesis inhibitor|carotenogenesis inhibitors|carotenoid biosynthesis inhibitors|carotenoid-biosynthesis inhibitor|carotenoid-biosynthesis inhibitors CHEBI:138880 biolink:biological_role_mixin autophagy inducer Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell). Graph autophagocytosis inducer|autophagocytosis inducers|autophagy inducers CHEBI:139492 biolink:biological_role_mixin sensitiser A chemical compound that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the compound. Graph sensitisers|sensitizer|sensitizers CHEBI:139512 biolink:biological_role_mixin EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of enoyl-[acyl-carrier-protein] reductase (NADH), EC 1.3.1.9. Graph EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitors|EC 1.3.1.9 inhibitor|EC 1.3.1.9 inhibitors|ENR inhibitor|ENR inhibitors|NADH-enoyl acyl carrier protein reductase inhibitor|NADH-enoyl acyl carrier protein reductase inhibitors|NADH-specific enoyl-ACP reductase inhibitor|NADH-specific enoyl-ACP reductase inhibitors|acyl-[acyl-carrier-protein]:NAD+ oxidoreductase inhibitor|acyl-[acyl-carrier-protein]:NAD+ oxidoreductase inhibitors|enoyl-ACP reductase inhibitor|enoyl-ACP reductase inhibitors|enoyl-[acyl carrier protein] reductase inhibitor|enoyl-[acyl carrier protein] reductase inhibitors CHEBI:140190 biolink:biological_role_mixin calcium-dependent antibiotics Any antimicrobial agent whose activity is dependent on the presence of calcium ions. Graph Ca(2+)-dependent antibiotic|Ca(2+)-dependent antibiotics|Ca-dependent antibiotic|Ca-dependent antibiotics|calcium-dependent antibiotic CHEBI:140602 biolink:is_metabolite_of Arabidopsis thaliana metabolite Any plant metabolite that is produced by Arabidopsis thaliana. Graph Arabidopsis thaliana metabolites CHEBI:140921 biolink:biological_role_mixin Hedgehog signaling pathway inhibitor Any pathway inhibitor that inhibits the Hedgehog signalling pathway. Graph Hedgehog pathway inhibitor|Hedgehog pathway inhibitors|Hedgehog signaling pathway inhibitors CHEBI:140922 biolink:biological_role_mixin glioma-associated oncogene inhibitor An inhibitor of any of the glioma-associated oncogene (GLI) proteins. Graph GLI inhibitor|GLI inhibitors|glioma-associated oncogene inhibitors CHEBI:141153 biolink:biological_role_mixin quinone outside inhibitor A mitochondrial cytochrome-bc1 complex inhibitor that acts at the Quinone 'outer' (Qo) binding site of the cytochrome-bc1 complex. Graph QOI|QOIs|Qo inhibitor|Qo inhibitors|quinone outside inhibitors CHEBI:147285 biolink:biological_role_mixin EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69). Graph 3C-like protease inhibitor|3C-like protease inhibitors|3cLpro inhibitor|3cLpro inhibitors|EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitors|EC 3.4.22.69 inhibitor|EC 3.4.22.69 inhibitors|Mpro inhibitor|Mpro inhibitors|SARS 3C-like protease inhibitor|SARS 3C-like protease inhibitors|SARS coronavirus 3CL protease inhibitor|SARS coronavirus 3CL protease inhibitors|SARS coronavirus main peptidase inhibitor|SARS coronavirus main peptidase inhibitors|SARS coronavirus main protease inhibitor|SARS coronavirus main protease inhibitors|SARS coronavirus main proteinase inhibitor|SARS coronavirus main proteinase inhibitors|SARS-CoV 3CLpro enzyme inhibitor|SARS-CoV 3CLpro enzyme inhibitors|SARS-CoV Mpro inhibitor|SARS-CoV Mpro inhibitors|SARS-CoV main protease inhibitor|SARS-CoV main protease inhibitors|coronavirus 3C-like protease inhibitor|coronavirus 3C-like protease inhibitors|severe acute respiratory syndrome coronavirus main protease inhibitor|severe acute respiratory syndrome coronavirus main protease inhibitors CHEBI:149553 biolink:biological_role_mixin anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. Graph anti-coronaviral agent|anti-coronaviral agents|anti-coronavirus agent|anti-coronavirus agents|anticoronaviral agent|anticoronaviral agents|anticoronaviral drug|anticoronaviral drugs|anticoronavirus agent|anticoronavirus agents|anticoronviral agent|anticoronviral agents CHEBI:15022 biolink:chemical_role_mixin electron donor A molecular entity that can transfer an electron to another molecular entity. Graph Elektronendonator|donneur d'electron|electron donor CHEBI:15339 biolink:chemical_role_mixin acceptor A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity. Graph A|Acceptor|Akzeptor|Hydrogen-acceptor|Oxidized donor|accepteur CHEBI:166831 biolink:chemical_role_mixin copper chelator A chelator that is any compound containing a ligand (typically organic) which is able to form a bond to a central copper atom at two or more points. Graph copper chelate|copper chelating agent|copper chelating agents|copper chelator|copper chelators CHEBI:173084 biolink:biological_role_mixin ferroptosis inhibitor Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms. Graph ferroptosis inhibitors CHEBI:173085 biolink:biological_role_mixin ferroptosis inducer Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms. Graph ferroptosis inducers CHEBI:17499 biolink:chemical_role_mixin hydrogen donor A molecular entity that can undergo oxidation by the loss of hydrogen atom(s). Graph AH2|Donor|Hydrogen-donor|Reduced acceptor CHEBI:17654 biolink:chemical_role_mixin electron acceptor A substance to which an electron may be transferred. Graph Elektronenakzeptor|Oxidized donor|electron acceptor CHEBI:17891 biolink:chemical_role_mixin donor "A molecular entity that can transfer (""donate"") an electron, a pair of electrons, an atom or a group to another molecular entity." Graph Donator|Donor|donneur CHEBI:194338 biolink:biological_role_mixin T-type calcium channel blocker Any agent that interferes with the activity of T-type calcium channels. Graph T-type calcium channel antagonist|T-type calcium channel antagonists|T-type calcium channel blockers CHEBI:20854 biolink:biological_role_mixin ATP synthase inhibitor A mitochondrial respiratory-chain inhibitor that interferes with the action of ATP synthase. Graph CHEBI:21241 biolink:ChemicalSubstance Graph CHEBI:22333 biolink:biological_role_mixin alkylating agent Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases. Graph CHEBI:22586 biolink:chemical_role_mixin antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. Graph antioxidants|antioxydant|antoxidant CHEBI:22587 biolink:biological_role_mixin antiviral agent A substance that destroys or inhibits replication of viruses. Graph anti-viral agent|anti-viral agents|antiviral|antiviral agents|antivirals CHEBI:22676 biolink:biological_role_mixin auxin "Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek alphaupsilonxialphanuomega, ""to grow"")." Graph auxins CHEBI:22695 biolink:chemical_role_mixin base A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base). Graph Base|Base1|Base2|Basen|Nucleobase|base|bases CHEBI:22986 biolink:biological_role_mixin calcium ionophore Graph calcium ionophores CHEBI:23018 biolink:biological_role_mixin EC 4.2.1.1 (carbonic anhydrase) inhibitor An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H(+) ions by the proximal kidney tubule. Graph EC 4.2.1.1 (carbonic anhydrase) inhibitors|EC 4.2.1.1 inhibitor|EC 4.2.1.1 inhibitors|anhydrase inhibitor|anhydrase inhibitors|carbonate anhydrase inhibitor|carbonate anhydrase inhibitors|carbonate dehydratase inhibitor|carbonate dehydratase inhibitors|carbonate hydro-lyase (carbon-dioxide-forming) inhibitor|carbonate hydro-lyase (carbon-dioxide-forming) inhibitors|carbonate hydro-lyase inhibitor|carbonate hydro-lyase inhibitors|carbonic acid anhydrase inhibitor|carbonic acid anhydrase inhibitors|carbonic anhydrase (EC 4.2.1.1) inhibitor|carbonic anhydrase (EC 4.2.1.1) inhibitors|carbonic anhydrase A inhibitor|carbonic anhydrase A inhibitors|carbonic anhydrase inhibitor|carbonic anhydrase inhibitors|carboxyanhydrase inhibitor|carboxyanhydrase inhibitors CHEBI:23240 biolink:chemical_role_mixin chromophore The part (atom or group of atoms) of a molecular entity in which the electronic transition responsible for a given spectral band is approximately localized. Graph chromophore|chromophores CHEBI:23354 biolink:biological_role_mixin coenzyme A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons. Graph coenzyme|coenzymes CHEBI:23357 biolink:biological_role_mixin cofactor An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group). Graph cofactor|cofactors CHEBI:23366 biolink:biological_role_mixin compatible osmolytes Graph CHEBI:23924 biolink:biological_role_mixin enzyme inhibitor A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. Graph enzyme inhibitor|enzyme inhibitors|inhibidor enzimatico|inhibidores enzimaticos|inhibiteur enzymatique|inhibiteurs enzymatiques CHEBI:24020 biolink:biological_role_mixin fat-soluble vitamin (role) Any vitamin that dissolves in fats and are stored in body tissues. Unlike the water-soluble vitamins, they are stored in the body for long periods of time and generally pose a greater risk for toxicity when consumed in excess. Graph fat-soluble vitamin|fat-soluble vitamins|fettloesliche Vitamine CHEBI:24028 biolink:chemical_role_mixin iron(3+) chelator Graph CHEBI:24127 biolink:biological_role_mixin fungicide A substance used to destroy fungal pests. Graph fungicides CHEBI:24319 biolink:biological_role_mixin EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of glutamate--ammonia ligase (EC 6.3.1.2). Graph EC 6.3.1.2 (glutamate--ammonia ligase) inhibitors|EC 6.3.1.2 inhibitor|EC 6.3.1.2 inhibitors|L-glutamate:ammonia ligase (ADP-forming) inhibitor|L-glutamate:ammonia ligase (ADP-forming) inhibitors|L-glutamine synthetase inhibitor|L-glutamine synthetase inhibitors|glutamate--ammonia ligase (EC 6.3.1.2) inhibitor|glutamate--ammonia ligase (EC 6.3.1.2) inhibitors|glutamate--ammonia ligase inhibitor|glutamate--ammonia ligase inhibitors|glutamine synthetase inhibitor|glutamine synthetase inhibitors|glutamylhydroxamic synthetase inhibitor|glutamylhydroxamic synthetase inhibitors CHEBI:24432 biolink:biological_role_mixin biological role A role played by the molecular entity or part thereof within a biological context. Graph biological function CHEBI:24621 biolink:biological_role_mixin hormone Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. Graph endocrine|hormones CHEBI:24853 biolink:biological_role_mixin intercalator A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages. Graph agente intercalante|intercalating agent|intercalating agents|intercalating ligands|intercalators CHEBI:24869 biolink:biological_role_mixin ionophore A compound which can carry specific ions through membranes of cells or organelles. Graph ionophore|ionophores CHEBI:24874 biolink:biological_role_mixin iron ionophore Any ionophore capable of transportation of iron ions across membranes. Graph iron ionophores CHEBI:25212 biolink:is_metabolite_of metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. Graph metabolite|metabolites|primary metabolites|secondary metabolites CHEBI:25355 biolink:biological_role_mixin mitochondrial respiratory-chain inhibitor Graph mitochondrial electron transport chain inhibitors|mitochondrial electron-transport chain inhibitor|mitochondrial respiratory chain inhibitors CHEBI:25435 biolink:biological_role_mixin mutagen An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution. Graph mutagene|mutagenes|mutagenic agent|mutageno|mutagenos|mutagens CHEBI:25442 biolink:is_metabolite_of mycotoxin Poisonous substance produced by fungi. Graph fungal toxins|mycotoxins CHEBI:25512 biolink:biological_role_mixin neurotransmitter An endogenous compound that is used to transmit information across the synapse between a neuron and another cell. Graph neurotransmitters CHEBI:25605 biolink:biological_role_mixin nucleoside antibiotic Graph CHEBI:25728 biolink:biological_role_mixin osmolyte A solute used by a cell under water stress to maintain cell volume. Graph osmolytes CHEBI:26013 biolink:biological_role_mixin pheromone A semiochemical used in olfactory communication between organisms of the same species eliciting a change in sexual or social behaviour. Graph ectohormone|feromone|pheromone|pheromones CHEBI:26087 biolink:biological_role_mixin photosynthetic electron-transport chain inhibitor Graph CHEBI:26089 biolink:biological_role_mixin photosystem-II inhibitor Graph CHEBI:26115 biolink:is_metabolite_of phytoalexin A toxin made by a plant that acts against an organism attacking it. Graph phytoalexins CHEBI:26130 biolink:biological_role_mixin biological pigment An endogenous molecular entity that results in a colour of an organism as the consequence of the selective absorption of light. Graph pigments CHEBI:26155 biolink:biological_role_mixin plant growth regulator A chemical, natural or artificial, that can affect the rate of growth of a plant. Graph plant growth regulators CHEBI:26348 biolink:biological_role_mixin prosthetic group A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity. Graph groupe prosthetique|prosthetic group|prosthetic groups CHEBI:26645 biolink:biological_role_mixin semiochemical A molecular messenger released by an organism that affects the behaviour within or between species. Graph semiochemicals CHEBI:26672 biolink:chemical_role_mixin siderophore Any of low-molecular-mass iron(III)-chelating compounds produced by microorganisms for the purpose of the transport and sequestration of iron. Graph ferrioxamine|ferrioxamines|ironophore|siderochrome|siderochromes|siderophore|siderophores CHEBI:27026 biolink:is_metabolite_of toxin Poisonous substance produced by a biological organism such as a microbe, animal or plant. Graph toxin|toxins CHEBI:27027 biolink:biological_role_mixin micronutrient Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Graph micronutrients|trace elements CHEBI:27311 biolink:is_metabolite_of volatile oil component Any plant metabolite that is found naturally as a component of a volatile oil. Graph essential oil component|essential oil components|ethereal oil component|ethereal oil components|volatile oil components CHEBI:27314 biolink:biological_role_mixin water-soluble vitamin (role) Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine. Graph wasserloesliche Vitamine|water-soluble vitamin|water-soluble vitamins CHEBI:27780 biolink:chemical_role_mixin detergent A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions. Graph Detergents|detergent CHEBI:30212 biolink:ChemicalSubstance photon Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force. Graph Lichtquant|Light|foton|gamma|hnu|light quantum|photon CHEBI:33229 biolink:biological_role_mixin vitamin (role) "A biochemical role played by any micronutrient that is an organic compound. Vitamins are present in foods in small amounts and are essential to normal metabolism and biochemical functions, usually as coenzymes. The term ""vitamines"" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines." Graph vitamin|vitamina|vitaminas|vitamine|vitamines|vitamins|vitaminum CHEBI:33231 biolink:biological_role_mixin antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. Graph antitubercular|antitubercular agents|antitubercular drug|antitubercular drugs|tuberculostatic agent CHEBI:33233 biolink:ChemicalSubstance fundamental particle A particle not known to have substructure. Graph elementary particle|elementary particles CHEBI:33252 biolink:ChemicalSubstance atomic nucleus A nucleus is the positively charged central portion of an atom, excluding the orbital electrons. Graph Atomkern|Kern|noyau|noyau atomique|nuclei|nucleo|nucleo atomico|nucleus|nucleus atomi CHEBI:33253 biolink:ChemicalSubstance nucleon Heavy nuclear particle: proton or neutron. Graph Nukleon|Nukleonen|nucleon|nucleons CHEBI:33280 biolink:biological_role_mixin molecular messenger Graph chemical messenger CHEBI:33281 biolink:biological_role_mixin antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. Graph Antibiotika|Antibiotikum|antibiotic|antibiotics|antibiotique|antimicrobial|antimicrobial agents|antimicrobials|microbicide|microbicides CHEBI:33282 biolink:biological_role_mixin antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. Graph antibacterial agents|antibacterials|bactericide|bactericides CHEBI:33284 biolink:biological_role_mixin nutrient A nutrient is a food component that an organism uses to survive and grow. Graph nutrients CHEBI:33290 biolink:biological_role_mixin food A physiological role played by any substance of either plant, animal or artificial origin which contains essential body nutrients that can be ingested by an organism to provide energy, promote growth, and maintain the processes of life. Graph food material|food materials|food role|foods|foodstuff|foodstuffs CHEBI:33937 biolink:biological_role_mixin macronutrient Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals. Graph macronutrients CHEBI:35195 biolink:chemical_role_mixin surfactant A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces. Graph surface active agent|surfactant|surfactants CHEBI:35219 biolink:biological_role_mixin plant growth retardant Graph plant growth inhibitor|plant growth inhibitors|plant growth retardants CHEBI:35221 biolink:biological_role_mixin antimetabolite A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization. Graph antimetabolite|antimetabolites CHEBI:35222 biolink:biological_role_mixin inhibitor A substance that diminishes the rate of a chemical reaction. Graph inhibidor|inhibiteur|inhibitor|inhibitors CHEBI:35223 biolink:chemical_role_mixin catalyst A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction. Graph Katalysator|catalizador|catalyseur|catalyst CHEBI:35224 biolink:biological_role_mixin effector A small molecule which increases (activator) or decreases (inhibitor) the activity of an (allosteric) enzyme by binding to the enzyme at the regulatory site (which is different from the substrate-binding catalytic site). Graph effector|enzyme modulator CHEBI:35480 biolink:biological_role_mixin analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. Graph CHEBI:35481 biolink:biological_role_mixin non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. Graph CHEBI:35482 biolink:biological_role_mixin opioid analgesic A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. Graph narcotic|narcotic analgesic|narcotic analgesics|narcotics|opioid analgesics CHEBI:35497 biolink:biological_role_mixin androgen antagonist A compound which inhibits or antagonises the biosynthesis or actions of androgens. Graph antiandrogen CHEBI:35522 biolink:biological_role_mixin beta-adrenergic agonist An agent that selectively binds to and activates beta-adrenergic receptors. Graph beta-adrenergic agonists|beta-adrenergic receptor agonist|beta-adrenoceptor agonists CHEBI:35524 biolink:biological_role_mixin sympathomimetic agent A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. Graph sympathomimetic|sympathomimetics CHEBI:35544 biolink:biological_role_mixin EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. Graph (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase inhibitor|(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase inhibitors|(PG)H synthase inhibitor|(PG)H synthase inhibitors|COX inhibitor|EC 1.14.99.1 (cyclooxygenase) inhibitor|EC 1.14.99.1 (cyclooxygenase) inhibitors|EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitors|EC 1.14.99.1 inhibitor|EC 1.14.99.1 inhibitors|PG synthetase inhibitor|PG synthetase inhibitors|cyclooxygenase (EC 1.14.99.1) inhibitor|cyclooxygenase (EC 1.14.99.1) inhibitors|cyclooxygenase inhibitor|cyclooxygenase inhibitors|fatty acid cyclooxygenase inhibitor|fatty acid cyclooxygenase inhibitors|prostaglandin G/H synthase inhibitor|prostaglandin G/H synthase inhibitors|prostaglandin endoperoxide synthetase inhibitor|prostaglandin endoperoxide synthetase inhibitors|prostaglandin synthase inhibitor|prostaglandin synthase inhibitors|prostaglandin synthetase inhibitor|prostaglandin synthetase inhibitors CHEBI:35569 biolink:biological_role_mixin alpha-adrenergic agonist An agent that selectively binds to and activates alpha-adrenergic receptors. Graph alpha-adrenergic agonists|alpha-adrenergic receptor agonist|alpha-adrenoceptor agonists CHEBI:35608 biolink:biological_role_mixin EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor which interferes with the activity of the enzyme protein tyrosine phosphatases (PTPs), EC 3.1.3.48, involved in the removal of phosphate groups from phosphorylated tyrosine residues on proteins. Graph EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitors|EC 3.1.3.48 inhibitor|EC 3.1.3.48 inhibitors|PPT-phosphatase inhibitor|PPT-phosphatase inhibitors|PTP-phosphatase inhibitor|PTP-phosphatase inhibitors|PTPase inhibitor|PTPase inhibitors|[phosphotyrosine]protein phosphatase inhibitor|[phosphotyrosine]protein phosphatase inhibitors|phosphoprotein phosphatase (phosphotyrosine) inhibitor|phosphoprotein phosphatase (phosphotyrosine) inhibitors|phosphotyrosine histone phosphatase inhibitor|phosphotyrosine histone phosphatase inhibitors|phosphotyrosine phosphatase inhibitor|phosphotyrosine phosphatase inhibitors|phosphotyrosine protein phosphatase inhibitor|phosphotyrosine protein phosphatase inhibitors|phosphotyrosylprotein phosphatase inhibitor|phosphotyrosylprotein phosphatase inhibitors|protein phosphotyrosine phosphatase inhibitor|protein phosphotyrosine phosphatase inhibitors|protein tyrosine phosphatase inhibitor|protein tyrosine phosphatase inhibitors|protein-tyrosine-phosphatase (EC 3.1.3.48) inhibitor|protein-tyrosine-phosphatase (EC 3.1.3.48) inhibitors|protein-tyrosine-phosphatase inhibitor|protein-tyrosine-phosphatase inhibitors|protein-tyrosine-phosphate phosphohydrolase inhibitor|protein-tyrosine-phosphate phosphohydrolase inhibitors|tyrosine O-phosphate phosphatase inhibitor|tyrosine O-phosphate phosphatase inhibitors|tyrosylprotein phosphatase inhibitor|tyrosylprotein phosphatase inhibitors CHEBI:35617 biolink:biological_role_mixin flavouring agent A food additive that is used to added improve the taste or odour of a food. Graph flavoring agent|flavoring agents|flavour enhancer|flavour enhancers|flavouring agents CHEBI:35625 biolink:biological_role_mixin EC 3.5.2.6 (beta-lactamase) inhibitor An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of beta-lactamase (EC 3.5.2.6). Graph EC 3.5.2.6 (beta-lactamase) inhibitors|EC 3.5.2.6 inhibitor|EC 3.5.2.6 inhibitors|ampicillinase inhibitor|ampicillinase inhibitors|beta-lactam hydrolase inhibitor|beta-lactam hydrolase inhibitors|beta-lactamase (EC 3.5.2.6) inhibitor|beta-lactamase (EC 3.5.2.6) inhibitors|beta-lactamase A, B, C inhibitor|beta-lactamase A, B, C inhibitors|beta-lactamase AME I inhibitor|beta-lactamase AME I inhibitors|beta-lactamase I-III inhibitor|beta-lactamase I-III inhibitors|beta-lactamase inhibitor|beta-lactamase inhibitors|cephalosporin-beta-lactamase inhibitor|cephalosporin-beta-lactamase inhibitors|cephalosporinase inhibitor|cephalosporinase inhibitors|exopenicillinase inhibitor|exopenicillinase inhibitors|neutrapen inhibitor|neutrapen inhibitors|penicillin amido-beta-lactamhydrolase inhibitor|penicillin amido-beta-lactamhydrolase inhibitors|penicillin beta-lactamase inhibitor|penicillin beta-lactamase inhibitors|penicillinase I, II inhibitor|penicillinase I, II inhibitors|penicillinase inhibitor|penicillinase inhibitors CHEBI:35640 biolink:biological_role_mixin adrenergic uptake inhibitor Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. Graph ARI|NERI|NRI|adrenergic reuptake inhibitor|adrenergic reuptake inhibitors|adrenergic uptake inhibitors|norepinephrine reuptake inhibitor|norepinephrine reuptake inhibitors CHEBI:35664 biolink:biological_role_mixin EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme. Graph HMG-CoA reductase inhibitor|HMG-CoA reductase inhibitors|hydroxymethylglutaryl-CoA reductase inhibitor|hydroxymethylglutaryl-CoA reductase inhibitors CHEBI:35678 biolink:biological_role_mixin histamine agonist A drug that binds to and activates histamine receptors. Although they have been suggested for a variety of clinical applications, histamine agonists have so far been more widely used in research than therapeutically. Graph histamine agonists CHEBI:35703 biolink:biological_role_mixin xenobiotic "A xenobiotic (Greek, xenos ""foreign""; bios ""life"") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means." Graph Xenobiotic|xenobiotic|xenobiotic compounds|xenobiotics CHEBI:35705 biolink:biological_role_mixin immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. Graph immunosuppressant|immunosuppressive agents|inmunosupresor CHEBI:35718 biolink:biological_role_mixin antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. Graph antifungal|antifungal agents|antifungal drug|antifungal drugs|antifungals CHEBI:35816 biolink:biological_role_mixin leprostatic drug A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions. Graph leprostatic|leprostatic agent|leprostatic drugs CHEBI:35818 biolink:biological_role_mixin coccidiostat An agent useful in the treatment or prevention of coccidiosis in man or animals. Graph anticoccidial agent|coccidiostats CHEBI:35820 biolink:biological_role_mixin antiprotozoal drug Any antimicrobial drug which is used to treat or prevent protozoal infections. Graph antiprotozoal agent|antiprotozoal agents|antiprotozoal drugs CHEBI:35856 biolink:biological_role_mixin lipoxygenase inhibitor A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes. Graph lipooxygenase inhibitor|lipoxygenase inhibitors CHEBI:35942 biolink:biological_role_mixin neurotransmitter agent A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. Graph neurotransmitter agents CHEBI:36043 biolink:biological_role_mixin antimicrobial drug A drug used to treat or prevent microbial infections. Graph antimicrobial drugs CHEBI:36044 biolink:biological_role_mixin antiviral drug A substance used in the prophylaxis or therapy of virus diseases. Graph anti-viral drug|anti-virus drug|antiviral drugs CHEBI:36047 biolink:biological_role_mixin antibacterial drug A drug used to treat or prevent bacterial infections. Graph antibacterial drugs CHEBI:36335 biolink:biological_role_mixin trypanocidal drug A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida. Graph antitrypanosomal agent|antitrypanosomal agents|antitrypanosomal drug|antitrypanosomal drugs|trypanocidal drugs|trypanocide|trypanosomicidal agents CHEBI:36338 biolink:ChemicalSubstance lepton Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin). Graph leptons CHEBI:36339 biolink:ChemicalSubstance baryon Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy). Graph baryons CHEBI:36340 biolink:ChemicalSubstance fermion Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi. Graph fermion|fermions CHEBI:36341 biolink:ChemicalSubstance boson Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose. Graph boson|bosons CHEBI:36342 biolink:ChemicalSubstance subatomic particle A particle smaller than an atom. Graph subatomic particles CHEBI:36343 biolink:ChemicalSubstance composite particle A subatomic particle known to have substructure (i.e. consisting of smaller particles). Graph composite particles CHEBI:36344 biolink:ChemicalSubstance hadron Hadron is a subatomic particle which experiences the strong force. Graph hadrons CHEBI:36347 biolink:ChemicalSubstance nuclear particle A nucleus or any of its constituents in any of their energy states. Graph nuclear particle CHEBI:37153 biolink:biological_role_mixin EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor Any EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of phosphoprotein phosphatase (EC 3.1.3.16). Graph 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitor|3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitors|Aspergillus awamori acid protein phosphatase inhibitor|Aspergillus awamori acid protein phosphatase inhibitors|BCKDH phosphatase inhibitor|BCKDH phosphatase inhibitors|EC 3.1.3.16 (protein serine/threonine phosphatase) inhibitors|EC 3.1.3.16 inhibitor|EC 3.1.3.16 inhibitors|HMG-CoA reductase phosphatase inhibitor|HMG-CoA reductase phosphatase inhibitors|branched-chain alpha-keto acid dehydrogenase phosphatase inhibitor|branched-chain alpha-keto acid dehydrogenase phosphatase inhibitors|calcineurin inhibitor|calcineurin inhibitors|casein phosphatase inhibitor|casein phosphatase inhibitors|phosphatase 2A inhibitor|phosphatase 2A inhibitors|phosphatase 2B inhibitor|phosphatase 2B inhibitors|phosphatase C-II inhibitor|phosphatase C-II inhibitors|phosphatase H-II inhibitor|phosphatase H-II inhibitors|phosphatase I inhibitor|phosphatase I inhibitors|phosphatase IB inhibitor|phosphatase IB inhibitors|phosphatase II inhibitor|phosphatase II inhibitors|phosphatase III inhibitor|phosphatase III inhibitors|phosphatase IV inhibitor|phosphatase IV inhibitors|phosphatase SP inhibitor|phosphatase SP inhibitors|phosphoprotein phosphatase (EC 3.1.3.16) inhibitor|phosphoprotein phosphatase (EC 3.1.3.16) inhibitors|phosphoprotein phosphatase inhibitor|phosphoprotein phosphatase inhibitors|phosphoprotein phosphohydrolase inhibitor|phosphoprotein phosphohydrolase inhibitors|phosphopyruvate dehydrogenase phosphatase inhibitor|phosphopyruvate dehydrogenase phosphatase inhibitors|phosphospectrin phosphatase inhibitor|phosphospectrin phosphatase inhibitors|polycation modulated (PCM-) phosphatase inhibitor|polycation modulated (PCM-) phosphatase inhibitors|protein D phosphatase inhibitor|protein D phosphatase inhibitors|protein phosphatase inhibitor|protein phosphatase inhibitors|protein phosphatase-1 inhibitor|protein phosphatase-1 inhibitors|protein phosphatase-2A inhibitor|protein phosphatase-2A inhibitors|protein phosphatase-2B inhibitor|protein phosphatase-2B inhibitors|protein phosphatase-2C inhibitor|protein phosphatase-2C inhibitors|protein serine/threonine phosphatase (EC 3.1.3.16) inhibitors|protein serine/threonine phosphatase inhibitor|protein serine/threonine phosphatase inhibitors|serine/threonine specific protein phosphatase inhibitor|serine/threonine specific protein phosphatase inhibitors CHEBI:37416 biolink:biological_role_mixin EC 2.7.7.6 (RNA polymerase) inhibitor An EC 2.7.7.* (nucleotidyltransferase) inhibitor that interferes with the action of RNA polymerase (EC 2.7.7.6). Graph C RNA formation factors inhibitor|C RNA formation factors inhibitors|C ribonucleic acid formation factors inhibitor|C ribonucleic acid formation factors inhibitors|DNA-dependent RNA nucleotidyltransferase inhibitor|DNA-dependent RNA nucleotidyltransferase inhibitors|DNA-dependent RNA polymerase inhibitor|DNA-dependent RNA polymerase inhibitors|DNA-dependent ribonucleate nucleotidyltransferase inhibitor|DNA-dependent ribonucleate nucleotidyltransferase inhibitors|DNA-directed RNA polymerase inhibitor|DNA-directed RNA polymerase inhibitors|DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitor|DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitors|EC 2.7.7.6 (RNA polymerase) inhibitors|EC 2.7.7.6 inhibitor|EC 2.7.7.6 inhibitors|RNA nucleotidyltransferase (DNA-directed) inhibitor|RNA nucleotidyltransferase (DNA-directed) inhibitors|RNA nucleotidyltransferase inhibitor|RNA nucleotidyltransferase inhibitors|RNA polymerase (EC 2.7.7.6) inhibitor|RNA polymerase (EC 2.7.7.6) inhibitors|RNA polymerase I inhibitor|RNA polymerase I inhibitors|RNA polymerase II inhibitor|RNA polymerase II inhibitors|RNA polymerase III inhibitor|RNA polymerase III inhibitors|RNA polymerase inhibitor|RNA polymerase inhibitors|RNA transcriptase inhibitor|RNA transcriptase inhibitors|deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitor|deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitors|directed RNA polymerase inhibitor|nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitor|nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitors|ribonucleate nucleotidyltransferase inhibitor|ribonucleate nucleotidyltransferase inhibitors|ribonucleate polymerase inhibitor|ribonucleate polymerase inhibitors|ribonucleic acid nucleotidyltransferase inhibitor|ribonucleic acid nucleotidyltransferase inhibitors|ribonucleic acid polymerase inhibitor|ribonucleic acid polymerase inhibitors|ribonucleic acid transcriptase inhibitor|ribonucleic acid transcriptase inhibitors|ribonucleic polymerase inhibitor|ribonucleic polymerase inhibitors|ribonucleic transcriptase inhibitor|ribonucleic transcriptase inhibitors|transcriptase inhibitor|transcriptase inhibitors CHEBI:37527 biolink:chemical_role_mixin acid An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid). Graph Acid|Saeure|Saeuren|acid|acide|acido|acids CHEBI:37670 biolink:biological_role_mixin protease inhibitor A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases). Graph protease inhibitors CHEBI:37699 biolink:biological_role_mixin protein kinase inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases. Graph protein kinase inhibitors CHEBI:37700 biolink:biological_role_mixin EC 2.7.11.13 (protein kinase C) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13). Graph ATP:protein phosphotransferase (diacylglycerol-dependent) inhibitor|ATP:protein phosphotransferase (diacylglycerol-dependent) inhibitors|EC 2.7.11.13 (protein kinase C) inhibitors|EC 2.7.11.13 inhibitor|EC 2.7.11.13 inhibitors|PKC inhibitor|PKC inhibitors|PKCalpha inhibitor|PKCalpha inhibitors|PKCbeta inhibitor|PKCbeta inhibitors|PKCdelta inhibitor|PKCdelta inhibitors|PKCepsilon inhibitor|PKCepsilon inhibitors|PKCgamma inhibitor|PKCgamma inhibitors|PKCzeta inhibitor|PKCzeta inhibitors|PKN3 inhibitor|PKN3 inhibitors|Pkc1p inhibitor|Pkc1p inhibitors|STK24 inhibitor|STK24 inhibitors|cPKC inhibitor|cPKC inhibitors|cPKCalpha inhibitor|cPKCalpha inhibitors|cPKCbeta inhibitor|cPKCbeta inhibitors|cPKCgamma inhibitor|cPKCgamma inhibitors|calcium-dependent protein kinase C inhibitor|calcium-dependent protein kinase C inhibitors|calcium-independent protein kinase C inhibitor|calcium-independent protein kinase C inhibitors|calcium/phospholipid dependent protein kinase inhibitor|calcium/phospholipid dependent protein kinase inhibitors|nPKC inhibitor|nPKC inhibitors|nPKCdelta inhibitor|nPKCdelta inhibitors|nPKCepsilon inhibitor|nPKCepsilon inhibitors|nPKCeta inhibitor|nPKCeta inhibitors|nPKCtheta inhibitor|nPKCtheta inhibitors|protein kinase C (EC 2.7.11.13) inhibitor|protein kinase C (EC 2.7.11.13) inhibitors|protein kinase C inhibitor|protein kinase C inhibitors|protein kinase Cepsilon inhibitor|protein kinase Cepsilon inhibitors CHEBI:37733 biolink:biological_role_mixin EC 3.1.1.8 (cholinesterase) inhibitor An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8). Graph BChE inhibitor|BChE inhibitors|BtChoEase inhibitor|BtChoEase inhibitors|EC 3.1.1.8 (cholinesterase) inhibitors|EC 3.1.1.8 inhibitor|EC 3.1.1.8 inhibitors|anticholineesterase inhibitor|anticholineesterase inhibitors|anticholinesterase|anticholinesterases|benzoylcholinesterase inhibitor|benzoylcholinesterase inhibitors|butyrylcholine esterase inhibitor|butyrylcholine esterase inhibitors|butyrylcholinesterase inhibitor|butyrylcholinesterase inhibitors|choline esterase II (unspecific) inhibitor|choline esterase II (unspecific) inhibitors|choline esterase inhibitor|choline esterase inhibitors|cholinesterase (EC 3.1.1.8) inhibitor|cholinesterase (EC 3.1.1.8) inhibitors|cholinesterase inhibitor|non-specific cholinesterase inhibitor|non-specific cholinesterase inhibitors|propionylcholinesterase inhibitor|propionylcholinesterase inhibitors|pseudocholinesterase inhibitor|pseudocholinesterase inhibitors CHEBI:37845 biolink:biological_role_mixin growth hormone A hormone that specifically regulates growth. Graph GH|Somatotropin|Wachstumshormon|growth hormones CHEBI:37848 biolink:biological_role_mixin plant hormone A plant growth regulator that modulates the formation of stems, leaves and flowers, as well as the development and ripening of fruit. The term includes endogenous and non-endogenous compounds (e.g. active compounds produced by bacteria on the leaf surface) as well as semi-synthetic and fully synthetic compounds. Graph phytohormone|phytohormones|plant growth factor|plant growth factors|plant growth hormone|plant growth hormones|plant hormones CHEBI:37886 biolink:biological_role_mixin adrenergic agonist An agent that selectively binds to and activates adrenergic receptors. Graph adrenergic agonists|adrenergic receptor agonist|adrenoceptor agonists|adrenomimetic|adrenomimetics CHEBI:37887 biolink:biological_role_mixin adrenergic antagonist An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Graph adrenergic antagonists|adrenergic blockaders|adrenergic blocker|adrenergic blockers|adrenergic receptor blockaders|adrenoceptor antagonists CHEBI:37890 biolink:biological_role_mixin alpha-adrenergic antagonist An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. Graph alpha-adrenergic antagonists|alpha-adrenergic blocker|alpha-adrenergic blockers|alpha-adrenergic receptor blockaders|alpha-adrenoceptor antagonists CHEBI:37955 biolink:biological_role_mixin H1-receptor antagonist H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Graph H1 antihistaminics|H1 receptor antagonists|H1 receptor blockaders|H1-receptor antagonists|H1-receptor blocker|H1-receptor blockers|classical antihistamines|classical antihistaminics CHEBI:37956 biolink:biological_role_mixin histamine antagonist Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Graph antihistamine|antihistamines|antihistaminico|antihistaminics|histamine receptor blocker|histamine receptor blockers CHEBI:37957 biolink:biological_role_mixin histaminergic drug Drugs used for their actions on histaminergic systems. Graph histamine agents|histamine drugs|histaminergic agent|histaminergic agents|histaminergic drugs CHEBI:37962 biolink:biological_role_mixin adrenergic agent Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter. Graph adrenergic agents|adrenergic drug|adrenergic drugs|adrenergic neuron agents|adrenergics CHEBI:38068 biolink:biological_role_mixin antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. Graph antimalarials CHEBI:38157 biolink:chemical_role_mixin iron chelator Graph iron chelating agents|iron chelators CHEBI:38161 biolink:chemical_role_mixin chelator A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate. Graph Chelating agent|Metal chelator|chelating agents|chelators|complexon CHEBI:38215 biolink:biological_role_mixin calcium channel blocker One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. Graph calcium channel antagonist|calcium channel antagonists|calcium channel blockers CHEBI:38231 biolink:is_metabolite_of phytotoxin Any toxin produced by a plant. Graph phytotoxins CHEBI:38234 biolink:biological_role_mixin DNA polymerase inhibitor Any inhibitor of a DNA polymerase. Graph CHEBI:38323 biolink:biological_role_mixin cholinergic drug Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons. Graph cholinergic agent|cholinergic drugs|cholinomimetic CHEBI:38324 biolink:biological_role_mixin cholinergic agonist Any drug that binds to and activates cholinergic receptors. Graph acetylcholine agonist|acetylcholine agonists|acetylcholine receptor agonist|cholinergic agonists|cholinomimetic|cholinomimetics CHEBI:38325 biolink:biological_role_mixin muscarinic agonist Any drug that binds to and activates a muscarinic cholinergic receptor. Graph muscarinic acetylcholine receptor agonist|muscarinic agonists|muscarinic cholinergic agonist|muscarinic cholinergic agonists CHEBI:38461 biolink:biological_role_mixin carbamate insecticide Derivatives of carbamic acid with insecticidal properties of general formula ROC(=O)NR(1)R(2), where ROH is an alcohol, oxime, or phenol and R(1) is hydrogen or methyl. Like organophosphate insecticides, they are cholinesterase inhibitors, but carbamate insecticides differ in action from the organophosphates in that the inhibitory effect on cholinesterase is generally brief. Graph carbamate insecticides CHEBI:38462 biolink:biological_role_mixin EC 3.1.1.7 (acetylcholinesterase) inhibitor An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid. Graph AChEI|AcCholE inhibitor|AcCholE inhibitors|EC 3.1.1.7 (acetylcholinesterase) inhibitors|EC 3.1.1.7 inhibitor|EC 3.1.1.7 inhibitors|acetyl.beta-methylcholinesterase inhibitor|acetyl.beta-methylcholinesterase inhibitors|acetylcholine acetylhydrolase inhibitor|acetylcholine acetylhydrolase inhibitors|acetylcholine esterase inhibitor|acetylcholine hydrolase inhibitor|acetylcholine hydrolase inhibitors|acetylcholinesterase (EC 3.1.1.7) inhibitor|acetylcholinesterase (EC 3.1.1.7) inhibitors|acetylcholinesterase inhibitor|acetylcholinesterase inhibitors|acetylthiocholinesterase inhibitor|acetylthiocholinesterase inhibitors|choline esterase I inhibitor|choline esterase I inhibitors|cholinesterase inhibitor|cholinesterase inhibitors|true cholinesterase inhibitor|true cholinesterase inhibitors CHEBI:38496 biolink:biological_role_mixin electron-transport chain inhibitor Graph CHEBI:38497 biolink:biological_role_mixin respiratory-chain inhibitor Graph CHEBI:38498 biolink:biological_role_mixin mitochondrial NADH:ubiquinone reductase inhibitor Graph mitochondrial NADH dehydrogenase inhibitor|mitochondrial complex I inhibitor|mitochondrial complex I inhibitors CHEBI:38499 biolink:biological_role_mixin mitochondrial cytochrome-bc1 complex inhibitor Graph mitochondrial complex III inhibitor|mitochondrial complex III inhibitors CHEBI:38500 biolink:biological_role_mixin EC 1.9.3.1 (cytochrome c oxidase) inhibitor An EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor that interferes with the action of cytochrome c oxidase (EC 1.9.3.1). Graph CcO inhibitor|EC 1.9.3.1 (cytochrome c oxidase) inhibitors|EC 1.9.3.1 inhibitor|EC 1.9.3.1 inhibitors|NADH cytochrome c oxidase inhibitor|NADH cytochrome c oxidase inhibitors|Warburg's respiratory enzyme inhibitor|Warburg's respiratory enzyme inhibitors|complex IV (mitochondrial electron transport) inhibitor|complex IV (mitochondrial electron transport) inhibitors|cytochrome a3 inhibitor|cytochrome a3 inhibitors|cytochrome aa3 inhibitor|cytochrome aa3 inhibitors|cytochrome c oxidase (EC 1.9.3.1) inhibitor|cytochrome c oxidase (EC 1.9.3.1) inhibitors|cytochrome c oxidase inhibitor|cytochrome c oxidase inhibitors|cytochrome oxidase inhibitor|cytochrome oxidase inhibitors|cytochrome-c oxidase inhibitor|cytochrome-c oxidase inhibitors|ferrocytochrome c oxidase inhibitor|ferrocytochrome c oxidase inhibitors|ferrocytochrome-c:oxygen oxidoreductase inhibitor|ferrocytochrome-c:oxygen oxidoreductase inhibitors|indophenol oxidase inhibitor|indophenol oxidase inhibitors|indophenolase inhibitor|indophenolase inhibitors|mitochondrial complex IV inhibitor|mitochondrial complex IV inhibitors|mitochondrial cytochrome-c oxidase inhibitors CHEBI:38502 biolink:biological_role_mixin cytochrome-bc1 complex inhibitor Graph CHEBI:38503 biolink:biological_role_mixin EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor A respiratory-chain inhibitor that interferes with the action of the the enzyme NADH:ubiquinone reductase (H(+)-translocating), EC 1.6.5.3. Graph DPNH-coenzyme Q reductase inhibitor|DPNH-ubiquinone reductase inhibitor|EC 1.6.5.3 (NADH:ubiquinone reductase (H(+)-translocating)) inhibitor|EC 1.6.5.3 (NADH:ubiquinone reductase (H(+)-translocating)) inhibitors|EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitors|EC 1.6.5.3 inhibitor|EC 1.6.5.3 inhibitors|NADH coenzyme Q1 reductase inhibitor|NADH coenzyme Q1 reductase inhibitors|NADH dehydrogenase (ubiquinone) inhibitor|NADH dehydrogenase (ubiquinone) inhibitors|NADH-CoQ oxidoreductase inhibitor|NADH-CoQ oxidoreductase inhibitors|NADH-CoQ reductase inhibitor|NADH-CoQ reductase inhibitors|NADH-Q6 oxidoreductase inhibitor|NADH-coenzyme Q oxidoreductase inhibitors|NADH-coenzyme Q reductase inhibitor|NADH-coenzyme Q reductase inhibitors|NADH-ubiquinone oxidoreductase inhibitor|NADH-ubiquinone oxidoreductase inhibitors|NADH-ubiquinone reductase inhibitor|NADH-ubiquinone reductase inhibitors|NADH-ubiquinone-1 reductase inhibitor|NADH-ubiquinone-1 reductase inhibitors|NADH2 dehydrogenase (ubiquinone) inhibitor|NADH:ubiquinone oxidoreductase complex inhibitor|NADH:ubiquinone oxidoreductase inhibitor|NADH:ubiquinone oxidoreductase inhibitors|NADH:ubiquinone reductase (H(+)-translocating) inhibitor|NADH:ubiquinone reductase (H(+)-translocating) inhibitors|NADH:ubiquinone reductase (H+-translocating) inhibitor|NADH:ubiquinone reductase inhibitor|coenzyme Q reductase|complex 1 dehydrogenase inhibitor|complex I (NADH:Q1 oxidoreductase) inhibitors|complex I (electron transport chain) inhibitors|complex I (mitochondrial electron transport) inhibitors|dihydronicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor|electron transfer complex I inhibitor|electron transfer complex I inhibitors|mitochondrial electron transport complex 1 inhibitor|mitochondrial electron transport complex I inhibitor|mitochondrial electron transport complex I inhibitors|reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor|reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitors|type 1 dehydrogenase inhibitor|type 1 dehydrogenase inhibitors|ubiquinone reductase inhibitor|ubiquinone reductase inhibitors CHEBI:38623 biolink:biological_role_mixin EC 1.4.3.4 (monoamine oxidase) inhibitor An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4). Graph EC 1.4.3.4 (monoamine oxidase) inhibitors|EC 1.4.3.4 inhibitor|EC 1.4.3.4 inhibitors|MAO A inhibitor|MAO A inhibitors|MAO B inhibitor|MAO B inhibitors|MAO inhibitor|MAO inhibitors|MAO-A inhibitor|MAO-A inhibitors|MAO-B inhibitor|MAO-B inhibitors|adrenalin oxidase inhibitor|adrenalin oxidase inhibitors|adrenaline oxidase inhibitor|adrenaline oxidase inhibitors|amine oxidase (flavin-containing) inhibitor|amine oxidase (flavin-containing) inhibitors|amine:oxygen oxidoreductase (deaminating) (flavin-containing) inhibitor|amine:oxygen oxidoreductase (deaminating) (flavin-containing) inhibitors|amine:oxygen oxidoreductase (deaminating) inhibitor|amine:oxygen oxidoreductase (deaminating) inhibitors|epinephrine oxidase inhibitor|epinephrine oxidase inhibitors|monoamine oxidase (EC 1.4.3.4) inhibitor|monoamine oxidase (EC 1.4.3.4) inhibitors|monoamine oxidase A inhibitor|monoamine oxidase A inhibitors|monoamine oxidase B inhibitor|monoamine oxidase B inhibitors|monoamine oxidase inhibitor|monoamine oxidase inhibitors|monoamine:O2 oxidoreductase (deaminating) inhibitor|monoamine:O2 oxidoreductase (deaminating) inhibitors|serotonin deaminase inhibitor|serotonin deaminase inhibitors|tyraminase inhibitor|tyraminase inhibitors|tyramine oxidase inhibitor|tyramine oxidase inhibitors CHEBI:38632 biolink:biological_role_mixin membrane transport modulator Any agent that affects the transport of molecular entities across a biological membrane. Graph membrane transport modulators CHEBI:38633 biolink:biological_role_mixin sodium channel blocker An agent that inhibits sodium influx through cell membranes. Graph Na channel blocker|sodium channel blockers CHEBI:38637 biolink:biological_role_mixin tyrosine kinase inhibitor Any protein kinase inhibitor that interferes with the action of tyrosine kinase. Graph TKI inhibitor|TKI inhibitors|protein tyrosine kinase inhibitor|protein tyrosine kinase inhibitors|tyrosine kinase inhibitors|tyrphostin|tyrphostins CHEBI:38807 biolink:biological_role_mixin calcium channel agonist Agents that increase calcium influx into calcium channels of excitable tissues. Graph calcium channel activator|calcium channel activators|calcium channel agonists CHEBI:38808 biolink:biological_role_mixin calcium channel modulator A membrane transport modulator that is able to regulate intracellular calcium levels. Graph calcium channel modulators CHEBI:38809 biolink:biological_role_mixin ryanodine receptor modulator Graph RyR modulator|ryanodine receptor modulators|ryanodine-sensitive calcium channel modulator|ryanodine-sensitive calcium-release channel modulator CHEBI:39000 biolink:biological_role_mixin sodium channel modulator Graph sodium channel modulators CHEBI:39141 biolink:chemical_role_mixin Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Bronsted base). Graph Bronsted acid|Bronsted-Saeure|acide de Bronsted|donneur d'hydron|hydron donor CHEBI:39142 biolink:chemical_role_mixin Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). Graph Bronsted base|Bronsted-Base|accepteur d'hydron|base de Bronsted|hydron acceptor CHEBI:39144 biolink:chemical_role_mixin Lewis base A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct. Graph Lewis base|Lewis-Base|base de Lewis|donneur d'une paire d'electrons|electron donor CHEBI:39208 biolink:biological_role_mixin antibiotic insecticide Graph CHEBI:39215 biolink:biological_role_mixin antibiotic pesticide Graph CHEBI:39216 biolink:biological_role_mixin antibiotic acaricide Graph CHEBI:39217 biolink:biological_role_mixin antibiotic nematicide Graph CHEBI:39317 biolink:biological_role_mixin growth regulator Any chemical substance that inhibits the life-cycle of an organism. Graph growth regulators CHEBI:46787 biolink:chemical_role_mixin solvent A liquid that can dissolve other substances (solutes) without any change in their chemical composition. Graph Loesungsmittel|solvant|solvents CHEBI:47958 biolink:biological_role_mixin nicotinic acetylcholine receptor agonist An agonist that selectively binds to and activates a nicotinic acetylcholine receptor. Graph muscarinic agonists|nicotinic acetylcholine receptor agonists|nicotinic agonist|nicotinic agonists CHEBI:48001 biolink:biological_role_mixin protein synthesis inhibitor A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein. Graph protein synthesis antagonist|protein synthesis antagonists|protein synthesis inhibitors CHEBI:48219 biolink:biological_role_mixin disinfectant An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity. Graph Desinfektionsmittel|desinfectant|disinfectants|disinfecting agent CHEBI:48278 biolink:biological_role_mixin serotonergic drug Graph serotonergic agents|serotonergic drugs|serotonin drugs CHEBI:48279 biolink:biological_role_mixin serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. Graph 5-HT antagonists|5-hydroxytryptamine antagonists|antiserotonergic agents|serotonin antagonists|serotonin blockaders CHEBI:48353 biolink:biological_role_mixin serine proteinase inhibitor An exogenous or endogenous compound which inhibits serine endopeptidases. Graph serine proteinase inhibitors CHEBI:48354 biolink:chemical_role_mixin polar solvent A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds. Graph polar solvent|polar solvents CHEBI:48355 biolink:chemical_role_mixin non-polar solvent Graph CHEBI:48356 biolink:chemical_role_mixin protic solvent A polar solvent that is capable of acting as a hydron (proton) donor. Graph protogenic solvent CHEBI:48357 biolink:chemical_role_mixin aprotic solvent Graph CHEBI:48358 biolink:chemical_role_mixin polar aprotic solvent A solvent with a comparatively high relative permittivity (or dielectric constant), greater than ca. 15, and a sizable permanent dipole moment, that cannot donate suitably labile hydrogen atoms to form strong hydrogen bonds. Graph dipolar aprotic solvent CHEBI:48359 biolink:chemical_role_mixin protophilic solvent Solvent that is capable of acting as a hydron (proton) acceptor. Graph HBA solvent|hydrogen bond acceptor solvent|protophilic solvent CHEBI:48360 biolink:chemical_role_mixin amphiprotic solvent Self-ionizing solvent possessing both characteristics of Bronsted acids and bases. Graph amphiprotic solvent CHEBI:48539 biolink:biological_role_mixin alpha-adrenergic drug Any drug that acts on an alpha-adrenergic receptor. Graph alpha-adrenergic drugs CHEBI:48540 biolink:biological_role_mixin beta-adrenergic drug Any of the drugs that act on beta-adrenergic receptors. Graph beta-adrenergic drugs CHEBI:48550 biolink:biological_role_mixin EC 1.1.1.21 (aldehyde reductase) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21). Graph ALR2 inhibitor|ALR2 inhibitors|EC 1.1.1.21 (aldehyde reductase) inhibitors|EC 1.1.1.21 inhibitor|EC 1.1.1.21 inhibitors|NADPH-aldopentose reductase inhibitor|NADPH-aldopentose reductase inhibitors|NADPH-aldose reductase inhibitor|NADPH-aldose reductase inhibitors|aldehyde reductase (EC 1.1.1.21) inhibitor|aldehyde reductase (EC 1.1.1.21) inhibitors|aldehyde reductase inhibitor|aldehyde reductase inhibitors|alditol:NAD(P)(+) 1-oxidoreductase inhibitor|alditol:NAD(P)(+) 1-oxidoreductase inhibitors|alditol:NADP oxidoreductase inhibitor|alditol:NADP oxidoreductase inhibitors|alditol:NADP(+) 1-oxidoreductase inhibitor|alditol:NADP(+) 1-oxidoreductase inhibitors|aldose reductase inhibitor|aldose reductase inhibitors|polyol dehydrogenase (NADP(+)) inhibitor|polyol dehydrogenase (NADP(+)) inhibitors CHEBI:48560 biolink:biological_role_mixin dopaminergic agent A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. Graph dopamine agent|dopamine agents|dopamine drug|dopamine drugs|dopaminergic agents CHEBI:48561 biolink:biological_role_mixin dopaminergic antagonist A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists. Graph dopamine antagonist|dopamine blocker|dopamine receptor antagonist|dopaminergic antagonists CHEBI:48578 biolink:chemical_role_mixin radical scavenger A role played by a substance that can react readily with, and thereby eliminate, radicals. Graph free radical scavengers|free-radical scavenger CHEBI:48705 biolink:biological_role_mixin agonist Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own. Graph agonist|agonista|agoniste|agonists CHEBI:48706 biolink:biological_role_mixin antagonist Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. Graph antagonist|antagonista|antagoniste|antagonists CHEBI:48873 biolink:biological_role_mixin cholinergic antagonist Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists. Graph Anticholinergika|Anticholinergikum|acetylcholine antagonists|acetylcholine receptor antagonist|agent anticholinergique|agente anticolinergico|agentes anticolinergicos|anticholinergic agents|anticholinergics|anticholinergiques|anticolinergicos|cholinergic-blocking agents CHEBI:48876 biolink:biological_role_mixin muscarinic antagonist A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists. Graph Antimuskarinika|Antimuskarinikum|agente antimuscarinico|agentes antimuscarinicos|agents antimuscariniques|antimuscarinic agents|antimuscarinicos|muscarinic acetylcholine receptor antagonist|muscarinic antagonists CHEBI:49020 biolink:biological_role_mixin hormone antagonist A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. Graph hormone antagonists CHEBI:49023 biolink:biological_role_mixin prostaglandin antagonist A compound that inhibits the action of prostaglandins. Graph prostaglandin inhibitor CHEBI:49103 biolink:is_metabolite_of drug metabolite Graph drug metabolites CHEBI:49200 biolink:biological_role_mixin EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H(+)/K(+)-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors. Graph (K(+) + H(+))-ATPase inhibitor|(K(+) + H(+))-ATPase inhibitors|ATP phosphohydrolase (H(+)/K(+)-exchanging) inhibitor|ATP phosphohydrolase (H(+)/K(+)-exchanging) inhibitors|EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitors|EC 3.6.3.10 inhibitor|EC 3.6.3.10 inhibitors|H(+)-K(+)-ATPase inhibitor|H(+)-K(+)-ATPase inhibitors|H(+)/K(+)-ATPase inhibitor|H(+)/K(+)-ATPase inhibitors|H(+)/K(+)-exchanging ATPase inhibitor|H(+)/K(+)-exchanging ATPase inhibitors|H,K-ATPase inhibitor|H,K-ATPase inhibitors|proton pump inhibitor|proton pump inhibitors CHEBI:50103 biolink:biological_role_mixin excitatory amino acid agonist An agent that binds to and activates excitatory amino acid receptors. Graph excitatory amino acid agonists|excitatory amino acid receptor agonist|excitatory amino acid receptor agonists CHEBI:50112 biolink:biological_role_mixin sex hormone Any hormone that is responsible for controlling sexual characteristics and reproductive function. Graph Geschlechtshormon|Geschlechtshormone|Sexualhormon|Sexualhormone|hormone sexuelle|hormones sexuelles|sex hormones CHEBI:50113 biolink:biological_role_mixin androgen A sex hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors. Graph Androgen|Androgene|androgene|androgenes|androgeno|androgenos|androgens CHEBI:50114 biolink:biological_role_mixin estrogen A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens. Graph Estrogene|Oestrogen|Oestrogene|estrogene|estrogenes|estrogenes Hormon|estrogeno|estrogenos|estrogens|oestrogen|oestrogene|oestrogenes|oestrogens CHEBI:50183 biolink:biological_role_mixin P450 inhibitor An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. Graph CYP2D6 inhibitor|CYP2D6 inhibitors|P450 inhibitors|cytochrome P450 inhibitor|cytochrome P450 inhibitors CHEBI:50184 biolink:biological_role_mixin ion transport inhibitor A compound which inhibits the movement of an ion across an energy-transducing cell membrane. Graph ion transport inhibitors|ion-transport inhibitor|ion-transport inhibitors CHEBI:50185 biolink:biological_role_mixin fatty acid synthesis inhibitor Any pathway inhibitor that inhibits the synthesis of fatty acids. Graph fatty acid synthesis inhibitors CHEBI:50188 biolink:biological_role_mixin provitamin A substance that can be converted into a vitamin by animal tissues. Graph provitamins CHEBI:50218 biolink:biological_role_mixin EC 3.1.4.* (phosphoric diester hydrolase) inhibitor An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*). Graph EC 3.1.4.* (phosphoric diester hydrolase) inhibitors|phosphodiesterase inhibitor|phosphodiesterase inhibitors|phosphoric diester hydrolase (EC 3.1.4.*) inhibitor|phosphoric diester hydrolase (EC 3.1.4.*) inhibitors|phosphoric diester hydrolase inhibitor|phosphoric diester hydrolase inhibitors CHEBI:50268 biolink:biological_role_mixin GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. Graph GABA modulators CHEBI:50276 biolink:biological_role_mixin EC 5.99.1.2 (DNA topoisomerase) inhibitor A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA. Graph DNA topoisomerase inhibitor|DNA topoisomerase inhibitors|EC 5.99.1.2 (DNA topoisomerase) inhibitors|EC 5.99.1.2 (topoisomerase I) inhibitor|EC 5.99.1.2 (topoisomerase I) inhibitors|EC 5.99.1.2 inhibitor|EC 5.99.1.2 inhibitors|topoisomerase I (EC 5.99.1.2) inhibitor|topoisomerase I (EC 5.99.1.2) inhibitors|topoisomerase I inhibitor|topoisomerase I inhibitors|type I DNA topoisomerase inhibitor|type I DNA topoisomerase inhibitors CHEBI:50390 biolink:biological_role_mixin EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor An EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor that interferes with the action of NAD(P)H dehydrogenase (quinone), EC 1.6.5.2. Graph DT diaphorase inhibitor|EC 1.6.5.2 (NAD(P)H dehydrogenase (quinone)) inhibitor|EC 1.6.5.2 (NAD(P)H dehydrogenase (quinone)) inhibitors|EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitors|EC 1.6.5.2 inhibitor|EC 1.6.5.2 inhibitors|NAD(P)H dehydrogenase (quinone) (EC 1.6.5.2) inhibitor|NAD(P)H dehydrogenase (quinone) (EC 1.6.5.2) inhibitors|NAD(P)H dehydrogenase (quinone) inhibitor|NAD(P)H dehydrogenase (quinone) inhibitors|NAD(P)H dehydrogenase inhibitor|NAD(P)H dehydrogenase inhibitors|NAD(P)H menadione reductase inhibitor|NAD(P)H menadione reductase inhibitors|NAD(P)H-quinone dehydrogenase inhibitor|NAD(P)H-quinone dehydrogenase inhibitors|NAD(P)H-quinone oxidoreductase inhibitor|NAD(P)H-quinone oxidoreductase inhibitors|NAD(P)H2 dehydrogenase (quinone) inhibitor|NAD(P)H2 dehydrogenase (quinone) inhibitors|NAD(P)H: menadione oxidoreductase inhibitor|NAD(P)H: menadione oxidoreductase inhibitors|NAD(P)H:(quinone-acceptor)oxidoreductase inhibitor|NAD(P)H:(quinone-acceptor)oxidoreductase inhibitors|NAD(P)H:quinone oxidoreductase inhibitor|NAD(P)H:quinone oxidoreductase inhibitors|NADH-menadione reductase inhibitor|NADH-menadione reductase inhibitors|NQO1 inhibitor|NQO1 inhibitors|QR1 inhibitor|QR1 inhibitors|dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) inhibitor|dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) inhibitors|diaphorase inhibitor|diaphorase inhibitors|flavoprotein NAD(P)H-quinone reductase inhibitor|flavoprotein NAD(P)H-quinone reductase inhibitors|menadione oxidoreductase inhibitor|menadione oxidoreductase inhibitors|menadione reductase inhibitor|menadione reductase inhibitors|naphthoquinone reductase inhibitor|naphthoquinone reductase inhibitors|p-benzoquinone reductase inhibitor|p-benzoquinone reductase inhibitors|phylloquinone reductase inhibitor|phylloquinone reductase inhibitors|quinone reductase inhibitor|quinone reductase inhibitors|reduced NAD(P)H dehydrogenase inhibitor|reduced NAD(P)H dehydrogenase inhibitors|reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase inhibitor|reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase inhibitors|viologen accepting pyridine nucleotide oxidoreductase inhibitor|viologen accepting pyridine nucleotide oxidoreductase inhibitors|vitamin K reductase inhibitor|vitamin K reductase inhibitors|vitamin-K reductase inhibitor|vitamin-K reductase inhibitors CHEBI:50505 biolink:biological_role_mixin sweetening agent Substance that sweeten food, beverages, medications, etc. Graph sweetener|sweeteners CHEBI:50509 biolink:biological_role_mixin potassium channel blocker An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions. Graph CHEBI:50510 biolink:biological_role_mixin potassium channel modulator Graph CHEBI:50566 biolink:chemical_role_mixin nitric oxide donor An agent, with unique chemical structure and biochemical requirements, which generates nitric oxide. Graph NO donor|NO donors|NO generator|NO generators|NO releasing agent|NO releasing agents|nitric oxide donors|nitric oxide generators|nitric oxide releasing agent|nitric oxide releasing agents CHEBI:50629 biolink:biological_role_mixin cyclooxygenase 2 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2. Graph COX-2 inhibitor|COX-2 inhibitors|PGHS-2 inhibitor|PGHS-2 inhibitors|cyclo-oxygenase 2 inhibitor|cyclo-oxygenase 2 inhibitors|cyclo-oxygenase-2 inhibitor|cyclo-oxygenase-2 inhibitors|cyclooxygenase 2 inhibitors|cyclooxygenase-2 inhibitor|cyclooxygenase-2 inhibitors|prostaglandin H synthase-2 inhibitor|prostaglandin H synthase-2 inhibitors|prostaglandin-endoperoxide synthase 2 inhibitor|prostaglandin-endoperoxide synthase 2 inhibitors CHEBI:50630 biolink:biological_role_mixin cyclooxygenase 1 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1. Graph COX-1 inhibitor|COX-1 inhibitors|PTGS1 inhibitor|PTGS1 inhibitors|cyclo-oxygenase 1 inhibitor|cyclo-oxygenase 1 inhibitors|cyclooxygenase 1 inhibitors|cyclooxygenase-1 inhibitor|cyclooxygenase-1 inhibitors|prostaglandin G/H synthase 1 inhibitor|prostaglandin G/H synthase 1 inhibitors|prostaglandin H2 synthase 1 inhibitor|prostaglandin H2 synthase 1 inhibitors|prostaglandin-endoperoxide synthase 1 inhibitor|prostaglandin-endoperoxide synthase 1 inhibitors CHEBI:50635 biolink:biological_role_mixin EC 3.5.1.5 (urease) inhibitor EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the activity of urease (EC 3.5.1.5), reducing hydrolysis. Graph EC 3.5.1.5 (urease) inhibitors|EC 3.5.1.5 inhibitor|EC 3.5.1.5 inhibitors|urea amidohydrolase inhibitor|urea amidohydrolase inhibitors|urease (EC 3.5.1.5) inhibitor|urease (EC 3.5.1.5) inhibitors|urease inhibitor|urease inhibitors CHEBI:50671 biolink:biological_role_mixin antithyroid drug A drug used to treat hyperthyroidism by reducing the excessive production of thyroid hormones. Graph antithyroid agent|antithyroid agents|antithyroid drugs CHEBI:50683 biolink:biological_role_mixin EC 1.5.1.3 (dihydrofolate reductase) inhibitor An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3). Graph 7,8-dihydrofolate reductase inhibitor|7,8-dihydrofolate reductase inhibitors|DHFR inhibitor|DHFR inhibitors|EC 1.5.1.3 (dihydrofolate reductase) inhibitors|EC 1.5.1.3 inhibitor|EC 1.5.1.3 inhibitors|NADPH-dihydrofolate reductase inhibitor|NADPH-dihydrofolate reductase inhibitors|dihydrofolate reductase (EC 1.5.1.3) inhibitor|dihydrofolate reductase (EC 1.5.1.3) inhibitors|dihydrofolate reductase inhibitor|dihydrofolate reductase inhibitors|dihydrofolic acid reductase inhibitor|dihydrofolic acid reductase inhibitors|dihydrofolic reductase inhibitor|dihydrofolic reductase inhibitors|folic acid reductase inhibitor|folic acid reductase inhibitors|folic reductase inhibitor|folic reductase inhibitors|tetrahydrofolate dehydrogenase inhibitor|tetrahydrofolate dehydrogenase inhibitors CHEBI:50685 biolink:biological_role_mixin antitrichomonal drug A drug used to treat trichomonas infections. Graph antitrichomonal agent CHEBI:50696 biolink:biological_role_mixin EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of peptidoglycan glycosyltransferase (EC 2.4.1.129). Graph EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitors|EC 2.4.1.129 inhibitor|EC 2.4.1.129 inhibitors|PBP3 inhibitor|PG-II inhibitor|PG-II inhibitors|[poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol disaccharidetransferase inhibitor|[poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol disaccharidetransferase inhibitors|bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase inhibitor|bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase inhibitors|penicillin binding protein 1B inhibitor|penicillin binding protein 1B inhibitors|penicillin binding protein 3 inhibitor|penicillin binding protein 3 inhibitors|peptidoglycan glycosyltransferase (EC 2.4.1.129) inhibitor|peptidoglycan glycosyltransferase (EC 2.4.1.129) inhibitors|peptidoglycan glycosyltransferase inhibitor|peptidoglycan glycosyltransferase inhibitors|peptidoglycan transglycosylase inhibitor|peptidoglycan transglycosylase inhibitors|undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase inhibitor|undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase inhibitors CHEBI:50745 biolink:biological_role_mixin progestogen A compound that interacts with progesterone receptors in target tissues to bring about effects similar to those of progesterone. Graph gestagen|gestagens|progestagen|progestagens|progestogens CHEBI:50750 biolink:biological_role_mixin EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Graph DNA gyrase inhibitor|DNA gyrase inhibitors|DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitor|DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitors|DNA topoisomerase (ATP-hydrolysing) inhibitor|DNA topoisomerase (ATP-hydrolysing) inhibitors|DNA topoisomerase II inhibitor|DNA topoisomerase II inhibitors|EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitor|EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitors|EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitors|EC 5.99.1.3 inhibitor|EC 5.99.1.3 inhibitors|inhibitor of type II topoisomerase|inhibitors of type II topoisomerase|topoisomerase II inhibitor|topoisomerase II inhibitors|topoisomerase-II inhibitor|topoisomerase-II inhibitors|type II DNA topoisomerase inhibitor|type II DNA topoisomerase inhibitors CHEBI:50792 biolink:biological_role_mixin estrogen receptor antagonist An antagonist at the estrogen receptor. Graph estrogen receptor antagonists CHEBI:50837 biolink:biological_role_mixin estrogen antagonist A compound which inhibits or antagonises the biosynthesis or actions of estrogens. Graph oestrogen antagonist CHEBI:50846 biolink:biological_role_mixin immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system. Graph Biomodulator|Immune factor|Immunologic factor|Immunological factor|immunomodulators CHEBI:50847 biolink:biological_role_mixin immunological adjuvant A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity. Graph Immunoactivator|Immunoadjuvant|Immunologic adjuvant|Immunopotentiator|Immunostimulant CHEBI:50902 biolink:biological_role_mixin genotoxin A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells. Graph genotoxic agent|genotoxic agents|genotoxins CHEBI:50903 biolink:biological_role_mixin carcinogenic agent A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. Graph agente carcinogeno|cancerigene|cancerogene|carcinogen|carcinogene|carcinogenic agents|carcinogeno|carcinogens CHEBI:50904 biolink:biological_role_mixin allergen A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. Graph alergeno|allergene|allergenic agent CHEBI:50905 biolink:biological_role_mixin teratogenic agent A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect. Graph agent teratogene|teratogen|teratogeno CHEBI:50908 biolink:biological_role_mixin hepatotoxic agent A role played by a chemical compound exihibiting itself through the ability to induce damage to the liver in animals. Graph agente hepatotoxico|hepatotoxic agents|hepatotoxicant|hepatotoxicants|hepatotoxin|hepatotoxins|hepatoxic agent|hepatoxicant CHEBI:50909 biolink:biological_role_mixin nephrotoxic agent A role played by a chemical compound exihibiting itself through the ability to induce damage to the kidney in animals. Graph agente nefrotoxico|nephrotoxicant CHEBI:50910 biolink:biological_role_mixin neurotoxin A poison that interferes with the functions of the nervous system. Graph agente neurotoxico|nerve poison|nerve poisons|neurotoxic agent|neurotoxic agents|neurotoxicant|neurotoxins CHEBI:50914 biolink:biological_role_mixin EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor An inhibitor of phosphatidylinositol 3-kinase, EC 2.7.1.137, a family of related enzymes capable of phosphorylating the 3 position hydroxy group of the inositol ring of a phosphatidylinositol. Graph 1-phosphatidylinositol 3-kinase inhibitor|1-phosphatidylinositol 3-kinase inhibitors|ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase inhibitor|ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase inhibitors|EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitors|EC 2.7.1.137 inhibitor|EC 2.7.1.137 inhibitors|PI(3)K inhibitor|PI(3)K inhibitors|PI-3 kinase inhibitor|PI-3 kinase inhibitors|PI3-kinase inhibitor|PI3-kinase inhibitors|PI3K inhibitor|PI3K inhibitors|PtdIns-3-kinase inhibitor|PtdIns-3-kinase inhibitors|Vps34p inhibitor|Vps34p inhibitors|phosphatidylinositol 3-kinase (EC 2.7.1.137) inhibitor|phosphatidylinositol 3-kinase (EC 2.7.1.137) inhibitors|phosphatidylinositol 3-kinase inhibitor|phosphatidylinositol 3-kinase inhibitors|phosphatidylinositol-3-OH kinase inhibitor|phosphatidylinositol-3-OH kinase inhibitors|phosphoinositide 3-kinase inhibitor|phosphoinositide 3-kinase inhibitors|type I phosphatidylinositol kinase inhibitor|type I phosphatidylinositol kinase inhibitors|type III phosphoinositide 3-kinase inhibitor|type III phosphoinositide 3-kinase inhibitors CHEBI:50916 biolink:biological_role_mixin lipid kinase inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of lipid kinases. Graph lipid kinase inhibitors CHEBI:50925 biolink:biological_role_mixin EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine. Graph A-kinase inhibitor|A-kinase inhibitors|AP50 kinase inhibitor|AP50 kinase inhibitors|ATP-protein transphosphorylase inhibitor|ATP-protein transphosphorylase inhibitors|ATP:protein phosphotransferase (non-specific) inhibitor|ATP:protein phosphotransferase (non-specific) inhibitors|BR serine/threonine-protein kinase 2 inhibitor|BR serine/threonine-protein kinase 2 inhibitors|CK-2 inhibitor|CK-2 inhibitors|CKI inhibitor|CKI inhibitors|CKII inhibitor|CKII inhibitors|EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitors|EC 2.7.11.1 inhibitor|EC 2.7.11.1 inhibitors|HIPK2 inhibitor|HIPK2 inhibitors|Hpr kinase inhibitor|Hpr kinase inhibitors|M phase-specific cdc2 kinase inhibitor|M phase-specific cdc2 kinase inhibitors|MKNK2 inhibitor|MKNK2 inhibitors|PAK-1 inhibitor|PAK-1 inhibitors|PAK1 inhibitor|PAK1 inhibitors|PKA inhibitor|PKA inhibitors|Prp4 protein kinase inhibitor|Prp4 protein kinase inhibitors|Raf kinase inhibitor|Raf kinase inhibitors|Raf-1 inhibitor|Raf-1 inhibitors|STK32 inhibitor|STK32 inhibitors|T-antigen kinase inhibitor|T-antigen kinase inhibitors|WEE1Hu inhibitor|WEE1Hu inhibitors|Wee 1-like kinase inhibitor|Wee 1-like kinase inhibitors|Wee-kinase inhibitor|Wee-kinase inhibitors|betaIIPKC inhibitor|betaIIPKC inhibitors|cAMP-dependent protein kinase A inhibitor|cAMP-dependent protein kinase A inhibitors|cAMP-dependent protein kinase inhibitor|cAMP-dependent protein kinase inhibitors|cGMP-dependent protein kinase inhibitor|cGMP-dependent protein kinase inhibitors|calcium-dependent protein kinase C inhibitor|calcium-dependent protein kinase C inhibitors|calcium/phospholipid-dependent protein kinase inhibitor|calcium/phospholipid-dependent protein kinase inhibitors|casein kinase (phosphorylating) inhibitor|casein kinase (phosphorylating) inhibitors|casein kinase 2 inhibitor|casein kinase 2 inhibitors|casein kinase I inhibitor|casein kinase I inhibitors|casein kinase II inhibitor|casein kinase II inhibitors|casein kinase inhibitor|casein kinase inhibitors|cyclic AMP-dependent protein kinase A inhibitor|cyclic AMP-dependent protein kinase A inhibitors|cyclic AMP-dependent protein kinase inhibitor|cyclic AMP-dependent protein kinase inhibitors|cyclic monophosphate-dependent protein kinase inhibitor|cyclic monophosphate-dependent protein kinase inhibitors|cyclic nucleotide-dependent protein kinase inhibitor|cyclic nucleotide-dependent protein kinase inhibitors|cyclin-dependent kinase inhibitor|cyclin-dependent kinase inhibitors|dsk1 inhibitor|dsk1 inhibitors|epsilon PKC inhibitor|epsilon PKC inhibitors|glycogen synthase a kinase inhibitor|glycogen synthase a kinase inhibitors|glycogen synthase kinase inhibitor|glycogen synthase kinase inhibitors|hydroxyalkyl-protein kinase inhibitor|hydroxyalkyl-protein kinase inhibitors|mitogen-activated S6 kinase inhibitor|mitogen-activated S6 kinase inhibitors|non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitor|non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitors|non-specific serine/threonine protein kinase inhibitor|non-specific serine/threonine protein kinase inhibitors|p21 activated kinase-1 inhibitor|p21 activated kinase-1 inhibitors|p82 kinase inhibitor|p82 kinase inhibitors|phosphorylase b kinase kinase inhibitor|phosphorylase b kinase kinase inhibitors|protein glutamyl kinase inhibitor|protein glutamyl kinase inhibitors|protein kinase (phosphorylating) inhibitor|protein kinase (phosphorylating) inhibitors|protein kinase A inhibitor|protein kinase A inhibitors|protein kinase CK2 inhibitor|protein kinase CK2 inhibitors|protein kinase p58 inhibitor|protein kinase p58 inhibitors|protein phosphokinase inhibitor|protein phosphokinase inhibitors|protein serine kinase inhibitor|protein serine kinase inhibitors|protein serine-threonine kinase inhibitor|protein serine-threonine kinase inhibitors|protein-aspartyl kinase inhibitor|protein-aspartyl kinase inhibitors|protein-cysteine kinase inhibitor|protein-cysteine kinase inhibitors|protein-serine kinase inhibitor|protein-serine kinase inhibitors|protein-serine/threonine kinase inhibitors|ribosomal S6 protein kinase inhibitor|ribosomal S6 protein kinase inhibitors|ribosomal protein S6 kinase II inhibitor|ribosomal protein S6 kinase II inhibitors|serine kinase inhibitor|serine kinase inhibitors|serine protein kinase inhibitor|serine protein kinase inhibitors|serine(threonine) protein kinase inhibitor|serine(threonine) protein kinase inhibitors|serine-specific protein kinase inhibitor|serine-specific protein kinase inhibitors|serine/threonine protein kinase inhibitor|serine/threonine protein kinase inhibitors|threonine-specific protein kinase inhibitor|threonine-specific protein kinase inhibitors|twitchin kinase inhibitor|twitchin kinase inhibitors|type-2 casein kinase inhibitor|type-2 casein kinase inhibitors CHEBI:50949 biolink:biological_role_mixin serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. Graph SSRI|serotonin reuptake inhibitor CHEBI:51039 biolink:biological_role_mixin dopamine uptake inhibitor A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake. Graph DARI|DRI|dopamine reuptake inhibitor|dopamine reuptake inhibitors|dopamine uptake inhibitors CHEBI:51060 biolink:biological_role_mixin hormone agonist A chemical substance which binds to specific hormone receptors activating the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. Graph CHEBI:51086 biolink:chemical_role_mixin chemical role A role played by the molecular entity or part thereof within a chemical context. Graph CHEBI:51373 biolink:biological_role_mixin GABA agonist A drug that binds to and activates gamma-aminobutyric acid receptors. Graph GABA agonists|GABA receptor agonist|GABA receptor agonists|gamma-aminobutyric acid receptor agonist|gamma-aminobutyric acid receptor agonists CHEBI:51374 biolink:biological_role_mixin GABA agent A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems. Graph CHEBI:52206 biolink:biological_role_mixin biochemical role A biological role played by the molecular entity or part thereof within a biochemical context. Graph CHEBI:52208 biolink:biological_role_mixin biophysical role Graph CHEBI:52209 biolink:biological_role_mixin aetiopathogenetic role A role played by the molecular entity or part thereof which causes the development of a pathological process. Graph etiopathogenetic agent|etiopathogenetic role CHEBI:52210 biolink:biological_role_mixin pharmacological role A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties. Graph CHEBI:52211 biolink:biological_role_mixin physiological role Graph CHEBI:52214 biolink:chemical_role_mixin ligand Any molecule or ion capable of binding to a central metal atom to form coordination complexes. Graph ligands CHEBI:52215 biolink:chemical_role_mixin photochemical role A chemical role played by the molecular entity or part thereof in a photochemical process. Graph photochemical roles CHEBI:52290 biolink:biological_role_mixin mitogen A chemical substance that encourages a cell to commence cell division, triggering mitosis. Graph mitogens CHEBI:52424 biolink:biological_role_mixin EC 3.2.1.* (glycosidase) inhibitor An EC 3.2.* (glycosylase) inhibitor that interferes with the action of any glycosidase (i.e. enzymes hydrolysing O- and S-glycosyl compounds, EC 3.2.1.*). Graph EC 3.2.1.* (glycosidase) inhibitors|EC 3.2.1.* inhibitor|EC 3.2.1.* inhibitors|glycosidase (EC 3.2.1.*) inhibitor|glycosidase (EC 3.2.1.*) inhibitors|glycosidase inhibitor|glycosidase inhibitors|glycoside hydrolase inhibitors CHEBI:52425 biolink:biological_role_mixin EC 3.2.1.18 (exo-alpha-sialidase) inhibitor An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein (EC 3.2.1.18), thus preventing the virus from budding from the host cell. Graph EC 3.2.1.18 (exo-alpha-sialidase) inhibitors|EC 3.2.1.18 inhibitor|EC 3.2.1.18 inhibitors|N-acylneuraminate glycohydrolase inhibitor|N-acylneuraminate glycohydrolase inhibitors|acetylneuraminidase inhibitor|acetylneuraminidase inhibitors|acetylneuraminyl hydrolase inhibitor|acetylneuraminyl hydrolase inhibitors|alpha-neuraminidase inhibitor|alpha-neuraminidase inhibitors|exo-alpha-sialidase (EC 3.2.1.18) inhibitor|exo-alpha-sialidase (EC 3.2.1.18) inhibitors|exo-alpha-sialidase inhibitor|exo-alpha-sialidase inhibitors|neuraminidase inhibitor|neuraminidase inhibitors|sialidase inhibitor|sialidase inhibitors CHEBI:53000 biolink:biological_role_mixin epitope The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds. Graph antigenic determinant|epitope function|epitope role CHEBI:53121 biolink:biological_role_mixin adenosine A2A receptor antagonist An antagonist at the A2A receptor. Graph adenosine A2A receptor antagonists CHEBI:53559 biolink:biological_role_mixin topoisomerase IV inhibitor A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Graph topoisomerase IV inhibitors CHEBI:53746 biolink:biological_role_mixin EC 1.1.1.205 (IMP dehydrogenase) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of IMP dehydrogenase (EC 1.1.1.205), so blocking de novo biosynthesis of purine nucleotides. Graph EC 1.1.1.205 (IMP dehydrogenase) inhibitors|EC 1.1.1.205 inhibitor|EC 1.1.1.205 inhibitors|IMP dehydrogenase (EC 1.1.1.205) inhibitor|IMP dehydrogenase (EC 1.1.1.205) inhibitors|IMP dehydrogenase inhibitor|IMP dehydrogenase inhibitors|IMP oxidoreductase inhibitor|IMP oxidoreductase inhibitors|IMP:NAD(+) oxidoreductase inhibitor|IMP:NAD(+) oxidoreductase inhibitors|inosinate dehydrogenase inhibitor|inosinate dehydrogenase inhibitors|inosine 5'-monophosphate dehydrogenase inhibitors|inosine monophosphate dehydrogenase inhibitor|inosine monophosphate dehydrogenase inhibitors|inosine monophosphate oxidoreductase inhibitor|inosine monophosphate oxidoreductase inhibitors|inosinic acid dehydrogenase inhibitor|inosinic acid dehydrogenase inhibitors CHEBI:55322 biolink:biological_role_mixin mu-opioid receptor agonist A compound that exhibits agonist activity at the mu-opioid receptor. Graph mu opioid agonist|mu-opioid agonists|mu-opioid receptor agonists CHEBI:59107 biolink:biological_role_mixin EC 3.4.24.* (metalloendopeptidase) inhibitor Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a metalloendopeptidase (EC 3.4.24.*). Graph EC 3.4.24.* (metalloendopeptidase) inhibitors|EC 3.4.24.* inhibitor|EC 3.4.24.* inhibitors|inhibitor of metalloendopeptidases|inhibitor of metalloendopeptidases (EC 3.4.24.*)|inhibitors of metalloendopeptidases|inhibitors of metalloendopeptidases (EC 3.4.24.*)|metalloendopeptidase (EC 3.4.24.*) inhibitor|metalloendopeptidase (EC 3.4.24.*) inhibitors|metalloendopeptidase inhibitors CHEBI:59132 biolink:biological_role_mixin antigen Any substance that stimulates an immune response in the body, such as through antibody production or by presentation to a T-cell receptor after binding to a major histocompability complex (MHC). Graph antigens CHEBI:59174 biolink:biological_role_mixin hapten Any substance capable of eliciting an immune response only when attached to a large carrier such as a protein. Examples include dinitrophenols; oligosaccharides; peptides; and heavy metals. Graph haptens CHEBI:5924 biolink:biological_role_mixin EC 3.4.21.* (serine endopeptidase) inhibitor Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the activity of a serine endopeptidase (EC 3.4.21.*). Graph EC 3.4.21.* (serine endopeptidase) inhibitors|EC 3.4.21.* inhibitor|EC 3.4.21.* inhibitors|inhibitor of serine endopeptidase (EC 3.4.21.*)|inhibitor of serine endopeptidase (EC 3.4.21.*)s|serine endopeptidase inhibitor|serine endopeptidase inhibitors CHEBI:59285 biolink:biological_role_mixin EC 1.14.13.132 (squalene monooxygenase) inhibitor An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of squalene monooxygenase (EC 1.14.13.132). Graph EC 1.14.13.132 (squalene monooxygenase) inhibitors|squalene 2,3-oxidocyclase inhibitor|squalene 2,3-oxidocyclase inhibitors|squalene epoxidase inhibitor|squalene epoxidase inhibitors|squalene hydroxylase inhibitor|squalene hydroxylase inhibitors|squalene monooxygenase (EC 1.14.13.132) inhibitor|squalene monooxygenase (EC 1.14.13.132) inhibitors|squalene monooxygenase inhibitor|squalene monooxygenase inhibitors|squalene oxydocyclase inhibitor|squalene oxydocyclase inhibitors|squalene-2,3-epoxidase inhibitor|squalene-2,3-epoxidase inhibitors|squalene-2,3-epoxide cyclase inhibitor|squalene-2,3-epoxide cyclase inhibitors CHEBI:59517 biolink:biological_role_mixin DNA synthesis inhibitor Any substance that inhibits the synthesis of DNA. Graph DNA synthesis inhibitors CHEBI:59647 biolink:biological_role_mixin EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of serine palmitoyltransferase (EC 2.3.1.50). Graph 3-oxosphinganine synthetase inhibitor|3-oxosphinganine synthetase inhibitors|EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitors|EC 2.3.1.50 inhibitor|EC 2.3.1.50 inhibitors|SPT inhibitor|SPT inhibitors|acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitor|acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitors|palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitor|palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitors|serine C-palmitoyltransferase (EC 2.3.1.50) inhibitor|serine C-palmitoyltransferase (EC 2.3.1.50) inhibitors|serine C-palmitoyltransferase inhibitor|serine C-palmitoyltransferase inhibitors|serine palmitoyltransferase inhibitor|serine palmitoyltransferase inhibitors CHEBI:59672 biolink:biological_role_mixin EC 2.4.1.16 (chitin synthase) inhibitor A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of chitin synthase (EC 2.4.1.16). Graph EC 2.4.1.16 (chitin synthase) inhibitors|EC 2.4.1.16 inhibitor|EC 2.4.1.16 inhibitors|UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase inhibitor|UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase inhibitors|chitin synthase (EC 2.4.1.16) inhibitor|chitin synthase (EC 2.4.1.16) inhibitors|chitin synthase inhibitor|chitin synthase inhibitors|chitin synthesis inhibitor|chitin synthesis inhibitors|chitin synthetase inhibitor|chitin synthetase inhibitors|chitin-UDP N-acetylglucosaminyltransferase inhibitor|chitin-UDP N-acetylglucosaminyltransferase inhibitors|chitin-UDP acetyl-glucosaminyl transferase inhibitor|chitin-UDP acetyl-glucosaminyl transferase inhibitors|chitin-uridine diphosphate acetylglucosaminyltransferase inhibitor|chitin-uridine diphosphate acetylglucosaminyltransferase inhibitors|trans-N-acetylglucosaminosylase inhibitor|trans-N-acetylglucosaminosylase inhibitors CHEBI:59740 biolink:chemical_role_mixin nucleophilic reagent A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons. Graph nucleophile|nucleophiles|nucleophilic reagents CHEBI:59826 biolink:biological_role_mixin progestin A synthetic progestogen. Graph progestins CHEBI:59897 biolink:biological_role_mixin EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor A DNA polymerase inhibitor that interferes with the activity of reverse transcriptase, EC 2.7.7.49, a viral DNA polymerase enzyme that retroviruses need in order to reproduce. Graph DNA nucleotidyltransferase (RNA-directed) inhibitor|DNA nucleotidyltransferase (RNA-directed) inhibitors|EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitors|EC 2.7.7.49 inhibitor|EC 2.7.7.49 inhibitors|RNA revertase inhibitor|RNA revertase inhibitors|RNA-dependent DNA polymerase inhibitor|RNA-dependent DNA polymerase inhibitors|RNA-dependent deoxyribonucleate nucleotidyltransferase inhibitor|RNA-dependent deoxyribonucleate nucleotidyltransferase inhibitors|RNA-directed DNA polymerase (EC 2.7.7.49) inhibitor|RNA-directed DNA polymerase (EC 2.7.7.49) inhibitors|RNA-directed DNA polymerase inhibitor|RNA-directed DNA polymerase inhibitors|RNA-instructed DNA polymerase inhibitor|RNA-instructed DNA polymerase inhibitors|RT inhibitor|RT inhibitors|deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) inhibitor|deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) inhibitors|reverse transcriptase inhibitor|reverse transcriptase inhibitors|revertase inhibitor|revertase inhibitors|telomerase inhibitor|telomerase inhibitors CHEBI:60258 biolink:biological_role_mixin EC 3.4.* (hydrolases acting on peptide bond) inhibitor A hydrolase inhibitor that interferes with the action of any hydrolase acting on peptide bonds (peptidase), EC 3.4.*.*). Graph EC 3.4.* (hydrolase acting on peptide bond) inhibitor|EC 3.4.* (hydrolase acting on peptide bonds) inhibitors|EC 3.4.* (hydrolases acting on peptide bond) inhibitors|EC 3.4.* (peptidase) inhibitor|EC 3.4.* (peptidase) inhibitors|EC 3.4.* inhibitor|EC 3.4.* inhibitors|inhibitor of hydrolases acting on peptide bond (EC 3.4.*)|inhibitors of hydrolases acting on peptide bond (EC 3.4.*)|peptidase inhibitors|protease inhibitor|protease inhibitors CHEBI:60311 biolink:biological_role_mixin thyroid hormone Any hormone produced by the thyroid gland Graph thyroid hormones CHEBI:60598 biolink:biological_role_mixin opioid agent Any agent that acts on an opioid receptor or affects the life cycle of an opioid transmitter. Graph opioid agents CHEBI:60599 biolink:biological_role_mixin mu-opioid agent Any agent that acts on a mu-opioid receptor. Graph mu-opioid agents CHEBI:60606 biolink:biological_role_mixin opioid receptor agonist An agent that selectively binds to and activates an opioid receptor. Graph opiate agonist|opiate agonists|opioid agonist|opioid agonists|opioid receptor agonists CHEBI:60643 biolink:biological_role_mixin NMDA receptor antagonist Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs. Graph N-methyl-D-aspartate receptor antagonist|N-methyl-D-aspartate receptor antagonists|NMDA receptor antagonists|NMDAR antagonist|NMDAR antagonists CHEBI:60798 biolink:biological_role_mixin excitatory amino acid antagonist Any substance which inhibits the action of receptors for excitatory amino acids. Graph EAA receptor antagonist|EAA receptor antagonists|excitatory amino acid antagonists|excitatory amino acid receptor antagonist|excitatory amino acid receptor antagonists CHEBI:60816 biolink:biological_role_mixin immunogen An antigen capable, on its own, of inducing an immune response. Graph CHEBI:60832 biolink:biological_role_mixin tubulin modulator Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules. Graph tubulin modulators CHEBI:61015 biolink:biological_role_mixin nephrotoxin A poison that interferes with the function of the kidneys. Graph nephrotoxins CHEBI:61016 biolink:biological_role_mixin angiotensin receptor antagonist A hormone antagonist that blocks angiotensin receptors. Graph angiotensin receptor antagonists CHEBI:61115 biolink:biological_role_mixin EC 3.5.1.98 (histone deacetylase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98). Graph EC 3.5.1.98 (histone deacetylase) inhibitors|EC 3.5.1.98 inhibitor|EC 3.5.1.98 inhibitors|HDAC inhibitor|HDAC inhibitors|HDACi|HDACis|HDI|HDIs|histone amidohydrolase inhibitor|histone amidohydrolase inhibitors|histone deacetylase (EC 3.5.1.98) inhibitor|histone deacetylase (EC 3.5.1.98) inhibitors|histone deacetylase inhibitor|histone deacetylase inhibitors CHEBI:61774 biolink:biological_role_mixin inositol phosphorylceramide synthase inhibitor An enzyme inhibitor that inhibits the action of inositol phosphorylceramide synthase. Graph CHEBI:61908 biolink:biological_role_mixin EC 1.14.13.39 (nitric oxide synthase) inhibitor An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of nitric oxide synthase (EC 1.14.13.39). Graph EC 1.14.13.39 (nitric oxide synthase) inhibitors|EC 1.14.13.39 inhibitor|EC 1.14.13.39 inhibitors|NADPH-diaphorase inhibitor|NADPH-diaphorase inhibitors|NO synthase inhibitor|NO synthase inhibitors|endothelium-derived relaxation factor-forming enzyme inhibitor|endothelium-derived relaxation factor-forming enzyme inhibitors|endothelium-derived relaxing factor synthase inhibitor|endothelium-derived relaxing factor synthase inhibitors|nitric oxide synthase (EC 1.14.13.39) inhibitor|nitric oxide synthase (EC 1.14.13.39) inhibitors|nitric oxide synthase inhibitor|nitric oxide synthase inhibitors|nitric oxide synthetase inhibitor|nitric oxide synthetase inhibitors|nitric-oxide synthetase inhibitor|nitric-oxide synthetase inhibitors CHEBI:61950 biolink:biological_role_mixin microtubule-stabilising agent Any substance that interacts with tubulin to promote polymerisation of microtubules. Graph microtubule stabilising agent|microtubule stabilising role|microtubule stabilizing agent|microtubule stabilizing agents|microtubule stabilizing role|microtubule-stabilising agents|microtubule-stabilizing agent CHEBI:61951 biolink:biological_role_mixin microtubule-destabilising agent Any substance that interacts with tubulin to inhibit polymerisation of microtubules. Graph microtubule destabilising agent|microtubule destabilising agents|microtubule destabilising role|microtubule destabilizing role|microtubule-destabilising agents|microtubule-destabilizing agent|microtubule-destabilizing agents CHEBI:62049 biolink:chemical_role_mixin acyl donor Any donor that can transfer acyl groups between molecular entities. Graph CHEBI:62089 biolink:biological_role_mixin EC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any glutamate synthase. Graph EC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitors|EC 1.4.7.1 inhibitor|EC 1.4.7.1 inhibitors|L-glutamate:ferredoxin oxidoreductase (transaminating) inhibitor|L-glutamate:ferredoxin oxidoreductase (transaminating) inhibitors|ferredoxin-dependent glutamate synthase inhibitor|ferredoxin-dependent glutamate synthase inhibitors|ferredoxin-glutamate synthase inhibitor|ferredoxin-glutamate synthase inhibitors|glutamate synthase (ferredoxin) (EC 1.4.7.1) inhibitor|glutamate synthase (ferredoxin) (EC 1.4.7.1) inhibitors|glutamate synthase (ferredoxin) inhibitor|glutamate synthase (ferredoxin) inhibitors|glutamate synthase (ferredoxin-dependent) inhibitor|glutamate synthase (ferredoxin-dependent) inhibitors|glutamate synthase inhibitor|glutamate synthase inhibitors CHEBI:62215 biolink:is_metabolite_of allelochemical A class of secondary metabolites developed by many plants to influence the behaviour, growth or survival of herbivores, and thus acting as a defence against herbivory. Graph allelochemicals CHEBI:62434 biolink:biological_role_mixin EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that interferes with the action of receptor protein-tyrosine kinase (EC 2.7.10.1). Graph AATK inhibitor|AATYK inhibitor|AATYK2 inhibitor|AATYK3 inhibitor|ACH inhibitor|ALK inhibitor|ALK inhibitors|ARK inhibitor|ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type) inhibitor|ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type) inhibitors|AXL inhibitor|BRT inhibitor|Bek inhibitor|Bfgfr inhibitor|Bsk inhibitor|C-FMS inhibitor|CAK inhibitor|CCK4 inhibitor|CD115 inhibitor|CD135 inhibitor|CDw135 inhibitor|CFD1 inhibitor|CKIT inhibitor|CSF1R inhibitor|Cek1 inhibitor|Cek10 inhibitor|Cek11 inhibitor|Cek2 inhibitor|Cek3 inhibitor|Cek5 inhibitor|Cek6 inhibitor|Cek7 inhibitor|DAlk inhibitor|DDR1 inhibitor|DDR2 inhibitor|DKFZp434C1418 inhibitor|DRT inhibitor|DTK inhibitor|Dek inhibitor|Drosophila Eph kinase inhibitor|EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitors|EC 2.7.10.1 inhibitor|EC 2.7.10.1 inhibitors|ECK inhibitor|EDDR1 inhibitor|EGFR inhibitor|EPH inhibitor|EPHA1 inhibitor|EPHA2 inhibitor|EPHA6 inhibitor|EPHA7 inhibitor|EPHA8 inhibitor|EPHB1 inhibitor|EPHB2 inhibitor|EPHB3 inhibitor|EPHB4 inhibitor|EPHT inhibitor|EPHT2 inhibitor|EPHT3 inhibitor|EPHX inhibitor|ERBB inhibitor|ERBB1 inhibitor|ERBB2 inhibitor|ERBB3 inhibitor|ERBB4 inhibitor|ERK inhibitor|Ebk inhibitor|Eek inhibitor|Ehk2 inhibitor|Ehk3 inhibitor|Elk inhibitor|EphB5 inhibitor|Eyk inhibitor|FGFR1 inhibitor|FGFR2 inhibitor|FGFR3 inhibitor|FGFR4 inhibitor|FLG inhibitor|FLK1 inhibitor|FLK2 inhibitor|FLT1 inhibitor|FLT2 inhibitor|FLT3 inhibitor|FLT4 inhibitor|FMS inhibitor|Fv2 inhibitor|HBGFR inhibitor|HEK11 inhibitor|HEK2 inhibitor|HEK3 inhibitor|HEK5 inhibitor|HEK6 inhibitor|HEP inhibitor|HER2 inhibitor|HER3 inhibitor|HER4 inhibitor|HGFR inhibitor|HSCR1 inhibitor|HTK inhibitor|IGF1R inhibitor|INSR inhibitor|INSRR inhibitor|IR inhibitor|IRR inhibitor|JTK12 inhibitor|JTK13 inhibitor|JTK14 inhibitor|JWS inhibitor|K-SAM inhibitor|KDR inhibitor|KGFR inhibitor|KIA0641 inhibitor|KIAA1079 inhibitor|KIAA1459 inhibitor|KIT inhibitor|KLG inhibitor|Kil inhibitor|Kin15 inhibitor|Kin16 inhibitor|LTK inhibitor|MCF3 inhibitor|MEN2A/B inhibitor|MER inhibitor|MERTK inhibitor|MEhk1 inhibitor|MST1R inhibitor|MTC1 inhibitor|MUSK inhibitor|Mdk1 inhibitor|Mdk2 inhibitor|Mdk5 inhibitor|Mep inhibitor|Mlk1 inhibitor|Mlk2 inhibitor|Mrk inhibitor|Myk1 inhibitor|N-SAM inhibitor|NEP inhibitor|NET inhibitor|NGL inhibitor|NOK inhibitor|NTRK1 inhibitor|NTRK2 inhibitor|NTRK3 inhibitor|NTRK4 inhibitor|NTRKR1 inhibitor|NTRKR2 inhibitor|NTRKR3 inhibitor|NYK inhibitor|Neu inhibitor|Nsk2 inhibitor|Nuk inhibitor|PCL inhibitor|PDGFR inhibitor|PDGFRA inhibitor|PDGFRB inhibitor|PHB6 inhibitor|PTK inhibitor|PTK3 inhibitor|PTK7 inhibitor|RET inhibitor|RON inhibitor|ROR1 inhibitor|ROR2 inhibitor|ROS1 inhibitor|RSE inhibitor|RTK inhibitor|RYK inhibitor|SEA inhibitor|SKY inhibitor|STK inhibitor|STK1 inhibitor|Sek2 inhibitor|Sek3 inhibitor|Sek4 inhibitor|Sfr inhibitor|TEK inhibitor|TIE inhibitor|TIE1 inhibitor|TIE2 inhibitor|TIF inhibitor|TKT inhibitor|TRK inhibitor|TRKA inhibitor|TRKB inhibitor|TRKC inhibitor|TRKE inhibitor|TYK1 inhibitor|TYRO10 inhibitor|TYRO3 inhibitor|TYRO7 inhibitor|Tyro11 inhibitor|Tyro5 inhibitor|Tyro6 inhibitor|UFO inhibitor|VEGFR1 inhibitor|VEGFR2 inhibitor|VEGFR3 inhibitor|Vik inhibitor|YK1 inhibitor|Yrk inhibitor|anaplastic lymphoma kinase inhibitor|anaplastic lymphoma kinase inhibitors|ephrin-B3 receptor tyrosine kinase inhibitor|insulin receptor protein-tyrosine kinase inhibitor|neurite outgrowth regulating kinase inhibitor|nork inhibitor|novel oncogene with kinase-domain inhibitor|receptor protein tyrosine kinase inhibitor|receptor protein-tyrosine kinase (EC 2.7.10.1) inhibitor|receptor protein-tyrosine kinase (EC 2.7.10.1) inhibitors|receptor protein-tyrosine kinase inhibitor|receptor protein-tyrosine kinase inhibitors CHEBI:62488 biolink:biological_role_mixin signalling molecule A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell. Graph signal molecule|signal molecules|signaling molecule|signaling molecules|signalling molecules CHEBI:62803 biolink:chemical_role_mixin fuel additive Any additive that enhances the efficiency of fuel. Graph fuel additives|fuel enhancer CHEBI:62872 biolink:biological_role_mixin EC 1.2.3.1 (aldehyde oxidase) inhibitor An EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor which interferes with the action of aldehyde oxidase (EC 1.2.3.1). Graph EC 1.2.3.1 (aldehyde oxidase) inhibitors|EC 1.2.3.1 inhibitor|EC 1.2.3.1 inhibitors|aldehyde oxidase (EC 1.2.3.1) inhibitor|aldehyde oxidase (EC 1.2.3.1) inhibitors|aldehyde oxidase inhibitor|aldehyde oxidase inhibitors|aldehyde:oxygen oxidoreductase inhibitor|aldehyde:oxygen oxidoreductase inhibitors|quinoline oxidase inhibitor|quinoline oxidase inhibitors|retinal oxidase inhibitor|retinal oxidase inhibitors|retinoic acid synthase inhibitor|retinoic acid synthase inhibitors CHEBI:62913 biolink:biological_role_mixin EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of a NAD(+) ADP-ribosyltransferase (EC 2.4.2.30). Graph ADP-ribosyltransferase (polymerising) inhibitor|ADP-ribosyltransferase (polymerising) inhibitors|ADP-ribosyltransferase (polymerizing) inhibitor|ADP-ribosyltransferase (polymerizing) inhibitors|EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitors|EC 2.4.2.30 inhibitor|EC 2.4.2.30 inhibitors|NAD(+) ADP-ribosyltransferase (EC 2.4.2.30) inhibitor|NAD(+) ADP-ribosyltransferase (EC 2.4.2.30) inhibitors|NAD(+) ADP-ribosyltransferase inhibitor|NAD(+) ADP-ribosyltransferase inhibitors|NAD(+):poly(ADP-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitor|NAD(+):poly(ADP-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitors|NAD(+):poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitor|NAD(+):poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitors|PARP|PARPs|poly(ADP-ribose) polymerase inhibitor|poly(ADP-ribose) polymerase inhibitors|poly(ADP-ribose) synthase inhibitor|poly(ADP-ribose) synthase inhibitors|poly(ADP-ribose) synthetase inhibitor|poly(ADP-ribose) synthetase inhibitors|poly(adenosine diphosphate ribose) polymerase inhibitor|poly(adenosine diphosphate ribose) polymerase inhibitors CHEBI:63046 biolink:chemical_role_mixin emulsifier The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability. Graph emulgent|emulgents|emulsifiers CHEBI:63114 biolink:biological_role_mixin sphingosine-1-phosphate receptor agonist An agonist that binds to and activates sphingosine 1-phosphate receptors. Graph EDG receptor agonist|S1P receptor agonist|S1P receptor agonists|SIP agonist|SIP agonists|sphingosine 1-phosphate receptor agonist|sphingosine 1-phosphate receptor agonists|sphingosine-1-phosphate receptor agonists CHEBI:63156 biolink:biological_role_mixin EC 1.1.3.13 (alcohol oxidase) inhibitor An EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor that interferes with the action of alcohol oxidase (EC 1.1.3.13). Graph EC 1.1.3.13 (alcohol oxidase) inhibitors|EC 1.1.3.13 inhibitor|EC 1.1.3.13 inhibitors|alcohol oxidase (EC 1.1.3.13) inhibitor|alcohol oxidase (EC 1.1.3.13) inhibitors|alcohol oxidase inhibitor|alcohol oxidase inhibitors|alcohol:oxygen oxidoreductase inhibitor|alcohol:oxygen oxidoreductase inhibitors|ethanol oxidase inhibitor|ethanol oxidase inhibitors CHEBI:63157 biolink:biological_role_mixin EC 4.2.1.22 (cystathionine beta-synthase) inhibitor An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of cystathionine beta-synthase (EC 4.2.1.22). Graph EC 4.2.1.22 (cystathionine beta-synthase) inhibitors|EC 4.2.1.22 inhibitor|EC 4.2.1.22 inhibitors|L-serine hydro-lyase (adding homocysteine) inhibitor|L-serine hydro-lyase (adding homocysteine) inhibitors|L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming) inhibitor|L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming) inhibitors|beta-thionase inhibitor|beta-thionase inhibitors|cystathionine beta-synthase (EC 4.2.1.22) inhibitor|cystathionine beta-synthase (EC 4.2.1.22) inhibitors|cystathionine beta-synthase inhibitor|cystathionine beta-synthase inhibitors|cystathionine-beta-synthase inhibitor|cystathionine-beta-synthase inhibitors|cysteine synthase inhibitor|cysteine synthase inhibitors|methylcysteine synthase inhibitor|methylcysteine synthase inhibitors|serine sulfhydrase inhibitor|serine sulfhydrase inhibitors|serine sulfhydrylase inhibitor|serine sulfhydrylase inhibitors CHEBI:63158 biolink:biological_role_mixin EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of mitochondrial carnitine O-palmitoyltransferase (EC 2.3.1.21). Graph CPT I (outer membrane carnitine palmitoyl transferase) inhibitor|CPT I (outer membrane carnitine palmitoyl transferase) inhibitors|CPT inhibitor|CPT inhibitors|CPT-A inhibitor|CPT-A inhibitors|CPT-B inhibitor|CPT-B inhibitors|CPTi inhibitor|CPTi inhibitors|CPTo inhibitor|CPTo inhibitors|CTP-1 inhibitor|CTP-1 inhibitors|EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitors|EC 2.3.1.21 inhibitor|EC 2.3.1.21 inhibitors|L-carnitine palmitoyltransferase inhibitor|L-carnitine palmitoyltransferase inhibitors|acylcarnitine transferase inhibitor|acylcarnitine transferase inhibitors|carnitine O-palmitoyltransferase (EC 2.3.1.21) inhibitor|carnitine O-palmitoyltransferase (EC 2.3.1.21) inhibitors|carnitine O-palmitoyltransferase inhibitor|carnitine O-palmitoyltransferase inhibitors|carnitine palmitoyltransferase II inhibitor|carnitine palmitoyltransferase II inhibitors|carnitine palmitoyltransferase inhibitor|carnitine palmitoyltransferase inhibitors|carnitine palmitoyltransferase-1 inhibitor|carnitine palmitoyltransferase-1 inhibitors|carnitine palmitoyltransferase-A inhibitor|carnitine palmitoyltransferase-A inhibitors|mitochondrial carnitine palmitoyltransferase-1 inhibitor|mitochondrial carnitine palmitoyltransferase-1 inhibitors|outer malonyl-CoA inhibitable carnitine palmitoyltransferase inhibitor|outer malonyl-CoA inhibitable carnitine palmitoyltransferase inhibitors|palmitoyl-CoA:L-carnitine O-palmitoyltransferase inhibitor|palmitoyl-CoA:L-carnitine O-palmitoyltransferase inhibitors|palmitoylcarnitine transferase inhibitor|palmitoylcarnitine transferase inhibitors CHEBI:63173 biolink:biological_role_mixin T-cell proliferation inhibitor An inhibitor that interferes with the process of T-cell proliferation. Graph T-cell proliferation inhibitors CHEBI:63247 biolink:chemical_role_mixin reducing agent The element or compound in a reduction-oxidation (redox) reaction that donates an electron to another species. Graph reducer|reducers|reducing agents|reductant|reductants CHEBI:63248 biolink:chemical_role_mixin oxidising agent A substance that removes electrons from another reactant in a redox reaction. Graph oxidant|oxidants|oxidiser|oxidisers|oxidising agents|oxidizer|oxidizers|oxidizing agent|oxidizing agents CHEBI:63332 biolink:biological_role_mixin EC 3.1.3.1 (alkaline phosphatase) inhibitor An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of alkaline phosphatase (EC 3.1.3.1). Graph EC 3.1.3.1 (alkaline phosphatase) inhibitors|EC 3.1.3.1 inhibitor|EC 3.1.3.1 inhibitors|alkaline phenyl phosphatase inhibitor|alkaline phenyl phosphatase inhibitors|alkaline phosphatase (EC 3.1.3.1) inhibitor|alkaline phosphatase (EC 3.1.3.1) inhibitors|alkaline phosphatase inhibitor|alkaline phosphatase inhibitors|alkaline phosphohydrolase inhibitor|alkaline phosphohydrolase inhibitors|alkaline phosphomonoesterase inhibitor|alkaline phosphomonoesterase inhibitors|glycerophosphatase inhibitor|glycerophosphatase inhibitors|orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitor|orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitors|phosphate-monoester phosphohydrolase (alkaline optimum) inhibitor|phosphate-monoester phosphohydrolase (alkaline optimum) inhibitors|phosphomonoesterase inhibitor|phosphomonoesterase inhibitors CHEBI:63490 biolink:chemical_role_mixin explosive A substance capable of undergoing rapid and highly exothermic decomposition. Graph explosive compound|explosive compounds|explosive material|explosives|explosives chemical|explosives chemicals CHEBI:63510 biolink:biological_role_mixin EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of Na(+)/K(+)-transporting ATPase (EC 3.6.3.9). Graph EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitors|EC 3.6.3.9 inhibitor|EC 3.6.3.9 inhibitors|Na(+)/K(+)-ATPase inhibitor|Na(+)/K(+)-ATPase inhibitors|Na(+)/K(+)-pump inhibitor|Na(+)/K(+)-pump inhibitors|Na(+)/K(+)-transporting ATPase (EC 3.6.3.9) inhibitor|Na(+)/K(+)-transporting ATPase (EC 3.6.3.9) inhibitors|Na(+)/K(+)-transporting ATPase inhibitor|Na(+)/K(+)-transporting ATPase inhibitors|sodium pump inhibitor|sodium pump inhibitors|sodium-potassium adenosine triphosphatase inhibitor|sodium-potassium adenosine triphosphatase inhibitors|sodium-potassium pump inhibitor|sodium-potassium pump inhibitors CHEBI:63533 biolink:biological_role_mixin gonadotropin releasing hormone agonist Any drug which binds to gonadotropin-releasing hormone receptors and triggers a response. Graph GnRH agonist|GnRH agonists|GnRH-A|gonadotrophin releasing hormone agonist|gonadotrophin releasing hormone agonists|gonadotropin releasing hormone agonists CHEBI:63673 biolink:biological_role_mixin chemokine receptor 5 antagonist An antogonist that blocks chemokine receptor 5 (CCR5). Graph C-C chemokine receptor 5 antagonist|C-C chemokine receptor 5 antagonists|CCR-5 antagonist|CCR-5 antagonists|CCR5 antagonist|CCR5 antagonists|chemokine receptor 5 antagonists CHEBI:63951 biolink:biological_role_mixin estrogen receptor agonist An agonist at the estrogen receptor. Graph estrogen receptor agonists CHEBI:64018 biolink:biological_role_mixin protein kinase C agonist An agonist that selectively binds to and activates a protein kinase C receptor Graph protein kinase C agonists CHEBI:64047 biolink:biological_role_mixin food additive Any substance which is added to food to preserve or enhance its flavour and/or appearance. Graph food additives CHEBI:64049 biolink:biological_role_mixin food acidity regulator A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents. Graph acidity regulator|acidity regulators|food acidity regulators|pH control agent|pH control agents CHEBI:64106 biolink:biological_role_mixin protein kinase agonist An agonist that selectively binds to and activates a protein kinase receptor. Graph protein kinase agonists CHEBI:64133 biolink:biological_role_mixin EC 2.5.1.58 (protein farnesyltransferase) inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein farnesyltransferase (EC 2.5.1.58), one of the three enzymes in the prenyltransferase group. Graph EC 2.5.1.58 (protein farnesyltransferase) inhibitors|EC 2.5.1.58 inhibitor|EC 2.5.1.58 inhibitors|FTase inhibitor|FTase inhibitors|farnesyl transferase inhibitor|farnesyl transferase inhibitors|farnesyl-diphosphate:protein-cysteine farnesyltransferase inhibitor|farnesyl-diphosphate:protein-cysteine farnesyltransferase inhibitors|farnesyltransferase inhibitor|farnesyltransferase inhibitors|protein farnesyltransferase (EC 2.5.1.58) inhibitor|protein farnesyltransferase (EC 2.5.1.58) inhibitors|protein farnesyltransferase inhibitor|protein farnesyltransferase inhibitors CHEBI:64237 biolink:biological_role_mixin EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor An EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor that interferes with the action of any UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15), preventing formation of N-acetylglucosamine lipid intermediates and glycosylation of newly synthesised glycoproteins. Graph EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitors|EC 2.7.8.15 inhibitor|EC 2.7.8.15 inhibitors|GlcNAc-1-P transferase inhibitor|GlcNAc-1-P transferase inhibitors|N-acetylglucosamine phosphotransferase inhibitor|N-acetylglucosamine transferase inhibitors|N-acetylglucosamine-1-phosphate transferase inhibitor|N-acetylglucosamine-1-phosphate transferase inhibitors|UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitor|UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitors|UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitor|UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitors|UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitor|UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitors|UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitor|UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitors|UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitor|UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitors|UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitor|UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitors|UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitor|UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitors|UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitor|UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitors|chitobiosylpyrophosphoryldolichol synthase inhibitor|chitobiosylpyrophosphoryldolichol synthase inhibitors|dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitor|dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitors|uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitor|uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitors CHEBI:64416 biolink:biological_role_mixin EC 1.3.1.43 (arogenate dehydrogenase) inhibitor An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of arogenate dehydrogenase (EC 1.3.1.43). Graph EC 1.3.1.43 (arogenate dehydrogenase) inhibitors|EC 1.3.1.43 inhibitor|EC 1.3.1.43 inhibitors|L-arogenate:NAD(+) oxidoreductase (decarboxylating) inhibitor|L-arogenate:NAD(+) oxidoreductase (decarboxylating) inhibitors|L-arogenate:NAD+ oxidoreductase (decarboxylating) inhibitor|L-arogenate:NAD+ oxidoreductase (decarboxylating) inhibitors|L-arogenate:NAD+ oxidoreductase inhibitor|L-arogenate:NAD+ oxidoreductase inhibitors|TyrA(a) inhibitor|TyrA(a) inhibitors|arogenate dehydrogenase (EC 1.3.1.43) inhibitor|arogenate dehydrogenase (EC 1.3.1.43) inhibitors|arogenate dehydrogenase inhibitor|arogenate dehydrogenase inhibitors|cyclohexadienyl dehydrogenase inhibitor|cyclohexadienyl dehydrogenase inhibitors CHEBI:64570 biolink:biological_role_mixin EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of glycine hydroxymethyltransferase (EC 2.1.2.1). Graph 5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase inhibitor|5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase inhibitors|EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitors|EC 2.1.2.1 inhibitor|EC 2.1.2.1 inhibitors|L-serine hydroxymethyltransferase inhibitor|L-serine hydroxymethyltransferase inhibitors|L-threonine aldolase inhibitor|L-threonine aldolase inhibitors|allothreonine aldolase inhibitor|allothreonine aldolase inhibitors|glycine hydroxymethyltransferase (EC 2.1.2.1) inhibitor|glycine hydroxymethyltransferase (EC 2.1.2.1) inhibitors|glycine hydroxymethyltransferase inhibitor|glycine hydroxymethyltransferase inhibitors|serine aldolase inhibitor|serine aldolase inhibitors|serine hydroxymethylase inhibitor|serine hydroxymethylase inhibitors|serine hydroxymethyltransferase inhibitor|serine hydroxymethyltransferase inhibitors|serine transhydroxymethylase inhibitor|serine transhydroxymethylase inhibitors|threonine aldolase inhibitor|threonine aldolase inhibitors CHEBI:64571 biolink:biological_role_mixin NMDA receptor agonist An excitatory amino acid agonist which binds to NMDA receptors and triggers a response. Graph N-methyl-D-aspartate receptor agonist|N-methyl-D-aspartate receptor agonists|NMDA receptor agonists|NMDAR agonist|NMDAR agonists CHEBI:64577 biolink:biological_role_mixin flour treatment agent A food additive which is added to flour or dough to improve baking quality and/or colour. Graph dough improver|dough improvers|flour treatment agent|improving agent|improving agents CHEBI:64584 biolink:is_metabolite_of uremic toxin A toxin that accumulates in patients with chronic kidney disease. Graph uremic toxins CHEBI:64588 biolink:biological_role_mixin glycine transporter 1 inhibitor Any glycine transporter inhibitor that interferes with the action of glycine 1 transporters. Graph GlyT1 inhibitor|GlyT1 inhibitors|glycine transporter 1 inhibitors CHEBI:64589 biolink:biological_role_mixin glycine receptor agonist An agonist that binds to and activates glycine receptors Graph glycine receptor agonists CHEBI:64670 biolink:biological_role_mixin EC 1.8.1.9 (thioredoxin reductase) inhibitor An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of thioredoxin reductase (EC 1.8.1.9). Graph EC 1.8.1.9 (thioredoxin reductase) inhibitors|EC 1.8.1.9 inhibitor|EC 1.8.1.9 inhibitors|NADP-thioredoxin reductase inhibitor|NADP-thioredoxin reductase inhibitors|NADPH-thioredoxin reductase inhibitor|NADPH-thioredoxin reductase inhibitors|NADPH2:oxidized thioredoxin oxidoreductase inhibitor|NADPH2:oxidized thioredoxin oxidoreductase inhibitors|TrxR inhibitor|TrxR inhibitors|thioredoxin reductase (EC 1.8.1.9) inhibitor|thioredoxin reductase (EC 1.8.1.9) inhibitors|thioredoxin reductase (NADPH) inhibitor|thioredoxin reductase (NADPH) inhibitors|thioredoxin reductase inhibitor|thioredoxin reductase inhibitors|thioredoxin-disulfide reductase inhibitor|thioredoxin-disulfide reductase inhibitors|thioredoxin:NADP+ oxidoreductase inhibitor|thioredoxin:NADP+ oxidoreductase inhibitors CHEBI:64763 biolink:biological_role_mixin EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that interferes with the action of phosphatidylinositol-specific phospholipase C (EC 3.1.4.11). Graph 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitor|1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitors|1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitor|1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitors|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase inhibitor|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase inhibitors|EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitors|EC 3.1.4.11 inhibitor|EC 3.1.4.11 inhibitors|PI-PLC inhibitor|PI-PLC inhibitors|monophosphatidylinositol phosphodiesterase inhibitor|monophosphatidylinositol phosphodiesterase inhibitors|phosphatidylinositol phospholipase C inhibitor|phosphatidylinositol phospholipase C inhibitors|phosphatidylinositol-specific phospholipase C inhibitor|phosphatidylinositol-specific phospholipase C inhibitors|phosphoinositidase C inhibitor|phosphoinositidase C inhibitors|phosphoinositide phospholipase C (EC 3.1.4.11) inhibitor|phosphoinositide phospholipase C (EC 3.1.4.11) inhibitors|phosphoinositide phospholipase C inhibitor|phosphoinositide phospholipase C inhibitors|triphosphoinositide phosphodiesterase inhibitor|triphosphoinositide phosphodiesterase inhibitors CHEBI:64909 biolink:biological_role_mixin poison Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism. Graph poisonous agent|poisonous agents|poisonous substance|poisonous substances|poisons|toxic agent|toxic agents|toxic substance|toxic substances CHEBI:64911 biolink:biological_role_mixin antimitotic Any compound that inhibits cell division (mitosis). Graph antimitotics|mitosis inhibitor|mitosis inhibitors|mitotic inhibitor|mitotic inhibitors CHEBI:64912 biolink:biological_role_mixin antimycobacterial drug A drug used to treat or prevent infections caused by Mycobacteria, a genus of actinobacteria. Aerobic and nonmotile, members of the genus include the pathogens responsible for causing tuberculosis and leprosy. Graph antimycobacterial agent|antimycobacterial agents|antimycobacterial drugs|antimycobacterials|antimycobacterium CHEBI:64915 biolink:biological_role_mixin antiplasmodial drug An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria. Graph antiplasmodial agent|antiplasmodial agents|antiplasmodial drugs|antiplasmodium agent|antiplasmodium agents|antiplasmodium drug|antiplasmodium drugs CHEBI:64926 biolink:biological_role_mixin serine protease inhibitor Any protease inhibitor that restricts the action of a serine protease. Graph serine protease inhibitors|serine proteinase inhibitor|serine proteinase inhibitors CHEBI:64946 biolink:biological_role_mixin anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. Graph anti-AIDS agent|anti-AIDS agents|anti-HIV agents CHEBI:64947 biolink:biological_role_mixin anti-HIV-1 agent An anti-HIV agent that destroys or inhibits the replication of HIV-1, the more infective and more virulent of the two types of HIV virus. Graph anti-HIV-1 agents|anti-HTLV-III agent|anti-HTLV-III agents|anti-LAV agent|anti-LAV agents CHEBI:64996 biolink:biological_role_mixin EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33). Graph 15-LOX inhibitor|15-LOX inhibitors|15-lipoxygenase inhibitor|15-lipoxygenase inhibitors|EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitors|EC 1.13.11.33 inhibitor|EC 1.13.11.33 inhibitors|arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitor|arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitors|arachidonate 15-lipoxygenase inhibitor|arachidonate 15-lipoxygenase inhibitors|arachidonate:oxygen 15-oxidoreductase inhibitor|arachidonate:oxygen 15-oxidoreductase inhibitors|linoleic acid omega(6)-lipoxygenase inhibitor|linoleic acid omega(6)-lipoxygenase inhibitors|omega(6) lipoxygenase inhibitor|omega(6) lipoxygenase inhibitors CHEBI:65001 biolink:biological_role_mixin EC 3.1.1.3 (triacylglycerol lipase) inhibitor Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of triacylglycerol lipase (EC 3.1.1.3). Graph EC 3.1.1.3 (triacylglycerol lipase) inhibitors|EC 3.1.1.3 inhibitor|EC 3.1.1.3 inhibitors|GEH inhibitor|GEH inhibitors|PPL inhibitor|PPL inhibitors|Tween hydrolase inhibitor|Tween hydrolase inhibitors|Tweenase inhibitor|Tweenase inhibitors|Tweenesterase inhibitor|Tweenesterase inhibitors|butyrinase inhibitor|butyrinase inhibitors|cacordase inhibitor|cacordase inhibitors|capalase L inhibitor|capalase L inhibitors|glycerol ester hydrolase inhibitor|glycerol ester hydrolase inhibitors|glycerol-ester hydrolase inhibitor|glycerol-ester hydrolase inhibitors|heparin releasable hepatic lipase inhibitor|heparin releasable hepatic lipase inhibitors|hepatic lipase inhibitor|hepatic lipase inhibitors|hepatic monoacylglycerol acyltransferase inhibitor|hepatic monoacylglycerol acyltransferase inhibitors|lipase inhibitor|lipase inhibitors|lipazin inhibitor|lipazin inhibitors|liver lipase inhibitor|liver lipase inhibitors|pancreatic lipase inhibitor|pancreatic lipase inhibitors|pancreatic triacylglycerol lipase inhibitor|pancreatic triacylglycerol lipase inhibitors|post-heparin plasma protamine-resistant lipase inhibitor|post-heparin plasma protamine-resistant lipase inhibitors|salt-resistant post-heparin lipase inhibitor|salt-resistant post-heparin lipase inhibitors|steapsin inhibitor|steapsin inhibitors|triacetinase inhibitor|triacetinase inhibitors|triacylglycerol ester hydrolase inhibitor|triacylglycerol ester hydrolase inhibitors|triacylglycerol lipase (EC 3.1.1.3) inhibitor|triacylglycerol lipase (EC 3.1.1.3) inhibitors|triacylglycerol lipase inhibitor|triacylglycerol lipase inhibitors|tributyrase inhibitor|tributyrase inhibitors|tributyrin esterase inhibitor|tributyrin esterase inhibitors|tributyrinase inhibitor|tributyrinase inhibitors|triglyceridase inhibitor|triglyceridase inhibitors|triglyceride hydrolase inhibitor|triglyceride hydrolase inhibitors|triglyceride lipase inhibitor|triglyceride lipase inhibitors|triolein hydrolase inhibitor|triolein hydrolase inhibitors|tween-hydrolysing esterase inhibitor|tween-hydrolyzing esterase inhibitors CHEBI:65053 biolink:biological_role_mixin EC 4.1.1.19 (arginine decarboxylase) inhibitor An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of arginine decarboxylase (EC 4.1.1.19). Graph ADC inhibitor|ADC inhibitors|EC 4.1.1.19 (arginine decarboxylase) inhibitors|EC 4.1.1.19 inhibitor|EC 4.1.1.19 inhibitors|L-arginine carboxy-lyase (agmatine-forming) inhibitor|L-arginine carboxy-lyase (agmatine-forming) inhibitors|L-arginine carboxy-lyase inhibitor|L-arginine carboxy-lyase inhibitors|SpeA inhibitor|SpeA inhibitors|arginine decarboxylase (EC 4.1.1.19) inhibitor|arginine decarboxylase (EC 4.1.1.19) inhibitors|arginine decarboxylase inhibitor|arginine decarboxylase inhibitors CHEBI:65056 biolink:biological_role_mixin EC 3.1.3.11 (fructose-bisphosphatase) inhibitor An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of fructose-bisphosphatase (EC 3.1.3.11). Graph D-fructose 1,6-diphosphatase inhibitor|D-fructose 1,6-diphosphatase inhibitors|D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitor|D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitors|D-fructose-1,6-bisphosphate phosphatase inhibitor|D-fructose-1,6-bisphosphate phosphatase inhibitors|EC 3.1.3.11 (fructose-bisphosphatase) inhibitors|EC 3.1.3.11 inhibitor|EC 3.1.3.11 inhibitors|FBPase inhibitor|FBPase inhibitors|fructose 1,6-bisphosphatase inhibitor|fructose 1,6-bisphosphatase inhibitors|fructose 1,6-bisphosphate 1-phosphatase inhibitor|fructose 1,6-bisphosphate 1-phosphatase inhibitors|fructose 1,6-bisphosphate phosphatase inhibitor|fructose 1,6-bisphosphate phosphatase inhibitors|fructose 1,6-diphosphatase inhibitor|fructose 1,6-diphosphatase inhibitors|fructose 1,6-diphosphate phosphatase inhibitor|fructose 1,6-diphosphate phosphatase inhibitors|fructose bisphosphate phosphatase inhibitor|fructose bisphosphate phosphatase inhibitors|fructose diphosphatase inhibitor|fructose diphosphatase inhibitors|fructose diphosphate phosphatase inhibitor|fructose diphosphate phosphatase inhibitors|fructose-bisphosphatase (EC 3.1.3.11) inhibitor|fructose-bisphosphatase (EC 3.1.3.11) inhibitors|fructose-bisphosphatase inhibitor|fructose-bisphosphatase inhibitors|hexose bisphosphatase inhibitor|hexose bisphosphatase inhibitors|hexose diphosphatase inhibitor CHEBI:65057 biolink:biological_role_mixin adenosine A1 receptor agonist An agonist at the A1 receptor. Graph adenosine A1 receptor agonists CHEBI:65064 biolink:biological_role_mixin EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of cyclopropane fatty acid synthase (EC 2.1.1.79). Graph CFA synthase inhibitor|CFA synthase inhibitors|EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitors|EC 2.1.1.79 inhibitor|EC 2.1.1.79 inhibitors|S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclising) inhibitor|S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclising) inhibitors|S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing) inhibitor|S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing) inhibitors|cyclopropane fatty acid synthase inhibitors|cyclopropane fatty acid synthetase inhibitor|cyclopropane fatty acid synthetase inhibitors|cyclopropane synthase inhibitor|cyclopropane synthase inhibitors|cyclopropane synthetase inhibitor|cyclopropane synthetase inhibitors|cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) inhibitor|cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) inhibitors|cyclopropane-fatty-acyl-phospholipid synthase inhibitor|cyclopropane-fatty-acyl-phospholipid synthase inhibitors|unsaturated-phospholipid methyltransferase inhibitor|unsaturated-phospholipid methyltransferase inhibitors CHEBI:65065 biolink:biological_role_mixin EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of site-specific DNA-methyltransferase (adenine-specific), EC 2.1.1.72. Graph DNA adenine methyltransferase inhibitor|DNA adenine methyltransferase inhibitors|Dam inhibitor|Dam inhibitors|EC 2.1.1.72 (site-specific DNA-methyltransferase (adenine-specific)) inhibitor|EC 2.1.1.72 (site-specific DNA-methyltransferase (adenine-specific)) inhibitors|EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitors|EC 2.1.1.72 inhibitor|EC 2.1.1.72 inhibitors|modification methylase inhibitor|modification methylase inhibitors|restriction-modification system inhibitor|restriction-modification system inhibitors|site-specific DNA-methyltransferase (adenine-specific) (EC 2.1.1.72) inhibitor|site-specific DNA-methyltransferase (adenine-specific) (EC 2.1.1.72) inhibitors|site-specific DNA-methyltransferase (adenine-specific) inhibitor|site-specific DNA-methyltransferase (adenine-specific) inhibitors CHEBI:65207 biolink:biological_role_mixin vascular endothelial growth factor receptor antagonist An antagonist at the vascular endothelial growth factor receptor. Graph VEGF receptor inhibitor|VEGF receptor inhibitors|VEGFR inhibitor|VEGFR inhibitors|vascular endothelial growth factor receptor antagonists|vascular endothelial growth factor receptor inhibitor|vascular endothelial growth factor receptor inhibitors CHEBI:65232 biolink:biological_role_mixin EC 3.4.21.5 (thrombin) inhibitor An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of thrombin (EC 3.4.21.5). Graph E thrombin inhibitor|E thrombin inhibitors|EC 3.4.21.5 (thrombin) inhibitors|EC 3.4.21.5 inhibitor|EC 3.4.21.5 inhibitors|activated blood-coagulation factor II inhibitor|activated blood-coagulation factor II inhibitors|beta-thrombin inhibitor|beta-thrombin inhibitors|blood-coagulation factor IIa inhibitor|blood-coagulation factor IIa inhibitors|factor IIa inhibitor|factor IIa inhibitors|fibrinogenase inhibitor|fibrinogenase inhibitors|gamma-thrombin inhibitor|gamma-thrombin inhibitors|thrombase inhibitor|thrombase inhibitors|thrombin (EC 3.4.21.5) inhibitor|thrombin (EC 3.4.21.5) inhibitors|thrombin inhibitor|thrombin inhibitors|thrombin-C inhibitor|thrombin-C inhibitors|thrombofort inhibitor|thrombofort inhibitors|tropostasin inhibitor|tropostasin inhibitors CHEBI:65255 biolink:biological_role_mixin food preservative Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes. Graph food preservatives CHEBI:65256 biolink:biological_role_mixin antimicrobial food preservative A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299). Graph antimicrobial food preservatives|antimicrobial preservative|antimicrobial preservatives CHEBI:65259 biolink:biological_role_mixin GABA antagonist A compound that inhibits the action of gamma-aminobutyric acid. Graph GABA antagonists|gamma-aminobutyric acid receptor antagonist|gamma-aminobutyric acid receptor antagonists CHEBI:65265 biolink:biological_role_mixin antacid Any substance which is used to neutralise stomach acidity. Graph antacids CHEBI:67072 biolink:biological_role_mixin cannabinoid receptor agonist An agonist that binds to and activates cannabinoid receptors. Graph cannabinoid receptor agonists CHEBI:67114 biolink:biological_role_mixin ryanodine receptor agonist A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction. Graph RyR activator|RyR activators|RyR agonist|RyR agonists|RyRs activator|RyRs agonist|ryanodine receptor activator|ryanodine receptor activators CHEBI:67200 biolink:biological_role_mixin provitamin A A provitamin that can be converted into vitamin A by enzymes from animal tissues. Graph provitamin As CHEBI:68481 biolink:biological_role_mixin mTOR inhibitor A protein kinase inhibitor of the mammalian target of rapamycin (mTOR), a protein that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis and transcription. mTOR inhibitors are used to prevent transplant rejection and in treatment of cancer. Graph mTOR inhibitors|mammalian target of rapamycin inhibitor|mammalian target of rapamycin inhibitors CHEBI:68494 biolink:biological_role_mixin apoptosis inhibitor Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms. Graph Type I cell-death inhibitor|Type I cell-death inhibitors|Type I programmed cell-death inhibitor|Type I programmed cell-death inhibitors|apoptosis inhibitors CHEBI:68495 biolink:biological_role_mixin apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. Graph Type I cell-death inducer|Type I cell-death inducers|Type I programmed cell-death inducer|Type I programmed cell-death inducers|apoptosis inducers CHEBI:68509 biolink:biological_role_mixin glutathione depleting agent A compound which causes a reduction in the levels of glutathione in cells. Graph glutathione depleting agents|glutathione depletion agent|glutathione depletion agents|glutathione depletor|glutathione depletors CHEBI:68563 biolink:biological_role_mixin P2Y12 receptor antagonist An antagonist at the P2Y12 receptor Graph ADP receptor subtype P2Y12 antagonist|ADP receptor subtype P2Y12 antagonists|P2Y12 receptor antagonists|purinergic receptor subtype P2Y12 antagonist|purinergic receptor subtype P2Y12 antagonists CHEBI:70709 biolink:biological_role_mixin progesterone receptor agonist A hormone agonist that binds to and activates progesterone receptors. Graph PR agonist|PR agonists|progesterone receptor agonists CHEBI:70724 biolink:biological_role_mixin cell dedifferentiation agent Any compound which induces a partially or terminally differentiated cell to revert to an earlier developmental stage. Graph cell dedifferentiation agents CHEBI:70725 biolink:biological_role_mixin adenosine A3 receptor antagonist An antagonist at the A3 receptor. Graph adenosine A3 receptor antagonistS CHEBI:70727 biolink:biological_role_mixin topoisomerase inhibitor An EC 5.99.1.* (miscellaneous isomerase) inhibitor that interferes with the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA). Graph topoisomerase inhibitors CHEBI:70728 biolink:biological_role_mixin actin polymerisation inhibitor Any substance that inhibits the polymerisation of the protein actin. Graph actin polymerisation inhibitors|actin polymerization inhibitor|actin polymerization inhibitors|inhibitor of actin polymerization|inhibitors of actin polymerization CHEBI:70770 biolink:biological_role_mixin Aurora kinase inhibitor Any protein kinase inhibitor that inhibits the action of an Aurora kinase (a group of serine/threonine kinases that are essential for cell proliferation). Graph Aurora kinase inhibitors CHEBI:70774 biolink:biological_role_mixin capsaicin receptor antagonist Any substance which blocks the painful sensation of heat caused by capsaicin acting on the TRPV1 ion channel. Graph TRPV1 antagonist|TRPV1 antagonists|TrpV1 antagonist|TrpV1 antagonists|capsaicin antagonist|capsaicin antagonists|capsaicin receptor antagonists|transient receptor potential cation channel subfamily V member 1 antagonist|transient receptor potential cation channel subfamily V member 1 antagonists|vanilloid receptor 1 antagonist|vanilloid receptor 1 antagonists CHEBI:71181 biolink:biological_role_mixin Sir2 inhibitor An EC 3.5.1.98 (histone deacetylase) inhibitor that interferes with the action of Sir2. Graph Sir2 inhibitors CHEBI:71232 biolink:biological_role_mixin adenosine receptor antagonist An antagonist at any adenosine receptor. Graph adenosine receptor antagonists CHEBI:71300 biolink:biological_role_mixin EC 2.* (transferase) inhibitor An enzyme inhibitor that inhibits the action of a transferase (EC 2.*) Graph EC 2 inhibitor|EC 2 inhibitors|EC 2.* (transferase) inhibitors|EC 2.* inhibitor|EC 2.* inhibitors|transferase inhibitor|transferase inhibitors CHEBI:71476 biolink:biological_role_mixin EC 2.3.1.85 (fatty acid synthase) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of fatty acid synthase (EC 2.3.1.85), a multi-enzyme protein involved in fatty acid synthesis. Graph (FAS) inhibitors|EC 2.3.1.85 (fatty acid synthase) inhibitors|EC 2.3.1.85 inhibitor|EC 2.3.1.85 inhibitors|acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) inhibitor|acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) inhibitors|fatty acid synthase (EC 2.3.1.85) inhibitor|fatty acid synthase (EC 2.3.1.85) inhibitors|fatty acid synthase inhibitor|fatty acid synthase inhibitors CHEBI:72316 biolink:is_metabolite_of virulence factor Any toxin secreted by bacteria, viruses, fungi or protozoa enabling them to achieve colonisation of a niche in the host, inhibit or evade the host's immune response, enter and exit cells, or obtain nutrition from the host. Graph virulence factors CHEBI:72768 biolink:biological_role_mixin aryl hydrocarbon receptor agonist An agonist that binds to and activates aryl hydrocarbon receptors (AhRs). Graph AHR agonist|AHR agonists|AhR agonist|AhR agonists|aryl hydrocarbon receptor agonists CHEBI:73181 biolink:biological_role_mixin EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor An EC 1.11.1.* (peroxidases) inhibitor that inhibits the action of L-ascorbate peroxidase (EC 1.11.1.11). Graph EC 1.11.1.11 (L-ascorbate peroxidase) inhibitors|EC 1.11.1.11 inhibitor|EC 1.11.1.11 inhibitors|L-ascorbate peroxidase (EC 1.11.1.11) inhibitor|L-ascorbate peroxidase (EC 1.11.1.11) inhibitors|L-ascorbate peroxidase inhibitor|L-ascorbate peroxidase inhibitors|L-ascorbate:hydrogen-peroxide oxidoreductase inhibitor|L-ascorbate:hydrogen-peroxide oxidoreductase inhibitors|L-ascorbic acid peroxidase inhibitor|L-ascorbic acid peroxidase inhibitors|L-ascorbic acid-specific peroxidase inhibitor|L-ascorbic acid-specific peroxidase inhibitors|ascorbate peroxidase inhibitor|ascorbate peroxidase inhibitors|ascorbic acid peroxidase inhibitor|ascorbic acid peroxidase inhibitors CHEBI:73214 biolink:biological_role_mixin EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of H(+)-transporting two-sector ATPase inhibitor (EC 3.6.3.14). Graph ATP phosphohydrolase (H(+)-transporting) inhibitor|ATP phosphohydrolase (H(+)-transporting) inhibitors|ATP synthase inhibitor|ATP synthase inhibitors|EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitors|EC 3.6.3.14 inhibitor|EC 3.6.3.14 inhibitors|F1-ATPase inhibitor|F1-ATPase inhibitors|FoF1-ATPase inhibitor|FoF1-ATPase inhibitors|H(+)-transporting ATPase inhibitor|H(+)-transporting ATPase inhibitors|H(+)-transporting two-sector ATPase (EC 3.6.3.14) inhibitor|H(+)-transporting two-sector ATPase (EC 3.6.3.14) inhibitors|H(+)-transporting two-sector ATPase inhibitor|H(+)-transporting two-sector ATPase inhibitors|bacterial Ca(2+)/Mg(2+) ATPase inhibitor|bacterial Ca(2+)/Mg(2+) ATPase inhibitors|chloroplast ATPase inhibitor|chloroplast ATPase inhibitors|coupling factors (Fo, F1 and CF1) inhibitor|coupling factors (Fo, F1 and CF1) inhibitors|mitochondrial ATPase inhibitor|mitochondrial ATPase inhibitors CHEBI:73216 biolink:biological_role_mixin EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor Any hydrolase inhibitor that interferes with the action of a hydrolase which acts on acid anhydrides (EC 3.6.*.*). Graph EC 3.6 inhibitor|EC 3.6 inhibitors|EC 3.6.* (hydrolases acting on acid anhydrides) inhibitors|EC 3.6.* inhibitor|EC 3.6.* inhibitors|EC 3.6.*.* inhibitor|EC 3.6.*.* inhibitors|acid anhydride hydrolase inhibitor|acid anhydride hydrolase inhibitors|inhibitor of hydrolase acting on acid anhydride (EC 3.6.*)|inhibitors of hydrolase acting on acid anhydride (EC 3.6.*) CHEBI:73263 biolink:biological_role_mixin cyclooxygenase 3 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 3. Graph COX-3 inhibitor|COX-3 inhibitors|cyclo-oxygenase 3 inhibitor|cyclo-oxygenase 3 inhibitors|cyclooxygenase 3 inhibitors|cyclooxygenase-3 inhibitor|cyclooxygenase-3 inhibitors CHEBI:73311 biolink:biological_role_mixin adenosine receptor agonist An agonist at any adenosine receptor. Graph adenosine receptor agonist CHEBI:73913 biolink:biological_role_mixin antifolate An antimetabolite that impairs the action of folic acids Graph antifolates|folic acid antagonist|folic acid antagonists CHEBI:74213 biolink:biological_role_mixin EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that inhibits the action of ribonucleoside-diphosphate reductase (EC 1.17.4.1). Graph 2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitor|2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitors|ADP reductase inhibitor|ADP reductase inhibitors|CDP reductase inhibitor|CDP reductase inhibitors|EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitors|EC 1.17.4.1 inhibitor|EC 1.17.4.1 inhibitors|RR inhibitor|RR inhibitors|UDP reductase inhibitor|UDP reductase inhibitors|nucleoside diphosphate reductase inhibitor|nucleoside diphosphate reductase inhibitors|ribonucleoside diphosphate reductase inhibitor|ribonucleoside diphosphate reductase inhibitors|ribonucleoside-diphosphate reductase (EC 1.17.4.1) inhibitor|ribonucleoside-diphosphate reductase (EC 1.17.4.1) inhibitors|ribonucleoside-diphosphate reductase inhibitor|ribonucleoside-diphosphate reductase inhibitors|ribonucleotide diphosphate reductase inhibitor|ribonucleotide diphosphate reductase inhibitors|ribonucleotide reductase inhibitor|ribonucleotide reductase inhibitors CHEBI:75190 biolink:biological_role_mixin EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor An EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor that interferes with the action of lysine 2,3-aminomutase (EC 5.4.3.2). Graph EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitors|EC 5.4.3.2 inhibitor|EC 5.4.3.2 inhibitors|L-lysine 2,3-aminomutase inhibitor|L-lysine 2,3-aminomutase inhibitors|lysine 2,3-aminomutase (EC 5.4.3.2) inhibitor|lysine 2,3-aminomutase (EC 5.4.3.2) inhibitors|lysine 2,3-aminomutase inhibitor|lysine 2,3-aminomutase inhibitors CHEBI:75282 biolink:biological_role_mixin ergosterol biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol. Graph ergosterol biosynthesis inhibitors CHEBI:75325 biolink:biological_role_mixin cathartic Any substance that accelerates defecation. Compare with laxatives, which are substances that ease defecation (usually by softening faeces). A substance can be both a laxative and a cathartic. Graph cathartics CHEBI:75380 biolink:biological_role_mixin EC 1.11.1.6 (catalase) inhibitor An inhibitor of peroxidases (EC 1.11.1.*) that inhibits the action of catalase (EC 1.11.1.6). Graph CAT inhibitor|CAT inhibitors|EC 1.11.1.6 (catalase) inhibitors|EC 1.11.1.6 inhibitor|EC 1.11.1.6 inhibitors|caperase inhibitor|caperase inhibitors|catalase (EC 1.11.1.6) inhibitor|catalase (EC 1.11.1.6) inhibitors|catalase inhibitor|catalase inhibitors|catalase-peroxidase inhibitor|catalase-peroxidase inhibitors|equilase inhibitor|equilase inhibitors|hydrogen-peroxide:hydrogen-peroxide oxidoreductase inhibitor|hydrogen-peroxide:hydrogen-peroxide oxidoreductase inhibitors|optidase inhibitor|optidase inhibitors CHEBI:75381 biolink:biological_role_mixin EC 1.11.1.* (peroxidases) inhibitor An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any of the peroxidases (EC 1.11.1.*). Graph EC 1.11.1 inhibitor|EC 1.11.1 inhibitors|EC 1.11.1.* (peroxidase) inhibitor|EC 1.11.1.* (peroxidase) inhibitors|EC 1.11.1.* (peroxidases) inhibitors|EC 1.11.1.* inhibitor|EC 1.11.1.* inhibitors|inhibitor of peroxidases|inhibitors of peroxidases|peroxidases inhibitors CHEBI:75596 biolink:biological_role_mixin EC 5.* (isomerase) inhibitor An enzyme inhibitor that inhibits the action of an isomerase (EC 5.*.*.*). Graph EC 5.* (isomerase) inhibitors|EC 5.* inhibitor|EC 5.* inhibitors|EC 5.*.*.* inhibitor|EC 5.*.*.* inhibitors|isomerase (EC 5.*) inhibitor|isomerase (EC 5.*) inhibitors|isomerase inhibitor|isomerase inhibitors CHEBI:75600 biolink:biological_role_mixin EC 6.3.* (C-N bond-forming ligase) inhibitor A ligase inhibitor that interferes with the action of a C-N bond-forming ligase (EC 6.3.*.*). Graph C--N bond-forming ligase inhibitor|C--N bond-forming ligase inhibitors|C-N bond-forming ligase (EC 6.3.*) inhibitor|C-N bond-forming ligase (EC 6.3.*) inhibitors|C-N bond-forming ligase inhibitor|C-N bond-forming ligase inhibitors|EC 6.3.* (C-N bond-forming ligase) inhibitorS|EC 6.3.* inhibitor|EC 6.3.* inhibitors|EC 6.3.*.* inhibitor|EC 6.3.*.* inhibitors CHEBI:75603 biolink:biological_role_mixin EC 6.* (ligase) inhibitor Any enzyme inhibitor that interferes with the action of a ligase (EC 6.*.*.*). Ligases are enzymes that catalyse the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. Graph EC 6.* (ligase) inhibitors|EC 6.* inhibitor|EC 6.* inhibitors|EC 6.*.*.* inhibitor|EC 6.*.*.* inhibitors|ligase inhibitor|ligase inhibitors CHEBI:75604 biolink:biological_role_mixin EC 6.4.* (C-C bond-forming ligase) inhibitor A ligase inhibitor that interferes with the action of a C-C bond-forming ligase (EC 6.4.*.*). Graph C--C bond-forming ligase inhibitor|C--C bond-forming ligase inhibitors|C-C bond-forming ligase (EC 6.4.*) inhibitor|C-C bond-forming ligase (EC 6.4.*) inhibitorS|C-C bond-forming ligase inhibitor|C-C bond-forming ligase inhibitors|EC 6.4.* (C-C bond-forming ligase) inhibitorS|EC 6.4.* inhibitor|EC 6.4.* inhibitors|EC 6.4.*.* inhibitor|EC 6.4.*.* inhibitors CHEBI:75763 biolink:is_metabolite_of eukaryotic metabolite Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms. Graph eukaryotic metabolites CHEBI:75767 biolink:is_metabolite_of animal metabolite Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals. Graph animal metabolites CHEBI:75768 biolink:is_metabolite_of mammalian metabolite Any animal metabolite produced during a metabolic reaction in mammals. Graph mammalian metabolites CHEBI:75771 biolink:is_metabolite_of mouse metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). Graph Mus musculus metabolite|Mus musculus metabolites|mouse metabolites CHEBI:75772 biolink:is_metabolite_of Saccharomyces cerevisiae metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae). Graph S. cerevisiae metabolite|S. cerevisiae metabolites|S. cerevisiae secondary metabolite|S. cerevisiae secondary metabolites|Saccharomyces cerevisiae metabolites|Saccharomyces cerevisiae secondary metabolites|baker's yeast metabolite|baker's yeast metabolites|baker's yeast secondary metabolite|baker's yeast secondary metabolites CHEBI:75787 biolink:is_metabolite_of prokaryotic metabolite Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea. Graph prokaryotic metabolites CHEBI:76206 biolink:is_metabolite_of xenobiotic metabolite Any metabolite produced by metabolism of a xenobiotic compound. Graph xenobiotic metabolites CHEBI:76395 biolink:biological_role_mixin EC 2.3.1.48 (histone acetyltransferase) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the function of histone acetyltransferase (EC 2.3.1.48). Graph EC 2.3.1.48 (histone acetyltransferase) inhibitors|EC 2.3.1.48 inhibitor|EC 2.3.1.48 inhibitors|HAT inhibitor|HAT inhibitors|acetyl-CoA:histone acetyltransferase inhibitor|acetyl-CoA:histone acetyltransferase inhibitors|histone acetokinase inhibitor|histone acetokinase inhibitors|histone acetylase inhibitor|histone acetylase inhibitors|histone acetyltransferase (EC 2.3.1.48) inhibitor|histone acetyltransferase (EC 2.3.1.48) inhibitors|histone acetyltransferase inhibitor|histone acetyltransferase inhibitors|histone transacetylase inhibitor|histone transacetylase inhibitors|nucleosome-histone acetyltransferase inhibitor|nucleosome-histone acetyltransferase inhibitors CHEBI:76413 biolink:chemical_role_mixin greenhouse gas A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'. Graph greenhouse gases CHEBI:76507 biolink:is_metabolite_of marine metabolite Any metabolite produced during a metabolic reaction in marine macro- and microorganisms. Graph marine metabolites CHEBI:76617 biolink:biological_role_mixin EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that specifically blocks the action of non-specific protein-tyrosine kinase (EC 2.7.10.2). Graph ABL inhibitor|ABL inhibitors|ABL1 inhibitor|ABL1 inhibitors|ABL2 inhibitor|ABL2 inhibitors|ABLL inhibitor|ABLL inhibitors|ACK1 inhibitor|ACK1 inhibitors|ACK2 inhibitor|ACK2 inhibitors|AGMX1 inhibitor|AGMX1 inhibitors|ARG inhibitor|ARG inhibitors|ATK inhibitor|ATK inhibitors|ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific) inhibitor|ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific) inhibitors|BLK inhibitor|BLK inhibitors|BMX inhibitor|BMX inhibitors|BRK inhibitor|BRK inhibitors|BTK inhibitor|BTK inhibitors|BTKL inhibitor|BTKL inhibitors|Bmk inhibitor|Bmk inhibitors|Bruton's tyrosine kinase inhibitor|Bruton's tyrosine kinase inhibitors|Bsk inhibitor|Bsk inhibitors|CAKb inhibitor|CAKb inhibitors|CHK inhibitor|CHK inhibitors|CSK inhibitor|CSK inhibitors|CTK inhibitor|CTK inhibitors|CYL inhibitor|CYL inhibitors|Cdgip inhibitor|Cdgip inhibitors|EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitors|EC 2.7.10.2 inhibitor|EC 2.7.10.2 inhibitors|EMT inhibitor|EMT inhibitors|ETK inhibitor|ETK inhibitors|FAK inhibitor|FAK inhibitors|FAK2 inhibitor|FAK2 inhibitors|FER inhibitor|FER inhibitors|FES inhibitor|FES inhibitors|FGR inhibitor|FGR inhibitors|FPS inhibitor|FPS inhibitors|FRK inhibitor|FRK inhibitors|FYN inhibitor|FYN inhibitors|Fadk inhibitor|Fadk inhibitors|Fert1/2 inhibitor|Fert1/2 inhibitors|HCK inhibitor|HCK inhibitors|HCTK inhibitor|HCTK inhibitors|HYL inhibitor|HYL inhibitors|IMD1 inhibitor|IMD1 inhibitors|ITK inhibitor|ITK inhibitors|IYK inhibitor|IYK inhibitors|JAK1 inhibitor|JAK1 inhibitors|JAK2 inhibitor|JAK2 inhibitors|JAK3 inhibitor|JAK3 inhibitors|JTK1 inhibitor|JTK1 inhibitors|JTK9 inhibitor|JTK9 inhibitors|Janus kinase 1 inhibitor|Janus kinase 1 inhibitors|Janus kinase 2 inhibitor|Janus kinase 2 inhibitors|Janus kinase 3 inhibitor|Janus kinase 3 inhibitors|Janus kinase inhibitor|L-JAK inhibitor|L-JAK inhibitors|LCK inhibitor|LCK inhibitors|LSK inhibitor|LSK inhibitors|LYN inhibitor|LYN inhibitors|MATK inhibitor|MATK inhibitors|Ntk inhibitor|Ntk inhibitors|PKB inhibitor|PKB inhibitors|PSCTK inhibitor|PSCTK inhibitors|PSCTK1 inhibitor|PSCTK1 inhibitors|PSCTK2 inhibitor|PSCTK2 inhibitors|PSCTK4 inhibitor|PSCTK4 inhibitors|PSCTK5 inhibitor|PSCTK5 inhibitors|PTK2 inhibitor|PTK2 inhibitors|PTK2B inhibitor|PTK2B inhibitors|PTK6 inhibitor|PTK6 inhibitors|PYK2 inhibitor|PYK2 inhibitors|RAFTK inhibitor|RAFTK inhibitors|RAK inhibitor|RAK inhibitors|Rlk inhibitor|Rlk inhibitors|SLK inhibitor|SLK inhibitors|SRC inhibitor|SRC inhibitors|SRC2 inhibitor|SRC2 inhibitors|SRK inhibitor|SRK inhibitors|SRM inhibitor|SRM inhibitors|SRMS inhibitor|SRMS inhibitors|STD inhibitor|STD inhibitors|SYK inhibitor|SYK inhibitors|SYN inhibitor|SYN inhibitors|Sik inhibitor|Sik inhibitors|TEC inhibitor|TEC inhibitors|TNK1 inhibitor|TNK1 inhibitors|TXK inhibitor|TXK inhibitors|TYK2 inhibitor|TYK2 inhibitors|TYK3 inhibitor|TYK3 inhibitors|Tck inhibitor|Tck inhibitors|Tsk inhibitor|Tsk inhibitors|YES1 inhibitor|YES1 inhibitors|YK2 inhibitor|YK2 inhibitors|ZAP70 inhibitor|ZAP70 inhibitors|cytoplasmic protein tyrosine kinase inhibitor|cytoplasmic protein tyrosine kinase inhibitors|focal adhesion kinase inhibitor|focal adhesion kinase inhibitors|non-specific protein-tyrosine kinase (EC 2.7.10.2) inhibitor|non-specific protein-tyrosine kinase (EC 2.7.10.2) inhibitors|p60c-src protein tyrosine kinase inhibitor|p60c-src protein tyrosine kinase inhibitors CHEBI:76655 biolink:biological_role_mixin EC 2.1.* (C1-transferase) inhibitor A transferase inhibitor inhibiting the action of transferase of a one-carbon-containing group (EC 2.1.*.*). Graph C1-transferase (EC 2.1.*) inhibitor|C1-transferase (EC 2.1.*) inhibitors|C1-transferase inhibitor|C1-transferase inhibitors|EC 2.1.* (C1-transferase) inhibitors|EC 2.1.* inhibitor|EC 2.1.* inhibitors|one-carbon-containing group transferase inhibitor|one-carbon-containing group transferase inhibitors CHEBI:76661 biolink:biological_role_mixin EC 2.3.* (acyltransferase) inhibitor A transferase inhibitor that interferes with the action of an acyltransferase (EC 2.3.*.*). Graph EC 2.3.* (acyltransferase) inhibitors|EC 2.3.* inhibitor|EC 2.3.* inhibitors|acyltransferase inhibitor|acyltransferase inhibitors CHEBI:76662 biolink:biological_role_mixin EC 2.4.* (glycosyltransferase) inhibitor A transferase inhibitor inhibiting the action of a glycosyltransferase (EC 2.4.*.*). Graph EC 2.4.* (glycosyltransferase) inhibitors|EC 2.4.* inhibitor|EC 2.4.* inhibitors|glycosyltransferase (EC 2.4.*) inhibitor|glycosyltransferase (EC 2.4.*) inhibitors|glycosyltransferase inhibitor|glycosyltransferase inhibitors CHEBI:76663 biolink:biological_role_mixin EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor A transferase inhibitor that inhibits the transfer of an alkyl (other than methyl) or aryl group (EC 2.5.1.*). Graph EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitors|EC 2.5.1.* inhibitor|EC 2.5.1.* inhibitors|alkyl/aryl (non-methyl) transferase inhibitor|alkyl/aryl (non-methyl) transferase inhibitors|non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitor|non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitors|non-methyl alkyl/aryl transferase inhibitor|non-methyl alkyl/aryl transferase inhibitors|non-methyl-alkyl or aryl transferase inhibitor|non-methyl-alkyl or aryl transferase inhibitors CHEBI:76668 biolink:biological_role_mixin EC 2.7.* (P-containing group transferase) inhibitor A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*). Graph EC 2.7.* (P-containing group transferase) inhibitors|EC 2.7.* (phosphorus-containing group transferase) inhibitor|EC 2.7.* (phosphorus-containing group transferase) inhibitors|EC 2.7.* inhibitor|EC 2.7.* inhibitors|phosphorus-containing group transferase (EC 2.7.*) inhibitor|phosphorus-containing group transferase (EC 2.7.*) inhibitors|phosphorus-containing group transferase inhibitor|phosphorus-containing group transferase inhibitors CHEBI:76694 biolink:biological_role_mixin EC 5.3.* (intramolecular oxidoreductase) inhibitor An isomerase inhibitor that interferes with the action of an intramolecular oxidoreductase (EC 5.3.*.*). Graph EC 5.3.* (intramolecular oxidoreductase) inhibitors|intramolecular oxidoreductase (EC 5.3.*) inhibitor|intramolecular oxidoreductase (EC 5.3.*) inhibitors|intramolecular oxidoreductase inhibitor|intramolecular oxidoreductase inhibitors CHEBI:76695 biolink:biological_role_mixin EC 5.4.* (intramolecular transferase) inhibitor An isomerase inhibitor that interferes with the action of an intramolecular transferase (EC 5.4.*.*). Graph EC 5.4.* (intramolecular transferase) inhibitors|intramolecular transferase (EC 5.4.*) inhibitor|intramolecular transferase (EC 5.4.*) inhibitors|intramolecular transferase inhibitor|intramolecular transferase inhibitors CHEBI:76697 biolink:biological_role_mixin EC 5.99.* (other isomerases) inhibitor An isomerase inhibitor that interferes with the action of any member of the group of 'other isomerases' (EC 5.99.*.*). Graph EC 5.99.* (miscellaneous isomerases) inhibitor|EC 5.99.* (miscellaneous isomerases) inhibitors|EC 5.99.* (other isomerase) inhibitor|EC 5.99.* (other isomerase) inhibitors|EC 5.99.* (other isomerases) inhibitors|EC 5.99.* inhibitor|EC 5.99.* inhibitors CHEBI:76710 biolink:biological_role_mixin EC 4.* (lyase) inhibitor An enzyme inhibitor which interferes with the action of a lyase (EC 4.*.*.*). Lyases are enzymes cleaving C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation. Graph EC 4.* (lyase) inhibitors|EC 4.* inhibitor|EC 4.* inhibitors|EC 4.*.*.* inhibitor|EC 4.*.*.* inhibitors|lyase (EC 4.*) inhibitor|lyase (EC 4.*) inhibitorS|lyase inhibitor|lyase inhibitors CHEBI:76711 biolink:biological_role_mixin EC 4.1.* (C-C lyase) inhibitor A lyase inhibitor which inhibits the action of a C-C lyase (EC 4.1.*.*). Graph C-C lyase (EC 4.1.*) inhibitor|C-C lyase (EC 4.1.*) inhibitors|C-C lyase inhibitor|C-C lyase inhibitors|EC 4.1.* (C-C lyase) inhibitors|EC 4.1.* inhibitor|EC 4.1.* inhibitors CHEBI:76712 biolink:biological_role_mixin EC 4.2.* (C-O lyase) inhibitor A lyase inhibitor which inhibits the action of a C-O lyase (EC 4.2.*.*). Graph C-O lyase (EC 4.2.*) inhibitor|C-O lyase (EC 4.2.*) inhibitors|C-O lyase inhibitor|C-O lyase inhibitors|EC 4.2.* (C-O lyase) inhibitors|EC 4.2.* inhibitor|EC 4.2.* inhibitors CHEBI:76713 biolink:biological_role_mixin EC 4.3.* (C-N lyase) inhibitor A lyase inhibitor which inhibits the action of a C-N lyase (EC 4.3.*.*). Graph C-N lyase (EC 4.3.*) inhibitor|C-N lyase (EC 4.3.*) inhibitors|C-N lyase inhibitor|C-N lyase inhibitors|EC 4.3.* (C-N lyase) inhibitors|EC 4.3.* inhibitor|EC 4.3.* inhibitors CHEBI:76725 biolink:biological_role_mixin EC 1.* (oxidoreductase) inhibitor An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*). Graph EC 1.* (oxidoreductase) inhibitors|EC 1.* inhibitor|EC 1.* inhibitors|oxidoreductase (EC 1.*) inhibitor|oxidoreductase (EC 1.*) inhibitors|oxidoreductase inhibitor|oxidoreductase inhibitors CHEBI:76726 biolink:biological_role_mixin EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-OH group of donors (EC 1.1.*.*). Graph EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitors|EC 1.1.* inhibitor|EC 1.1.* inhibitors|inhibitor of oxidoreductase acting on CH-OH group of donor|inhibitor of oxidoreductase acting on CH-OH group of donors|inhibitors of oxidoreductase acting on CH-OH group of donor|inhibitors of oxidoreductase acting on CH-OH group of donors|oxidoreductase acting on donor CH-OH group (EC 1.1.*) inhibitor|oxidoreductase acting on donor CH-OH group (EC 1.1.*) inhibitors|oxidoreductase acting on donor CH-OH group inhibitor|oxidoreductase acting on donor CH-OH group inhibitors CHEBI:76727 biolink:biological_role_mixin EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the aldehyde or oxo group of donors (EC 1.2.*.*). Graph EC 1.2.* (oxidoreductase acting on donor aldehyde or oxo group) inhibitor|EC 1.2.* (oxidoreductase acting on donor aldehyde or oxo group) inhibitors|EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitors|EC 1.2.* inhibitor|EC 1.2.* inhibitors|inhibitor of oxidoreductase acting on aldehyde or oxo group of donor|inhibitor of oxidoreductase acting on aldehyde or oxo group of donors|inhibitor of oxidoreductase acting on aldehyde/oxo group of donor|inhibitor of oxidoreductase acting on aldehyde/oxo group of donors|inhibitors of oxidoreductase acting on aldehyde or oxo group of donor|inhibitors of oxidoreductase acting on aldehyde or oxo group of donors|inhibitors of oxidoreductase acting on aldehyde/oxo group of donor|inhibitors of oxidoreductase acting on aldehyde/oxo group of donors|oxidoreductase acting on donor aldehyde or oxo group (EC 1.2.*) inhibitor|oxidoreductase acting on donor aldehyde or oxo group (EC 1.2.*) inhibitors|oxidoreductase acting on donor aldehyde or oxo group inhibitor|oxidoreductase acting on donor aldehyde or oxo group inhibitors|oxidoreductase acting on donor aldehyde/oxo group (EC 1.2.*) inhibitor|oxidoreductase acting on donor aldehyde/oxo group (EC 1.2.*) inhibitors|oxidoreductase acting on donor aldehyde/oxo group inhibitor|oxidoreductase acting on donor aldehyde/oxo group inhibitors CHEBI:76729 biolink:biological_role_mixin EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-CH group of donors (EC 1.3.*.*). Graph EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitors|EC 1.3.* inhibitor|EC 1.3.* inhibitors|inhibitor of oxidoreductase acting on CH-CH group of donor|inhibitor of oxidoreductase acting on CH-CH group of donors|inhibitors of oxidoreductase acting on CH-CH group of donor|inhibitors of oxidoreductase acting on CH-CH group of donors|oxidoreductase acting on donor CH-CH group (EC 1.3.*) inhibitor|oxidoreductase acting on donor CH-CH group (EC 1.3.*) inhibitors|oxidoreductase acting on donor CH-CH group inhibitor|oxidoreductase acting on donor CH-CH group inhibitors CHEBI:76730 biolink:biological_role_mixin EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH2 group of donors (EC 1.4.*.*). Graph EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor|EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitors|EC 1.4.* inhibitor|EC 1.4.* inhibitors|inhibitor of oxidoreductase acting on CH-NH2 group of donor|inhibitor of oxidoreductase acting on CH-NH2 group of donors|inhibitors of oxidoreductase acting on CH-NH2 group of donor|inhibitors of oxidoreductase acting on CH-NH2 group of donors|oxidoreductase acting on CH-NH2 group of donor inhibitor|oxidoreductase acting on CH-NH2 group of donor inhibitors|oxidoreductase acting on CH-NH2 group of donors (EC 1.4.*) inhibitor|oxidoreductase acting on CH-NH2 group of donors (EC 1.4.*) inhibitors CHEBI:76731 biolink:biological_role_mixin EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH group of donors (EC 1.5.*.*). Graph EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitors|EC 1.5.* inhibitor|EC 1.5.* inhibitors|inhibitor of oxidoreductase acting on CH-NH group of donor|inhibitor of oxidoreductase acting on CH-NH group of donors|inhibitors of oxidoreductase acting on CH-NH group of donor|inhibitors of oxidoreductase acting on CH-NH group of donors|oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitor|oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitors CHEBI:76733 biolink:biological_role_mixin EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on NADH or NADPH (EC 1.6.*.*). Graph EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitors|inhibitor of oxidoreductase acting on NADH or NADPH|inhibitor of oxidoreductase acting on NADH or NADPH (EC 1.6.*)|inhibitors of oxidoreductase acting on NADH or NADPH|inhibitors of oxidoreductase acting on NADH or NADPH (EC 1.6.*)|oxidoreductase acting on NADH or NADPH (EC 1.6.*) inhibitor|oxidoreductase acting on NADH or NADPH (EC 1.6.*) inhibitors|oxidoreductase acting on NADH or NADPH inhibitor|oxidoreductase acting on NADH or NADPH inhibitors CHEBI:76735 biolink:biological_role_mixin EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase of class EC 1.8.*.* (acting on a sulfur group of donors). Graph EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitors|EC 1.8.* inhibitor|EC 1.8.* inhibitors|oxidoreductase acting on a sulfur group of donors (EC 1.8.*) inhibitor|oxidoreductase acting on a sulfur group of donors (EC 1.8.*) inhibitors CHEBI:76736 biolink:biological_role_mixin EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on a heme group of donors (EC 1.9.*.*). Graph EC 1.9.* (oxidoreductase acting on a heme group of donors) inhibitor|EC 1.9.* (oxidoreductase acting on a heme group of donors) inhibitors|EC 1.9.* (oxidoreductase acting on donor heme group) inhibitors|EC 1.9.* inhibitor|EC 1.9.* inhibitors|oxidoreductase acting on a heme group of donors (EC 1.9.*) inhibitor|oxidoreductase acting on a heme group of donors (EC 1.9.*) inhibitors CHEBI:76738 biolink:biological_role_mixin EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on peroxide as donors (EC 1.11.*.*). Graph EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitors|EC 1.11.* (oxidoreductases acting on peroxide as donors) inhibitor|EC 1.11.* (oxidoreductases acting on peroxide as donors) inhibitors|EC 1.11.* inhibitor|EC 1.11.* inhibitors|oxidoreductase acting on peroxide as donors (EC 1.11.*) inhibitor|oxidoreductase acting on peroxide as donors (EC 1.11.*) inhibitors|oxidoreductases acting on peroxide as donors (EC 1.11.*) inhibitor|oxidoreductases acting on peroxide as donors (EC 1.11.*) inhibitors CHEBI:76740 biolink:biological_role_mixin EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases), EC 1.13.*.*. Graph EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitors|EC 1.13.* inhibitor|EC 1.13.* inhibitors|oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) (EC 1.13.*) inhibitor|oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) (EC 1.13.*) inhibitors|oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) inhibitor|oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) inhibitors CHEBI:76741 biolink:biological_role_mixin EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.14.*.*). Graph EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitors|EC 1.14.* inhibitor|EC 1.14.* inhibitors|inhibitor of oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)|inhibitor of oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)|inhibitors of oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)|inhibitors of oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)|oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitor|oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitors|oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen inhibitor|oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen inhibitors CHEBI:76744 biolink:biological_role_mixin EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on CH or CH2 (EC 1.17.*.*). Graph EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitors|EC 1.17.* inhibitor|EC 1.17.* inhibitors|oxidoreductase acting on CH or CH2 (EC 1.17.*) inhibitor|oxidoreductase acting on CH or CH2 (EC 1.17.*) inhibitors|oxidoreductase acting on CH or CH2 inhibitor|oxidoreductase acting on CH or CH2 inhibitors CHEBI:76759 biolink:biological_role_mixin EC 3.* (hydrolase) inhibitor Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*). Graph EC 3.* (hydrolase) inhibitors|EC 3.* inhibitor|EC 3.* inhibitors|EC 3.*.*.* inhibitor|EC 3.*.*.* inhibitors|hydrolase (EC 3.*) inhibitor|hydrolase (EC 3.*) inhibitors|hydrolase inhibitor|hydrolase inhibitors CHEBI:76760 biolink:biological_role_mixin EC 3.1.* (ester hydrolase) inhibitor A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*). Graph EC 3.1.* (ester hydrolase) inhibitors|EC 3.1.* inhibitor|EC 3.1.* inhibitors|ester hydrolase (EC 3.1.*) inhibitor|ester hydrolase (EC 3.1.*) inhibitors|ester hydrolase inhibitor|ester hydrolase inhibitors CHEBI:76761 biolink:biological_role_mixin EC 3.2.* (glycosylase) inhibitor A hydrolase inhibitor that interferes with the action of any glycosylase (EC 3.2.*.*). Graph EC 3.2.* (glycosylase) inhibitors|EC 3.2.* inhibitor|EC 3.2.* inhibitors|glycosylase (EC 3.2.*) inhibitor|glycosylase (EC 3.2.*) inhibitors|glycosylase inhibitor|glycosylase inhibitors CHEBI:76764 biolink:biological_role_mixin EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*). Graph EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor|EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors|EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor|EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors|EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors|EC 3.5.* inhibitor|EC 3.5.* inhibitors CHEBI:76773 biolink:biological_role_mixin EC 3.1.1.* (carboxylic ester hydrolase) inhibitor An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a carboxylic ester hydrolase (EC 3.1.1.*). Graph EC 3.1.1.* (carboxylic ester hydrolase) inhibitors|EC 3.1.1.* inhibitor|EC 3.1.1.* inhibitors|carboxylic ester hydrolase (EC 3.1.1.*) inhibitor|carboxylic ester hydrolase (EC 3.1.1.*) inhibitors CHEBI:76775 biolink:biological_role_mixin EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*). Graph EC 3.1.3.* (phosphoric monoester hydrolase) inhibitors|EC 3.1.3.* inhibitor|EC 3.1.3.* inhibitors|inhibitor of phosphoric monoester hydrolase|inhibitor of phosphoric monoester hydrolase (EC 3.1.3.*)|inhibitors of phosphoric monoester hydrolase|inhibitors of phosphoric monoester hydrolase (EC 3.1.3.*)|phosphoric monoester hydrolase (EC 3.1.3.*) inhibitor|phosphoric monoester hydrolase (EC 3.1.3.*) inhibitors|phosphoric monoester hydrolase inhibitor|phosphoric monoester hydrolase inhibitors CHEBI:76779 biolink:biological_role_mixin EC 3.4.21.26 (prolyl oligopeptidase) inhibitor Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26). Graph EC 3.4.21.26 (prolyl oligopeptidase) inhibitors|EC 3.4.21.26 inhibitor|EC 3.4.21.26 inhibitors|endoprolylpeptidase inhibitor|endoprolylpeptidase inhibitors|post-proline cleaving enzyme inhibitor|post-proline cleaving enzyme inhibitors|post-proline endopeptidase inhibitor|post-proline endopeptidase inhibitors|proline endopeptidase inhibitor|proline endopeptidase inhibitors|proline-specific endopeptidase inhibitor|proline-specific endopeptidase inhibitors|prolyl endopeptidase inhibitor|prolyl endopeptidase inhibitors|prolyl oligopeptidase (EC 3.4.21.26) inhibitor|prolyl oligopeptidase (EC 3.4.21.26) inhibitors|prolyl oligopeptidase inhibitor CHEBI:76789 biolink:biological_role_mixin EC 2.4.1.* (hexosyltransferase) inhibitor An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any hexosyltransferase (EC 2.4.1.*). Graph EC 2.4.1.* (hexosyltransferase) inhibitors|EC 2.4.1.* inhibitor|EC 2.4.1.* inhibitors|hexosyltransferase (EC 2.4.1.*) inhibitor|hexosyltransferase (EC 2.4.1.*) inhibitors|hexosyltransferase inhibitor|hexosyltransferase inhibitors CHEBI:76790 biolink:biological_role_mixin EC 2.4.2.* (pentosyltransferase) inhibitor An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any pentosyltransferase (EC 2.4.2.*). Graph EC 2.4.2.* (pentosyltransferase) inhibitors|EC 2.4.2.* inhibitor|EC 2.4.2.* inhibitors|pentosyltransferase (EC 2.4.2.*) inhibitor|pentosyltransferase (EC 2.4.2.*) inhibitors|pentosyltransferase inhibitor|pentosyltransferase inhibitors CHEBI:76796 biolink:biological_role_mixin EC 3.4.22.* (cysteine endopeptidase) inhibitor An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any cysteine endopeptidase (EC 3.4.22.*). Graph EC 3.4.22.* (cysteine endopeptidase) inhibitors|EC 3.4.22.* inhibitor|EC 3.4.22.* inhibitors|cysteine endopeptidase (EC 3.4.22.*) inhibitor|cysteine endopeptidase (EC 3.4.22.*) inhibitors|cysteine endopeptidase inhibitor|cysteine endopeptidase inhibitors CHEBI:76797 biolink:biological_role_mixin EC 2.5.1.18 (glutathione transferase) inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of a glutathione transferase (EC 2.5.1.18). Graph EC 2.5.1.18 (glutathione transferase) inhibitors|EC 2.5.1.18 inhibitor|EC 2.5.1.18 inhibitors|RX:glutathione R-transferase inhibitor|RX:glutathione R-transferase inhibitors|S-(hydroxyalkyl)glutathione lyase inhibitor|S-(hydroxyalkyl)glutathione lyase inhibitors|glutathione S-alkyl transferase inhibitor|glutathione S-alkyl transferase inhibitors|glutathione S-alkyltransferase inhibitor|glutathione S-alkyltransferase inhibitors|glutathione S-aralkyltransferase inhibitor|glutathione S-aralkyltransferase inhibitors|glutathione S-aryltransferase inhibitor|glutathione S-aryltransferase inhibitors|glutathione S-transferase inhibitor|glutathione S-transferase inhibitors|glutathione transferase (EC 2.5.1.18) inhibitor|glutathione transferase (EC 2.5.1.18) inhibitors|glutathione transferase inhibitor|glutathione transferase inhibitors CHEBI:76807 biolink:biological_role_mixin EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*). Graph EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors|EC 3.5.1.* inhibitor|EC 3.5.1.* inhibitors|non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor|non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors CHEBI:76808 biolink:biological_role_mixin EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*). Graph EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitors|EC 3.5.2.* inhibitor|EC 3.5.2.* inhibitors|non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*) inhibitor|non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*) inhibitors|non-peptide cyclic amide C-N hydrolase inhibitor|non-peptide cyclic amide C-N hydrolase inhibitors CHEBI:76812 biolink:biological_role_mixin EC 2.7.11.* (protein-serine/threonine kinase) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*). Graph EC 2.7.11.* (protein-serine/threonine kinase) inhibitors|EC 2.7.11.* inhibitor|EC 2.7.11.* inhibitors|protein-serine/threonine kinase (EC 2.7.11.*) inhibitor|protein-serine/threonine kinase (EC 2.7.11.*) inhibitors|protein-serine/threonine kinase inhibitor|protein-serine/threonine kinase inhibitors CHEBI:76815 biolink:biological_role_mixin EC 2.7.7.* (nucleotidyltransferase) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*). Graph EC 2.7.7.* (nucleotidyltransferase) inhibitors|inhibitor of nucleotidyltransferases|inhibitor of nucleotidyltransferases (EC 2.7.7.*)|inhibitors of nucleotidyltransferases|inhibitors of nucleotidyltransferases (EC 2.7.7.*)|nucleotidyltransferase (EC 2.7.7.*) inhibitor|nucleotidyltransferase (EC 2.7.7.*) inhibitors|nucleotidyltransferase inhibitor|nucleotidyltransferase inhibitors CHEBI:76816 biolink:biological_role_mixin EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with any enzyme in the EC 2.7.8.* (transferases for other substituted phosphate groups) category. Graph EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitors|EC 2.7.8.* inhibitor|EC 2.7.8.* inhibitors CHEBI:76817 biolink:biological_role_mixin EC 2.7.10.* (protein-tyrosine kinase) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-tyrosine kinase (EC 2.7.10.*). Graph EC 2.7.10.* (protein-tyrosine kinase) inhibitors|EC 2.7.10.* inhibitor|EC 2.7.10.* inhibitors|protein-tyrosine kinase (EC 2.7.10.*) inhibitor|protein-tyrosine kinase (EC 2.7.10.*) inhibitors|protein-tyrosine kinase inhibitor|protein-tyrosine kinase inhibitors CHEBI:76823 biolink:biological_role_mixin EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of any acid-ammonia (or amine) ligase (EC 6.3.1.*). Graph EC 6.3.1.* (acid-ammonia/amine ligase) inhibitors|EC 6.3.1.* inhibitor|EC 6.3.1.* inhibitors|acid-ammonia (or amine) ligase inhibitor|acid-ammonia (or amine) ligase inhibitors CHEBI:76824 biolink:biological_role_mixin EC 6.4.1.* (carboxylase) inhibitor An EC 6.4.* (C-C bond-forming ligase) inhibitor that interferes with the action of a carboxylating enzyme (EC 6.4.1.*). Graph EC 6.4.1.* (C-C bond forming ligase) inhibitor|EC 6.4.1.* (C-C bond forming ligase) inhibitors|EC 6.4.1.* (C-C bond-forming ligase) inhibitors|EC 6.4.1.* (carboxylase) inhibitors|EC 6.4.1.* inhibitor|EC 6.4.1.* inhibitors|inhibitor of ligases forming C-C bonds|inhibitor of ligases forming C-C bonds (EC 6.4.1.*)|inhibitors of ligases forming C-C bonds|inhibitors of ligases forming C-C bonds (EC 6.4.1.*) CHEBI:76829 biolink:biological_role_mixin EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor An EC 5.4.* (intramolecular transferase) inhibitor that interferes with the activity of any intramolecular transferase transferring amino groups (EC 5.4.3.*). Graph EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitors|EC 5.4.3.* inhibitor|EC 5.4.3.* inhibitors|inhibitor of intramolecular transferase transferring amino groups|inhibitor of intramolecular transferase transferring amino groups (EC 5.4.3.*)|inhibitors of intramolecular transferase transferring amino groups|inhibitors of intramolecular transferase transferring amino groups (EC 5.4.3.*) CHEBI:76830 biolink:biological_role_mixin EC 5.99.1.* (miscellaneous isomerase) inhibitor An EC 5.99.* (other isomerases) inhibitor that interferes with the activity of any enzyme in the EC 5.99.1.* class. Graph EC 5.99.1.* (miscellaneous isomerase) inhibitors|EC 5.99.1.* inhibitor|EC 5.99.1.* inhibitors CHEBI:76832 biolink:biological_role_mixin EC 4.3.1.* (ammonia-lyase) inhibitor An EC 4.3.* (C-N lyase) inhibitor that interferes with the action of any ammonia-lyase (EC 4.3.1.*). Graph EC 4.3.1.* (ammonia-lyase) inhibitors|EC 4.3.1.* (ammonia-lyases) inhibitor|EC 4.3.1.* (ammonia-lyases) inhibitors|EC 4.3.1.* inhibitor|EC 4.3.1.* inhibitors|ammonia-lyase (EC 4.3.1.*) inhibitor|ammonia-lyase (EC 4.3.1.*) inhibitors|ammonia-lyase inhibitor|ammonia-lyase inhibitors CHEBI:76834 biolink:biological_role_mixin EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor An EC 2.5.* (transferase) inhibitor that inhibits the action of any transferase that transfers an alkyl (other than methyl) or aryl group (EC 2.5.*). Graph EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitors|EC 2.5.* inhibitor|EC 2.5.* inhibitors|non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitor|non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitors CHEBI:76835 biolink:biological_role_mixin EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that uses NAD(+) or NADP(+) as acceptor (EC 1.1.1.*). Graph EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+)acceptor) inhibitors|EC 1.1.1.* inhibitor|EC 1.1.1.* inhibitors|oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor (EC 1.1.1.*) inhibitor|oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor (EC 1.1.1.*) inhibitors CHEBI:76836 biolink:biological_role_mixin EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.1.3.*). Graph EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitors|EC 1.1.3.* inhibitor|EC 1.1.3.* inhibitors|oxidoreductase acting on donor CH-OH group, oxygen as acceptor (EC 1.1.3.*) inhibitor|oxidoreductase acting on donor CH-OH group, oxygen as acceptor (EC 1.1.3.*) inhibitors CHEBI:76837 biolink:biological_role_mixin EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor An EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor that inhibits the action of any oxidoreductase incorporating 2 atoms of oxygen (EC 1.13.11.*). Graph EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitors|EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitor|EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitors|EC 1.13.11.* inhibitor|EC 1.13.11.* inhibitors|oxidoreductase acting on single donors and incorporating 2 atoms of oxygen (EC 1.13.11.*) inhibitor|oxidoreductase acting on single donors and incorporating 2 atoms of oxygen (EC 1.13.11.*) inhibitors CHEBI:76838 biolink:biological_role_mixin EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using reduced flavin or flavoprotein as donor (EC 1.14.14.*). Graph EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors|EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor|EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors|EC 1.14.14.* inhibitor|EC 1.14.14.* inhibitors|oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor (EC 1.14.14.*) inhibitor|oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor (EC 1.14.14.*) inhibitors CHEBI:76840 biolink:biological_role_mixin EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any enzyme in the EC 1.14.99.* (miscellaneous) category. Graph EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitors|EC 1.14.99.* inhibitor|EC 1.14.99.* inhibitors|miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.99.*) inhibitor|miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.99.*) inhibitors CHEBI:76841 biolink:biological_role_mixin EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using NADH or NADPH as one donor (EC 1.14.13.*). Graph EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitors|EC 1.14.13.* inhibitor|EC 1.14.13.* inhibitors|oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor (EC 1.14.13.*) inhibitor|oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor (EC 1.14.13.*) inhibitors CHEBI:76848 biolink:biological_role_mixin EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitor An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that interferes with the activity of any such enzyme that uses a disulfide as acceptor (EC 1.17.4.*). Graph EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitors|EC 1.17.4.* inhibitor|EC 1.17.4.* inhibitors|oxidoreductase acting on CH or CH2 with a disulfide as acceptor (EC 1.17.4.*) inhibitor|oxidoreductase acting on CH or CH2 with a disulfide as acceptor (EC 1.17.4.*) inhibitors CHEBI:76853 biolink:biological_role_mixin EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor An EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.2.3.*). Graph EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitors|EC 1.2.3.* inhibitor|EC 1.2.3.* inhibitors|oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor (EC 1.2.3.*) inhibitor|oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor (EC 1.2.3.*) inhibitors CHEBI:76857 biolink:biological_role_mixin EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.3.1.*). Graph EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor) inhibitor|EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor) inhibitors|EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor|EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitors|EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitors|EC 1.3.1.* inhibitor|EC 1.3.1.* inhibitors|oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor (EC 1.3.1.*) inhibitor|oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor (EC 1.3.1.*) inhibitors CHEBI:76861 biolink:biological_role_mixin EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.4.3.*). Graph EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitors|EC 1.4.3.* inhibitor|EC 1.4.3.* inhibitors|oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor (EC 1.4.3.*) inhibitor|oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor (EC 1.4.3.*) inhibitors CHEBI:76863 biolink:biological_role_mixin EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor An EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.5.1.*). Graph EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitors|EC 1.5.1.* inhibitor|EC 1.5.1.* inhibitors|oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitor|oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitors CHEBI:76866 biolink:biological_role_mixin EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor An EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor that interferes with the action of any such enzyme using a quinone or similar as acceptor (EC 1.6.5.*). Graph EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitors|EC 1.6.5.* inhibitor|EC 1.6.5.* inhibitors|oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor (EC 1.6.5.*) inhibitor|oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor (EC 1.6.5.*) inhibitors CHEBI:76869 biolink:biological_role_mixin EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor An EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.8.1.*). Graph EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitors|EC 1.8.1.* inhibitor|EC 1.8.1.* inhibitors|oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor (EC 1.8.1.*) inhibitor|oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor (EC 1.8.1.*) inhibitors CHEBI:76870 biolink:biological_role_mixin EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor An EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.9.3.*). Graph EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitors|EC 1.9.3.* inhibitor|EC 1.9.3.* inhibitors|oxidoreductase acting on donor heme group, oxygen as acceptor (EC 1.9.3.*) inhibitor|oxidoreductase acting on donor heme group, oxygen as acceptor (EC 1.9.3.*) inhibitors CHEBI:76871 biolink:biological_role_mixin EC 2.1.1.* (methyltransferases) inhibitor An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any methyltransferase (EC 2.1.1.*). Graph EC 2.1.1.* (methyltransferase) inhibitor|EC 2.1.1.* (methyltransferase) inhibitors|EC 2.1.1.* (methyltransferases) inhibitors|EC 2.1.1.* inhibitor|EC 2.1.1.* inhibitors|methyltransferase (EC 2.1.1.*) inhibitor|methyltransferase (EC 2.1.1.*) inhibitors CHEBI:76874 biolink:biological_role_mixin EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any hydroxymethyl-, formyl- and related transferase (EC 2.1.2.*). Graph EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitors|EC 2.1.2.* inhibitor|EC 2.1.2.* inhibitors|hydroxymethyl-, formyl- and related transferases (EC 2.1.2.*) inhibitor|hydroxymethyl-, formyl- and related transferases (EC 2.1.2.*) inhibitors CHEBI:76878 biolink:biological_role_mixin EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor An EC 2.3.* (acyltransferase) inhibitor that inhibits the action of any acyltransferase transferring groups other than amino-acyl groups (EC 2.3.1.*). Graph EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitors|EC 2.3.1.* inhibitor|EC 2.3.1.* inhibitors|acyltransferase transferring other than amino-acyl group EC 2.3.1.* inhibitor|acyltransferase transferring other than amino-acyl group EC 2.3.1.* inhibitors CHEBI:76881 biolink:biological_role_mixin EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with an alcohol group as acceptor (EC 2.7.1.*). Graph EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitors|EC 2.7.1.* inhibitor|EC 2.7.1.* inhibitors|phosphotransferases with an alcohol group as acceptor (EC 2.7.1.*) inhibitor|phosphotransferases with an alcohol group as acceptor (EC 2.7.1.*) inhibitors CHEBI:76895 biolink:biological_role_mixin EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme that catalyses transmembrane movement of substances (EC 3.6.3.*). Graph EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitors|EC 3.6.3.* inhibitor|EC 3.6.3.* inhibitors|acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitor|acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitors CHEBI:76898 biolink:biological_role_mixin EC 1.14.14.1 (unspecific monooxygenase) inhibitor An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of an unspecified monooxygenase (EC 1.14.14.1). Graph EC 1.14.14.1 (unspecific monooxygenase) inhibitors|EC 1.14.14.1 inhibitor|EC 1.14.14.1 inhibitors|aryl hydrocarbon hydroxylase inhibitor|aryl hydrocarbon hydroxylase inhibitors|aryl-4-monooxygenase inhibitor|aryl-4-monooxygenase inhibitors|flavoprotein monooxygenase inhibitor|flavoprotein monooxygenase inhibitors|flavoprotein-linked monooxygenase inhibitor|flavoprotein-linked monooxygenase inhibitors|microsomal P-450 inhibitor|microsomal P-450 inhibitors|microsomal monooxygenase inhibitor|microsomal monooxygenase inhibitors|substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidising) inhibitor|substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidising) inhibitors|unspecific monooxygenase (EC 1.14.14.1) inhibitor|unspecific monooxygenase (EC 1.14.14.1) inhibitors|unspecific monooxygenase inhibitor|unspecific monooxygenase inhibitors|xenobiotic monooxygenase inhibitor|xenobiotic monooxygenase inhibitors CHEBI:76906 biolink:biological_role_mixin EC 4.1.1.* (carboxy-lyase) inhibitor An EC 4.1.* (C-C lyase) inhibitor that interferes with the action of any carboxy-lyase (EC 4.1.1.*). Graph EC 4.1.1.* (carboxy-lyase) inhibitors|EC 4.1.1.* inhibitor|EC 4.1.1.* inhibitors|carboxy-lyase (EC 4.1.1.*) inhibitor|carboxy-lyase (EC 4.1.1.*) inhibitors|carboxy-lyases (EC 4.1.1.*) inhibitor|carboxy-lyases (EC 4.1.1.*) inhibitors CHEBI:76907 biolink:biological_role_mixin EC 4.2.1.* (hydro-lyases) inhibitor An EC 4.2.* (C-O lyase) inhibitor that interferes with the action of any hydro-lyase (EC 4.2.1.*). Graph EC 4.2.1.* (hydro-lyase) inhibitor|EC 4.2.1.* (hydro-lyase) inhibitors|EC 4.2.1.* (hydro-lyases) inhibitors|EC 4.2.1.* inhibitor|EC 4.2.1.* inhibitors|hydro-lyase (EC 4.2.1.*) inhibitor|hydro-lyase (EC 4.2.1.*) inhibitors CHEBI:76924 biolink:is_metabolite_of plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. Graph plant metabolites|plant secondary metabolites CHEBI:76932 biolink:biological_role_mixin pathway inhibitor An enzyme inhibitor that interferes with one or more steps in a metabolic pathway. Graph metabolic pathway inhibitor|metabolic pathway inhibitors|pathway inhibitors CHEBI:76946 biolink:is_metabolite_of fungal metabolite Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds. Graph fungal metabolites CHEBI:76956 biolink:is_metabolite_of Aspergillus metabolite Any fungal metabolite produced during a metabolic reaction in the mould, Aspergillus. Graph Aspergillus metabolites CHEBI:76960 biolink:is_metabolite_of Chaetomium metabolite Any fungal metabolite produced during a metabolic reaction in the mould, Chaetomium. Graph Chaetomium metabolites CHEBI:76964 biolink:is_metabolite_of Penicillium metabolite Any fungal metabolite produced during a metabolic reaction in Penicillium. Graph Penicillium metabolites CHEBI:76967 biolink:is_metabolite_of human xenobiotic metabolite Any human metabolite produced by metabolism of a xenobiotic compound in humans. Graph human xenobiotic metabolites CHEBI:76969 biolink:is_metabolite_of bacterial metabolite Any prokaryotic metabolite produced during a metabolic reaction in bacteria. Graph CHEBI:76971 biolink:is_metabolite_of Escherichia coli metabolite Any bacterial metabolite produced during a metabolic reaction in Escherichia coli. Graph E.coli metabolite|E.coli metabolites|Escherichia coli metabolites CHEBI:76976 biolink:is_metabolite_of bacterial xenobiotic metabolite Any bacterial metabolite produced by metabolism of a xenobiotic compound in bacteria. Graph bacterial xenobiotic metabolites CHEBI:76988 biolink:biological_role_mixin xenoestrogen A synthetic or semi-synthetic compound that has oestrogenic activity. Graph xenoestrogens CHEBI:76990 biolink:biological_role_mixin mycoestrogen Any compound produced by a fungus that happens to have estrogenic activity. Graph mycoestrogens CHEBI:77022 biolink:biological_role_mixin EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor An EC 2.3.* (acyltransferase) inhibitor that interferes with the action of an acyltransferase which converts the acyl group to an alkyl group on transfer (EC 2.3.3.*). Graph EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitors|EC 2.3.3.* inhibitor|EC 2.3.3.* inhibitors|acyltransferase converting acyl to alkyl group on transfer (EC 2.3.3.*) inhibitor|acyltransferase converting acyl to alkyl group on transfer (EC 2.3.3.*) inhibitors CHEBI:77023 biolink:biological_role_mixin EC 2.3.3.1 [citrate (Si)-synthase] inhibitor An EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor that interferes with the action of citrate (Si)-synthase, EC 2.3.3.1. Graph (R)-citrate synthase inhibitor|(R)-citrate synthase inhibitors|EC 2.3.3.1 (citrate (Si)-synthase) inhibitor|EC 2.3.3.1 (citrate (Si)-synthase) inhibitors|EC 2.3.3.1 [citrate (Si)-synthase] inhibitors|EC 2.3.3.1 inhibitor|EC 2.3.3.1 inhibitors|acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming] inhibitor|acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming] inhibitors|citrate (Si)-synthase (EC 2.3.3.1) inhibitor|citrate (Si)-synthase (EC 2.3.3.1) inhibitors|citrate condensing enzyme inhibitor|citrate condensing enzyme inhibitors|citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA] inhibitor|citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA] inhibitors|citrate oxaloacetate-lyase, CoA-acetylating inhibitor|citrate oxaloacetate-lyase, CoA-acetylating inhibitors|citrate synthase inhibitor|citrate synthase inhibitors|citrate synthetase inhibitor|citrate synthetase inhibitors|citric synthase inhibitor|citric synthase inhibitors|citric-condensing enzyme inhibitor|citric-condensing enzyme inhibitors|citrogenase inhibitor|citrogenase inhibitors|condensing enzyme inhibitor|condensing enzyme inhibitors|oxalacetic transacetase inhibitor|oxalacetic transacetase inhibitors|oxaloacetate transacetase inhibitor|oxaloacetate transacetase inhibitors CHEBI:77024 biolink:biological_role_mixin EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of 4-nitrophenylphosphatase (EC 3.1.3.41). Graph 4-nitrophenylphosphatase (EC 3.1.3.41) inhibitor|4-nitrophenylphosphatase (EC 3.1.3.41) inhibitors|4-nitrophenylphosphate phosphohydrolase inhibitor|4-nitrophenylphosphate phosphohydrolase inhibitors|EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitors|EC 3.1.3.41 inhibitor|EC 3.1.3.41 inhibitors|Ecto-p-nitrophenyl phosphatase inhibitor|Ecto-p-nitrophenyl phosphatase inhibitors|K-pNPPase inhibitor|K-pNPPase inhibitors|NPPase inhibitor|NPPase inhibitors|PNPPase inhibitor|PNPPase inhibitors|nitrophenyl phosphatase inhibitor|nitrophenyl phosphatase inhibitors|p-nitrophenylphosphatase inhibitor|p-nitrophenylphosphatase inhibitors|p-nitrophenylphosphate phosphohydrolase inhibitor|p-nitrophenylphosphate phosphohydrolase inhibitors|para-nitrophenyl phosphatase inhibitor|para-nitrophenyl phosphatase inhibitors|xK-pNPPase inhibitors CHEBI:77089 biolink:biological_role_mixin EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49). Graph EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitors|EC 2.5.1.49 inhibitor|EC 2.5.1.49 inhibitors|O-acetyl-L-homoserine acetate-lyase (adding methanethiol) inhibitor|O-acetyl-L-homoserine acetate-lyase (adding methanethiol) inhibitors|O-acetyl-L-homoserine sulfhydrolase inhibitor|O-acetyl-L-homoserine sulfhydrolase inhibitors|O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase inhibitor|O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase inhibitors|O-acetylhomoserine (thiol)-lyase inhibitor|O-acetylhomoserine (thiol)-lyase inhibitors|O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49) inhibitor|O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49) inhibitors|O-acetylhomoserine aminocarboxypropyltransferase inhibitor|O-acetylhomoserine aminocarboxypropyltransferase inhibitors|O-acetylhomoserine sulfhydrolase inhibitor|O-acetylhomoserine sulfhydrolase inhibitors|methionine synthase inhibitor|methionine synthase inhibitors CHEBI:77090 biolink:biological_role_mixin EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of serine-sulfate ammonia-lyase (EC 4.3.1.10). Graph (L-SOS)lyase inhibitor|(L-SOS)lyase inhibitors|EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitors|EC 4.3.1.10 inhibitor|EC 4.3.1.10 inhibitors|L-serine-O-sulfate ammonia-lyase (pyruvate-forming) inhibitor|L-serine-O-sulfate ammonia-lyase (pyruvate-forming) inhibitors|serine-sulfate ammonia-lyase (EC 4.3.1.10) inhibitor|serine-sulfate ammonia-lyase (EC 4.3.1.10) inhibitors|serine-sulfate ammonia-lyase inhibitor|serine-sulfate ammonia-lyase inhibitors CHEBI:77102 biolink:biological_role_mixin EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using a quinone or related compound as acceptor (EC 1.3.5.*). Graph EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitors|EC 1.3.5.* inhibitor|EC 1.3.5.* inhibitors|inhibitor of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor|inhibitor of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*)|inhibitors of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor|inhibitors of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*)|oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) inhibitor|oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) inhibitors CHEBI:77115 biolink:biological_role_mixin EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of (S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122). Graph (S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122) inhibitor|(S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122) inhibitors|(S)-tetrahydroprotoberberine N-methyltransferase inhibitor|(S)-tetrahydroprotoberberine N-methyltransferase inhibitors|EC 2.1.1.122 ((S)-tetrahydroprotoberberine N-methyltransferase) inhibitor|EC 2.1.1.122 ((S)-tetrahydroprotoberberine N-methyltransferase) inhibitors|EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitors|EC 2.1.1.122 inhibitor|EC 2.1.1.122 inhibitors|S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase inhibitor|S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase inhibitors|tetrahydroprotoberberine cis-N-methyltransferase inhibitor|tetrahydroprotoberberine cis-N-methyltransferase inhibitors CHEBI:77119 biolink:biological_role_mixin EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of prostaglandin-E2 9-reductase (EC 1.1.1.189). Graph (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 9-oxidoreductase inhibitor|(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 9-oxidoreductase inhibitors|9-keto-prostaglandin E2 reductase inhibitor|9-keto-prostaglandin E2 reductase inhibitors|9-ketoprostaglandin reductase inhibitor|9-ketoprostaglandin reductase inhibitors|EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitors|EC 1.1.1.189 inhibitor|EC 1.1.1.189 inhibitors|PGE-9-ketoreductase inhibitor|PGE-9-ketoreductase inhibitors|PGE2 9-oxoreductase inhibitor|PGE2 9-oxoreductase inhibitors|PGE2-9-OR inhibitor|PGE2-9-OR inhibitors|PGE2-9-ketoreductase inhibitor|PGE2-9-ketoreductase inhibitors|prostaglandin 9-ketoreductase inhibitor|prostaglandin 9-ketoreductase inhibitors|prostaglandin E 9-ketoreductase inhibitor|prostaglandin E 9-ketoreductase inhibitors|prostaglandin E2-9-oxoreductase inhibitor|prostaglandin E2-9-oxoreductase inhibitors|prostaglandin-E2 9-reductase (EC 1.1.1.189) inhibitor|prostaglandin-E2 9-reductase (EC 1.1.1.189) inhibitors|reductase, 15-hydroxy-9-oxoprostaglandin inhibitor|reductase, 15-hydroxy-9-oxoprostaglandin inhibitors CHEBI:77182 biolink:biological_role_mixin food colouring A food additive that imparts colour to food. In European countries, E-numbers for permitted food colours are from E 100 to E 199, divided into yellows (E 100-109), oranges (E 110-119), reds (E 120-129), blues and violets (E 130-139), greens (E 140-149), browns and blacks (E 150-159), and others (E 160-199). Graph food coloring|food colorings|food colourings CHEBI:77194 biolink:biological_role_mixin EC 2.7.1.33 (pantothenate kinase) inhibitor An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of pantothenate kinase (EC 2.7.1.33). Graph ATP:(R)-pantothenate 4'-phosphotransferase inhibitor|ATP:(R)-pantothenate 4'-phosphotransferase inhibitors|ATP:pantothenate 4'-phosphotransferase inhibitor|ATP:pantothenate 4'-phosphotransferase inhibitors|D-pantothenate kinase inhibitor|D-pantothenate kinase inhibitors|EC 2.7.1.33 (pantothenate kinase) inhibitors|EC 2.7.1.33 inhibitor|EC 2.7.1.33 inhibitors|pantothenate kinase (EC 2.7.1.33) inhibitor|pantothenate kinase (EC 2.7.1.33) inhibitors|pantothenate kinase (phosphorylating) inhibitor|pantothenate kinase (phosphorylating) inhibitors|pantothenic acid kinase inhibitor|pantothenic acid kinase inhibitors CHEBI:77255 biolink:biological_role_mixin EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of anthrax lethal factor endopeptidase (EC 3.4.24.83). Graph EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitors|EC 3.4.24.83 inhibitor|EC 3.4.24.83 inhibitors|anthrax lethal factor endopeptidase (EC 3.4.24.83) inhibitor|anthrax lethal factor endopeptidase (EC 3.4.24.83) inhibitors|lethal toxin inhibitor|lethal toxin inhibitors CHEBI:77318 biolink:biological_role_mixin pregnane X receptor agonist An agonist that selectively binds to and activates a pregnane X receptor. Graph PXR agonist|PXR agonists|pregnane X receptor agonists CHEBI:77402 biolink:biological_role_mixin EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of trypanothione-disulfide reductase (EC 1.8.1.12). Graph EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitors|EC 1.8.1.12 inhibitor|EC 1.8.1.12 inhibitors|N(1),N(8)-bis(glutathionyl)spermidine reductase inhibitor|N(1),N(8)-bis(glutathionyl)spermidine reductase inhibitors|NADPH2:trypanothione oxidoreductase inhibitor|NADPH2:trypanothione oxidoreductase inhibitors|NADPH:trypanothione oxidoreductase inhibitor|NADPH:trypanothione oxidoreductase inhibitors|trypanothione reductase inhibitor|trypanothione reductase inhibitors|trypanothione-disulfide reductase (EC 1.8.1.12) inhibitor|trypanothione-disulfide reductase (EC 1.8.1.12) inhibitors|trypanothione:NADP(+) oxidoreductase inhibitor|trypanothione:NADP(+) oxidoreductase inhibitors CHEBI:77425 biolink:biological_role_mixin EC 1.1.1.188 (prostaglandin-F synthase) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of prostaglandin-F synthase (EC 1.1.1.188). Graph (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 11-oxidoreductase inhibitor|(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 11-oxidoreductase inhibitors|EC 1.1.1.188 (prostaglandin-F synthase) inhibitors|EC 1.1.1.188 inhibitor|EC 1.1.1.188 inhibitors|NADPH-dependent prostaglandin D2 11-keto reductase inhibitor|NADPH-dependent prostaglandin D2 11-keto reductase inhibitors|PGD2 11-ketoreductase inhibitor|PGD2 11-ketoreductase inhibitors|PGF synthetase inhibitor|PGF synthetase inhibitors|PGF2alpha synthetase inhibitor|PGF2alpha synthetase inhibitors|prostaglandin 11-keto reductase inhibitor|prostaglandin 11-keto reductase inhibitors|prostaglandin 11-ketoreductase inhibitor|prostaglandin 11-ketoreductase inhibitors|prostaglandin D2-ketoreductase inhibitor|prostaglandin D2-ketoreductase inhibitors|prostaglandin F synthase inhibitor|prostaglandin F synthase inhibitors|prostaglandin F synthetase inhibitor|prostaglandin F synthetase inhibitors|prostaglandin-D2 11-reductase inhibitor|prostaglandin-D2 11-reductase inhibitors|reductase, 15-hydroxy-11-oxoprostaglandin inhibitor|reductase, 15-hydroxy-11-oxoprostaglandin inhibitors|synthetase, prostaglandin F2alpha inhibitor|synthetase, prostaglandin F2alpha inhibitors CHEBI:77484 biolink:biological_role_mixin EC 1.1.1.25 (shikimate dehydrogenase) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of shikimate dehydrogenase (EC 1.1.1.25). Graph 5-dehydroshikimate reductase inhibitor|5-dehydroshikimate reductase inhibitors|5-dehydroshikimic reductase inhibitor|5-dehydroshikimic reductase inhibitors|AroE inhibitor|AroE inhibitors|DHS reductase inhibitor|DHS reductase inhibitors|EC 1.1.1.25 (shikimate dehydrogenase) inhibitors|EC 1.1.1.25 inhibitor|EC 1.1.1.25 inhibitors|dehydroshikimic reductase inhibitor|dehydroshikimic reductase inhibitors|shikimate 5-dehydrogenase inhibitor|shikimate 5-dehydrogenase inhibitors|shikimate dehydrogenase (EC 1.1.1.25) inhibitor|shikimate dehydrogenase (EC 1.1.1.25) inhibitors|shikimate dehydrogenase inhibitor|shikimate dehydrogenase inhibitors|shikimate oxidoreductase inhibitor|shikimate oxidoreductase inhibitors|shikimate:NADP(+) 3-oxidoreductase inhibitor|shikimate:NADP(+) 3-oxidoreductase inhibitors|shikimate:NADP(+) 5-oxidoreductase inhibitor|shikimate:NADP(+) 5-oxidoreductase inhibitors|shikimate:NADP(+) oxidoreductase inhibitor|shikimate:NADP(+) oxidoreductase inhibitors CHEBI:77703 biolink:biological_role_mixin EC 4.3.1.3 (histidine ammonia-lyase) inhibitor An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of histidine ammonia-lyase (EC 4.3.1.3). Graph EC 4.3.1.3 (histidine ammonia-lyase) inhibitors|EC 4.3.1.3 inhibitor|EC 4.3.1.3 inhibitors|L-histidine ammonia-lyase (urocanate-forming) inhibitor|L-histidine ammonia-lyase (urocanate-forming) inhibitors|L-histidine ammonia-lyase inhibitor|L-histidine ammonia-lyase inhibitors|histidase inhibitor|histidase inhibitors|histidinase inhibitor|histidinase inhibitors|histidine alpha-deaminase inhibitor|histidine alpha-deaminase inhibitors|histidine ammonia-lyase (EC 4.3.1.3) inhibitor|histidine ammonia-lyase (EC 4.3.1.3) inhibitors|histidine ammonia-lyase inhibitor|histidine ammonia-lyase inhibitors CHEBI:77745 biolink:biological_role_mixin EC 3.4.24.18 (meprin A) inhibitor An EC 3.4.24.* (metalloendopeptidase) inhibitor that inhibits the action of meprin A (EC 3.4.24.18). Graph EC 3.4.24.18 (meprin A) inhibitors|EC 3.4.24.18 inhibitor|EC 3.4.24.18 inhibitors|N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase inhibitor|N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase inhibitors|PABA-peptide hydrolase inhibitor|PABA-peptide hydrolase inhibitors|PPH inhibitor|PPH inhibitors|endopeptidase-2 inhibitor|endopeptidase-2 inhibitors|meprin A (EC 3.4.24.18) inhibitor|meprin A (EC 3.4.24.18) inhibitors|meprin A inhibitor|meprin A inhibitors|meprin inhibitor|meprin inhibitors|meprin-a inhibitor|meprin-a inhibitors CHEBI:77746 biolink:is_metabolite_of human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). Graph H. sapiens metabolite|H. sapiens metabolites|Homo sapiens metabolite|Homo sapiens metabolites CHEBI:77747 biolink:biological_role_mixin EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitor An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of phospholipid-translocating ATPase (EC 3.6.3.1). Graph ATP phosphohydrolase (phospholipid-flipping) inhibitor|ATP phosphohydrolase (phospholipid-flipping) inhibitors|EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitors|EC 3.6.3.1 inhibitor|EC 3.6.3.1 inhibitors|Mg(2)(+)-ATPase inhibitor|Mg(2)(+)-ATPase inhibitors|aminophospholipid-transporting ATPase inhibitor|aminophospholipid-transporting ATPase inhibitors|flippase inhibitor|flippase inhibitors|magnesium-ATPase inhibitor|magnesium-ATPase inhibitors|phospholipid-translocating ATPase (EC 3.6.3.1) inhibitor|phospholipid-translocating ATPase (EC 3.6.3.1) inhibitors|phospholipid-translocating ATPase inhibitor|phospholipid-translocating ATPase inhibitors|phospholipid-transporting ATPase inhibitor|phospholipid-transporting ATPase inhibitors CHEBI:77748 biolink:biological_role_mixin EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of xenobiotic-transporting ATPase (EC 3.6.3.44). Graph ATP phosphohydrolase (steroid-exporting) inhibitor|ATP phosphohydrolase (steroid-exporting) inhibitors|ATP phosphohydrolase (xenobiotic-exporting) inhibitor|ATP phosphohydrolase (xenobiotic-exporting) inhibitors|EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitors|EC 3.6.3.44 inhibitor|EC 3.6.3.44 inhibitors|MDR protein inhibitor|MDR protein inhibitors|P-glycoprotein inhibitor|P-glycoprotein inhibitors|PDR protein inhibitor|PDR protein inhibitors|multidrug-resistance protein inhibitor|multidrug-resistance protein inhibitors|pleiotropic-drug-resistance protein inhibitor|pleiotropic-drug-resistance protein inhibitors|steroid-transporting ATPase inhibitor|steroid-transporting ATPase inhibitors|xenobiotic-transporting ATPase (EC 3.6.3.44) inhibitor|xenobiotic-transporting ATPase (EC 3.6.3.44) inhibitors|xenobiotic-transporting ATPase inhibitor|xenobiotic-transporting ATPase inhibitors CHEBI:77781 biolink:biological_role_mixin EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of 13-deoxydaunorubicin hydroxylase (EC 1.14.13.181). Graph 13-deoxydaunorubicin hydroxylase (EC 1.14.13.181) inhibitor|13-deoxydaunorubicin hydroxylase (EC 1.14.13.181) inhibitors|13-deoxydaunorubicin hydroxylase inhibitor|13-deoxydaunorubicin hydroxylase inhibitors|13-deoxydaunorubicin,NADPH:oxygen oxidoreductase (13-hydroxylating) inhibitor|13-deoxydaunorubicin,NADPH:oxygen oxidoreductase (13-hydroxylating) inhibitors|DoxA inhibitor|DoxA inhibitors|EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitors|EC 1.14.13.181 inhibitor|EC 1.14.13.181 inhibitors CHEBI:77853 biolink:chemical_role_mixin persistent organic pollutant Any environmental contaminant that is resistant to environmental degradation through photolytic, biological or chemical processes. Such substances can have significant impact on health and the environment, as they persist in the environment, bioaccumulate in animal tissue and so biomagnify in food chains. Graph POP|POPs|persistent organic pollutants CHEBI:77881 biolink:biological_role_mixin EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of diaminopropionate ammonia-lyase (EC 4.3.1.15). Graph 2,3-diaminopropanoate ammonia-lyase (adding H2O; pyruvate-forming) inhibitor|2,3-diaminopropanoate ammonia-lyase (adding H2O; pyruvate-forming) inhibitors|2,3-diaminopropanoate ammonia-lyase (adding water; pyruvate-forming) inhibitor|2,3-diaminopropanoate ammonia-lyase (adding water; pyruvate-forming) inhibitors|2,3-diaminopropanoate ammonia-lyase inhibitor|2,3-diaminopropanoate ammonia-lyase inhibitors|2,3-diaminopropionate ammonia-lyase inhibitor|2,3-diaminopropionate ammonia-lyase inhibitors|EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitors|EC 4.3.1.15 inhibitor|EC 4.3.1.15 inhibitors|alpha,beta-diaminopropionate ammonia-lyase inhibitor|alpha,beta-diaminopropionate ammonia-lyase inhibitors|diaminopropionatase inhibitor|diaminopropionatase inhibitors|diaminopropionate ammonia-lyase (EC 4.3.1.15) inhibitor|diaminopropionate ammonia-lyase (EC 4.3.1.15) inhibitors|diaminopropionate ammonia-lyase inhibitor|diaminopropionate ammonia-lyase inhibitors CHEBI:77884 biolink:biological_role_mixin EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of EC 1.14.13.70 (sterol 14alpha-demethylase). Graph EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitors|EC 1.14.13.70 inhibitor|EC 1.14.13.70 inhibitors|cytochrome P450 51 inhibitor|cytochrome P450 51 inhibitors|lanosterol 14-demethylase inhibitor|lanosterol 14-demethylase inhibitors|lanosterol 14alpha-demethylase inhibitor|lanosterol 14alpha-demethylase inhibitors|obtusufoliol 14-demethylase inhibitor|obtusufoliol 14-demethylase inhibitors|sterol 14-demethylase inhibitor|sterol 14-demethylase inhibitors|sterol 14alpha-demethylase inhibitor|sterol 14alpha-demethylase inhibitors|sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving) inhibitor|sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving) inhibitors CHEBI:77941 biolink:biological_role_mixin EC 3.5.1.4 (amidase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4). Graph EC 3.5.1.4 (amidase) inhibitors|EC 3.5.1.4 inhibitor|EC 3.5.1.4 inhibitors|N-acetylaminohydrolase inhibitor|N-acetylaminohydrolase inhibitors|acylamidase inhibitor|acylamidase inhibitors|acylamide amidohydrolase inhibitor|acylamide amidohydrolase inhibitors|amidase (EC 3.5.1.4) inhibitor|amidase (EC 3.5.1.4) inhibitors|amidase inhibitor|amidase inhibitors|amidohydrolase inhibitor|amidohydrolase inhibitors|deaminase inhibitor|deaminase inhibitors|fatty acylamidase inhibitor|fatty acylamidase inhibitors CHEBI:77960 biolink:biological_role_mixin food firming agent A food additive that is used to make or keep fruit or vegetable tissues firm and crisp. or which interacts with gelling agents such as pectin to produce or strengthen a gel. Graph firming agent|firming agents|food firming agents CHEBI:77962 biolink:chemical_role_mixin food antioxidant An antioxidant that used as a food additives to help guard against food deterioration. Graph food antioxidants CHEBI:77969 biolink:biological_role_mixin food humectant A humectant that is used as a food additive to prevent foodstuffs from drying out. Graph food humectants CHEBI:77974 biolink:biological_role_mixin food packaging gas A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container. Graph food packaging gases CHEBI:78017 biolink:biological_role_mixin food propellant A propellant that is used to expel foods from an aerosol container. Graph food propellants CHEBI:78295 biolink:biological_role_mixin food component A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants. Graph dietary component|dietary components|food components CHEBI:78298 biolink:chemical_role_mixin environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Graph environmental contaminants CHEBI:78366 biolink:biological_role_mixin EC 2.7.1.1 (hexokinase) inhibitor An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of hexokinase, EC 2.7.1.1, an enzyme that phosphorylates hexoses forming hexose phosphate. Graph ATP-dependent hexokinase inhibitor|ATP-dependent hexokinase inhibitors|ATP:D-hexose 6-phosphotransferase inhibitor|ATP:D-hexose 6-phosphotransferase inhibitors|EC 2.7.1.1 (hexokinase) inhibitors|EC 2.7.1.1 inhibitor|EC 2.7.1.1 inhibitors|glucose ATP phosphotransferase inhibitor|glucose ATP phosphotransferase inhibitors|hexokinase (phosphorylating) inhibitor|hexokinase (phosphorylating) inhibitors|hexokinase D inhibitor|hexokinase D inhibitors|hexokinase inhibitor|hexokinase inhibitors|hexokinase type I inhibitor|hexokinase type I inhibitors|hexokinase type II inhibitor|hexokinase type II inhibitors|hexokinase type III inhibitor|hexokinase type III inhibitors|hexokinase type IV glucokinase inhibitor|hexokinase type IV glucokinase inhibitors|hexokinase type IV inhibitor|hexokinase type IV inhibitors CHEBI:78377 biolink:biological_role_mixin EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of acyl-CoA dehydrogenase (NADP(+)), EC 1.3.1.8. Graph 2-enoyl-CoA reductase inhibitor|2-enoyl-CoA reductase inhibitors|EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitors|EC 1.3.1.8 inhibitor|EC 1.3.1.8 inhibitors|acyl-CoA dehydrogenase (NADP(+)) (EC 1.3.1.8) inhibitor|acyl-CoA dehydrogenase (NADP(+)) (EC 1.3.1.8) inhibitors|acyl-CoA dehydrogenase (NADP(+)) inhibitor|acyl-CoA dehydrogenase (NADP(+)) inhibitors|acyl-CoA:NADP(+) 2-oxidoreductase inhibitor|acyl-CoA:NADP(+) 2-oxidoreductase inhibitors|crotonyl coenzyme A reductase inhibitor|crotonyl coenzyme A reductase inhibitors|crotonyl-CoA reductase inhibitor|crotonyl-CoA reductase inhibitors|dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate) inhibitor|dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate) inhibitors|enoyl coenzyme A reductase inhibitor|enoyl coenzyme A reductase inhibitors CHEBI:78379 biolink:biological_role_mixin EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7). Graph EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitors|EC 2.5.1.7 inhibitor|EC 2.5.1.7 inhibitors|MurA transferase inhibitor|MurA transferase inhibitors|UDP-N-acetylglucosamine 1-carboxyvinyl-transferase inhibitor|UDP-N-acetylglucosamine 1-carboxyvinyl-transferase inhibitors|UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) inhibitor|UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) inhibitors|UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitor|UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitors|UDP-N-acetylglucosamine enoylpyruvyltransferase inhibitor|UDP-N-acetylglucosamine enoylpyruvyltransferase inhibitors|enoylpyruvate transferase inhibitor|enoylpyruvate transferase inhibitors|phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase inhibitor|phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase inhibitors|phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase inhibitor|phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase inhibitors|phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase inhibitor|phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase inhibitors|phosphoenolpyruvate:UDP-N-acetyl-alpha-D-glucosamine 1-carboxyvinyltransferase inhibitor|phosphoenolpyruvate:UDP-N-acetyl-alpha-D-glucosamine 1-carboxyvinyltransferase inhibitors|phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase inhibitor|phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase inhibitors|phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase inhibitor|phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase inhibitors|phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase inhibitor|phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase inhibitors|pyruvate-UDP-acetylglucosamine transferase inhibitor|pyruvate-UDP-acetylglucosamine transferase inhibitors|pyruvate-uridine diphospho-N-acetyl-glucosamine transferase inhibitor|pyruvate-uridine diphospho-N-acetyl-glucosamine transferase inhibitors|pyruvate-uridine diphospho-N-acetylglucosamine transferase inhibitor|pyruvate-uridine diphospho-N-acetylglucosamine transferase inhibitors|pyruvic-uridine diphospho-N-acetylglucosaminyltransferase inhibitor|pyruvic-uridine diphospho-N-acetylglucosaminyltransferase inhibitors CHEBI:78444 biolink:biological_role_mixin EC 3.1.1.1 (carboxylesterase) inhibitor Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of carboxylesterase (EC 3.1.1.1 ). Graph Alpha-carboxylesterase inhibitor|Alpha-carboxylesterase inhibitors|Beta-esterase inhibitor|Beta-esterase inhibitors|EC 3.1.1.1 (carboxylesterase) inhibitors|ali-esterase inhibitor|ali-esterase inhibitors|butyrate esterase inhibitor|butyrate esterase inhibitors|butyryl esterase inhibitor|butyryl esterase inhibitors|carboxyl ester hydrolase inhibitor|carboxyl ester hydrolase inhibitors|carboxylate esterase inhibitor|carboxylate esterase inhibitors|carboxylesterase inhibitor|carboxylesterase inhibitors|carboxylic acid esterase inhibitor|carboxylic acid esterase inhibitors|carboxylic esterase inhibitor|carboxylic esterase inhibitors|carboxylic-ester hydrolase inhibitor|carboxylic-ester hydrolase inhibitors|cocaine esterase inhibitor|cocaine esterase inhibitors|esterase A inhibitor|esterase A inhibitors|esterase B inhibitor|esterase B inhibitors|esterase D inhibitor|esterase D inhibitors|methylbutyrase inhibitor|methylbutyrase inhibitors|methylbutyrate esterase inhibitor|methylbutyrate esterase inhibitors|monobutyrase inhibitor|monobutyrase inhibitors|nonspecific carboxylesterase inhibitor|nonspecific carboxylesterase inhibitors|procaine esterase inhibitor|procaine esterase inhibitors|propionyl esterase inhibitor|propionyl esterase inhibitors|serine esterase inhibitor|serine esterase inhibitors|triacetin esterase inhibitor|triacetin esterase inhibitors|vitamin A esterase inhibitor|vitamin A esterase inhibitors CHEBI:78675 biolink:is_metabolite_of fundamental metabolite Any metabolite produced by all living cells. Graph essential metabolite|essential metabolites|fundamental metabolites CHEBI:78681 biolink:biological_role_mixin tropomyosin-related kinase B receptor antagonist An antagonist that binds to and deactivates the tropomyosin-related kinase B (TrkB) receptor, the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF). Graph TrkB receptor antagonist|TrkB receptor antagonists|tropomyosin-related kinase B receptor antagonists CHEBI:78691 biolink:biological_role_mixin EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of glycylpeptide N-tetradecanoyltransferase (EC 2.3.1.97). Graph EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitors|myristoyl-CoA-protein N-myristoyltransferase inhibitor|myristoyl-CoA-protein N-myristoyltransferase inhibitors|myristoyl-coenzyme A:protein N-myristoyl transferase inhibitor|myristoyl-coenzyme A:protein N-myristoyl transferase inhibitors|peptide N-myristoyltransferase inhibitor|peptide N-myristoyltransferase inhibitors|protein N-myristoyltransferase inhibitor|protein N-myristoyltransferase inhibitors|tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase inhibitor|tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase inhibitors CHEBI:78763 biolink:biological_role_mixin EC 2.7.11.18 (myosin-light-chain kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of myosin-light-chain kinase (EC 2.7.11.18). Graph ATP:[myosin-light-chain] O-phosphotransferase inhibitor|ATP:[myosin-light-chain] O-phosphotransferase inhibitors|ATP:myosin-light-chain O-phosphotransferase inhibitor|ATP:myosin-light-chain O-phosphotransferase inhibitors|EC 2.7.11.18 (myosin-light-chain kinase) inhibitors|EC 2.7.11.18 inhibitor|EC 2.7.11.18 inhibitors|MLCK inhibitor|MLCK inhibitors|MLCkase inhibitor|MLCkase inhibitors|[myosin-light-chain] kinase inhibitor|[myosin-light-chain] kinase inhibitors|calcium/calmodulin-dependent myosin light chain kinase inhibitor|calcium/calmodulin-dependent myosin light chain kinase inhibitors|myosin kinase inhibitor|myosin kinase inhibitors|myosin light chain kinase inhibitor|myosin light chain kinase inhibitors|myosin light chain protein kinase inhibitor|myosin light chain protein kinase inhibitors|myosin light-chain kinase (phosphorylating) inhibitor|myosin light-chain kinase (phosphorylating) inhibitors|myosin light-chain kinase inhibitor|myosin light-chain kinase inhibitors|myosin-light-chain kinase (EC 2.7.11.18) inhibitor|myosin-light-chain kinase (EC 2.7.11.18) inhibitors|myosin-light-chain kinase inhibitor|myosin-light-chain kinase inhibitors|smooth-muscle-myosin-light-chain kinase inhibitor|smooth-muscle-myosin-light-chain kinase inhibitors CHEBI:78803 biolink:is_metabolite_of nematode metabolite An animal metabolite produced by any member of the phylum Nematoda. Graph nematode metabolites CHEBI:78804 biolink:is_metabolite_of Caenorhabditis elegans metabolite A nematode metabolite produced by Caenorhabditis elegans. Graph C. elegans metabolite|C. elegans metabolites|Caenorhabditis elegans metabolites CHEBI:79091 biolink:biological_role_mixin EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24). Graph ATP:protein phosphotransferase (MAPKK-activated) inhibitor|ATP:protein phosphotransferase (MAPKK-activated) inhibitors|Dp38 inhibitor|Dp38 inhibitors|EC 2.7.11.24 (mitogen-activated protein kinase) inhibitors|EC 2.7.11.24 inhibitor|EC 2.7.11.24 inhibitors|ERK inhibitor|ERK inhibitors|ERK1 inhibitor|ERK1 inhibitors|ERK2 inhibitor|ERK2 inhibitors|JNK inhibitor|JNK inhibitors|JNK3alpha1 inhibitor|JNK3alpha1 inhibitors|LeMPK3 inhibitor|LeMPK3 inhibitors|MAP kinase inhibitor|MAP kinase inhibitors|MAP-2 kinase inhibitor|MAP-2 kinase inhibitors|MAPK inhibitor|MAPK inhibitors|MBP kinase I inhibitor|MBP kinase I inhibitors|MBP kinase II inhibitor|MBP kinase II inhibitors|MEK inhibitor|MEK inhibitors|PMK-1 inhibitor|PMK-1 inhibitors|PMK-2 inhibitor|PMK-2 inhibitors|PMK-3 inhibitor|PMK-3 inhibitors|SAPK inhibitor|SAPK inhibitors|STK26 inhibitor|STK26 inhibitors|c-Jun N-terminal kinase inhibitor|c-Jun N-terminal kinase inhibitors|extracellular signal-regulated kinase inhibitor|extracellular signal-regulated kinase inhibitors|microtubule-associated protein 2 kinase inhibitor|microtubule-associated protein 2 kinase inhibitors|microtubule-associated protein kinase inhibitor|microtubule-associated protein kinase inhibitors|mitogen-activated protein kinase (EC 2.7.11.24) inhibitor|mitogen-activated protein kinase (EC 2.7.11.24) inhibitors|mitogen-activated protein kinase inhibitor|mitogen-activated protein kinase inhibitors|myelin basic protein kinase inhibitor|myelin basic protein kinase inhibitors|p38-2 inhibitor|p38-2 inhibitors|p38delta inhibitor|p38delta inhibitors|p42 mitogen-activated protein kinase inhibitor|p42 mitogen-activated protein kinase inhibitors|p42(mapk) inhibitor|p42(mapk) inhibitors|p44mpk inhibitor|p44mpk inhibitors|pp42 inhibitor|pp42 inhibitors|pp44(mapk) inhibitor|pp44(mapk) inhibitors|stress-activated protein kinase inhibitor|stress-activated protein kinase inhibitors CHEBI:79092 biolink:biological_role_mixin EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any such enzyme using H2O2 as acceptor and incorporating one oxygen atom of the H2O2 into the product (EC 1.11.2.*). Graph EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitors|EC 1.11.2.* inhibitor|EC 1.11.2.* inhibitors CHEBI:79093 biolink:biological_role_mixin EC 1.11.2.2 (myeloperoxidase) inhibitor An EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor that interferes with the action of myeloperoxidase (EC 1.11.2.2). Graph EC 1.11.2.2 (myeloperoxidase) inhibitors|EC 1.11.2.2 inhibitor|EC 1.11.2.2 inhibitors|MPO inhibitor|MPO inhibitors|chloride:hydrogen-peroxide oxidoreductase (hypochlorite-forming) inhibitor|chloride:hydrogen-peroxide oxidoreductase (hypochlorite-forming) inhibitors|myeloperoxidase (EC 1.11.2.2) inhibitor|myeloperoxidase (EC 1.11.2.2) inhibitors|myeloperoxidase inhibitor|myeloperoxidase inhibitors|verdoperoxidase inhibitor|verdoperoxidase inhibitors CHEBI:79386 biolink:biological_role_mixin glycerophosphoinositol synthesis inhibitor A pathway inhibitor that disrupts the synthesis of glycerophosphoinositol Graph GPI synthesis inhibitor|GPI synthesis inhibitors|glycerophosphoinositol synthesis inhibitors CHEBI:82891 biolink:biological_role_mixin glucocorticoid receptor antagonist An antagonist that binds to and deactivates glucocorticoid receptors. Graph glucocorticoid receptor antagonists CHEBI:83038 biolink:is_metabolite_of Daphnia galeata metabolite A Daphnia metabolite produced by the species Daphnia galeata. Graph Daphnia galeata metabolites CHEBI:83039 biolink:is_metabolite_of crustacean metabolite An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill. Graph crustacean metabolites CHEBI:83056 biolink:is_metabolite_of Daphnia magna metabolite A Daphnia metabolite produced by the species Daphnia magna. Graph Daphnia magna metabolites CHEBI:83057 biolink:is_metabolite_of Daphnia metabolite A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia Graph Daphnia metabolites CHEBI:83072 biolink:biological_role_mixin EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor An EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor that interferes with the action of succinate dehydrogenase (quinone), EC 1.3.5.1. Graph EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitors|EC 1.3.5.1 inhibitor|EC 1.3.5.1 inhibitors|SDH inhibitor|SDH inhibitors|complex II inhibitor|complex II inhibitors|succinate dehydrogenase (ubiquinone) inhibitor|succinate dehydrogenase (ubiquinone) inhibitors|succinate dehydrogenase complex inhibitor|succinate dehydrogenase complex inhibitors|succinate dehydrogenase inhibitor|succinate dehydrogenase inhibitors|succinate:quinone oxidoreductase inhibitor|succinate:quinone oxidoreductase inhibitors|succinate:ubiquinone oxidoreductase inhibitor|succinate:ubiquinone oxidoreductase inhibitors|succinic dehydrogenase inhibitor|succinic dehydrogenase inhibitors CHEBI:83146 biolink:is_metabolite_of Daphnia tenebrosa metabolite A Daphnia metabolite produced by the species Daphnia tenebrosa. Graph Daphnia tenebrosa metabolites CHEBI:83316 biolink:biological_role_mixin EC 1.14.13.72 (methylsterol monooxygenase) inhibitor An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of methylsterol monooxygenase (EC 1.14.13.72). Graph 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating) inhibitor|4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating) inhibitors|4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating) inhibitor|4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating) inhibitors|4-methylsterol oxidase inhibitor|4-methylsterol oxidase inhibitors|EC 1.14.13.72 (ethylsterol monooxygenase) inhibitors|EC 1.14.13.72 inhibitor|EC 1.14.13.72 inhibitors|methylsterol hydroxylase inhibitor|methylsterol hydroxylase inhibitors|methylsterol monooxygenase (EC 1.14.13.72) inhibitor|methylsterol monooxygenase (EC 1.14.13.72) inhibitors|methylsterol monooxygenase inhibitor|methylsterol monooxygenase inhibitors CHEBI:83317 biolink:biological_role_mixin sterol biosynthesis inhibitor Any compound that inhibits the biosynthesis of any sterol. Graph sterol biosynthesis inhibitors CHEBI:83319 biolink:biological_role_mixin EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of Delta(14)-sterol reductase (EC 1.3.1.70). Graph 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP(+) Delta(14)-oxidoreductase inhibitor|4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP(+) Delta(14)-oxidoreductase inhibitors|C-14 sterol reductase inhibitor|C-14 sterol reductase inhibitors|Delta(14)-sterol reductase (EC 1.3.1.70) inhibitor|Delta(14)-sterol reductase (EC 1.3.1.70) inhibitors|Delta(14)-sterol reductase inhibitor|Delta(14)-sterol reductase inhibitors|EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitors|EC 1.3.1.70 inhibitor|EC 1.3.1.70 inhibitors|sterol C14-reductase inhibitor|sterol C14-reductase inhibitors CHEBI:83399 biolink:is_metabolite_of marine xenobiotic metabolite Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms. Graph marine xenobiotic metabolites CHEBI:83734 biolink:biological_role_mixin sterol demethylation inhibitor A sterol biosynthesis inhibitor that acts by inhibiting the C14 demethylation step within fungal steroid biosynthesis. Graph sterol demethylation inhibitors CHEBI:84087 biolink:is_metabolite_of human urinary metabolite Any metabolite (endogenous or exogenous) found in human urine samples. Graph human urinary metabolites CHEBI:84264 biolink:biological_role_mixin EC 3.5.1.19 (nicotinamidase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of nicotinamidase (EC 3.5.1.19). Graph EC 3.5.1.19 (nicotinamidase) inhibitors|EC 3.5.1.19 inhibitor|EC 3.5.1.19 inhibitors|YNDase inhibitor|YNDase inhibitors|nicotinamidase (EC 3.5.1.19) inhibitor|nicotinamidase (EC 3.5.1.19) inhibitors|nicotinamidase inhibitor|nicotinamidase inhibitors|nicotinamide amidase inhibitor|nicotinamide amidase inhibitors|nicotinamide amidohydrolase inhibitor|nicotinamide amidohydrolase inhibitors|nicotinamide deaminase inhibitor|nicotinamide deaminase inhibitors CHEBI:84735 biolink:is_metabolite_of algal metabolite Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae. Graph algal metabolites CHEBI:85094 biolink:biological_role_mixin EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cAMP-dependent protein kinase (EC 2.7.11.11). Graph ATP:protein phosphotransferase (cAMP-dependent) inhibitor|ATP:protein phosphotransferase (cAMP-dependent) inhibitors|EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitors|EC 2.7.11.11 inhibitor|EC 2.7.11.11 inhibitors|PKA C inhibitor|PKA C inhibitors|PKA inhibitor|PKA inhibitors|STK22 inhibitor inhibitor|STK22 inhibitors inhibitors|cAMP-dependent protein kinase (EC 2.7.11.11) inhibitor|cAMP-dependent protein kinase (EC 2.7.11.11) inhibitors|cAMP-dependent protein kinase inhibitor|cAMP-dependent protein kinase inhibitors|protein kinase A inhibitor|protein kinase A inhibitors CHEBI:85113 biolink:biological_role_mixin EC 2.7.11.12 (cGMP-dependent protein kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cGMP-dependent protein kinase (EC 2.7.11.12). Graph 3':5'-cyclic GMP-dependent protein kinase inhibitor|3':5'-cyclic GMP-dependent protein kinase inhibitors|ATP:protein phosphotransferase (cGMP-dependent) inhibitor|ATP:protein phosphotransferase (cGMP-dependent) inhibitors|EC 2.7.11.12 (cGMP-dependent protein kinase) inhibitors|EC 2.7.11.12 inhibitor|EC 2.7.11.12 inhibitors|PKG 1alpha inhibitor|PKG 1alpha inhibitors|PKG 1beta inhibitor|PKG 1beta inhibitors|PKG II inhibitor|PKG II inhibitors|PKG inhibitor|PKG inhibitors|STK23 inhibitor|STK23 inhibitors|cGMP-dependent protein kinase (EC 2.7.11.12) inhibitor|cGMP-dependent protein kinase (EC 2.7.11.12) inhibitors|cGMP-dependent protein kinase Ibeta inhibitor|cGMP-dependent protein kinase Ibeta inhibitors|cGMP-dependent protein kinase inhibitor|cGMP-dependent protein kinase inhibitors|guanosine 3':5'-cyclic monophosphate-dependent protein kinase inhibitor|guanosine 3':5'-cyclic monophosphate-dependent protein kinase inhibitors CHEBI:85234 biolink:is_metabolite_of human blood serum metabolite Any metabolite (endogenous or exogenous) found in human blood serum samples. Graph human blood serum metabolites CHEBI:85425 biolink:biological_role_mixin glycine transporter inhibitor Any substance that inhibits the action of glycine transporters. Graph glycine transporter inhibitors CHEBI:85618 biolink:biological_role_mixin EC 2.5.1.31 {ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]} inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]. Graph (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 8 isopentenyl units) inhibitor|(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 8 isopentenyl units) inhibitors|EC 2.5.1.31 inhibitor|EC 2.5.1.31 inhibitors|EC 2.5.1.31 {ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]} inhibitors|UPP synthetase inhibitor|UPP synthetase inhibitors|bactoprenyl-diphosphate synthase inhibitor|bactoprenyl-diphosphate synthase inhibitors|ditrans,polycis-undecaprenyl-diphosphate synthase inhibitor|ditrans,polycis-undecaprenyl-diphosphate synthase inhibitors|ditrans,polycis-undecaprenylcistransferase inhibitor|ditrans,polycis-undecaprenylcistransferase inhibitors|undecaprenyl diphosphate synthetase inhibitor|undecaprenyl diphosphate synthetase inhibitors|undecaprenyl pyrophosphate synthase inhibitor|undecaprenyl pyrophosphate synthase inhibitors|undecaprenyl pyrophosphate synthetase inhibitor|undecaprenyl pyrophosphate synthetase inhibitors|undecaprenyl-diphosphate synthase inhibitor|undecaprenyl-diphosphate synthase inhibitors CHEBI:86264 biolink:is_metabolite_of rat metabolite Any mammalian metabolite produced during a metabolic reaction in rat (Rattus norvegicus). Graph Rattus norvegicus metabolite|Rattus norvegicus metabolites|rat metabolites CHEBI:86327 biolink:biological_role_mixin antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. Graph anti-fungal drug|anti-fungal drugs|anti-fungal medication|anti-fungal medications|antifungal drugs|antifungal medication|antifungal medications|pharmaceutical fungicide|pharmaceutical fungicides CHEBI:86328 biolink:biological_role_mixin antifungal agrochemical Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties. Graph agrichemical fungicide|agrichemical fungicides|agrochemical fungicide|agrochemical fungicides|anti-fungal agrichemical|anti-fungal agrichemicals|anti-fungal agrochemical|anti-fungal agrochemicals|antifungal agrichemical|antifungal agrichemicals|antifungal agrochemicals CHEBI:86383 biolink:biological_role_mixin EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor An EC 5.3.* (intramolecular oxidoreductase) inhibitor that inhibits the action of any such enzyme that transposes C=C bonds (EC 5.3.3.*). Graph EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitors|EC 5.3.3.* inhibitor|EC 5.3.3.* inhibitors|intramolecular oxidase transposing C=C bonds inhibitor (EC 5.3.3.*) inhibitor|intramolecular oxidase transposing C=C bonds inhibitor (EC 5.3.3.*) inhibitors CHEBI:86385 biolink:biological_role_mixin EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor An EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor that interferes with the action of a cholestenol Delta-isomerase (EC 5.3.3.5). Graph Delta(7)-cholestenol Delta(7)-Delta(8)-isomerase inhibitor|Delta(7)-cholestenol Delta(7)-Delta(8)-isomerase inhibitors|EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitors|EC 5.3.3.5 inhibitor|EC 5.3.3.5 inhibitors|cholestenol Delta-isomerase (EC 5.3.3.5) inhibitor|cholestenol Delta-isomerase (EC 5.3.3.5) inhibitors CHEBI:88188 biolink:biological_role_mixin drug allergen Any drug which causes the onset of an allergic reaction. Graph allergenic drug CHEBI:88227 biolink:biological_role_mixin potassium ionophore Any ionophore capable of transportation of potassium ions across membranes. Graph potassium ionophores CHEBI:88230 biolink:biological_role_mixin autophagy inhibitor Any compound that inhibits the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell). Graph autophagocytosis inhibitor|autophagocytosis inhibitors|autophagy inhibitors CHEBI:90318 biolink:biological_role_mixin EC 6.4.1.1 (pyruvate carboxylase) inhibitor An EC 6.4.1.* (carboxylase) inhibitor that interferes with the action of pyruvate carboxylase (EC 6.4.1.1). Graph EC 6.4.1.1 (pyruvate carboxylase) inhibitors|EC 6.4.1.1 inhibitor|EC 6.4.1.1 inhibitors|pyruvate carboxylase (EC 6.4.1.1) inhibitor|pyruvate carboxylase (EC 6.4.1.1) inhibitors|pyruvate carboxylase inhibitor|pyruvate carboxylase inhibitors|pyruvate:carbon-dioxide ligase (ADP-forming) inhibitor|pyruvate:carbon-dioxide ligase (ADP-forming) inhibitors|pyruvic carboxylase inhibitor|pyruvic carboxylase inhibitors CHEBI:91079 biolink:biological_role_mixin purinergic receptor P2 antagonist An antagonist at purinergic P2 receptors Graph P2 antagonist|P2 antagonists|non-selective P2 purinergic antagonist|non-selective P2 purinergic antagonists|purinergic receptor P2 antagonists CHEBI:91139 biolink:biological_role_mixin elastin-laminin receptor agonist An agonist that selectively binds to and activates elastin-laminin receptors. Graph ELR agonist|ELR agonists|elastin-laminin receptor agonists CHEBI:has_functional_parent biolink:derives_from Graph CHEBI:has_parent_hydride biolink:subclass_of Graph CHEBI:is_conjugate_acid_of biolink:related_to Graph CHEBI:is_conjugate_base_of biolink:related_to Graph CHEBI:is_enantiomer_of biolink:close_match Graph CHEBI:is_substituent_group_from biolink:part_of Graph CHEBI:is_tautomer_of biolink:close_match Graph CL:has_completed biolink:has_completed Graph CL:has_high_plasma_membrane_amount biolink:has_increased_amount Graph CL:has_low_plasma_membrane_amount biolink:has_decreased_amount Graph CL:has_not_completed biolink:has_not_completed Graph CL:lacks_part biolink:lacks_part Graph CL:lacks_plasma_membrane_part biolink:lacks_part Graph DDANAT:develops_from biolink:develops_from Graph ENVO:01001307 biolink:coexists_with Graph EXO:0000000 biolink:has_stressor Graph EXO:0000001 biolink:has_receptor Graph EXO:0000055 biolink:has_route Graph FMA:adheres_to biolink:physically_interacts_with Graph FMA:adjacent_to biolink:coexists_with Graph FMA:afferent_to biolink:coexists_with Graph FMA:anterior_to biolink:coexists_with Graph FMA:anteroinferior_to biolink:coexists_with Graph FMA:anterolateral_to biolink:coexists_with Graph FMA:anteromedial_to biolink:coexists_with Graph FMA:anterosuperior_to biolink:coexists_with Graph FMA:arterial_supply_of biolink:coexists_with Graph FMA:articulates_with biolink:coexists_with Graph FMA:attaches_to biolink:coexists_with Graph FMA:bounded_by biolink:coexists_with Graph FMA:bounds biolink:coexists_with Graph FMA:branch_of biolink:coexists_with Graph FMA:connected_to biolink:related_to Graph FMA:connection_type_of biolink:coexists_with Graph FMA:constitutional_part_of biolink:part_of Graph FMA:continuation_branch_of biolink:coexists_with Graph FMA:continuous_distally_with biolink:coexists_with Graph FMA:continuous_proximally_with biolink:coexists_with Graph FMA:continuous_with biolink:related_to Graph FMA:corresponds_to biolink:coexists_with Graph FMA:derives biolink:derives_into Graph FMA:derives_from biolink:derives_from Graph FMA:development_type_of biolink:coexists_with Graph FMA:developmental_stage_of biolink:coexists_with Graph FMA:develops_from biolink:develops_from Graph FMA:direct_cell_shape_of biolink:coexists_with Graph FMA:direct_left_of biolink:coexists_with Graph FMA:direct_right_of biolink:coexists_with Graph FMA:distal_to biolink:coexists_with Graph FMA:drains_into biolink:coexists_with Graph FMA:efferent_to biolink:coexists_with Graph FMA:external_to biolink:coexists_with Graph FMA:formed_by biolink:coexists_with Graph FMA:forms biolink:coexists_with Graph FMA:full_grown_phenotype_of biolink:coexists_with Graph FMA:fuses_with biolink:coexists_with Graph FMA:fusion_of biolink:coexists_with Graph FMA:germ_origin_of biolink:coexists_with Graph FMA:has_adherent biolink:coexists_with Graph FMA:has_arterial_supply biolink:coexists_with Graph FMA:has_branch biolink:coexists_with Graph FMA:has_connection_type biolink:coexists_with Graph FMA:has_constitutional_part biolink:has_part Graph FMA:has_continuation_branch biolink:coexists_with Graph FMA:has_development_type biolink:coexists_with Graph FMA:has_developmental_stage biolink:coexists_with Graph FMA:has_direct_cell_shape biolink:coexists_with Graph FMA:has_full_grown_phenotype biolink:coexists_with Graph FMA:has_fusion biolink:coexists_with Graph FMA:has_germ_origin biolink:coexists_with Graph FMA:has_inherent_3d_shape biolink:coexists_with Graph FMA:has_insertion biolink:coexists_with Graph FMA:has_location biolink:located_in Graph FMA:has_lymphatic_drainage biolink:coexists_with Graph FMA:has_member biolink:has_part Graph FMA:has_nerve_supply biolink:coexists_with Graph FMA:has_observed_anatomical_entity biolink:coexists_with Graph FMA:has_origin biolink:coexists_with Graph FMA:has_part biolink:has_part Graph FMA:has_primary_segmental_supply biolink:coexists_with Graph FMA:has_projection biolink:coexists_with Graph FMA:has_regional_part biolink:coexists_with Graph FMA:has_related_developmental_entity biolink:coexists_with Graph FMA:has_secondary_segmental_supply biolink:coexists_with Graph FMA:has_segmental_composition biolink:coexists_with Graph FMA:has_segmental_supply biolink:coexists_with Graph FMA:has_tributary biolink:coexists_with Graph FMA:has_venous_drainage biolink:coexists_with Graph FMA:homonym_of biolink:related_to Graph FMA:inferior_to biolink:coexists_with Graph FMA:inferolateral_to biolink:coexists_with Graph FMA:inferomedial_to biolink:coexists_with Graph FMA:inherent_3d_shape_of biolink:coexists_with Graph FMA:insertion_of biolink:coexists_with Graph FMA:internal_to biolink:coexists_with Graph FMA:lateral_to biolink:coexists_with Graph FMA:left_lateral_to biolink:coexists_with Graph FMA:left_medial_to biolink:coexists_with Graph FMA:location_of biolink:location_of Graph FMA:lymphatic_drainage_of biolink:coexists_with Graph FMA:matures_from biolink:coexists_with Graph FMA:matures_into biolink:coexists_with Graph FMA:medial_to biolink:coexists_with Graph FMA:member_of biolink:part_of Graph FMA:merges_with biolink:coexists_with Graph FMA:nerve_supply_of biolink:coexists_with Graph FMA:origin_of biolink:coexists_with Graph FMA:part_of biolink:part_of Graph FMA:posterior_to biolink:coexists_with Graph FMA:posteroinferior_to biolink:coexists_with Graph FMA:posterolateral_to biolink:coexists_with Graph FMA:posteromedial_to biolink:coexists_with Graph FMA:posterosuperior_to biolink:coexists_with Graph FMA:primary_segmental_supply_of biolink:coexists_with Graph FMA:projects_from biolink:coexists_with Graph FMA:projects_to biolink:coexists_with Graph FMA:proximal_to biolink:coexists_with Graph FMA:receives_attachment_from biolink:coexists_with Graph FMA:receives_drainage_from biolink:coexists_with Graph FMA:receives_input_from biolink:coexists_with Graph FMA:receives_projection biolink:coexists_with Graph FMA:regional_part_of biolink:part_of Graph FMA:related_developmental_entity_of biolink:related_to Graph FMA:related_part biolink:coexists_with Graph FMA:right_lateral_to biolink:coexists_with Graph FMA:right_medial_to biolink:coexists_with Graph FMA:secondary_segmental_supply_of biolink:coexists_with Graph FMA:segmental_composition_of biolink:coexists_with Graph FMA:segmental_supply_of biolink:coexists_with Graph FMA:sends_output_to biolink:coexists_with Graph FMA:superior_to biolink:coexists_with Graph FMA:superolateral_to biolink:coexists_with Graph FMA:superomedial_to biolink:coexists_with Graph FMA:surrounded_by biolink:coexists_with Graph FMA:surrounds biolink:coexists_with Graph FMA:transforms_from biolink:preceded_by Graph FMA:transforms_into biolink:precedes Graph FMA:tributary_of biolink:coexists_with Graph FMA:venous_drainage_of biolink:coexists_with Graph FOODON:00001301 biolink:model_of Graph FOODON:00001563 biolink:has_part Graph FOODON:00002420 biolink:has_part Graph GENO:0000382 biolink:has_variant_part Graph GENO:0000790 biolink:related_condition Graph GENO:0000897 biolink:GenomicEntity Graph GENO:0000907 biolink:GeneProductMixin Graph GOREL:0000040 biolink:causes Graph GOREL:0001004 biolink:located_in Graph GOREL:0001006 biolink:affects Graph GOREL:0002005 biolink:related_to Graph GOREL:0012006 biolink:related_to Graph GO:inverse_isa biolink:superclass_of Graph GO:isa biolink:subclass_of Graph IAO:0000039 biolink:has_unit has measurement unit label Graph IAO:0000136 biolink:synonym is about is_about is a (currently) primitive relation that relates an information artifact to an entity. Graph IAO:0000142 biolink:mentions Graph INO:0000154 biolink:has_attribute Graph MI:1046 biolink:interacting_molecules_category Graph MI:2044 biolink:mechanism_of_action Graph MONDO:disease_causes_feature biolink:causes Graph MONDO:disease_has_basis_in_accumulation_of biolink:disease_has_basis_in Graph MONDO:disease_has_basis_in_development_of biolink:disease_has_basis_in Graph MONDO:disease_has_location biolink:disease_has_location Graph MONDO:disease_has_major_feature biolink:has_part Graph MONDO:disease_responds_to biolink:treated_by Graph MONDO:disease_shares_features_of biolink:related_to Graph MONDO:disease_triggers biolink:causes Graph MONDO:equivalentTo biolink:same_as Graph MONDO:part_of_progression_of_disease biolink:part_of Graph MONDO:predisposes_towards biolink:contributes_to Graph MPATH:0 biolink:PathologicalEntityMixin pathological entity Pathological structure or process Graph MPATH:1 biolink:PathologicalEntityMixin cell and tissue damage The sum of morphological and functional disturbances induced by cell and tissue damage, either from intrinsic gene dysfunction or as a result of external factors. Graph MPATH:100 biolink:PathologicalEntityMixin placental abnormality Defect in placental growth, differentiation of circulation; maternal or embryonic component. Graph MPATH:101 biolink:PathologicalEntityMixin glycogen cell defect Lack of, displacement of, or abnormality in function or growth of the glycogen cells. Graph MPATH:102 biolink:PathologicalEntityMixin labyrinth zone defect Defect in size, cellular composition, function or organisation of the labyrinthine zone of the placenta. Graph MPATH:103 biolink:PathologicalEntityMixin placental vascular defect Any defect in the maternal or embryonic placental circulation. Graph MPATH:104 biolink:PathologicalEntityMixin spongiotrophoblast defect Defect in size, cellular composition, function or organisation of the spongiotrophoblast zone of the placenta. Graph MPATH:105 biolink:PathologicalEntityMixin circulatory disorder Lesions leading to or consequent on failure of, or atypical movement of, blood throughout the body. Graph MPATH:106 biolink:PathologicalEntityMixin fluid accumulation Abnormal accumulation of fluid; blood or lymph. Graph MPATH:107 biolink:PathologicalEntityMixin congestion Presence of an abnormal amount of fluid (but especially of blood) in the vessels or passages of a part or organ. Graph MPATH:108 biolink:PathologicalEntityMixin disseminated intravascular coagulation A syndrome consequent to uncontrolled activation of blood clotting factors leading to disseminated platelet lysis, and fibrin deposition, ultimately leading to bleeding and necrosis as a consequence of inhibition of fibrin polymerisation by degradation products. Graph DIC MPATH:109 biolink:PathologicalEntityMixin edema An accumulation of an excessive amount of watery fluid in cells or intercellular tissues. Graph oedema MPATH:110 biolink:PathologicalEntityMixin embolus A plug formed from a variety of materials occluding a vessel or tube. Graph MPATH:111 biolink:PathologicalEntityMixin air embolism An bubble of air occluding flow through a blood or lymphatic vessel. Graph MPATH:112 biolink:PathologicalEntityMixin amniotic fluid embolism Occlusion of vessels caused by entry of amniotic fluid, cell and debris into the maternal circulation. Graph MPATH:113 biolink:PathologicalEntityMixin atrial embolism Occlusion of the outflow tract of the right atrium by a thrombus. Graph MPATH:114 biolink:PathologicalEntityMixin bone marrow embolism Occlusion of vessels caused by entry of bone marrow, often fatty debris into the circulation. Usually following trauma. Graph MPATH:115 biolink:PathologicalEntityMixin fat embolism Occlusion of vessels caused by entry of lipid or fatty cells into the circulation. Usually following trauma. Graph MPATH:116 biolink:PathologicalEntityMixin pulmonary embolism Occlusion of pulmonary vessels by an embolus. Graph MPATH:117 biolink:PathologicalEntityMixin skin embolism Occlusion of vessels, usually small arterioles in the dermis by various emboli. Graph MPATH:118 biolink:PathologicalEntityMixin systemic embolism Production of systemic vessel occlusion by emboli released from the left side of the heart, or the aorta. Graph MPATH:119 biolink:PathologicalEntityMixin hemorrhage and non-specified extravasation Abnormal release of whole blood or the cellular component from the circulation. Graph MPATH:120 biolink:PathologicalEntityMixin ecchymosis A red/purple patch caused by extravasation of blood into the skin. Larger than petechiae. Graph MPATH:121 biolink:PathologicalEntityMixin hematoma A localised deposition of clotted or partially clotted extravasated blood. Graph Bruise MPATH:122 biolink:PathologicalEntityMixin petechia Small hemorrhagic spots in the skin caused by blood vessel breakdown. Graph MPATH:123 biolink:PathologicalEntityMixin purpura Purple and variously colored lesions caused by extensive haemorrhage into the skin through ecchymoses/petechia. Graph MPATH:124 biolink:PathologicalEntityMixin infarct An area of necrosis resulting from a sudden cessation of arterial or venous blood supply. Graph MPATH:125 biolink:PathologicalEntityMixin thrombosis Presence of an occluding or mural thrombus in a blood vessel. Graph MPATH:126 biolink:PathologicalEntityMixin growth and differentiation defect Defects in growth (changes in proliferation or mass) and differentiation of cells tissues or organs. Graph MPATH:128 biolink:PathologicalEntityMixin intra-epithelial neoplasia Non-invasive changes characterized by alteration in the size, shape and organization of the cellular components of an epithelial tissue. Do not confuse with developmental dysplasia MPATH:64. Graph intra-epithelial lesion MPATH:130 biolink:PathologicalEntityMixin mild intra-epithelial neoplasia Mild non-invasive changes in cell morphology and tissue architecture confined to the epithelium alone. Graph IENI|low grade intraepithelial lesion|mild epithelial dysplasia. MPATH:131 biolink:PathologicalEntityMixin moderate intra-epithelial epithelial neoplasia Moderate non-invasive changes in cell morphology and tissue architecture confined to the epithelium alone. Graph IENII|high grade intraepithelial lesion|moderate epithelial dysplasia MPATH:132 biolink:PathologicalEntityMixin severe intra-epithelial neoplasia Severe non-invasive malignancy associated changes in cell morphology and tissue architecture confined to the epithelium alone. Graph IENIII|carcinoma in situ|high grade intra-epithelial lesion|severe epithelial dysplasia MPATH:135 biolink:PathologicalEntityMixin epithelial and stromal hyperplasia Abnormal proliferation of epithelial and stromal cells. Graph MPATH:136 biolink:PathologicalEntityMixin fibroepithelial polyp A polypoid outgrowth of both epidermis and dermal fibrovascular tissue. Graph skin tag MPATH:137 biolink:PathologicalEntityMixin fibroglandular hyperplasia Benign proliferation of glandular epithelium accompanied by proliferation of fibroblastic stroma. Graph MPATH:138 biolink:PathologicalEntityMixin epithelial hyperplasia Abnormal proliferation of epithelial cells and epithelial components. Graph MPATH:139 biolink:PathologicalEntityMixin goblet cell hyperplasia Benign proliferation of goblet cells. Graph MPATH:140 biolink:PathologicalEntityMixin hyperplastic polyp A benign polyp, usually in the colon, showing hyperplasia. Graph MPATH:141 biolink:PathologicalEntityMixin inflammatory polyp A projecting mass of granulation tissue which may become covered by regenerating epithelium. Graph pseudopolyp MPATH:142 biolink:PathologicalEntityMixin intraductal hyperplasia Benign hyperplasia of the ducts of the mammary gland. Ducts exhibit more than the usual two layer epithelium (inner cuboidal to columnar cells; outer layer of myoepithelium) without cytological atypia. Graph MPATH:143 biolink:PathologicalEntityMixin microglandular hyperplasia Benign proliferation of glandular epithelia, eg. Endocervical glands. Consists of tightly packed glandular or tubular units, which vary in size, lined by a flattened-to-cuboidal epithelium. Graph microglandular adenosis MPATH:144 biolink:PathologicalEntityMixin myoepithelial hyperplasia Benign proliferation of glandular myoepithelial cells. Graph MPATH:145 biolink:PathologicalEntityMixin fat cell hyperplasia Benign proliferation of adipose tissue. Graph MPATH:147 biolink:PathologicalEntityMixin lymphoid hyperplasia Benign enlargement of lymphoid tissues. Graph lymphoid hypertrophy MPATH:148 biolink:PathologicalEntityMixin mesothelial hyperplasia Benign proliferation of mesothelial cells lining body cavities presenting as small solid cell clusters or multiple layers with columnar morphology and delicate eosinophilic cytoplasm. Graph mesothelioma MPATH:149 biolink:PathologicalEntityMixin squamous hyperplasia Benign proliferation of epidermal cells with hyperkeratosis. Variable growth pattern, regular to papillary (exophytic squamous cell hyperplasia). Graph epidermal hyperplasia.|squamous cell hyperplasia MPATH:150 biolink:PathologicalEntityMixin acanthosis Hyperplasia of the Malpighian layer (prickle cell) of the epidermis. Graph MPATH:151 biolink:PathologicalEntityMixin actinic keratosis Discrete, flat or elevated, verrucous, keratotic lesions. Epidermal changes are characterized by acanthosis, parakeratosis, and dyskeratoses. Dysplastic change is present and the keratinocytes vary in size and shape. Associated with UV exposure in humans. Not defined in mice to date. Graph MPATH:152 biolink:PathologicalEntityMixin basal cell hyperplasia Benign proliferation of the basal layer cells of the skin. Graph MPATH:153 biolink:PathologicalEntityMixin hypergranulosis Increased thickness of the granular layer of a stratified squamous epithelium, associated with hyperorthokeratosis. Graph MPATH:154 biolink:PathologicalEntityMixin hyperkeratosis Thickening of the surface layers (stratum corneum) in the skin or other stratified squamous epithelium. Cf. ortho- and para-keratosis. Graph cornification|hyperorthokeratosis|hyperparakeratosis MPATH:155 biolink:PathologicalEntityMixin orthokeratosis Thickening of the anuclear cell layer limited to the stratum corneum, as in a stratified squamous epithelium. Graph MPATH:156 biolink:PathologicalEntityMixin parakeratosis Thickening of the surface cell layer of a stratified squamous epithelium with retention of nuclei in the cells of the stratum corneum. Graph MPATH:157 biolink:PathologicalEntityMixin pseudoepithelioma/pseudocarcinoma Benign hyperplasia and down-growth of epidermal cells. Microscopically resembling well-differentiated squamous cell carcinoma. Graph pseudocarcinoma|pseudocarcinomatous hyperplasia|pseudoepitheliomatous hyperplasia MPATH:158 biolink:PathologicalEntityMixin seborrheic keratosis Superficial, benign, verrucous, often pigmented, greasy lesions consisting of proliferating epidermal cells, resembling basal cells, enclosing cornifying cysts. Graph Basal cell papilloma|seborrheic verruca MPATH:161 biolink:PathologicalEntityMixin cartilaginous metaplasia Metaplasia resulting in heterotopic formation of cartilage. Graph MPATH:162 biolink:PathologicalEntityMixin epithelial metaplasia Metaplasia occurring within epithelia. Graph MPATH:163 biolink:PathologicalEntityMixin apocrine metaplasia Alteration of acinar epithelium of, for example, mammary tissue to resemble apocrine glands. Graph MPATH:164 biolink:PathologicalEntityMixin gastric metaplasia Appearance of heterotopic gastric epithelium. Graph MPATH:165 biolink:PathologicalEntityMixin glandular metaplasia Development of heterotopic glandular epithelia. Graph MPATH:166 biolink:PathologicalEntityMixin goblet cell metaplasia Metaplasia resulting in formation of mucus secreting goblet cells. Graph MPATH:167 biolink:PathologicalEntityMixin intestinal metaplasia Appearance of heterotopic intestinal epithelium. Graph MPATH:168 biolink:PathologicalEntityMixin lipomatous metaplasia Metaplasia resulting in formation of fat cells. Graph MPATH:169 biolink:PathologicalEntityMixin nephrogenic metaplasia .A rare benign neoplasm of the mucosa of the urinary bladder or the urethra, consisting of tubular structures resembling those of the nephron. Graph nephrogenic adenoma MPATH:17 biolink:PathologicalEntityMixin subcellular defect Defect of a subcellular structure or organelle. Graph MPATH:170 biolink:PathologicalEntityMixin oncocytic metaplasia Appearance of oncocytic cells in for example an epithelium or tumor. Graph MPATH:171 biolink:PathologicalEntityMixin squamous metaplasia Change of a glandular or mucosal epithelium into squamous epithelium. Graph MPATH:172 biolink:PathologicalEntityMixin transitional cell metaplasia Metaplastic response of the transitional epithelium, for example in the bladder to give squamous metaplasia and glandular metaplasia for example. Graph MPATH:173 biolink:PathologicalEntityMixin myeloid metaplasia A progressive disease of the bone marrow where neoplastic bone marrow stem cells lodge and grow at sites outside the bone marrow. Graph MPATH:174 biolink:PathologicalEntityMixin osseous metaplasia Metaplasia resulting in formation of bone. Graph ectopic bone MPATH:18 biolink:PathologicalEntityMixin cytoskeletal defect Defect in the structure or function of the cytoskeleton. Graph MPATH:183 biolink:PathologicalEntityMixin granulation tissue Newly formed connective (vascular or fibrous)tissue caused by inflammation or healing (repair) processes. Microscopically consists of capillaries fibroblastic cells and inflammatory cells. Graph MPATH:19 biolink:PathologicalEntityMixin endoplasmic reticulum defect Defect in the structure or function of the endoplasmic reticulum. Graph MPATH:20 biolink:PathologicalEntityMixin golgi defect Defect in the structure or function of the golgi apparatus. Graph MPATH:21 biolink:PathologicalEntityMixin lysosomal defect Defect in the structure or function of the lysosomes. Graph MPATH:218 biolink:PathologicalEntityMixin neoplasm A tumor resulting from abnormal and uncontrolled autonomous new cell growth (proliferation)that may be benign or malignant. Graph MPATH:219 biolink:PathologicalEntityMixin adnexal and skin appendage tumor Tumors of the skin, its constituent structures and glands including the mammary gland, apocrine and eccrine glands, hair follicles and associated structures. Graph MPATH:22 biolink:PathologicalEntityMixin mitochondrial defect Defect in the structure or function of the mitochondria. Graph MPATH:220 biolink:PathologicalEntityMixin apocrine adenocarcinoma Carcinoma of the glandular epithelium of apocrine glands (M-8401/3). Graph MPATH:221 biolink:PathologicalEntityMixin apocrine adenoma Benign neoplasm of the epithelium of apocrine glands (M-8401/0). Graph MPATH:222 biolink:PathologicalEntityMixin ceruminous adenocarcinoma Malignant carcinoma of the ceruminous gland (M-8420/3). Graph MPATH:223 biolink:PathologicalEntityMixin ceruminous adenoma Benign adenomatous neoplasia of the ceruminous glands of the external auditory meatus (M-8420/0). Graph MPATH:224 biolink:PathologicalEntityMixin clear cell hidradenoma Tumor derived from eccrine sweat glands composed of clear glycogen rich cells. ( M-84020 ). Graph Eccrine acrospiroma|nodular hidradenoma MPATH:225 biolink:PathologicalEntityMixin eccrine gland adenocarcinoma Malignant neoplasm of the eccrine gland (M-8413/3). Graph MPATH:226 biolink:PathologicalEntityMixin eccrine gland adenoma Benign neoplasm of the eccrine gland (M-8408/0). Graph MPATH:227 biolink:PathologicalEntityMixin eccrine papillary adenoma Papillary form of eccrine sweat gland adenoma. (M -8408/0). Graph Papillary adenoma|benign neoplasm of the eccrine gland, papillary form MPATH:228 biolink:PathologicalEntityMixin papillary hidradenoma Benign apocrine sweat gland tumor (8405/0). Graph Hidradenoma papilliferum MPATH:229 biolink:PathologicalEntityMixin sebaceous adenocarcinoma Malignant neoplasm of the sebaceous cells - rare areas of differentiation, severe nuclear atypia (M-8410/3). Graph sebaceous carcinoma MPATH:23 biolink:PathologicalEntityMixin peroxysomal defect Defect in the structure or function of the peroxysomes. Graph MPATH:230 biolink:PathologicalEntityMixin sebaceous adenoma Adenoma of sebaceous cells; regular architecture of gland not mantained. Large numbers of immature germinative cells present. Mitoses. (M-8410/0). Graph Epithelioma MPATH:231 biolink:PathologicalEntityMixin syringoma A benign, often multiple, sometimes eruptive neoplasm of the sweat gland ducts composed of very small round cysts. (M-8407/0). Graph MPATH:232 biolink:PathologicalEntityMixin trichoepithelioma Multiple small benign nodules derived from basal cells of hair follicles enclosing small cornified cell containing cysts. (M-8100/0). Graph Epithelioma adenoides cysticum|benign|hair follicle tumor MPATH:233 biolink:PathologicalEntityMixin basal cell tumor Well circumscribed tumor of the basal cells of the epidermis. Rare mitotic figures, benign. (M8147/0). Graph Benign basal cell tumor|basal cell adenoma MPATH:234 biolink:PathologicalEntityMixin basal cell carcinoma Malignant neoplasm of the basal cells of the epidermis with local invasion. (M-8090/3). Graph MPATH:235 biolink:PathologicalEntityMixin blood vessel tumor Tumor of venous or arterial vessels or capillaries. Graph MPATH:236 biolink:PathologicalEntityMixin angiofibroma .A benign neoplasm of fibrous tissue in which there are multiple large and small dilated vascular channels ( M9160/0). Graph Telangiectatic fibroma MPATH:237 biolink:PathologicalEntityMixin angiokeratoma An intradermal capillary telangiectasis with hyperkeratosis and acanthosis (M-9141/0). Graph keratoangioma|telangiectasia verrucosa|telangiectatic wart MPATH:238 biolink:PathologicalEntityMixin hemangioblastoma A benign neoplasm frequently arising in the cerebellum composed of capillary vessel forming endothelial cells and stromal cells. (M-9161/1). Graph Angioblastoma MPATH:24 biolink:PathologicalEntityMixin plasma membrane defect Defect in the structure or function of the plasma membrane. Graph MPATH:240 biolink:PathologicalEntityMixin hemangioma Neoplasm derived from endothelial cells. May be of capillary or cavernous type with large vascular channels. (M-9130/0 + M-9120/0 respectively). Graph Angioendothelioma.|Hemangioendothelioma, benign MPATH:241 biolink:PathologicalEntityMixin hemangiopericytoma A vascular, usually benign, neoplasm composed of round and spindle cells derived from the pericytes and surround endothelium-lined vessels. (M-9150/0/1/3). Graph Pericytoma MPATH:242 biolink:PathologicalEntityMixin hemangiosarcoma Malignant neoplasm derived from pluripotential mesenchymal stem cells or endothelial cells of blood vessels. (M-9120/3). Graph Hemangioma malignant|hemangioendothelioma malignant, angiosarcoma|hemangioendothelioma malignant. MPATH:243 biolink:PathologicalEntityMixin central nervous system tumor Neoplasm of the neurones, glia or meninges of the CNS. Graph MPATH:244 biolink:PathologicalEntityMixin astrocytoma Glioma derived from astrocytes, both benign and malignant forms (M-9400/3). Graph Astrocytic glioma|astroglioma MPATH:245 biolink:PathologicalEntityMixin choroid plexus carcinoma Malignant neoplasm derived from the epithelial cells of the choroid plexus. (M-9390/3). Graph MPATH:246 biolink:PathologicalEntityMixin choroid plexus papilloma Benign neoplasm derived from the epithelial cells of the choroid plexus. (M-9390/0). Graph MPATH:247 biolink:PathologicalEntityMixin ependymoma Neoplasm derived from the ependymal cells lining the ventricles and aqueduct of the brain and the central canal of the spinal cord. Malignant or benign. (M-9391/3). Graph MPATH:249 biolink:PathologicalEntityMixin glioma Neoplasm derived from astrocytes and oligodendrocytes. (M-9380/3, M-9440/3). Graph MPATH:250 biolink:PathologicalEntityMixin medulloblastoma Neoplasm derived from the primitive neurectodermal cells of the cerebellum. (M-9470/3). May be considered by some authorities a synonym of PNET in the CNS. Graph MPATH:251 biolink:PathologicalEntityMixin meningioma meningioma Graph Sarcoma, meningeal ( sensu malignant tumor) MPATH:252 biolink:PathologicalEntityMixin oligodendroglioma Benign or malignant neoplasm derived form oligodendrocytes (M-9450/3). Graph Glioma, oligodendritic, benign|glioma oligodendritic, malignant MPATH:253 biolink:PathologicalEntityMixin sub-ependymoma Neoplasm derived from sub-ependymal astrocytes (M-9383/1). Graph MPATH:254 biolink:PathologicalEntityMixin complex tumor Tumors showing multiple histological componants/differentiation. Graph MPATH:255 biolink:PathologicalEntityMixin adenoacanthoma Mixed tumor of glandular epithelia with squamous and glandular diffferentiation. (M-8570/3). Graph adenoid squamous cell carcinoma MPATH:256 biolink:PathologicalEntityMixin carcinosarcoma Possible origin from smooth muscle cells or pluripotential embryonic mesenchymal cells. May show up to three cellular componants including carcinoma and sarcoma type appearances. (M-8980/3). Graph MPATH:257 biolink:PathologicalEntityMixin craniopharyngioma A benign or malignant neoplasm, which may be cystic, developing from the epithelium of Rathke`s pouch and occuring with or close to the pituitary gland. (M-9350/1). Graph Erdheim tumor|Pituitary adamantinoma|Rathke pouch tumor|pituitary ameloblastoma|suprasellar cyst MPATH:258 biolink:PathologicalEntityMixin mesodermal mixed tumor Neoplasm showing multiple phases, derived from mesoderm (M-8951/3). Graph MPATH:259 biolink:PathologicalEntityMixin mucoepidermoid carcinoma Most commonly a salivary gland carcinoma of low grade malignancy composed of mucous, epidermoid, and intermediate cells. (M-8430/3). Graph MPATH:260 biolink:PathologicalEntityMixin mullerian mixed tumor Neoplasm usually of the uterus or adnexae containing carcinomatous and sarcomatous elements, sometimes with third or fourth components. (M-8950/3). Graph MPATH:261 biolink:PathologicalEntityMixin nephroblastoma Embryonal tumor thought to be derived from metanephric blastema. Mono, bi or triphasic, sometimes with heterotypic differentiation. (M-8960/3). Graph nephroma MPATH:262 biolink:PathologicalEntityMixin pulmonary blastoma A biphasic tumor containing a primitive epithelial component, that may resemble well-differentiated fetal adenocarcinoma and a primitive mesenchymal stroma, which occasionally has foci of osteosarcoma, chondrosarcoma or rhadomyosarcoma. (M-8972/3). Graph MPATH:263 biolink:PathologicalEntityMixin rhabdoid sarcoma Sarcomatous tumors, presenting a wide histological, ultrastructural, and immunocytochemical spectrum. M-8963/3. Graph Malignant rhabdoid tumor MPATH:264 biolink:PathologicalEntityMixin fibroepithelial tumor Tumors with epithelial invaginations/linings and a fibrillary and fibrocytic stroma. (M-9000 - M-9030). Graph MPATH:265 biolink:PathologicalEntityMixin adenofibroma A benign neoplasm composed of glandular and fibrous tissues, predominantly glandular. (M-9013/0). Graph Cystadenofibroma|papillary adenofibroma MPATH:266 biolink:PathologicalEntityMixin fibroadenoma A benign neoplasm derived from glandular epithelium, in which there is a abundant stroma of proliferating fibroblasts and connective tissue. (M-9010/0). Graph MPATH:267 biolink:PathologicalEntityMixin glandular tumor Neoplasms derived from glandular epithelial cells. Graph MPATH:268 biolink:PathologicalEntityMixin adenocarcinoma Malignant neoplasm of epithelial cells in glandular or glandlike pattern. (M-8140/3). Graph MPATH:269 biolink:PathologicalEntityMixin adenocarcinoma in situ A noninvasive abnormal proliferation of glands believed to precede the appearance of invasive adenocarcinoma. (M-8140/2). Graph MPATH:270 biolink:PathologicalEntityMixin adenoma A benign epithelial neoplasm in which the tumor cells may form glands or glandlike structures. In different instances this may remain a benign tumor or progress to malignancy. Graph MPATH:271 biolink:PathologicalEntityMixin adenomatous polyposis coli Spontaneous intestinal adenoma formation. Polyps increase in number, causing symptoms of chronic colitis and potentially transform into adenocarcinoma. (M-8220/0). Graph MPATH:272 biolink:PathologicalEntityMixin bronchioloalveolar adenoma Benign epithelial neoplasm of the lung. (M-8140/1) 1.2.1.2 in MMHCC classification. Graph Bronchial adenoma|Bronchial adenoma, BA adenoma MPATH:273 biolink:PathologicalEntityMixin bronchioloalveolar carcinoma Malignant epithelial neoplasm of the lung. (M-8250/3) 1.2.3.2, 1.2.3.5 of MMHCC classification. Graph Bronchioloalveolar adenocarcinoma|Bronchioloalveolar adenocarcinoma, bronchioalveolar carcinoma MPATH:274 biolink:PathologicalEntityMixin clear cell adenocarcinoma An adenocarcinoma characterised by the presence of varying combinations of clear and hobnail-shaped tumor cells. (M-8310/3). Graph MPATH:275 biolink:PathologicalEntityMixin comedocarcinoma Form of carcinoma of the breast or other organ in which plugs of necrotic malignant cells are present in the ducts. (M -8501/3). Graph MPATH:276 biolink:PathologicalEntityMixin cystadenocarcinoma Malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. (M-8440/3). Graph MPATH:277 biolink:PathologicalEntityMixin cystadenoma A benign neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. (M-8440/0). Graph MPATH:278 biolink:PathologicalEntityMixin follicular adenocarcinoma Originates in the follicular cells of thyroid follicles. Papillary, solid and follicular forms. (M- 8330/3). Graph Follicular carcinoma MPATH:279 biolink:PathologicalEntityMixin follicular adenoma Adenoma derived from the follicular cells of the thyroid follicles. Follicular, paipillary and solid forms. M- 8330/0. Graph MPATH:280 biolink:PathologicalEntityMixin Harderian gland adenoma Adenoma derived from acinar epithelium of the harderian gland. Papillary, cystic, cystic-papillary and acinar forms. Graph MPATH:281 biolink:PathologicalEntityMixin Harderian gland carcinoma Malignant tumor derived form acinar epithelium of the Harderian gland. Graph MPATH:282 biolink:PathologicalEntityMixin infiltrating duct carcinoma Derived from the mammary ductal epithelium and penetrating the stroma (M-8500/3). Graph Infiltrating ductal adenocarcinoma|duct adenocarcinoma|ductal carcinoma MPATH:284 biolink:PathologicalEntityMixin intraductal papillary carcinoma Infiltrating tumor with papillary morphology derived from the breast epithelium (M-8503/3). Graph Intraductal papillary adenocarcinoma MPATH:285 biolink:PathologicalEntityMixin intraductal papilloma Benign papilloma arising from ductal epithelium (M- 8503/0 ). Graph Duct adenoma|ductal papilloma MPATH:286 biolink:PathologicalEntityMixin intraductal papillomatosis Diffuse multiple adenomatous papillomas derived from the ductal epithelium of the breast. (M- 8505/0). Graph Diffuse intraductal papillomatosis MPATH:287 biolink:PathologicalEntityMixin islet cell adenoma Usually pancreatic B cell derived tumors mostly producing insulin. (M- 8150/0). Graph Adenoma, endocrine pancreas|adenomatosis|islet (pancreatic) cell tumor benign MPATH:288 biolink:PathologicalEntityMixin islet cell carcinoma Rare tumor of the islets of Langerhans, most of which produce insulin. (M- 8150/3). Graph Adenocarcinoma, endocrine pancreas|islet cell tumor, malignant MPATH:289 biolink:PathologicalEntityMixin lobular carcinoma A form of breast adenocarcinoma derived from lobular cells. (M-8520/3). Graph Lobular adenocarcinoma|lobular infiltrating carcinoma MPATH:29 biolink:PathologicalEntityMixin cataract Opacity of the lens. Graph MPATH:290 biolink:PathologicalEntityMixin lobular carcinoma in situ Non-infiltrating form of lobular adenocarcinoma derived from the ductal epithelium. (M-8520/2). Graph mammary intra-epithelial neoplasia MPATH:291 biolink:PathologicalEntityMixin medullary carcinoma Derived from calcitonin-producing cells (thyroid). In humans a type of carcinoma composed of epithelial elements with considerable lymphoid stroma (breast). Not yet reported in mice. (M-8510/3). Graph Medullary adenocarcinoma MPATH:292 biolink:PathologicalEntityMixin mucinous cystadenocarcinoma Malignant neoplasm derived from a glandular epithelium, eg. Ovary. Consisting of a solid to cystic mass lined with cuboidal pleomorphic epithelial cells producing a mucinous material. (M- 8470/3). Graph MPATH:293 biolink:PathologicalEntityMixin mucinous cystadenoma A benign neoplasm derived from glandular epithelium, in which cystic accumulations of mucinous retained secretions are formed. (M-8470/0). Graph MPATH:294 biolink:PathologicalEntityMixin myoepithelioma Tumor originating in myoepithelial cells of exocrine glandular structures; for example mammary gland, salivary gland and preputial/clitoral glands. (M-8982/0). Graph myoepithelial adenoma MPATH:295 biolink:PathologicalEntityMixin papillary adenocarcinoma A malignant neoplasm derived from a glandular epithelium, in which solid tumors show papillary structures projecting onto fibrovascular stroma. (M-8260/3). Graph MPATH:296 biolink:PathologicalEntityMixin papillary adenoma A benign neoplasm derived from a glandular epithelium, in which solid tumors show papillary structures projecting onto fibrovascular stroma. (M-8260/0). Graph MPATH:297 biolink:PathologicalEntityMixin papillary cystadenocarcinoma A malignant neoplasm derived from glandular epithelium, in which cysts contain folds or papillary projections into the lumen. (M-8450/3). Graph MPATH:298 biolink:PathologicalEntityMixin papillary cystadenoma A benign neoplasm derived from glandular epithelium, in which cysts contain folds or papillary projections into the lumen. (M-8450/0). Graph MPATH:299 biolink:PathologicalEntityMixin pinealoma Originating from differentiated cells of the pineal parenchyma. Not to be confused with human pinealoma (syn: germinoma) non-gonadal germ cell tumors found in the pineal believed to be atypical teratomas. May be benign or malignant. If ectopic teratomas/teratocarcinomas use MP322 or MP321. (M-9360/1). Graph MPATH:300 biolink:PathologicalEntityMixin pineoblastoma Malignant neoplasms which arise from pineoblasts, the primitive pineal stem cells. (M-9362/3). Graph Mixed pineal tumor|pineal parenchymal tumor of intermediate differentiation|transitional pineal tumor MPATH:301 biolink:PathologicalEntityMixin pineocytoma A tumor arising in the pineal gland that resembles normal pineal parenchyma. (M-9361/1). Graph MPATH:302 biolink:PathologicalEntityMixin pituicytoma Benign tumor derived from the pituicytes ( glial cells of neurohypophysis) (M-8272/0). Graph pituitary adenoma MPATH:303 biolink:PathologicalEntityMixin pseudomyxoma peritonei Tumor characterized by extensive spread of a mucin-secreting neoplasm along the peritoneal surfaces (M-8480/6). Graph MPATH:304 biolink:PathologicalEntityMixin serous adenocarcinoma Adenocarcinoma from a serous gland producing and containing serous proteinaceous secretions (M-8441/3). Graph MPATH:305 biolink:PathologicalEntityMixin serous cystadenoma Ovarian cystadenoma composed of cells similar to tubal epithelium (M-8441/0). Graph MPATH:306 biolink:PathologicalEntityMixin signet ring cell carcinoma Adenocarcinoma of signet ring type arising from exocrine cells of the gastric mucosa or enterocytes of intestinal mucosa. (M-8490/3). Graph Signet ring cell adenocarcinoma|signet ring cell carcinoma MPATH:307 biolink:PathologicalEntityMixin thyroid C-cell adenoma Benign neoplasm derived from the calcitonin producing C-cells of the thyroid gland. Graph Adenoma, parafollicular cell|tumor c-cell benign MPATH:308 biolink:PathologicalEntityMixin thyroid C-cell carcinoma Malignant neoplasm derived from the calcitonin producing C-cells of the thyroid gland. (M-8510/3, M-8345/3). Graph Medullary carcinoma, parafollicular cell|tumor c-cell malignant MPATH:309 biolink:PathologicalEntityMixin gonadal tumor Germ cell and non-germ cell tumors of the testis and ovary. Graph MPATH:310 biolink:PathologicalEntityMixin germ cell tumor Neoplasms derived from germ cells. May be gonadal or extragonadal and are derived from primordial germ cells. Graph MPATH:311 biolink:PathologicalEntityMixin dermoid cyst Cystic ovarian teratomas with different mature cell types (M-9084/3). Graph MPATH:312 biolink:PathologicalEntityMixin dysgerminoma Undifferentiated germ cell tumor of the ovary composed of solid sheets of large polygonal cells with rim of clear cytoplasm (M-9060/3). Graph Seminoma (sensu male) MPATH:313 biolink:PathologicalEntityMixin embryonal carcinoma Germ cell derived malignant neoplasm of the testis or ovary, composed of anaplastic cells with indistinct cellular borders and large ovoid, round, or bean-shaped nuclei that may have large nucleoli. (M-9070/3 ). Graph MPATH:314 biolink:PathologicalEntityMixin endodermal sinus tumor Germ cell derived tumors resembling parietal or visceral yolk sac endoderm derivatives. Abundant eosinophilic matrix surrounding nests and cords of neoplastic cells. (M-9071-3). Graph Yolk sac carcinoma MPATH:315 biolink:PathologicalEntityMixin gonadoblastoma Gonadal neoplasms that consist of aggregates of germ cells and sex cord elements (M-9073/1). Graph Gonocytoma MPATH:316 biolink:PathologicalEntityMixin mixed germ cell tumor Malignant neoplasm of the testis/ovary including various elements of germ cell tumors (M-9085/3). Graph Mixed teratoma and seminoma MPATH:317 biolink:PathologicalEntityMixin seminoma Tumor derived from spermatogenic cells resembling spermatogenia or spermatocytes. NOS ( M9061/3). Graph Germinoma, malignant|dysgerminoma|spermatoblastoma|spermatocytoma, malignant. MPATH:318 biolink:PathologicalEntityMixin classical seminoma As MPATH:317, but not spermatocytic (M-9061/3). Graph MPATH:319 biolink:PathologicalEntityMixin spermatocytic seminoma Neoplasm of the testis usually found within the tubule. Some debate as to whether it is of germ cell origin in contrast to classical seminoma. Three types of cells are identified in spermatocytic seminomas: those with small, intermediate, and large nuclei in humans. (M-9063/3). Graph Spermatoma MPATH:320 biolink:PathologicalEntityMixin struma ovarii Rare ovarian tumor, regarded as monodermal teratoma, in which thyroid tissue has surpassed the other elements; occasionally associated with hyperthyroidism (M-9090/0). Graph MPATH:321 biolink:PathologicalEntityMixin teratocarcinoma Mixed germ cell neoplasm contaning elements of embryonal carcinoma and teratoma (M-9081/3). Graph MPATH:322 biolink:PathologicalEntityMixin teratoma Generally benign germ cell derived tumors of male or female containing derivatives from all three germ layers with differentiation in the malignant form being poor. Malignant tumors are highly metatstatic. (M-9080/1). Graph MPATH:323 biolink:PathologicalEntityMixin gonadal somatic cell tumor Neoplasms derived from the non-germ cell derived tissues of the testis and ovary. Graph MPATH:326 biolink:PathologicalEntityMixin granulosa cell tumor . Derived from sex cord stromal cells. In male thought to be Sertoli cells. (M- 8620/1). Graph Tumor, sex cord stromal, benign, granulosa cell type|gynoblastoma (sensu malignant form in ovary) MPATH:328 biolink:PathologicalEntityMixin leydig cell tumor Tumor derived from Leydig cells (M-8650/1). Graph Interstitial cell tumor, benign|Leydig cell adenoma MPATH:329 biolink:PathologicalEntityMixin luteal cell tumor Tumor derived from sex cords composed of highly luteinised cells with extensive pale granular cytoplasm. (M- 8610/0). Graph Luteoma|luteinised granulosa cell tumor, benign. Gonadal sex cord stromal tumor, benign, luteoma type MPATH:33 biolink:PathologicalEntityMixin intracellular and extracellular accumulation Accumulation of substances within, on the surface of or between cells. Graph MPATH:330 biolink:PathologicalEntityMixin ovarian stromal tumor Tumor consists of a mixture of granulosa, luteal thecal, Sertoli and stromal cells. (M-8590/1). Graph MPATH:331 biolink:PathologicalEntityMixin sertoli cell tumor Tumor derived from sex cord/stromal cells; Sertoli cells and can occur in both testis and ovary. (M-8640/1). Graph Androblastoma|arrhenoblastoma|gonadal stromal tumor|sex cord stromal tumor|sustentacluar tumor MPATH:332 biolink:PathologicalEntityMixin sertoli-leydig cell tumor Tumor of the ovary or testis containing granulosa or theca cell elements with a tubular componant of Sertoli cell type and producing simultaneous androgenic and estrogenic effects. (M-8631/0). Graph Gynandroblastoma MPATH:334 biolink:PathologicalEntityMixin thecoma Derived from sex cord stromal cells, spindle shaped cells arranged in whorls or interlacing bundles. (M- 8600/0). Graph Fibrothecoma|theca cell tumor MPATH:335 biolink:PathologicalEntityMixin hematopoietic/lymphoid malignancies/disorder Proliferative disorders and malignancies of the lymphoid and non lymphoid haematopoietic lineages. Graph MPATH:337 biolink:PathologicalEntityMixin erythroid leukaemia Leukaemia with at least 50% of nucleated erythroid cells infiltrating haematopoietic tissue. Graph MPATH:34 biolink:PathologicalEntityMixin amyloid deposition Extracellular deposition of amyloid protein. Graph Amyloidosis MPATH:340 biolink:PathologicalEntityMixin megakaryocytic leukaemia Leukaemia with at least 50% of megakaryocytic cells infiltrating haematopoietic tissue. Graph MPATH:341 biolink:PathologicalEntityMixin myelodysplastic disorder Haematopoietic proliferation with evidence of trilineage dysplasia. Less than 20% should be blasts. Graph MPATH:342 biolink:PathologicalEntityMixin myeloid leukaemia Leukaemias of the myeloid lineage. Graph granulocytic leukaemia MPATH:35 biolink:PathologicalEntityMixin bile deposition Intra- or extracellular deposition of bile pigments and their metabolites. Graph MPATH:351 biolink:PathologicalEntityMixin thymoma A neoplasm in the anterior mediastinum, originating from thymic tissue, usually benign, and frequently encapsulated; occasionally invasive, but metastases are rare; histologically, consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. (M-8580/1). Graph MPATH:352 biolink:PathologicalEntityMixin hepatic tumor Tumors of the liver and biliary apparatus. Graph MPATH:353 biolink:PathologicalEntityMixin hepatocellular adenoma Benign neoplasm derived from hepatocytes. (M- 8170/0). Graph hepatic adenoma, benign, liver cell tumor, benign|hepatoma, benign|nodule type A MPATH:354 biolink:PathologicalEntityMixin cholangiocarcinoma Malignant tumor derived from the bile duct epithelium. (M8160/3). Graph MPATH:355 biolink:PathologicalEntityMixin cholangiofibroma Develops from cholangiofibrosis, fibrosis of the biliary ducts and is only potentially malignant. Graph MPATH:356 biolink:PathologicalEntityMixin hepatoblastoma Malignant neoplasm of the liver of unknown origin . Liver blastemal cells, neoplastic hepatocytes, oval cells and biliary epithelial cells have been proposed. (M- 8970/3). Graph embryonal hepatoma|tumor, mixed, poorly differentiated MPATH:357 biolink:PathologicalEntityMixin hepatocellular carcinoma Malignant tumor derived from hepatocytes. (M- 8170/3). Graph carcinoma, trabecular|carcinoma, trabecular (liver)|hepatoma, malignant|nodule type B MPATH:358 biolink:PathologicalEntityMixin melanocytic tumor Tumors derived from melanocytes. Graph MPATH:359 biolink:PathologicalEntityMixin melanoma Tumor of neurectodermal origin, usually melanocytes, showing dense deposition of melanin granules, although amelanotic melanomas have been reported. (M-8720/3). Graph melanosarcoma|melanosarcoma, malignant melanoma MPATH:36 biolink:PathologicalEntityMixin calcium deposition Intra or extracellular deposition of calcium usually as calcium phosphate. Graph MPATH:360 biolink:PathologicalEntityMixin melanoma in situ A potentially malignant lesion, melanoma in situ is the first phase of growth of melanoma, in which it is still confined to the epithelial domain (epidermis and adnexa) and has not passed through the basement membrane. (M-8720/2). Graph level I melanoma MPATH:361 biolink:PathologicalEntityMixin naevus Local lesion of the skin, often colored by hyperpigmentation or increased vascularity. May be predominantly epidermal, adnexal, melanocytic, vascular, or mesodermal, or a compound overgrowth of these tissues. Not necessarily pre-malignant. (M-8720/0). Graph mole (sensu melanocytic nevus) MPATH:362 biolink:PathologicalEntityMixin mesonephroma Benign or malignant neoplasm of the ovary and corpus uteri, thought to originate in mesonephric structures. (M-9110/3). Graph mesonephric adenocarcinoma, wolffian duct carcinoma, mesonephroid tumor MPATH:363 biolink:PathologicalEntityMixin mesonephric tumor Tumor beleived to be derived from mesonephric remnants. (M-8310/3). Graph mesonephroid clear cell adenocarcinoma MPATH:365 biolink:PathologicalEntityMixin mesothelioma Benign or malignant neoplasm derived from the lining cells of the pleura and peritoneum, composed of spindle cells or fibrous tissue which may enclose glandlike spaces lined by cuboidal cells. Epithelioid, fibrous, cystis, papillary, and sarcomatoid variants. (M- 9050/3). Graph MPATH:366 biolink:PathologicalEntityMixin neuroendocrine tumor Neoplasms derived from the neuroendocrine system. Graph MPATH:367 biolink:PathologicalEntityMixin carcinoid tumor Carcinoid tumors are of neuroendocrine origin and derived from primitive stem cells. Found predominantly in the lung and gut they are capable of secreting a large range of substances and have a number of histological subtypes. May resemble but are distinct from small cell lung carcinoma in the lung. (M-8240/3). Graph MPATH:37 biolink:PathologicalEntityMixin ceroid deposition Intracellular deposition of golden or yellow-brown pigment, acid fast and insoluble in lipid solvents. Believed to be a type of lipofuscin. Graph MPATH:370 biolink:PathologicalEntityMixin primitive neurectodermal tumor Primitive neuroectodermal tumors (PNET) are neoplasms derived from primitive neural stem cells either in the CNS or the periphery . These are small-cell, malignant embryonal tumors showing divergent differentiation of variable degree along neuronal, glial, or rarely mesenchymal lines. (M-9473/3, M-9364/3). Graph PNET MPATH:371 biolink:PathologicalEntityMixin small cell carcinoma Neuroendocrine cell derived anaplastic carcinoma composed of small cells, usually of the lung producing a variety of peptide hormones. (M-8041/3). 1.2.3.4 of MMHCC classification. Graph oat cell carcinoma MPATH:372 biolink:PathologicalEntityMixin tumorlet Small disseminated foci of atypical bronchiolar epithelial hyperplasia. Benign. (M- 8040/1). Graph MPATH:373 biolink:PathologicalEntityMixin CNS progenitor tumor Neoplasms derived from neuroepithelial precursors. Graph MPATH:374 biolink:PathologicalEntityMixin esthesioneuroblastoma A neoplasm of immature, poorly differentiated neuronal cells believed to arise from neuroepithelial precursors in the olfactory epithelium. (M- 9522/3). Graph neuroblastoma, olfactory|neuroepithelial carcinoma|neuroepithelioma, olfactory MPATH:375 biolink:PathologicalEntityMixin ganglioneuroma A benign neoplasm composed of mature ganglionic neurons scattered singly or in clumps within a relatively abundant and dense stroma of neurofibrils and collagenous fibers. (M-9490/0). Graph MPATH:376 biolink:PathologicalEntityMixin neuroblastoma A malignant neoplasm characterized by immature, poorly differentiated nerve cells of embryonic type. (M-9500/3). Graph MPATH:377 biolink:PathologicalEntityMixin pheochromocytoma A catecholamine-secreting tumor arising from the chromaffin cells of the sympathetic nervous system or adrenal medulla. May be benign or malignant. [See MPATH 398]. (M- 8510/3). Graph MPATH:378 biolink:PathologicalEntityMixin retinoblastoma Malignant juvenile neoplasm of the eye derived from primitive retinal precursor cells. (M- 9510/3). Graph MPATH:379 biolink:PathologicalEntityMixin odontogenic tumor Neoplasm arising from the tissues of the odontogenic apparatus. These tumors are derived from ectodermal tissue (epithelial tumors) or from mesodermal tissue (connective tissue tumors) or are composed of both components (mixed or composite odontogenic tumors) . Graph MPATH:38 biolink:PathologicalEntityMixin copper deposition Intra and extracellular deposition of copper and copper containing proteins. Graph MPATH:380 biolink:PathologicalEntityMixin ameloblastic fibroma A tumor consisting of proliferating strands and clumps of odontogenic epithelium in a highly cellular fibroblastic stroma resembling the dental papilla of developing teeth. The epithelial component are composed of peripheral cuboidal or cylindrical cells enclosing scant stellate cells. (M-9330/0). Graph MPATH:381 biolink:PathologicalEntityMixin ameloblastoma Benign odontogenic epithelial neoplasm that histologically mimics the embryonic enamel organ but does not differentiate to the point of forming dental hard tissue. Histologically dominated by epithelial cells in a scant fibroblastic stroma. (M-9310/0). Graph MPATH:382 biolink:PathologicalEntityMixin cementifying fibroma Benign neoplasm derived from pluripotential mesenchymal cells or cementoblasts. Well demarcated tumor occurring exclusively in the jaw containing spindle cells which undergo transformation to cuboidal cementoblasts forming multiple cementicle like bodies. ( M-9274/0). Graph ossifying fibroma, cemento-ossifying fibroma MPATH:383 biolink:PathologicalEntityMixin cementoblastoma A neoplasm arising from the periodontal ligament (M-9273/0). Graph True cementoma MPATH:384 biolink:PathologicalEntityMixin cementoma Reactive fibro-osseous lesion derived from odotongenic cells in the periodontal ligament (M-9272/0). Graph MPATH:385 biolink:PathologicalEntityMixin dentinoma Similar lesion to ameloblastic fibroma (MPATH380) , but also showing inductive changes that lead to the formation of dentine (M-9271/0). Graph ameloblastic fibrodentinoma MPATH:387 biolink:PathologicalEntityMixin odontoma Hamartomatous malformation of odontogenic tissue. It may vary from nondescript masses of dental tissue (complex odontoma) to multiple well-formed teeth (compound odontoma). Cf ameloblastic fibro-odontoma. (M-9280/0). Graph MPATH:388 biolink:PathologicalEntityMixin osseous and chondromatous tumor Neoplasms of bone and cartilage. Graph MPATH:389 biolink:PathologicalEntityMixin chondroblastoma A benign or malignant neoplasm occuring in the epiphyses of long bones, consisting of highly cellular tissue resembling embryonic cartilage. (M-9230/0, /3). Graph MPATH:39 biolink:PathologicalEntityMixin glycogen deposition Intracellular deposition of glycogen. Graph MPATH:391 biolink:PathologicalEntityMixin chondroma A benign neoplasm derived from mesodermal cells that form cartilage composed of well differentiated hyaline cartilage (M-9220/0). Graph MPATH:392 biolink:PathologicalEntityMixin chondrosarcoma Malignant neoplasm derived form pluripotential mesenchymal cells, chondrocytes or chondroblasts. No production of osteoid. (M-9220/3). Graph MPATH:393 biolink:PathologicalEntityMixin osteoblastoma Generally benign osteogenic neoplasm of unknown aetiology. Aggressive form may be confused with osteosarcoma. NOT a syn for osteofibroma. (M-9200/0). Graph giant osteoid osteoma, benign osteoblastoma MPATH:394 biolink:PathologicalEntityMixin osteochondroma Benign bone tumor characterized by hyaline cartilage capped bony growths that project from the surface of the affected bone. (M-9210/0). Graph cartilaginous exostosis MPATH:395 biolink:PathologicalEntityMixin osteofibroma Benign neoplasm derived from pluripotential mesenchymal stem cells or osteoblasts composed of mature nbone trabelculae seperated by a stroma of spindle cells. (M- 9262/0). Graph MPATH:396 biolink:PathologicalEntityMixin osteoma Benign neoplasm derived from osteoblasts or osteocytes composed of very dense bone with predominantly woven structure. ( M-9180/0). Graph cancellous osteoma|compact osteoma|juxtacortical osteoma|medullary osteoma|osteoid osteoma|spongious osteoma|trabecular osteoma MPATH:397 biolink:PathologicalEntityMixin osteosarcoma Malignant neoplasm derived form mesenchymal stem cells, osteoblasts or osteocytes. Highly invasive and destructive tumor rising in the skeleton with osteoid and immature woven bone. (M-9180/3). Graph osteogenic sarcoma MPATH:398 biolink:PathologicalEntityMixin paragangliomas and glomus tumor Generally benign neoplasms of CHIEF cells arising from neuroectodermal tissues, found in various parts of the body. Note that until recently, glomus tumors were believed to be derived from specialised vascular cells, which is incorrect. Paraganglioma is the preferred term.The nomenclature for pheochromocytoma and paraganglioma is inconsistent. The term paraganglioma is used to refer to any extra-adrenal tumor of the paraganglion system or nonfunctional tumor of the paraganglion system. Functional tumors are referred extra-adrenal pheochromocytoma. Graph MPATH:399 biolink:PathologicalEntityMixin aortic body tumor Paraganglioma arising in the CHIEF cells of the aortic body (M-8691/1). Graph aortic body paraganglioma MPATH:40 biolink:PathologicalEntityMixin hyalinosis Intracellular deposition of eosinophilic material. Graph Hyaline degeneration, Eosinophilic cytoplasmic change MPATH:400 biolink:PathologicalEntityMixin carotid body tumor Paraganglioma arising in the CHIEF cells of the carotid body (M-8692/1). Graph carotid body paraganglioma MPATH:401 biolink:PathologicalEntityMixin glomus jugulare tumor A glomus tumor arising from the chief cells of the paraganglia ( neurectodermal derivatives) , or glomus bodies, located within the wall (adventitia) of the jugular bulb. (8690/1). Graph MPATH:403 biolink:PathologicalEntityMixin paraganglioma A neoplasm composed of derivatives of CHIEF cells usually in single encapsulated nodular masses surrounded with sustentacular cells. ( M- 8711/0). Graph chemodectomas|glomus tumor|non-chromaffin paragangliomas MPATH:404 biolink:PathologicalEntityMixin soft tissue tumor Neoplasms of the soft and connective tissues. Graph MPATH:405 biolink:PathologicalEntityMixin chordoma Believed to arise from primitive notochord remnants . Usually occurs along the axial skeleton and is characterised by the presence of bubble cells containing large unstained cytoplasmic vacuoles with central or eccentricc nuclei. Benign but locally invasive. (M-9370/3). Graph MPATH:406 biolink:PathologicalEntityMixin dermatofibrosarcoma Highly recurrent, infiltrative skin tumors of intermediate malignancy derived from fibroblasts/fibrocytes. Human condition dermatofibrosarcoma protruberans (M-8832/3). Graph MPATH:407 biolink:PathologicalEntityMixin fibroma Benign neoplasm of fibroblasts/fibrocytes with poor/moderate cellularity. (M-8810/0). Graph MPATH:408 biolink:PathologicalEntityMixin soft tissue fibrosarcoma Malignant tumor derived from pluripotential mesenchymal stem cells; fibroblasts, fibrocytes (M-8810/3). Graph fibrosarcoma MPATH:409 biolink:PathologicalEntityMixin fibrous histiocytoma Benign or maligant tumor derived from pluripotential mesenchymal stem cells showing fibrous and histiocytic differentiation (M-8830/0). Graph MPATH:41 biolink:PathologicalEntityMixin iron deposition Extra- or intra-cellular deposition of iron, iron containing proteins or hemosiderin. Graph MPATH:410 biolink:PathologicalEntityMixin giant cell tumor of soft tissue Malignant or benign tumor of pluripotential mesenchymal stem cells giving rise to large multinucleated cells (M- 9251/1). Graph giant cell fibrous histiocytoma MPATH:412 biolink:PathologicalEntityMixin alveolar soft part sarcoma Malignant tumor of unknown origin though probably myogenic due to expression of MyoD and other myogenic lineage markers. Consists of grouped polygonal tumor cells with granular eosinophilic cytoplasm arranged in an organ-like configuration separated by thin fibrovascular septa. Central areas within these nests of cells become necrotic, and the loss of architecture produces an alveolar appearance. (M-9581/3). Graph MPATH:413 biolink:PathologicalEntityMixin granular cell tumor Large polygonal or round cell tumors with abundant acidophilic cytoplasm containing PAS positive granules. Found especially in the uterine cervix. Aetiology unknown. (M-9580/0). Graph myoblastoma MPATH:415 biolink:PathologicalEntityMixin lipomatous tumor Tumors derived from the lipogenic lineage or showing predominantly lipomatous differentiation. Graph MPATH:416 biolink:PathologicalEntityMixin angiomyolipoma Benign renal neoplasm composed of fat, vascular, and smooth muscle elements. Associated with tuberous sclerosis in humans. Aetiology unknown, but the combination of elements may reflect a lesion specific pattern of metaplasia. (M-8860/0). Graph MPATH:417 biolink:PathologicalEntityMixin lipoma Benign neoplasia derived from lipoblasts or lipocytes of white or brown fat. May be angiomatous or hibernomatous. (M- 8850/0). Graph MPATH:418 biolink:PathologicalEntityMixin liposarcoma Malignant neoplasms which probably originate in primitive mesenchymal stem cell populations differentiating down a lipomatous pathway. (M-8850/3). Graph MPATH:419 biolink:PathologicalEntityMixin lymphatic vessel tumor Neoplasms of the lymphatic vessels. Graph MPATH:42 biolink:PathologicalEntityMixin lipid deposition Extra or intracellular deposition of lipid. Graph MPATH:420 biolink:PathologicalEntityMixin lymphangioma Benign hamartomatous malformation of the lymphatic ducts. Usually found in the skin and may be superficial or deep. (M-9170/0). Graph Hygroma MPATH:421 biolink:PathologicalEntityMixin lymphangiomyomatosis Characterized by benign peribronchial, perivascular, and perilymphatic proliferation of atypical smooth muscle resulting in vascular and airway obstruction, cyst formation, and a progressive decline in lung function. (M- 9174/1). Graph Lymphangioleiomyomatosis. MPATH:422 biolink:PathologicalEntityMixin lymphangiosarcoma A malignant neoplasm derived from vascular tissue in which the neoplastic cells originate from the endothelial cells of lymphatic vessels. (M-9170/3). Graph MPATH:423 biolink:PathologicalEntityMixin myomatous tumor Neoplasms derived from myogenic lineages or predominantly composed of cells showing myomatous differentiation. Graph MPATH:424 biolink:PathologicalEntityMixin intravascular leiomyomatosis Benign leiomyoma that invades vascular spaces. (M-8890/1). Graph MPATH:425 biolink:PathologicalEntityMixin leiomyoma Benign neoplasm derived from smooth muscle cells. (M-8890/0). Graph MPATH:426 biolink:PathologicalEntityMixin leiomyosarcoma Malignant tumor derived form pluripotential mesenchymal stem cells or smooth muscle cells. (M- 8890/3). Graph MPATH:428 biolink:PathologicalEntityMixin rhabdomyosarcoma Malignant tumor of striated muscle or pluripotential mesenchymal stem cells. (M-8900/3). Graph MPATH:429 biolink:PathologicalEntityMixin myxomatous tumor Neoplasms resembling primitive mesenchymal tissue with a soft mucous matrix. Graph MPATH:43 biolink:PathologicalEntityMixin lipofuscin deposition Intracellular deposition of brown pigment granules probably representing lipid-containing residues of lysosomal digestion. Often age related. Graph MPATH:430 biolink:PathologicalEntityMixin angiomyxoma Angiomyxoma is a poorly circumscribed, slowly growing lesion composed of spindle-shaped and stellate cells evenly distributed in an abundant myxoid matrix. The lesion contains numerous vessels, often showing some hyalinization of their walls, and occasionally surrounded by a few smooth muscle cells. Immunohistochemically, tumor cells may express desmin and/ or smooth muscle actin (M-8841/1). Graph MPATH:431 biolink:PathologicalEntityMixin myxoma A benign neoplasm derived from pluripotential mesenchymal stem cells of connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix. May show multiple differentiated components. (M-8840/0). Graph MPATH:432 biolink:PathologicalEntityMixin myxosarcoma A malignant neoplasm derived from pluripotential mesenchymal stem cells of connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix. (M-8840/3). Graph MPATH:433 biolink:PathologicalEntityMixin nerve sheath tumor Neoplasms of the nerve sheath. Graph MPATH:435 biolink:PathologicalEntityMixin neurofibroma Peripheral nerve tumor consisting of chaotic arrays of wavy schwann cell bundles and fibroblasts interspersed within a matrix rich in collagen and mucopolysaccharide. (M9540/0). Graph MPATH:436 biolink:PathologicalEntityMixin neurofibromatosis Systemic manifestation of MPATH:435 ( M-9540/1). Graph MPATH:437 biolink:PathologicalEntityMixin neurofibrosarcoma Malignant neoplasm derived from Schwann cells. (M-9540/3). Graph malignant peripheral nerve sheath tumor MPATH:438 biolink:PathologicalEntityMixin schwannoma May be malignant or benign, Schwann cell derived tumor considered to be neurectodermal with some acquired mesenchymal features. (M-9560/0). Graph neurilemoma|neurinoma, benign MPATH:439 biolink:PathologicalEntityMixin synovial-like tumor Neoplasms of synovial origin. Graph MPATH:44 biolink:PathologicalEntityMixin melanin deposition Intra or extracellular deposition of melanin. Graph MPATH:440 biolink:PathologicalEntityMixin synovial sarcoma Malignant neoplasm occurring in close association with tendon sheaths and joint capsules. Biphasic in humans , showing a mixed spindle cell and epithelioid like morphology; this is not seen in rodents to date. (M-9040/3). Graph Synovial cell sarcoma MPATH:442 biolink:PathologicalEntityMixin squamous cell tumor Neoplasms of stratified squamous epithelial cells. Graph MPATH:443 biolink:PathologicalEntityMixin inverted squamous papilloma A benign tumor consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic epithelial cells in which proliferating epithelium is invaginated beneath the surface and is more smoothly rounded. (M-8053/0). Graph endophytic papilloma|invaginated papilloma MPATH:444 biolink:PathologicalEntityMixin keratoacanthoma Skin type is thought to arise from follicular epithelium of hair follicles; found in other epithelia. Composed of multiple cup shaped cavities filled with lamellated concentrically arranged or homogeneous cornified masses. Graph epithelioma, intracutaneous, cornifying MPATH:445 biolink:PathologicalEntityMixin papilloma A benign tumor consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic epithelial cells (M-8050/0). Graph MPATH:446 biolink:PathologicalEntityMixin squamous cell carcinoma Malignant tumor derived from stratified squamous cells. (M-8070/3). Graph carcinoma, epidermoid ( sensu epidermal derived tumors) MPATH:447 biolink:PathologicalEntityMixin squamous cell carcinoma in situ Pre-neoplastic intraepithelial lesion of squamous cells (M-8070/2). Graph IENIII|severe intra-epithelial neoplasia MPATH:448 biolink:PathologicalEntityMixin squamous cell papilloma A benign tumor consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic squamous epithelial cells. Graph Exophytic papilloma MPATH:449 biolink:PathologicalEntityMixin verrucous carcinoma A well-differentiated papillary squamous cell carcinoma. (M-8051/3). Graph MPATH:45 biolink:PathologicalEntityMixin protein deposition Non-specified intra or extracellular deposition of protein. Graph MPATH:450 biolink:PathologicalEntityMixin transitional cell tumor Neoplasms of transitional epithelia, eg kidney, ureter , bladder , cervix. Graph MPATH:451 biolink:PathologicalEntityMixin transitional cell carcinoma Malignant neoplasm of transitional cells (M-8120/3). Graph MPATH:452 biolink:PathologicalEntityMixin transitional cell carcinoma in situ Pre-malignant intra-epithelial neoplasm of transitional cells (M-8120/2). Graph severe intra-epithelial neoplasia MPATH:453 biolink:PathologicalEntityMixin transitional cell papilloma Pre-malignant lesion of transitional cells, papillomatous form ( M- 8120/1). Graph MPATH:454 biolink:PathologicalEntityMixin trophoblastic tumor Tumors derived directly from trophoblastic tissue or differentiated from germ cell tumor origins. Graph MPATH:455 biolink:PathologicalEntityMixin choriocarcinoma Tumor derived from malignant trophoblastic cells. May be found in the uterus, ovary and testis. May also be derived from teratomas and teratocarcinomas in males. (M-9100/3). Graph Chorioepithelioma, malignant. MPATH:456 biolink:PathologicalEntityMixin hydatidiform mole Vesicular or cystic tumor with hydropic villi resulting from the proliferation of trophoblast in the absence ( complete) or the presence ( partial) of an embryo. Most complete moles are homozygous androgenetic XX 46.(M-9100/0). Graph cystic mole|gestational trophoblastic disease MPATH:457 biolink:PathologicalEntityMixin placental site trophoblastic tumor Neoplastic proliferation of intermediate trophoblasts that invades the myometrium at the placental site after a pregnancy. (M-9104/1). Graph MPATH:46 biolink:PathologicalEntityMixin uric acid deposition Extracellular deposition of uric acid crystals. Graph MPATH:460 biolink:PathologicalEntityMixin nuclear defect Defect in the structure or function of the nuclear membrane or matrix or other component. Graph MPATH:461 biolink:PathologicalEntityMixin cataract; capsular-epithelial Proliferation of lens epithelium and capsule leading to fibrous metaplasia and anterior subcapsular cataract ( ASC) . Possible developmental origin. Graph MPATH:462 biolink:PathologicalEntityMixin cataract; nuclear and cortical Nuclear cataract of developmental origin with tendency to progress with age and involve the cortex and capsule. Graph MPATH:463 biolink:PathologicalEntityMixin cataract; cortical liquefactive Of developmental origins; nucleus and cortex become completely liquefied in post-natal life. Graph MPATH:464 biolink:PathologicalEntityMixin cataract; lens extrusion Involves capsular rupture usually of the posterior lens capsule, close to birth or in the first few weeks postpartum. Cortical material spills into the vitreous humor and may be disseminated through the eye. Graph MPATH:468 biolink:PathologicalEntityMixin pseudocyst Formation of extracellular (sensu pancreas) non-epithelial bounded spaces containing accumulated products or substances. Graph MPATH:469 biolink:PathologicalEntityMixin symmetry defect Any aberration of the normal symmetrical organisation of the body pattern. Graph MPATH:47 biolink:PathologicalEntityMixin intracellular and extracellular depletion Loss or dispersion of specific intra- and extracellular substances. Graph MPATH:470 biolink:PathologicalEntityMixin left/right axis defect Left/Right (mediolateral) axis aberration of the normal symmetrical organisation of the body pattern. Graph MPATH:471 biolink:PathologicalEntityMixin anterior/posterior axis defect Anteroposterior aberration of the normal symmetrical organisation of the body pattern. Graph MPATH:472 biolink:PathologicalEntityMixin dorsal/ventral axis defect Dorsoventral aberration of the normal symmetrical organisation of the body pattern. Graph MPATH:474 biolink:PathologicalEntityMixin ectasia Dilation of a tubular structure. Graph MPATH:475 biolink:PathologicalEntityMixin ductal ectasia Dilation of a ductal structure. Graph MPATH:476 biolink:PathologicalEntityMixin telangiectasia A lesion formed by a dilated capillary or terminal artery. Graph MPATH:477 biolink:PathologicalEntityMixin choristoma Similar to hamartoma, including the mass lesion requirement, but unlike hamartoma, includes heterotopic tissue of an adult or embryonic nature ( topographical and developmental anomaly). Graph Choristoblastoma MPATH:48 biolink:PathologicalEntityMixin decalcification Process of loss of calcium from normally calcified tissue, usually bone. Graph MPATH:480 biolink:PathologicalEntityMixin decidual defect Any defect in the formation, architecture, cellular composition or function of the maternal decidua. Graph MPATH:482 biolink:PathologicalEntityMixin focal hyperplasia Localised hyperplastic lesion. Polyclonal lesions are probably benign but clonal lesions may progress to malignancy. Graph MPATH:484 biolink:PathologicalEntityMixin hyperplastic nodule Expansion of small hyperplastic lesions to become macroscopically nodules, compressing adjacent cells. Graph hyperplastic nodules|nodular hyperplasia MPATH:486 biolink:PathologicalEntityMixin ductal intra-epithelial neoplasia Pre-malignant hyperplastic and/or dysplastic change in the mammary gland epithelium with the potential to give rise to malignant tumors. Graph DIN|Ductal carcinoma in situ|MIN|intraductal adenocarcinoma, non-infiltrating|mammary intra-epithelial neoplasia MPATH:487 biolink:PathologicalEntityMixin intestinal intra-epithelial neoplasia Histologically apparent areas of dysplasia that are not grossly visible (smaller than 0.5-1 mm). Lesions may involve single or multiple glands. Graph GIN|IIN|microadenoma MPATH:488 biolink:PathologicalEntityMixin prostate intra-epithelial neoplasia See reference for definition. Graph PIN MPATH:489 biolink:PathologicalEntityMixin stomach, oesophagus and pancreatic intra-epithelial neoplasia stomach, oesophagus and pancreatic intra-epithelial neoplasia Graph PANIN MPATH:49 biolink:PathologicalEntityMixin demyelination Reduction of myelin content in neuronal sheath. Graph MPATH:490 biolink:PathologicalEntityMixin adenomatous polyp Benign neoplastic growth containing areas of adenomatous structure (progression). Graph polypoid adenoma, cellular polyp. MPATH:491 biolink:PathologicalEntityMixin polyp A mass of tissue which projects outward or upward from the normal surface level being macroscopically visible as a hemispheroidal, spheroidal, or irregular moundlike structure growing from a relatively broad base or a slender stalk. Graph MPATH:495 biolink:PathologicalEntityMixin glomangioma Tumor derived from the capillary glomus with arteriovenous capillary anastomoses. Often characterized by multiple tumors resembling cavernous hemangioma (M-8712/0). Graph MPATH:496 biolink:PathologicalEntityMixin Non-Lymphoid leukaemias Neoplasms of non-lymphoid haematopoietic lineage. Must have at least 20% blast cells to meet this definition. Graph MPATH:497 biolink:PathologicalEntityMixin myeloid leukaemia without maturation Leukaemia in which neoplastic cells are poorly differentiated and not monocytic. At least 90% of the cells have to be blasts. Graph myeloblastic leukaemia without maturation|myeloid leukaemia (myeloblastic type)|poorly differentiated myeloid leukaemia MPATH:498 biolink:PathologicalEntityMixin myeloid leukaemia with maturation Leukaemia in which neoplastic cells are moderately differentiated with a neutrophilic but not monocytic component. At least 20% of the cells have to be blasts. Graph myeloblastic laeukaemia with maturation|poorly differentiated myeloid leukaemia MPATH:50 biolink:PathologicalEntityMixin glycogen depletion Reduction in intracellular glycogen content. Graph MPATH:500 biolink:PathologicalEntityMixin myeloproliferative disease-like myeloid leukaemia Leukaemia in which neoplastic cells are well differentiated and in which there are fewer than 20% blasts. Graph myeloid leukaemia, chonic type|well differentiated myeloid leukaemia MPATH:501 biolink:PathologicalEntityMixin myelomonocytic leukaemia Leukaemia in which neoplastic cells are moderately differentiated with a neutrophilic and a monocytic component. At least 20% of the cells have to be blasts. Graph myeloid leukaemia, myelomonocytic type MPATH:502 biolink:PathologicalEntityMixin monocytic leukaemia Leukaemia in which neoplastic cells are poorly or moderately differentiated with a monocytic but no neutrophilic component. At least 20% of the cells must be blasts. Graph MPATH:503 biolink:PathologicalEntityMixin biphenotypic leukaemia A leukaemia with at least 90% blasts and differentiation markers of the myeloid and lymphoid lineage. Graph MPATH:504 biolink:PathologicalEntityMixin non-lymphoid hematopoietic sarcomas Solid tumor mass composed of non-lymphoid haematopoietic cells. Graph MPATH:505 biolink:PathologicalEntityMixin granulocytic sarcoma Solid tumor mass composed predominantly of granulocytic or relatively undifferentiated non-lymphoid haematopoietic cells. Graph MPATH:506 biolink:PathologicalEntityMixin histiocytic sarcoma Solid tumor mass composed predominantly of histiocytic cells (M-9775/3). Graph Kupffer cell sarcoma (sensu liver)|histiocytic lymphoma|malignant lymphoma, histiocytic type|reticulum cell sarcoma, type A|reticulum cell sarcoma, type A, reticulosarcoma MPATH:507 biolink:PathologicalEntityMixin mast cell sarcoma Solid tumor mass composed of mast cells. Graph malignant mastocytoma|mast cell tumor|mastocytosis MPATH:508 biolink:PathologicalEntityMixin myeloid dysplasias Haematopoietic proliferation with evidence of trilineage dysplasia. Graph MPATH:509 biolink:PathologicalEntityMixin cytopenia with increased blasts Haematopoietic proliferation with evidence of trilineage dysplasia. More than 20% should be blasts. Graph MPATH:51 biolink:PathologicalEntityMixin hypocalcification Intrinsic abnormally low level of calcification in a tissue cf. MPATH: 48. Graph MPATH:510 biolink:PathologicalEntityMixin myeloid proliferations (non-reactive) Non-reactive persistent accumulation of non-lymphoid haematopoietic cells. Genetically determined. Graph MPATH:511 biolink:PathologicalEntityMixin myeloproliferation (genetic) Non-reactive persistent accumulation of non-lymphoid haematopoietic cells in the blood which do not infiltrate the spleen and the bone marrow. Genetically determined. Graph MPATH:512 biolink:PathologicalEntityMixin myeloproliferative disease Non-reactive persistent accumulation of non-lymphoid haematopoietic cells in the blood which infiltrate the spleen and the bone marrow. Graph MPATH:513 biolink:PathologicalEntityMixin lymphoid neoplasms Neoplasms of the B or T cell lineage. Graph MPATH:515 biolink:PathologicalEntityMixin non-Lymphoid neoplasias Hematological neoplasias of non-lymphoid origin. Graph MPATH:516 biolink:PathologicalEntityMixin B-cell neoplasms Neoplasm of the B cell lymphoid lineage. Graph MPATH:517 biolink:PathologicalEntityMixin precursor B cell neoplasms Lymphoma originating from precursor B-cells. Graph MPATH:518 biolink:PathologicalEntityMixin precursor B -cell lymphoblastic lymphoma/leukaemia Lymphoma originating in a precursor B-cell. Graph lymphoblastic leukaemia|lymphoblastic lymphoma MPATH:519 biolink:PathologicalEntityMixin mature B-cell neoplasms Lymphomas originating in peripheral B cells. Graph MPATH:52 biolink:PathologicalEntityMixin lipid depletion Reduction in cellular or plasma lipid content. Graph MPATH:520 biolink:PathologicalEntityMixin small B-cell lymphoma Diffuse accumulation of small mature B-cells. Graph small lymphocytic lymphoma|well differentiated lymphocytic lymphoma MPATH:521 biolink:PathologicalEntityMixin splenic marginal zone lymphoma A lymphoid proliferation of cells of the marginal zone of the white pulp of the spleen. Graph SMZL MPATH:522 biolink:PathologicalEntityMixin follicular B cell lymphoma A lymphoid proliferation composed of a mixture of centroblasts and centrocytes that may or may not have a nodular(follicular)pattern. The follicular dendritic cell network is not present, unlike in the human. The equivalent typical translocation (Chr. 14:18 )seen in humans has not been reported in the mouse. Graph centroblastic/centrocytic lymphoma|follicular center cell lymphoma, small cell or mixed|follicular lymphoma MPATH:523 biolink:PathologicalEntityMixin diffuse large B-cell lymphoma Diffuse proliferation of large B lymphoid cells. Graph DLBCL MPATH:524 biolink:PathologicalEntityMixin diffuse large B-cell lymphoma, centroblastic type Diffuse follicular centre cell lymphoma mainly composed of centroblasts. Graph centroblastic lymphoma MPATH:525 biolink:PathologicalEntityMixin diffuse large B-cell lymphoma, immunoblastic type Diffuse large B cell lymphoma with increased number of immunoblasts. Graph Immunoblastic lymphoma MPATH:526 biolink:PathologicalEntityMixin diffuse large B-cell lymphoma, histiocyte associated Diffuse large B-cell lymphoma with more than 50% histiocytes. Graph DLCL (HS) MPATH:527 biolink:PathologicalEntityMixin primary mediastinal (thymic) diffuse large B cell lymphoma Primary B-cell lymphoma of the thymus. Reported in C57BL/6 mice infected with replication defective MuLV. Not clear that this is the equivalent of the human disease. Graph MPATH:528 biolink:PathologicalEntityMixin classic Burkitt lymphoma Highly proliferative B-cell lymphoma characteristically seen in c-Myc transgenic mice, derived from mature B cells. Graph MPATH:529 biolink:PathologicalEntityMixin Burkitt-like lymphoma Highly proliferative mature B-cell lymphoma, poorly defined. Graph MPATH:53 biolink:PathologicalEntityMixin osteopenia Reduced bone mass due to inadequate synthesis of osteoid, resulting in decreased calcification. Graph MPATH:530 biolink:PathologicalEntityMixin plasma cell neoplasms Diffuse proliferation of mature plasma cells. Clonal by definition. Includes the equivalent of human myeloma (ICD-O 9732/3). Graph Myeloma ( human ) MPATH:531 biolink:PathologicalEntityMixin B-natural killer cell lymphoma Unusual lymphoma type described in thymectomised (SL/Kh x AKR/Ms) F1 mice. No equivalent found in human to date. See reference for detailed phenotype. Graph MPATH:532 biolink:PathologicalEntityMixin plasmacytoma Diffuse proliferation of mature plasma cells. Clonal by definition. Graph MPATH:533 biolink:PathologicalEntityMixin extraosseous plasmacytoma Diffuse proliferation of mature plasma cells. Clonal by definition. Frequently found in IL6 transgenic mice. Characteristically involves spleen and nodes rather than peritoneum. Graph MPATH:534 biolink:PathologicalEntityMixin anaplastic plasmacytoma Diffuse proliferation of immature plasma cells or plasma blasts. Graph MPATH:535 biolink:PathologicalEntityMixin T-cell neoplasms Neoplasms derived from cells of the T lymphocyte lineage. Graph MPATH:536 biolink:PathologicalEntityMixin precursor T-cell neoplasms Neoplasms of precursor T cells. Graph MPATH:537 biolink:PathologicalEntityMixin precursor T-cell lymphoblastic lymphoma/leukaemia Precursor T cell derived neoplasia. Most commonly found in the thymus. Graph thymic lymphoma MPATH:538 biolink:PathologicalEntityMixin mature T-cell neoplasms Non-thymic neoplasms of mature T cell origin. Graph MPATH:539 biolink:PathologicalEntityMixin small T-cell lymphoma Accumulation of small mature T cells. No human counterpart known to date. Graph MPATH:54 biolink:PathologicalEntityMixin osteoporosis Reduction in the quantity of bone or atrophy of skeletal tissue. More severe than MPATH: 53 with gross changes to bone matrix. Graph MPATH:540 biolink:PathologicalEntityMixin T cell neoplasms character undetermined T cell neoplasms which cannot currently be classified into known subtypes. Graph MPATH:541 biolink:PathologicalEntityMixin T large cell anaplastic lymphoma Diffuse large pleiomorphic T cell lymphoma. This entity does not correspond to human anaplastic large cell lymphoma. Graph MPATH:542 biolink:PathologicalEntityMixin T natural killer cell lymphoma Neoplasm of large granular T cells of CD8 phenotype. Graph MPATH:543 biolink:PathologicalEntityMixin cholangioma Benign neoplasm of the biliary duct. Occurs in solid and cystic forms. (M-8160/0). Graph MPATH:544 biolink:PathologicalEntityMixin hepatocholangiocellular adenoma Benign tumor of unknown origin showing features of hepatocelluar adenoma and cholangioma. Graph MPATH:545 biolink:PathologicalEntityMixin hepatocholangiocellular carcinoma Malignant tumor of unknown origin showing features of hepatocelluar carcinoma and cholangiocarcinoma. (M-8180/3). Graph MPATH:547 biolink:PathologicalEntityMixin mucous secretions Extracellular accumulation of mucous secretions. Graph MPATH:548 biolink:PathologicalEntityMixin papillary transitional cell carcinoma A generally malignant neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by atypical neoplastic epithelial or urothelial cells cells. Graph MPATH:549 biolink:PathologicalEntityMixin carcinoma Any of various types of malignant neoplasm derived from epithelial cells, chiefly glandular (adenocarcinoma) or squamous (squamous cell carcinoma). Graph MPATH:55 biolink:PathologicalEntityMixin developmental and structural abnormality Developmental and structural abnormalities occurring during embryonic development or during adult life. Graph MPATH:551 biolink:PathologicalEntityMixin sarcoma A connective tissue neoplasm, usually highly malignant, formed by proliferation of mesodermal cells. Graph MPATH:555 biolink:PathologicalEntityMixin mineralisation Deposition of any homogeneous inorganic material. Graph MPATH:556 biolink:PathologicalEntityMixin potentially cancerous lesions Lesions which in some cases have the potential to become progressively growing malignant tumors. Graph MPATH:558 biolink:PathologicalEntityMixin adenomyoepithelioma Adenocarcinoma type tumor with both glandular and squamous differentiation. (M-8983/0). Graph MPATH:559 biolink:PathologicalEntityMixin acinar adenocarcinoma Tumor composed of small glandular clusters with small lumens. Graph MPATH:56 biolink:PathologicalEntityMixin developmental or adult structural defect Structural, physical or other general defect of prenatal development of the embryo and the placenta, or such as are acquired in the adult. Graph MPATH:560 biolink:PathologicalEntityMixin cribriform adenocarcinoma Tumor composed of sheets or nests of cells forming lumens with round, punched out spaces. Graph MPATH:561 biolink:PathologicalEntityMixin adenosquamous carcinoma Mixed adeno- and squamous cell carcinoma. Not yet reported in mice. M-8560/3. Graph MPATH:562 biolink:PathologicalEntityMixin torsion The twisting of a bodily organ or part on its own axis. Graph MPATH:563 biolink:PathologicalEntityMixin mucinous carcinoma carcinoma derived from gastrointestinal epithelium with a high mucinous content. (M-8480/3). Graph mucinous adenocarcinoma MPATH:564 biolink:PathologicalEntityMixin glioblastoma Develop primarily through increasing anaplasia of well differentiated gliomas, mainly astrocytomas or oligodendrogliomas. Typically large and contain cells of different sizes with irrregular nuclei and atypical mitotic figures. (M-9440/3). Graph glioblastoma multiforme|monstrocytoma MPATH:565 biolink:PathologicalEntityMixin tumors of neurepithelial tissue Tumors of neuronal and non-neuronal cells derived from embryonic neurepithelium. Graph MPATH:566 biolink:PathologicalEntityMixin tumors of the meninges tumors of the meninges Graph MPATH:567 biolink:PathologicalEntityMixin pilocytic astrocytoma Glial cell derived tumor composed of bipolar cells with long `hairlike` GFAP-positive processes. (M9421/1). Graph cystic cerebellar astrocytoma MPATH:568 biolink:PathologicalEntityMixin mixed glioma Mixed tumor containing astrocytes within an oligodendroglioma or vice versa. In some cases both components may be neoplastic. (M-9382/3). Graph MPATH:570 biolink:PathologicalEntityMixin peripheral nervous system tumors Tumors of the peripheral nervous system. Graph MPATH:571 biolink:PathologicalEntityMixin pilomatricoma Tumor composed of the epithelial components of the most proximal (trichogenic) portion of the hair follicle associated with an aberrent hair cortex type of cornification (ghost cells or shadow cells). The most primitive cellular component consists of basophilic cells having scanty cytoplasm and nuclei that occasionally overlap to some extent. In humans mineralisation is common. Graph MPATH:572 biolink:PathologicalEntityMixin ossifying fibroma Ossifying fibromas are benign tumors derived from pluripotential mesenchymal stem cells or osteoblasts. Occur spontaneously or in response to radiation. Preferentially located in mandible, maxilla and caudal spine. Composed of a characteristically regular trabecular bone pattern embedded in a fibrous stroma. Proliferating component consists of spindle cells which give rise to cuboidal osteoblasts to form rounded bodies or trabeculae. Bone trabeculae resemble the alphabet soup shapes characteristic of fibrous dysplasia in humans. In contrast to fibrous dysplasia the bone trabeculae of ossifying fibroma are mostly lamellar and ringed by active osteoblasts. Graph MPATH:573 biolink:PathologicalEntityMixin inverted transitional cell papilloma Pre-malignant lesion of transitional cells, papillomatous form, in which proliferating epithelium is invaginated beneath the surface. Graph MPATH:575 biolink:PathologicalEntityMixin basaloid follicular neoplasms This is a new diagnostic term that the MMHC pathology panel felt best described a diagnostically challenging set of tumors that share the feature of being compose of basaloid cells showing follicular differentiation to some extent. These tumors are common in GEM involving the hedgehog signaling pathway and frequently have more than one of the histologic patterns listed below. The designation of benign and malignant has been excluded from the primary diagnosis purposely, as this is frequently difficult to determine in these characteristically well circumscribed tumors. The presence of a disorganized (non-palisaded) sheet-like growth pattern, tumor necrosis, or numerous mitoses are felt to represent malignant transformation. Graph MPATH:576 biolink:PathologicalEntityMixin trichofolliculoma Basaloid neoplasm with numerous mature hair follicles and hair formation. Graph MPATH:577 biolink:PathologicalEntityMixin spiradenoma Cellular neoplasm with well formed palisades of basaloid cells adjacent to less basophilic smaller cells with occasional central deposition of amorphous eosinophilic material. These tumors share some features with cylindroma type tumors but have a less well developed jigsaw puzzle-like architecture and tend to be more cellular. Graph MPATH:578 biolink:PathologicalEntityMixin trichoblastoma Basaloid neoplasm with frequent primitive hair follicles. Graph MPATH:579 biolink:PathologicalEntityMixin ulcer Loss of epithelium and the basement membrane (full thickness). Cf Erosion. Graph MPATH:587 biolink:PathologicalEntityMixin Cribriform epididymal hyperplasia The lesion is characterized microscopically by epithelial cells with atypical hyperchromatic nuclei, vacuolization, intratubular lumina formation, infrequent apoptosis, and rare mitotic figures. In contrast to germ cells, the cells of CEH do not express alpha-fetoprotein, carcinoembryonic antigen, or S-100. Ultrastructurally, the cells are pleomorphic with stereocilia at their apical borders and within intratubular lumina, and are supported by a basement membrane. CEH does not appear to be a preneoplastic change. Graph MPATH:591 biolink:PathologicalEntityMixin fatty infiltration Accumulation of mature adipose tissue in a healing wound site or otherwise in response to tissue damage. Graph MPATH:594 biolink:PathologicalEntityMixin cystic hyperplasia Formation of multiple retention cysts from obstruction of ducts or glands by hyperplasia of the lining epithelium. Graph MPATH:595 biolink:PathologicalEntityMixin extramedullary hemopoiesis The formation of and development of blood cells outside the red pulp of the spleen. Composed of varying numbers of megakaryocytes as well as myeloid and erythroid precursors. Graph MPATH:60 biolink:PathologicalEntityMixin communication defect Failure of two cavities, voids or lumens to connect. Graph MPATH:600 biolink:PathologicalEntityMixin branching defect Aberrant branch or branching pattern of a branched structure such as the bronchus. Graph MPATH:602 biolink:PathologicalEntityMixin hyperplastic tissue An organ or a tissue with an abnormal increase in the number of cells as a consequence of cell proliferation. Graph MPATH:603 biolink:PathologicalEntityMixin pathological anatomical entity Anatomically located instance of pathological response or entity. Graph MPATH:605 biolink:PathologicalEntityMixin metaplastic tissue A tissue or group of cells in which there has been abnormal transformation of an fully differentiated adult cell or tissue of one kind into a differentiated tissue of another kind. Graph MPATH:607 biolink:PathologicalEntityMixin healing and repair structure Physical entity or structure associated with normal or abnormal tissue healing or repair following extrinsic or intrinsic damage. Graph MPATH:608 biolink:PathologicalEntityMixin abscess A circumscribed collection of purulent exudate frequently associated with swelling and other signs of inflammation. Graph MPATH:609 biolink:PathologicalEntityMixin empyema Pus in a body cavity; when used without qualification, refers specifically to pyothorax. Graph MPATH:61 biolink:PathologicalEntityMixin curvature defect Inappropriate curvature of a structure. Graph MPATH:610 biolink:PathologicalEntityMixin angiectasia Dilatation of a blood vessel or valve. Graph MPATH:613 biolink:PathologicalEntityMixin pigmentation Coloration, either normal or pathologic, of the skin or tissues resulting from a deposit of pigment. Graph MPATH:614 biolink:PathologicalEntityMixin concretion Solid material formed by aggregation of discrete units or particles. Graph MPATH:617 biolink:PathologicalEntityMixin focus of cellular alteration Focal lesions of hepatocytes characterised primarily by altered cytoplasmic tinctorial properties. Classified as basophilic, eosinophilic, clear cell or mixed type. Graph Areas of cellular alteration|Enzyme altered focus|Focus of altered hepatocytes (fah)|Hyperplastic focus|Phenotypically altered focus|Preneoplastic focus MPATH:618 biolink:PathologicalEntityMixin myeloid hyperplasia Hyperplasia of myeloid lineage, usually in the spleen. Graph MPATH:619 biolink:PathologicalEntityMixin truncoconal septal defect Septal defect lying between the aorta and pulmonary trunks caused by failure of the spiral septum to separate the truncus arteriosus. Graph MPATH:62 biolink:PathologicalEntityMixin cyst Formation of an epithelium bounded cavity not associated with neoplasia. Graph MPATH:620 biolink:PathologicalEntityMixin inter-atrial septal defect Incomplete closure of the inter-atrial septum due to failure of the primary or secondary septum. Graph MPATH:621 biolink:PathologicalEntityMixin inter-ventricular septal defect Failure of the inter-ventricular septum to completely close between the left and right ventricles. Graph MPATH:622 biolink:PathologicalEntityMixin steatosis Abnormal retention of lipids within a cell. Physically apparent as lipid within liposomes of parenchymal cells. Graph adipose degeneration|fatty change|fatty degeneration|lipidosis MPATH:623 biolink:PathologicalEntityMixin synechia An adhesion, usually between the iris and the cornea or the lens capsule. Graph MPATH:624 biolink:PathologicalEntityMixin involution Turning in of the edges of a structure. Graph MPATH:625 biolink:PathologicalEntityMixin avulsion Tearing away or separation of two structures or parts. Graph MPATH:626 biolink:PathologicalEntityMixin prolapse To sink down, said of an organ or other part. A sinking of an organ or other part, especially its appearance at a natural or artificial orifice. Graph MPATH:628 biolink:PathologicalEntityMixin pyogenic granuloma A small rounded mass of inflamed, highly vascular granulation tissue on the skin, frequently having an ulcerated surface. More likely a true neoplasm rather than a reactive lesion. Graph lobular capillary hemangioma MPATH:629 biolink:PathologicalEntityMixin cavernous hemangioma Deep cutaneous hemangioma with large dilated vascular spaces that manifests spontaneous involution. Graph MPATH:630 biolink:PathologicalEntityMixin karyomegaly Abnormally increased nuclear size. Graph MPATH:631 biolink:PathologicalEntityMixin hypertrophic tissue Tissue or cells undergoing hypertrophy, MPATH: 159. Graph MPATH:632 biolink:PathologicalEntityMixin hepatocytomegaly Increase in size of hepatocytes characterised by organelle hyperplasia and enlarged cellular volume. Graph Hepatocellular hypertrophy. MPATH:633 biolink:PathologicalEntityMixin cholelithiasis Presence of concretions in the gallbladder or bile ducts. Graph MPATH:635 biolink:PathologicalEntityMixin hydronephrosis Swelling of the kidneys when urine flow is obstructed in any of part of the urinary tract. Severe form of pyelectasia. Graph MPATH:637 biolink:PathologicalEntityMixin bursal cyst A retention cyst, resulting from an obstruction to the duct of a gland, within a bursa. Graph MPATH:639 biolink:PathologicalEntityMixin hydrocephalus Accumulation of water in the ventricles of the brain. Graph MPATH:641 biolink:PathologicalEntityMixin epidermal inclusion cyst Intradermal or subcutaneous cyst, the wall of which is stratified epithelium containing keratohyalin granules, surrounding a core of debris. Graph MPATH:642 biolink:PathologicalEntityMixin cholesterol deposition Intra or extracellular deposition of cholesterol. Graph MPATH:643 biolink:PathologicalEntityMixin serous exudate Non-cellular fluid that filters from the circulatory system and accumulates in lesions or areas of inflammation. Graph MPATH:644 biolink:PathologicalEntityMixin crystalloid formation Accumulation of chitinase-like protein. Graph MPATH:66 biolink:PathologicalEntityMixin dilatation Increase in the diameter of an orifice or tubular structure beyond its normal dimensions. Graph MPATH:67 biolink:PathologicalEntityMixin displacement and deformity Abnormal location, orientation, number, loss or non-specified deformity of a structure or tissue. Graph MPATH:68 biolink:PathologicalEntityMixin diverticulum A blind ended outpouching through the wall of a tubular organ or bounded cavity. Graph MPATH:685 biolink:PathologicalEntityMixin accessory organ Graph MPATH:686 biolink:PathologicalEntityMixin amputation Graph MPATH:687 biolink:PathologicalEntityMixin autoamputation Graph MPATH:691 biolink:PathologicalEntityMixin pustule Graph cutaneous abscess MPATH:694 biolink:PathologicalEntityMixin acidophilic anterior pituitary gland adenoma Graph MPATH:695 biolink:PathologicalEntityMixin spindle cell sarcoma Graph MPATH:696 biolink:PathologicalEntityMixin spindle cell hyperplasia Graph MPATH:698 biolink:PathologicalEntityMixin exostosis Graph osteophytes MPATH:699 biolink:PathologicalEntityMixin ankylosing exostosis Graph MPATH:70 biolink:PathologicalEntityMixin fistula An abnormal passage between two internal organs or leading from a cavity to the body surface. Graph MPATH:700 biolink:PathologicalEntityMixin ascites Graph MPATH:706 biolink:PathologicalEntityMixin cryptorchidism Graph MPATH:707 biolink:PathologicalEntityMixin angiolipoma Graph MPATH:708 biolink:PathologicalEntityMixin pyelectasia Distension of the renal pelvis by accumulated fluid or urine. Graph MPATH:709 biolink:PathologicalEntityMixin alveolar rhabdomyosarcoma Malignant tumor of striated muscle or pluripotential mesenchymal stem cells composed mainly of small round cells, with some partial skeletal muscle differentiation. Graph MPATH:710 biolink:PathologicalEntityMixin embryonal rhabdomyosarcoma Malignant mesenchymal tumor that morphologically and phenotypically resembles embryonal skeletal muscle. Graph Sarcoma Botryoides [Soft Tissues]|Embryonal Sarcoma|Malignant Rhabdomyoma|Myosarcoma|Rhabdopoietic Sarcoma MPATH:711 biolink:PathologicalEntityMixin situs ambiguus Graph MPATH:712 biolink:PathologicalEntityMixin heterotaxy Graph MPATH:713 biolink:PathologicalEntityMixin situs ambiguus totalis Graph situs inversus with dextrocardia MPATH:714 biolink:PathologicalEntityMixin situs inversus with levocardia Graph MPATH:716 biolink:PathologicalEntityMixin ciliary motility defect Graph primary ciliary dyskinesis MPATH:717 biolink:PathologicalEntityMixin sequestrum Graph MPATH:718 biolink:PathologicalEntityMixin pre-sacral teratoma Generally benign germ cell derived tumors of male or female containing derivatives from all three germ layers with differentiation in the malignant form being poor. Pre-sacral tumors located in the retrorectal space between the rectum and the sacrococcygeal part of the spine. Graph MPATH:719 biolink:PathologicalEntityMixin bronchiectasia Graph MPATH:720 biolink:PathologicalEntityMixin situs inversus Graph MPATH:721 biolink:PathologicalEntityMixin sacrococcygeal teratoma Generally benign germ cell derived tumors of male or female containing derivatives from all three germ layers with differentiation in the malignant form being poor. Sacrococcygeal tumors are located at the base of the coccyx. Graph MPATH:722 biolink:PathologicalEntityMixin rhabdomyoma Benign stromal tumors of the soft tissue with skeletal muscle differentiation. Graph MPATH:723 biolink:PathologicalEntityMixin fibromatosis Systemic manifestation of MPATH: 407. Graph Aggressive Fibromatosis|Desmoid Tumor|Musculoaponeurotic Fibromatosis|Plantar Fibromatosis (Ledderhose Disease) MPATH:724 biolink:PathologicalEntityMixin xanthoma Dermal, subcutaneous, or tendinous lesions characterized by accumulations of lipid-laden macrophages often rich in cholesterol. Graph MPATH:726 biolink:PathologicalEntityMixin hemosiderosis Graph MPATH:727 biolink:PathologicalEntityMixin hepatic hemosiderosis Graph MPATH:728 biolink:PathologicalEntityMixin pulmonary hemosiderosis Graph MPATH:729 biolink:PathologicalEntityMixin splenic melanosis Graph MPATH:730 biolink:PathologicalEntityMixin renal tubular concretion Graph MPATH:731 biolink:PathologicalEntityMixin Leydig cell hyperplasia Graph MPATH:732 biolink:PathologicalEntityMixin tracheal gland ectasia Graph MPATH:733 biolink:PathologicalEntityMixin mucometra A uterus distended with a fluid containing large quantities of mucin. Graph MPATH:735 biolink:PathologicalEntityMixin molar hypercementosis Thickening of the cementum layer of the molars. Graph MPATH:736 biolink:PathologicalEntityMixin ovarian follicular cyst Graph MPATH:739 biolink:PathologicalEntityMixin sub-retinal hemorrhage Extravascular blood between retina and choroid Graph MPATH:74 biolink:PathologicalEntityMixin hamartoma A focal malformation resembling a neoplasm which results from faulty development of an organ; composed of an abnormal mixture of tissue elements, or an abnormal proportion of a single element. Growth and location are usually normal for that tissue cf. Heterotopia/Choristoma MPATH:76/MPATH:477. Graph MPATH:740 biolink:PathologicalEntityMixin drusen Tiny yellow or white deposits of lamellar or amorphous extracellular material that build up between retina and retinal pigment epithelium. Graph MPATH:741 biolink:PathologicalEntityMixin splenomegaly An increase in size of the spleen. Graph MPATH:742 biolink:PathologicalEntityMixin intervertebral disk prolapse Rupture of the intervertebral disc, usually dorsally to compress the spinal cord, secondary to trauma. Graph MPATH:743 biolink:PathologicalEntityMixin hepatic centrolobular fatty metamorphosis Accumulation of clear large vacuoles in hepatocytes (most likely lipid pending frozen sections and oil red O or other lipid stains) around central veins. Graph MPATH:744 biolink:PathologicalEntityMixin pigmentary incontinence Release of melanin pigment in the dermis. Graph MPATH:747 biolink:PathologicalEntityMixin renal tubular amyloidosis Pink amorphous material (amyloid) deposited within the renal tubules. Graph MPATH:748 biolink:PathologicalEntityMixin recanalised thrombus An old organized thrombus that has been recanalized to permit blood flow. Graph MPATH:75 biolink:PathologicalEntityMixin hernia Protrusion of a loop or wall of an organ through an abnormal opening. Graph MPATH:750 biolink:PathologicalEntityMixin pulmonary adenomatosis Neoplastic proliferation of cuboidal cells lining alveoli most likely type II pneumocytes. Graph MPATH:751 biolink:PathologicalEntityMixin pigment dispersion Free pigment in anterior chamber/elsewhere in eye. Graph MPATH:752 biolink:PathologicalEntityMixin barbered loss of hair resulting from a behavioral abnormality in which the mouse, or more often other mice mice in the same box, remove hairs, initially vibrissae, from each other. Graph MPATH:753 biolink:PathologicalEntityMixin gastric forestomach papillomatous hyperplasia The forestomach of the mouse is lined by stratified squamous epithelia. At the limiting ridge there is hyperplasia to various degrees in which this epithelium proliferates to form raised areas on thin fibrovascular stalks. Graph MPATH:754 biolink:PathologicalEntityMixin splenic hemosiderosis Spleen contains foci of macrophages containing yellow brown pigment that is positive for iron using Prussian blue. Graph MPATH:755 biolink:PathologicalEntityMixin pulmonary interstitial mineralisation Small foci of mineralization within the interstitium between alveoli. Graph MPATH:757 biolink:PathologicalEntityMixin interstitial mineralization Foci of mineralization within the interstitium of a tissue. Graph MPATH:758 biolink:PathologicalEntityMixin renal interstitial mineralisation Small foci of mineralization within the interstitium between tubules. Graph MPATH:759 biolink:PathologicalEntityMixin pseudocyesis Appearance of clinical and/or subclinical signs and symptoms associated with pregnancy when the animal is not pregnant Graph false pregnancy MPATH:76 biolink:PathologicalEntityMixin heterotopia Congenital appearance of a body part or tissue or cell type in a region where it is not normally found ( topographical anomaly). Graph Ectopia MPATH:760 biolink:PathologicalEntityMixin ovarian bursal cyst Marked dilatation of the ovarian bursa. Graph MPATH:761 biolink:PathologicalEntityMixin muscle regeneration Linear palisaiding of nuclei within thin pale muscle fibers suggestive of repair. Graph MPATH:762 biolink:PathologicalEntityMixin thyroid follicle pleomorphism Thyroid gland follicles are filled with colloid but vary greatly in size. Graph MPATH:763 biolink:PathologicalEntityMixin sialocele Salivary gland duct occlusion resulting in massive enlargement forming a large cyst-like structure. Graph MPATH:764 biolink:PathologicalEntityMixin fracture A fracture is the (local) separation of a bone into two, or more, pieces under the action of stress. Graph MPATH:765 biolink:PathologicalEntityMixin fracture and healing Break in bone associated with exostoses. Graph MPATH:766 biolink:PathologicalEntityMixin intestinal amyloidosis The lamina propria is distended with amorphous hyalinized material interpreted to be amyloid protein. Graph MPATH:767 biolink:PathologicalEntityMixin Meckel's diverticulum A Meckel's diverticulum is a pouch on the wall of the lower part of the intestine that is present at birth. Graph MPATH:770 biolink:PathologicalEntityMixin abnormal organ size Abnormal organ dimensions or weight Graph MPATH:771 biolink:PathologicalEntityMixin abnormal organ length Abnormality of extent of the normal long axis Graph MPATH:772 biolink:PathologicalEntityMixin abnormal organ mass Abnormal mass of organ Graph MPATH:773 biolink:PathologicalEntityMixin abnormal intestine length Abnormal length of the intestine. Graph MPATH:776 biolink:PathologicalEntityMixin spermatocoele A spermatocoele is a cyst that contains spermatozoa. . Graph MPATH:777 biolink:PathologicalEntityMixin urelithiasis Formation of urinary concretions in any part of the kidney. Graph MPATH:778 biolink:PathologicalEntityMixin corpora amylacea https://doi.org/10.1038/srep41807 Graph MPATH:779 biolink:PathologicalEntityMixin uretolithiasis Formation or urinary concretions in the ureter. Graph MPATH:780 biolink:PathologicalEntityMixin pseudoxanthoma elasticum Pseudoxanthoma elasticum is a progressive disorder characterized by accumulated deposits of calcium and other minerals in elastic fibers. Graph MPATH:787 biolink:PathologicalEntityMixin intervertebral disk prolapse ventral Ventral prolapse of the intervertebral disk. Graph MPATH:788 biolink:PathologicalEntityMixin testicular torsion The testicle twisted around the vascular tract to constrict flow resulting in liquifactive necrosis of the affected testicle. Graph MPATH:79 biolink:PathologicalEntityMixin malposition Abnormal position or orientation of a structure insufficient to be called a heterotopia. Graph Misplacement MPATH:791 biolink:PathologicalEntityMixin cartilagenous embolism Occlusion of a vessel by a piece of dissected cartilage. Graph MPATH:792 biolink:PathologicalEntityMixin lymph node reticuloendothelial cell hyperplasia Proliferation of the reticuloendothelial cells in the medulla of the lymph node. Graph MPATH:794 biolink:PathologicalEntityMixin melena Digested blood in the lumen of the stomach or small intestine, indicative of hemorrhage. Graph MPATH:795 biolink:PathologicalEntityMixin psammoma body Round , often laminar, non-proteinaceous eosinophilic bodies representing calcium deposition. Graph MPATH:799 biolink:PathologicalEntityMixin scoliosis scoliosis is an abnormal curvature of the spine. The spine curves away from the middle or sideways. Graph MPATH:80 biolink:PathologicalEntityMixin obstruction and stenosis Occlusion ( partial or complete) of a lumen or space, internally by a space occupying mass or, in the case of stenosis, by local reduction in the diameter of a vessel, duct or the intestine. Graph MPATH:800 biolink:PathologicalEntityMixin intervertebral disk prolapse dorsal Dorsal prolapse of the intervertebral disk. Graph MPATH:801 biolink:PathologicalEntityMixin intervertebral disks prolapsed dorsally and ventrally Presence of dorsal and ventrally prolapsed disks in the same vertebral column. Graph MPATH:802 biolink:PathologicalEntityMixin rectal prolapse Eversion through the anus. Graph MPATH:803 biolink:PathologicalEntityMixin trabecular bone thickening Thickening of trabecular bone. Graph MPATH:804 biolink:PathologicalEntityMixin cavernous lymphangioma Large numbers of thin-walled dilated lymphatic channels situated in the dermis, subcutis or skeletal muscle. Graph MPATH:805 biolink:PathologicalEntityMixin cystic hygroma Variant of cavernous lymphangioma (MPATH:804) showing gross dilatation of lymphatic channels. Graph Cystic lymphangioma. MPATH:806 biolink:PathologicalEntityMixin lymphangioma circumscriptum Cutaneous grouped collection of thin-walled translucent vessels, which appear at birth or in early infancy and are commonest around the limb girdles. Graph MPATH:807 biolink:PathologicalEntityMixin hygroma Large cystic subcutaneous spaces usually found in the flexures, especially around the neck. Graph Cystic hygroma MPATH:808 biolink:PathologicalEntityMixin lymphedema Accumulation of interstitial fluid caused by blockage or failure of the lymphatic system. Graph Lymphoedema MPATH:809 biolink:PathologicalEntityMixin nuchal edema Edema of the posterior aspect of the fetal neck caused by an accumulation of fluid, usually lymph. Graph MPATH:81 biolink:PathologicalEntityMixin perforation Presence of a hole/channel through a normally imperforate structure often a membrane or septum. Graph MPATH:811 biolink:PathologicalEntityMixin epicardial mineralization Deposition of minerals in the epicardium. Graph MPATH:812 biolink:PathologicalEntityMixin blister A collection of fluid underneath the top layer of skin (epidermis). Graph MPATH:813 biolink:PathologicalEntityMixin epidermolysis bullosa lesions Lesions of a connective tissue disease causing blisters in the skin and mucosal membranes. Graph MPATH:814 biolink:PathologicalEntityMixin focal hepatic lipidosis Locally circumscribed regions of fatty change. Graph focal fatty change MPATH:815 biolink:PathologicalEntityMixin macrovesicular lipidosis subtype of steatosis with Hepatocytes containing a large well-defined single rounded vacuole within each cell, nucleus and cytoplasm displaced to the periphery, Graph macrovesicular steatosis MPATH:816 biolink:PathologicalEntityMixin microvesicular lipidosis Variant form of hepatic steatosis. Hepatocytes partially or completely filled with numerous small lipid vacuoles. Affected hepatocytes may have a foamy appearance.Small vacuoles do not normally displace the nucleus to the periphery in contrast to macrovesicular lipidosis. Graph microvesicular fatty change|microvesicular steatosis MPATH:819 biolink:PathologicalEntityMixin focal renal pelvic mineralisation. Graph MPATH:82 biolink:PathologicalEntityMixin persistent embryonic structure Persistence of an embryonic structure or tissue into the post-natal period in its normal location; (Chronological/temporal anomaly). Graph Embryonic rest. MPATH:820 biolink:PathologicalEntityMixin goitre Increase in size of the thyroid gland caused initially by uniform follicular epithelial hyperplasia generally in response to iodine deficiency. Graph goiter|hyperplastic goitre MPATH:821 biolink:PathologicalEntityMixin hypoplastic tissue Tissue showing smaller mass as a consequence of deficient proliferation or premature differentiation. Graph MPATH:822 biolink:PathologicalEntityMixin hypoplastic gut associated lymphoid tissue Reduced mass of GALT resulting form fewer cells. Graph MPATH:823 biolink:PathologicalEntityMixin myxofibroma A benign neoplasm characterized by mucous and fibroblastic tissues. Graph Fibromyxoma|fibroma myxomatodes. MPATH:824 biolink:PathologicalEntityMixin myofibroma A benign localized neoplasm arising from the subcutaneous tissues and skeletal muscle. It is characterized by the presence of myofibroblastic hyperchromatic spindle cells, hylanized stroma formation, calcification, necrosis, and a multinodular growth pattern. Graph Solitary Myofibromatosis MPATH:829 biolink:PathologicalEntityMixin true hermaphrodite possession of both ovary and testis due to primary sex determination defect Graph MPATH:83 biolink:PathologicalEntityMixin septation defect Any defect in the formation of septae not describable as perforation. Graph MPATH:832 biolink:PathologicalEntityMixin paraphimosis persistent retraction of the prepuce behind the glans penis Graph MPATH:834 biolink:PathologicalEntityMixin ovarian tubulostromal tumor non-malignant neoplasia of the ovary. Graph tubular adenoma MPATH:837 biolink:PathologicalEntityMixin hepatic mid-zonal fatty metamorphosis Fatty change in the mid-zonal region of the liver. Graph MPATH:838 biolink:PathologicalEntityMixin anaplastic carcinoma carcinoma with an absence of epithelial structural differentiation. Graph MPATH:839 biolink:PathologicalEntityMixin anaplastic hepatocellular carcinoma anaplastic carcinoma of the liver. Graph MPATH:84 biolink:PathologicalEntityMixin supernumerary structure Additional structure whether normally located or not. Graph MPATH:841 biolink:PathologicalEntityMixin anopthalmia Absence of eye. Graph MPATH:842 biolink:PathologicalEntityMixin coccygeal hemivertebrae abnormally shaped vertebral body often triangular as opposed to rectangular. Graph MPATH:843 biolink:PathologicalEntityMixin stasis Cessation of movement of a body fluid or liquid. Graph MPATH:844 biolink:PathologicalEntityMixin biliary stasis Cessation of the flow of bile due to bile duct blockage or overproduction. Graph MPATH:845 biolink:PathologicalEntityMixin partial abortion Evidence of residual placenta in utero without embryo. Graph MPATH:849 biolink:PathologicalEntityMixin anaplastic mammary adenocarcinoma poorly differentiated adenocarcinoma of the mammary gland Graph MPATH:850 biolink:PathologicalEntityMixin post-traumatic structural abnormality Morphological abnormality following trauma or related insult such as infection. Graph MPATH:851 biolink:PathologicalEntityMixin auricular deformation acquired dysmorphology of the external pinna following trauma or infection. Graph MPATH:858 biolink:PathologicalEntityMixin capillary hemangioma Benign proliferation of capillaries made up of closely packed aggregations of capillaries, usually of normal caliber, separated by scant connective stroma. Graph MPATH:86 biolink:PathologicalEntityMixin organ specific developmental defect Developmental defect characteristic of a particular organ or organ system which may be a recognised syndrome or a complex defect showing multiple manifestations. Graph MPATH:862 biolink:PathologicalEntityMixin flatus Accumulation or trapping of air Graph MPATH:866 biolink:PathologicalEntityMixin gastric adenomatous hyperplasia Thickening of the glandular epithelium Graph MPATH:868 biolink:PathologicalEntityMixin uterine ectasia Dilation of the uterus Graph hydrometra MPATH:869 biolink:PathologicalEntityMixin intussception Condition in which a part of the intestine has invaginated into another section of intestine, Graph MPATH:87 biolink:PathologicalEntityMixin germ cell defect Abnormal morphology, differentiation or location of primordial germ cells or their descendents. Not neoplastic. Graph MPATH:870 biolink:PathologicalEntityMixin junctional epidermolysis bullosa severe type of the disorder generally apparent at birth.Junctional epidermolysis bullosa involves defects in hemidesmosomes. t Graph MPATH:871 biolink:PathologicalEntityMixin spinal structural defects Structural defects of the bony and muscular components of the vertebrae. Graph MPATH:872 biolink:PathologicalEntityMixin kyphosis Abnormality of the kyphotic curvature of the spine. Graph MPATH:873 biolink:PathologicalEntityMixin micropthalmia Reduced size of the eye globe. Graph MPATH:874 biolink:PathologicalEntityMixin plasmacytosis Plasmacytosis is a hyperplastic condition in which there is an unusually large proportion of mature plasma cells in tissues, exudates, or blood. Graph MPATH:875 biolink:PathologicalEntityMixin cutaneous plasmacytosis cutaneous manifestation of plasmacytosis Graph MPATH:876 biolink:PathologicalEntityMixin systemic plasmacytosis systemic manifestation of plasmacytosis. Disseminated in the circulation. Graph MPATH:885 biolink:PathologicalEntityMixin metastatic tumor metastatic tumour of unspecified origin Graph MPATH:886 biolink:PathologicalEntityMixin pulmonary metastasis Metastatic tumour of unspecified origin in the lung. Graph MPATH:887 biolink:PathologicalEntityMixin lymphatic metastasis Metastatic tumor in the lymphatic vessels or lymph nodes of unspecified origin. Graph MPATH:888 biolink:PathologicalEntityMixin onychogryphosis Hypertrophy of the nail bed resulting in abnormally long, curved and thickened nails. Graph MPATH:889 biolink:PathologicalEntityMixin Hirano body intracellular aggregates of actin and actin-associated proteins first observed in neurons (nerve cells) by Asao Hirano. PMID: 21978358 Graph MPATH:89 biolink:PathologicalEntityMixin cardiovascular developmental defect Abnormal development of the heart or vascular tissue resulting in morphological abnormality. Graph MPATH:90 biolink:PathologicalEntityMixin aneurysm Localised dilation of an artery or heart chamber usually due to an acquired or congenital weakness of the wall of the artery or chamber. Graph MPATH:91 biolink:PathologicalEntityMixin arteriovenous anastomosis Formation of vessels between arterioles and venules bypassing capillary circulation. Graph Anastomosis arteriolovenularis|anastomosis arteriovenosa|arteriolovenular anastomosis MPATH:92 biolink:PathologicalEntityMixin cardiac defect Structural, organisational or growth related defects in cardiac development. Graph heart abnormalities MPATH:93 biolink:PathologicalEntityMixin cardiac septation defect Abnormality in the wall between the atria or ventricles, or defects in the truncoconal septum, of the heart; usually incomplete closure. Graph MPATH:94 biolink:PathologicalEntityMixin valve defect Malformation of the membranous folds of the heart that prevent reflux of fluid. Graph MPATH:95 biolink:PathologicalEntityMixin hypertrophic ventricle Thickening of the wall of one or both of the heart ventricles. Graph MPATH:96 biolink:PathologicalEntityMixin hypoplastic ventricle Reduction in cell number of one or both of the two lower chambers of the heart. Graph MPATH:97 biolink:PathologicalEntityMixin dissecting aneurysm Follows the presence of a hematoma in the wall of an artery Splitting of the media occurs, blood enters the split through a tear in the intima. Graph MPATH:98 biolink:PathologicalEntityMixin lymphangiectasis A stretching and widening of the lymphatic vessels. Graph Lymphectasia|telangiectasia lymphatica MPATH:99 biolink:PathologicalEntityMixin varices An enlarged and often tortuous vein. Graph NCIT:A11 biolink:subclass_of Graph NCIT:A14 biolink:subclass_of Graph NCIT:A16 biolink:subclass_of Graph NCIT:A3 biolink:subclass_of Graph NCIT:A7 biolink:physically_interacts_with Graph NCIT:Anatomic_Structure_Has_Location_Role biolink:location_of Graph NCIT:C16798 biolink:in_linkage_disequilibrium_with Graph NCIT:C172573 biolink:drug_regulatory_status_world_wide Graph NCIT:C26548 biolink:GeneProductMixin Graph NCIT:C2861 biolink:has_side_effect Graph NCIT:C37933 biolink:contraindicated_for Graph NCIT:C42677 biolink:reaction_direction Graph NCIT:C44185 biolink:p_value Graph NCIT:C54680 biolink:mechanism_of_action Graph NCIT:R100 biolink:located_in Graph NCIT:R101 biolink:affects Graph NCIT:R102 biolink:affects Graph NCIT:R113 biolink:affects Graph NCIT:R124 biolink:affects Graph NCIT:R130 biolink:participates_in Graph NCIT:R131 biolink:participates_in Graph NCIT:R133 biolink:affects Graph NCIT:R145 biolink:located_in Graph NCIT:R146 biolink:affects Graph NCIT:R150 biolink:affects Graph NCIT:R155 biolink:located_in Graph NCIT:R156 biolink:located_in Graph NCIT:R158 biolink:affects Graph NCIT:R160 biolink:affects Graph NCIT:R165 biolink:located_in Graph NCIT:R166 biolink:located_in Graph NCIT:R167 biolink:located_in Graph NCIT:R168 biolink:located_in Graph NCIT:R169 biolink:located_in Graph NCIT:R170 biolink:located_in Graph NCIT:R171 biolink:located_in Graph NCIT:R172 biolink:drug_regulatory_status_world_wide Graph NCIT:R173 biolink:affects Graph NCIT:R175 biolink:gene_associated_with_condition Graph NCIT:R176 biolink:condition_associated_with_gene Graph NCIT:R178 biolink:has_gene_product Graph NCIT:R23 biolink:affects Graph NCIT:R25 biolink:affects Graph NCIT:R27 biolink:part_of Graph NCIT:R29 biolink:produces Graph NCIT:R30 biolink:affects Graph NCIT:R31 biolink:has_output Graph NCIT:R36 biolink:subclass_of Graph NCIT:R37 biolink:participates_in Graph NCIT:R38 biolink:gene_associated_with_condition Graph NCIT:R39 biolink:biomarker_for Graph NCIT:R40 biolink:located_in Graph NCIT:R42 biolink:subclass_of Graph NCIT:R46 biolink:expressed_in Graph NCIT:R47 biolink:biomarker_for Graph NCIT:R48 biolink:gene_associated_with_condition Graph NCIT:R49 biolink:expressed_in Graph NCIT:R50 biolink:has_part Graph NCIT:R51 biolink:participates_in Graph NCIT:R52 biolink:capable_of Graph NCIT:R53 biolink:participates_in Graph NCIT:R72 biolink:affects Graph NCIT:R82 biolink:part_of Graph NCIT:R88 biolink:has_attribute Graph NCIT:R89 biolink:has_phenotype Graph NCIT:allele_has_abnormality biolink:causes Graph NCIT:allele_has_activity biolink:has_molecular_consequence Graph NCIT:biological_process_has_result_biological_process biolink:causes Graph NCIT:cdrh_parent_of biolink:superclass_of Graph NCIT:chemical_or_drug_has_physiologic_effect biolink:causes Graph NCIT:chemical_or_drug_initiates_biological_process biolink:causes Graph NCIT:chromosome_mapped_to_disease biolink:causes Graph NCIT:complex_has_physical_part biolink:has_part Graph NCIT:ctcae_5_parent_of biolink:superclass_of Graph NCIT:disease_has_molecular_abnormality biolink:has_biomarker Graph NCIT:disease_has_normal_tissue_origin biolink:causes Graph NCIT:disease_is_marked_by_gene biolink:has_biomarker Graph NCIT:disease_may_have_associated_disease biolink:related_to Graph NCIT:eo_disease_has_property_or_attribute biolink:has_attribute Graph NCIT:gene_encodes_gene_product biolink:has_gene_product Graph NCIT:gene_mapped_to_disease biolink:affects Graph NCIT:gene_product_has_chemical_classification biolink:subclass_of Graph NCIT:genetic_biomarker_related_to biolink:biomarker_for Graph NCIT:has_data_element biolink:has_attribute Graph NCIT:has_pharmaceutical_administration_method biolink:has_attribute Graph NCIT:has_pharmaceutical_basic_dose_form biolink:has_attribute Graph NCIT:has_pharmaceutical_intended_site biolink:has_attribute Graph NCIT:has_pharmaceutical_release_characteristics biolink:has_attribute Graph NCIT:has_pharmaceutical_state_of_matter biolink:has_attribute Graph NCIT:has_pharmaceutical_transformation biolink:has_attribute Graph NCIT:has_salt_form biolink:chemically_similar_to Graph NCIT:human_disease_maps_to_eo_disease biolink:related_to Graph NCIT:is_abnormal_cell_of_disease biolink:related_to Graph NCIT:is_component_of_chemotherapy_regimen biolink:part_of Graph NCIT:is_molecular_abnormality_of_disease biolink:biomarker_for Graph NCIT:is_qualified_by biolink:has_attribute Graph NCIT:is_related_to_endogenous_product biolink:related_to Graph NCIT:process_initiates_biological_process biolink:causes Graph NCIT:process_involves_gene biolink:has_participant Graph NCIT:qualifier_applies_to biolink:has_attribute Graph NCIT:regimen_has_accepted_use_for_disease biolink:treats Graph NCIT:role_has_domain biolink:has_attribute Graph NCIT:role_has_range biolink:has_attribute Graph NCIT:subset_includes_concept biolink:superclass_of Graph OBI:0000175 biolink:p_value p-value A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone. Graph OBI:0000293 biolink:has_participant has_specified_input A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of. Graph OBI:0000295 biolink:participates_in is_specified_input_of A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of. Graph OBI:0000299 biolink:has_output has_specified_output A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of. Graph OMIM:has_inheritance_type biolink:has_attribute Graph OMIM:has_manifestation biolink:superclass_of Graph OMIM:manifestation_of biolink:manifestation_of Graph PATO:correlates_with biolink:correlated_with Graph PATO:reciprocal_of biolink:related_to Graph PR:lacks_part biolink:lacks_part Graph PR:non-covalently_bound_to biolink:physically_interacts_with Graph RO:0000052 biolink:related_to inheres in a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence Graph RO:0000053 biolink:related_to has characteristic a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence Graph RO:0000056 biolink:participates_in participates in a relation between a continuant and a process, in which the continuant is somehow involved in the process Graph RO:0000057 biolink:has_participant has participant a relation between a process and a continuant, in which the continuant is somehow involved in the process Graph RO:0000086 biolink:has_attribute has quality a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence Graph RO:0000087 biolink:has_attribute has role a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence Graph RO:0001000 biolink:derives_from derives from a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity Graph RO:0001001 biolink:derives_into derives into a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity Graph RO:0001015 biolink:location_of location of a relation between two independent continuants, the location and the target, in which the target is entirely within the location Graph RO:0001019 biolink:has_part obsolete contains Graph RO:0001022 biolink:caused_by has allergic trigger A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity. Graph RO:0001025 biolink:located_in located in a relation between two independent continuants, the target and the location, in which the target is entirely within the location Graph RO:0002001 biolink:related_to aligned with Graph RO:0002002 biolink:related_to has_boundary a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity Graph RO:0002003 biolink:related_to electrically_synapsed_to A relation that holds between two neurons that are electrically coupled via gap junctions. Graph RO:0002007 biolink:part_of bounding layer of X outer_layer_of Y iff: . X :continuant that bearer_of some PATO:laminar . X part_of Y . exists Z :surface . X has_boundary Z . Z boundary_of Y has_boundary: http://purl.obolibrary.org/obo/RO_0002002 boundary_of: http://purl.obolibrary.org/obo/RO_0002000 Graph RO:0002008 biolink:related_to coincident with A relation that holds between two linear structures that are approximately parallel to each other for their entire length and where either the two structures are adjacent to each other or one is part of the other. Graph RO:0002082 biolink:temporally_related_to simultaneous with x simultaneous with y iff ω(x) = ω(y) and ω(α ) = ω(α), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point and '=' indicates the same instance in time. Graph RO:0002083 biolink:temporally_related_to before Graph RO:0002084 biolink:related_to during which ends Graph RO:0002087 biolink:preceded_by immediately preceded by Graph RO:0002090 biolink:precedes immediately precedes Graph RO:0002092 biolink:temporally_related_to happens during Graph RO:0002093 biolink:temporally_related_to ends during Graph RO:0002100 biolink:overlaps has soma location Relation between a neuron and an anatomical structure that its soma is part of. Graph RO:0002102 biolink:overlaps axon synapses in Relation between a neuron and some structure its axon forms (chemical) synapses in. Graph RO:0002104 biolink:has_plasma_membrane_part has plasma membrane part Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part. Graph RO:0002131 biolink:overlaps overlaps x overlaps y if and only if there exists some z such that x has part z and z part of y Graph RO:0002134 biolink:related_to innervates Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R. Graph RO:0002150 biolink:related_to continuous with X continuous_with Y if and only if X and Y share a fiat boundary. Graph RO:0002159 biolink:related_to serially homologous to Graph RO:0002160 biolink:in_taxon only in taxon x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z. Graph RO:0002162 biolink:in_taxon in taxon x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed. Graph RO:0002176 biolink:related_to connects c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system. Graph RO:0002177 biolink:related_to attached to part of a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b. Graph RO:0002178 biolink:related_to supplies Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy. Graph RO:0002179 biolink:related_to drains Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure. Graph RO:0002180 biolink:has_part has component w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. Graph RO:0002200 biolink:has_phenotype has phenotype A relationship that holds between a biological entity and a phenotype. Here a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). The subject of this relationship can be an organism (where the organism has the phenotype, i.e. the qualities inhere in parts of this organism), a genomic entity such as a gene or genotype (if modifications of the gene or the genotype causes the phenotype), or a condition such as a disease (such that if the condition inheres in an organism, then the organism has the phenotype). Graph RO:0002202 biolink:develops_from develops from x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y Graph RO:0002204 biolink:gene_product_of gene product of "definition ""x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from x""" Graph RO:0002205 biolink:has_gene_product has gene product x has gene product y if and only if x is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from y Graph RO:0002206 biolink:expressed_in expressed in x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process Graph RO:0002207 biolink:develops_from directly develops from Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y. Graph has developmental precursor RO:0002215 biolink:capable_of capable of A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. Graph RO:0002216 biolink:participates_in capable of part of c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p. Graph RO:0002219 biolink:coexists_with surrounded by x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x Graph RO:0002220 biolink:coexists_with adjacent to x adjacent to y if and only if x and y share a boundary. Graph RO:0002221 biolink:coexists_with surrounds inverse of surrounded by Graph RO:0002223 biolink:temporally_related_to starts inverse of starts with Graph RO:0002224 biolink:temporally_related_to starts with x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. Graph RO:0002225 biolink:develops_from develops from part of x develops from part of y if and only if there exists some z such that x develops from z and z is part of y Graph RO:0002226 biolink:develops_from develops in x develops_in y if x is located in y whilst x is developing Graph RO:0002229 biolink:temporally_related_to ends inverse of ends with Graph RO:0002230 biolink:temporally_related_to ends with x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. Graph RO:0002231 biolink:occurs_in has start location x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y Graph RO:0002232 biolink:occurs_in has end location x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y Graph RO:0002233 biolink:has_input has input p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p. Graph RO:0002234 biolink:has_output has output p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p. Graph RO:0002248 biolink:has_active_ingredient has active ingredient A relationship that holds between a substance and a chemical entity, if the chemical entity is part of the substance, and the chemical entity forms the biologically active component of the substance. Graph has active pharmaceutical ingredient|has active substance RO:0002249 biolink:is_active_ingredient_of active ingredient in inverse of has active ingredient Graph RO:0002255 biolink:contributes_to developmentally contributes to inverse of has developmental contribution from Graph RO:0002256 biolink:causes developmentally induced by t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T Graph RO:0002263 biolink:affects acts upstream of c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes. Graph RO:0002264 biolink:affects acts upstream of or within c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process. Graph affects RO:0002285 biolink:preceded_by developmentally replaces x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else Graph RO:0002292 biolink:expresses expresses y expresses x if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and x was transcribed from a gene as part of the gene expression process (iii) x is a mature gene product (protein or RNA), and x was translated or otherwise processed from a transcript that was transcribed as part of the gene expression process. Graph RO:0002296 biolink:has_output results in development of p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state. Graph RO:0002297 biolink:has_output results in formation of Graph RO:0002298 biolink:has_output results in morphogenesis of The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state. Graph RO:0002299 biolink:has_output results in maturation of The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity. Graph RO:0002302 biolink:treated_by is treated by substance Inverse of 'is substance that treats' Graph RO:0002303 biolink:located_in has habitat x 'has habitat' y if and only if: x is an organism, y is a habitat, and y can sustain and allow the growth of a population of xs. Graph RO:0002314 biolink:related_to inheres in part of q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w. Graph RO:0002315 biolink:causes results in acquisition of features of The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity Graph RO:0002322 biolink:related_to confers advantage in Graph RO:0002325 biolink:colocalizes_with colocalizes with a colocalizes_with b if and only if a is transiently or peripherally associated with b[GO]. Graph RO:0002326 biolink:contributes_to contributes to Graph RO:0002327 biolink:enables enables c enables p iff c is capable of p and c acts to execute p. Graph RO:0002328 biolink:related_to functionally related to A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities. Graph RO:0002331 biolink:actively_involved_in involved in c involved_in p if and only if c enables some process p', and p' is part of p Graph RO:0002332 biolink:related_to regulates levels of p regulates levels of c if p regulates some amount (PATO:0000070) of c Graph RO:0002333 biolink:enabled_by enabled by inverse of enables Graph RO:0002338 biolink:related_to has target start location This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination. Graph RO:0002339 biolink:related_to has target end location This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l. Graph RO:0002341 biolink:related_to results in transport along Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l Graph RO:0002342 biolink:related_to results in transport across Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m. Graph RO:0002343 biolink:affects results in growth of Graph RO:0002344 biolink:related_to results in transport to from or in Graph RO:0002348 biolink:related_to results in commitment to p 'results in commitment to' c if and only if p is a developmental process and c is a cell and p results in the state of c changing such that is can only develop into a single cell type. Graph RO:0002349 biolink:related_to results in determination of p 'results in determination of' c if and only if p is a developmental process and c is a cell and p results in the state of c changing to be determined. Once a cell becomes determined, it becomes committed to differentiate down a particular pathway regardless of its environment. Graph RO:0002350 biolink:part_of member of is member of is a mereological relation between a item and a collection. Graph RO:0002351 biolink:has_part has member has member is a mereological relation between a collection and an item. Graph RO:0002352 biolink:is_input_of input of inverse of has input Graph RO:0002353 biolink:is_output_of output of inverse of has output Graph RO:0002354 biolink:is_output_of formed as result of Graph RO:0002355 biolink:affects results in structural organization of A relationship between a process and an anatomical entity such that the process contributes to the act of creating the structural organization of the anatomical entity. Graph RO:0002356 biolink:related_to results in specification of The relationship linking a cell and its participation in a process that results in the fate of the cell being specified. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. Graph RO:0002371 biolink:related_to attached to a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a Graph RO:0002372 biolink:related_to has muscle origin m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to. Graph RO:0002373 biolink:related_to has muscle insertion m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone. Graph RO:0002374 biolink:related_to derived from ancestral fusion of x has_fused_element y iff: there exists some z : x has_part z, z homologous_to y, and y is a distinct element, the boundary between x and z is largely fiat Graph has fused element RO:0002376 biolink:part_of tributary of x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein. Graph RO:0002380 biolink:part_of branching part of x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y Graph RO:0002385 biolink:related_to has potential to developmentally contribute to x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y Graph RO:0002387 biolink:related_to has potential to develop into x has the potential to develop into y iff x develops into y or if x is capable of developing into y Graph RO:0002411 biolink:precedes causally upstream of p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q. Graph RO:0002412 biolink:precedes immediately causally upstream of p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q. Graph RO:0002432 biolink:active_in is active in c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure. Graph enables activity in RO:0002433 biolink:overlaps contributes to morphology of p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm. Graph RO:0002435 biolink:genetically_interacts_with genetically interacts with Graph RO:0002436 biolink:directly_physically_interacts_with molecularly interacts with An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other. Graph RO:0002448 biolink:regulates directly regulates activity of The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B. Graph molecularly controls RO:0002451 biolink:related_to transmitted by A relationship that holds between a disease and organism Graph RO:0002473 biolink:has_part composed primarily of x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y. Graph RO:0002488 biolink:temporally_related_to existence starts during x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y). Graph RO:0002489 biolink:temporally_related_to existence starts with x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y). Graph RO:0002492 biolink:temporally_related_to existence ends during x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y). Graph ceases_to_exist_during RO:0002493 biolink:temporally_related_to existence ends with x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y). Graph RO:0002494 biolink:related_to transformation of x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships Graph RO:0002495 biolink:related_to immediate transformation of x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t Graph RO:0002496 biolink:temporally_related_to existence starts during or after x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y). Graph RO:0002497 biolink:temporally_related_to existence ends during or before x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends. Graph RO:0002500 biolink:capable_of causal agent in process A relationship between a material entity and a process where the material entity has some causal role that influences the process Graph RO:0002503 biolink:actively_involved_in towards q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2 Graph RO:0002505 biolink:participates_in has intermediate p has intermediate c if and only if p has parts p1, p2 and p1 has output c, and p2 has input c Graph RO:0002507 biolink:causes determined by s determined by f if and only if s is a type of system, and f is a material entity that is part of s, such that f exerts a strong causal influence on the functioning of s, and the removal of f would cause the collapse of s. Graph RO:0002509 biolink:causes determined by part of s 'determined by part of' w if and only if there exists some f such that (1) s 'determined by' f and (2) f part_of w, or f=w. Graph RO:0002510 biolink:transcribed_from transcribed from x is transcribed from y if and only if x is synthesized from template y Graph RO:0002511 biolink:transcribed_to transcribed to inverse of transcribed from Graph RO:0002524 biolink:has_part has subsequence x has subsequence y iff all of the sequence parts of y are sequence parts of x Graph RO:0002551 biolink:has_part has skeleton A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision. Graph RO:0002558 biolink:has_evidence has evidence inverse of is evidence for Graph RO:0002565 biolink:has_participant results in movement of Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c Graph RO:0002568 biolink:related_to has muscle antagonist m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position. Graph RO:0002571 biolink:part_of lumen of x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull. Graph RO:0002572 biolink:part_of luminal space of s is luminal space of x iff s is lumen_of x and s is an immaterial entity Graph RO:0002573 biolink:related_to has modifier A relation that holds between an attribute or a qualifier and another attribute. Graph RO:0002576 biolink:part_of skeleton of inverse of has skeleton Graph RO:0002588 biolink:has_output results in assembly of Graph RO:0002590 biolink:has_input results in disassembly of Graph RO:0002591 biolink:affects results in remodeling of Graph RO:0002592 biolink:affects results in organization of p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c Graph RO:0002599 biolink:prevents capable of inhibiting or preventing pathological process Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a inhibits p. Graph RO:0002604 biolink:opposite_of is_opposite_of x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x). Graph RO:0002606 biolink:treats is substance that treats c is a substance that treats d if c is a material entity (such as a small molecule or compound) and d is a pathological process, phenotype or disease, and c is capable of some activity that negative regulates or decreases the magnitude of d. Graph RO:0002608 biolink:caused_by process has causal agent Inverse of 'causal agent in process' Graph RO:0002610 biolink:correlated_with correlated with A relationship that holds between two entities, where the entities exhibit a statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes. Graph RO:0003000 biolink:produces produces a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix. Graph RO:0003001 biolink:produced_by produced by a produced_by b iff some process that occurs_in b has_output a. Graph RO:0003301 biolink:model_of has role in modeling A relation between a biological, experimental, or computational artifact and an entity it is used to study, in virtue of its replicating or approximating features of the studied entity. Graph RO:0003303 biolink:causes causes condition A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal role for the condition. Graph RO:0003304 biolink:contributes_to contributes to condition A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some contributing role that influences the condition. Graph RO:0003307 biolink:ameliorates ameliorates condition A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the presence of the entity reduces or eliminates some or all aspects of the condition. Graph RO:0003309 biolink:exacerbates exacerbates condition A relationship between an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) and a condition (a phenotype or disease), where the presence of the entity worsens some or all aspects of the condition. Graph RO:0004001 biolink:causes has material basis in gain of function germline mutation in Graph RO:0004007 biolink:has_participant has primary input or output p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c. Graph RO:0004008 biolink:has_output has primary output p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c. Graph RO:0004009 biolink:has_input has primary input p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c. Graph RO:0004019 biolink:caused_by disease has basis in Graph RO:0004020 biolink:has_participant disease has basis in dysfunction of A relation that holds between the disease and a material entity where the physical basis of the disease is a disorder of that material entity that affects its function. Graph RO:0004021 biolink:has_participant disease has basis in disruption of A relation that holds between the disease and a process where the physical basis of the disease disrupts execution of a key biological process. Graph RO:0004022 biolink:has_phenotype disease has basis in feature A relation that holds between the disease and a feature (a phenotype or other disease) where the physical basis of the disease is the feature. Graph RO:0004024 biolink:disrupts disease disrupts A relationship between a disease and a process where the disease process disrupts the execution of the process. Graph RO:0004025 biolink:disrupts disease causes dysfunction of Graph RO:0004026 biolink:related_to disease has location A relationship between a disease and an anatomical entity where the disease has one or more features that are located in that entity. Graph RO:0004027 biolink:related_to disease has inflammation site A relationship between a disease and an anatomical entity where the disease is triggered by an inflammatory response to stimuli occurring in the anatomical entity Graph RO:0004028 biolink:caused_by realized in response to stimulus A relationship between a realizable entity R (e.g. function or disposition) and a material entity M where R is realized in response to a process that has an input stimulus of M. Graph RO:0004029 biolink:associated_with disease has feature A relationship between a disease and some feature of that disease, where the feature is either a phenotype or an isolated disease. Graph RO:0004032 biolink:acts_upstream_of_or_within_positive_effect acts upstream of or within, positive effect Graph RO:0004033 biolink:acts_upstream_of_or_within_negative_effect acts upstream of or within, negative effect Graph RO:0004034 biolink:acts_upstream_of_positive_effect acts upstream of, positive effect c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive Graph RO:0004035 biolink:acts_upstream_of_negative_effect acts upstream of, negative effect c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative Graph RO:0009001 biolink:related_to has substance added has substance added is a relation existing between a (physical) entity and a substance in which the entity has had the substance added to it at some point in time. Graph RO:0009004 biolink:related_to has consumer 'has consumer' is a relation between a material entity and an organism in which the former can normally be digested or otherwise absorbed by the latter without immediate or persistent ill effect. Graph RO:0009501 biolink:caused_by realized in response to r 'realized in response to' s iff, r is a realizable (e.g. a plant trait such as responsivity to drought), s is an environmental stimulus (a process), and s directly causes the realization of r. Graph triggered by process RO:0012003 biolink:affects acts on population of p acts on population of c iff c' is a collection, has members of type c, and p has participant c Graph RO:HOM0000000 biolink:similar_to in similarity relationship with Relation between biological objects that resemble or are related to each other sufficiently to warrant a comparison. Graph correspondence|resemblance|sameness|similar to RO:HOM0000001 biolink:homologous_to in homology relationship with Similarity that results from common evolutionary origin. Graph homologous to RO:HOM0000011 biolink:paralogous_to in paralogy relationship with Historical homology that involves genes that diverged after a duplication event. Graph paralogous to RO:HOM0000017 biolink:orthologous_to in orthology relationship with Historical homology that involves genes that diverged after a speciation event. Graph orthologous to RO:HOM0000018 biolink:xenologous_to in xenology relationship with Historical homology that is characterized by an interspecies (horizontal) transfer since the common ancestor. Graph xenologous to RO:has_participant biolink:has_participant Graph SNOMED:active_ingredient_of biolink:part_of Graph SNOMED:basis_of_strength_substance_of biolink:part_of Graph SNOMED:causative_agent_of biolink:causes Graph SNOMED:cause_of biolink:causes Graph SNOMED:component_of biolink:part_of Graph SNOMED:direct_substance_of biolink:part_of Graph SNOMED:during biolink:part_of Graph SNOMED:entire_anatomy_structure_of biolink:subclass_of Graph SNOMED:focus_of biolink:part_of Graph SNOMED:has_access biolink:has_attribute Graph SNOMED:has_associated_morphology biolink:related_to Graph SNOMED:has_associated_procedure biolink:related_to Graph SNOMED:has_basic_dose_form biolink:superclass_of Graph SNOMED:has_clinical_course biolink:has_attribute Graph SNOMED:has_component biolink:has_part Graph SNOMED:has_concentration_strength_denominator_unit biolink:has_unit Graph SNOMED:has_concentration_strength_numerator_unit biolink:has_unit Graph SNOMED:has_concentration_strength_numerator_value biolink:has_quantitative_value Graph SNOMED:has_count_of_base_of_active_ingredient biolink:has_attribute Graph SNOMED:has_definitional_manifestation biolink:manifestation_of Graph SNOMED:has_dependent biolink:part_of Graph SNOMED:has_direct_device biolink:participates_in Graph SNOMED:has_direct_morphology biolink:related_to Graph SNOMED:has_direct_procedure_site biolink:occurs_in Graph SNOMED:has_direct_site biolink:occurs_in Graph SNOMED:has_disposition biolink:related_to Graph SNOMED:has_dose_form biolink:subclass_of Graph SNOMED:has_dose_form_administration_method biolink:has_attribute Graph SNOMED:has_dose_form_intended_site biolink:has_route Graph SNOMED:has_dose_form_release_characteristic biolink:has_attribute Graph SNOMED:has_dose_form_transformation biolink:has_attribute Graph SNOMED:has_finding_context biolink:has_attribute Graph SNOMED:has_finding_informer biolink:has_attribute Graph SNOMED:has_finding_method biolink:has_input Graph SNOMED:has_finding_site biolink:located_in Graph SNOMED:has_indirect_device biolink:has_participant Graph SNOMED:has_indirect_morphology biolink:related_to Graph SNOMED:has_indirect_procedure_site biolink:located_in Graph SNOMED:has_inherent_attribute biolink:has_attribute Graph SNOMED:has_inherent_location biolink:located_in Graph SNOMED:has_intent biolink:has_attribute Graph SNOMED:has_interpretation biolink:has_attribute Graph SNOMED:has_laterality biolink:has_attribute Graph SNOMED:has_measurement_method biolink:has_attribute Graph SNOMED:has_method biolink:has_attribute Graph SNOMED:has_modification biolink:related_to Graph SNOMED:has_pathological_process biolink:affects Graph SNOMED:has_precondition biolink:has_input Graph SNOMED:has_presentation_strength_denominator_unit biolink:has_unit Graph SNOMED:has_presentation_strength_denominator_value biolink:has_quantitative_value Graph SNOMED:has_presentation_strength_numerator_unit biolink:has_unit Graph SNOMED:has_presentation_strength_numerator_value biolink:has_quantitative_value Graph SNOMED:has_priority biolink:has_attribute Graph SNOMED:has_procedure_context biolink:has_attribute Graph SNOMED:has_procedure_device biolink:has_participant Graph SNOMED:has_procedure_morphology biolink:related_to Graph SNOMED:has_procedure_site biolink:occurs_in Graph SNOMED:has_process_duration biolink:has_attribute Graph SNOMED:has_process_output biolink:produces Graph SNOMED:has_property biolink:has_attribute Graph SNOMED:has_realization biolink:causes Graph SNOMED:has_recipient_category biolink:has_participant Graph SNOMED:has_revision_status biolink:has_attribute Graph SNOMED:has_route_of_administration biolink:has_route Graph SNOMED:has_scale_type biolink:has_attribute Graph SNOMED:has_severity biolink:has_attribute Graph SNOMED:has_specimen biolink:has_attribute Graph SNOMED:has_specimen_source_identity biolink:has_input Graph SNOMED:has_specimen_source_morphology biolink:related_to Graph SNOMED:has_specimen_source_topography biolink:derives_from Graph SNOMED:has_specimen_substance biolink:has_input Graph SNOMED:has_state_of_matter biolink:has_attribute Graph SNOMED:has_subject_relationship_context biolink:has_attribute Graph SNOMED:has_surgical_approach biolink:has_attribute Graph SNOMED:has_technique biolink:has_attribute Graph SNOMED:has_temporal_context biolink:has_attribute Graph SNOMED:has_time_aspect biolink:has_attribute Graph SNOMED:has_unit_of_presentation biolink:has_unit Graph SNOMED:has_units biolink:has_attribute Graph SNOMED:inherent_location_of biolink:location_of Graph SNOMED:inheres_in biolink:related_to Graph SNOMED:is_interpreted_by biolink:related_to Graph SNOMED:occurs_before biolink:precedes Graph SNOMED:occurs_in biolink:occurs_in Graph SNOMED:part_anatomy_structure_of biolink:part_of Graph SNOMED:plays_role biolink:treats Graph SNOMED:precise_active_ingredient_of biolink:part_of Graph SNOMED:relative_to_part_of biolink:related_to Graph SNOMED:specimen_procedure_of biolink:produces Graph SNOMED:temporally_related_to biolink:temporally_related_to Graph SNOMED:uses_access_device biolink:has_input Graph SNOMED:uses_device biolink:has_input Graph SNOMED:uses_energy biolink:has_input Graph SNOMED:uses_substance biolink:has_input Graph SO:0000003 biolink:SequenceFeature Graph SO:0000054 biolink:SequenceFeature Graph SO:0000055 biolink:SequenceFeature Graph SO:0000056 biolink:SequenceFeature Graph SO:0000101 biolink:SequenceFeature Graph SO:0000105 biolink:SequenceFeature Graph SO:0000170 biolink:SequenceFeature Graph SO:0000210 biolink:SequenceFeature Graph SO:0000231 biolink:SequenceFeature Graph SO:0000232 biolink:SequenceFeature Graph SO:0000253 biolink:SequenceFeature Graph SO:0000274 biolink:SequenceFeature Graph SO:0000275 biolink:SequenceFeature Graph SO:0000286 biolink:SequenceFeature Graph SO:0000296 biolink:SequenceFeature Graph SO:0000325 biolink:SequenceFeature Graph SO:0000339 biolink:SequenceFeature Graph SO:0000370 biolink:SequenceFeature Graph SO:0000375 biolink:SequenceFeature Graph SO:0000407 biolink:SequenceFeature Graph SO:0000577 biolink:SequenceFeature Graph SO:0000605 biolink:SequenceFeature Graph SO:0000610 biolink:SequenceFeature Graph SO:0000644 biolink:SequenceFeature Graph SO:0000645 biolink:SequenceFeature Graph SO:0000652 biolink:SequenceFeature Graph SO:0000653 biolink:SequenceFeature Graph SO:0000871 biolink:SequenceFeature Graph SO:0001002 biolink:SequenceFeature Graph SO:0001019 biolink:SequenceFeature Graph SO:0001059 biolink:SequenceFeature Graph SO:0001217 biolink:SequenceFeature Graph SO:0001254 biolink:SequenceFeature Graph SO:0001263 biolink:SequenceFeature Graph SO:0001267 biolink:SequenceFeature Graph SO:0001268 biolink:SequenceFeature Graph SO:0001272 biolink:SequenceFeature Graph SO:0001533 biolink:SequenceFeature Graph SO:0001583 biolink:is_missense_variant_of Graph SO:0001589 biolink:is_frameshift_variant_of Graph SO:0001629 biolink:is_splice_site_variant_of Graph SO:0001637 biolink:SequenceFeature Graph SO:0001659 biolink:SequenceFeature Graph SO:0001789 biolink:SequenceFeature Graph SO:0001795 biolink:SequenceFeature Graph SO:0001796 biolink:SequenceFeature Graph SO:0001798 biolink:SequenceFeature Graph SO:0001799 biolink:SequenceFeature Graph SO:0001819 biolink:is_synonymous_variant_of Graph SO:0001843 biolink:SequenceFeature Graph SO:0001850 biolink:SequenceFeature Graph SO:0001855 biolink:SequenceFeature Graph SO:0001858 biolink:SequenceFeature Graph SO:0001859 biolink:SequenceFeature Graph SO:0001861 biolink:SequenceFeature Graph SO:0001871 biolink:SequenceFeature Graph SO:0001877 biolink:SequenceFeature Graph SO:0001905 biolink:SequenceFeature Graph SO:0001914 biolink:SequenceFeature Graph SO:0001927 biolink:SequenceFeature Graph SO:0001958 biolink:SequenceFeature Graph SO:0001984 biolink:SequenceFeature Graph SO:0001985 biolink:SequenceFeature Graph SO:0001997 biolink:SequenceFeature Graph SO:0002021 biolink:SequenceFeature Graph SO:0002025 biolink:SequenceFeature Graph SO:0002127 biolink:SequenceFeature Graph SO:0002140 biolink:SequenceFeature Graph SO:0002141 biolink:SequenceFeature Graph SO:0002157 biolink:SequenceFeature Graph SO:0002213 biolink:SequenceFeature Graph SO:1000008 biolink:SequenceFeature Graph SO:1000029 biolink:SequenceFeature Graph SO:1000045 biolink:SequenceFeature Graph SO:has_origin biolink:coexists_with Graph SO:similar_to biolink:similar_to Graph STATO:0000030 biolink:chi_squared_statistic Graph UBERON:anastomoses_with biolink:coexists_with Graph UBERON:anteriorly_connected_to biolink:coexists_with Graph UBERON:channel_for biolink:coexists_with Graph UBERON:channels_from biolink:coexists_with Graph UBERON:channels_into biolink:coexists_with Graph UBERON:conduit_for biolink:coexists_with Graph UBERON:distally_connected_to biolink:coexists_with Graph UBERON:existence_starts_and_ends_during biolink:coexists_with Graph UBERON:extends_fibers_into biolink:coexists_with Graph UBERON:filtered_through biolink:coexists_with Graph UBERON:in_central_side_of biolink:coexists_with Graph UBERON:in_innermost_side_of biolink:coexists_with Graph UBERON:in_outermost_side_of biolink:coexists_with Graph UBERON:indirectly_supplies biolink:coexists_with Graph UBERON:posteriorly_connected_to biolink:coexists_with Graph UBERON:protects biolink:coexists_with Graph UBERON:proximally_connected_to biolink:coexists_with Graph UBERON:sexually_homologous_to biolink:coexists_with Graph UBERON:subdivision_of biolink:part_of Graph UBERON:synapsed_by biolink:related_to Graph UPHENO:0000001 biolink:affects phenotype affects entity Graph XCO:0000000 biolink:ExposureEvent Graph OBO:core#connected_to biolink:related_to Graph OBO:core#distally_connected_to biolink:coexists_with Graph OBO:core#innervated_by biolink:related_to Graph OBO:core#subdivision_of biolink:coexists_with Graph OBO:doid#derives_from biolink:derives_from Graph OBO:doid#has_symptom biolink:has_phenotype Graph OBO:nbo#by_means biolink:actively_involved_in by_means Graph OBO:nbo#has_participant biolink:has_participant has_participant Graph OBO:nbo#in_response_to biolink:causes in_response_to Graph OBO:nbo#is_about biolink:related_to is_about Graph OBO:uberon/core#anastomoses_with biolink:coexists_with anastomoses with Graph OBO:uberon/core#anteriorly_connected_to biolink:coexists_with anteriorly connected to x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y. Graph OBO:uberon/core#channel_for biolink:coexists_with channel for Graph carries OBO:uberon/core#channels_from biolink:coexists_with channels_from Graph OBO:uberon/core#channels_into biolink:coexists_with channels_into Graph OBO:uberon/core#conduit_for biolink:coexists_with Graph OBO:uberon/core#distally_connected_to biolink:coexists_with distally connected to x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y. Graph OBO:uberon/core#extends_fibers_into biolink:coexists_with extends_fibers_into X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y Graph OBO:uberon/core#filtered_through biolink:coexists_with filtered through Relationship between a fluid and a material entity, where the fluid is the output of a realization of a filtration role that inheres in the material entity. Graph OBO:uberon/core#in_central_side_of biolink:located_in Graph OBO:uberon/core#in_innermost_side_of biolink:located_in in_innermost_side_of Graph OBO:uberon/core#in_outermost_side_of biolink:located_in in_outermost_side_of Graph OBO:uberon/core#indirectly_supplies biolink:coexists_with indirectly_supplies a indirectly_supplies s iff a has a branch and the branch supplies or indirectly supplies s. Graph OBO:uberon/core#layer_part_of biolink:part_of layer part of Graph OBO:uberon/core#posteriorly_connected_to biolink:coexists_with posteriorly connected to x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y. Graph OBO:uberon/core#protects biolink:related_to protects Graph OBO:uberon/core#proximally_connected_to biolink:coexists_with proximally connected to x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y. Graph OBO:uberon/core#sexually_homologous_to biolink:homologous_to sexually_homologous_to Graph OBO:uberon/core#site_of biolink:occurs_in site_of c site_of p if c is the bearer of a disposition that is realized by a process that has p as part. Graph capable_of_has_part OBO:uberon/core#subdivision_of biolink:part_of subdivision of Graph OBO:uberon/core#synapsed_by biolink:coexists_with Graph OBO:uberon/core#transitively_anteriorly_connected_to biolink:coexists_with transitively anteriorly connected to . Graph OBO:uberon/core#transitively_connected_to biolink:coexists_with transitively_connected to Graph OBO:uberon/core#transitively_distally_connected_to biolink:coexists_with transitively distally connected to . Graph OBO:uberon/core#transitively_proximally_connected_to biolink:coexists_with transitively proximally connected to . Graph OBO:uberon/core#trunk_part_of biolink:part_of trunk_part_of Graph dcterms:abstract biolink:summary Graph dcterms:contributor biolink:contributor contributor Graph dcterms:createdOn biolink:creation_date Graph dcterms:creator biolink:author Graph dcterms:format biolink:format Graph dcterms:isVersionOf biolink:version_of Graph dcterms:license biolink:license license Graph dcterms:publisher biolink:publisher Graph dcterms:rights biolink:rights Graph OBAN:association biolink:Association Graph OBAN:association_has_object_property biolink:has_attribute Graph OBAN:association_has_subject_property biolink:has_attribute Graph pav:createdWith biolink:created_with Graph pav:retrievedOn biolink:retrieved_on Graph SIO:000008 biolink:has_attribute Graph SIO:000628 biolink:mentions Graph SIO:000983 biolink:GeneToDiseaseOrPhenotypicFeatureAssociation Graph SIO:000993 biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation Graph SIO:001250 biolink:ChemicalToPathwayAssociation Graph SIO:001257 biolink:ChemicalGeneInteractionAssociation Graph SIO:010080 biolink:transcribed_to Graph SIO:010081 biolink:transcribed_from Graph SIO:010302 biolink:homologous_to Graph OIO:hasBroadSynonym biolink:broad_synonym has_broad_synonym An alternative label for a class or property which has a more general meaning than the preferred name/primary label. Graph OIO:hasDbXref biolink:close_match database_cross_reference Graph OIO:hasExactSynonym biolink:exact_synonym has_exact_synonym An alternative label for a class or property which has the exact same meaning than the preferred name/primary label. Graph OIO:hasNarrowSynonym biolink:narrow_synonym has_narrow_synonym An alternative label for a class or property which has a more specific meaning than the preferred name/primary label. Graph OIO:hasRelatedSynonym biolink:related_synonym has_related_synonym An alternative label for a class or property that has been used synonymously with the primary term name, but the usage is not strictly correct. Graph Orphanet:317343 biolink:causes Graph Orphanet:317344 biolink:causes Graph Orphanet:317346 biolink:causes Graph Orphanet:317348 biolink:actively_involved_in Graph Orphanet:317349 biolink:actively_involved_in Graph Orphanet:327767 biolink:actively_involved_in Graph Orphanet:410295 biolink:causes Graph Orphanet:410296 biolink:causes Graph Orphanet:465410 biolink:biomarker_for Graph Orphanet:C016 biolink:has_attribute Graph Orphanet:C017 biolink:has_attribute Graph rdf:Statement biolink:Association Graph rdfs:subClassOf biolink:subclass_of Graph rdfs:subPropertyOf biolink:subclass_of Graph owl:Axiom biolink:Association Graph owl:sameAs biolink:same_as Graph skos:altLabel biolink:synonym Graph skos:broadMatch biolink:broad_match Graph skos:closeMatch biolink:close_match Graph skos:exactMatch biolink:same_as Graph skos:member biolink:has_member Graph skos:narrowMatch biolink:narrow_match Graph skos:relatedMatch biolink:related_to Graph dcat:downloadURL biolink:distribution_download_url Graph foaf:topic biolink:has_topic Graph DATACOMMONS:DiseaseGeneAssociation biolink:GeneToDiseaseOrPhenotypicFeatureAssociation Graph DATACOMMONS:GenomeAnnotation biolink:GenomicSequenceLocalization Graph DATACOMMONS:MeSHTerm biolink:mesh_terms Graph DATACOMMONS:ProteinProteinInteraction biolink:PairwiseGeneToGeneInteraction Graph