Systematic Name Strain Descriptor Associated gene(s) Phenotypes DBS0350195 [act15]:acbA(Y72A) acbA decreased lipid binding DBS0350657 [csaA]:csaA csaA aberrant aggregation | increased calcium-independent cell-cell adhesion DBS0350059 mcln- mcln aberrant cellular response to fluid shear stress | increased growth rate | aberrant post-lysosomal vacuole exocytosis DBS0351382 myoB-/[act15]:GFP:myoB(1-921,1057-1111) myoB abolished protein localization to actin wave DBS0350826 pinA- pinA decreased growth rate | decreased mound size | decreased sporulation DBS0235412 1C7 gp130 decreased cell-substrate adhesion | delayed development | increased growth rate DBS0238601 5NT- 5nt delayed development of tipped mound | increased number of mound tips | increased number of early culminant tips DBS0351520 AK1334 DDB_G0271574 | nip7 decreased response to Gram-negative bacterium DBS0235584 CF45-1- cf45-1 increased mound size | increased glucose level | decreased mound size | decreased cell motility | increased cell-cell adhesion DBS0235585 CF50- cf50-1 | cf50-2 decreased response to Gram-negative bacterium | decreased response to Gram-positive bacterium | increased mound size | increased cell-cell adhesion | increased prespore gene expression | increased protein level | decreased protein secretion DBS0235594 CHE10 cbpC decreased slug migration | precocious aggregation | decreased mound size | decreased fruiting body size | delayed culmination DBS0235595 CHI2 cbpC increased slug migration DBS0235596 ChLim- ChLim increased growth rate | increased phagocytosis DBS0351197 D2B- D2B aberrant chemotaxis to cAMP DBS0235659 DD3-3- DD3-3 decreased gene expression | precocious aggregation DBS0236049 DDB_G0268012- DDB_G0268012 wild type DBS0236046 DDB_G0268158- DDB_G0268158 wild type DBS0236039 DDB_G0268678- DDB_G0268678 wild type DG1007 DDB_G0269232- DDB_G0269232 abolished culmination DBS0236025 DDB_G0270366- DDB_G0270366 wild type DBS0236026 DDB_G0270368- DDB_G0270368 wild type DBS0236036 DDB_G0270744- DDB_G0270744 wild type DBS0351081 DDB_G0272538- DDB_G0272538 delayed aggregation | increased cell-substrate adhesion LAS29 DDB_G0273201- DDB_G0273201 decreased socially cooperative development LAS8 DDB_G0273809- zplC-1 | zplC-2 decreased socially cooperative development LAS43 DDB_G0274429- DDB_G0274429 decreased socially cooperative development DBS0351079 DDB_G0274679- DDB_G0274679 delayed aggregation | increased cell-substrate adhesion | decreased cell motility DBS0236043 DDB_G0276221- fam21 wild type DBS0236042 DDB_G0276689- DDB_G0276689 wild type DBS0236041 DDB_G0277179- DDB_G0277179 wild type LAS26 DDB_G0277239- DDB_G0277239 decreased socially cooperative development DBS0236045 DDB_G0277575- DDB_G0277575 wild type DBS0236044 DDB_G0278315- DDB_G0278315 wild type LAS34 DDB_G0278585- DDB_G0278585 decreased socially cooperative development DBS0236038 DDB_G0279005- DDB_G0279005 wild type DBS0236032 DDB_G0279163- DDB_G0279163 wild type DBS0236033 DDB_G0279163- DDB_G0279163 wild type LAS70 DDB_G0279405- DDB_G0279405 decreased socially cooperative development DBS0236028 DDB_G0279609- DDB_G0279609 wild type DBS0236029 DDB_G0279609- DDB_G0279609 wild type LAS103 DDB_G0280089- DDB_G0280089 decreased socially cooperative development LAS54 DDB_G0280299- DDB_G0280299 decreased socially cooperative development DBS0236035 DDB_G0280481- DDB_G0280481 wild type DBS0351082 DDB_G0281485- DDB_G0281485 delayed aggregation | increased cell-substrate adhesion | decreased cell motility DBS0351080 DDB_G0281497- DDB_G0281497 delayed aggregation | increased cell-substrate adhesion | decreased cell motility DBS0236019 DDB_G0281735- DDB_G0281735 wild type DBS0236020 DDB_G0281735- DDB_G0281735 wild type DBS0351620 DDB_G0281735-/DDB_G0281737- DDB_G0281735 | DDB_G0281737 decreased response to Gram-negative bacterium | aberrant vegetative growth LAS92 DDB_G0283373- DDB_G0283373 decreased socially cooperative development LAS106 DDB_G0283595- DDB_G0283595 decreased socially cooperative development DBS0351085 DDB_G0284955- DDB_G0284955 delayed aggregation | increased cell-substrate adhesion | decreased cell motility LAS3 DDB_G0287153- DDB_G0287153 decreased socially cooperative development LAS10 DDB_G0288547- DDB_G0288547 decreased socially cooperative development LAS9 DDB_G0289789- DDB_G0289789 decreased socially cooperative development DBS0236027 DDB_G0290225- DDB_G0290225 wild type DBS0351086 DDB_G0290519- DDB_G0290519 delayed aggregation | increased cell-substrate adhesion | decreased cell motility LAS7 DDB_G0290685- DDB_G0290685 decreased socially cooperative development DG1003 DDB_G0291992- DDB_G0291992 aberrant late culminant morphology LAS39 DDB_G0292148- DDB_G0292148 decreased socially cooperative development DBS0236037 DDB_G0292186- DDB_G0292186 wild type DBS0350073 DDB_G0293074- DDB_G0293074 decreased spore germination | delayed aggregation DBS0351083 DDB_G0293098- DDB_G0293098 delayed aggregation | increased cell-substrate adhesion | decreased cell motility DBS0236023 DDB_G0293116- DDB_G0293116 wild type DBS0236024 DDB_G0293116- DDB_G0293116 wild type DBS0350516 DDB_G0293356- DDB_G0293356 decreased defense response to Gram-negative bacterium DBS0236030 DDB_G0293762- DDB_G0293762 wild type DG1039 DG1039- DDB_G0284037 aberrant fruiting body morphogenesis DG1040 DG1040- DDB_G0276029 aberrant fruiting body morphogenesis DG1041 DG1041- DDB_G0269126 aberrant fruiting body morphogenesis DG1054 DG1054- DDB_G0277719 aberrant fruiting body morphogenesis DG1060 DG1060- DDB_G0281953 aberrant fruiting body morphogenesis DG1062 DG1062- cdl1A aberrant fruiting body morphogenesis DG1074 DG1074- DDB_G0272108 aberrant fruiting body morphogenesis DG1080 DG1080- DDB_G0281559 aberrant fruiting body morphogenesis DG1091 DG1091- DG1091 decreased fruiting body size DG1098 DG1098- DG1098 decreased fruiting body size DG1104 DG1104- DDB_G0283535 abolished aggregation DG1106 DG1106- keaA abolished aggregation DG1110 DG1110- DDB_G0269128 aberrant fruiting body morphogenesis DG1112 DG1112- DG1112 decreased stalk width DG1113 DG1113- DG1113 increased stalk length DG1122 DG1122- DG1122 aberrant fruiting body morphogenesis DG1124 DG1124- DG1124 development arrests at loose mound stage DG2033 DG2033- DG2033 development arrests at mound stage DG2044 DG2044- DG2044 development arrests at loose mound stage DBS0266700 Dd5P1- Dd5P1 increased chemotaxis to cAMP | decreased phagocytosis DBS0266705 Dd5P1-/Dd5P2- Dd5P1 | Dd5P2 increased chemotaxis to cAMP DBS0266704 Dd5P1-/Dd5P3- Dd5P1 | Dd5P3 increased chemotaxis to cAMP DBS0235660 Dd5P2- Dd5P2 increased chemotaxis to cAMP | increased actin filament polymerization DBS0266703 Dd5P2-/Dd5P3- Dd5P2 | Dd5P3 wild type DBS0266702 Dd5P3- Dd5P3 wild type DBS0266692 Dd5P4- Dd5P4 increased protein localization | increased protein phosphorylation | increased contractile vacuole size | decreased defense response to Gram-negative bacterium | increased number of mound tips | aberrant contractile vacuole discharge | decreased growth rate | decreased phagocytosis | decreased engulfment during phagocytosis | aberrant endosome morphology | aberrant vacuole organization | decreased protein localization | increased cell motility | increased activation of GTPase activity DBS0266693 Dd5P4-/[act15]:Dd5P4 Dd5P4 wild type DBS0266719 Dd5P4-/[act15]:Dd5P4:GFP Dd5P4 wild type DBS0266695 Dd5P4-/[act15]:GAP5P4 Dd5P4 increased number of mound tips | decreased growth rate DBS0351414 Dd5P4-/[act15]:GFP:Dd5P4(D319G) Dd5P4 increased contractile vacuole size | aberrant contractile vacuole discharge | aberrant protein localization to contractile vacuole DBS0266720 Dd5P4-/[act15]:Hs-OCRL Dd5P4 decreased phagocytosis DBS0266721 Dd5P4-/[act15]:Hs-OCRL(D422A) Dd5P4 decreased phagocytosis DBS0266694 Dd5P4-/[act15]:cat5P4 Dd5P4 increased number of mound tips | decreased growth rate DBS0351050 DidioMp27- DidioMp27 decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis DBS0351049 DidioMp36- DidioMp36 decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis CW0391 FLAG-VwkA vwkA increased myosin II assembly | decreased growth rate | aberrant cytokinesis | development arrests at mound stage | aberrant hypotonic response | increased protein level DBS0236015 GEG04K11 (tmcB- in KAX3) tmcB decreased macrocyst size | aberrant macrocyst formation DBS0236017 GEG10K23 (tmcC- in KAX3) tmcC aberrant macrocyst formation CW0368 GFP-VwkA vwkA decreased growth rate | aberrant cytokinesis DBS0266872 GFP:pcna pcna wild type DBS0350102 GFP:pcp pcp aberrant contractile vacuole morphology | aberrant hypotonic response DBS0302615 GFP:phgA(1-274:283-438)/phgA- phgA aberrant hypotonic response DBS0302614 GFP:phgA/phgA- phgA wild type DBS0236084 GP138A-/GP138B-/GP138C-/GP138D- cfrA | cfrB | cfrC | cfrD decreased gene expression DBS0236085 GP138C- cfrC wild type DL118 HL216/HL261 gnt2 decreased migratory slug size | decreased calcium-independent cell-cell adhesion | decreased fruiting body size HL220 HL220 gnt2 abolished gene expression | aberrant spore coat morphology | decreased calcium-independent cell-cell adhesion HL241 HL241 alg9 aberrant protein modification HL260 HL260 gnt2 decreased calcium-independent cell-cell adhesion HMW404 HMW404 manA abolished gene expression | abolished catalytic activity | abolished aggregation DBS0350714 HMW437 manA wild type | abolished catalytic activity AP1 HSPC300- hspc300 aberrant cytokinesis AP2 HSPC300- hspc300 decreased actin filament polymerization | decreased cell motility | decreased vegetative cell size | decreased phototaxis | decreased pseudopodium size DBS0351312 HSPC300-/[act15]:abpB(129-295) abpB | hspc300 aberrant cellular process HTY506 HTY506 pkaR aberrant spore morphology | precocious sporulation | aberrant fruiting body morphogenesis | decreased actin phosphorylation | precocious development | decreased cAMP level | decreased sporulation HTY507 HTY507 rdeA precocious aggregation | decreased mound size | increased cAMP level | aberrant fruiting body morphogenesis DBS0236426 I6KA- I6KA aberrant cellular homeostasis | aberrant inositol phosphate metabolic process | increased growth rate DBS0236444 JH.D cbfA abolished gene expression | aberrant cellular metabolic process | decreased gene expression | increased gene expression | decreased growth rate | increased pinocytosis | increased vegetative cell size | decreased fruiting body size | decreased stalk width | abolished aggregation | increased phagocytosis DBS0236532 M2 manA abolished vegetative growth DBS0236535 M31 modA decreased catalytic activity | decreased secretion of lysosomal enzymes DBS0236840 R7 nosA development arrests at mound stage DBS0266873 RFP:pcna pcna wild type DBS0236917 SA219 dscA-1 | dscA-2 | dscC-1 | dscC-2 | dscD-1 | dscD-2 | dscE abolished gene expression SA31 SA31 dscA-1 | dscA-2 | dscC-1 | dscC-2 | dscD-1 | dscD-2 | dscE abolished gene expression | abolished stream development | aberrant microtubule cytoskeleton organization | decreased establishment of cell polarity DBS0264065 V00262 dagA abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264066 V00347 DDB_G0281917 abolished culmination DBS0264073 V10108 DDB_G0292162 abolished stream development | abolished slug migration | aberrant vegetative growth | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264075 V10113 yakA abolished stream development | abolished slug migration | aberrant vegetative growth | abolished oscillatory cAMP signaling | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264078 V10116 tipB aberrant aggregation | abolished slug migration | aberrant oscillatory cAMP signaling | abolished culmination DBS0264079 V10117 DDB_G0285083 aberrant slug migration | abolished culmination DBS0264081 V10119 DDB_G0292194 wild type DBS0264083 V10121 zntC wild type DBS0264087 V10125 DDB_G0293302 aberrant slug migration | aberrant oscillatory cAMP signaling DBS0264088 V10126 tipC aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0264089 V10127 DG1037 abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264098 V10136 DDB_G0293590 wild type | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0264099 V10137 yelA aberrant aggregation | abolished slug migration | aberrant culmination | aberrant oscillatory cAMP signaling DBS0264100 V10138 tipC wild type DBS0264106 V10144 comH aberrant aggregation | abolished slug migration | abolished culmination DBS0264108 V10146 yakA abolished stream development | abolished slug migration | aberrant vegetative growth | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264109 V10147 tipA aberrant aggregation | abolished slug migration | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination DBS0264112 V10150 swp1 wild type DBS0264116 V10155 DDB_G0282093 abolished stream development | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264118 V10157 usp12 aberrant culmination | aberrant slug migration | aberrant stream morphology | abolished culmination DBS0264125 V10164 comE aberrant vegetative growth | aberrant culmination | aberrant slug migration | abolished culmination DBS0264126 V10165 comD aberrant aggregation | abolished slug migration | aberrant culmination | aberrant oscillatory cAMP signaling DBS0264128 V10167 DG1098 wild type | aberrant oscillatory cAMP signaling DBS0264129 V10168 prsC wild type | aberrant slug migration DBS0264131 V10170 DDB_G0283015 aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination DBS0264135 V10174 DDB_G0288581 aberrant vegetative growth | aberrant culmination | aberrant slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264145 V10185 abcA5 wild type | aberrant vegetative growth | aberrant culmination | aberrant oscillatory cAMP signaling DBS0264150 V10190 yelA aberrant aggregation | abolished slug migration | aberrant culmination | aberrant oscillatory cAMP signaling DBS0264151 V10191 sfbA aberrant culmination | aberrant slug migration | abolished culmination DBS0264152 V10192 tipD aberrant aggregation | abolished slug migration | aberrant oscillatory cAMP signaling | abolished culmination DBS0264154 V10194 modA aberrant culmination | aberrant slug migration DBS0264155 V10195 migA aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0264157 V10197 yelA abolished slug migration | aberrant culmination | aberrant slug migration DBS0264158 V10198 splA aberrant aggregation | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264159 V10199 DG1037 abolished slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264160 V10200 DDB_G0289377 aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0264161 V10201 rgaA aberrant vegetative growth | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination DBS0264163 V10203 modA wild type | aberrant vegetative growth | aberrant culmination DBS0264164 V10204 DG1124 aberrant aggregation | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264166 V10206 wimA wild type DBS0264169 V10209 dcsA abolished culmination DBS0264170 V10210 mkpA abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264171 V10211 migA aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264172 V10212 tipC aberrant aggregation | abolished slug migration | aberrant vegetative growth | aberrant culmination | aberrant oscillatory cAMP signaling DBS0264173 V10213 DG1098 aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264175 V10215 cbfB wild type DBS0264176 V10216 DDB_G0292884 wild type | aberrant vegetative growth DBS0264180 V10220 potA wild type DBS0264181 V10221 tipD aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0264182 V10222 ctaA wild type DBS0264183 V10223 erkA aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264184 V10224 DG1091 aberrant oscillatory cAMP signaling DBS0264185 V10225 acrA aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0264186 V10226 ggtA aberrant vegetative growth | aberrant culmination | aberrant slug migration | abolished aggregation | abolished culmination DBS0264187 V10227 piaA abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264188 V10228 comG aberrant aggregation | abolished slug migration | aberrant vegetative growth | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination DBS0264189 V10229 dcsA aberrant oscillatory cAMP signaling | abolished culmination DBS0264190 V10230 ctrA aberrant aggregation | aberrant culmination | aberrant slug migration DBS0264193 V10233 piaA abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264195 V10235 DDB_G0285985 wild type DBS0264196 V10236 DDB_G0270872_ps aberrant stream morphology DBS0264197 V10237 DDB_G0278621 wild type DBS0264198 V10238 DDB_G0269128 aberrant culmination | aberrant slug migration DBS0264199 V10239 kif12 wild type | aberrant culmination DBS0264201 V10241 lvsB aberrant culmination DBS0264202 V10242 tagB aberrant aggregation | abolished slug migration | abolished culmination DBS0264204 V10244 gbfA aberrant culmination | aberrant slug migration DBS0264205 V10245 gefA abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264206 V10246 dicB aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264207 V10247 yelA aberrant aggregation | abolished slug migration | aberrant culmination | aberrant oscillatory cAMP signaling | abolished culmination DBS0264212 V10252 tagB aberrant aggregation | abolished slug migration | abolished culmination DBS0264216 V10256 DDB_G0293302 abolished slug migration | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264218 V10258 rdeA aberrant aggregation | abolished slug migration | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling | abolished culmination DBS0264220 V10260 gacT aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0264224 V10264 DDB_G0282787_RTE aberrant aggregation | wild type | abolished slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling | abolished culmination DBS0264225 V10265 lvsD aberrant vegetative growth | aberrant culmination | aberrant oscillatory cAMP signaling DBS0264227 V10267 DDB_G0292260_RTE aberrant aggregation | aberrant stream morphology DBS0264228 V10268 dhkA aberrant culmination | aberrant slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264229 V10269 helC wild type | aberrant culmination | aberrant slug migration | abolished culmination DBS0264230 V10270 mekA aberrant vegetative growth | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264231 V10271 lvsB abolished stream development | abolished slug migration | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264232 V10272 modA abolished stream development | abolished slug migration | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264233 V10273 DDB_G0283535 wild type | aberrant vegetative growth DBS0264234 V10274 DG1113 aberrant vegetative growth | aberrant culmination | aberrant oscillatory cAMP signaling DBS0264235 V10275 DG1122 abolished stream development | wild type | abolished slug migration | aberrant vegetative growth | aberrant stream morphology | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264236 V10276 DDB_G0270654 wild type DBS0264237 V10277 lvsE aberrant oscillatory cAMP signaling DBS0264238 V10278 modA aberrant aggregation | abolished slug migration | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination DBS0264240 V10280 mekA aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination DBS0264241 V10281 DDB_G0268266 aberrant slug migration | aberrant oscillatory cAMP signaling DBS0264242 V10282 phdA abolished slug migration | aberrant culmination | aberrant stream morphology DBS0264245 V10285 scaA abolished stream development | abolished slug migration | aberrant vegetative growth | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264246 V10286 amdA wild type | aberrant culmination DBS0264247 V10287 helC wild type | aberrant culmination | aberrant slug migration DBS0264251 V10300 DDB_G0278333 aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0264269 V10322 roco5 aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination DBS0264272 V10326 DG1113 wild type | aberrant oscillatory cAMP signaling DBS0264275 V10330 DDB_G0282121 wild type DBS0264278 V10342 DDB_G0279727 wild type DBS0264281 V10356 DDB_G0275747 aberrant slug migration DBS0264283 V10363 msh5 wild type DBS0264284 V10367 DDB_G0282463 aberrant vegetative growth | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination DBS0264287 V10431 kcnma1 wild type | aberrant culmination | aberrant slug migration DBS0264288 V10432 DDB_G0291103 wild type DBS0264290 V10435 gefL abolished slug migration | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0264292 V10438 DDB_G0275671 wild type DBS0264295 V10442 pks3 wild type DBS0264297 V10445 DDB_G0290835 aberrant slug migration DBS0264303 V10460 abcC9 aberrant slug migration DBS0264316 V10483 yod1 aberrant aggregation | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination DBS0264318 V10490 gefV aberrant culmination | aberrant oscillatory cAMP signaling DBS0264319 V10492 med23 aberrant culmination | aberrant oscillatory cAMP signaling DBS0264320 V10495 DDB_G0269128 wild type | aberrant culmination | aberrant slug migration DBS0264324 V10514 adprt3 aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264326 V10519 DDB_G0290575 wild type DBS0264330 V10529 cyp508B1 aberrant aggregation | abolished slug migration | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0264331 V10530 DDB_G0270344 wild type | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0264334 V10534 DDB_G0291812 wild type | aberrant culmination DBS0264335 V10535 DDB_G0277165 aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264337 V10537 gbpC abolished stream development | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264347 V10567 dagA abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264349 V10570 DDB_G0281115 wild type | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0264356 V10588 dhkC wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264373 V10633 gtaG abolished slug migration | aberrant culmination | aberrant slug migration | abolished culmination DBS0264377 V10642 fscD wild type DBS0264384 V10670 taf2 wild type DBS0264390 V10682 clcD abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264425 V11033 nfaA aberrant aggregation | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264432 V11040 DDB_G0274177 abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0264438 V11047 DDB_G0269296 wild type DBS0264439 V11048 xrcc4 wild type DBS0264444 V11053 dscA-1 | dscA-2 wild type | aberrant vegetative growth DBS0264446 V11055 ku80 aberrant vegetative growth | aberrant culmination DBS0264464 V11075 cinC wild type | aberrant culmination DBS0264480 V11092 cnrO wild type DBS0264489 V11105 DDB_G0270350_ps wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264512 V11128 DDB_G0278945 aberrant vegetative growth | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264575 V30069 DDB_G0284619 aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264607 V30110 alg9 wild type | aberrant vegetative growth | aberrant oscillatory cAMP signaling DBS0264630 V30133 DDB_G0272953 wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264634 V30137 DDB_G0289529 wild type DBS0264662 V30165 alg9 wild type | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264668 V30171 DDB_G0285261 wild type | aberrant vegetative growth | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264677 V30180 gpaF wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264684 V30188 DDB_G0287723 wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264687 V30191 DDB_G0288219 wild type | aberrant vegetative growth DBS0264700 V30213 act9 wild type | aberrant culmination DBS0264715 V30229 dhx35 wild type | aberrant oscillatory cAMP signaling DBS0264716 V30230 regA aberrant aggregation | abolished slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling | abolished culmination DBS0264731 V30245 DDB_G0279461 wild type | aberrant culmination DBS0264749 V30264 DDB_G0273651 wild type DBS0264752 V30267 DDB_G0283759 wild type DBS0264756 V30271 ncapGa wild type DBS0264763 V30278 tnlA wild type DBS0264765 V30280 ppt1 wild type DBS0264768 V30283 DDB_G0270872_ps wild type DBS0264770 V30285 DDB_G0293762 wild type | aberrant vegetative growth DBS0264773 V30288 DDB_G0293300 wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264777 V30292 glpD wild type DBS0264781 V30296 DDB_G0270212 wild type DBS0264785 V30303 pakE aberrant oscillatory cAMP signaling DBS0264823 V30341 frmB wild type | aberrant culmination | aberrant stream morphology DBS0264832 V30350 DDB_G0284059 wild type DBS0264835 V30353 DDB_G0282471 wild type DBS0264853 V30371 abpC aberrant aggregation | abolished slug migration | aberrant culmination | abolished culmination DBS0264905 V30427 DDB_G0291926 aberrant culmination | aberrant slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264910 V30432 malA wild type DBS0264922 V30446 DDB_G0269430 wild type DBS0264924 V30448 DDB_G0269680 wild type | aberrant oscillatory cAMP signaling DBS0264941 V30466 dtfA wild type | aberrant oscillatory cAMP signaling DBS0264992 V30522 DDB_G0288007 wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0264994 V30524 prmt5 aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination DBS0265002 V30532 lvsA wild type | abolished slug migration | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination DBS0265017 V30547 DDB_G0279105 wild type | aberrant vegetative growth | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0265029 V30561 DDB_G0277355 wild type | aberrant culmination DBS0265045 V30578 DDB_G0277165 aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0265049 V30582 DDB_G0291722 wild type DBS0265064 V30604 DDB_G0279461 abolished slug migration | aberrant culmination | aberrant slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0265066 V30606 adkB wild type DBS0265099 V30642 tipC aberrant aggregation | abolished slug migration | aberrant oscillatory cAMP signaling | abolished culmination DBS0265126 V30673 dicB aberrant aggregation | abolished slug migration | aberrant culmination | aberrant oscillatory cAMP signaling DBS0265140 V30688 DDB_G0279727 wild type | aberrant culmination DBS0265170 V30724 cnrK wild type DBS0265206 V30766 rhgA wild type DBS0265226 V30789 itpa wild type DBS0265231 V30794 tpsA wild type DBS0265247 V30814 adprt1B wild type DBS0265279 V30846 DDB_G0286091 wild type DBS0265286 V30853 DDB_G0292058 wild type DBS0265296 V30863 DDB_G0269128 wild type DBS0265302 V30869 DDB_G0292454 wild type | aberrant vegetative growth DBS0265303 V30870 gxcJJ wild type | aberrant oscillatory cAMP signaling DBS0265309 V30876 DDB_G0268248 wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0265311 V30879 exoc2 wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0265319 V30887 adcC wild type DBS0265339 V30912 DDB_G0283821 wild type | aberrant oscillatory cAMP signaling DBS0265348 V30921 snpC wild type | aberrant culmination DBS0265422 V30995 DDB_G0282959 wild type DBS0265466 V31043 DDB_G0275917 aberrant aggregation | wild type | aberrant vegetative growth | aberrant slug migration | abolished culmination DBS0265497 V31075 DDB_G0282985 wild type | abolished slug migration | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling | abolished aggregation DBS0265520 V31102 DDB_G0287865 wild type DBS0265529 V31111 vps13E wild type | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0265539 V31121 DDB_G0270912 wild type | aberrant vegetative growth | aberrant oscillatory cAMP signaling DBS0265567 V31151 DDB_G0275539 wild type | aberrant vegetative growth | abolished culmination DBS0265573 V31157 act9 wild type DBS0265588 V31173 ggtA aberrant vegetative growth | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0265662 V31255 psiN wild type | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0265688 V31281 DDB_G0286417 wild type | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0265701 V31294 DDB_G0268424 wild type DBS0265873 V31480 DDB_G0284177 aberrant culmination DBS0265890 V31501 DDB_G0282985 wild type | aberrant culmination | aberrant oscillatory cAMP signaling DBS0265908 V31523 tmem184C wild type | aberrant culmination DBS0265911 V31528 DDB_G0279945 aberrant culmination DBS0265938 V31568 rsc12 aberrant culmination DBS0265947 V31583 DDB_G0282943 wild type DBS0265992 V31640 DDB_G0274343 wild type DBS0266000 V31649 DDB_G0290383 wild type | aberrant culmination DBS0266021 V31670 DDB_G0281269 wild type DBS0266022 V31671 dhkA aberrant culmination | aberrant slug migration DBS0266036 V31685 tipC aberrant aggregation | wild type | abolished slug migration | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0266084 V31738 dcsA wild type | aberrant culmination | abolished culmination DBS0266088 V31742 dstA aberrant culmination | aberrant slug migration | abolished culmination DBS0266089 V31743 DDB_G0273459 aberrant aggregation | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0266098 V31752 oplah wild type | aberrant oscillatory cAMP signaling DBS0266149 V31807 gpt1 wild type | aberrant vegetative growth | abolished vegetative growth DBS0266153 V31811 gpt1 wild type | aberrant vegetative growth | aberrant culmination | aberrant oscillatory cAMP signaling DBS0266190 V31853 chlA aberrant aggregation | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0266195 V31858 DDB_G0286341 wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0266246 V31916 psiF wild type | aberrant vegetative growth | aberrant culmination | aberrant oscillatory cAMP signaling DBS0266249 V31919 DDB_G0276251 aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0266253 V31923 DDB_G0268314 wild type | aberrant culmination DBS0266258 V31928 DDB_G0268314 wild type DBS0266271 V31941 manA aberrant aggregation | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling DBS0266299 V31970 DDB_G0280581 wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0266309 V31982 DDB_G0286341 abolished stream development | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling DBS0266316 V31989 DDB_G0270342 abolished stream development | wild type | abolished slug migration | aberrant culmination | aberrant oscillatory cAMP signaling DBS0237041 VatMpr vatM increased protein localization to cytoplasm | decreased phagocytosis | decreased growth rate | aberrant regulation of intracellular pH DBS0237044 VatMpr/[act15]:vatM vatM wild type DBS0237042 VatMpr/[act15]:vatM:GFP vatM decreased growth rate DBS0237236 [AS]:[tet]:trrA trrA decreased growth rate | delayed development | abolished aggregation DBS0350570 [AS]PARP DDB_G0286613 | DDB_G0289141 | adprt1A | adprt1B | adprt2 | adprt3 | adprt4 | pARTf | pARTg decreased cell death | aberrant positive regulation of mitochondrial membrane potential DBS0350559 [AS]act15:adprt1A adprt1A development arrests at loose mound stage | decreased gene expression | decreased ATP level | increased mitochondrial fission DBS0351092 [AS]aif aif aberrant cellular homeostasis | aberrant regulation of mitochondrial membrane potential | aberrant mitochondrion morphology | decreased ATP level | increased gene expression | decreased gene expression | decreased growth rate | aberrant cell cycle | increased necrotic cell death | delayed development | aberrant response to oxidative stress | aberrant cell morphology | increased mitochondrial fission | aberrant mitochondrion organization DBS0304456 [AS]alrA/gcsA- alrA | gcsA aberrant cellular metabolic process | increased gene expression | decreased growth rate | mitotic G1 phase arrest DBS0237273 [AS]calA calA abolished cytokinesis DBS0350897 [AS]carA carA-1 | carA-2 abolished aggregation DBS0237222 [AS]cf60 cf60 increased mound size | decreased number of mounds DBS0237228 [AS]cfrA/[AS]cfrB cfrA | cfrB decreased sexual fusion DBS0237223 [AS]chcA chcA decreased pinocytosis | delayed hypotonic response | decreased number of vacuoles | decreased vegetative cell size | aberrant vacuole organization | abolished aggregation DBS0237224 [AS]cmfA cmfA abolished aggregation DBS0236982 [AS]csbA/csbB csbA | csbB decreased cell-cell adhesion DBS0237225 [AS]cupB cupB abolished aggregation DBS0350979 [AS]deeJ deeJ decreased pinocytosis | decreased phagocytosis | aberrant fruiting body morphogenesis DBS0237226 [AS]dia1 dia1 decreased gene expression | precocious aggregation DBS0351176 [AS]dscA dscA-1 | dscA-2 abolished stream development DBS0238235 [AS]dutA dutA wild type DBS0350560 [AS]ecmB:adprt1A adprt1A development arrests at slug stage DBS0350676 [AS]erkA erkA aberrant vegetative growth DBS0237229 [AS]gpaA gpaA wild type DBS0351057 [AS]gshB gshB increased slug migration HPF414 [AS]hspA hspA decreased growth rate | aberrant fruiting body morphogenesis | decreased defense response to bacterium DBS0351041 [AS]hspA/[AS]ndkC-1 hspA | ndkC-1 | ndkC-2 wild type DBS0238749 [AS]hspA/snfA hspA | snfA wild type DBS0252819 [AS]hssA hssA wild type DBS0351171 [AS]htrA htrA decreased growth rate | aberrant fruiting body morphogenesis DBS0237230 [AS]ino1 ino1 abolished vegetative growth DBS0304425 [AS]mppA1 mppA1 delayed development DBS0304424 [AS]mppB mppB increased gene expression DBS0236725 [AS]patA patA decreased growth rate DBS0237504 [AS]pikE pikE aberrant stalk morphogenesis | decreased growth rate DBS0237231 [AS]ppiA ppiA increased stalk length DBS0237232 [AS]proA proA wild type DBS0350355 [AS]proA-/proB-/lmpA- lmpA | proA | proB abolished sporulation | wild type DBS0351311 [AS]proA/abpB(129-295) abpB | proA aberrant cellular process DBS0236827 [AS]proA/proB- proA | proB decreased exocytosis | decreased pinocytosis | aberrant exocytosis | increased actin filament polymerization | development arrests at slug stage | aberrant cytokinesis | decreased cell motility | abolished vegetative growth | decreased secretion of lysosomal enzymes | increased phagocytosis DBS0238036 [AS]proA/proB-/[act15]:proA proA | proB wild type DBS0238037 [AS]proA/proB-/[act15]:proB proA | proB wild type DBS0238035 [AS]proA/proB-/[unk]:FLAG:proC proA | proB | proC wild type DBS0350334 [AS]proA/proB-/scrA- proA | proB | scrA decreased exocytosis | decreased pinocytosis | decreased secretion of lysosomal enzymes DBS0350117 [AS]ptcB ptcB decreased growth rate DBS0236851 [AS]rapA rapA decreased pinocytosis | aberrant osmosensory signaling pathway | decreased phagocytosis | abolished vegetative growth | increased actin phosphorylation | aberrant hyperosmotic response DBS0351303 [AS]rheb rheb decreased growth rate | increased macropinocytosis | increased phagocytosis DBS0350574 [AS]rps4 rps4 decreased spore germination | aberrant actin cytoskeleton organization | aberrant vegetative growth | decreased mound size | decreased spore size | aberrant fruiting body morphogenesis | decreased sporulation DBS0236904 [AS]rps4 mrps4 delayed aggregation | aberrant fruiting body morphogenesis DBS0237234 [AS]smlA smlA decreased fruiting body size DBS0238748 [AS]snfA snfA decreased number of mitochondria | decreased ATP level | increased growth rate | decreased fruiting body size | aberrant mitochondrion organization DBS0304498 [AS]sslA1 sslA1 decreased fruiting body size DBS0237235 [AS]tcp1 tcp1 decreased growth rate | development arrests at mound stage | aberrant fruiting body morphogenesis DBS0351302 [AS]tpp1 tpp1 aberrant cellular process | decreased growth rate | aberrant sorocarp development | increased macropinocytosis | increased phagocytosis DBS0351218 [AS]twm1 twm1 decreased growth rate DBS0350649 [AS]vatB vatB delayed aggregation | aberrant slug migration | aberrant response to chemical DBS0306101 [AS]vatP vatP decreased calcium ion import | decreased growth rate DBS0306102 [AS]vatP vatP decreased calcium ion import | decreased growth rate | delayed development DBS0237276 [OE]:GFP:gxcA gxcA abolished aggregation DBS0237279 [OE]:HA:rab21(Q66L) rab21 increased phagocytosis | aberrant cytoskeleton organization DBS0237280 [OE]:HA:rab21(T21N) rab21 decreased phagocytosis | aberrant actin filament organization DBS0237274 [OE]:chlim ChLim increased actin filament polymerization | decreased phagocytosis | decreased growth rate DBS0350519 [OE]:egeA egeA decreased protein level | abolished aggregation DBS0237275 [OE]:gbfA gbfA precocious prespore gene expression JH182 [OE]:gpaD gpaD aberrant fruiting body morphogenesis | decreased sporulation JH258 [OE]:gpaE gpaE precocious prestalk gene expression | precocious prespore gene expression | precocious development of tipped mound DBS0348921 [OE]:ipkA1 ipkA1 aberrant inositol phosphate metabolic process | decreased response to lithium | aberrant gene expression DBS0348922 [OE]:itpk1 itpk1 aberrant inositol phosphate metabolic process | decreased response to lithium | aberrant gene expression DBS0237281 [OE]:limF limF increased actin filament polymerization | increased phagocytosis DBS0237282 [OE]:pakC pakC decreased cell motility DBS0236962 [OE]:pdiA pdiA delayed aggregation DBS0237015 [OE]:pdiA pdiA aberrant development of tipped mound | abolished culmination | abolished slug development DBS0237283 [OE]:rasB(G12T) rasB aberrant cytokinesis DBS0302685 [OE]:sgcA(1-2000)(N1106A):GFP/gca-/sgcA- gcA | sgcA decreased chemotaxis rate DBS0302683 [OE]:sgcA(878-2843)(N1106A):GFP/gca-/sgcA- gcA | sgcA decreased chemotaxis rate DBS0302681 [OE]:sgcA(878-2843):GFP/sgcA- gcA | sgcA aberrant chemotaxis to cAMP | decreased chemotaxis rate DBS0302682 [OE]:sgcA(N1106A):GFP/gca-/sgcA- gcA | sgcA increased lateral pseudopodium formation | aberrant chemotaxis to cAMP | aberrant stream morphology | decreased chemotaxis rate DBS0302684 [OE]:sgcA:GFP/gca-/sgcA- gcA | sgcA increased lateral pseudopodium formation | decreased chemotaxis rate DBS0237284 [OE]GFP:gxcA(1-750:764-1217) gxcA development arrests at loose mound stage DBS0237285 [OE]GFP:gxcA(1-750:764-984) gxcA development arrests at loose mound stage DBS0266621 [OE]mipp1 mipp1 aberrant inositol phosphate metabolic process | aberrant gene expression | increased response to lithium DBS0237299 [RNAi]DDB_G0270366 DDB_G0270366 wild type DBS0237300 [RNAi]DDB_G0270368 DDB_G0270368 wild type DBS0237301 [RNAi]DDB_G0271700 DDB_G0271700 wild type DBS0237304 [RNAi]DDB_G0273449 DDB_G0273449 | DDB_G0273577 wild type DBS0237303 [RNAi]DDB_G0279609 DDB_G0279609 wild type DBS0237306 [RNAi]DDB_G0290063 DDB_G0290063 wild type DBS0237302 [RNAi]DDB_G0290225 DDB_G0290225 wild type DBS0237298 [RNAi]DDB_G0293116 DDB_G0293116 wild type DBS0237305 [RNAi]DDB_G0293762 DDB_G0293762 wild type DBS0237294 [RNAi]DidioMp05 DidioMp05 wild type DBS0350172 [RNAi]allC allC development arrests at loose mound stage | decreased protein level | decreased gene expression | decreased vegetative cell size | increased growth rate DBS0350070 [RNAi]canA canA aberrant sorus morphology | aberrant response to cation stress | increased defense response to Gram-negative bacterium | decreased fruiting body size | decreased stalk length DBS0350727 [RNAi]cepE cepE increased number of centrosomes | aberrant cell separation during cytokinesis | aberrant mitotic sister chromatid segregation DBS0235409 [RNAi]cnbA cnbA aberrant sorus morphology | decreased gene expression | aberrant response to cation stress | increased defense response to Gram-negative bacterium | aberrant stalk cell differentiation | decreased stalk length DBS0349787 [RNAi]ctnnA ctnnA abolished epithelium-like organization | abolished stalk development | aberrant protein secretion | abolished establishment of cell polarity | aberrant Golgi localization | aberrant centrosome localization | abolished culmination | aberrant protein localization DBS0349923 [RNAi]ctnnA/[act15]:GFP-mhcA ctnnA aberrant stalk morphogenesis | decreased epithelium-like organization | aberrant protein localization DBS0237537 [RNAi]enlA enlA decreased substrate adhesion-dependent cell spreading | decreased cell-substrate adhesion | aberrant cytokinesis DBS0237295 [RNAi]fimA fimA wild type DBS0349944 [RNAi]fttB fttB increased number of mound tips | aberrant cytokinesis | decreased growth rate | delayed development | decreased chemotaxis to cAMP | aberrant cytoskeleton organization DBS0237308 [RNAi]gmsA gmsA decreased sexual fusion DBS0237309 [RNAi]gsr gsr precocious culmination | decreased cell migration to prestalk region | precocious gene expression DBS0252820 [RNAi]hssA hssA wild type DBS0237307 [RNAi]kctd9 kctd9 wild type DBS0350940 [RNAi]kif6 kif6 aberrant mitotic spindle organization DBS0237310 [RNAi]lipA lipA wild type DBS0349871 [RNAi]lkb1 lkb1 abolished prespore cell differentiation | delayed aggregation | aberrant slug development | aberrant sorocarp development | aberrant response to osmotic stress | aberrant response to oxidative stress | aberrant regulation of protein kinase activity | increased prestalk cell differentiation | decreased sporulation DBS0350643 [RNAi]nse1 nse1 aberrant response to UV | aberrant stream morphology | decreased fruiting body size DBS0350644 [RNAi]nse4 nse4 decreased gene expression | aberrant response to UV | aberrant stream morphology | decreased fruiting body size DBS0237296 [RNAi]pks16 pks16 wild type DBS0237297 [RNAi]psiM psiM wild type DBS0237311 [RNAi]racF2 racF2 abolished vegetative growth DBS0237312 [RNAi]rasZ rasZ wild type DBS0350488 [RNAi]rmd1 rmd1 aberrant cell separation during cytokinesis DBS0238734 [RNAi]sdhA sdhA abolished aggregation | decreased phototaxis DBS0351295 [RNAi]sir2D sir2D decreased gene expression | delayed development DBS0351599 [RNAi]srtA srtA increased pre-miRNA processing DBS0304564 [RNAi]sun1 sun1 aberrant nucleus morphology | increased vegetative cell size DBS0349929 [RNAi]tacA tacA aberrant response to cation stress | increased gene expression | delayed development | aberrant fruiting body morphogenesis DBS0350046 [RNAi]tacc tacc aberrant response to abiotic stimulus | decreased protein level | decreased size of astral microtubules YLD53 [RNAi]thg1 thg1 decreased growth rate DBS0350794 [RNAi]tlp3 tlp3 decreased growth rate DBS0350795 [RNAi]tlp4 tlp4 decreased growth rate DBS0237313 [RNAi]tmcB tmcB aberrant macrocyst formation DBS0237314 [RNAi]tmcC tmcC aberrant macrocyst formation DBS0237315 [RNAi]trap1 trap1 decreased gene expression | delayed development DBS0237818 [RNAi]wipA wipA decreased actin filament polymerization at leading edge | delayed pseudopodium formation | decreased chemotaxis to cAMP | decreased filopodium formation DBS0350924 [TRE-Pmin]:6xHis:GFP:dhcA(1384-4725(K1975T)) dhcA aberrant molecular function DBS0350052 [TRE-Pmin]:arfA(Q71L):GFP arfA aberrant filopodium formation | aberrant cytokinesis DBS0350053 [TRE-Pmin]:arfA(T31N):GFP arfA wild type | increased defense response to Gram-negative bacterium DBS0351202 [act15]:6xHis:amd1:eYFP amd1 decreased gene expression | increased gene expression | aberrant vegetative growth | aberrant fruiting body morphogenesis | delayed development | mitotic G1 phase arrest DBS0351167 [act15]:6xHis:ei24:eYFP ei24 aberrant aggregation | increased chemotaxis to cAMP | aberrant cell cycle | increased cAMP level | increased sporulation DBS0350674 [act15]:6xHis:erkA erkA aberrant slug development DBS0351253 [act15]:6xHis:sesn:eYFP sesn aberrant aggregation | decreased protein level | increased gene expression | decreased growth rate | aberrant response to oxidative stress DBS0349845 [act15]:7xHis:myoK:Ty1 myoK aberrant cortical actin cytoskeleton organization | aberrant engulfment during phagocytosis | aberrant cell morphology DBS0237100 [act15]:CFP:racC(G15V) racC increased actin filament polymerization DBS0237101 [act15]:CFP:racC(T20N) racC decreased actin filament polymerization | aberrant cytokinesis | abolished positive chemotaxis DBS0350908 [act15]:DD:GFP:rab8A(N128I) rab8A increased contractile vacuole size | increased number of contractile vacuoles | abolished protein localization to contractile vacuole DBS0350909 [act15]:DD:GFP:rab8A(Q74L) rab8A aberrant contractile vacuole localization | increased number of contractile vacuoles | decreased contractile vacuole size DBS0266512 [act15]:DDB_G0272656 sigN4 wild type DBS0350566 [act15]:FLAG:Rab14(Q67L) rab14 increased lysosome size | increased post-lysosomal vacuole size | aberrant phagosome maturation | increased endosomal vesicle fusion DBS0350049 [act15]:FLAG:cycC cycC precocious development of tipped mound DBS0350321 [act15]:FLAG:hbx4 hbx4 aberrant aggregation | abolished gene expression | abolished slug migration | decreased growth rate | aberrant cytokinesis DBS0350322 [act15]:FLAG:hbx4/[act15]:cadA cadA | hbx4 wild type DBS0350325 [act15]:FLAG:hbx4/[ecmAO]:lacZ hbx4 decreased spore germination | increased prestalk gene expression | abolished prespore gene expression | increased prestalk cell differentiation DBS0351294 [act15]:FLAG:mybB mybB increased gene expression | precocious development DBS0238107 [act15]:FLAG:ppp4C ppp4c wild type DBS0238108 [act15]:FLAG:ppp4C(H113Q) ppp4c development arrests at mound stage | delayed development DBS0351488 [act15]:FLAG:rasC(Q62L) rasC abolished protein localization to plasma membrane | increased actin filament polymerization | decreased chemotaxis to cAMP DBS0351292 [act15]:FLAG:sir2A sir2A delayed development DBS0351293 [act15]:FLAG:sir2C sir2C delayed development DBS0351291 [act15]:FLAG:sir2D sir2D increased gene expression | precocious development DBS0237110 [act15]:GFP(S65T)-racG racG increased filopodium formation | decreased actin filament polymerization | decreased cell motility | increased phagocytosis DBS0304572 [act15]:GFP:abpD(1441-1736) abpD abolished protein localization to nuclear envelope DBS0304571 [act15]:GFP:abpD(1441-1738) abpD abolished protein localization to nuclear envelope DBS0304573 [act15]:GFP:abpD(1441-1738,1737P/A) abpD abolished protein localization to nuclear envelope DBS0237114 [act15]:GFP:abpE(413-481) abpE-1 | abpE-2 increased lateral pseudopodium formation DBS0237116 [act15]:GFP:act15 act15 abolished cytokinesis | decreased cell motility | aberrant cell morphology DBS0351483 [act15]:GFP:aqpB(1-208,219-294) aqpB decreased hypotonic response DBS0351097 [act15]:GFP:cbpG cbpG increased cell-substrate adhesion | increased vegetative cell size | decreased chemotaxis to cAMP | abolished aggregation DBS0350593 [act15]:GFP:cepL cepL decreased growth rate | decreased phagocytosis | increased vegetative cell size | increased cell-substrate adhesion | aberrant centrosome localization | decreased establishment of cell polarity DBS0350594 [act15]:GFP:cepL(1-1114) cepL increased number of centrosomes | decreased growth rate | aberrant vegetative growth | increased fruiting body size | decreased phagocytosis | increased cell-substrate adhesion | decreased chemotaxis rate | aberrant phototaxis DBS0350595 [act15]:GFP:cepL(1-763) cepL increased number of centrosomes | decreased growth rate | aberrant vegetative growth | increased fruiting body size | decreased phagocytosis | increased cell-substrate adhesion | decreased chemotaxis rate | aberrant phototaxis DBS0350596 [act15]:GFP:cepL(763-1114) cepL development arrests at loose mound stage | abolished establishment of cell polarity | delayed aggregation | decreased vegetative cell size | increased cell-substrate adhesion | decreased chemotaxis rate | increased growth rate | aberrant phototaxis | delayed gene expression DBS0350460 [act15]:GFP:docD docD increased actin filament polymerization | increased cell motility | increased pseudopodium formation DBS0350288 [act15]:GFP:forF(1-1087) forF decreased pinocytosis | decreased phagocytosis | decreased growth rate DBS0235662 [act15]:GFP:forH(1-425) forH abolished protein localization to pseudopodium DBS0350984 [act15]:GFP:frmB frmB decreased spore size | aberrant stalk development DBS0304973 [act15]:GFP:gefQ(173-651,818-1298) gefQ increased guanyl-nucleotide exchange factor activity DBS0304971 [act15]:GFP:gefQ(683-833) gefQ decreased guanyl-nucleotide exchange factor activity DBS0304972 [act15]:GFP:gefQ(910-1298) gefQ aberrant cytokinesis | aberrant phototaxis DBS0351254 [act15]:GFP:gflB gflB decreased substrate adhesion-dependent cell spreading | decreased actin filament polymerization | increased cell motility DBS0350422 [act15]:GFP:gpbB gpbB aberrant vegetative growth | delayed development DBS0350349 [act15]:GFP:gtaC(1-467:497-587) gtaC abolished protein localization to nucleus DBS0350351 [act15]:GFP:gtaC(229-587) gtaC abolished protein localization to cytoplasm DBS0350359 [act15]:GFP:gtaC(281-467:497-587) gtaC aberrant protein localization to cytoplasm DBS0350352 [act15]:GFP:gtaC(281-587) gtaC abolished protein localization to cytoplasm DBS0350360 [act15]:GFP:gtaC(346-467:497-587) gtaC aberrant protein localization to cytoplasm | aberrant protein localization to nucleus DBS0350353 [act15]:GFP:gtaC(346-587) gtaC abolished protein localization to cytoplasm DBS0350350 [act15]:GFP:gtaC(K469,470,494,496A/R468,471A) gtaC abolished protein localization to nucleus DBS0236070 [act15]:GFP:hcpA hcpA decreased growth rate | aberrant mitotic anaphase DBS0236071 [act15]:GFP:hcpB hcpB decreased growth rate DBS0351562 [act15]:GFP:impA1 impa1 decreased response to lithium DBS0237117 [act15]:GFP:krsA krsA decreased slug migration DBS0237118 [act15]:GFP:limE limE aberrant cytokinesis DBS0351530 [act15]:GFP:lis1 lis1 decreased phagocytosis | decreased chemotaxis to folate DBS0349983 [act15]:GFP:lmnB lmnB aberrant chromatin assembly DBS0350490 [act15]:GFP:mhcA(T1823D/T1833D/T2029D)/AX3 mhcA decreased growth rate | aberrant localization DBS0237120 [act15]:GFP:nek2 nek2 aberrant nucleus morphology | increased number of microtubule organizing center DBS0350852 [act15]:GFP:nkaP nkaP aberrant aggregation | decreased gene expression | increased gene expression | aberrant vegetative growth | increased chemotaxis rate DBS0237121 [act15]:GFP:numA(1-117:168-340) numA aberrant cytokinesis DBS0350338 [act15]:GFP:pakA pakA increased phagocytosis DBS0350337 [act15]:GFP:pakA(797-1197) pakA decreased phagocytosis | decreased cell motility DBS0237122 [act15]:GFP:pats1(2087-2351) pats1 aberrant cytokinesis DBS0237123 [act15]:GFP:phg2(1-245) phg2 decreased phagocytosis DBS0235442 [act15]:GFP:pldB pldB abolished aggregation DBS0237702 [act15]:GFP:rac1A rac1A increased filopodium formation | increased membrane ruffling | increased macropinocytosis | increased growth rate | increased cell motility DBS0351073 [act15]:GFP:rac1A(G12V) rac1A decreased growth rate | decreased phagocytosis | aberrant cytokinesis | decreased macropinocytosis | decreased cell motility | delayed development | aberrant actin filament organization | abolished filopodium formation DBS0351075 [act15]:GFP:rac1A(T17N) rac1A aberrant filopodium formation DBS0237703 [act15]:GFP:rac1B rac1B increased filopodium formation | increased membrane ruffling DBS0237704 [act15]:GFP:rac1C rac1C increased filopodium formation | increased membrane ruffling | increased growth rate | increased cell motility DBS0351074 [act15]:GFP:rac1C(G12V) rac1C decreased growth rate | decreased phagocytosis | aberrant cytokinesis | decreased macropinocytosis | decreased cell motility | delayed development | aberrant actin filament organization | abolished filopodium formation DBS0351076 [act15]:GFP:rac1C(T17N) rac1C aberrant filopodium formation DBS0237125 [act15]:GFP:racG(1-168):racH(164-200) racG | racH increased filopodium formation | decreased actin filament polymerization | decreased phagocytosis DBS0237127 [act15]:GFP:racH racH decreased pinocytosis | wild type | decreased phagocytosis | decreased growth rate | aberrant cytokinesis | aberrant cell morphology DBS0237128 [act15]:GFP:racH(1-163):racG(167-201) racG | racH decreased actin filament polymerization DBS0237130 [act15]:GFP:racH(M13V) racH increased actin filament polymerization | aberrant cytokinesis | aberrant cell morphology DBS0237132 [act15]:GFP:racH(T18N) racH aberrant cytokinesis | aberrant cell morphology DBS0237133 [act15]:GFP:racH:gemA(630-658) gemA | racH delayed cytokinesis DBS0238392 [act15]:GFP:rapA rapA increased cell-substrate adhesion DBS0238393 [act15]:GFP:rapA(G12V) rapA increased cell-substrate adhesion DBS0238394 [act15]:GFP:rapA(S17N) rapA decreased cell-substrate adhesion DBS0350112 [act15]:GFP:rheb(D60I) rheb increased phagocytosis DBS0350111 [act15]:GFP:rheb(Q64L) rheb decreased phagocytosis DBS0237134 [act15]:GFP:sbds sbds wild type DBS0237135 [act15]:GFP:sbds sbds wild type DBS0351177 [act15]:GFP:sey1 sey1 decreased defense response to Gram-negative bacterium | aberrant vacuole organization DBS0351178 [act15]:GFP:sey1(K154A) sey1 increased defense response to Gram-negative bacterium | aberrant catalytic activity | decreased protein localization | aberrant endoplasmic reticulum organization DBS0350715 [act15]:GFP:src1(2-646) src1 aberrant nuclear envelope morphology DBS0304563 [act15]:GFP:sun1(283-905) sun1 increased number of centrosomes | decreased protein localization to nuclear envelope | aberrant nuclear membrane organization | aberrant nucleus morphology | increased vegetative cell size | aberrant centrosome localization | aberrant mitotic sister chromatid segregation DBS0350441 [act15]:GFP:talA/mhcA-/talA- mhcA | talA aberrant protein localization DBS0350648 [act15]:HA:Rab14(N121I) rab14 decreased pinocytosis | decreased hypotonic response | aberrant contractile vacuole morphology DBS0350899 [act15]:HA:rab11(N126I) rab11A aberrant contractile vacuole organization | aberrant contractile vacuole morphology | increased phagocytosis DBS0350812 [act15]:HA:rab7A(Q67L) rab7A increased exocytosis DBS0350813 [act15]:HA:rab7A(T22N) rab7A decreased pinocytosis | increased secretion of lysosomal enzymes | decreased exocytosis | decreased phagocytosis | aberrant phagosome maturation | abolished macropinocytosis | abolished protein localization to phagocytic vesicle DBS0238111 [act15]:HA:smkA smkA delayed development | decreased fruiting body size | decreased establishment of cell polarity | decreased chemotaxis to cAMP DBS0350429 [act15]:RFP:abpE abpE-1 | abpE-2 delayed aggregation DBS0350867 [act15]:RFP:mtpn mtpn increased filopodium formation | decreased protein localization to cell cortex | aberrant actin filament organization | decreased pseudopodium size DBS0351228 [act15]:T7:rasG(G12T) rasG increased protein phosphorylation | decreased growth rate | decreased phagocytosis | increased cell-substrate adhesion | decreased filopodium formation DBS0351226 [act15]:YFP:iqgC iqgC decreased phagocytosis | decreased macropinocytosis DBS0350986 [act15]:YFP:myoC(G395A) myoC decreased pinocytosis | aberrant mitotic spindle organization | decreased phagocytosis DBS0237201 [act15]:YFP:myoE myoE decreased pinocytosis | increased phagocytosis DBS0237817 [act15]:YFP:wipA wipA increased filopodium formation | increased actin filament polymerization at leading edge DBS0237819 [act15]:YFP:wipA(K36A) wipA increased filopodium formation | increased actin filament polymerization at leading edge DBS0237821 [act15]:YFP:wipA(K93A/S95A) wipA increased filopodium formation | increased actin filament polymerization at leading edge DBS0237227 [act15]:[AS]dia2 dia2 aberrant extracellular cAMP signaling pathway | abolished aggregation | decreased cAMP level DBS0350673 [act15]:abpC:GFP abpC decreased cell motility DBS0304574 [act15]:abpD abpD abolished protein localization to nuclear envelope DBS0237096 [act15]:abpE abpE-1 | abpE-2 aberrant aggregation | increased lateral pseudopodium formation | decreased cell motility | delayed development | decreased fruiting body size DBS0349940 [act15]:acrA(1-731):YFP acrA aberrant spore coat morphology | decreased adenylate cyclase activity DBS0350292 [act15]:act15(Y144W) act15 aberrant binding DBS0350800 [act15]:adprt1A adprt1A increased gene expression | decreased gene expression | decreased ATP level | delayed aggregation | aberrant cell cycle | decreased growth rate | aberrant response to oxidative stress | increased mitochondrial fission | decreased cAMP level DBS0238086 [act15]:atg1 atg1 wild type DBS0238091 [act15]:atg1(1-628) atg1 wild type DBS0238088 [act15]:atg1(K36A) atg1 abolished macroautophagy | increased number of autophagosomes | aberrant cellular response to nitrogen starvation | abolished aggregation DBS0238090 [act15]:atg1(K36A/1-628) atg1 wild type DBS0350008 [act15]:bzpN:GFP bzpN decreased growth rate | abolished negative regulation of vegetative growth DBS0237097 [act15]:cak1:myc cak1-1 | cak1-2 aberrant DNA repair JK1 [act15]:carA carA-1 | carA-2 delayed aggregation DBS0252737 [act15]:carA(I104A) carA-1 | carA-2 decreased cAMP binding DBS0252732 [act15]:carA(I104C) carA-1 | carA-2 decreased protein kinase activation DBS0252740 [act15]:carA(I104D) carA-1 | carA-2 increased cAMP binding | delayed aggregation | aberrant oscillatory cAMP signaling | decreased protein kinase activation DBS0252744 [act15]:carA(I104E) carA-1 | carA-2 increased cAMP binding | delayed aggregation | aberrant oscillatory cAMP signaling DBS0252741 [act15]:carA(I104F) carA-1 | carA-2 increased cAMP binding | decreased protein kinase activation DBS0252738 [act15]:carA(I104G) carA-1 | carA-2 increased cAMP binding | decreased protein kinase activation DBS0252747 [act15]:carA(I104H) carA-1 | carA-2 development arrests at loose mound stage | increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation DBS0252749 [act15]:carA(I104K) carA-1 | carA-2 increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation | abolished aggregation DBS0252739 [act15]:carA(I104L) carA-1 | carA-2 wild type DBS0252742 [act15]:carA(I104M) carA-1 | carA-2 increased cAMP binding DBS0252746 [act15]:carA(I104N) carA-1 | carA-2 development arrests at loose mound stage | increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation DBS0252734 [act15]:carA(I104P) carA-1 | carA-2 decreased protein kinase activation DBS0252745 [act15]:carA(I104Q) carA-1 | carA-2 development arrests at loose mound stage | increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation DBS0252750 [act15]:carA(I104R) carA-1 | carA-2 development arrests at loose mound stage | increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation DBS0252743 [act15]:carA(I104S) carA-1 | carA-2 increased cAMP binding | aberrant oscillatory cAMP signaling | decreased protein kinase activation DBS0252735 [act15]:carA(I104T) carA-1 | carA-2 increased cAMP binding | aberrant oscillatory cAMP signaling DBS0252736 [act15]:carA(I104V) carA-1 | carA-2 wild type DBS0252733 [act15]:carA(I104W) carA-1 | carA-2 increased cAMP binding DBS0252748 [act15]:carA(I104Y) carA-1 | carA-2 development arrests at loose mound stage | increased cAMP binding | aberrant oscillatory cAMP signaling | decreased protein kinase activation DBS0351055 [act15]:catA catA decreased slug migration | decreased fruiting body size | decreased superoxide generation | decreased sporulation DBS0351588 [act15]:cdcD(E219K):RFP cdcD abolished catalytic activity DBS0350533 [act15]:cdcD(R154C):RFP cdcD decreased catalytic activity | aberrant protein modification | decreased phototaxis DBS0350532 [act15]:cdcD:RFP cdcD decreased protein level | increased catalytic activity | decreased growth rate DBS0237098 [act15]:cdk5(D144N) cdk5 decreased pinocytosis | increased mound size | aberrant protein level | delayed aggregation | decreased phagocytosis | decreased growth rate | decreased sporulation | decreased protein secretion DBS0237099 [act15]:cf60 cf60 increased number of mounds | aberrant mound size DBS0302445 [act15]:cfaD cfaD decreased growth rate | aberrant fruiting body morphogenesis DBS0350333 [act15]:cnrF:GFP cnrF aberrant regulation of GTPase activity DBS0302658 [act15]:cnrN:myc/smlA- cnrN | smlA decreased fruiting body size DBS0237102 [act15]:cofA cofA increased actin bundle formation | increased membrane ruffling | increased cell motility DBS0350583 [act15]:csaA csaA decreased cell-substrate adhesion | precocious aggregation | increased calcium-independent cell-cell adhesion DBS0350684 [act15]:csaA(1-488):gppA(469-544) csaA | gppA aberrant protein localization to cell surface DBS0350642 [act15]:cynA:GFP cynA aberrant cell motility | precocious aggregation | aberrant establishment or maintenance of cell polarity DBS0349864 [act15]:cyrA:GFP cyrA increased chemotaxis to cAMP DBS0237104 [act15]:dagA dagA wild type DBS0350978 [act15]:deeJ deeJ increased pinocytosis | increased growth rate | increased phagocytosis DBS0237105 [act15]:dgkA dgkA development arrests at loose mound stage | decreased chemotaxis rate | decreased myosin II assembly DBS0350946 [act15]:dhcA(1384-4725) dhcA aberrant microtubule cytoskeleton organization DBS0237106 [act15]:dhkC(394-661) dhkC development arrests at slug stage | increased slug migration DBS0235716 [act15]:dhkK dhkK precocious aggregation | development arrests at mound stage DBS0235705 [act15]:dhkK(D1125N) dhkK aberrant extracellular cAMP signaling pathway | delayed development DBS0235707 [act15]:dhkK(H825Q) dhkK precocious development | decreased fruiting body size DBS0235709 [act15]:dhkK(H825Q/D1125N) dhkK aberrant slug migration | delayed culmination DBS0237107 [act15]:dng1 dng1 aberrant extracellular cAMP signaling pathway | decreased growth rate | precocious aggregation DBS0351565 [act15]:eIF6 eIF6 aberrant cellular process DBS0350396 [act15]:eif2s1(S53A) eif2s1 aberrant spore morphology | decreased spore germination | decreased protein level DBS0350424 [act15]:eif2s1(S53A)/[bzpR]:lacZ eif2s1 abolished translation DBS0237562 [act15]:enlA(92-497) enlA decreased cell-substrate adhesion DBS0237108 [act15]:fbxA:FLAG fbxA decreased prespore cell differentiation DBS0350365 [act15]:fip(1163-2038) fip-1 | fip-2 aberrant prestalk O cell differentiation DBS0237109 [act15]:fps fps increased resistance to alendronic acid DBS0350012 [act15]:fps:GFP fps increased resistance to alendronic acid DBS0235979 [act15]:fszA:GFP fszA aberrant mitochondrion morphology DBS0351485 [act15]:fszB:GFP fszB decreased mitochondrial fusion | decreased mitochondrial fission DBS0349956 [act15]:fttB(K49E):GFP fttB aberrant cytoskeleton organization DBS0237601 [act15]:gbpD gbpD aberrant aggregation | decreased cell-cell adhesion | increased guanyl-nucleotide exchange factor activity | increased cell-substrate adhesion | decreased chemotaxis to cAMP | aberrant cell morphology | increased pseudopodium formation DBS0351056 [act15]:gcsA gcsA increased catalytic activity | decreased slug migration | aberrant gene expression | decreased fruiting body size | decreased superoxide generation | decreased sporulation DBS0237136 [act15]:gpaA gpaA increased stalk length | aberrant cytokinesis | aberrant fruiting body morphogenesis DBS0351058 [act15]:gpaB gpaB aberrant aggregation | abolished sporulation | development arrests at mound stage | increased cAMP level | aberrant actin filament polymerization | decreased establishment of cell polarity | aberrant protein localization to plasma membrane | increased prestalk cell differentiation DBS0350680 [act15]:gpaE gpaE abolished vegetative growth | decreased chemotaxis to folate DBS0237145 [act15]:gpaG gpaG aberrant fruiting body morphogenesis DBS0237146 [act15]:gpaH gpaH wild type DBS0350971 [act15]:gpaH/AX2 gpaH aberrant cytokinesis | decreased growth rate | aberrant spore germination | aberrant sorocarp development | increased cell-substrate adhesion | increased cell-cell adhesion DBS0237147 [act15]:gpaI(G38V):FLAG gpaI increased mound size | delayed aggregation | decreased number of mounds | aberrant fruiting body morphogenesis DBS0237148 [act15]:gpaI(Q196L):FLAG gpaI increased oscillatory cAMP signaling | decreased protein localization to plasma membrane | increased mound size | aberrant activation of adenylate cyclase activity | increased chemotaxis to cAMP | increased lateral pseudopodium formation | delayed aggregation | decreased number of mounds | increased actin filament polymerization | aberrant adaptation of signaling pathway | aberrant fruiting body morphogenesis | decreased establishment of cell polarity | decreased cGMP biosynthesis DBS0350079 [act15]:grlB grlB delayed aggregation DBS0237149 [act15]:grxA grxA decreased prespore gene expression | delayed culmination DBS0237151 [act15]:grxA(C21S) grxA wild type DBS0237152 [act15]:grxA/[act15]:lacZ grxA increased cell migration to prestalk region DBS0351054 [act15]:gshB gshB aberrant aggregation | abolished sporulation | increased gene expression | development arrests at mound stage | increased cAMP level | aberrant actin filament polymerization | decreased establishment of cell polarity DBS0351059 [act15]:gshB/[AS]gpaB gpaB | gshB aberrant stream morphology | decreased establishment of cell polarity | decreased sporulation DBS0237153 [act15]:gsr gsr increased cell migration to prestalk region | delayed culmination DBS0350989 [act15]:gst4 gst4 increased fruiting body size DBS0236152 [act15]:hcpA(1-161:218-225):GFP hcpA decreased growth rate DBS0236159 [act15]:hcpB(1-197:237-244):GFP hcpB decreased growth rate DBS0351607 [act15]:hsp101(K213A) hsp101 decreased cellular thermotolerance DBS0351608 [act15]:hsp101(K613A) hsp101 decreased cellular thermotolerance DBS0252821 [act15]:hssA hssA wild type DBS0351173 [act15]:htrA(S300A) htrA decreased growth rate | aberrant fruiting body morphogenesis DBS0351282 [act15]:htt:eYFP htt decreased gene expression | increased gene expression DBS0350397 [act15]:ifkA(881-1514(K1258G,F1320L)) ifkA decreased growth rate | increased protein level DBS0350037 [act15]:mekA(299-360) mekA decreased mound size DBS0350034 [act15]:mekA(K321A) mekA decreased mound size DBS0350033 [act15]:mekA(S444A/T448A) mekA decreased mound size DBS0237203 [act15]:mhkB:FLAG mhkB aberrant cytokinesis | decreased myosin II assembly DBS0350026 [act15]:mip1/[act15]:mekA:FLAG mekA | mip1-1 | mip1-2 aberrant protein localization to nucleus DBS0237157 [act15]:mkkA mkkA development arrests at mound stage | delayed development DBS0237158 [act15]:mkkA(K199A) mkkA precocious development | decreased sporulation DBS0237159 [act15]:mkkA{deltaWD40} mkkA development arrests at mound stage | aberrant fruiting body morphogenesis | delayed development DBS0350331 [act15]:mkpA:GFP:TAP mkpA increased resistance to cisplatin DBS0350332 [act15]:mkpB(C294V) mkpB-1 | mkpB-2 decreased migratory slug size | delayed prestalk gene expression | delayed prespore gene expression | aberrant sorocarp development | decreased resistance to cisplatin DBS0350330 [act15]:mkpB:GFP:TAP mkpB-1 | mkpB-2 increased resistance to cisplatin DBS0237160 [act15]:mtaA(1-813)/[dscB]tubA:GFP cepJ aberrant microtubule cytoskeleton organization DBS0237162 [act15]:myc-cdk8 cdk8 increased number of tip-organizers | precocious development of tipped mound DBS0350050 [act15]:myc:cdk8/[act15]:FLAG:cycC cdk8 | cycC precocious development of tipped mound DBS0266837 [act15]:myc:ptpC ptpC abolished protein localization to nucleus | aberrant hyperosmotic response | aberrant signal transduction DBS0350417 [act15]:myc:ptpC ptpC aberrant protein phosphorylation DBS0266839 [act15]:myc:ptpCΔ(C649S) ptpC aberrant protein localization to nucleus | increased protein tyrosine phosphorylation DBS0266838 [act15]:myc:ptpC(C649S) ptpC aberrant protein localization to nucleus | increased protein tyrosine phosphorylation DBS0238398 [act15]:myc:rapA rapA increased cell-substrate adhesion | decreased cell motility | aberrant cell morphology DBS0238396 [act15]:myc:rapA(G12V) rapA increased protein localization to cell cortex | delayed aggregation | increased cell-substrate adhesion | decreased cell motility | increased protein kinase activation DBS0238397 [act15]:myc:rapA(S17N) rapA decreased cell-substrate adhesion DBS0237167 [act15]:myc:rckA rckA delayed development DBS0237163 [act15]:myc:rckA(C551A) rckA delayed slug development | decreased chemotaxis rate DBS0237164 [act15]:myc:rckA(E510G) rckA delayed slug development | decreased chemotaxis rate DBS0237165 [act15]:myc:rckA(E510G/N511A) rckA delayed slug development | decreased chemotaxis rate DBS0237166 [act15]:myc:rckA(K867A) rckA precocious aggregation | delayed slug development | decreased chemotaxis rate DBS0350132 [act15]:myc:splB splB increased protein localization to nucleus | increased protein tyrosine phosphorylation DBS0351051 [act15]:myc:talA(2255-2492)/puf118(677-1036) puf118 | talA aberrant chemotaxis to cAMP | abolished protein localization to leading edge DBS0351359 [act15]:myoB myoB decreased pinocytosis | increased protein localization to cell cortex | delayed aggregation | decreased growth rate | decreased cell motility | delayed development | decreased fruiting body size | aberrant actin filament organization DBS0351037 [act15]:myoE(1-1005) myoE abolished phosphatidylinositol binding DBS0351036 [act15]:myoE(K859A/K863A/R868A/R869A):GFP myoE abolished phosphatidylinositol binding | abolished protein localization to plasma membrane DBS0349847 [act15]:myoK:Myc myoK decreased phagocytosis DBS0237175 [act15]:myoM myoM aberrant stream morphology | delayed development | increased pseudopodium size DBS0237178 [act15]:myoM-Mtail myoM decreased growth rate | aberrant hypotonic response | aberrant stream morphology | aberrant hyperosmotic response | delayed development | increased pseudopodium size DBS0237179 [act15]:myr:rckA rckA delayed development | decreased chemotaxis rate DBS0349860 [act15]:ndkC ndkC-1 | ndkC-2 decreased exocytosis | decreased pinocytosis | decreased phagocytosis | decreased growth rate | increased growth rate DBS0237180 [act15]:nramp1:GFP nramp1 increased defense response to Gram-negative bacterium | increased iron ion transport DBS0350858 [act15]:odc odc aberrant cellular metabolic process | aberrant cell cycle DBS0351201 [act15]:odc:eYFP odc decreased growth rate | delayed development DBS0237182 [act15]:pakA pakA wild type DBS0237183 [act15]:pakA(K394A) pakA development arrests at mound stage | delayed development DBS0237184 [act15]:pakA[CA] pakA abolished aggregation DBS0237185 [act15]:pakA[G+K] pakA wild type DBS0349855 [act15]:pakB(1-337:563-852) pakB decreased phagocytosis DBS0350901 [act15]:pdeE:YFP pdeE development arrests at loose mound stage | decreased oscillatory cAMP signaling DBS0351186 [act15]:phr2ab:GFP phr2aB aberrant cytokinesis | aberrant centrosome organization DBS0349903 [act15]:pisA pisA aberrant development of tipped mound | decreased slug migration | delayed aggregation | decreased fruiting body size DBS0349902 [act15]:pisA:GFP pisA decreased slug migration | increased gene expression | decreased gene expression | delayed aggregation | delayed development | decreased phototaxis DBS0350693 [act15]:pkaC pkaC precocious development DBS0237188 [act15]:pkaC(1-497) pkaC precocious development | decreased fruiting body size | decreased cAMP level DBS0235418 [act15]:pkaR pkaR aberrant response to abiotic stimulus DBS0237189 [act15]:pkaR(G135E/G261A) pkaR decreased protein tyrosine phosphorylation | decreased protein kinase activity | abolished cAMP binding | abolished oscillatory cAMP signaling | abolished aggregation DBS0350701 [act15]:pkaR(G135E/G261A)/AX3 pkaR decreased gene expression | abolished oscillatory cAMP signaling DBS0350609 [act15]:pkaR(S133T,G135E) pkaR decreased cAMP binding | decreased protein kinase activity | abolished oscillatory cAMP signaling | abolished aggregation DBS0350920 [act15]:pkcA pkcA increased catalytic activity | abolished aggregation DBS0235538 [act15]:pldB pldB increased catalytic activity | increased exocytosis | decreased actin filament polymerization | aberrant chemotaxis to cAMP | abolished aggregation | decreased sporulation DBS0349874 [act15]:psaA:GFP psaA aberrant sporulation DBS0351577 [act15]:psiA psiA decreased prespore gene expression | decreased stalk cell differentiation DBS0351579 [act15]:psiA/[cudA]:lacZ psiA aberrant prespore gene expression DBS0351580 [act15]:psiA/[ecmB]:lacZ psiA delayed prestalk gene expression DBS0350751 [act15]:pten(16-515):GFP pten abolished catalytic activity DBS0350750 [act15]:pten(186-515):GFP pten abolished catalytic activity DBS0350752 [act15]:pten(C124S):GFP pten abolished catalytic activity DBS0350753 [act15]:pten(G129E):GFP pten abolished catalytic activity DBS0350318 [act15]:rab11A:RFP rab11A aberrant contractile vacuole organization | decreased contractile vacuole size | abolished hypotonic response DBS0350951 [act15]:rac1B(Q61L) rac1B increased lateral pseudopodium formation | decreased chemotaxis to cAMP | aberrant actin filament organization DBS0350952 [act15]:rac1B(T17N) rac1B abolished establishment of cell polarity | delayed aggregation | aberrant actin filament organization | abolished chemotaxis to cAMP DBS0350469 [act15]:racE(G20V):GFP racE decreased actin filament polymerization | aberrant cytokinesis | decreased growth rate DBS0350584 [act15]:rapA(G12V) rapA abolished protein localization to nucleus | increased protein localization to cell cortex | aberrant nucleus morphology | decreased growth rate | aberrant cytokinesis | increased cell-substrate adhesion | abolished protein localization to centrosome | increased number of microtubule organizing center DBS0351497 [act15]:rasD(Q61L) rasD decreased protein kinase activation DBS0351496 [act15]:rasD(S17N) rasD increased protein kinase activation DBS0351212 [act15]:rasG(S17N) rasG aberrant activation of GTPase activity | decreased chemotaxis to cAMP DBS0350262 [act15]:rbg3 rbg3 increased lysosome size | decreased growth rate | delayed development DBS0237192 [act15]:rblA rblA delayed mitotic cell cycle DBS0350671 [act15]:regA(126-316):myc regA precocious sporulation DBS0349938 [act15]:rgaA rgaA decreased actin filament polymerization | aberrant cytokinesis | decreased cell motility DBS0351529 [act15]:rgbA(751-1072,1080-1284,1517-1846) rgbA aberrant macropinocytosis | abolished protein localization to macropinosome DBS0351528 [act15]:rgbA(751-1072,1121-1317,1505-1834) rgbA aberrant macropinocytosis | abolished protein localization to macropinosome DBS0351304 [act15]:rheb rheb decreased phagocytosis | decreased macropinocytosis | increased growth rate DBS0350294 [act15]:rheb:YFP rheb increased vegetative cell size DBS0350890 [act15]:rnp1A rnp1A increased resistance to nocodazole DBS0350575 [act15]:rps4 rps4 decreased spore germination | aberrant actin cytoskeleton organization | aberrant vegetative growth | decreased mound size | decreased spore size | aberrant fruiting body morphogenesis | decreased sporulation DBS0236915 [act15]:rzpA rzpA increased prestalk gene expression | decreased prespore gene expression | delayed culmination DBS0349793 [act15]:sadA(921-952) sadA decreased cell-substrate adhesion SA604 [act15]:sgkA:FLAG sgkA aberrant response to abiotic stimulus | increased resistance to cisplatin | aberrant cytokinesis | increased resistance to carboplatin DBS0304461 [act15]:sir2E sir2E increased growth rate HPF437 [act15]:snfA(1-379):GFP snfA increased stalk width | increased ATP level | decreased growth rate | increased number of mitochondria | decreased defense response to bacterium | decreased phototaxis | decreased stalk length | aberrant mitochondrion organization DBS0351040 [act15]:snfA(1-379):GFP/[AS]ndkC-1 ndkC-1 | ndkC-2 | snfA wild type DBS0350976 [act15]:snfA:YFP snfA decreased growth rate | aberrant fruiting body morphogenesis DBS0351053 [act15]:sod2 sod2 decreased slug migration | decreased fruiting body size | decreased superoxide generation | decreased sporulation DBS0304457 [act15]:sodA/gcsA- gcsA | sodA wild type DBS0237194 [act15]:sodA:myc sodA aberrant response to abiotic stimulus | decreased gene expression | abolished aggregation DBS0237195 [act15]:spkA:FLAG spkA-1 | spkA-2 aberrant aggregation | decreased chemotaxis rate | aberrant actin filament organization | decreased establishment of cell polarity AK1209 [act15]:tagA(1-890) tagA increased number of mound tips DBS0350962 [act15]:tor(212-2380):YFP tor decreased growth rate | aberrant sorocarp development DBS0237198 [act15]:torA torA abolished vegetative growth DBS0350862 [act15]:tpt1:YFP tpt1 decreased gene expression | decreased growth rate | decreased number of mounds | delayed development | aberrant fruiting body morphogenesis DBS0237199 [act15]:trrA trrA aberrant aggregation | decreased growth rate | decreased phagocytosis | delayed culmination DBS0351572 [act15]:vacA:GFP vacA decreased phagocytosis DBS0351573 [act15]:vacB:GFP vacB decreased phagocytosis DBS0351574 [act15]:vacC:GFP vacC decreased phagocytosis DBS0237200 [act15]:vasP vasP increased filopodium formation | increased actin filament polymerization DBS0351184 [act15]:washc5(N457D):GFP washc5 aberrant cytokinesis DBS0351183 [act15]:washc5:GFP washc5 aberrant cytokinesis DBS0350911 [act6]:GFP:cepA/cepA(183-346) cepA increased number of centrosomes DBS0237209 [act6]:GFP:cepJ cepJ decreased resistance to nocodazole | aberrant cytokinesis | decreased size of astral microtubules | decreased number of astral microtubules | increased number of microtubule organizing center DBS0351235 [act6]:GFP:cepL cepL increased number of microtubule organizing center DBS0351586 [act6]:GFP:gefQ(S431A) gefQ increased number of mound tips | delayed development DBS0349984 [act6]:GFP:lmnB(1-712) lmnB aberrant cellular response to fluid shear stress | aberrant intermediate filament organization | abolished vegetative growth DBS0351551 [act6]:GFP:lmnB(1-712)/S122A lmnB aberrant intermediate filament bundle assembly DBS0350497 [act6]:GFP:rab2A rab2A decreased pinocytosis | decreased phagocytosis | aberrant hypotonic response | increased growth rate DBS0350498 [act6]:GFP:rab2A(N118I) rab2A aberrant cell-cell adhesion | aberrant hypotonic response | increased growth rate | precocious development DBS0350499 [act6]:GFP:rab2A(Q64L) rab2A decreased autophagic cell death | aberrant cell-cell adhesion | aberrant sorocarp development | aberrant hypotonic response | increased growth rate | increased phagocytosis DBS0306243 [act6]:GFP:sun1 sun1 increased number of centrosomes | aberrant nucleus morphology | aberrant mitotic sister chromatid segregation | aberrant centromere complex assembly | aberrant centrosome organization DBS0306244 [act6]:GFP:sun1(1-722) sun1 increased number of centrosomes | aberrant nucleus morphology | aberrant mitotic sister chromatid segregation | aberrant centromere complex assembly | aberrant centrosome organization DBS0235563 [act6]:abpD(33-262) abpB decreased growth rate | delayed development DBS0237204 [act6]:canA canA wild type DBS0350685 [act6]:csaA csaA increased migratory slug size | increased calcium-independent cell-cell adhesion DBS0237205 [act6]:dia1 dia1 delayed aggregation DBS0236905 [act6]:mrps4 mrps4 precocious aggregation DBS0235444 [act6]:myc:eppA(S250A) eppA decreased growth rate | delayed development | decreased cAMP level DBS0235445 [act6]:myc:eppA(S325A) eppA decreased growth rate DBS0266836 [act6]:ptpB ptpB delayed aggregation | decreased fruiting body size DBS0237218 [act6]:ptpC ptpC increased mound size | decreased growth rate DBS0237219 [act6]:ptpC(C649S) ptpC increased mound size | decreased growth rate DBS0350807 [act6]:rabS(N137I):GFP rabS increased secretion of lysosomal enzymes | aberrant contractile vacuole organization | increased endocytic recycling DBS0350806 [act6]:rabS:GFP rabS decreased cell-cell adhesion | increased secretion of lysosomal enzymes | increased cell death | increased pinocytosis | aberrant sorocarp development | aberrant hyperosmotic response | decreased chemotaxis to cAMP | increased growth rate | increased phagocytosis DBS0350982 [act6]:rps6 rps6 aberrant cytokinesis | delayed development DBS0304410 [act6]:srsA srsA increased migratory slug size | increased mound size | decreased gene expression | delayed aggregation | aberrant fruiting body morphogenesis | decreased sporulation DBS0237220 [act6]:trap1 trap1 development arrests at loose mound stage | aberrant aggregation | abolished pinocytosis | increased gene expression | decreased gene expression | decreased growth rate DBS0350695 [act6]:yakA yakA increased gene expression | abolished vegetative growth DBS0350069 [act6]:zizB:GFP zizB aberrant cell separation during cytokinesis | increased filopodium formation DBS0304460 [act]:alrA/gcsA- alrA | gcsA wild type DBS0349955 [ampA]:RFP:ampA ampA development arrests at mound stage DBS0237221 [arkA]:arkA:myc2 arkA aberrant aggregation HM2191 [arpB]:arpB:GFP arpB decreased actin filament polymerization | decreased cell-substrate adhesion | decreased growth rate | decreased cell motility | decreased chemotaxis rate | increased bleb assembly DBS0235407 [carA]:carA(1-317) carA-1 | carA-2 delayed development DBS0351495 [cotB]:FLAG:fbxD fbxD delayed culmination HW358 [cotB]:fpaB:myc fpaB-1 | fpaB-2 increased response to hypoxia DBS0350705 [cotC]:pkaC pkaC aberrant sorocarp development | aberrant fruiting body morphogenesis | precocious development DBS0350706 [cotC]:pkaC/[spiA]:lacZ pkaC | spiA precocious gene expression DBS0350048 [cycC]:cycC:TAP cycC decreased protein level DBS0350942 [disc]:HA:rab14(N121I) rab14 decreased endosomal vesicle fusion | decreased phagocytosis DBS0350941 [disc]:HA:rab14(Q67L) rab14 increased lysosome size | increased endosomal vesicle fusion | increased phagocytosis DBS0351493 [dscA]:His:agtA agtA decreased sporulation DBS0351492 [dscA]:His:agtA(D132A) agtA aberrant stalk morphogenesis | abolished sporulation DBS0237238 [dscB]:GFP:rab8A rab8A wild type DBS0237239 [dscB]:GFP:rab8A(N128I) rab8A increased mound size | increased cell-cell adhesion | decreased fruiting body size DBS0237240 [dscB]:GFP:rab8A(Q74L) rab8A abolished aggregation | aberrant cytoskeleton organization DBS0237241 [dscB]:GFP:rab8B rab8B increased mound size DBS0237242 [dscB]:GFP:rab8B(Q74L) rab8B increased mound size DBS0305081 [dscB]:GFP:vamp7A(L35A) vamp7A increased protein localization to plasma membrane DBS0351106 [dscB]:HA:racC racC decreased exocytosis | decreased pinocytosis | decreased macropinocytosis | aberrant actin filament organization | increased phagocytosis DBS0350903 [dscB]:HA:rapB(G12V) racB decreased exocytosis | decreased phagocytosis | aberrant cytokinesis | decreased growth rate | decreased macropinocytosis | aberrant actin filament organization | aberrant cell morphology DBS0350433 [dscB]:abpB(E60K):GFP abpB abolished actin filament polymerization DBS0350820 [dscB]:cafA cafA increased gene expression | precocious development DBS0237237 [dscB]:cycB(106-436) cycB mitotic M phase arrest DBS0350922 [dscB]:dicA(1-278) dicA increased cell death | abolished protein binding | aberrant microtubule cytoskeleton organization | aberrant Golgi localization | aberrant mitotic sister chromatid segregation | aberrant centrosome organization DBS0350923 [dscB]:dicA(48-654) dicA aberrant microtubule cytoskeleton organization | aberrant Golgi localization | decreased protein binding | aberrant mitotic sister chromatid segregation | aberrant centrosome organization DBS0237243 [dscB]:myc:rac1B rac1B increased rate of endocytosis | aberrant cytokinesis | decreased growth rate | delayed development DBS0237244 [dscB]:myc:rac1B(G12V) rac1B decreased rate of endocytosis | decreased growth rate | abolished aggregation | aberrant cell morphology DBS0237245 [dscB]:myc:rac1B(Q61L) rac1B decreased rate of endocytosis | decreased growth rate | abolished aggregation | aberrant cell morphology DBS0237246 [dscB]:myc:rac1B(T17N) rac1B decreased rate of endocytosis | decreased growth rate | abolished aggregation DBS0351510 [dscB]:rac1B(G12V):myc rac1B decreased pinocytosis | decreased growth rate | aberrant cytokinesis | delayed development | aberrant actin filament organization | aberrant cell morphology DBS0351511 [dscB]:rac1B(Q61L):myc rac1B decreased growth rate | aberrant cytokinesis | delayed development | aberrant actin filament organization | aberrant cell morphology DBS0351512 [dscB]:rac1B(T17N):myc rac1B decreased pinocytosis | decreased growth rate | aberrant cytokinesis | decreased chemotaxis to folate | delayed development | aberrant actin filament polymerization | aberrant cell morphology DBS0350589 [dscB]:rapA rapA decreased pinocytosis | aberrant actin filament organization | aberrant cell morphology | increased phagocytosis DBS0350586 [dscB]:rapA(D40E) rapA aberrant actin filament organization | aberrant cell morphology DBS0350588 [dscB]:rapA(F160L) rapA aberrant actin filament organization | aberrant cell morphology DBS0350590 [dscB]:rapA(G12T) rapA decreased pinocytosis | increased phagocytosis DBS0237247 [dscB]:rapA(G12V) rapA aberrant osmosensory signaling pathway | aberrant actin filament organization | aberrant cell morphology DBS0350585 [dscB]:rapA(S19N) rapA decreased phagocytosis | aberrant cell morphology DBS0350587 [dscB]:rapA(T63Q) rapA aberrant cell morphology DBS0237248 [dscB]:rasG(G12T) rasG decreased gene expression | decreased growth rate | increased cell-cell adhesion | decreased cell motility | decreased protein kinase activation | decreased fruiting body size | abolished aggregation | aberrant cell morphology | decreased sporulation DBS0351227 [dscB]:rasG(G12T/T45Q) rasG wild type | aberrant cell morphology DBS0350933 [dscC]:kif2 kif2 aberrant cell cycle DBS0351230 [ecmAO]:rasG(G12T) rasG aberrant prestalk gene expression | aberrant culmination DBS0350703 [ecmA]:pkaC pkaC development arrests at mound stage | abolished development of tipped mound DBS0350659 [ecmA]:pkaC(9-648) pkaC development arrests at tipped mound stage DBS0350699 [ecmA]:pkaR(G135E/G261A) pkaR decreased migratory slug size | delayed development of tipped mound | aberrant culmination | aberrant slug migration | decreased prestalk gene expression | increased slug migration | aberrant prestalk cell differentiation DBS0350700 [ecmA]:pkaR(G135E/G261A)/[ecmB-frag]:lacZ pkaR abolished stalk cell differentiation DBS0350704 [ecmB]:pkaC pkaC development arrests at mound stage | abolished development of tipped mound DBS0350639 [ecmF]:expl3:myc expl3 aberrant stalk morphogenesis | delayed slug development DBS0304865 [expl7]:expl7:GFP expl7 aberrant late culminant morphology DBS0237252 [gpaA]:gpaA(G45V) gpaA delayed development DBS0237253 [gpaA]:gpaA(Q206L) gpaA increased basal disc size DBS0237254 [gpaB]:gpaB(Q208L) gpaB aberrant protein localization to plasma membrane DBS0237255 [hairpin]dct dct aberrant cytokinesis | aberrant pseudopodium formation DBS0238412 [inviable]arcB- arcB abolished vegetative growth DBS0238407 [inviable]arpB- arpB abolished vegetative growth DBS0237257 [inviable]cofA- cofA abolished vegetative growth DBS0349945 [inviable]fttB fttB abolished vegetative growth DBS0349872 [inviable]lkb1- lkb1 abolished vegetative growth DBS0237265 [inviable]phlp2- phlp2 abolished vegetative growth DBS0349948 [ndm]:ndm:RFP ndm development arrests at mound stage DBS0236086 [pdsA-agg]:pdsA pdsA precocious development DBS0236111 [pdsA-ldev]:pdsA pdsA development arrests at mound stage DBS0236484 [pkaC]:pkaC pkaC increased gene expression | precocious prespore gene expression | decreased spore cell differentiation | aberrant fruiting body morphogenesis | precocious development | precocious gene expression | decreased cAMP level DBS0350709 [pkaC]:pkaC/[dscC]:lacZ dscC-1 | dscC-2 | pkaC aberrant gene expression DBS0350196 [pkaC]:pkaC/nsfA(A1854T,T1984A,C2131A,A2398T,T2574A) nsfA | pkaC decreased spore cell differentiation DBS0350696 [pkaC]:pkaC/srfA- pkaC | srfA aberrant spore coat morphology | aberrant gene expression DBS0237289 [psmC1]:psmC1 psmC1 delayed development of tipped mound | aberrant cytokinesis | delayed gene expression DBS0349928 [pspA]:lacZ pspA aberrant prespore gene expression DBS0350658 [pspA]:pkaC(9-648) pkaC precocious sporulation | aberrant fruiting body morphogenesis DBS0350697 [pspA]:pkaR(G135E/G261A) pkaR abolished gene expression | decreased prespore gene expression | aberrant sorus color DBS0351229 [pspA]:rasG(G12T) rasG increased number of mound tips | increased prestalk gene expression | decreased prespore gene expression | abolished phototaxis | increased prestalk cell differentiation DBS0237290 [ptpA1]:ptpA1 ptpA1-1 | ptpA1-2 delayed aggregation | decreased growth rate | aberrant fruiting body morphogenesis DBS0237291 [ptpB]ptpB ptpB decreased growth rate | development arrests at mound stage DBS0351231 [rasD]:rasG(G12T) rasG development arrests at loose mound stage | increased number of mound tips DBS0236867 [rasG]:rasG(G12T) rasG aberrant aggregation SA601 [sglA-myc]neoR-1 sglA decreased resistance to carboplatin | decreased growth rate | aberrant cytokinesis | decreased resistance to cisplatin DBS0237316 [tet]:GFP(S65T):racG(G12V) racG increased filopodium formation | decreased positive regulation of GTPase activity | decreased actin filament polymerization | increased phagocytosis | abolished chemotaxis to cAMP DBS0237317 [tet]:GFP(S65T):racG(T17N) racG abolished actin filament polymerization | abolished chemotaxis to cAMP DBS0350110 [tet]:RNAi:raptor raptor decreased growth rate DBS0238351 [tet]:[RNAi]cinC cinC decreased translation | precocious aggregation | decreased growth rate DBS0237318 [tet]:pten pten decreased cell motility | decreased protein kinase activation DBS0237622 [tet]:rapA(S17N)/[act15]:gbpD gbpD | rapA increased establishment of cell polarity | increased cell-substrate adhesion | aberrant cell morphology DBS0351461 [tet]rasD(G12T) rasD increased gene expression | increased prestalk cell differentiation DBS0351463 [tet]rasD(G12T)/rigA- rasD | rigA wild type DBS0350494 [tgrB1]:[RNAi]abcB3/[tgrC1]:GFP abcB3 delayed development | decreased cAMP level DBS0351290 [tre]:drkA:myc drkA decreased growth rate | increased protein tyrosine phosphorylation DBS0304911 [tre]:paxB paxB abolished sporulation | aberrant endocytosis | decreased cell-substrate adhesion | aberrant chemotaxis to folate | development arrests at mound stage | decreased cell motility | increased cell-cell adhesion DBS0350267 [tre]:secG secG increased filopodium formation | abolished establishment of cell polarity | development arrests at mound stage | aberrant actin cytoskeleton organization | aberrant actin filament polymerization | abolished chemotaxis to cAMP | delayed gene expression DBS0351555 [unk]:FLAG:rab1A(Q67L) rab1A aberrant actin filament polymerization | aberrant pseudopodium formation DBS0351556 [unk]:FLAG:rab1A(S22N) rab1A decreased actin filament polymerization | decreased chemotaxis to cAMP DBS0351442 [unk]:GFP:RasG rasG increased macropinocytosis DBS0351443 [unk]:GFP:RasG(G12T) rasG increased macropinocytosis DBS0351444 [unk]:GFP:RasS rasS increased macropinocytosis DBS0351445 [unk]:GFP:RasS(G12V) rasS increased macropinocytosis DBS0350726 [unk]:GFP:cepE cepE increased number of centrosomes | aberrant cytokinesis DBS0351454 [unk]:GFP:piaA(G963E) piaA delayed aggregation | decreased protein binding DBS0351507 [unk]:GFP:wasA(I173A/F179A) wasA abolished protein binding DBS0350447 [unk]:PTEN(H385G/N389A/H390A) pten decreased protein localization to plasma membrane | decreased fruiting body size DBS0351270 [unk]:gpgA(1-65) gpgA decreased protein localization to plasma membrane | abolished aggregation | aberrant actin filament organization | abolished chemotaxis to cAMP DBS0350576 [unk]:mhkC(1-498) mhkC abolished protein localization to cell cortex | abolished protein phosphorylation DBS0350405 [unk]:myc:rgaA(K273E/K282E) rgaA aberrant binding DBS0350716 [unk]:pdsA pdsA aberrant sorocarp development DBS0350259 [unk]:pikA(1-492(S7A/S11A/S109A/S113A/S177A/S181A)) pikA increased protein localization to plasma membrane DBS0350558 [unk]:pikI(T262E) pikI increased catalytic activity DBS0350258 [unk]:rapA(G12V) rapA increased activation of GTPase activity DBS0236859 [unk]:rasD(G12T) rasD increased myo-inositol level | decreased gene expression | increased prestalk gene expression | decreased prespore gene expression | development arrests at tipped mound stage | increased protein kinase activation DBS0350837 [unk]:rasD(G12T)/[rasD]:rapA rapA | rasD increased number of mound tips | aberrant culmination | decreased prespore cell differentiation | aberrant gene expression | decreased stalk cell differentiation DBS0304636 [unk]:rasG(Q61L)/rasG- rasG aberrant extracellular cAMP signaling pathway | increased protein modification DBS0350597 [unk]:roco4(1018-1292;F1107L,F1161L) roco4 decreased small molecule binding DBS0238439 [unk]:scrA(97-443):GFP scrA aberrant cytokinesis | increased vegetative cell size | decreased chemotaxis to cAMP | aberrant cytoskeleton organization DBS0351430 [unk]:tps9(N236A) tps9 decreased catalytic activity DBS0350056 [unk]:tubA:GFP/RNAi]cepG cepG | tubA aberrant cytokinesis | aberrant microtubule cytoskeleton organization | aberrant protein localization to nuclear envelope | aberrant centromere complex assembly DBS0350913 [unk]:tubA:GFP/[RNAi]cepD cepD increased number of centrosomes | aberrant mitotic spindle organization | decreased protein localization to microtubule organizing center DBS0351237 [unk]:tubA:GFP/[RNAi]cepL cepL | tubA decreased growth rate | aberrant cytokinesis | aberrant microtubule cytoskeleton organization | aberrant centromere complex assembly DBS0351561 [unk]:vacA:myc:vasP vacA | vasP decreased phagocytosis | decreased growth rate | aberrant cytokinesis | increased protein level | aberrant cell morphology DBS0350464 [unk]:vasP(1-197:221-261:285-380) vasP abolished actin filament polymerization DBS0350463 [unk]:vasP(1-261:285-380) vasP aberrant actin filament organization DBS0350465 [unk]:vasP(1-340:376-380) vasP decreased actin filament polymerization | aberrant actin filament organization DBS0237288 [unk]skp1 fpaA | fpaB-1 aberrant fruiting body morphogenesis HAD186 aarA- aarA aberrant stalk morphogenesis | aberrant Golgi localization | aberrant epithelium-like organization | decreased prespore gene expression | aberrant centrosome localization | aberrant stalk development | aberrant establishment or maintenance of cell polarity | decreased sporulation DBS0349920 aarA-/[act15]:GFP-mhcA aarA aberrant stalk morphogenesis | aberrant protein localization DBS0350143 abcA10- abcA10 aberrant sorocarp development | decreased sporulation DBS0350135 abcA3- abcA3 aberrant sorocarp development | aberrant fruiting body morphogenesis | decreased sporulation DBS0350138 abcA4- abcA4 aberrant fruiting body morphogenesis DBS0350139 abcA5- abcA5 aberrant sorocarp development | decreased sporulation DBS0350140 abcA6- abcA6 decreased fruiting body size DBS0350141 abcA7- abcA7 aberrant sorocarp development DBS0350142 abcA9- abcA9 aberrant fruiting body morphogenesis | decreased sporulation DBS0350145 abcB1- abcB1 delayed culmination DBS0350146 abcB4- abcB4 decreased sporulation DBS0350147 abcB5- abcB5 decreased growth rate | delayed culmination DBS0350153 abcC13- abcC13 aberrant sorocarp development | delayed culmination | decreased sporulation DBS0350154 abcC14- abcC14 aberrant sorocarp development | decreased fruiting body size | decreased sporulation DBS0350148 abcC2- abcC2 aberrant sorocarp development | delayed culmination DBS0350149 abcC3- abcC3 delayed culmination DBS0350150 abcC6- abcC6 aberrant sorocarp development | delayed culmination DBS0350151 abcC8- abcC8 decreased growth rate | increased number of early culminant tips | decreased sporulation DBS0350155 abcD2- abcD2 decreased fruiting body size DBS0350156 abcF1- abcF1 aberrant sorocarp development | delayed culmination | decreased sporulation DBS0350157 abcF2- abcF2 delayed development of tipped mound | decreased sporulation DBS0350158 abcF4- abcF4 aberrant sorocarp development | aberrant fruiting body morphogenesis DBS0350164 abcG10- abcG10 delayed development of tipped mound | decreased fruiting body size | decreased sporulation DBS0350165 abcG15- abcG15 aberrant sorocarp development | decreased sporulation DBS0350166 abcG16- abcG16 delayed culmination DBS0350167 abcG17- abcG17-1 | abcG17-2 decreased fruiting body size | decreased sporulation DBS0350168 abcG18- abcG18 decreased sporulation DBS0350169 abcG19- abcG19 delayed aggregation | decreased fruiting body size DBS0350160 abcG2- abcG2 delayed development of tipped mound | decreased fruiting body size DBS0236539 abcG2-/abcG18- abcG18 | abcG2 decreased rate of endocytosis | decreased growth rate | abolished vegetative growth DBS0236540 abcG2-/abcG18-/rtoA- abcG18 | abcG2 | rtoA decreased growth rate | abolished vegetative growth DBS0350170 abcG22- abcG22 delayed development of tipped mound | aberrant sorocarp development DBS0350171 abcG24- abcG24 decreased sporulation | delayed culmination DBS0350161 abcG5- abcG5 delayed culmination DBS0350162 abcG6- abcG6 decreased sporulation DBS0351078 abcG6- abcG6 delayed aggregation | increased cell-substrate adhesion | decreased cell motility DBS0350163 abcG7- abcG7 delayed development of tipped mound | decreased fruiting body size | decreased sporulation DBS0350159 abcH2- abcH2 decreased sporulation DBS0266687 abiA- abiA abolished protein localization to pseudopodium | decreased protein level | aberrant cytokinesis | decreased growth rate | decreased chemotaxis to folate DBS0266688 abiA- abiA abolished protein localization to pseudopodium DBS0351531 abiA-/AX2 abiA abolished protein localization to pseudopodium | decreased migratory slug size | aberrant filopodium formation | aberrant macropinocytosis | decreased cell motility | aberrant pseudopodium formation | decreased fruiting body size DBS0350386 abiA-/abiA(45-136) abiA decreased protein level | aberrant cytokinesis DBS0350384 abiA-/abiA(45-332) abiA aberrant cytokinesis DBS0351535 abiA-/pirA-/AX2 abiA | pirA aberrant macropinocytosis | decreased cell motility | aberrant cell morphology DBS0266689 abiA-/scrA- abiA | scrA decreased cell motility | decreased vegetative cell size LAS53 abkD- abkD aberrant socially cooperative development DBS0351065 abnC- abnC delayed aggregation | increased cell-substrate adhesion | decreased cell motility DBS0235459 abpA- abpA aberrant hyperosmotic response DBS0235456 abpA-/abpC- abpA | abpC decreased pinocytosis | decreased phagocytosis | decreased growth rate | decreased cell motility | aberrant sorocarp development | aberrant cell-cell adhesion | aberrant hyperosmotic response DBS0305672 abpB- abpB increased filopodium formation DBS0351087 abpB-/abpA- abpA | abpB decreased pinocytosis | decreased growth rate | increased cell-cell adhesion | decreased vegetative cell size | aberrant fruiting body morphogenesis | aberrant hyperosmotic response | precocious gene expression | decreased chemotaxis to cAMP DBS0351088 abpB-/abpC- abpB | abpC decreased prespore gene expression | decreased prestalk gene expression | aberrant fruiting body morphogenesis | aberrant hyperosmotic response | decreased chemotaxis to cAMP DBS0235425 abpB-/fimA- abpB | fimA decreased vegetative cell size | decreased fruiting body size | decreased sporulation HG1264 abpC- abpC aberrant actin cytoskeleton organization DBS0350936 abpC- abpC aberrant cortical actin cytoskeleton organization | decreased phagocytosis | decreased cell motility | decreased chemotaxis to cAMP | aberrant pseudopodium formation | decreased establishment of cell polarity DBS0236077 abpC- abpC decreased response to Gram-negative bacterium | aberrant thermotaxis | aberrant cortical actin cytoskeleton organization | decreased cell motility | aberrant phototaxis | decreased establishment of cell polarity | aberrant actin filament polymerization HG1270 abpC- abpC aberrant phototaxis DBS0237938 abpC-/[act15]:GFP:abpC(9-148) abpC aberrant phototaxis DBS0235426 abpC-/[act15]:abpC abpC wild type DBS0350938 abpC-/[act15]:abpC abpC wild type DBS0237945 abpC-/[act15]:abpC(1-348:449-857):GFP abpC aberrant phototaxis | aberrant actin filament organization DBS0237946 abpC-/[act15]:abpC(1-556:644-857):GFP abpC aberrant phototaxis | aberrant actin filament organization DBS0237941 abpC-/[act15]:abpC(1-739):GFP abpC aberrant phototaxis DBS0351553 abpC-/[act15]:qkgA(425-1553) abpC | qkgA-1 | qkgA-2 aberrant actin filament polymerization DBS0237949 abpC-/[cotB]:abpC:GFP abpC aberrant phototaxis DBS0237948 abpC-/[ecmA]:abpC:GFP abpC wild type DBS0235427 abpD- abpD decreased cell-cell adhesion | decreased spore germination | aberrant sorocarp development | delayed development DBS0235428 abpE- abpE-1 | abpE-2 increased lateral pseudopodium formation DBS0349851 abpE- abpE-1 | abpE-2 aberrant phagosome maturation | precocious phagosome acidification | increased phagocytosis DBS0349852 abpE-/[act15]:abpE abpE-1 | abpE-2 decreased phagocytosis DBS0350529 abpG- abpG increased actin filament polymerization | decreased chemotaxis to cAMP | decreased fruiting body size DBS0235562 acaA- acaA abolished stream development | abolished gene expression | abolished establishment of cell polarity | decreased gene expression | increased cellular thermotolerance | abolished aggregation | decreased adenylate cyclase activity | decreased cAMP level GP6 acaA- acaA increased lateral pseudopodium formation | decreased chemotaxis rate | aberrant actin filament organization | aberrant cell morphology | increased protein kinase activation DBS0235429 acaA- acaA decreased gene expression | abolished oscillatory cAMP signaling DBS0350720 acaA-/[acaA-agg]:acaA:myc acaA decreased gene expression | decreased fruiting body size DBS0350721 acaA-/[acaA-psp]:acaA:myc acaA decreased gene expression | decreased mound size | decreased fruiting body size DBS0350722 acaA-/[acaA-pst]:acaA:myc acaA wild type DBS0350702 acaA-/[act15]:HA:pkaC acaA | pkaC wild type | delayed development | decreased cAMP level DBS0350725 acaA-/[act15]:HA:pkaC/acrA- acaA | acrA | pkaC decreased gene expression | abolished adenylate cyclase activity | development arrests at tipped mound stage DBS0350737 acaA-/[act15]:acaA acaA aberrant slug development DBS0350738 acaA-/[act15]:acaA(1-390;398-1407) acaA abolished aggregation DBS0350739 acaA-/[act15]:acaA(L394T/K482N) acaA wild type DBS0350603 acaA-/[act15]:cap:GFP acaA | cap development arrests at loose mound stage | increased calcium-dependent cell-cell adhesion | wild type DBS0350735 acaA-/[act15]:pkaR(G135E/G261A) acaA | pkaR increased cAMP level DBS0350736 acaA-/[unk]:acaA(F306L/S498G,K504E,E593V,I649T) acaA decreased gene expression | abolished oscillatory cAMP signaling | decreased cAMP level DBS0350734 acaA-/[unk]:acaA(N333D,G633S) acaA abolished adenylate cyclase activity DBS0350733 acaA-/[unk]:acaA(V427I,S642F) acaA abolished activation of adenylate cyclase activity DBS0350711 acaA-/[unk]:acgA acaA | acgA aberrant sorocarp development DBS0306125 acapA- acapA wild type DBS0350051 acapA- acapA aberrant exocytosis | aberrant filopodium formation | increased defense response to Gram-negative bacterium | aberrant endocytosis | aberrant cytokinesis | aberrant stream morphology | decreased cell motility | delayed development | aberrant lysosome organization DBS0350055 acapA-/[act15]:acapA(R633Q):GFP acapA aberrant filopodium formation | aberrant lysosome organization DBS0350054 acapA-/[act15]:acapA:GFP acapA increased filopodium formation DBS0306126 acapA-/acapB- acapA | acapB decreased sporulation DBS0306127 acapB- acapB wild type TL177 acbA- acbA decreased response to Gram-negative bacterium | abolished cell migration to prestalk region | abolished spore cell differentiation | decreased sporulation | decreased resistance to cisplatin DBS0350194 acbA-/[act15]:acbA(Y72A) acbA abolished spore cell differentiation AK1211 acbA-/tagA- acbA | tagA increased prestalk B cell differentiation DBS0235440 acgA- acgA abolished polyketide metabolic process | decreased spore germination | decreased spore cell differentiation | precocious spore germination | abolished response to biotic stimulus DBS0237788 acgA- acgA decreased prespore cell differentiation | decreased prespore gene expression DBS0237790 acgA-/[acrA]:lacZ acgA | acrA aberrant prestalk gene expression DG1100 acrA- acrA decreased gene expression | increased stalk length | decreased prespore gene expression | decreased sporulation DBS0349939 acrA- acrA aberrant spore coat morphology | decreased stalk width DBS0350723 acrA-/[act15]:acaA(L394S) acaA | acrA precocious spore germination DBS0237786 acrA-/[act15]:acgA(1-401) acgA | acrA decreased prespore gene expression | decreased prespore cell differentiation | decreased sporulation DBS0349970 acrA-/[act15]:acrA(D1010A) acrA decreased adenylate cyclase activity DBS0349971 acrA-/[act15]:acrA(D1174A) acrA increased adenylate cyclase activity DBS0349969 acrA-/[act15]:acrA(N796D/D854A/G856A) acrA wild type DBS0350724 acrA-/[pkaC]:pkaC acrA | pkaC decreased spore germination | decreased fruiting body size | precocious development | decreased sporulation DBS0351249 act5-/[act5]:RFP/NC4 act5 increased chemotaxis to folate | increased fruiting body size | increased growth rate DBS0350443 adcB- adcB wild type DBS0350444 adcC- adcC wild type DBS0351190 adcC-/[act15]:adcC(1-485) adcC decreased protein localization to plasma membrane DBS0351189 adcC-/[act15]:adcC(101-654):GFP adcC abolished protein localization to plasma membrane DBS0350445 adcC-/adcB- adcB | adcC increased oscillatory cAMP signaling | aberrant endocytosis | delayed aggregation | aberrant regulation of protein kinase activity DBS0350538 adprt1A- adprt1A decreased resistance to phleomycin | decreased double-strand break repair via nonhomologous end joining DBS0351248 adprt1A- adprt1A decreased gene expression | increased gene expression | decreased ATP level | delayed mitotic cell cycle | decreased growth rate | delayed aggregation | increased prestalk gene expression | decreased mound size | aberrant response to oxidative stress | decreased fruiting body size | increased mitochondrial fission | decreased cAMP level | abolished chemotaxis to cAMP DBS0350541 adprt1A-/adprt2- adprt1A | adprt2 decreased resistance to phleomycin | decreased double-strand break repair via nonhomologous end joining | decreased resistance to cisplatin DBS0264268 adprt1B- adprt1B wild type | decreased single-strand break repair | aberrant oscillatory cAMP signaling DBS0350539 adprt2- adprt2 decreased single-strand break repair | decreased double-strand break repair | decreased resistance to cisplatin DBS0238203 adrm1- adrm1-1 decreased catalytic activity | precocious gene expression | aberrant response to nutrient | precocious development DBS0351596 agnA- agnA increased pre-miRNA processing | aberrant production of siRNA involved in RNA interference | increased gene expression | abolished transitive RNA interference DBS0351603 agnA-/agnB- agnA | agnB aberrant production of siRNA involved in RNA interference | increased gene expression DBS0351602 agnB- agnB decreased gene expression HW420 agtA- agtA development arrests at slug stage HW520 agtA-/gnt1(1-253/H104D) agtA | gnt1 development arrests at slug stage DBS0235457 ahhA- ahhA aberrant late culminant morphology DBS0252637 aip1- aip1 decreased pinocytosis | delayed cytokinesis | decreased growth rate | decreased phagocytosis | increased actin filament polymerization | aberrant nucleus morphology | decreased cell motility DBS0266759 alp- alp wild type DBS0235513 alrA- alrA increased mound size | decreased cell motility | decreased glucose level | decreased protein secretion DBS0235473 alrA-/[act15]:alrA alrA wild type DBS0235474 alxA- alxA development arrests at loose mound stage | aberrant standing slug morphology | decreased growth rate DBS0235475 alxA- alxA abolished sporulation | aberrant standing slug morphology | aberrant cellular process | decreased gene expression | development arrests at mound stage DBS0235488 alxA-/[act15]:FLAG:alxA alxA delayed development DBS0235476 alxA-/[act15]:alxA(1-596):myc2 alxA aberrant standing slug morphology DBS0235477 alxA-/[act15]:alxA(1-697):myc2 alxA wild type DBS0235478 alxA-/[act15]:alxA(155-697):myc2 alxA aberrant standing slug morphology DBS0235479 alxA-/[act15]:alxA(293-697):myc2 alxA aberrant standing slug morphology DBS0235480 alxA-/[act15]:alxA(460-794):myc2 alxA aberrant standing slug morphology DBS0235481 alxA-/[act15]:alxA(D310A/N311A) alxA wild type DBS0235482 alxA-/[act15]:alxA(Q181E/Q183) alxA wild type DBS0235483 alxA-/[act15]:alxA(S700A/S704A/S708A) alxA wild type DBS0235484 alxA-/[act15]:alxA(S700D/S704D/S708D) alxA wild type DBS0235485 alxA-/[act15]:alxA(Y315D) alxA wild type DBS0235486 alxA-/[act15]:alxA(Y315F) alxA wild type DBS0235487 alxA-/[act15]:alxA:myc2 alxA wild type DBS0235489 alyA- alyA increased phagocytosis AK1350 alyL- alyL decreased response to Gram-negative bacterium DG1114 amdA- amdA decreased spore germination | aberrant sorus color | increased prestalk A cell differentiation HM1158 amdA- amdA decreased fruiting body size | decreased sporulation | increased cell differentiation DBS0235490 amiB- amiB abolished aggregation DBS0235491 amiB- amiB aberrant cell motility | increased gene expression | decreased gene expression | decreased oscillatory cAMP signaling | decreased cGMP-mediated signaling | abolished aggregation | decreased chemotaxis to cAMP DBS0235493 ampA- ampA delayed development of tipped mound | delayed prestalk gene expression | precocious prespore gene expression | increased cell-cell adhesion | increased cell-substrate adhesion | aberrant gene expression | delayed development | decreased prestalk cell differentiation DBS0349962 ampA- ampA wild type | decreased actin filament polymerization | aberrant chemotaxis to folate | increased cell-substrate adhesion | decreased pseudopodium formation DBS0349951 ampA-/lmbd2B- ampA | lmbd2B aberrant chemotaxis DBS0235496 ampA-/pspD:lacZ ampA aberrant prespore gene expression DBS0349963 ampA-/sma- ampA | sma increased chemotaxis to folate | increased cell-substrate adhesion DBS0349953 ampA/[ampA]:TAP ampA increased protein secretion | development arrests at mound stage DBS0235495 ampA/[ampA]:ampA ampA decreased cell-substrate adhesion | increased pinocytosis | increased actin filament polymerization | aberrant chemotaxis to folate | increased pseudopodium formation DBS0349952 ampA/[ampA]:ampA/lmbd2B- ampA | lmbd2B aberrant chemotaxis BS155 amtA- amtA decreased slug migration | decreased mound size | decreased fruiting body size | increased growth rate | decreased ammonia level DBS0267100 amtA- amtA increased number of mounds | increased glucose level | decreased mound size | decreased ammonia level | decreased stalk length | aberrant sporulation | increased intracellular ammonia level DBS0267101 amtA-/[OE]:amtA amtA wild type BS165 amtA-/amtC- amtA | amtC decreased protein localization to nucleus | aberrant slug migration | decreased ammonia level | delayed gene expression amtB- amtB BS169 amtB-/amtA- amtA | amtB decreased ammonia level BS168 amtB-/amtC- amtB | amtC decreased ammonia level BS154 amtC- amtC abolished protein localization to nucleus | development arrests at slug stage | aberrant gene expression | decreased prestalk gene expression | aberrant fruiting body morphogenesis | decreased ammonia level | delayed culmination DBS0235501 amtC-/[act15]:cudA amtC | cudA delayed culmination DBS0235502 amtC-/[ecmA]:cudA amtC | cudA delayed culmination DBS0235503 amtC-/[pspA]:cudA amtC | cudA development arrests at slug stage BS163 amtC-/dhkC- amtC | dhkC aberrant gene expression DBS0236890 amtC-/regA- amtC | regA precocious sporulation DBS0350432 aoxA- aoxA decreased resistance to hydrogen peroxide | aberrant cellular process | aberrant sorocarp development DBS0349869 ap1b1- ap1b1 aberrant aggregation | aberrant cell separation during cytokinesis | aberrant contractile vacuole organization | decreased growth rate | aberrant hypotonic response | decreased protein stabilization DBS0305197 ap2a1- ap2a1-1 | ap2a1-2 aberrant cell separation during cytokinesis DBS0350296 aph1- aph1 aberrant culmination | abolished catalytic activity | decreased prespore cell differentiation DBS0351357 aph1- aph1 increased protein modification | decreased phagocytosis | decreased macropinocytosis | aberrant sorocarp development | decreased protein processing in phagocytic vesicle | delayed phagosome acidification DBS0350299 aph1-/ncstn- aph1 | ncstn decreased phagocytosis | decreased prespore cell differentiation DBS0350300 aph1-/psenA- aph1 | psenA aberrant culmination | abolished catalytic activity | decreased prespore cell differentiation DBS0350805 apl- apl aberrant response to cisplatin DBS0351160 aplD- aplD decreased defense response to Gram-negative bacterium | decreased growth rate DBS0351161 aplP- aplD decreased growth rate DBS0235505 apm1- apm1 decreased spore germination | aberrant contractile vacuole organization | decreased growth rate | aberrant endosome morphology | aberrant hypotonic response | delayed development | decreased stalk width DBS0235506 apm2- apm2 aberrant cell separation during cytokinesis DBS0305085 apm2-/[dscB]:GFP:vamp7A apm2 | vamp7A increased protein localization to plasma membrane DBS0235507 apm3- apm3 decreased pinocytosis | increased exocytosis | aberrant endosome morphology | decreased cellular localization | aberrant secretion | aberrant lysosome organization DBS0305083 apm3-/[dscB]:GFP:vamp7A apm3 | vamp7A increased protein localization to plasma membrane DBS0235508 apm4- apm4 wild type DBS0235509 aprA- aprA aberrant cellular homeostasis | increased mound size | decreased spore germination | increased cell death | aberrant cytokinesis | aberrant vegetative growth | aberrant fruiting body morphogenesis | increased growth rate | abolished chemorepellant activity | decreased sporulation DBS0235510 aprA-/[act15]:aprA aprA decreased growth rate | aberrant fruiting body morphogenesis DBS0350009 aprA-/[act15]:bzpN:GFP aprA | bzpN abolished negative regulation of vegetative growth DBS0238124 aqpA- aqpA decreased spore germination | decreased sporulation DBS0351484 aqpB- aqpB decreased cell motility DBS0351067 araA- araA delayed aggregation | increased cell-substrate adhesion | decreased cell motility | increased protein kinase activation HM2245 arcB(I191L/D197Y/K206V/A213V/F223L/P224S/E232G/I237T/H245L/S250S) arcB decreased actin filament polymerization | decreased growth rate | decreased cell motility | decreased chemotaxis rate | decreased pseudopodium formation DBS0350886 areA- areA increased autophagy DBS0350887 areB- areB increased autophagy DBS0235511 arkA- arkA increased gene expression | aberrant fruiting body morphogenesis DBS0235512 arkA-/[arkA]:arkA:myc2 arkA aberrant aggregation DBS0350000 arpB+/aprB-/[act15]:myc:arpB(T235A/T236A) arpB wild type DBS0349998 arpB+/aprB-/[act15]:myc:arpB(Y200F/T235A/T236A) arpB decreased actin filament polymerization | delayed aggregation | decreased fruiting body size | decreased establishment of cell polarity | decreased chemotaxis to cAMP | delayed gene expression DJK45 arpB+/arpB- arpB wild type DMZ10 arpB+/arpB-/[act15]:myc:arpB arpB wild type MZ10 arpB-/[act15]:myc:arpB arpB wild type DBS0350191 arpin- arpin increased cell motility DBS0350206 arpin-/[act15]:GFP:arpin arpin wild type DBS0350654 ase1A- ase1A aberrant mitotic spindle organization | aberrant cytokinesis | aberrant microtubule cytoskeleton organization DBS0350655 ase1B- ase1B aberrant cell morphology DBS0235514 aslA- aslA-1 | aslA-2 wild type DBS0351219 ate1- ate1 aberrant cell motility | decreased cell-substrate adhesion | decreased vegetative cell size | aberrant actin filament organization DBS0236305 atg1- atg1 aberrant macroautophagy | abolished autophagosome organization DBS0236304 atg1- atg1 aberrant macroautophagy | aberrant mitochondrion morphology | abolished autophagosome organization DBS0350450 atg1- atg1 aberrant autophagy | decreased defense response to Gram-negative bacterium | aberrant defense response to bacterium | aberrant vacuole organization DBS0350839 atg1- atg1 decreased catalytic activity | abolished protein localization to autophagosome HR131 atg1- atg1 abolished macroautophagy | increased number of autophagosomes | aberrant autophagy | decreased defense response to Gram-negative bacterium | aberrant cellular response to nitrogen starvation | decreased growth rate | abolished spore cell differentiation | aberrant vacuole organization | abolished stalk cell differentiation | abolished aggregation | increased defense response to fungus | decreased defense response to Gram-positive bacterium | aberrant protein localization DBS0238085 atg1-/[act15]:atg1 atg1 wild type DBS0238092 atg1-/[act15]:atg1(1-628) atg1 aberrant cellular response to nitrogen starvation | abolished aggregation DBS0238087 atg1-/[act15]:atg1(K36A) atg1 aberrant cellular response to nitrogen starvation | abolished aggregation DBS0238089 atg1-/[act15]:atg1(K36A/1-628) atg1 aberrant cellular response to nitrogen starvation | abolished aggregation DBS0238093 atg1-/[act15]:atg1(P138S) atg1 abolished aggregation DBS0266655 atg1-/iplA- atg1 | iplA decreased necrotic cell death DBS0252632 atg1-/pcp- atg1 | pcp abolished autophagosome organization DBS0351613 atg1-/tsg101- atg1 | tsg101 decreased defense response to Gram-positive bacterium DBS0350838 atg1-/vmp1- atg1 | vmp1 wild type | abolished protein localization to autophagosome DBS0350884 atg101- atg101 increased number of tip-organizers | decreased autophagy DBS0351232 atg12- atg12 decreased pinocytosis | increased cell death | decreased spore germination | decreased catalytic activity | increased gene expression | increased number of mound tips | increased protein modification | decreased phagocytosis | aberrant phagosome maturation | aberrant fruiting body morphogenesis DBS0351233 atg12-/tipD- atg12 | tipD decreased pinocytosis | increased cell death | decreased spore germination | increased gene expression | increased number of mound tips | increased protein modification | decreased phagocytosis | aberrant phagosome maturation | aberrant fruiting body morphogenesis DBS0350883 atg13- atg13 aberrant autophagy | abolished aggregation DBS0350885 atg17- atg17 wild type HR75 atg5- atg5 increased number of tip-organizers | aberrant macroautophagy | abolished sporulation | aberrant cellular response to nitrogen starvation | abolished aggregation | aberrant protein localization DBS0351478 atg5- atg5 abolished sporulation | decreased gene expression | delayed development DBS0351582 atg5- atg5 increased cell death | decreased catalytic activity | decreased growth rate | aberrant phagocytosis | increased protein modification | decreased macropinocytosis | aberrant fruiting body morphogenesis | increased growth rate DBS0351576 atg5-/abpB-/[dscB]:abpB(D93A/D95A/D97A):GFP abpB | atg5 aberrant cellular component organization | abolished vegetative growth DBS0351583 atg5-/atg12- atg12 | atg5 increased cell death | decreased catalytic activity | decreased growth rate | decreased phagocytosis | increased protein modification | decreased macropinocytosis | aberrant fruiting body morphogenesis DBS0351584 atg5-/atg12-/tipD- atg12 | atg5 | tipD increased cell death | decreased catalytic activity | decreased growth rate | aberrant phagocytosis | increased protein modification | decreased macropinocytosis | aberrant fruiting body morphogenesis | increased growth rate HR174 atg6- atg6A increased number of tip-organizers | aberrant macroautophagy | decreased defense response to Gram-negative bacterium | aberrant cellular response to nitrogen starvation | decreased spore cell differentiation | decreased defense response to fungus | decreased fruiting body size | decreased stalk length | decreased sporulation HR79 atg7- atg7 increased number of tip-organizers | aberrant macroautophagy | abolished sporulation | decreased defense response to Gram-negative bacterium | aberrant cellular response to nitrogen starvation | abolished spore cell differentiation | aberrant protein localization DBS0351476 atg7- atg7 aberrant sorus morphology | decreased spore germination | decreased gene expression | decreased prespore cell differentiation | delayed development DBS0351477 atg7-/[act15]:YFP:atg7(C563A) atg7 aberrant sorus morphology | decreased spore germination | delayed development DBS0351479 atg7-/[act15]:pkaC:YFP atg7 | pkaC decreased gene expression | decreased sporulation HR141 atg8- atg8a increased number of tip-organizers | aberrant macroautophagy | aberrant spore morphology | aberrant cellular response to nitrogen starvation | decreased spore cell differentiation | aberrant vacuole organization | decreased fruiting body size | decreased defense response to Gram-positive bacterium | decreased sporulation DBS0351222 atg8a- atg8a increased cell death | decreased catalytic activity | increased number of mound tips | decreased growth rate | decreased phagocytosis | increased protein modification | delayed development | decreased fruiting body size | aberrant lysosome organization DBS0351224 atg8a-/atg8b- atg8a | atg8b increased cell death | decreased catalytic activity | decreased growth rate | decreased phagocytosis | increased protein modification | aberrant sorocarp development | aberrant lysosome organization DBS0351223 atg8b- atg8b precocious development | aberrant lysosome organization DBS0305977 atg9- atg9 increased stalk width | decreased pinocytosis | abolished sporulation | aberrant sorus morphology | aberrant autophagy | decreased protein localization to autophagosome | increased number of mound tips | decreased gene expression | decreased phagocytosis | decreased growth rate | abolished catalytic activity | aberrant slug development | aberrant slug migration | aberrant protein modification | aberrant phagosome maturation | decreased prespore cell differentiation | aberrant fruiting body morphogenesis | delayed development | abolished phototaxis DBS0305978 atg9-/[act15]:GFP:atg9 atg9 wild type DBS0305979 atg9-/[act15]:atg9:GFP atg9 wild type DBS0350535 atg9-/[act15]:cdcD(R154C):RFP atg9 | cdcD decreased growth rate | decreased phototaxis DBS0351589 atg9-/[act15]:cdcD(R154C/E219K):RFP atg9 | cdcD wild type DBS0350534 atg9-/[act15]:cdcD:RFP atg9 | cdcD decreased growth rate | aberrant fruiting body morphogenesis | abolished phototaxis DBS0351480 atg9-/[act15]:pkaC:YFP atg9 | pkaC abolished sporulation DBS0350731 atg9-/tipD- atg9 | tipD decreased pinocytosis | aberrant phagosome maturation | development arrests at tipped mound stage DBS0351043 atp1- atp1 decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis DBS0351044 atp6- atp6 decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis HM1591 axeB- axeB aberrant macropinocytosis | increased macropinocytosis | increased phagocytosis DBS0351503 bcas3- bcas3 decreased number of autophagosomes | aberrant fruiting body morphogenesis | aberrant phototaxis | decreased sporulation DBS0351039 bzpF- bzpF decreased spore germination | decreased gene expression | aberrant fruiting body morphogenesis | aberrant sporulation | decreased sporulation DBS0349965 bzpN- bzpN aberrant cytokinesis | abolished negative regulation of vegetative growth | increased growth rate DBS0349966 bzpN-/[act15]:bzpN:GFP bzpN wild type DBS0350419 bzpR- bzpR increased stalk width | aberrant sorus morphology | decreased sporulation DBS0351486 c2gapB- c2gapB increased cell motility | increased activation of GTPase activity DBS0351619 cadA- cadA aberrant vegetative growth TL97 cadA- cadA increased number of tip-organizers | decreased calcium-dependent cell-cell adhesion | decreased protein level | increased gene expression | abolished cell migration to prestalk region | increased chemotaxis to cAMP | aberrant cytokinesis | decreased sporulation | delayed culmination | increased prestalk cell differentiation DBS0351372 cadA- cadA aberrant defense response to bacterium | decreased growth rate | aberrant response to oxidative stress DBS0235561 cap- cap decreased protein level | aberrant pinocytosis | aberrant contractile vacuole organization | aberrant cytokinesis | decreased cell motility | delayed development | aberrant response to osmotic stress JB4 carA- carA-1 | carA-2 abolished aggregation JS14 carA- carA-1 | carA-2 abolished protein tyrosine phosphorylation | abolished protein localization to nucleus | aberrant phagocytosis | increased cell-substrate adhesion | decreased oscillatory cAMP signaling | decreased cGMP-mediated signaling | aberrant regulation of GTPase activity | abolished aggregation | aberrant regulation of protein kinase activity | abolished chemotaxis to cAMP DBS0351266 carA-/[act15]:gpbA:YFP carA-1 | carA-2 | gpbA abolished aggregation DBS0350431 carA-/[unk]:carA(261-359;S299A,S302G,S303G,S304G,S308A,S324G,S325A,S331A)(369-392;S383A,S385A):eYFP carA-1 | carA-2 aberrant adaptation of signaling pathway | aberrant protein localization to plasma membrane RI9 carA-/carC- carA-1 | carA-2 | carC decreased gene expression | abolished protein localization to plasma membrane RI4 carA-/carC- carA-1 | carA-2 | carC decreased actin filament polymerization | abolished activation of GTPase activity | abolished aggregation | abolished cGMP-mediated signaling | abolished chemotaxis to cAMP DBS0350568 carA-/carC-/[act15]:carA(261-359;S299A,S302G,S303G,S304G,S308A,S324G,S325A,S331A)(369-392;S383A,S385A) carA-1 | carA-2 | carC abolished stream development | aberrant activation of adenylate cyclase activity | aberrant chemotaxis to cAMP | aberrant oscillatory cAMP signaling | aberrant actin filament polymerization DBS0235570 carB- carB development arrests at mound stage DBS0350661 carB- carB development arrests at mound stage | abolished development of tipped mound | increased prespore gene expression | decreased prestalk gene expression JB6 carC- carC wild type DBS0235568 carD- carD decreased migratory slug size | decreased slug migration | increased prespore gene expression | decreased prestalk gene expression | aberrant slug migration | aberrant fruiting body morphogenesis | decreased stalk length | decreased prestalk cell differentiation DBS0235573 carmil- carmil decreased pinocytosis | decreased actin filament polymerization | decreased growth rate | decreased mound size DBS0266775 catA- catA abolished catalase activity X9 catA- catA decreased resistance to hydrogen peroxide | abolished catalase activity IR40 catA- catA abolished catalase activity IR41 catA- catA abolished catalase activity IR29 catA- catA decreased resistance to hydrogen peroxide DBS0235574 catB- catB decreased spore resistance to hydrogen peroxide | aberrant gene expression | delayed development | delayed gene expression DBS0350249 cbhA- cbhA delayed development DBS0350250 cbhA-/[cbhA]:cbhA cbhA wild type DBS0304455 cblA- cblA-1 | cblA-2 aberrant slug development | abolished basal disc formation | aberrant signal transduction DBS0351096 cbpG- cbpG decreased cell-substrate adhesion | decreased vegetative cell size DBS0235575 cbpJ- cbpJ wild type DBS0350238 ccdc53- ccdc53 abolished exocytosis | decreased growth rate | abolished phagosome reneutralization | abolished actin filament polymerization DBS0235661 cdk8- cdk8 decreased gene expression | aberrant gene expression | abolished aggregation DBS0350435 cdk8- cdk8 decreased spore germination | decreased gene expression | aberrant gene expression | abolished aggregation DBS0350436 cdk8-/[act15]:myc:cdk8 cdk8 wild type DBS0350437 cdk8-/[act15]:myc:cdk8(D194A) cdk8 decreased spore germination | abolished aggregation DBS0235578 cdk8-/[cdk8]:cdk8 cdk8 wild type DBS0306226 cenB- cenB increased number of centrosomes | aberrant cell separation during cytokinesis | aberrant nuclear envelope morphology | abolished protein localization to microtubule organizing center | aberrant nucleus morphology | aberrant cytokinesis | decreased microtubule nucleation | aberrant centrosome organization DBS0306227 cenB-/[act15]:RFP:cenB cenB wild type DBS0349926 cepC- cepC aberrant mitotic spindle organization | decreased growth rate | aberrant Golgi localization | abolished vegetative growth | aberrant centrosome organization DBS0350265 cepK- cepK decreased protein level | decreased protein localization to nuclear envelope | aberrant chemotaxis to cAMP | decreased growth rate | decreased mound size | decreased vegetative cell size | decreased fruiting body size DBS0302444 cfaD- cfaD aberrant cellular homeostasis | increased cell death | decreased spore germination | aberrant vegetative growth | aberrant cytokinesis | aberrant fruiting body morphogenesis | increased growth rate | decreased sporulation DBS0350010 cfaD-/[act15]:bzpN:GFP bzpN | cfaD abolished negative regulation of vegetative growth DBS0302446 cfaD-/[act15]:cfaD cfaD wild type HO101 chcA- chcA decreased pinocytosis | delayed cell separation during cytokinesis | aberrant cytokinesis | decreased growth rate HO103 chcA- chcA abolished sporulation | abolished cytokinesis | abolished gene expression | delayed aggregation | abolished vegetative growth | aberrant fruiting body morphogenesis DBS0350090 chcA-/[act15]:GFP:ap2a1 ap2a1-1 | ap2a1-2 | chcA increased protein localization DBS0235588 chcA-/[act15]:GFP:mhcA chcA | mhcA decreased positive regulation of GTPase activity DBS0302455 chcA-/[act15]:epnA:GFP chcA | epnA aberrant protein localization to clathrin-coated pit DBS0350091 chcA-/[act15]:gppA:GFP chcA | gppA aberrant protein localization to plasma membrane DBS0235589 chcA-/[cotB]:lacZ chcA aberrant prestalk gene expression | aberrant prespore gene expression DBS0235590 chcA-/[ecmA]:lacZ chcA aberrant prestalk gene expression | aberrant prespore gene expression DBS0235591 chcA-/[ecmB]:lacZ chcA aberrant prestalk gene expression | aberrant prespore gene expression DBS0235592 chcA-/[pspA]:lacZ chcA aberrant prestalk gene expression | aberrant prespore gene expression DBS0350524 chdA- chdA aberrant culmination | aberrant gene expression | decreased chemotaxis to cAMP DBS0350525 chdB- chdB aberrant gene expression | delayed development DBS0350526 chdC- chdC decreased growth rate | development arrests at mound stage | aberrant gene expression | aberrant chromatin assembly | decreased chemotaxis to cAMP DBS0350528 chdC-/[ecmA]:lacZ chdC decreased prestalk cell differentiation DBS0350527 chdC-/[pspA]:lacZ chdC decreased prespore cell differentiation HM1522 chlA- chlA abolished DIF-1 biosynthesis | aberrant slug development | aberrant fruiting body morphogenesis LAS1 chtB- chtB decreased socially cooperative development | increased growth rate CCR2 chtC- chtC decreased socially cooperative development | decreased prestalk A cell differentiation LAS5 chtC-REMI chtC decreased socially cooperative development DBS0305614 chtC-ins chtC decreased socially cooperative development | decreased prestalk A cell differentiation DBS0235601 clc- clc abolished cytokinesis | decreased protein localization to plasma membrane | aberrant hypotonic response | abolished vegetative growth | aberrant fruiting body morphogenesis DBS0235604 clc-/[act15]:GFP-clc(146-194) clc abolished cytokinesis | wild type | aberrant fruiting body morphogenesis DBS0235605 clc-/[act15]:GFP-clc(85-124) clc abolished cytokinesis | wild type | aberrant fruiting body morphogenesis DBS0235607 clc-/[act15]GFP:clc(1-124) clc abolished cytokinesis | wild type | aberrant fruiting body morphogenesis DBS0350408 cldA- cldA decreased gene expression AK1338 clkB- clkB decreased response to Gram-negative bacterium DBS0235608 clmA- clmA aberrant contractile vacuole morphology | aberrant hypotonic response DBS0350473 cln3- cln3 aberrant aggregation | increased protein secretion | aberrant cell separation during cytokinesis | decreased hypotonic response | aberrant cellular process | increased pinocytosis | delayed aggregation | aberrant cell adhesion | aberrant slug migration | aberrant hyperosmotic response | precocious development | increased growth rate | decreased chemotaxis to cAMP | decreased protein secretion DBS0350474 cln3-/[act15]:GFP:cln3 cln3 wild type DBS0351175 cln5- cln5 decreased cell-cell adhesion | aberrant lipid storage | decreased cell-substrate adhesion | decreased chemotaxis to cAMP DBS0235609 cluA- cluA decreased mitochondrial fusion | decreased mitochondrial fission | aberrant cytokinesis | aberrant intracellular distribution of mitochondria | aberrant mitochondrion organization DBS0349875 cluA-/[act15]:cluA cluA wild type DBS0235612 cmfB- cmfB decreased gene expression | abolished aggregation DBS0235613 cnrB- cnrB wild type DBS0350308 cnrF- cnrF aberrant contractile vacuole organization | abolished hypotonic response | decreased contractile vacuole size | aberrant regulation of GTPase activity DBS0350309 cnrF-/[act15]:cnrF:RFP cnrF wild type DBS0350311 cnrF-/cnrF(E623Q/D659Q) cnrF aberrant contractile vacuole organization | abolished hypotonic response | decreased contractile vacuole size | aberrant regulation of GTPase activity DBS0350310 cnrF-/cnrF(R270A) cnrF aberrant contractile vacuole organization | abolished hypotonic response | decreased contractile vacuole size | aberrant regulation of GTPase activity DBS0302655 cnrN- cnrN increased oscillatory cAMP signaling | increased number of mounds | decreased spore germination | increased actin filament polymerization | aberrant cytokinesis | aberrant stream morphology | increased growth rate | abolished positive regulation of chemorepellant activity | decreased sporulation DBS0302656 cnrN-/[act15]:cnrN cnrN wild type HG1770 cnxA- cnxA decreased calcium ion import | aberrant calcium-mediated signaling DBS0235615 cofB- cofB wild type DBS0235616 cofC- cofC-1 wild type DBS0350522 comA- comA aberrant defense response to bacterium | aberrant phagocytosis | aberrant hyperosmotic response DG1016 comB- comB abolished culmination DBS0235618 comC- comC aberrant aggregation | aberrant stream morphology DBS0235619 comD- comD abolished culmination DBS0235620 comE- comE aberrant fruiting body morphogenesis | aberrant sorus color DBS0235621 comF- comF-1 | comF-2 abolished aggregation DBS0235622 comG- comG increased number of tip-organizers | development arrests at mound stage DBS0235623 comH- comH development arrests at mound stage HG1570 corA- corA increased myosin II assembly | aberrant cytokinesis | decreased growth rate | decreased cell motility | aberrant cell morphology HG1571 corA- corA increased myosin II assembly | aberrant cytokinesis | decreased growth rate | decreased cell motility | aberrant cell morphology DBS0351402 corA- corA aberrant actin cytoskeleton organization | aberrant cytokinesis HG1569 corA- corA decreased defense response to Gram-negative bacterium | increased myosin II assembly | aberrant cytokinesis | decreased growth rate | decreased phagocytosis | increased actin filament polymerization | decreased cell motility | aberrant cell morphology | decreased defense response to Gram-positive bacterium DBS0350370 corA- corA decreased defense response to Gram-negative bacterium | decreased gene expression | aberrant chemotaxis to cAMP | aberrant response to cAMP | decreased phagocytosis | aberrant cellular response to extracellular stimulus | decreased establishment of cell polarity | abolished aggregation DBS0351521 corA-/[act15]:FLAG:corA(1-432) corA abolished aggregation DBS0350345 corA-/[act15]:GFP:mhkA corA | mhkA wild type DBS0350346 corA-/[act15]:GFP:mhkB corA | mhkB wild type DBS0350344 corA-/[act15]:GFP:mhkC corA | mhkC decreased catalytic activity | wild type DBS0350343 corA-/[act15]:GFP:pakA(797-1197) corA | pakA wild type DBS0350371 corA-/[act15]:corA corA wild type DBS0350341 corA-/[act15]:corA(I118A/S119A/P121A):GFP corA wild type | aberrant binding | increased myosin II assembly DBS0350851 corA-/aip1- aip1 | corA aberrant endocytosis | aberrant cytokinesis | increased actin filament polymerization | development arrests at mound stage | decreased growth rate | aberrant nucleus morphology | increased vegetative cell size | increased protein level | decreased chemotaxis to cAMP DBS0351412 corA-/mhcA- corA | mhcA aberrant cytokinesis DBS0351413 corA-/piaA- corA | piaA aberrant cytokinesis DBS0305825 corB- corB increased lateral pseudopodium formation | aberrant phagocytosis | decreased growth rate | increased cell-substrate adhesion DBS0349942 cosA- cosA decreased cell motility | decreased fruiting body size | decreased chemotaxis to cAMP | aberrant actin filament organization | increased pseudopodium formation TL55 cotA- cotA decreased spore germination | aberrant spore coat morphology | abolished cellulose binding TL53 cotA-/cotB- cotA | cotB aberrant spore coat morphology TL56 cotA-/cotB-/cotC- cotA | cotB | cotC decreased spore germination | aberrant spore coat morphology | abolished cellulose binding TL57 cotA-/cotB-/cotC- cotA | cotB | cotC aberrant spore coat morphology TL26 cotB- cotB decreased spore germination | aberrant spore coat morphology | abolished cellulose binding TL54 cotB-/cotC- cotB | cotC aberrant spore coat morphology TL52 cotC- cotC aberrant spore coat morphology HW07 cotE(1-235) cotE aberrant spore coat morphology DBS0351045 cox3- cox3 decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant fruiting body morphogenesis | aberrant phototaxis DBS0351538 cpnA-/AX4 cpnA increased contractile vacuole size DBS0238297 cpnA-/NC4A2 cpnA delayed hypotonic response | increased migratory slug size | decreased post-lysosomal vacuole size | increased mound size | aberrant thermotaxis | increased contractile vacuole size | increased exocytosis | decreased growth rate | aberrant cytokinesis | aberrant stalk cell differentiation | development arrests at slug stage | decreased number of post-lysosomal vacuoles | aberrant fruiting body morphogenesis | delayed development | abolished phototaxis DBS0238320 cpnA-/[act15]:GFP:cpnA cpnA delayed hypotonic response | decreased culmination | delayed development DBS0350869 crlA-/AX2 crlA wild type DBS0235627 crlA-/KAX3 crlA delayed development of tipped mound | abolished polyketide metabolic process | increased mound size | decreased spore germination | decreased spore cell differentiation | decreased cell migration to prestalk region | increased growth rate DBS0235628 crlA-/[crlA]:crlA crlA increased mound size DBS0235629 crlB- crlB wild type DBS0235630 crlC- crlC wild type HG1768 crtA- crtA decreased calcium ion import | aberrant calcium-mediated signaling HG1772 crtA-/cnxA- cnxA | crtA decreased calcium ion import | decreased growth rate | delayed response to cAMP | decreased phagocytosis | aberrant calcium-mediated signaling DBS0235633 crtf- crtf abolished sporulation | decreased gene expression | abolished aggregation DBS0351557 cryS- cryS decreased pinocytosis | decreased culmination | decreased phagocytosis | aberrant cytokinesis | decreased growth rate AX2-T10 csaA- csaA decreased cell-cell adhesion | decreased culmination | abolished protein localization to cell-cell contact zone | delayed aggregation | increased cell-substrate adhesion | decreased sporulation TL73 csaA-/csbA-/csbC-/csbC- csaA | csbA | csbB | csbC increased stalk width | aberrant late culminant morphology TL122 csaA-/tgrC1- csaA | tgrC1 abolished calcium-independent cell-cell adhesion TL72 csbA-/csbB-/csbC- csbA | csbB | csbC increased resistance to cisplatin | aberrant cytokinesis | aberrant late culminant morphology WTC127 cshA- cshA development arrests at loose mound stage | decreased phagocytosis | decreased growth rate | delayed aggregation DBS0235634 csn5-KD csn5 decreased growth rate DBS0235624 ctnA- ctnA increased cGMP-mediated signaling | aberrant cellular metabolic process | increased glucose level | decreased protein level | increased mound size | decreased catalytic activity | increased guanylyl cyclase activity | decreased actin filament polymerization | decreased oscillatory cAMP signaling | increased cell-cell adhesion | increased protein level | increased cell motility | decreased myosin II assembly DBS0235636 ctnB- ctnB increased number of mounds | decreased gene expression | decreased fruiting body size DBS0304927 ctnnA- ctnnA wild type DBS0304928 ctnnA-/mhcA- ctnnA | mhcA aberrant cytokinesis DG1071 ctr9- ctr9 aberrant fruiting body morphogenesis DG1058 ctrA- ctrA decreased fruiting body size DBS0350915 ctsD- ctsD aberrant protein modification DBS0235598 ctxA- ctxA aberrant cytokinesis | decreased cell motility | aberrant cell morphology HS1151 ctxA- ctxA aberrant cytokinesis | decreased growth rate | aberrant stream morphology | aberrant cellular response to stress DBS0237568 ctxA-/[RNAi]enlA ctxA | enlA wild type DBS0349922 ctxA-/[act15]:GFP-mhcA ctxA aberrant protein localization to basolateral plasma membrane | aberrant stalk morphogenesis | aberrant development of tipped mound DBS0237536 ctxA-/[act15]:enlA(92-497) ctxA | enlA wild type DBS0235599 ctxA-/ctxB- ctxA | ctxB abolished stream development | aberrant cellular response to fluid shear stress | abolished adenylate cyclase activity | increased lateral pseudopodium formation | aberrant cytokinesis | development arrests at mound stage | aberrant chemotaxis to cAMP | decreased cell motility | aberrant regulation of GTPase activity | aberrant cell morphology | abolished aggregation | aberrant regulation of protein kinase activity | increased bleb assembly DBS0350293 ctxA-/ctxB-/[act15]:GFP:arcA arcA | ctxA | ctxB aberrant protein localization to cell cortex DBS0349972 ctxA-/ctxB-/[act15]:acaA:YFP acaA | ctxA | ctxB aberrant fruiting body morphogenesis DBS0349973 ctxA-/ctxB-/[act15]:carA:YFP carA-1 | carA-2 | ctxA | ctxB abolished stream development | abolished adenylate cyclase activity | development arrests at tight mound stage DBS0235600 ctxB- ctxB aberrant cytokinesis | aberrant stream morphology | aberrant cell morphology DBS0350404 ctxC- ctxC increased pinocytosis | decreased oscillatory cAMP signaling | aberrant stream morphology | decreased chemotaxis to cAMP | increased growth rate | increased phagocytosis DBS0235639 cudA- cudA abolished sporulation | decreased gene expression | development arrests at slug stage | decreased prespore gene expression | abolished stalk cell differentiation DBS0238017 cudA- cudA abolished gene expression DBS0235640 culA- culA increased number of tip-organizers | development arrests at tipped mound stage DBS0235641 culA-/[cotC]:culA culA increased sorus size | decreased stalk length | decreased sporulation DBS0235642 culA-/[ecmA]:culA culA increased sorus size | decreased stalk length DBS0235643 culA-/[pkaC]pkaC culA | pkaC wild type DBS0266745 culB- culB increased number of mound tips | precocious prestalk gene expression | aberrant slug development | decreased fruiting body size | decreased sporulation DBS0266761 culB-/[act15]:pkaC culB | pkaC abolished sporulation | precocious prestalk gene expression | abolished aggregation | abolished prespore gene expression DBS0266760 culB-/pkaR- culB | pkaR abolished sporulation | precocious prestalk gene expression | abolished aggregation | abolished prespore gene expression DBS0235651 cybA- cybA abolished sporulation | aberrant sorocarp development DBS0350641 cynA- cynA aberrant cell motility | decreased actin filament polymerization | aberrant chemotaxis to cAMP | delayed aggregation | aberrant cell morphology DBS0351047 cytB- cytB decreased defense response to Gram-negative bacterium | decreased gene expression | development arrests at mound stage | decreased growth rate | aberrant phototaxis AK108 dagA- dagA abolished gene expression | decreased gene expression | abolished activation of adenylate cyclase activity | abolished aggregation | decreased chemotaxis to cAMP BW4 dagA- dagA abolished positive regulation of chemorepellant activity DBS0235652 dagA-/[act15]:dagA dagA wild type DBS0235560 dagA-/acaA(L394S) acaA | dagA wild type DBS0235653 darA- darA decreased mound size | abolished aggregation DBS0350531 dclre1- dclre1 decreased resistance to bleomycin | decreased double-strand break repair via nonhomologous end joining | aberrant double-strand break repair via homologous recombination DBS0236307 dcsA- dcsA abolished cellulose biosynthesis DG1099 dcsA- dcsA abolished stalk development | abolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis | abolished stalk cell differentiation DG1128 dcsA- dcsA abolished stalk development | abolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis TL127 dcsA- dcsA abolished stalk development | abolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis | abolished stalk cell differentiation | aberrant stalk development TL128 dcsA-/[act15]:dcsA dcsA wild type DBS0351195 dct- dct aberrant chemotaxis to cAMP | increased activation of GTPase activity DBS0349967 dcx-/lis1(D327H) dcx | lis1 abolished aggregation DBS0349804 detA- detA increased mound size | decreased growth rate | delayed development DBS0349807 detA-/[act6]:GFP:detA detA wild type DBS0349816 detA-/[act6]:GFP:detA/[act6]:3xHA:culD culD | detA increased gene expression DBS0349817 detA-/[act6]:GFP:detA/[act6]:3xHA:repE detA | repE increased gene expression DBS0349813 detA-/[cotB]:GFP detA decreased prespore cell differentiation DBS0349811 detA-/[ecm0]:lacZ detA aberrant prestalk O cell differentiation DBS0349812 detA-/[ecmA0]:GFP detA increased prestalk cell differentiation DBS0349808 detA-/[ecmA0]:lacZ detA increased prestalk cell differentiation DBS0349809 detA-/[ecmA]:lacZ detA increased prestalk A cell differentiation DBS0349810 detA-/[ecmB]:lacZ detA delayed development DBS0350392 dgat1- dgat1 aberrant cellular metabolic process | abolished lipid droplet formation | increased sporulation DBS0350393 dgat1-/dgat2- dgat1 | dgat2 abolished lipid droplet formation | decreased growth rate | increased sporulation | aberrant endoplasmic reticulum membrane organization DBS0350394 dgat1-/dgat2-/[act15]:GFP:dgat2 dgat1 | dgat2 wild type DBS0349911 dgcA- dgcA decreased gene expression | development arrests at slug stage | abolished stalk cell differentiation DBS0349917 dgcA-/[act15]:dgcA(1-124):YFP dgcA development arrests at slug stage DBS0349918 dgcA-/[act15]:dgcA(1-273):YFP dgcA development arrests at slug stage DBS0349914 dgcA-/[act15]:dgcA(125-521):YFP dgcA wild type DBS0349915 dgcA-/[act15]:dgcA(274-521):YFP dgcA wild type DBS0349916 dgcA-/[act15]:dgcA(350-521):YFP dgcA development arrests at slug stage DBS0349913 dgcA-/[act15]:dgcA-Ppal:YFP dgcA wild type DBS0349912 dgcA-/[act15]:dgcA:YFP dgcA wild type DBS0235695 dgkA- dgkA decreased spore germination | increased myosin II assembly | aberrant sorocarp development | decreased chemotaxis rate DBS0351179 dgkA- dgkA aberrant cellular metabolic process | increased resistance to valproic acid | aberrant response to lithium AK299 dhkA- dhkA aberrant stalk morphogenesis | increased prestalk gene expression | aberrant gene expression | aberrant fruiting body morphogenesis | increased sporulation | abolished response to biotic stimulus | decreased sporulation DBS0350665 dhkA-/[act15]:dhkA(D2076N) dhkA decreased sporulation DBS0350664 dhkA-/[act15]:dhkA(H1396Q) dhkA decreased sporulation DBS0350666 dhkA-/[act15]:dhkA(H2396Q)/[act15]:dhkA(D2076N) dhkA wild type DBS0235703 dhkA-/[pkaC]:pkaC dhkA | pkaC aberrant stalk morphogenesis TL134 dhkA-/dhkB- dhkA | dhkB abolished sporulation | increased stalk length | decreased stalk width HR49 dhkA-/fbxA- dhkA | fbxA aberrant fruiting body morphogenesis | decreased sporulation | decreased cAMP level HR51 dhkA-/fbxA- dhkA | fbxA aberrant fruiting body morphogenesis | decreased sporulation HR50 dhkA-/fbxA- dhkA | fbxA abolished culmination | decreased sporulation DBS0350663 dhkA-/pkaR- dhkA | pkaR decreased sporulation DBS0350662 dhkA-/regA- dhkA | regA decreased sporulation DBS0235704 dhkB- dhkB precocious spore germination | decreased cAMP level | aberrant sorus color TL135 dhkC- dhkC precocious culmination | decreased spore germination | precocious aggregation | precocious development | precocious gene expression DBS0350855 dhkC- dhkC aberrant chemotaxis to cAMP DBS0350379 dhkD- dhkD abolished stream development | aberrant slug development | aberrant sorocarp development | precocious gene expression | aberrant late culminant morphology DBS0350381 dhkD-/[ecmAO]:lacZ dhkD aberrant prestalk cell differentiation DBS0350382 dhkD-/[ecmB]:lacZ dhkD aberrant prestalk cell differentiation DBS0350383 dhkD-/[pspA]:lacZ dhkD aberrant prespore cell differentiation LAS99 dhkE- dhkE decreased socially cooperative development DBS0351297 dhkI- dhkI-1 | dhkI-2 aberrant chemotaxis to cAMP | delayed aggregation DBS0235710 dhkK- dhkK aberrant slug migration | delayed culmination | delayed gene expression DBS0235712 dhkK-/[act15]:dhkK(D1125N) dhkK aberrant fruiting body morphogenesis DBS0235714 dhkK-/regA- dhkK | regA precocious development DBS0348046 dhkM- dhkM abolished autophagosome organization | aberrant autophagic cell death DBS0348047 dhkM- dhkM abolished autophagosome organization | abolished actin filament depolymerization | abolished cellulose biosynthesis | abolished autophagic cell death DBS0350173 dhkM- dhkM decreased autophagic vacuole organization | delayed development DBS0235719 dia1-/[act6]:trap1 dia1 | trap1 aberrant aggregation | decreased fruiting body size DBS0235895 dimA- dimA increased standing slug length | increased migratory slug size | abolished prestalk cell differentiation | decreased standing slug width | aberrant fruiting body morphogenesis | increased prespore cell differentiation | decreased prestalk O cell differentiation DBS0235899 dimA-/dimB- dimA | dimB increased migratory slug size | increased standing slug length | aberrant chemotaxis to cAMP | decreased standing slug width DBS0235901 dimB- dimB decreased prestalk B cell differentiation | abolished response to DIF-1 | increased gene expression | aberrant prespore gene expression | aberrant chemotaxis to cAMP DBS0235903 dimB-/[act15]:dimA:GFP dimA | dimB abolished protein localization to nucleus DBS0235904 dimB-/[act15]:dimB:GFP dimB wild type DBS0349992 dimB-/[btg]:lacZ btg | dimB increased gene expression DBS0235902 dimB-/[cotB]:lacZ dimB increased prespore cell differentiation DBS0350573 dimB-/[dimB]:dimB(S590A) dimB wild type DBS0235906 dimB-/[ecmAO]:lacZ dimB decreased prestalk O cell differentiation DBS0349974 dimB-/[ecmB]:lacZ dimB abolished prestalk gene expression DBS0235907 dimB-/[ecmO]:lacZ dimB aberrant prestalk cell differentiation DBS0350495 dio3- dio3 decreased cell-cell adhesion | aberrant aggregation | decreased gene expression | decreased growth rate | decreased prespore cell differentiation | decreased chemotaxis to folate | increased prestalk cell differentiation | decreased cAMP level | decreased phototaxis DBS0350496 dio3-/[act15]:GFP:dio3 dio3 wild type DBS0304919 dlpA- dlpA aberrant cell separation during cytokinesis | aberrant cytokinesis | decreased growth rate | increased actin filament depolymerization | increased vegetative cell size | decreased protein localization | abolished protein localization to cleavage furrow | aberrant actin filament organization DBS0351395 dlpA-/dlpB- dlpA | dlpB aberrant cytokinesis DBS0304920 dlpB- dlpB aberrant cell separation during cytokinesis | aberrant cytokinesis | decreased growth rate | increased vegetative cell size | abolished protein localization to cleavage furrow DBS0304921 dlpC- dlpC aberrant cytokinesis DBS0235913 dmpA- dmpA aberrant stream morphology | aberrant fruiting body morphogenesis | delayed development | decreased stalk cell differentiation | decreased sporulation | aberrant sorus color HM1030 dmtA- dmtA delayed development of tipped mound | abolished DIF-1 biosynthesis | decreased outer basal disc size | wild type | abolished prestalk O cell differentiation | decreased standing slug width | decreased lower cup size | decreased prestalk gene expression | aberrant vacuole organization | aberrant fruiting body morphogenesis | delayed development | decreased prestalk O cell differentiation | decreased prestalk cell differentiation DBS0350410 dmtA-/[act15]:dmtA dmtA wild type DBS0349975 dmtA-/[dimB]:dimB dimB | dmtA decreased prestalk B cell differentiation HM1196 dmtA-/stlA- dmtA | stlB decreased outer basal disc size | decreased prestalk O cell differentiation DBS0235914 dnapkcs- dnapkcs decreased resistance to bleomycin | decreased double-strand break repair via nonhomologous end joining DBS0266875 dnapkcs-/GFP:pcna dnapkcs | pcna aberrant response to bleomycin DBS0350561 dnapkcs-/adprt2- adprt2 | dnapkcs decreased resistance to phleomycin | decreased resistance to cisplatin DBS0351060 dnapkcs-/exo1- dnapkcs | exo1 decreased resistance to phleomycin DBS0235915 dng1- dng1 decreased growth rate | delayed aggregation DBS0235917 dnmA- dnmA decreased DNA methylation on cytosine DBS0235916 dnmA- dnmA decreased DNA methylation on cytosine | aberrant late culminant morphology | aberrant sorus color | decreased sporulation DBS0350457 docA- docA decreased chemotaxis to cAMP DG2015 docA- docA development arrests at mound stage LAS32 docA- docA decreased socially cooperative development DBS0350458 docD- docD decreased cell motility | decreased chemotaxis to cAMP DBS0350459 docD-/docA- docA | docD aberrant fruiting body morphogenesis | delayed development | decreased chemotaxis to cAMP DBS0235920 dokA- dokA aberrant hyperosmotic response | aberrant sorus color | decreased sporulation DBS0349789 dotA- dotA aberrant response to UV | decreased growth rate | decreased spore size | delayed development | abolished histone H3-K79 methylation HAD172 dpoA- dpoA increased gene expression | aberrant sorocarp development HAD200 dpoA- dpoA aberrant sorocarp development HAD201 dpoA- dpoA aberrant sorocarp development HAD202 dpoA- dpoA aberrant sorocarp development HAD203 dpoA- dpoA aberrant sorocarp development HAD205 dpoA-/gskA- dpoA | gskA aberrant sorocarp development HM1467 drcA- drcA abolished catalytic activity DBS0238474 drkC- drkC decreased phagocytosis | decreased phagolysosome formation DBS0238511 drkC-/[act15]:drkC(1-497):YFP drkC decreased phagocytosis DBS0238513 drkC-/[act15]:drkC(K518R):YFP drkC decreased phagocytosis DBS0238475 drkC-/[act15]:drkC:YFP drkC wild type DBS0235922 drnA- drnA-1 decreased gene expression DBS0350174 drnB- drnB abolished pre-miRNA processing DBS0350218 drnB-/[act15]:pre-miRNA drnB abolished pre-miRNA processing DBS0350210 drnB-/[act6]:lacZ/[RNAi]lacZ drnB abolished production of siRNA involved in RNA interference | abolished transitive RNA interference DBS0235924 dscA- dscA-1 | dscA-2 aberrant cell morphology DBS0350775 dscA- dcsA decreased cell motility DBS0302609 dsgg(1-571:581-733) dsgg aberrant contractile vacuole organization DBS0302608 dsgg(1-571:581-733)/dsgg- dsgg aberrant contractile vacuole organization | aberrant cellular localization DBS0302597 dsgg- dsgg aberrant contractile vacuole organization | aberrant hypotonic response DBS0302603 dsgg-/GFP:dsgg dsgg wild type DBS0302602 dsgg-/OE]:dsgg(Delta-Fbox) dsgg wild type DBS0302606 dsgg-/[OE]:GFP:lvsD dsgg | lvsD wild type DBS0302599 dsgg-/[OE]:dsgg dsgg wild type DBS0302601 dsgg-/[OE]:dsgg(Q551A) dsgg aberrant contractile vacuole organization DBS0302600 dsgg-/[OE]:dsggR515A) dsgg aberrant contractile vacuole organization DBS0302607 dsgg-/[OE]:lvsA dsgg | lvsA aberrant contractile vacuole organization DBS0302611 dsgg-/[OE]:phgA dsgg | phgA aberrant contractile vacuole organization DBS0302678 dsgg-/[OE]:rab8A dsgg | rab8A aberrant contractile vacuole organization DBS0302604 dsgg-/lvsA- dsgg | lvsA wild type DBS0302605 dsgg-/lvsD- dsgg | lvsD aberrant contractile vacuole organization DBS0351070 dspA- dspA delayed aggregation | increased cell-substrate adhesion | decreased cell motility | increased protein kinase activation DBS0235925 dstA- dstA abolished gene expression | increased gene expression | aberrant prestalk gene expression | abolished cell migration to prestalk region | decreased gene expression | delayed aggregation | decreased prestalk gene expression | decreased cell motility | abolished stalk cell differentiation | aberrant fruiting body morphogenesis DBS0235926 dstA- dstA aberrant prestalk gene expression | abolished cell migration to prestalk region | delayed aggregation | decreased cell motility | abolished stalk cell differentiation | aberrant fruiting body morphogenesis DBS0238237 dstA-/GFP:dstA(237-707):ORF+ dstA abolished culmination | decreased stalk length DBS0238236 dstA-/GFP:dstA(237-707):ORF+/[OE]dutA(751-1322) dstA | dutA decreased stalk length DBS0252824 dstA-/GFP:dstA(237-707):ORF+/[act15]:2C 2C | dstA aberrant fruiting body morphogenesis DBS0252823 dstA-/GFP:dstA(237-707):ORF+/[act15]:7E 7E | dstA | hssB wild type DBS0252826 dstA-/GFP:dstA(237-707):ORF+/[act15]:DDB_G0276165 DDB_G0276165 | dstA aberrant fruiting body morphogenesis DBS0252825 dstA-/GFP:dstA(237-707):ORF+/[act15]:DDB_G0282325 DDB_G0282325 | dstA aberrant fruiting body morphogenesis DBS0252816 dstA-/GFP:dstA(237-707):ORF+/[act15]:hssA dstA | hssA wild type DBS0252822 dstA-/GFP:dstA(237-707):ORF+/[act15]:hssB dstA | hssB wild type DBS0235928 dstA-/[act15]:dstA dstA wild type DBS0235929 dstA-/[cprB]:dstA dstA wild type DBS0235930 dstA-/[ecmAO]:dstA dstA wild type DBS0235927 dstA-/dstB- dstA | dstB wild type DBS0235931 dstB- dstB decreased gene expression | increased gene expression | decreased growth rate DBS0235933 dstB-/[act15]:dstB dstB wild type DBS0235934 dstB-/[act15]:dstB(L1025R) dstB wild type DBS0235935 dstB-/[act15]:dstB(Y1143F) dstB wild type DBS0235932 dstB-/dstC- dstB | dstC wild type DBS0238125 dstC- dstC abolished gene expression | aberrant response to cation stress | aberrant response to osmotic stress DBS0350425 dstC- dstC aberrant protein phosphorylation DBS0235937 dtfA- dtfA delayed development of tipped mound | decreased cell-cell adhesion | aberrant cytokinesis | aberrant cell migration to prestalk region | aberrant fruiting body morphogenesis DBS0350500 dupA- dupA increased defense response to Gram-negative bacterium | abolished aggregation DBS0350502 dupA- dupA increased defense response to Gram-negative bacterium DBS0238234 dutA- dutA wild type DBS0235939 dwwA- dwwA aberrant cytokinesis | aberrant actin filament organization | aberrant cell morphology DBS0350411 dydA- dydA increased myosin II assembly | increased actin filament polymerization | increased protein localization to plasma membrane | decreased chemotaxis to cAMP DBS0350414 dydA-/dydA(1-278:501-1211) dydA decreased protein localization to cell cortex | increased myosin II assembly | increased actin filament polymerization | aberrant chemotaxis to cAMP DBS0350415 dydA-/dydA(1-586:703-1211) dydA decreased protein localization to cell cortex | decreased chemotaxis to cAMP DBS0350060 dymA- dymA decreased protein localization to cleavage furrow | aberrant cell separation during cytokinesis | decreased growth rate | increased vegetative cell size | aberrant actin filament organization DBS0347874 dymA- dymA decreased pinocytosis | aberrant cell separation during cytokinesis | aberrant mitochondrion morphology | decreased phagolysosome size | increased basal disc size | decreased growth rate | aberrant nucleus morphology | increased vegetative cell size | aberrant endosome morphology | aberrant phagosome maturation | delayed development | aberrant stalk development | aberrant fruiting body morphogenesis | decreased establishment of cell polarity | aberrant pseudopodium formation | abolished phagosome acidification | increased phagocytosis | aberrant intracellular distribution of mitochondria DBS0349839 dymA-/[dymA]:dymA dymA wild type DBS0350803 dymA-/ehd- dymA | ehd aberrant phagosome maturation | decreased protein processing in phagocytic vesicle DBS0347875 dymB- dymB decreased growth rate | aberrant hypotonic response | increased cell-cell adhesion | increased cell-substrate adhesion | decreased vegetative cell size | decreased catalase activity | aberrant actin filament organization | increased growth rate | increased phagocytosis DBS0235940 eb1- eb1 aberrant mitosis | aberrant cytokinesis | aberrant protein localization HJW117 ecmA- ecmA increased standing slug length | decreased standing slug width | decreased slime trail HJW01 ecmB- ecmB wild type HJW03 ecmB- ecmB wild type DBS0235944 ecmF- ecmF wild type DBS0350904 efbA- efbA aberrant cytokinesis | delayed development DBS0235945 egeA- egeA decreased activation of adenylate cyclase activity | decreased gene expression | abolished aggregation DBS0350520 egeA-/[unk]:YFP:carA carA-1 | carA-2 | egeA development arrests at mound stage DBS0350521 egeA-/[unk]:pkaC egeA | pkaC decreased gene expression | abolished aggregation DBS0235946 egeB- egeB development arrests at mound stage DBS0350802 ehd- ehd aberrant endosome morphology | aberrant phagosome maturation | decreased protein processing in phagocytic vesicle DBS0350804 ehd-/[act15]:dymA:GFP dymA | ehd aberrant phagosome maturation | decreased protein processing in phagocytic vesicle DBS0351166 ei24- ei24 aberrant aggregation | decreased spore germination | increased gene expression | decreased gene expression | decreased growth rate | aberrant cell cycle | delayed development | decreased chemotaxis to cAMP | decreased fruiting body size | decreased cAMP level | decreased sporulation DBS0302590 elmoA- elmoA increased protein localization to pseudopodium | decreased culmination | abolished establishment of cell polarity | increased actin filament polymerization | decreased cell motility | delayed development | increased pseudopodium formation | increased phagocytosis DBS0302598 elmoA-/[act15]:elmoA(1-903/959-977):GFP elmoA decreased cell motility | increased phagocytosis DBS0302591 elmoA-/[act15]:elmoA:GFP elmoA wild type DBS0350065 elmoE- elmoE decreased culmination | decreased actin filament polymerization at leading edge | decreased chemotaxis to cAMP DBS0351604 elp3- elp3 decreased protein level DBS0302448 epnA- epnA aberrant spore morphology | decreased spore germination | abolished protein localization to cell cortex | aberrant cytokinesis | abolished protein localization to plasma membrane | aberrant actin cytoskeleton organization | abolished protein phosphorylation DBS0302457 epnA-/[act15]:GFP:epnA(253-677) epnA aberrant spore morphology | abolished protein localization to plasma membrane | abolished protein localization to clathrin-coated pit DBS0302456 epnA-/[act15]:epnA(1-133):GFP epnA aberrant localization to coated pits DBS0302474 epnA-/[act15]:epnA(R65A/K78A):GFP epnA aberrant spore morphology | abolished protein localization to plasma membrane | abolished phosphatidylinositol-4,5-bisphosphate binding | abolished protein localization to clathrin-coated pit | abolished protein phosphorylation DBS0302475 epnA-/[act15]:epnA(T107A):GFP epnA aberrant spore morphology | abolished protein localization to plasma membrane DBS0302454 epnA-/[act15]:epnA:GFP epnA wild type DBS0235947 eppA- eppA decreased growth rate | delayed development | decreased chemotaxis to folate | decreased chemotaxis to cAMP | decreased cAMP level DBS0235948 eppA-/[act6]:myc:eppA eppA wild type DBS0350028 erkA- erkA decreased mound size | decreased chemotaxis to cAMP DBS0350622 erkA- erkA aberrant development of tipped mound | aberrant stream morphology | abolished protein kinase activation | aberrant cellular response to extracellular stimulus | abolished positive regulation of chemorepellant activity DBS0350623 erkA- erkA decreased mound size | precocious development DBS0350681 erkA-/[act15]:gpaE erkA | gpaE wild type DBS0350029 erkA-/[act15]:mekA:FLAG erkA | mekA increased protein localization to cell cortex DBS0351474 erkA-/regA- erkA | regA decreased mound size | aberrant fruiting body morphogenesis DBS0351296 erkB- erkB abolished chemotaxis to folate | increased actin filament polymerization | abolished protein phosphorylation HS174 erkB- erkB decreased catalytic activity | aberrant phagocytosis | decreased cell motility | decreased prespore gene expression | decreased prestalk gene expression | aberrant sorocarp development | decreased chemotaxis to folate | abolished aggregation | decreased chemotaxis to cAMP | aberrant cell morphology | decreased sporulation AK240 erkB- erkB abolished aggregation | decreased sporulation DBS0350606 erkB- erkB decreased prespore cell differentiation DBS0350683 erkB-/[ecmA]:lacZ erkB aberrant cell migration to prestalk region DBS0350682 erkB-/[unk]:erkB(P140S) erkB abolished sporulation DBS0235949 erkB-/regA- erkB | regA increased oscillatory cAMP signaling | abolished aggregation DBS0350530 exo1- exo1 decreased resistance to bleomycin | decreased double-strand break repair via homologous recombination DBS0304864 expl7- expl7 wild type DBS0235951 fadA- fadA increased cellular thermotolerance DBS0235952 fadB- fadB wild type DBS0350240 fam21- fam21 abolished exocytosis | aberrant vegetative growth | decreased protein localization to post-lysosomal vacuole | decreased protein processing in phagocytic vesicle | aberrant autophagic cell death | aberrant phagosome maturation | aberrant lysosome organization DBS0236034 fam45- fam45 wild type DBS0236040 fam91- fam91 wild type DBS0350717 far1- far1 aberrant binding | decreased actin filament polymerization | aberrant defense response to bacterium | aberrant macropinocytosis | decreased growth rate | aberrant phagocytosis | aberrant chemotaxis | decreased engulfment during phagocytosis | decreased chemotaxis to folate | decreased protein kinase activation | decreased folic acid binding | aberrant signal transduction DBS0351093 far1- far1 abolished chemotaxis to folate DBS0351545 fatA- fatA aberrant lipid storage | decreased phagocytosis DBS0235953 fbxA- fbxA decreased sporulation HR6 fbxA- fbxA decreased socially cooperative development HR42 fbxA-/[act15]:myc:fbxA fbxA abolished culmination | decreased sporulation DBS0235954 fbxA-/[ecmA]:GFP(S65T) fbxA increased prespore cell differentiation HR46 fbxA-/regA- fbxA | regA aberrant fruiting body morphogenesis | decreased sporulation HR48 fbxA-/regA- fbxA | regA aberrant fruiting body morphogenesis | decreased sporulation DBS0235956 fbxA1- fbxA development arrests at slug stage | aberrant fruiting body morphogenesis | increased slug migration | delayed culmination DBS0235957 fbxA2- fbxA development arrests at slug stage | aberrant fruiting body morphogenesis | increased slug migration | delayed culmination DBS0235958 fbxA3- fbxA development arrests at slug stage | aberrant fruiting body morphogenesis | increased slug migration | delayed culmination DG1148 fcpA- fcpA aberrant fruiting body morphogenesis DBS0235960 fcsA- fcsA decreased fatty acid level | decreased lipid droplet formation | increased sporulation DBS0350128 fcsB- fcsB decreased catalytic activity | decreased phagocytosis DBS0350129 fcsB-/fcsA- fcsA | fcsB decreased catalytic activity | decreased growth rate | delayed development DBS0350336 febA- febA wild type DBS0350953 fhbA- fhbA increased vegetative cell size | aberrant cellular response to stress DBS0350955 fhbA-/fhbB- fhbA | fhbB aberrant cellular response to stress DBS0350954 fhbB- fhbB increased vegetative cell size | aberrant cellular response to stress DBS0235961 fimA- fimA decreased vegetative cell size HM1253 fncD2- fncD2 decreased resistance to cisplatin HM1351 fncD2-/rev3- fncD2 | rev3 decreased resistance to cisplatin HM1405 fncD2-/xpf- fncD2 | xpf decreased resistance to cisplatin HM1416 fncE- fncE decreased resistance to cisplatin HM1356 fncI- fncI decreased resistance to cisplatin HM1302 fncL- fncL decreased resistance to cisplatin HM1407 fncM- fncM decreased resistance to cisplatin DBS0235966 forA- forA wild type DBS0350667 forA- forA aberrant cellular response to fluid shear stress | decreased cell motility | increased cell motility DBS0350669 forA-/[act15]:GFP:mhcA forA | mhcA aberrant bleb assembly DBS0235967 forA-/forB- forA | forB wild type DBS0235968 forB- forB wild type DBS0235969 forC- forC aberrant culmination | aberrant fruiting body morphogenesis | development arrests at tipped mound stage DBS0350280 forC- forC delayed aggregation | aberrant sorocarp development | decreased chemotaxis to cAMP | decreased sporulation | abolished slug development | delayed gene expression DBS0304905 forC-/[act15]:GFP:forC forC wild type DBS0351307 forE-/forA-/forH- forA | forE | forH aberrant cortical actin cytoskeleton organization | aberrant cytokinesis | aberrant sorocarp development | decreased cell motility | aberrant cell morphology DBS0350287 forF- forF decreased fruiting body size | aberrant phototaxis | increased chemotaxis rate DBS0350835 forG- forG decreased growth rate | decreased phagocytosis | aberrant actin cytoskeleton organization | decreased macropinocytosis | aberrant actin filament organization DBS0235970 forH- forH decreased cell-substrate adhesion | decreased chemotaxis rate | increased cell motility | aberrant pseudopodium formation | aberrant cell morphology | decreased filopodium formation DBS0235971 forH-/[act15]:GFP:forH forH increased filopodium formation | decreased cell motility | increased cell-substrate adhesion HW440 fpaA(P143A) fpaA delayed aggregation | increased response to hypoxia HW435 fpaB-/AX2 fpaB-1 | fpaB-2 decreased response to hypoxia | increased culmination | increased stalk length DBS0302506 frmA- frmA delayed aggregation | decreased cell motility | decreased mound size | increased cell-substrate adhesion | aberrant cell morphology DBS0304440 frmA-/[unk]:GFP frmA decreased gene expression | aberrant sorocarp development | increased cell-cell adhesion | delayed development | abolished phototaxis DBS0302507 frmA-/[unk]:frmA-HA frmA wild type DBS0350983 frmB- frmB aberrant aggregation | increased mound size | decreased cell-substrate adhesion | increased fruiting body size DBS0350232 fscE- fscE aberrant positive regulation of chemorepellant activity | decreased growth rate | aberrant cytokinesis DBS0350228 fslA- fslA aberrant cytokinesis DBS0350230 fslB- fslB aberrant positive regulation of chemorepellant activity | decreased catalytic activity | aberrant cytokinesis DBS0350229 fslK- fslK decreased catalytic activity | aberrant vegetative growth | aberrant cytokinesis DBS0350252 fspA- fspA decreased gene expression | aberrant chemotaxis to folate | aberrant vegetative growth DBS0350253 fspA-/[unk]:fspA:FLAG fspA wild type DBS0235976 fszA- fszA decreased number of mitochondria | aberrant mitochondrion morphology DBS0235978 fszA-/fszB- fszA | fszB aberrant mitochondrion morphology DBS0235980 fszB- fszB aberrant mitochondrion morphology | decreased number of mitochondria | decreased growth rate DG1066 fut1- fut1 aberrant fruiting body morphogenesis DBS0305025 gabT- gabT precocious development | decreased sporulation DBS0305026 gabT-[pkaC]:pkaC gabT | pkaC aberrant protein secretion DBS0351298 gacG- gacG increased chemotaxis to folate | increased actin filament polymerization at leading edge DBS0351318 gacG- gacG aberrant macropinocytosis | abolished vegetative growth DBS0351299 gacH- gacH aberrant chemotaxis to cAMP DG1094 gacT- gacT aberrant fruiting body morphogenesis DBS0235989 gadA- gadA decreased spore cell differentiation | decreased sporulation DBS0350071 gadA- gadA decreased spore germination DBS0350077 gadA-/gadB- gadA | gadB delayed aggregation DBS0350072 gadB- gadB delayed aggregation DBS0350963 gapA- gapA aberrant cell separation during cytokinesis DBS0349924 gapA- gapA decreased actin filament bundle assembly DBS0350399 gapA- gapA decreased protein localization to cleavage furrow | increased myosin II assembly | increased lateral pseudopodium formation | aberrant mitotic spindle organization | increased actin filament polymerization | decreased chemotaxis to cAMP | aberrant cellular response to stress DBS0350403 gapA-/iqgC- gapA | iqgC decreased protein kinase activation | decreased chemotaxis to cAMP TL198 gbfA- gbfA abolished gene expression | development arrests at mound stage DBS0302689 gbfA- gbfA aberrant oscillatory cAMP signaling DBS0305094 gbfA- gbfA abolished autophagosome organization | abolished autophagic cell death DBS0235994 gbpC- gbpC decreased protein kinase activation | decreased fruiting body size DBS0235995 gbpC- gbpC aberrant chemotaxis to cAMP | aberrant myosin II filament organization | decreased chemotaxis rate | aberrant cyclic nucleotide binding | aberrant cell morphology | decreased establishment of cell polarity | decreased fruiting body size DBS0302680 gbpC- gbpC abolished protein localization to nucleus | decreased mound size | abolished protein phosphorylation DBS0350881 gbpC- gbpC aberrant cyclic nucleotide binding DBS0304912 gbpC-/[act15]:gbpC gbpC wild type DBS0304917 gbpC-/[act15]:gbpC(1-1698:2005-2631) gbpC decreased chemotaxis to cAMP DBS0349868 gbpC-/[act15]:gbpC(1-2331:2470-2631):GFP gbpC aberrant stream morphology | decreased chemotaxis to cAMP DBS0304918 gbpC-/[act15]:gbpC(311-2631) gbpC decreased chemotaxis to cAMP DBS0304916 gbpC-/[act15]:gbpC(F1892A) gbpC decreased chemotaxis to cAMP DBS0304915 gbpC-/[act15]:gbpC(F2082A/E2084A/F2564A/E2566A) gbpC decreased chemotaxis to cAMP DBS0304913 gbpC-/[act15]:gbpC(K342N) gbpC decreased chemotaxis to cAMP DBS0304914 gbpC-/[act15]:gbpC(K905W) gbpC decreased chemotaxis to cAMP DBS0235996 gbpC-/gbpD- gbpC | gbpD delayed aggregation | decreased chemotaxis rate | decreased establishment of cell polarity | increased bleb assembly DBS0235997 gbpD- gbpD increased establishment of cell polarity | decreased cell-substrate adhesion | decreased lateral pseudopodium formation | increased chemotaxis rate DBS0235998 gbpD-/[act15]:gbpD gbpD increased lateral pseudopodium formation | increased cell-substrate adhesion | decreased chemotaxis rate | aberrant actin filament organization | abolished aggregation DG1120 gbqA- gbqA aberrant fruiting body morphogenesis DBS0350119 gcA- gcA decreased guanylyl cyclase activity DBS0236000 gca-/sgcA- gcA | sgcA decreased protein kinase activation DBS0302679 gca-/sgcA- gcA | sgcA increased lateral pseudopodium formation | aberrant activation of GTPase activity | aberrant chemotaxis to cAMP | aberrant taxis | aberrant stream morphology | decreased mound size | decreased chemotaxis rate | decreased fruiting body size DBS0236002 gcsA- gcsA abolished sporulation | aberrant cellular metabolic process | decreased gene expression | increased gene expression | development arrests at mound stage | abolished vegetative growth | mitotic G1 phase arrest | abolished aggregation | abolished prespore gene expression DBS0350387 gcsA-/[act15]:carA carA-1 | carA-2 | gcsA abolished aggregation DBS0236003 gcsA-/[act15]:gcsA gcsA decreased spore germination | development arrests at mound stage DBS0350388 gcsA-/[act15]:yakA gcsA | yakA wild type DBS0236004 gdt1- gdt1 increased gene expression | decreased growth rate | precocious aggregation DBS0237190 gdt1-/[act15]:pkaR(G135E/G261A) gdt1 | pkaR increased gene expression | abolished aggregation DBS0236095 gdt1-/gpaB- gdt1 | gpaB increased gene expression | abolished aggregation DBS0236006 gdt2- gdt2 increased gene expression | precocious aggregation DBS0252697 gefA- gefA decreased taxis RI19 gefA- gefA decreased actin filament polymerization | decreased gene expression | decreased activation of GTPase activity | abolished activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased chemotaxis rate | abolished aggregation | increased protein kinase activation JB10 gefA- gefA abolished aggregation DBS0350821 gefA- gefA decreased actin filament polymerization | decreased activation of GTPase activity | aberrant chemotaxis to cAMP | decreased protein kinase activation | abolished aggregation DBS0350449 gefA-/[dscB]:rasG(S17N) gefA | rasG decreased actin filament polymerization | decreased activation of GTPase activity | aberrant chemotaxis to cAMP | decreased protein kinase activation DBS0351451 gefB-/AX2 gefB wild type DBS0236009 gefB-/AX3 gefB abolished pinocytosis | delayed aggregation | increased actin filament polymerization | decreased phagocytosis | decreased growth rate | decreased mound size | abolished vegetative growth | aberrant fruiting body morphogenesis | aberrant cell morphology | increased bleb assembly | aberrant cytoskeleton organization DBS0236010 gefB-/rasS- gefB | rasS decreased phagocytosis | increased cell motility DBS0236868 gefC- gefC wild type DBS0236869 (DBS0235543) gefD- gefD wild type | aberrant activation of GTPase activity DBS0236870 gefE- gefE aberrant thermotaxis | aberrant activation of GTPase activity | aberrant phototaxis DBS0350569 gefE- gefE decreased activation of GTPase activity | increased gene expression | decreased response to DIF-1 | increased prespore cell differentiation DBS0351462 gefE-/uduB- gefE | uduB wild type DBS0351450 gefF:GFP gefF decreased macropinocytosis DBS0350822 gefH- gefH decreased actin filament polymerization | decreased activation of GTPase activity | aberrant chemotaxis to cAMP | delayed development | decreased protein kinase activation DBS0350823 gefH-/gefA- gefA | gefH decreased actin filament polymerization | aberrant chemotaxis to cAMP | abolished activation of GTPase activity | decreased protein kinase activation | abolished aggregation DBS0236012 gefK- gefK wild type DBS0351618 gefK-/gacL- gacL | gefK decreased response to Gram-negative bacterium | aberrant vegetative growth DBS0236871 gefL- gefL aberrant thermotaxis | aberrant phototaxis HSB61 gefM- gefM increased cGMP-mediated signaling | decreased lateral pseudopodium retraction | aberrant activation of adenylate cyclase activity | development arrests at mound stage | decreased chemotaxis rate DBS0304968 gefQ- gefQ decreased positive regulation of GTPase activity | increased number of mound tips | increased myosin II assembly | increased lateral pseudopodium formation | abolished cell migration to prestalk region | abolished guanyl-nucleotide exchange factor activity | decreased growth rate | decreased fruiting body size | abolished phototaxis DBS0304985 gefQ-/[act15]:GFP:gefQ(172-654) gefQ abolished guanyl-nucleotide exchange factor activity | decreased phototaxis DBS0304986 gefQ-/[act15]:GFP:gefQ(910-1298) gefQ decreased phototaxis DBS0236014 gefR- gefR wild type | decreased activation of GTPase activity DBS0349892 gefS- gefS wild type DBS0349904 gemA- gemA decreased ATP level | decreased growth rate DBS0350811 gflB- gflB decreased culmination | decreased protein localization to cell cortex | aberrant G protein-coupled receptor signaling | delayed aggregation | decreased mound size | decreased chemotaxis to cAMP | aberrant protein localization to plasma membrane | increased actin filament polymerization at leading edge | decreased myosin II assembly HA201 gflB- gflB decreased phagocytosis | aberrant mitotic actomyosin contractile ring contraction | increased actin filament polymerization | decreased macropinocytosis | increased substrate adhesion-dependent cell spreading DBS0350814 gflB-/[act15]:GFP:gflB(380-1601,T1180E) gflB decreased chemotaxis to cAMP DG1109 ggtA- ggtA aberrant fruiting body morphogenesis DBS0351210 gip1- gip1 decreased protein localization to plasma membrane | aberrant chemotaxis to cAMP DBS0266723 glcS-/DH1 glcS aberrant stalk morphogenesis | decreased glycogen level | decreased spore size | decreased fruiting body size DBS0266765 glcS-/HMX glcS abolished cellulose biosynthesis | decreased autophagic vacuole organization | aberrant cell morphology DBS0350514 glk- glk decreased defense response to Gram-negative bacterium DBS0351101 glkA- glkA aberrant aggregation | decreased protein localization to cell cortex | decreased protein level | decreased chemotaxis to cAMP | decreased myosin II assembly | increased activation of GTPase activity | increased protein kinase activation DBS0236078 glpD- glpD aberrant glycogen metabolism | aberrant regulation of catalytic activity HL250 gmd(G108D) gmd decreased spore germination | decreased growth rate DBS0236079 gmsA- gmsA decreased sexual fusion DBS0236080 gmsA- gmsA decreased sexual fusion HW503 gnt1(1-253/H104D) gnt1 aberrant stalk morphogenesis | development arrests at slug stage | increased response to hypoxia DBS0238384 gnt14- gnt14 wild type DBS0238382 gnt15- gnt15 decreased gene expression | decreased growth rate | increased calcium-independent cell-cell adhesion | abolished aggregation | abolished culmination DBS0238383 gnt15- gnt15 decreased gene expression | decreased growth rate | increased calcium-independent cell-cell adhesion | abolished aggregation | abolished culmination DBS0238390 gnt15-/[act15]:FLAG:gnt15 gnt15 wild type DBS0238391 gnt15-/[act15]:FLAG:gnt15 gnt15 wild type DBS0236081 gnt2- gnt2 abolished catalytic activity | abolished protein modification DBS0236082 gol- gol increased resistance to cisplatin DBS0235414 gp130- gp130 decreased response to Gram-positive bacterium | decreased cell-substrate adhesion | delayed development | increased growth rate DBS0236087 gpaA- gpaA aberrant aggregation | increased stalk length | aberrant response to cAMP | decreased stalk width JH131 gpaA- gpaA aberrant cellular homeostasis | wild type | increased growth rate DBS0236091 gpaA-/[ecmB]:lacZ gpaA decreased prestalk gene expression DBS0236092 gpaA-/[gpaA]:gpaA(G45V) gpaA delayed development DBS0236093 gpaA-/[gpaA]:gpaA(Q206L) gpaA increased basal disc size DBS0238605 gpaA-/rpkA- gpaA | rpkA delayed aggregation | abolished aggregation DBS0236575 gpaB- gpaB decreased response to cAMP | abolished activation of GTPase activity | aberrant phagocytosis | decreased cGMP-mediated signaling | decreased protein kinase activation | abolished aggregation | abolished chemotaxis to cAMP JH104 gpaB- gpaB decreased gene expression | decreased activation of GTPase activity | abolished activation of adenylate cyclase activity | abolished aggregation | abolished chemotaxis to cAMP JM1 gpaB-/[OE]:carA carA-1 | carA-2 | gpaB aberrant calcium-mediated signaling DBS0236096 gpaB-/[act15]:gpaB gpaB abolished aggregation DBS0266942 gpaB-/[act15]:gpaB gpaB delayed aggregation DBS0266939 gpaB-/[act15]:gpaB(1-345):gpaD(337-345) gpaB | gpaD abolished aggregation DBS0351103 gpaB-/[act15]:gpaB(C4A) gpaB abolished protein localization to plasma membrane | decreased cGMP-mediated signaling | abolished aggregation DBS0237137 gpaB-/[act15]:gpaB(D154V) gpaB aberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate DBS0237138 gpaB-/[act15]:gpaB(E190G) gpaB aberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling DBS0351105 gpaB-/[act15]:gpaB(G207A) gpaB abolished protein localization to plasma membrane DBS0351104 gpaB-/[act15]:gpaB(G2A) gpaB abolished protein localization to plasma membrane DBS0237139 gpaB-/[act15]:gpaB(I104S) gpaB aberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate DBS0237140 gpaB-/[act15]:gpaB(L110S) gpaB aberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate DBS0237141 gpaB-/[act15]:gpaB(L76P) gpaB abolished aggregation DBS0237142 gpaB-/[act15]:gpaB(N74D) gpaB decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate | abolished aggregation DBS0237143 gpaB-/[act15]:gpaB(R64G) gpaB decreased chemotaxis rate | abolished aggregation DBS0237144 gpaB-/[act15]:gpaB(S155P) gpaB decreased chemotaxis rate | abolished aggregation DBS0351217 gpaB-/[act15]:gpaI gpaB | gpaI wild type DBS0351267 gpaB-/[act15]:gpbA:YFP gpaB | gpbA abolished aggregation DBS0351214 gpaB-/[act15]:rasG(S17N) gpaB | rasG abolished activation of GTPase activity DBS0236097 gpaB-/[gpaA]:gpaB gpaB abolished aggregation DBS0236099 gpaB-/[gpaB]:gpaB gpaB wild type DBS0236098 gpaB-/[gpaB]:gpaB(Q208L) gpaB aberrant protein localization to plasma membrane DBS0350373 gpaB-/regA- gpaB | regA decreased number of mounds DBS0235986 gpaC- gpaC aberrant activation of adenylate cyclase activity | decreased gene expression | increased protein kinase activity | abolished aggregation JH417 gpaD- gpaD decreased gene expression | aberrant macropinocytosis | decreased spore cell differentiation | aberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased protein kinase activation | abolished protein phosphorylation | decreased cGMP biosynthesis | decreased sporulation DBS0266944 gpaD-/[act15]:gpaB gpaB | gpaD aberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased cGMP biosynthesis DBS0266946 gpaD-/[act15]:gpaB(1-345):gpaD(337-345) gpaB | gpaD aberrant fruiting body morphogenesis | decreased cGMP biosynthesis DBS0266943 gpaD-/[act15]:gpaD gpaD wild type DBS0350608 gpaD-/[act15]:gpaD(Q200L) gpaD development arrests at loose mound stage | decreased chemotaxis to folate | decreased protein kinase activation DBS0350607 gpaD-/[act15]:gpaD(R107E,R108E) gpaD development arrests at slug stage | aberrant slug development DBS0266945 gpaD-/[act15]:gpaE gpaD | gpaE aberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased cGMP biosynthesis DBS0266947 gpaD-/[act15]:gpaE(1-339):gpaD(337-345) gpaD | gpaE aberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased cGMP biosynthesis DBS0351269 gpaD-/[act6]:AEQ gpaD aberrant calcium-mediated signaling DBS0350374 gpaD-/regA- gpaD | regA aberrant aggregation | abolished slug migration | decreased sporulation DBS0350378 gpaD-/regA-/[ecmB]:lacZ gpaD | regA increased prestalk O cell differentiation DBS0236101 gpaE(G196T) gpaE wild type DBS0236103 gpaE(Q198L) gpaE wild type JH257 gpaE- gpaE delayed development of tipped mound | increased chemotaxis to folate | delayed prestalk gene expression | increased vegetative cell size | delayed prespore gene expression | decreased cell migration to prestalk region DBS0266941 gpaE-/[act15]:gpaE gpaE precocious development of tipped mound DBS0266948 gpaE-/[act15]:gpaE(1-339):gpaD(337-345) gpaD | gpaE precocious development of tipped mound DBS0350678 gpaE-/[act15]:gpaE(K10E/K11E) gpaE delayed development of tipped mound | delayed gene expression DBS0350624 gpaE-/erkA- erkA | gpaE wild type | decreased mound size | precocious development LW1 gpaG- gpaG wild type | decreased spore cell differentiation | aberrant GABA signaling pathway DBS0236107 gpaH- gpaH wild type | increased cell death | decreased spore germination | abolished negative chemotaxis | increased growth rate | abolished positive regulation of chemorepellant activity | decreased sporulation DBS0236108 gpaH- gpaH wild type DBS0350972 gpaH-/AX2 gpaH increased growth rate DBS0350975 gpaH-/[ecmO]:lacZ gpaH aberrant cell differentiation DBS0236109 gpaI- gpaI increased number of mounds | aberrant cellular homeostasis | increased establishment of cell polarity | increased cell death | aberrant activation of adenylate cyclase activity | increased chemotaxis to cAMP | precocious aggregation | increased actin filament polymerization | aberrant adaptation of signaling pathway | decreased mound size | decreased oscillatory cAMP signaling | decreased lateral pseudopodium formation | decreased fruiting body size | increased growth rate | aberrant protein localization to plasma membrane | increased cGMP biosynthesis DBS0351544 gpat- gpat aberrant lipid storage | decreased lipid droplet formation | increased sporulation | increased phagocytosis LW5 gpbA- gpbA aberrant taxis | increased resistance to N-Phenylthiourea | abolished aggregation LW6 gpbA- gpbA decreased protein localization to plasma membrane | aberrant cellular homeostasis | aberrant extracellular cAMP signaling pathway | decreased positive regulation of GTPase activity | increased cell death | abolished chemotaxis to folate | aberrant phagocytosis | aberrant chemotaxis | abolished activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased engulfment during phagocytosis | aberrant sorocarp development | decreased chemotaxis to folate | decreased protein kinase activation | decreased chemotaxis to cAMP | abolished actin filament polymerization | increased growth rate | aberrant protein localization | aberrant signal transduction DBS0351277 gpbA- gpbA aberrant cytokinesis DBS0350470 gpbA-/[act15]:GFP:cap cap | gpbA decreased phagocytosis LW14 gpbA-/[act15]:carA carA-1 | carA-2 | gpbA aberrant calcium-mediated signaling | decreased protein kinase activation | abolished aggregation LW17 gpbA-/[act15]:carC carC | gpbA abolished aggregation DBS0351260 gpbA-/[act15]:gpbA(A99T/Y271H/C335M) gpbA abolished activation of adenylate cyclase activity | aberrant fruiting body morphogenesis DBS0351261 gpbA-/[act15]:gpbA(M30V/K85R/S104P/Q163H) gpbA development arrests at mound stage | abolished activation of adenylate cyclase activity | decreased chemotaxis to cAMP DBS0351263 gpbA-/[act15]:gpbA(M48T/I52T/E310G) gpbA wild type | decreased activation of adenylate cyclase activity | decreased gene expression | aberrant slug development DBS0351259 gpbA-/[act15]:gpbA(N147D/H149R/N237S) gpbA development arrests at mound stage | abolished activation of adenylate cyclase activity | abolished chemotaxis to cAMP DBS0351264 gpbA-/[act15]:gpbA(R13G/N74S/S79P/H149R/V178A/V194R/F293L) gpbA decreased activation of adenylate cyclase activity | decreased gene expression | development arrests at tipped mound stage DBS0351262 gpbA-/[act15]:gpbA(S196G/V199D/C211R) gpbA decreased activation of adenylate cyclase activity | aberrant fruiting body morphogenesis DBS0351258 gpbA-/[act15]:gpbA(V88A/F229S/D235V) gpbA abolished activation of adenylate cyclase activity | aberrant fruiting body morphogenesis | decreased chemotaxis to cAMP DBS0351268 gpbA-/[act6]:AEQ gpbA aberrant calcium-mediated signaling HO547 gpbA-/[act6]:FRB:[act15]:RFP:gpbA/[act15]:cnxA:CFP:FKBP/[act15]:limE(1-145):GFP gpbA aberrant cortical actin cytoskeleton organization HO543 gpbA-/[act6]:FRB:[act15]:RFP:gpbA/[act15]:cnxA:YFP:FKBP gpbA abolished chemotaxis to folate DBS0351198 gpbA-/[act6]:yakA gpbA | yakA abolished vegetative growth DBS0350832 gpbA-/[unk]:gpbA(Q208L) gpbA aberrant adaptation of signaling pathway DBS0351278 gpbA-/mhcA- gpbA | mhcA aberrant cytokinesis AK1353 gpi- gpi decreased response to Gram-positive bacterium DBS0350477 gpr89- gpr89 aberrant spore morphology | aberrant mitochondrion morphology | abolished cell migration to prestalk region | decreased gene expression | aberrant slug development | abolished vegetative growth | decreased cell motility | decreased fruiting body size | precocious gene expression | decreased phototaxis | delayed gene expression DBS0350479 gpr89-/[act15]:gpr89:GFP gpr89 wild type DBS0304814 grlA- grlA delayed prestalk gene expression | decreased prestalk gene expression | decreased spore cell differentiation | decreased sporulation | delayed culmination DBS0304815 grlA-/[act15]:grlA:GFP grlA aberrant development of tipped mound DBS0350074 grlB- grlB decreased small molecule binding | aberrant positive regulation of chemorepellant activity | delayed aggregation | aberrant vegetative growth | delayed gene expression DBS0350078 grlB-/grlE- grlB | grlE decreased small molecule binding | delayed aggregation DBS0350227 grlD- grlD aberrant positive regulation of chemorepellant activity | decreased growth rate | aberrant cytokinesis | abolished small molecule binding | aberrant cellular response to extracellular stimulus DBS0236112 grlE- grlE decreased spore cell differentiation | aberrant GABA signaling pathway | decreased sporulation DBS0236113 grlE- grlE delayed aggregation | aberrant gene expression | decreased chemotaxis to cAMP DBS0350075 grlE- grlE decreased spore germination | delayed aggregation DBS0350226 grlH- grlH aberrant positive regulation of chemorepellant activity | aberrant protein level | aberrant vegetative growth | abolished activation of GTPase activity | decreased protein binding | increased growth rate DBS0351147 grlH-/[act15]:grlH grlH wild type DBS0238865 grlJ- grlJ increased migratory slug size | aberrant spore morphology | decreased spore germination | precocious development | decreased fruiting body size | precocious gene expression DBS0350283 grlJ- grlJ aberrant spore morphology | increased resistance to N-Phenylthiourea DBS0238866 grlJ-/[act15]:grlJ:GFP grlJ wild type DBS0350284 grlJ-/[act15]:grlJ:GFP grlJ wild type DBS0238686 grpA- grpA decreased spore germination | abolished protein secretion DBS0238687 grpA-/[act15]:grpA-FLAG grpA wild type ARK200 gskA- gskA abolished stream development | increased gene expression | decreased gene expression | increased protein localization to plasma membrane | decreased chemotaxis to cAMP | decreased sporulation DBS0236114 gskA- gskA aberrant aggregation | decreased protein localization to cell cortex | decreased slug migration | aberrant sorus morphology | aberrant extracellular cAMP signaling pathway | decreased gene expression | abolished protein localization to plasma membrane | abolished protein phosphorylation | decreased chemotaxis to folate | decreased stalk length | abolished chemotaxis to cAMP HM338 gskA- gskA precocious aggregation | decreased prespore cell differentiation | aberrant mitotic spindle elongation | aberrant fruiting body morphogenesis | increased prestalk cell differentiation | decreased sporulation DBS0349930 gskA-/[act15]:GFP:tacA gskA | tacA increased protein localization to nucleus DBS0349881 gskA-/[act15]:gskA(Y214F) gskA abolished stream development DBS0349800 gskA-/[ecmA]:LacZ gskA aberrant prestalk gene expression DBS0349801 gskA-/[ecmB]:LacZ gskA aberrant prestalk gene expression DBS0350260 gskA-/[unk]:pikA(1-492(S7D/S11D/S109D/S113D/S177D/S181D)) gskA | pikA wild type DBS0351102 gskA-/glkA- glkA | gskA aberrant sorocarp development | decreased chemotaxis to cAMP | increased protein kinase activation DBS0350427 gskA-/gskA(K85R):GFP gskA aberrant aggregation DBS0350426 gskA-/gskA:GFP gskA wild type DBS0350988 gst4- gst4 decreased fruiting body size DBS0266891 gtaC- gtaC decreased mound size | aberrant stream morphology | abolished stalk cell differentiation | aberrant prestalk B cell differentiation DBS0350347 gtaC- gtaC abolished gene expression | decreased fruiting body size | abolished aggregation DBS0350348 gtaC-/[act15]:GFP:gtaC gtaC wild type DBS0350357 gtaC-/[act15]:GFP:gtaC(C500,503,522,525S) gtaC aberrant gene expression | abolished aggregation | decreased fruiting body size DBS0350358 gtaC-/[act15]:GFP:gtaC(T376A/S379,380A/C500,503,522,525S) gtaC aberrant protein localization to nucleus DBS0350361 gtaC-/[act15]:gtaC:(468-496):GFP:gtaC gtaC development arrests at mound stage | decreased mound size | precocious development DBS0266892 gtaC-KD gtaC abolished stalk cell differentiation DBS0266893 gtaC-KD/[act15]:GFP:gtaC gtaC wild type DBS0351091 gtaG- gtaG decreased gene expression | development arrests at slug stage | aberrant slug development | decreased prestalk A cell differentiation | decreased sporulation DBS0236120 gxcA- gxcA decreased activation of GTPase activity | decreased actin filament polymerization | delayed development DBS0236121 gxcB- gxcB decreased exocytosis | delayed development | aberrant cytoskeleton organization DBS0350256 gxcC- gxcC delayed development DBS0350257 gxcC-/[act15]:GFP:gxcC gxcC wild type DBS0238825 gxcDD- gxcDD aberrant stream morphology | delayed development LAS105 gxcKK- gxcKK decreased socially cooperative development DBS0350268 gxcT- gxcT aberrant activation of GTPase activity | increased lateral pseudopodium formation | aberrant cytokinesis | decreased growth rate | delayed aggregation | decreased establishment of cell polarity | decreased chemotaxis to cAMP | decreased fruiting body size | aberrant protein localization to plasma membrane DBS0350269 gxcT-/[act15]:GFP:gxcT gxcT wild type DBS0350656 hatA-/[hatB]:hatB hatA | hatB aberrant cellular response to stress DBS0236129 hbx2- hbx2 wild type DBS0236130 hbx2- hbx2 wild type DBS0236131 hbx2-/warA- hbx2 | warA increased basal disc size | development arrests at mound stage | decreased prespore cell differentiation | increased prestalk O cell differentiation DBS0350324 hbx4-/[ecmAO]:lacZ hbx4 increased prespore cell differentiation DBS0350879 hbx9- hbx9 decreased cell-cell adhesion | decreased gene expression | delayed aggregation | decreased growth rate | decreased chemotaxis to cAMP DBS0350880 hbx9-/[ecmA]:lacZ hbx9 increased prestalk A cell differentiation DBS0236153 hcpA- hcpA decreased growth rate DBS0236157 hcpB- hcpB wild type DBS0305109 hdaB- hdaB decreased sporulation | decreased histone deacetylase activity HM1012 helC- helC decreased gene expression | delayed development | aberrant fruiting body morphogenesis HM444 helC- helC decreased gene expression | aberrant fruiting body morphogenesis | delayed development DG1059 helE- helE increased slug migration DBS0236163 helF- helF increased migratory slug size | increased stalk cell differentiation | delayed development | increased post-transciptional gene silencing by RNA DBS0350878 hephA- hephA increased response to cAMP | delayed aggregation | aberrant sorocarp development | decreased cAMP level DBS0350362 hfnA- hfnA increased phototaxis | decreased migratory slug size | increased slug migration DBS0350363 hfnA-/[ecmO]:lacZ hfnA aberrant slug development | aberrant prestalk O cell differentiation DBS0350364 hfnA-/abpC- abpC | hfnA wild type | aberrant prestalk O cell differentiation | decreased phototaxis DBS0351593 hgrA- hgrA | matA aberrant macrocyst formation DBS0351590 hgrA-/KAX3 hgrA aberrant macrocyst formation DBS0351594 hgrB- hgrB | matA aberrant macrocyst formation DBS0351591 hgrB-/KAX3 hgrB aberrant macrocyst formation DBS0238583 hipA- hipA decreased spore germination | aberrant spore morphology | aberrant cortical actin cytoskeleton organization | aberrant spore coat morphology | increased protein localization to plasma membrane DBS0305951 hipA-/epnA- epnA | hipA decreased spore germination | aberrant spore morphology DBS0351165 hspb1- hsbp1-1 | hsbp1-2 decreased exocytosis | decreased protein level | aberrant protein localization to lysosomal membrane DBS0351532 hspc300-/AX2 hspc300 aberrant macropinocytosis | aberrant cytokinesis | decreased cell motility | decreased filopodium formation | abolished protein level DBS0350289 hspc300-/[act15]:myc:hspc300 hspc300 wild type DBS0252818 hssA- hssA wild type DBS0351066 htmA- htmA decreased gene expression | aberrant sorocarp development | increased cell-substrate adhesion | decreased cell motility DBS0349776 htt- htt aberrant cell separation during cytokinesis | decreased growth rate | decreased chemotaxis rate | delayed development | delayed gene expression | decreased myosin II assembly DBS0349788 htt- htt aberrant aggregation | abolished stream development | development arrests at loose mound stage | aberrant cellular response to starvation | aberrant spore morphology | decreased spore germination | abolished cell motility in response to calcium ion | increased number of mound tips | aberrant sorocarp development | aberrant hypotonic response | aberrant actin filament organization | abolished culmination | decreased sporulation | aberrant prespore cell differentiation | abolished calcium-independent cell-cell adhesion | abolished protein level | abolished chemotaxis to cAMP DBS0351281 htt- htt abolished gene expression | aberrant sorus morphology | decreased gene expression | decreased growth rate | aberrant slug development | aberrant sorocarp development | delayed development | decreased cAMP level | aberrant prestalk cell differentiation DBS0349786 htt-/[act15]:htt:GFP htt wild type | aberrant protein level DBS0350438 ibrA- ibrA aberrant substrate adhesion-dependent cell spreading | aberrant contractile vacuole organization | decreased phagocytosis | decreased growth rate | aberrant cytokinesis | aberrant hypotonic response | decreased contractile vacuole discharge DBS0349794 ibrA- ibrA aberrant stalk development DBS0252699 icmA- icmA-1 | icmA-2 abolished sporulation | abolished stream development | aberrant extracellular cAMP signaling pathway | abolished establishment of cell polarity | development arrests at mound stage | abolished vegetative growth | aberrant oscillatory cAMP signaling | aberrant fruiting body morphogenesis | aberrant protein localization to nucleus | delayed gene expression | aberrant protein localization DBS0252702 icmA-/[act15]:TAP:YFP:rasG icmA-1 | icmA-2 | rasG abolished C-terminal protein methylation DBS0252701 icmA-/[act15]:hICMT icmA-1 | icmA-2 wild type DBS0252700 icmA-/[act15]:icmA icmA-1 | icmA-2 wild type DBS0236421 icpA- icpA abolished protein localization to mitotic spindle | aberrant mitosis | aberrant cytokinesis | abolished protein localization to cleavage furrow | abolished protein localization to mitotic spindle midzone | aberrant protein localization DBS0238521 icpA-/[act15]:GFP:icpA(1-1013) icpA aberrant protein localization to mitotic spindle BS153 ifkA- ifkA increased mound size | precocious aggregation | precocious gene expression | decreased protein secretion BS161 ifkA-/ifkB- ifkA | ifkB increased mound size | increased number of mound tips | increased cell-cell adhesion | increased cell-substrate adhesion | aberrant fruiting body morphogenesis BS160 ifkB- ifkB increased prestalk gene expression DBS0236425 ino1- ino1 increased number of mound tips | decreased phagocytosis | abolished vegetative growth | increased 2,3-bisphosphoglycerate level | decreased myo-inositol level DBS0350801 ino1- ino1 aberrant cellular metabolic process | increased number of autophagosomes | decreased cell-substrate adhesion | aberrant phosphatidylinositol metabolism | aberrant cytokinesis | abolished vegetative growth | aberrant fruiting body morphogenesis | decreased myo-inositol level DBS0266326 iplA- iplA abolished cellulose biosynthesis | abolished autophagosome organization | abolished autophagic cell death | aberrant autophagic cell death HM1038 iplA- iplA aberrant cell motility | precocious aggregation | delayed aggregation | aberrant chemotaxis | aberrant calcium-mediated signaling | increased bleb assembly | increased chemotaxis to arachidonic acid | abolished positive regulation of chemorepellant activity DBS0351539 iplA-/AX2 iplA abolished response to DIF-1 | abolished response to cAMP | aberrant GABA signaling pathway DBS0350439 iplA-/[act15]:GFP:iplA iplA wild type DBS0252878 iptA- iptA decreased spore germination | aberrant sporulation DBS0350400 iqgC- iqgC decreased myosin II assembly DBS0351225 iqgC- iqgC aberrant cytokinesis | increased macropinocytosis | increased phagocytosis DBS0351435 ireA- ireA increased number of autophagosomes | decreased protein level | aberrant vacuole organization | aberrant gene expression | aberrant cellular response to stress | aberrant endoplasmic reticulum organization | aberrant protein localization DBS0351436 ireA-/[act15]:ireA(K603N):GFP ireA decreased protein level | aberrant endoplasmic reticulum organization | aberrant cellular response to stress DBS0351437 ireA-/[act15]:ireA(N927A):GFP ireA decreased protein level | aberrant endoplasmic reticulum organization | aberrant cellular response to stress DBS0236031 kctd9- kctd9 wild type DBS0350057 keaA- keaA aberrant extracellular cAMP signaling pathway | decreased gene expression | delayed aggregation | decreased growth rate | decreased cAMP level DBS0350472 kif1- kif1 aberrant transport DBS0350959 kif10-/[act15]:dhcA(1384-4725) dhcA | kif10 wild type DBS0350038 kif11- kif11 wild type DBS0236489 kif12- kif12 aberrant protein localization to mitotic spindle | aberrant cell separation during cytokinesis | aberrant cytokinesis | aberrant myosin II filament organization | increased bleb assembly DBS0236490 kif12-/[act15]:FLAG:kif12 kif12 wild type DBS0302534 kif13- kif13 precocious mitotic spindle elongation | aberrant mitotic spindle organization DBS0350039 kif4- kif4 decreased growth rate DBS0350042 kif4-/[act15]:dhcA(1384-4725) dhcA | kif4 aberrant mitotic spindle organization DBS0350021 kif5- kif5 wild type DBS0350022 kif5-/[act15]:FLAG:kif5 kif5 aberrant cytokinesis | aberrant cell morphology DBS0350023 kif5-/[act15]:FLAG:kif5(342-990) kif5 aberrant cell morphology DBS0350024 kif5-/[act15]:GFP:kif5(805-990) kif5 aberrant cytokinesis DBS0236494 kif7- kif7 decreased cell migration to prestalk region DBS0350040 kif8- kif8 aberrant microtubule cytoskeleton organization DBS0350947 kif8-/[act15]:dhcA(1384-4725) dhcA | kif8 wild type DBS0349964 kif9- kif9 aberrant mitotic spindle organization | aberrant mitosis | decreased growth rate | aberrant protein localization to nuclear envelope | aberrant centrosome localization | aberrant centromere complex assembly | aberrant centrosome organization DBS0236491 kil1- kil1 abolished defense response to Gram-negative bacterium | increased defense response to fungus DBS0351457 kil1-/lrrkA- drkD | kil1 aberrant defense response to bacterium DBS0350043 kil2- kil2 aberrant response to cation stress | aberrant defense response to bacterium | decreased protein processing in phagocytic vesicle | abolished defense response to Gram-negative bacterium | increased defense response to fungus DBS0350874 kil2- kil2 aberrant defense response to bacterium | decreased growth rate DBS0350044 kil2-/[act15]:kil1 kil1 | kil2 abolished defense response to bacterium DBS0351458 kil2-/lrrkA- drkD | kil2 aberrant defense response to bacterium DBS0350875 kil2-/vps13F- kil2 | vps13F aberrant defense response to bacterium | decreased growth rate DBS0351502 knkA- knkA decreased spore germination | aberrant spore morphology | decreased number of autophagosomes | decreased prespore gene expression | aberrant fruiting body morphogenesis | aberrant phototaxis | decreased sporulation DBS0236492 krsA- krsA decreased chemotaxis to cAMP DBS0238720 krsA- krsA abolished stream development | precocious culmination | abolished activation of adenylate cyclase activity | decreased vegetative cell size | decreased mound size | aberrant hyperosmotic response | precocious gene expression | decreased cAMP level DBS0236493 krsA-/[act15]:GFP:krsA krsA wild type DBS0238721 krsA-/[act15]:GFP:krsA krsA wild type DBS0238722 krsA-/[act15]:GFP:krsA(K49R) krsA aberrant stream morphology DBS0238723 krsA-/[act15]:GFP:krsA(T173A) krsA abolished stream development DBS0238725 krsA-/[act15]:GFP:krsA(deltaC) krsA aberrant stream morphology DBS0238724 krsA-/[act15]:GFP:krsA(deltaKinase) krsA abolished stream development DBS0238726 krsA-/[act15]:GFP:krsA(deltaNS) krsA abolished stream development DBS0350598 krsB- krsB aberrant stream morphology | decreased cell motility | increased cell-substrate adhesion | delayed development | decreased chemotaxis to cAMP DBS0350599 krsB-/[tet]:krsB(T176A):GFP krsB aberrant stream morphology DBS0350600 krsB-/krsA- krsA | krsB aberrant stream morphology | delayed development DBS0236495 ku80- ku80 decreased resistance to bleomycin | decreased double-strand break repair via nonhomologous end joining DBS0350536 ku80-/dclre1- dclre1 | ku80 wild type DBS0350537 ku80-/myc:ku80(1-782) ku80 decreased double-strand break repair via nonhomologous end joining DBS0236498 lagD- tgrD1 aberrant aggregation | abolished stream development | aberrant extracellular cAMP signaling pathway DBS0236499 limB- limB decreased cell-substrate adhesion | abolished cell migration to prestalk region | development arrests at mound stage | delayed prestalk gene expression | aberrant cell-cell adhesion | decreased prestalk gene expression | decreased chemotaxis rate | aberrant actin filament organization | decreased establishment of cell polarity DBS0236502 limB-/[act15]:paxB:GFP limB | paxB development arrests at mound stage DBS0236500 limB-/[cotC]:limB limB development arrests at mound stage DBS0236501 limB-/[ecmAO]:limB limB wild type DBS0236729 limB-/paxB- limB | paxB development arrests at mound stage DBS0350563 limC- limC delayed aggregation | decreased growth rate | aberrant cytokinesis | aberrant response to osmotic stress DBS0350564 limD1- limD1 increased lateral pseudopodium formation | delayed aggregation | decreased growth rate | aberrant cytokinesis | aberrant response to osmotic stress | decreased chemotaxis to cAMP | decreased establishment of cell polarity | aberrant actin filament organization DBS0350565 limD1-/limC- limC | limD1 delayed aggregation | aberrant cytokinesis | abolished vegetative growth | aberrant response to osmotic stress | decreased chemotaxis to cAMP | aberrant actin filament organization | decreased establishment of cell polarity DBS0236503 limE- limE aberrant cytokinesis DBS0236506 limF- limF decreased phagocytosis DBS0236511 lipA- lipA wild type DBS0236512 lipA- lipA wild type DG1006 lipA- lipA abolished culmination DG1056 lipB- captC aberrant fruiting body morphogenesis DBS0236515 lis1(D327H) lis1 aberrant microtubule cytoskeleton organization | increased actin phosphorylation | aberrant Golgi localization DBS0349950 lmbd2B- lmbd2B aberrant chemotaxis | delayed development | aberrant cell morphology | increased pseudopodium formation DBS0349982 lmnB- lmnB aberrant chromatin assembly | aberrant centrosome localization DBS0350354 lmpA- lmpA decreased lysosomal protein degradation | decreased pinocytosis | decreased protein level | decreased phagocytosis | decreased growth rate | decreased cell motility | decreased protein processing in phagocytic vesicle | aberrant phagosome maturation | decreased fruiting body size | decreased defense response to Gram-positive bacterium | decreased sporulation DBS0351481 lmpB- lmpB decreased phagocytosis DBS0351482 lmpC- lmpC decreased protein localization to cell surface | increased protein localization to cell surface DBS0350452 lpten- lpten aberrant cell motility | decreased lateral pseudopodium retraction DBS0350453 lpten-/[act15]:lpten:RFP lpten wild type DBS0236516 lrrA- lrrA increased mound size | decreased spore germination | decreased cell-substrate adhesion | abolished establishment of cell polarity | decreased gene expression | development arrests at mound stage | increased actin filament polymerization | abolished positive chemotaxis | abolished aggregation | delayed gene expression DBS0350407 lrrB- lrrB aberrant thermotaxis | delayed slug development | aberrant gene expression | aberrant sorocarp development | decreased prestalk gene expression | aberrant phototaxis | aberrant late culminant morphology DBS0350478 lrrB-/[ecmB]:lacZ lrrB aberrant prestalk B cell differentiation DBS0350476 lrrB-/[ecmO]:lacZ lrrB aberrant prestalk O cell differentiation DBS0351456 lrrkA- drkD aberrant defense response to bacterium | decreased protein processing in phagocytic vesicle | abolished vegetative growth DBS0236517 lst8- lst8 aberrant activation of adenylate cyclase activity | decreased actin filament polymerization | decreased chemotaxis rate | abolished aggregation | decreased myosin II assembly | abolished positive regulation of chemorepellant activity DBS0350106 lst8- lst8 increased phagocytosis DBS0350114 lst8-/[act15]:GFP:rheb(Q64L) lst8 | rheb increased phagocytosis DBS0309063 lvsA- lvsA increased bleb assembly AD60 lvsA- lvsA abolished cytokinesis | decreased pinocytosis | aberrant contractile vacuole organization | decreased phagocytosis | aberrant hypotonic response | increased cell-substrate adhesion AD63 lvsA- lvsA abolished cytokinesis | abolished contractile vacuole dissociation from plasma membrane | aberrant calcium-mediated signaling DBS0237207 lvsA-/[act6]:GFP:lvsA(1828- 3619) lvsA abolished cytokinesis DBS0236521 lvsB- lvsB increased secretion of lysosomal enzymes | increased lysosome size | increased exocytosis | increased pinocytosis | aberrant protein localization to post-lysosomal vacuole | aberrant phagosome maturation | increased endosome size | aberrant post-lysosomal vacuole exocytosis | increased endosomal vesicle fusion | aberrant lysosome organization DBS0350567 lvsB-/[act15]:FLAG:Rab14(N121I) lvsB | rab14 wild type DBS0238218 lvsB-[act6]:TAP:GFP:lvsB lvsB wild type DBS0236522 lvsC- lvsC wild type DBS0236523 lvsD- lvsD wild type DBS0236524 lvsE- lvsE wild type DBS0236525 lvsF- lvsF wild type DBS0351162 lyC2- lyC2 decreased growth rate DBS0349933 macA- macA aberrant macrocyst formation | decreased sexual fusion DBS0236536 malA- malA wild type DBS0351251 matA- matA abolished mating type determination HM1524 matA- matA abolished mating type determination DBS0350211 mef2A- mef2A decreased growth rate | aberrant sorocarp development | aberrant stream morphology | decreased sporulation DBS0350212 mef2A- mef2A decreased growth rate | aberrant stream morphology | aberrant sorocarp development | aberrant gene expression | decreased sporulation DBS0350213 mef2A-/[ecmA]:lacZ mef2A aberrant prestalk A cell differentiation DBS0350214 mef2A-/[ecmB]:lacZ mef2A aberrant prestalk B cell differentiation DBS0350215 mef2A-/[pspA]:lacZ mef2A decreased prespore cell differentiation DBS0236543 mekA- mekA decreased mound size | precocious development | abolished chemotaxis to cAMP DBS0350030 mekA-/[act15]:Myc:erkA erkA | mekA abolished protein localization to cell cortex DBS0350036 mekA-/[act15]:mekA(299-360) mekA decreased mound size DBS0350035 mekA-/[act15]:mekA(K321A) mekA decreased mound size DBS0350032 mekA-/[act15]:mekA(S444A/T448A) mekA decreased mound size DBS0350031 mekA-/[act15]:mekA(S444E/T448E) mekA development arrests at mound stage DBS0238098 mekA-/ppp4C- mekA | ppp4c decreased mound size DBS0238109 mekA-/ppp4C-/[act15]:FLAG:pppC ppp4c decreased mound size | precocious development DBS0236542 mekA-/smkA- mekA | smkA decreased mound size DBS0236544 mfeA- mfeA aberrant cellular metabolic process | decreased protein level | aberrant extracellular cAMP signaling pathway | development arrests at mound stage DBS0351543 mfsd8- mfsd8 increased protein secretion DBS0266843 mgp1- mgp1 increased phototaxis | abolished stream development | increased filopodium formation | aberrant contractile vacuole organization | decreased cell motility | decreased fruiting body size | decreased stalk width | decreased stalk length DBS0266846 mgp1-/mgp2- mgp1 | mgp2 increased filopodium formation | aberrant contractile vacuole organization | aberrant culmination | decreased cell motility | decreased phototaxis | decreased stalk length DBS0266844 mgp2- mgp2 increased migratory slug size | increased mound size HS1 mhcA- mhcA development arrests at mound stage | aberrant cytokinesis | decreased growth rate | increased actin filament polymerization | aberrant hypotonic response | aberrant regulation of GTPase activity | abolished bleb assembly | aberrant regulation of protein kinase activity | aberrant cellular response to stress HS2205 mhcA- mhcA abolished cell motility | decreased cell motility HS2207 mhcA- mhcA abolished cytokinesis | development arrests at mound stage DBS0350064 mhcA- mhcA decreased cell motility | decreased establishment of cell polarity HS2206 mhcA- mhcA aberrant cellular response to fluid shear stress | abolished bleb assembly HK321 mhcA- mhcA aberrant cortical actin cytoskeleton organization | aberrant chemotaxis to folate | aberrant cell morphology HK323 mhcA- mhcA decreased cell motility | aberrant stream morphology DBS0266674 mhcA-/[act15]:GFP:abpC(9-148) abpC | mhcA decreased uropod retraction | decreased pseudopodium retraction DBS0237564 mhcA-/[act15]:GFP:ctxA/[RNAi]enlA ctxA | enlA | mhcA aberrant mitotic actomyosin contractile ring contraction DBS0266675 mhcA-/[act15]:GFP:mhcA(E476K) mhcA decreased pseudopodium retraction DBS0350489 mhcA-/[act15]:GFP:mhcA/[RNAi]rmd1 mhcA | rmd1 abolished protein localization to cleavage furrow DBS0236548 mhcA-/[act15]:GFP:pats1(2087-2351) mhcA | pats1 aberrant cytokinesis DBS0350291 mhcA-/[act15]:gppA:GFP gppA | mhcA aberrant contractile vacuole morphology | decreased contractile vacuole discharge DBS0236549 mhcA-/[act15]:limE(1-145):GFP limE | mhcA increased actin filament polymerization DBS0350808 mhcA-/[act15]:mhcA(1-933:1455-2116] mhcA wild type | aberrant cytokinesis | aberrant fruiting body morphogenesis DBS0238158 mhcA-/[act15]:mhcA(81-2116) mhcA decreased growth rate | development arrests at tipped mound stage CW0401 mhcA-/[act15]:mhcA(T1823A/T1833A/T2029A) mhcA increased myosin II assembly | decreased growth rate | aberrant chemotaxis DBS0236550 mhcA-/[act15]:mhcA(T1823A/T1833A/T2029A) mhcA decreased filopodium formation DBS0236551 mhcA-/[act15]:mhcA(T1823D/T1833D/T2029D) mhcA increased filopodium formation DBS0238399 mhcA-/[act15]:rapA(G12V) mhcA | rapA increased establishment of cell polarity | increased actin filament polymerization | aberrant myosin II filament organization DBS0236552 mhcA-/[mhcA]:mhcA(1-1224) mhcA aberrant cytokinesis | development arrests at mound stage DBS0350948 mhcA-/[mhcA]:mhcA(1-1224)/[act15]:mhcA(E683K) mhcA aberrant catalytic activity DBS0350949 mhcA-/[mhcA]:mhcA(1-1224)/[act15]:mhcA(R686C) mhcA aberrant catalytic activity DBS0238157 mhcA-/[mhcA]:mhcA(1-1224)/[act15]:mhcA(R689H) mhcA decreased actin filament sliding DBS0236547 mhcA-/[unk]:GFP:icpA icpA | mhcA decreased protein localization to cleavage furrow DBS0350668 mhcA-/forA- forA | mhcA abolished cell motility | decreased cell motility DBS0351411 mhcA-/piaA- mhcA | piaA aberrant cytokinesis CW0371 mhkA- mhkA increased myosin II assembly | aberrant chemotaxis | decreased cell motility | aberrant protein localization to pseudopodium DBS0236557 mhkA-/[act15]:mhkA mhkA decreased growth rate | development arrests at mound stage | aberrant cytokinesis | decreased myosin II assembly CW0431 mhkA-/mhkB-/mhkC- mhkA | mhkB | mhkC increased myosin II assembly | decreased growth rate | aberrant cytokinesis | aberrant chemotaxis | decreased cell motility DBS0236556 mhkA-/mhkC- mhkA | mhkC increased myosin II assembly | decreased growth rate | aberrant cytokinesis CW0394 mhkA/mhkB mhkA | mhkB increased myosin II assembly | decreased growth rate | aberrant cytokinesis CW0166 mhkB- mhkB increased myosin II assembly | decreased cell motility CW0403 mhkC- mhkC increased myosin II assembly | aberrant cytokinesis | aberrant chemotaxis DG1069 mhkC- mhkC aberrant fruiting body morphogenesis CW0435 mhkD- mhkD increased myosin II assembly | decreased cell motility DBS0236559 midA- midA decreased pinocytosis | aberrant cellular homeostasis | aberrant spore morphology | decreased glycogen level | increased ammonia level | decreased thermotaxis | increased autophagy | decreased mitochondrial fission | decreased growth rate | decreased phagocytosis | decreased vegetative cell size | increased slug migration | increased glutamate level | decreased phototaxis DBS0350123 midA-/[act15]:GFP:atg18 atg18 | midA increased number of autophagosomes DBS0350136 midA-/[act15]:GFP:tkt midA | tkt-1 | tkt-2 increased autophagy DBS0351180 midA/[act15]:midA(E200A) midA aberrant cellular homeostasis | decreased growth rate | decreased phototaxis DBS0351182 midA/[act15]:midA(G170V/G172V) midA aberrant cellular homeostasis | decreased growth rate | decreased phototaxis DBS0351181 midA/[act15]:midA(N205A) midA aberrant cellular homeostasis | decreased growth rate | decreased phototaxis DG1020 migA- migA abolished slug migration | decreased mound size | aberrant fruiting body morphogenesis | decreased fruiting body size DBS0350958 migA- migA decreased gene expression | aberrant chemotaxis to cAMP DBS0350025 mip1- mip1-1 | mip1-2 increased mound size | decreased chemotaxis to cAMP DBS0350027 mip1-/[act15]:mekA:FLAG mekA | mip1-1 | mip1-2 aberrant protein localization to cytoplasm DBS0266620 mipp1- mipp1 aberrant inositol phosphate metabolic process | increased response to lithium DBS0309109 mipp1-/dpoA- dpoA | mipp1 aberrant inositol phosphate metabolic process | increased response to lithium DBS0236560 mkcA- mkcA decreased prestalk gene expression DBS0236561 mkcA-/tagB- mkcA | tagB decreased sporulation DBS0236562 mkcA-/tagC- mkcA | tagC decreased sporulation DG1101 mkcB- mkcB decreased fruiting body size DBS0236564 mkkA- mkkA precocious culmination | decreased sorus size | increased stalk length DG1121 mkpA- mkpA abolished aggregation DBS0236566 mlcE- mlcE aberrant cytokinesis | decreased growth rate | delayed aggregation | aberrant taxis | aberrant sorocarp development | decreased cell motility | aberrant gene expression DBS0238058 mlcE-/[act15]:myc:mlcE mlcE wild type DBS0236567 mlcR- mlcR aberrant cytokinesis | development arrests at mound stage | aberrant myosin II filament organization DBS0351550 mlcR-/[ecmAO]:GFP mlcR aberrant development of tipped mound HS183 mlkA- mlkA aberrant cytokinesis DBS0349919 mlkA-/[act15]:GFP-mhcA mlkA aberrant stalk morphogenesis DG1033 modA- modA decreased response to Gram-negative bacterium | abolished catalytic activity | aberrant fruiting body morphogenesis DBS0266903 mpl1- mpl1 abolished stream development | decreased cell motility | decreased chemotaxis to cAMP | abolished aggregation DBS0266904 mpl1-/[act15]:flag:mpl1 mpl1 wild type DBS0349986 mrfA- mrfA aberrant slug migration | delayed development DBS0350391 mrfA-/[act15]:myc:mrfA(K772A):FLAG mrfA aberrant protein modification DBS0350390 mrfA-/[act15]:myc:mrfA(S767A):FLAG mrfA aberrant protein modification | delayed development DBS0350389 mrfA-/[act15]:myc:mrfA:FLAG mrfA wild type DBS0349987 mrfA-/[emcA]:lacZ mrfA decreased prestalk A cell differentiation DBS0349988 mrfA-/dimB-/[emcA]:lacZ dimB | mrfA decreased prestalk A cell differentiation DBS0350960 mroh1- mroh1 aberrant exocytosis | decreased lysosome size DBS0236569 mrps4- mrps4 delayed aggregation | aberrant fruiting body morphogenesis DBS0304881 mrps4- mrps4 delayed aggregation DBS0351541 mscS-/mclN-/pkd2- mcln | mscS | pkd2 aberrant calcium-mediated signaling DBS0304882 mtDNA- DidioMp05 | DidioMp21 | DidioMp26 | DidioMp27 | DidioMp30 | DidioMp35 | DidioMp36 | ai2a | ai2b | ai3 | ai4 | atp1 | atp4 | atp6 | atp8 | atp9 | cox1/2 | cox3 | cytB | mrpl11 | mrpl14 | mrpl16 | mrpl2 | mrpl6 | mrps12 | mrps13 | mrps14 | mrps19 | mrps2 | mrps4 | mrps7 | mrps8 | nad1 | nad11 | nad2 | nad3 | nad4 | nad4L | nad5 | nad6 | nad7 | nad9 | rnlA abolished vegetative growth | abolished aggregation DBS0350868 mtpn- mtpn decreased actin filament polymerization | decreased growth rate | decreased cell motility | aberrant stream morphology | decreased macropinocytosis HM1464 mus81- mus81 wild type DBS0350866 mvpA- mvpA aberrant cell morphology DBS0351489 mvpA-/mvpB- mvpA | mvpB decreased growth rate | aberrant cellular component organization DBS0236570 mybB- mybB decreased gene expression | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | abolished aggregation DBS0236571 mybB- mybB abolished aggregation HM388 mybC- mybC decreased gene expression | development arrests at slug stage | decreased prespore gene expression | abolished culmination DBS0236572 mybE- mybE increased migratory slug size | increased gene expression | abolished outer basal disc formation DBS0349993 mybE-/[btg]:lacZ btg | mybE increased gene expression DBS0237709 mybE-/[mrrA]:lacZ mrrA | mybE aberrant prestalk cell differentiation DBS0236573 mybE-/mybE:GFP mybE wild type | aberrant prestalk cell differentiation HDT1 myoA- myoA aberrant aggregation | decreased lateral pseudopodium retraction | delayed aggregation | decreased cell motility | decreased chemotaxis rate | aberrant pseudopodium formation | decreased chemotaxis to cAMP HDT2 myoA- myoA increased secretion of lysosomal enzymes | delayed aggregation HDT5 myoA-/myoB- myoA | myoB decreased pinocytosis | increased secretion of lysosomal enzymes | increased filopodium formation | aberrant aggregation | aberrant endosomal transport | decreased defense response to Gram-negative bacterium | aberrant cortical actin cytoskeleton organization | increased lateral pseudopodium formation | decreased growth rate | delayed aggregation | decreased cell motility | decreased fruiting body size | aberrant actin filament organization | decreased chemotaxis to cAMP | aberrant cytoskeleton organization DBS0350990 myoA-/myoB-/[act15]:myoB myoA | myoB delayed aggregation DBS0350991 myoA-/myoB-/[act15]:myoB(1-1057) myoA | myoB decreased pinocytosis | decreased growth rate | aberrant actin filament organization DBS0350992 myoA-/myoB-/[act15]:myoB(S332) myoA | myoB decreased pinocytosis | decreased growth rate | aberrant actin filament organization DBS0351038 myoA-/myoF- myoA | myoF decreased lateral pseudopodium retraction | decreased cell motility | decreased chemotaxis to cAMP | aberrant cell morphology | abolished aggregation DBS0236579 myoB- myoB increased secretion of lysosomal enzymes | aberrant aggregation | decreased lateral pseudopodium retraction | decreased cell motility | decreased chemotaxis to cAMP DBS0236580 myoB- myoB increased lateral pseudopodium formation | decreased phagocytosis | delayed aggregation | decreased cell motility DBS0349853 myoB- myoB decreased phagolysosome size | delayed phagosome reneutralization | aberrant phagosome maturation DBS0236583 myoB-/[AS]myoD myoB | myoD decreased pinocytosis | aberrant aggregation | decreased growth rate | decreased phagocytosis | decreased mound size | decreased cell motility DBS0236584 myoB-/[AS]myoD/[KD]myoC myoB | myoC | myoD decreased pinocytosis | aberrant aggregation | decreased pinosome size | decreased growth rate | decreased phagocytosis | decreased mound size | decreased cell motility | increased number of pinosomes DBS0351378 myoB-/[act15]:GFP:myoB(1-720) myoB abolished protein localization to plasma membrane DBS0351379 myoB-/[act15]:GFP:myoB(1-800,813-1111) myoB abolished protein localization to actin wave | abolished protein localization to plasma membrane DBS0351380 myoB-/[act15]:GFP:myoB(713-1111) myoB abolished protein localization to leading edge DBS0351367 myoB-/[act15]:myoB(S332A) myoB abolished protein phosphorylation HDT6 myoB-/myoC- myoB | myoC increased secretion of lysosomal enzymes | decreased pinocytosis | increased filopodium formation | decreased growth rate | decreased cell motility | decreased fruiting body size | aberrant actin filament organization | aberrant cytoskeleton organization DBS0236585 myoC- myoC decreased phagocytosis HDT4 myoC- myoC decreased pinocytosis | decreased phagocytosis DBS0236587 myoD- myoD wild type DBS0351031 myoD-/myoE- myoD | myoE decreased fruiting body size DBS0351034 myoD-/myoE-/myoF- myoD | myoE | myoF decreased actin filament polymerization | aberrant engulfment during phagocytosis | decreased chemotaxis to cAMP | decreased fruiting body size DBS0351033 myoD-/myoF- myoD | myoF decreased fruiting body size DBS0351032 myoE-/myoF- myoE | myoF decreased fruiting body size HDT8 myoF- myoF aberrant aggregation | wild type | increased lateral pseudopodium formation | decreased cell motility | decreased chemotaxis to cAMP | aberrant cell morphology DBS0350251 myoG- myoG decreased protein localization to plasma membrane | decreased actin filament polymerization | abolished establishment of cell polarity | aberrant chemotaxis to cAMP | abolished aggregation DBS0236589 myoI- myoI decreased spore germination DBS0236592 myoI- myoI decreased cell-substrate adhesion | aberrant cytokinesis | decreased phagocytosis | aberrant cell morphology HDT15 myoI- myoI decreased phagocytosis HDT17 myoI- myoI decreased cell-cell adhesion | decreased protein level | decreased cell-substrate adhesion | decreased phagocytosis | decreased filopodium formation DBS0266889 myoI-/[act15]:GFP:myoI myoI wild type DBS0351400 myoI-/[act15]:GFP:myoI(1-1020) myoI abolished protein localization to pseudopodium | decreased filopodium formation DBS0351398 myoI-/[act15]:GFP:myoI(2057-2357) myoI increased filopodium formation DBS0266890 myoI-/[act15]:GFP:myoI(809-1154) myoI decreased phagocytosis DBS0351399 myoI-/[act15]:GFP:myoI(K23333A,K2336A) myoI increased filopodium formation DBS0237617 myoI-/[act15]:gbpD gbpD | myoI increased cell-substrate adhesion | aberrant cell morphology | increased pseudopodium formation HTD7 myoJ- myoJ wild type DBS0350931 myoJ- myoJ decreased hypotonic response | aberrant contractile vacuole discharge | aberrant contractile vacuole localization DBS0349844 myoK- myoK aberrant cortical actin cytoskeleton organization | delayed aggregation | decreased phagocytosis | aberrant engulfment during phagocytosis | aberrant phagosome maturation | decreased chemotaxis rate | aberrant cell morphology | delayed phagosome acidification DBS0349846 myoK-/[act15]:YFP:myoK(1-121:262-858) myoK decreased phagocytosis DBS0349850 myoK-/[act15]:myoK myoK increased phagocytosis DBS0349854 myoK-/[act15]:pakB(1-337:563-852) myoK | pakB wild type DBS0236595 myoM- myoM wild type DBS0351046 nad2- nad2 decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant fruiting body morphogenesis | aberrant phototaxis DBS0351048 nad5- nad5 decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis AK1372 nagB1- nagB1 decreased response to Gram-positive bacterium DBS0236596 napA- napA aberrant cellular response to extracellular stimulus SB12 napA- napA decreased cell-cell adhesion | decreased cell-substrate adhesion | decreased actin filament polymerization | decreased cell motility | decreased vegetative cell size | decreased establishment of cell polarity | decreased phototaxis DBS0351534 napA-/AX2 napA decreased protein level | increased membrane ruffling | aberrant cytokinesis | increased vegetative cell size | decreased cell motility SB14 napA-/pirA- napA | pirA decreased actin filament polymerization HC476 ncsA- ncsA increased cAMP level | precocious gene expression | precocious development HC477 ncsA- ncsA increased cAMP level | precocious gene expression | precocious development DBS0350297 ncstn- ncstn aberrant culmination | abolished catalytic activity | decreased prespore cell differentiation DBS0350307 ncstn- ncstn wild type | aberrant sorocarp development | decreased macropinocytosis DBS0350301 ncstn-/psenA- ncstn | psenA aberrant culmination | decreased prespore cell differentiation DBS0349947 ndm- ndm aberrant chemotaxis | increased pinocytosis | decreased fruiting body size | aberrant pseudopodium formation DBS0349895 ndrA- ndrA decreased engulfment during phagocytosis DBS0349896 ndrA-/[unk]:GFP:ndrA ndrA wild type DBS0350446 ndrC- ndrC increased positive regulation of GTPase activity | increased number of centrosomes | aberrant cell separation during cytokinesis DBS0350121 ndufaf5- ndufaf5 aberrant spore morphology | decreased growth rate | delayed development | aberrant phototaxis | decreased fruiting body size | decreased sporulation DBS0350125 ndufaf5--/[act15]:ndufaf5(G86V):GFP:TAP ndufaf5 decreased growth rate DBS0350126 ndufaf5--/[act15]:ndufaf5(L165F):GFP:TAP ndufaf5 decreased growth rate DBS0350127 ndufaf5--/[act15]:ndufaf5(L235P):GFP:TAP ndufaf5 decreased growth rate DBS0350124 ndufaf5--/[act15]:ndufaf5:GFP:TAP ndufaf5 wild type DBS0350122 ndufaf5-/[act15]:GFP:atg18 atg18 | ndufaf5 increased number of autophagosomes DBS0350134 ndufaf5-/[act15]:GFP:tkt ndufaf5 | tkt-1 | tkt-2 increased autophagy DBS0350137 ndufaf5-/[act15]:[AS]snfA ndufaf5 | snfA aberrant phototaxis DBS0304633 nfaA- nfaA aberrant extracellular cAMP signaling pathway | aberrant activation of GTPase activity | increased actin filament polymerization | delayed aggregation | decreased cell motility | aberrant regulation of GTPase activity | aberrant regulation of protein kinase activity | aberrant protein localization to plasma membrane | decreased chemotaxis to cAMP | increased pseudopodium formation DBS0304634 nfaA-/rasG- nfaA | rasG decreased establishment of cell polarity DBS0351061 ngap- ngap aberrant regulation of fruiting body formation | aberrant extracellular cAMP signaling pathway | aberrant adaptation of signaling pathway | increased actin filament polymerization | aberrant chemotaxis to cAMP | aberrant regulation of protein kinase activity | decreased establishment of cell polarity | increased activation of GTPase activity DBS0236604 nhe1- nhe1 abolished cell motility in response to calcium ion | decreased intracellular pH | abolished establishment of cell polarity | decreased actin filament polymerization | decreased chemotaxis rate | delayed development | aberrant actin filament organization | decreased establishment of cell polarity | abolished chemotaxis to cAMP DBS0350003 nhe1-/[act15]:GFP:aip1 aip1 | nhe1 decreased establishment of cell polarity | decreased chemotaxis to cAMP DBS0350006 nhe1-/[act15]:GFP:aip1(E125A, E167A, F181A, F193A) aip1 | nhe1 abolished aggregation | abolished chemotaxis to cAMP DBS0350001 nhe1-/[act15]:aip1(168-597) aip1 | nhe1 delayed development DBS0350002 nhe1-/[act15]:aip1(383-597):FLAG aip1 | nhe1 decreased actin filament polymerization | abolished establishment of cell polarity | abolished chemotaxis to cAMP DBS0349841 nhe1-/[act15]:mhcA:GFP mhcA | nhe1 abolished protein localization to trailing edge DBS0236605 nhe1-/[act15]:nhe1:HA nhe1 wild type DBS0350508 nlp- nlp wild type DBS0350509 nlp-/slp- nlp | slp decreased actin filament polymerization | aberrant organelle organization | abolished protein localization to cytoplasmic vesicle | decreased chemotaxis to cAMP DBS0351466 nola4(I23T) nola4 decreased resistance to bleomycin | decreased growth rate | increased growth rate | aberrant response to oxidative stress DBS0351467 nola4(T33M) nola4 decreased resistance to bleomycin | decreased gene expression | decreased growth rate | increased growth rate | aberrant response to oxidative stress DBS0236606 nosA null (15-S-12) nosA development arrests at mound stage DBS0236607 nosA null (2E4) nosA development arrests at mound stage DBS0235950 nosA- nosA development arrests at mound stage | aberrant protein modification DBS0236941 nosA-/sonA- nosA | sonA wild type DBS0236608 noxA- noxA abolished sporulation | aberrant sorocarp development DBS0236611 noxA-/[act15]:noxA:myc2 noxA aberrant fruiting body morphogenesis DBS0236610 noxA-/noxB noxA | noxB abolished sporulation | aberrant sorocarp development | decreased superoxide generation DBS0350768 noxA-/noxB-/noxC- noxA | noxB | noxC aberrant defense response to bacterium DBS0236612 noxB- noxB abolished sporulation | aberrant sorocarp development | decreased superoxide generation DBS0236613 noxC- noxC abolished sporulation | aberrant sorocarp development DBS0238849 npcA- npcA wild type HSB60 nramp1- nramp1 decreased defense response to Gram-negative bacterium | decreased defense response to Gram-positive bacterium | abolished iron ion transport DBS0236696 nramp1-/[act15]:nramp1:GFP nramp1 increased defense response to Gram-negative bacterium DBS0236697 nramp1-/[act15]:nramp1:GFP nramp1 increased defense response to Gram-negative bacterium DBS0350092 nrampB- nrampB decreased defense response to Gram-negative bacterium | delayed aggregation DBS0350093 nrampB-/nramp1- nramp1 | nrampB increased number of tip-organizers | decreased defense response to Gram-negative bacterium | delayed aggregation HM1060 nsfA(A1847G, A1939T, T1977C, T2005G, A2025T, A2366T) nsfA decreased rate of endocytosis | decreased phagocytosis | abolished cell motility | decreased actin filament polymerization at leading edge HM1067 nsfA(A1854T, T1984A, C2131A, A2398T, T2574A) nsfA decreased rate of endocytosis | abolished cell motility | decreased cell motility | aberrant hypotonic response | decreased actin filament polymerization at leading edge | increased phagocytosis DBS0236955 nxnA- nxnA decreased lysosomal protein degradation | decreased culmination | decreased growth rate | delayed development | decreased chemotaxis to cAMP DBS0351164 nxnA- nxnA aberrant cellular response to stress DBS0236702 nxnA-/[act15]:GFP:nxnB nxnA | nxnB development arrests at mound stage DBS0350857 odc- odc aberrant cellular metabolic process | aberrant cell cycle | abolished vegetative growth DBS0236704 osbA- osbA increased slug migration | precocious development DBS0238357 p2xA- p2xA aberrant hypotonic response DBS0304487 p2xA- p2xA wild type DBS0350312 p2xA- p2xA aberrant contractile vacuole organization | abolished hypotonic response | decreased contractile vacuole size | aberrant regulation of GTPase activity DBS0350484 p2xA-/AX2 p2xA wild type | aberrant contractile vacuole discharge DBS0350485 p2xA-/AX4 p2xA aberrant contractile vacuole discharge | aberrant hypotonic response DBS0238362 p2xA-/[act15]:p2xA:GFP p2xA wild type DBS0350315 p2xA-/p2xA(K67A/K289A) p2xA abolished hypotonic response DBS0350314 p2xA-/p2xA(R285K) p2xA decreased hypotonic response DBS0350313 p2xA-/p2xA(R63A) p2xA precocious hypotonic response DBS0306169 p2xA-/p2xB-/p2xC-/p2xD-/p2xE- p2xA | p2xB | p2xC | p2xD | p2xE delayed hypotonic response | decreased growth rate DBS0306166 p2xB- p2xB wild type DBS0306167 p2xC- p2xC wild type DBS0306168 p2xD- p2xD wild type DBS0304486 p2xE- p2xE wild type DBS0304465 padA(1-276) padA aberrant aggregation | decreased cell-cell adhesion | decreased gene expression | development arrests at slug stage | delayed aggregation | aberrant stalk cell differentiation | aberrant chemotaxis to cAMP | aberrant stream morphology | aberrant fruiting body morphogenesis | delayed development DBS0350013 pah- pah abolished catalytic activity | abolished vegetative growth DBS0350014 pah-/[act15]:6xHis:pah pah wild type DBS0350016 pah-/[act15]:6xHis:pah(92-415) pah abolished vegetative growth DBS0350015 pah-/[act15]:6xHis:pah(92-441) pah wild type DBS0236705 pakA- pakA aberrant cytokinesis | delayed development | decreased myosin II assembly DBS0236706 pakA- pakA wild type DBS0349885 pakA- pakA delayed development | decreased chemotaxis to cAMP | increased bleb assembly DBS0236707 pakA-/[act15]:pakA pakA wild type DBS0350810 pakA-/[act15]:pakA(T579A) pakA decreased chemotaxis to cAMP DBS0349889 pakA-/[act15]:pakA:GFP pakA wild type DBS0236709 pakB- pakB decreased growth rate | decreased bleb assembly DBS0236708 pakB- pakB abolished establishment of cell polarity | decreased lateral pseudopodium retraction DBS0236712 pakB-/[act15]:GFP-pak(1-600) pakB abolished cytokinesis DBS0236710 pakB-/[act15]:GFP-pakB(1-337:563-851) pakB abolished cytokinesis | increased pinocytosis | increased phagocytosis DBS0350428 pakB-/[act15]:RFP:abpE abpE-1 | abpE-2 | pakB decreased chemotaxis to cAMP | aberrant establishment or maintenance of cell polarity | abolished aggregation | abolished protein localization to leading edge DBS0350430 pakB-/[act15]:RFP:abpE/[act15]:GFP:pak(1-180) abpE-1 | abpE-2 | pakB wild type DBS0236715 pakB-/pakC- pakB | pakC decreased chemotaxis rate DBS0236717 pakC(K121H/E124L) pakC abolished protein binding DBS0236719 pakC(R34C) pakC decreased lateral pseudopodium retraction | decreased chemotaxis rate DBS0236720 pakC(S466A/P470A) pakC decreased lateral pseudopodium retraction | decreased chemotaxis rate DBS0236716 pakC- pakC decreased lateral pseudopodium retraction | decreased bleb assembly | decreased chemotaxis rate DBS0350281 pakD- pakD aberrant cellular homeostasis | aberrant filopodium formation | aberrant actin cytoskeleton organization | abolished negative regulation of vegetative growth | abolished aggregation | aberrant actin filament polymerization | aberrant establishment or maintenance of cell polarity | decreased chemotaxis to cAMP | increased growth rate | aberrant cellular response to extracellular stimulus | abolished positive regulation of chemorepellant activity DBS0350282 pakD-/[act15]:pakD pakD development arrests at mound stage DBS0350395 pakD-/[act15]:pakD:GFP pakD wild type HC392 patB- patB abolished vegetative growth DBS0236726 pats1- pats1 aberrant cytokinesis DBS0350097 pats1- pats1 aberrant cytokinesis LAS45 pats1- pats1 decreased socially cooperative development DBS0236727 pats1-/[act15]:GFP:pats1(2087-2351) pats1 aberrant cytokinesis DBS0236728 paxB- paxB decreased exocytosis | decreased cell-substrate adhesion | abolished slug migration | increased chemotaxis to cAMP | development arrests at mound stage | decreased prespore gene expression | aberrant fruiting body morphogenesis | decreased cell migration to prestalk region | increased phagocytosis DBS0304926 paxB- paxB aberrant cell separation during cytokinesis | decreased cell-substrate adhesion | aberrant cytokinesis | decreased cell motility DBS0304930 paxB-/[act15]:GFP:paxB paxB wild type DBS0350973 paxB-/[act15]:gpaH gpaH | paxB aberrant cytokinesis DBS0350094 paxB-/[act15]:pldB paxB | pldB wild type | increased phagocytosis DBS0236730 paxB-/[ecmA]:paxB:GFP paxB decreased cell migration to prestalk region DBS0236732 paxB-/[pspA]:paxB:GFP paxB decreased cell migration to prestalk region DBS0304929 paxB-/mhcA- mhcA | paxB aberrant cytokinesis DBS0236733 pcp- pcp wild type | aberrant hypotonic response DBS0236734 pde4- pde4 decreased culmination | abolished stream development | delayed slug development | increased number of early culminant tips | increased protein level | delayed culmination DBS0236735 pde4-/[act15]:pde4:GFP pde4 wild type DBS0235991 pdeD- pdeD decreased 3',5'-cyclic-GMP phosphodiesterase activity DBS0236736 pdeD- pdeD aberrant calcium-mediated signaling DBS0350517 pdeD- pdeD decreased 3',5'-cyclic-GMP phosphodiesterase activity | increased fruiting body size | aberrant stream morphology DBS0351194 pdeD- pdeD decreased protein localization to cell cortex | abolished protein localization to cell cortex | aberrant chemotaxis to cAMP | aberrant actin filament polymerization | decreased myosin II assembly | increased activation of GTPase activity DBS0350518 pdeD-/[act15]:pdeD:YFP pdeD wild type DBS0235992 pdeD-/pdeE- pdeD | pdeE decreased protein localization to cell cortex | decreased 3',5'-cyclic-GMP phosphodiesterase activity | decreased 3',5'-cyclic-AMP phosphodiesterase activity | decreased lateral pseudopodium formation | increased protein kinase activation DBS0350893 pdeD-/pdeE-/[unk]:pdeE pdeD | pdeE delayed aggregation DBS0350900 pdeE- pdeE increased oscillatory cAMP signaling | abolished 3',5'-cyclic-AMP phosphodiesterase activity DBS0235993 pdeE- pdeE decreased 3',5'-cyclic-AMP phosphodiesterase activity | aberrant chemotaxis to cAMP DBS0236740 pdiA- pdiA decreased mound size | aberrant oscillatory cAMP signaling | decreased fruiting body size DBS0350797 pdkA- pdkA aberrant macropinocytosis | decreased protein kinase activation DBS0350817 pdkA- pdkA decreased mound size | decreased protein kinase activation DBS0350799 pdkA-/pdkB- pdkA | pdkB aberrant chemotaxis to cAMP | development arrests at mound stage | decreased protein kinase activation | decreased establishment of cell polarity DBS0350819 pdkA-/pdkB- pdkA | pdkB aberrant sorocarp development DBS0350798 pdkB- pdkB increased macropinocytosis DBS0350818 pdkB- pdkB decreased mound size DBS0237029 pdsA- pdsA aberrant chemotaxis to cAMP | aberrant stream morphology UK7 pdsA- pdsA decreased 3',5'-cyclic-AMP phosphodiesterase activity | decreased gene expression | aberrant sorocarp development | abolished aggregation HPX235 pdsA- pdsA abolished catalytic activity | abolished aggregation DBS0236741 pefA- pefA wild type DBS0236742 pefA-/pefB- pefA | pefB wild type DBS0236744 pefB- pefB wild type DBS0236745 pefB-/cybA- cybA | pefB wild type DBS0236746 pefB-/noxA- noxA | pefB wild type DBS0236747 pefB-/noxA-/[act15]:pefB noxA | pefB aberrant sorocarp development DBS0236748 pefB-/noxB- noxB | pefB wild type DBS0236749 pefB-/noxC- noxC | pefB abolished sporulation | aberrant sorocarp development HW260 pgtA- pgtA increased vegetative cell size DBS0305022 pgtB- pgtB aberrant cellular metabolic process | aberrant spore coat morphology | aberrant hyperosmotic response DBS0305024 pgtB-/pgtC- pgtB | pgtC aberrant cellular metabolic process | aberrant spore coat morphology | aberrant hyperosmotic response DBS0305023 pgtC- pgtC aberrant cellular metabolic process | aberrant hyperosmotic response DBS0236752 phdA- phdA decreased actin filament polymerization | decreased mound size | decreased chemotaxis rate | decreased fruiting body size DBS0236753 phdA-/[act15]:phdA phdA wild type DBS0236754 phdA-/[act15]:phdA:GFP phdA wild type DBS0350865 phdG- phdG decreased chemotaxis to cAMP DBS0236755 phg1A- phg1A increased secretion of lysosomal enzymes | decreased lysosomal protein degradation | decreased protein level | decreased cell-substrate adhesion | decreased gene expression | aberrant defense response to bacterium | aberrant cytokinesis | decreased phagocytosis | abolished defense response to bacterium | decreased growth rate | development arrests at slug stage | decreased protein localization to cell surface | aberrant phagocytosis | increased lysosomal pH | decreased protein stabilization DBS0351549 phg1A- phg1A decreased cell-substrate adhesion | decreased phagocytosis DBS0236757 phg1A-/[act15]:kil1 kil1 | phg1A decreased lysosomal protein degradation | increased secretion of lysosomal enzymes | wild type | increased lysosomal pH | decreased protein stabilization DBS0304869 phg1A-/[act15]:phg1A(1-276):phg1B221-587) phg1A | phg1B decreased phagocytosis DBS0304868 phg1A-/[act15]:phg1B phg1A | phg1B increased secretion of lysosomal enzymes | wild type | decreased cell-substrate adhesion | aberrant protein level | decreased phagocytosis DBS0304870 phg1A-/[act15]:phg1B(1-220):phg1a(277-642) phg1A | phg1B decreased phagocytosis DBS0304872 phg1A-/phg1B- phg1A | phg1B increased secretion of lysosomal enzymes | decreased cell-substrate adhesion | decreased phagocytosis | decreased growth rate | development arrests at tipped mound stage | abolished culmination DBS0304866 phg1B- phg1B increased secretion of lysosomal enzymes | decreased protein level | decreased phagocytosis | decreased growth rate | abolished culmination DBS0236758 phg2- phg2 decreased cell-substrate adhesion | decreased phagocytosis | aberrant cytokinesis | decreased cell motility | aberrant cell morphology | aberrant actin filament organization | precocious development | precocious gene expression | aberrant response to nutrient DBS0238400 phg2- phg2 increased filopodium formation | increased actin filament polymerization | increased cell-substrate adhesion | decreased chemotaxis to cAMP | aberrant cell morphology | increased phagocytosis DBS0350578 phg2- phg2 abolished gene expression | decreased protein phosphorylation | aberrant protein localization to nucleus DBS0236760 phg2-/[act15]:GFP:phg2(199-1389) phg2 decreased phagocytosis DBS0237615 phg2-/[act15]:gbpD gbpD | phg2 aberrant cell morphology | abolished chemotaxis to cAMP | increased pseudopodium formation DBS0350580 phg2-/[act15]:myc:ptpC phg2 | ptpC abolished protein phosphorylation HG1648 phgA- phgA increased contractile vacuole size | aberrant contractile vacuole organization | aberrant hypotonic response | aberrant pore formation during contractile vacuole discharge DBS0302610 phgA-/[OE]:dsgg dsgg | phgA aberrant contractile vacuole organization DBS0236761 phgA-/lvsA-/[act6]:GFP:lvsA lvsA | phgA aberrant protein localization to contractile vacuole DBS0236762 phlp1- phlp1 decreased response to cAMP | aberrant regulation of protein modification | abolished chemotaxis to folate | decreased growth rate | abolished protein localization to plasma membrane | decreased cGMP-mediated signaling | abolished aggregation | abolished chemotaxis to cAMP DBS0236763 phlp1-/[OE]:phpl1 phlp1 wild type DBS0236764 phlp3- phlp3 wild type DBS0350824 phr- phr aberrant chemotaxis to cAMP | delayed development HW288 phyA- phyA abolished sporulation | abolished stalk development | abolished peptidyl-proline hydroxylation | abolished culmination | increased response to hypoxia DBS0266771 phyA-/[ecmA]:phyA(D132N):myc phyA decreased peptidyl-proline hydroxylation DBS0266770 phyA-/[ecmA]:phyA(R276A):myc phyA abolished peptidyl-proline hydroxylation | abolished culmination piaA(G917D) piaA DBS0236769 piaA(G917D)/[act15]:piaA piaA delayed aggregation DBS0351455 piaA(G917D)/[unk]:GFP:piaA(G963E) piaA abolished aggregation DBS0350882 piaA(G917D)/acrA- acrA | piaA abolished gene expression | abolished establishment of cell polarity | abolished chemotaxis to cAMP DBS0350877 piaA(G917D)/hephA- hephA | piaA increased response to cAMP | wild type | abolished activation of adenylate cyclase activity | decreased cAMP level DBS0236767 piaA- piaA aberrant activation of adenylate cyclase activity DBS0236770 piaA- piaA aberrant cytokinesis DBS0236771 piaA- piaA abolished aggregation | decreased myosin II assembly | increased phagocytosis DBS0304637 piaA- piaA decreased cell motility | decreased chemotaxis rate | decreased establishment of cell polarity | aberrant protein tyrosine phosphorylation DBS0351319 piaA- piaA decreased taxis DBS0349879 piaA- piaA decreased protein phosphorylation | decreased protein kinase activity | abolished protein phosphorylation | decreased chemotaxis to cAMP | aberrant protein localization to plasma membrane | increased activation of GTPase activity | abolished positive regulation of chemorepellant activity DBS0351403 piaA- piaA aberrant cytokinesis DBS0236779 pik6- pik6 decreased gene expression | abolished aggregation DBS0236772 pikA- pikA wild type DBS0236766 pikA-/pikB- pikA | pikB aberrant negative chemotaxis | decreased response to bacterium | decreased actin filament polymerization | decreased activation of GTPase activity | abolished protein localization to plasma membrane | aberrant chemotaxis to cAMP | decreased cell motility | abolished protein kinase activation | abolished protein localization to trailing edge | decreased chemotaxis to folate | decreased chemotaxis to cAMP | decreased myosin II assembly DBS0236773 pikA-/pikB- pikA | pikB abolished stream development | decreased pinocytosis | aberrant aggregation | decreased exocytosis | aberrant activation of adenylate cyclase activity | aberrant macropinocytosis | abolished protein localization to plasma membrane | delayed aggregation | decreased spore cell differentiation | increased cAMP level | abolished vegetative growth | aberrant sorocarp development | aberrant phagolysosome formation | aberrant phagosome maturation | decreased phosphatidylinositol biosynthesis | aberrant fruiting body morphogenesis | aberrant actin filament organization | aberrant cell morphology HM1141 pikA-/pikB- pikA | pikB decreased pinocytosis | decreased growth rate | decreased cell motility | decreased taxis DBS0350471 pikA-/pikB-/[act15]:GFP:cap cap | pikA | pikB wild type DBS0252703 pikA-/pikB-/pikC- pikA | pikB | pikC decreased protein localization to leading edge | increased cell motility HM1200 pikA-/pikB-/pikC-/pikF-/pikG- pikA | pikB | pikC | pikF | pikG aberrant aggregation | decreased pinocytosis | decreased protein tyrosine phosphorylation | increased chemotaxis to folate | aberrant macropinocytosis | decreased growth rate | decreased phagocytosis | decreased cell motility | increased bleb assembly | decreased chemotaxis to cAMP | aberrant protein localization to plasma membrane | aberrant signal transduction HM1284 pikA-/pikB-/pikC-/pikF-/pikG-/pikH- pikA | pikB | pikC | pikF | pikG | pikH decreased defense response to Gram-negative bacterium | decreased cell motility HM1295 pikA-/pikB-/pikC-/pikF-/pikG-/pten- pikA | pikB | pikC | pikF | pikG | pten aberrant aggregation | decreased defense response to Gram-negative bacterium | decreased growth rate | decreased cell motility | increased resistance to N-Phenylthiourea DBS0238073 pikA-/pikB-/plaA- pikA | pikB | plaA decreased actin filament polymerization | delayed aggregation | aberrant chemotaxis to cAMP | abolished positive chemotaxis DBS0236774 pikB- pikB wild type DBS0236776 pikC- pikC wild type DBS0236777 pikD1 pikD abolished slug migration | delayed aggregation | decreased mound size | aberrant fruiting body morphogenesis | decreased sporulation DBS0236778 pikE- pikE wild type HM1241 pikF- pikF decreased pinocytosis | decreased growth rate | aberrant pinosome maturation LAS31 pikG- pikG aberrant socially cooperative development HM1513 pikI- pikI decreased catalytic activity | decreased actin filament polymerization | decreased growth rate | aberrant chemotaxis to cAMP | decreased cGMP-mediated signaling | aberrant calcium-mediated signaling | decreased protein kinase activation | increased bleb assembly DBS0350828 pinA-/[ecmAO]:lacZ pinA aberrant prestalk cell differentiation DBS0350827 pinA-/[pspA]:lacZ pinA aberrant prespore cell differentiation DBS0351429 pip5k3-/AX2 pip5k3 decreased defense response to Gram-negative bacterium | aberrant defense response to bacterium | aberrant phagosome maturation | decreased protein processing in phagocytic vesicle | decreased protein localization to phagocytic vesicle DBS0351428 pip5k3-/AX3 pip5k3 aberrant macropinocytosis | decreased growth rate SB16 pirA- pirA decreased vegetative cell size | increased cell motility SB3 pirA- pirA increased actin filament polymerization | increased vegetative cell size | decreased cell motility | aberrant cellular response to stress | increased pseudopodium formation DBS0351205 pirA- pirA decreased cell motility | aberrant pseudopodium formation | abolished protein level DBS0351533 pirA-/AX2 pirA decreased protein level | aberrant macropinocytosis | aberrant cytokinesis | increased vegetative cell size | decreased cell motility | decreased pseudopodium formation | increased bleb assembly | decreased filopodium formation DBS0351206 pirA-/pirA(K193D/R194D):EGFP pirA abolished protein localization to cell periphery | decreased protein phosphorylation DBS0349901 pisA- pisA increased gene expression | precocious development | decreased fruiting body size | aberrant prestalk cell differentiation DBS0236783 pkaC- pkaC abolished gene expression | increased protein phosphorylation | aberrant response to abiotic stimulus | decreased protein level | decreased gene expression | decreased activation of GTPase activity | abolished catalytic activity | aberrant response to cAMP | increased cellular thermotolerance | aberrant myosin II filament organization | decreased protein kinase activation | abolished aggregation | aberrant actin filament organization | aberrant protein localization to plasma membrane | aberrant protein localization to cell cortex | abolished chemotaxis to cAMP | increased protein kinase activation | increased activation of GTPase activity | abolished positive regulation of chemorepellant activity DBS0350694 pkaC-/[act15]:pkaC pkaC abolished culmination DBS0350708 pkaC-/[act6]:pkaC(303-648) pkaC wild type DBS0350707 pkaC-/[act6]:pkaC(330-648) pkaC abolished aggregation DBS0350710 pkaC-/[dscC]:LUC pkaC decreased gene expression | increased macropinocytosis DBS0236782 pkaC-/gdt1- gdt1 | pkaC increased gene expression | abolished aggregation HTY217 pkaR(A31T) pkaR abolished protein kinase activation | precocious development DBS0235411 pkaR- pkaR abolished stream development | increased resistance to valproic acid | decreased spore germination | aberrant extracellular cAMP signaling pathway | aberrant response to lithium | increased gene expression | precocious sporulation | increased lateral pseudopodium formation | aberrant chemotaxis to cAMP | decreased cell motility | decreased fruiting body size | aberrant cell morphology DBS0351315 pkbA- pkbA decreased macropinocytosis DBS0236784 pkbA- pkbA decreased pinocytosis | decreased protein phosphorylation | aberrant macropinocytosis | decreased bleb assembly | abolished protein kinase activation | abolished protein localization | abolished protein localization to trailing edge | aberrant phagosome maturation | increased phagocytosis | decreased myosin II assembly DBS0349876 pkbA- pkbA aberrant cellular response to extracellular stimulus | increased protein kinase activation DBS0350113 pkbA-/[act15]:GFP:rheb(Q64L) pkbA | rheb decreased phagocytosis DBS0236785 pkbA-/pkgB- pkbA | pkgB aberrant chemotaxis to cAMP | abolished vegetative growth | decreased chemotaxis rate | abolished protein phosphorylation | abolished aggregation | aberrant cellular response to extracellular stimulus | increased activation of GTPase activity | increased protein kinase activation DBS0304640 pkbA-/pkgB- pkbA | pkgB aberrant cell motility | abolished vegetative growth DBS0351317 pkbA-/pkgB- pkbA | pkgB aberrant macropinocytosis | abolished vegetative growth | abolished macropinocytosis DBS0350916 pkcA- pkcA decreased cell-cell adhesion | decreased protein level | increased chemotaxis to cAMP | decreased gene expression | increased number of mound tips | increased actin filament polymerization | aberrant oscillatory cAMP signaling | decreased fruiting body size | abolished positive regulation of chemorepellant activity DBS0350918 pkcA- pkcA aberrant aggregation | decreased catalytic activity | aberrant cytokinesis | aberrant sorocarp development DBS0350919 pkcA-/[act15]:pldB pkcA | pldB aberrant aggregation | decreased sporulation DBS0350917 pkcA-/[ecmA]:GFP pkcA aberrant prestalk gene expression DBS0350475 pkd2- pkd2 increased resistance to naringenin | decreased growth rate DBS0350367 pkd2- pkd2 aberrant cellular response to fluid shear stress | aberrant exocytosis DBS0351540 pkd2-/AX2 pkd2 aberrant calcium-mediated signaling DBS0351542 pkd2-/iplA- iplA | pkd2 aberrant calcium-mediated signaling DBS0236786 pkgB- pkgB decreased protein phosphorylation | development arrests at mound stage | abolished spore cell differentiation DBS0350328 pkgB- pkgB aberrant sorocarp development DBS0351316 pkgB- pkgB decreased macropinocytosis DBS0304638 pkgB- pkgB decreased cell-substrate adhesion | development arrests at mound stage | decreased chemotaxis rate | decreased taxis | increased cell motility | increased bleb assembly DBS0236787 pkgB-/[act15]:pkbA pkbA | pkgB wild type DBS0236789 pkgB-/[act15]:pkgB(K182M) pkgB development arrests at mound stage DBS0350329 pkgB-/[emcB]:lacZ pkgB abolished prestalk gene expression DBS0236790 pkgB-/[gbfA]:pkbA pkbA | pkgB wild type DBS0236791 pkgB-/[gbfA]:pkgB pkgB wild type DBS0350319 pks17- pks17 decreased fatty acid level | increased gene expression | delayed development | decreased fruiting body size LAS44 pks2- pks2 decreased socially cooperative development LAS19 pks26- pks26 aberrant socially cooperative development DBS0238068 plaA- plaA aberrant chemotaxis to cAMP | abolished aggregation | abolished positive regulation of chemorepellant activity DBS0238067 plaA- plaA abolished aggregation DBS0306196 plaA- plaA aberrant chemotaxis to cAMP | decreased bleb assembly | decreased necrotic cell death DBS0350831 plaA-/piaA- piaA | plaA decreased taxis | decreased chemotaxis to cAMP | aberrant actin filament organization DBS0350486 plaA-/sgcA- plaA | sgcA aberrant chemotaxis to cAMP DBS0350487 plaA-/sgcA-/pkgB- pkgB | plaA | sgcA aberrant chemotaxis to cAMP DG1067 plbG- plbG decreased stalk width | decreased stalk length HAD236 plc- plc decreased protein localization to plasma membrane | aberrant chemotaxis to cAMP | decreased protein localization to cytoplasm | decreased protein kinase activation | abolished aggregation HD1.19 plc- plc aberrant negative chemotaxis HD10 plc- plc aberrant cellular homeostasis | wild type | aberrant spore germination DBS0267125 plc-/[OE]:dagA(PH):GFP/[OE]:plc dagA | plc increased protein localization to plasma membrane | decreased chemotaxis to cAMP DBS0350047 plc-/[act15]:pten:GFP plc | pten wild type | aberrant protein localization to cytoplasm DBS0236796 pldB- pldB decreased catalytic activity | precocious aggregation DBS0236797 pldB-/[act15]:pldB:GFP pldB abolished aggregation DBS0350604 pldB-/[unk]:GFP pldB increased cell migration to prestalk region DBS0350605 pldB-/[unk]:lacZ pldB increased cell migration to prestalk region DBS0236799 plip- plip delayed aggregation DBS0351187 plnA- plnA aberrant defense response to bacterium DBS0350007 png- png delayed aggregation | decreased mound size | aberrant fruiting body morphogenesis DBS0350492 png-/[ecmAO]:lacZ png aberrant prestalk cell differentiation DBS0350491 png-/[ecmA]:lacZ png aberrant prestalk A cell differentiation DBS0350493 png-/[pspA]:lacZ png decreased prespore cell differentiation DBS0236820 ponA- ponA precocious aggregation | decreased actin nucleation | aberrant sorocarp development | aberrant pseudopodium formation DBS0236821 ponA- ponA precocious aggregation | decreased actin nucleation | aberrant sorocarp development | aberrant pseudopodium formation DG1057 potA- potA aberrant fruiting body morphogenesis DBS0351064 poxA- poxA aberrant defense response to bacterium DBS0236824 ppk1- ppk1 decreased growth rate | decreased phagocytosis | decreased fruiting body size | delayed culmination | decreased sporulation ASH01 ppk1- ppk1 aberrant cellular homeostasis | decreased ATP level | decreased growth rate | aberrant spore germination | aberrant macromolecule biosynthesis | decreased fruiting body size | increased growth rate DBS0351356 ppk1-/[act15]:GFP:hsp48 hsp48 | ppk1 decreased protein level DBS0236825 ppk1-/[act15]:ppk1 ppk1 wild type DBS0238099 ppp4C- ppp4c development arrests at mound stage | delayed development DBS0238110 ppp4C-/[act15]:smkA ppp4c | smkA development arrests at mound stage | delayed development DBS0238033 proC- proC increased lateral pseudopodium formation | decreased chemotaxis rate | decreased establishment of cell polarity DBS0238034 proC-/[unk]:FLAG:proC proC wild type DBS0266716 pscA- pscA wild type DBS0266803 psenA- psenA aberrant culmination | decreased prespore cell differentiation DBS0350302 psenA- psenA decreased prespore cell differentiation | aberrant calcium-mediated signaling DBS0350304 psenA-/psenB- psenA | psenB increased gene expression | abolished prespore cell differentiation | development arrests at mound stage | increased protein modification | decreased phagocytosis | aberrant calcium-mediated signaling | increased cAMP level | aberrant sorocarp development | decreased macropinocytosis | aberrant phagosome maturation | decreased protein processing in phagocytic vesicle | decreased prestalk gene expression | decreased stalk cell differentiation DBS0350305 psenA-/psenB-/[act15]:GFP:psenB psenA | psenB wild type DBS0350306 psenA-/psenB-/[act15]:psenB(D348A/D394A) psenA | psenB wild type DBS0350295 psenB- psenB decreased phagocytosis | abolished catalytic activity DBS0350303 psenB- psenB decreased prespore cell differentiation | aberrant calcium-mediated signaling DBS0351095 psenB- psenB aberrant response to chemical DBS0350298 psenB-/psenA- psenA | psenB aberrant culmination | decreased phagocytosis | abolished catalytic activity | decreased prespore cell differentiation HOK2 psiA- psiA abolished prespore cell division DBS0351581 psiA-/[ecmB]:lacZ psiA precocious prestalk gene expression DBS0351578 psiA-/[rnrB]:lacZ psiA aberrant prespore gene expression DBS0236021 psiM- psiM wild type DBS0236022 psiM- psiM wild type DBS0236828 pslA- pslA abolished sporulation | increased mound size | decreased sorus size | aberrant prestalk gene expression | increased stalk length | abolished stalk cell differentiation | abolished prespore gene expression DBS0236829 psmC1- psmC1 increased resistance to spectinomycin | aberrant standing slug morphology | abolished slug migration | increased vegetative cell size HW70 pspB- pspB aberrant spore coat morphology | precocious spore germination DBS0302352 psrA- psrA decreased culmination | increased protein phosphorylation | decreased activation of GTPase activity | delayed prestalk gene expression | decreased cell motility | delayed development | increased protein kinase activation DBS0351094 psrA- psrA aberrant response to chemical DBS0302356 psrA-/[act15]:FLAG:gskA gskA | psrA increased protein kinase activation DBS0302353 psrA-/[act15]:ecmA:lacZ psrA aberrant prestalk gene expression DBS0302354 psrA-/[act15]:ecmB:lacZ psrA aberrant prestalk gene expression DBS0302357 psrA-/[act15]:gskA(K84M/K85M) gskA | psrA decreased culmination | decreased prespore gene expression | delayed development | increased protein kinase activation DBS0302355 psrA-/[act15]:psrA psrA wild type DBS0350829 psrA-/[unk]:FLAG:rasD(G12T) psrA | rasD increased protein kinase activation HM1289 pten- pten aberrant cell motility | decreased lateral pseudopodium retraction | decreased cell motility | decreased macropinocytosis | abolished aggregation | decreased chemotaxis to cAMP DBS0236830 pten- pten decreased response to Gram-negative bacterium | decreased positive regulation of GTPase activity | decreased actin filament polymerization | decreased lateral pseudopodium retraction | abolished protein localization to plasma membrane | decreased growth rate | increased actin filament polymerization | decreased phagocytosis | decreased bleb assembly | decreased cell motility | increased protein localization to plasma membrane | decreased chemotaxis to cAMP | abolished aggregation | aberrant pseudopodium formation | increased pseudopodium formation | aberrant signal transduction | abolished positive regulation of chemorepellant activity DBS0349884 pten- pten aberrant cytokinesis | increased protein kinase activity | decreased chemotaxis to cAMP | decreased establishment of cell polarity DBS0350660 pten- pten decreased uropod retraction | decreased protein localization to cleavage furrow | decreased growth rate | aberrant cytokinesis | decreased protein localization to pseudopodium DBS0350454 pten-/[act15]:lpten:RFP lpten | pten wild type DBS0349890 pten-/[act15]:pakA:GFP pakA | pten aberrant cytokinesis DBS0350754 pten-/[act15]:pten(186-515):GFP pten aberrant sorocarp development | decreased chemotaxis to cAMP DBS0350755 pten-/[act15]:pten(C124S):GFP pten aberrant sorocarp development | decreased chemotaxis to cAMP DBS0351587 pten-/[act15]:pten(G129E) pten increased lateral pseudopodium formation | aberrant localization DBS0236831 pten-/[act15]:pten:GFP pten wild type DBS0349888 pten-/gefS- gefS | pten aberrant cytokinesis | decreased chemotaxis to cAMP DBS0349891 pten-/pakA- pakA | pten decreased chemotaxis to cAMP DBS0349893 pten-/pakA-/[act15]:pakA(T585A):GFP pakA | pten decreased chemotaxis to cAMP DBS0349900 pten-/pakA-/[act15]:pakA(T585E):GFP pakA | pten aberrant cytokinesis | decreased chemotaxis to cAMP DBS0349899 pten-/pakA-/[act15]:pakA:GFP pakA | pten aberrant cytokinesis DBS0349887 pten-/piaA- piaA | pten decreased protein kinase activity | decreased chemotaxis to cAMP DBS0349880 pten-/pkbA- pkbA | pten decreased chemotaxis to cAMP DBS0349886 pten-/pkgB- pkgB | pten aberrant cytokinesis | increased protein kinase activation DBS0236832 ptpA1- ptpA1-1 | ptpA1-2 decreased prespore cell differentiation | precocious development | increased prestalk O cell differentiation DBS0236833 ptpB- ptpB increased migratory slug size DBS0350675 ptpB-/[act15]:6xHis:erkA erkA | ptpB aberrant stream morphology DBS0236834 ptpC+/- ptpC aberrant cytokinesis | decreased growth rate DBS0236835 pufA- pufA increased protein kinase activity | aberrant fruiting body morphogenesis | increased protein level | precocious development DBS0304391 pyk3- pyk3 increased prespore gene expression | decreased prestalk gene expression | increased prespore cell differentiation | delayed culmination DBS0350577 pyk3- pyk3 decreased protein phosphorylation | decreased gene expression | aberrant protein localization to nucleus DBS0350581 pyk3- pyk3 decreased protein phosphorylation | decreased gene expression DBS0304393 pyk3-/[act15]:T7:pyk3 pyk3 wild type DBS0350579 pyk3-/phg2- phg2 | pyk3 abolished gene expression | decreased protein phosphorylation | aberrant protein localization to nucleus DBS0236836 pykA- pykA decreased growth rate | abolished aggregation DBS0236837 pyr56- pyr56 increased resistance to 5-Fluoroorotic acid | abolished uracil biosynthetic process DBS0236838 pyr56- pyr56 increased resistance to 5-Fluoroorotic acid | abolished uracil biosynthetic process DBS0351499 pzoA- pzoA aberrant cellular response to fluid shear stress | aberrant chemotaxis to cAMP DBS0350017 qdpr- qdpr decreased spore germination | decreased growth rate | abolished catalytic activity | aberrant response to oxidative stress DBS0350018 qdpr-/[act15]:pah pah | qdpr decreased growth rate DBS0236839 qkgA- qkgA-1 | qkgA-2 increased mound size | delayed aggregation | aberrant vegetative growth | aberrant nucleus organization | increased growth rate | abolished negative chemotaxis DBS0351552 qkgA- qkgA-1 | qkgA-2 aberrant aggregation | decreased actin filament polymerization | aberrant cytokinesis | decreased cell motility | decreased chemotaxis to cAMP DBS0350011 qkgA-/[act15]:bzpN:GFP bzpN | qkgA-1 | qkgA-2 abolished negative regulation of vegetative growth DBS0351560 qtrt1- qtrt1 aberrant response to stimulus DBS0350263 rab7A- rab7A decreased growth rate DBS0236841 racB- racB decreased actin filament polymerization | delayed aggregation | aberrant fruiting body morphogenesis | decreased chemotaxis rate | decreased myosin II assembly DBS0236842 racC- racC decreased protein localization to plasma membrane | decreased actin filament polymerization | aberrant cytokinesis | aberrant stream morphology | decreased chemotaxis rate | aberrant cell morphology | aberrant protein localization DBS0350272 racC- racC aberrant cytokinesis | decreased growth rate | abolished positive regulation of chemorepellant activity DBS0237191 racC-/[act15]:CFP:racC racC increased actin filament polymerization DBS0235413 racE- racE abolished cytokinesis | aberrant cortical actin cytoskeleton organization | abolished protein localization to cell cortex DBS0350271 racE- racE decreased protein phosphorylation | increased lateral pseudopodium formation | aberrant cytokinesis | delayed aggregation | decreased growth rate | aberrant regulation of GTPase activity | aberrant protein localization to plasma membrane | decreased establishment of cell polarity | decreased chemotaxis to cAMP DBS0351308 racE- racE aberrant cortical actin cytoskeleton organization | abolished protein localization to cell cortex | aberrant cytokinesis | decreased cell motility | aberrant cell morphology DBS0351348 racE-/[act15]:GFP:racE(G20V) racE decreased protein phosphorylation | decreased chemotaxis to cAMP DBS0351349 racE-/[act15]:GFP:racE(G23V) racE increased protein phosphorylation DBS0351350 racE-/[act15]:GFP:racE(S192D) racE increased protein phosphorylation | wild type DBS0351347 racE-/[act15]:GFP:racE(T25N) racE wild type DBS0351614 racE-/[act15]:GFP:racE(T25N/S192D) racE wild type DBS0351351 racE-/[act15]:GFP:rasC(Q62L) racE | rasC decreased protein phosphorylation DBS0349949 racE-/[act15]:fttB fttB | racE decreased growth rate DBS0349946 racE-/[act15]:fttB:GFP fttB | racE abolished protein localization to cell cortex DBS0350956 racE-/[act15]racE(G20V) racE wild type DBS0350957 racE-/[act15]racE(T25N) racE abolished cytokinesis DBS0351505 racF1- racF1 wild type DBS0236844 racF2(G12V) racF2 decreased cell-cell adhesion DBS0236845 racF2(N17T) racF2 increased cell-cell adhesion | decreased sexual fusion DBS0236843 racF2- racF2 increased mound size | increased cell-cell adhesion | decreased sexual fusion DBS0236849 racG- racG decreased cell motility | decreased protein localization to phagocytic vesicle DBS0236850 racH- racH decreased exocytosis | aberrant protein localization to cytoplasmic vesicle | decreased pinocytosis | decreased defense response to Gram-negative bacterium | aberrant defense response to bacterium | decreased defense response to bacterium DBS0351149 rapC- rapC increased number of mound tips | aberrant cytokinesis | increased cell-substrate adhesion | decreased cell motility | aberrant cell morphology DBS0266936 rapgap1- rapgap1 decreased positive regulation of GTPase activity | increased actin filament polymerization | increased cell-substrate adhesion | decreased cell motility | decreased myosin II assembly | increased protein kinase activation DBS0266937 rapgap1-/[act15]:GFP:rapgap1 rapgap1 increased positive regulation of GTPase activity | increased lateral pseudopodium formation | decreased cell-substrate adhesion | increased myosin II assembly | increased actin filament polymerization | increased cell motility DBS0351487 rapgap3- rapgap3 increased cell motility | increased activation of GTPase activity DBS0350864 rapgap3-/AX2 rapgap3 delayed aggregation | decreased chemotaxis to cAMP | decreased fruiting body size DBS0350863 rapgap3-/KAX3 rapgap3 delayed development of tipped mound | increased calcium-dependent cell-cell adhesion | decreased cell motility | aberrant cell migration to prestalk region | aberrant regulation of GTPase activity DBS0350316 rapgap9- rapgap9 increased filopodium formation | increased actin filament polymerization | aberrant cytokinesis | decreased spore size | increased cell-substrate adhesion | decreased chemotaxis to cAMP DBS0350317 rapgap9-/[act15]:GFP:rapgap9 rapgap9 wild type DBS0350628 rapgapB- rapgapB aberrant aggregation | increased cell-substrate adhesion | aberrant regulation of GTPase activity | aberrant actin filament organization DBS0350630 rapgapB-/[ecmAO]:RFP ecmA | rapgapB aberrant cell-cell adhesion DBS0350631 rapgapB-/[ecmA]:lacZ rapgapB aberrant cell migration to prestalk region DBS0350632 rapgapB-/[ecmO]:lacZ rapgapB aberrant cell migration to prestalk region DBS0350629 rapgapB-/[pspA]:RFP pspA | rapgapB aberrant cell-cell adhesion DBS0236852 rasB- rasB decreased growth rate DBS0350836 rasB- rasB decreased phagocytosis | decreased macropinocytosis | aberrant actin filament organization DBS0236853 rasC-/AX2 rasC increased rate of endocytosis | aberrant response to cAMP | decreased cell motility | increased vegetative cell size | abolished protein kinase activation | decreased protein kinase activation | decreased taxis | abolished aggregation | aberrant pseudopodium formation | aberrant actin filament organization | aberrant protein localization to cell cortex | aberrant cellular response to extracellular stimulus DBS0236854 rasC-/JH10 rasC wild type | aberrant gene expression | decreased protein kinase activation | abolished aggregation | abolished chemotaxis to cAMP DBS0237614 rasC-/[act15]:gbpD gbpD | rasC increased cell-substrate adhesion | aberrant cell morphology DBS0350740 rasC-/[rasC]:rasG rasC | rasG abolished activation of adenylate cyclase activity | abolished aggregation DBS0350742 rasC-/[rasC]:rasG(1-77(D30A)):rasC(79-189) rasC | rasG wild type DBS0350741 rasC-/[rasC]:rasG(D30A) rasC | rasG aberrant aggregation | decreased activation of adenylate cyclase activity DBS0236855 rasC-/dmpA- dmpA | rasC abolished stream development DBS0236856 rasC-/pikD1 pikD | rasC increased establishment of cell polarity | increased chemotaxis to cAMP | aberrant gene expression | aberrant fruiting body morphogenesis | decreased protein kinase activation | abolished aggregation DBS0236857 rasC-/rasD- rasC | rasD abolished aggregation DBS0236858 rasC-/rasG- rasC | rasG aberrant cell separation during cytokinesis | wild type | aberrant cell motility | decreased activation of adenylate cyclase activity | decreased gene expression | abolished guanylyl cyclase activity | abolished chemotaxis to folate | decreased growth rate | aberrant chemotaxis to folate | abolished protein kinase activation | abolished vegetative growth | decreased cell motility | increased protein level | abolished aggregation | delayed gene expression | abolished chemotaxis to cAMP | abolished positive regulation of chemorepellant activity DBS0266697 rasC-/rasG-/[act15]:carA carA-1 | carA-2 | rasC | rasG decreased activation of adenylate cyclase activity | abolished activation of GTPase activity | decreased growth rate | abolished vegetative growth | abolished protein kinase activation | abolished cGMP-mediated signaling | abolished chemotaxis to cAMP DBS0350480 rasC-/rasG-/[rasG]:rasD rasC | rasD | rasG decreased chemotaxis to folate DBS0350482 rasC-/rasG-/[rasG]:rasD(1-104):rasG(103-189) rasC | rasD | rasG decreased chemotaxis to folate DBS0350481 rasC-/rasG-/[rasG]:rasG rasC | rasG wild type DBS0350483 rasC-/rasG-/[rasG]:rasG(1-104):rasD(103-187) rasC | rasD | rasG wild type DBS0351062 rasC-/rasG-/[unk]:carA carA-1 | carA-2 | rasC | rasG decreased protein localization to plasma membrane DBS0351449 rasC-/rasS- rasC | rasS increased macropinocytosis DBS0351213 rasC-[act15]:rasG(S17N) rasC | rasG abolished activation of GTPase activity | decreased chemotaxis to cAMP DBS0236860 rasD- rasD aberrant thermotaxis | aberrant phototaxis DBS0351459 rasD-/AX3 rasD increased gene expression | increased prespore cell differentiation DBS0236862 rasG-/AX2 rasG decreased pinocytosis | decreased gene expression | delayed aggregation | aberrant taxis | decreased cGMP-mediated signaling | decreased protein kinase activation | delayed gene expression IR15 rasG-/AX2 rasG aberrant cell separation during cytokinesis | aberrant filopodium formation | decreased actin filament polymerization | decreased growth rate | increased vegetative cell size | decreased macropinocytosis | decreased cell motility | decreased protein kinase activation | decreased establishment of cell polarity | aberrant actin filament organization IR17 rasG-/AX3 rasG aberrant cytokinesis | decreased cell motility | increased vegetative cell size DBS0351460 rasG-/AX3 rasG increased prestalk cell differentiation DBS0236863 rasG-/JH10 rasG aberrant cell separation during cytokinesis | wild type | decreased gene expression | delayed aggregation | abolished activation of GTPase activity | aberrant chemotaxis to folate | decreased growth rate | decreased cGMP-mediated signaling | decreased protein kinase activation | delayed gene expression DBS0236864 rasG-/[OE]:rasB rasB | rasG decreased growth rate DBS0350572 rasG-/[act15]:FLAG:rasG(K169R,K173R,K176R,K178R) rasG aberrant cytokinesis DBS0350571 rasG-/[act15]:FLAG:rasG(K169R,K173R,K176R,K178R,K179R,K180R,K184R) rasG decreased protein modification DBS0350448 rasG-/[dscB]:rasG(S17N) rasG decreased positive regulation of GTPase activity | decreased actin filament polymerization | decreased protein kinase activation | decreased chemotaxis to cAMP DBS0351447 rasG-/rasS- rasG | rasS decreased macropinocytosis DBS0236872 rasS-/AX2 rasS decreased macropinocytosis | decreased cell motility | aberrant pinosome maturation | decreased establishment of cell polarity DBS0351446 rasS-/AX2 rasS aberrant macropinocytosis DBS0236873 rasS-/DH1 rasS decreased rate of endocytosis | decreased growth rate | increased actin filament polymerization | abolished vegetative growth | increased cell motility | aberrant cytoskeleton organization DBS0351314 rasS-/DdB rasS decreased macropinocytosis | increased cell motility DBS0236874 rasZ- rasZ wild type DBS0351598 rbdB- rbdB abolished pre-miRNA processing DBS0350261 rbg3- rbg3 precocious development | increased growth rate DBS0236877 rblA- rblA increased cell migration to prestalk region | decreased spore germination | decreased gene expression | increased gene expression | abolished negative regulation of vegetative growth | decreased growth rate | aberrant vegetative growth | decreased vegetative cell size | precocious development | increased prestalk cell differentiation DBS0349999 rblA-/[act15]:GFP rblA increased cell migration to prestalk region DBS0349996 rblA-/[act15]:GFP/[act15]:myc:btg btg | rblA increased cell migration to prestalk region DBS0349994 rblA-/[btg]:lacZ btg | rblA decreased gene expression DBS0236878 rbrA- rbrA increased gene expression | decreased gene expression | development arrests at slug stage | aberrant prespore gene expression | decreased cell migration to prestalk region | decreased phototaxis | decreased sporulation DBS0236879 rbrA-/[unk]:rbrA rbrA wild type DBS0305613 rccA- rccA increased resistance to cheating during development DBS0236880 rckA- rckA increased mound size | precocious aggregation | delayed slug development | delayed prestalk gene expression | delayed prespore gene expression | increased chemotaxis rate DBS0236885 rckA-/[act15]:myc:rckA rckA delayed development | decreased chemotaxis rate DBS0236881 rckA-/[act15]:myc:rckA(C551A) rckA delayed slug development | decreased chemotaxis rate DBS0236882 rckA-/[act15]:myc:rckA(E510G) rckA wild type | decreased chemotaxis rate DBS0236883 rckA-/[act15]:myc:rckA(E510G/N511A) rckA delayed slug development | decreased chemotaxis rate DBS0236884 rckA-/[act15]:myc:rckA(K867A) rckA development arrests at mound stage | decreased chemotaxis rate FR17 rdeA- rdeA precocious aggregation | decreased mound size | aberrant fruiting body morphogenesis | precocious development | precocious gene expression HH201 rdeA- rdeA aberrant chemotaxis to cAMP | increased cAMP level WTC10 rdeA- rdeA aberrant chemotaxis to cAMP | increased cAMP level | decreased macropinocytosis FR17 rdeA- rdeA precocious aggregation | decreased mound size | aberrant fruiting body morphogenesis | precocious development | precocious gene expression DBS0236886 rdeA-/[act15]:rdeA rdeA wild type DBS0350688 rdeA-/acaA- acaA | rdeA increased cAMP level | decreased sporulation DBS0350468 rdiA- rdiA decreased pinocytosis | decreased protein localization to cell cortex | decreased protein level | decreased actin filament polymerization | aberrant contractile vacuole morphology | decreased growth rate | aberrant cytokinesis DBS0351504 rdiA- rdiA aberrant cytokinesis DBS0236887 recA- recA decreased resistance to hydrogen peroxide | aberrant response to UV | decreased resistance to mitomycin C DBS0266664 redA- redA development arrests at mound stage | aberrant mound color DBS0350511 redA- redA decreased defense response to Gram-negative bacterium DG1047 redA- redA development arrests at mound stage | aberrant mound color DBS0236889 regA- regA increased resistance to cisplatin | aberrant chemotaxis to cAMP | increased cAMP level | aberrant fruiting body morphogenesis DBS0236958 regA- regA decreased spore germination | precocious sporulation | abolished protein localization to cell cortex | increased lateral pseudopodium formation | aberrant chemotaxis to cAMP HM332 regA- regA decreased lateral pseudopodium retraction HR45 regA- regA aberrant fruiting body morphogenesis HM1015 regA- regA increased cAMP level | decreased macropinocytosis | aberrant oscillatory cAMP signaling DBS0350372 regA-/KAX3 regA precocious sporulation | increased sporulation DBS0235706 regA-/[act15]:dhkK(D1125N) dhkK | regA aberrant fruiting body morphogenesis | precocious development DBS0235708 regA-/[act15]:dhkK(H825Q) dhkK | regA aberrant fruiting body morphogenesis | precocious development DBS0351475 regA-/[act15]:erkA erkA | regA delayed slug development DBS0351472 regA-/[act15]:regA(R588A,R589A,L594A,I595A,L596A) regA delayed development DBS0351284 regA-/[act15]:regA(S142A) regA aberrant fruiting body morphogenesis | precocious development DBS0351283 regA-/[act15]:regA(S142E) regA delayed development DBS0351285 regA-/[act15]:regA(S413A) regA increased mound size | delayed development DBS0351286 regA-/[act15]:regA(S413E) regA increased mound size | delayed development DBS0351287 regA-/[act15]:regA(T676A) regA delayed sporulation DBS0351288 regA-/[act15]:regA(T676E) regA aberrant fruiting body morphogenesis | precocious development DBS0350689 regA-/[regA]:regA regA wild type DBS0350670 regA-/[regA]:regA(D212N) regA precocious sporulation DBS0350380 regA-/dhkD- dhkD | regA aberrant fruiting body morphogenesis DBS0351473 regA-/regA(R588A,R589A,L594A,I595A,L596) regA precocious sporulation | decreased mound size | increased protein binding | aberrant fruiting body morphogenesis DBS0236891 regA-/tagB- regA | tagB decreased sporulation DBS0236892 regA-/tagC- regA | tagC decreased sporulation DBS0266818 repB(1-754) repB aberrant response to UV HM1351 rev3- rev3 aberrant vegetative growth | decreased resistance to cisplatin HM1451 rev3-/xpf- rev3 | xpf decreased resistance to cisplatin DBS0236893 rgaA- rgaA abolished cell migration to prestalk region | aberrant cytokinesis | abolished stalk cell differentiation | decreased protein kinase activation | abolished culmination | decreased sporulation DBS0349935 rgaA- rgaA aberrant stalk morphogenesis | increased number of tip-organizers | aberrant cellular response to fluid shear stress | increased actin filament polymerization | increased growth rate | increased cell motility | aberrant actin filament organization DBS0350398 rgaA- rgaA increased lateral pseudopodium formation | decreased myosin II assembly | increased chemotaxis rate DBS0349921 rgaA-/[act15]:GFP-mhcA rgaA aberrant stalk morphogenesis | aberrant development of tipped mound | abolished protein localization to apical plasma membrane DBS0349937 rgaA-/ctxA- ctxA | rgaA aberrant cytokinesis | abolished protein localization to cleavage furrow DBS0349936 rgaA-/gapA- gapA | rgaA aberrant cellular response to fluid shear stress | aberrant cytokinesis | abolished protein localization to cleavage furrow | increased cell motility DBS0350401 rgaA-/gapA- gapA | rgaA decreased protein localization to cleavage furrow | increased myosin II assembly | aberrant mitotic spindle organization | increased actin filament polymerization | decreased chemotaxis to cAMP | increased protein kinase activation DBS0350406 rgaA-/gapA-/[unk]:myc:gapA(R308E/K317E) gapA | rgaA increased protein kinase activation DBS0350402 rgaA-/iqgC- iqgC | rgaA decreased myosin II assembly | increased protein kinase activation DBS0351526 rgbA-/AX2 rgbA aberrant macropinocytosis | aberrant activation of GTPase activity | decreased macropinocytosis | aberrant engulfment during phagocytosis | decreased chemotaxis to folate DBS0351527 rgbA-/DdB rgbA aberrant macropinocytosis | increased activation of GTPase activity DBS0350019 rgfA- rgfA wild type DBS0350020 rgfA-/[act15]:rgfA rgfA decreased chemotaxis to folate | delayed development DBS0350108 rheb- rheb increased phagocytosis DBS0236894 rhgA- rhgA wild type DBS0350192 ric8- ric8 abolished gene expression | abolished chemotaxis to folate | decreased chemotaxis to cAMP | abolished aggregation | aberrant signal transduction DBS0350193 ric8-/[act15]:GFP:ric8 ric8 wild type DBS0236900 ripA- ripA decreased guanylyl cyclase activity | abolished activation of adenylate cyclase activity | decreased chemotaxis rate | decreased taxis | abolished aggregation | decreased establishment of cell polarity | aberrant regulation of protein kinase activity | decreased myosin II assembly | increased phagocytosis DBS0350770 ripA-/[act15]:GFP:rapA(G12V) rapA | ripA decreased protein kinase activation DBS0350115 ripA-/[act15]:GFP:rheb(Q64L) rheb | ripA increased phagocytosis DBS0236902 ripA-/[unk]:ripA(K680E/R681E) ripA aberrant sorocarp development | decreased chemotaxis rate DBS0236901 ripA-/[unk]ripA ripA wild type DBS0351068 rnf113- rnf113 delayed aggregation | increased cell-substrate adhesion | decreased cell motility DBS0351042 rnlA- rnlA decreased thermotaxis | decreased growth rate | decreased defense response to bacterium | decreased phototaxis DBS0236903 rnpA- rnpA increased gene expression DBS0350096 roco11- roco11 increased stalk length DBS0350095 roco4- roco4 delayed slug development | aberrant stalk development | delayed culmination DBS0350100 roco4-/[unk]:roco4(1018-1292(G1179S)) roco4 increased catalytic activity DBS0350098 roco4-/[unk]:roco4(1018-1292(S1187A)) roco4 abolished catalytic activity DBS0350099 roco4-/[unk]:roco4(1018-1292(S1189A)) roco4 decreased catalytic activity DBS0238225 rpkA- rpkA development arrests at loose mound stage | decreased defense response to Gram-negative bacterium | aberrant cellular response to nitrogen starvation | decreased phagocytosis | decreased cell motility | decreased establishment of cell polarity | abolished aggregation | aberrant cellular response to extracellular stimulus DBS0236906 rrpA- rrpA abolished post-transciptional gene silencing by RNA DBS0350178 rrpA-/rrpB-/rrpC- rrpA | rrpB | rrpC increased gene expression | decreased gene expression DBS0350189 rrpA-/rrpB-/rrpC-/[act6]:lacZ/[RNAi]lacZ rrpA | rrpB | rrpC abolished transitive RNA interference DBS0350176 rrpA-/rrpC- rrpA | rrpC increased gene expression | decreased gene expression DBS0350187 rrpA-/rrpC-/[act6]:lacZ/[AS]lacZ rrpA | rrpC aberrant production of siRNA involved in RNA interference DBS0350182 rrpA-/rrpC-/[act6]:lacZ/[RNAi]lacZ rrpA | rrpC abolished transitive RNA interference DBS0350177 rrpB-/rrpC- rrpB | rrpC increased gene expression | decreased gene expression DBS0350185 rrpB-/rrpC-/[act6]:lacZ/[AS]lacZ rrpB | rrpC aberrant production of siRNA involved in RNA interference DBS0350184 rrpB-/rrpC-/[act6]:lacZ/[RNAi]lacZ rrpB | rrpC abolished transitive RNA interference DBS0350209 rrpC- rrpC decreased gene expression | increased gene expression DBS0350219 rrpC-/[act15]:pre-miRNA rrpC increased pre-miRNA processing DBS0350216 rrpC-/[act6]:LacZ/[RNAi]lacZ rrpC abolished transitive RNA interference DBS0350217 rrpC-/[act6]:lacZ/[AS]lacZ rrpC aberrant production of siRNA involved in RNA interference DBS0236875 rtoA- rtoA decreased rate of endocytosis | increased defense response to Gram-negative bacterium | increased prestalk cell differentiation | delayed culmination DBS0236911 rtoA- rtoA delayed development DBS0236914 rzpA- rzpA aberrant aggregation | decreased slug migration | increased mound size | increased prespore gene expression | decreased prestalk gene expression | delayed development DBS0309040 sadA- sadA abolished protein localization to cell surface | decreased phagocytosis | decreased protein stabilization DBS0236921 sadA- sadA abolished cell-substrate adhesion | decreased phagocytosis | aberrant cytokinesis | increased growth rate | aberrant actin filament organization | aberrant cell morphology DBS0350974 sadA-/[act15]:gpaH gpaH | sadA aberrant cytokinesis DBS0349790 sadA-/[act15]:sadA(1-923):GFP sadA decreased cell-substrate adhesion DBS0349792 sadA-/[act15]:sadA(S924A/S925A):GFP sadA wild type DBS0349791 sadA-/[act15]:sadA(S924E/S925E):GFP sadA decreased cell-substrate adhesion DBS0236922 sadA-/[act15]:sadA:GFP sadA wild type DBS0351564 sbdS(1-30,TS18,31-274) sbds development arrests at loose mound stage | aberrant cellular process | abolished vegetative growth DBS0351566 sbdS(1-30,TS18,31-274)/[act15]:eIF(T56K) eIF6 | sbds wild type DG1105 scaA- scaA abolished aggregation DBS0350825 scaA- scaA decreased actin filament polymerization | aberrant chemotaxis to cAMP | abolished activation of GTPase activity | decreased protein kinase activation | abolished aggregation DBS0236924 scrA- scrA increased number of tip-organizers | abolished protein localization to endolysosome | decreased exocytosis | decreased pinocytosis | decreased actin filament polymerization | increased lateral pseudopodium formation | decreased phagocytosis | decreased vegetative cell size | decreased fruiting body size | precocious development IR46 scrA- scrA aberrant mitotic spindle organization | aberrant cytokinesis | abolished activation of GTPase activity | decreased vegetative cell size | decreased cell motility | aberrant cellular response to stress | aberrant pseudopodium formation | increased bleb assembly | abolished positive regulation of chemorepellant activity IR48 scrA- scrA decreased growth rate | aberrant cytokinesis | decreased bleb assembly | decreased phototaxis DBS0236925 scrA- scrA increased filopodium formation | decreased protein level | aberrant macropinocytosis | aberrant cytokinesis | decreased macropinocytosis | decreased cell motility | aberrant actin filament organization | aberrant pseudopodium formation DBS0351524 scrA-/[act15]:scrA(R177A,R179A,K180A,R183A,R184A,R187A,K190A,K191A,K194A) scrA decreased bleb assembly | increased cellular localization | aberrant pseudopodium formation DBS0351611 scrA-/[act15]:scrA(S287,290,301,335,339,384,388,389,430,432,433,437,440A) scrA aberrant pseudopodium formation DBS0351522 scrA-/[act15]:scrA(S430A,S432A,S433A,S437A,S440A) scrA decreased bleb assembly | increased cellular localization | aberrant pseudopodium formation DBS0351523 scrA-/[act15]:scrA(S430D,S432D,S433D,S437D,S440D) scrA decreased pseudopodium size DBS0349927 scrA-/[act15]:wasA:GFP/[ act8]:RFP:arcD scrA decreased establishment of cell polarity | decreased pseudopodium formation DBS0350063 scrA-/[tet]:scrA/mhcA- mhcA | scrA aberrant cytokinesis DBS0351610 scrA-/[tet]:scrA/wasA- scrA | wasA aberrant cell motility | abolished vegetative growth | abolished bleb assembly | aberrant pseudopodium formation DBS0238440 scrA-/[unk]:scrA(97-443):GFP scrA aberrant cytokinesis | increased vegetative cell size | decreased chemotaxis to cAMP | aberrant cytoskeleton organization DBS0238446 scrA-/[unk]:scrA:GFP scrA wild type SB18 scrA-/napA- napA | scrA decreased actin filament polymerization | decreased cell motility SB7 scrA-/pirA- pirA | scrA decreased vegetative cell size HM1163 sec1-/sec1(M213K/E258G/M427V/K527I/T541N/F558S/N581D) sec1 abolished cell motility HM1325 sec1-/sec1(M250L/A296V/M427L/S435R/K505N/V552D/H570Q) sec1 abolished cytokinesis | aberrant hypotonic response | abolished cell motility | aberrant plasma membrane organization | aberrant cell morphology DBS0350286 sec1-/sec1(M250L/A296V/M427L/S435R/K505N/V552D/H570Q)/gppA:GFP gppA | sec1 abolished contractile vacuole discharge DBS0350101 sec7- sec7 aberrant cell motility | decreased phagocytosis | decreased growth rate | aberrant phototaxis | decreased protein secretion DBS0306234 secG- secG decreased cell-substrate adhesion | decreased chemotaxis rate DBS0351035 seiP- seiP aberrant lipid droplet formation DBS0350264 sepA- sepA aberrant cytokinesis | delayed aggregation | decreased growth rate | decreased fruiting body size DBS0351077 sepA- sepA aberrant gene expression | increased cell-substrate adhesion | decreased cell motility DBS0350906 sepA- sepA decreased protein phosphorylation | aberrant pseudopodium formation DBS0351252 sesn- sesn increased mound size | aberrant standing slug morphology | decreased gene expression | decreased autophagy | aberrant response to oxidative stress DBS0236928 set1- set1 precocious aggregation | abolished histone H3-K4 methylation | precocious gene expression HG1132 sevA- sevA wild type DG1008 sfbA- sfbA decreased fruiting body size DBS0350889 sgcA-/AX2 sgcA aberrant aggregation | decreased guanylyl cyclase activity | aberrant chemotaxis to cAMP DBS0350888 sgcA-/AX3 sgcA aberrant aggregation | decreased guanylyl cyclase activity | aberrant chemotaxis to cAMP SA576 sgkA- sgkA decreased resistance to carboplatin | decreased growth rate | decreased resistance to cisplatin HM1093 sgkA-/sgkB- sgkA | sgkB decreased resistance to carboplatin | decreased growth rate | decreased resistance to cisplatin HM1091 sgkB- sgkB decreased resistance to carboplatin | decreased growth rate | decreased resistance to cisplatin SA555 sglA- sglA increased stalk width | increased resistance to cisplatin | increased mound size | decreased lateral pseudopodium retraction | decreased gene expression | abolished slug migration | decreased cell motility | decreased chemotaxis rate | decreased fruiting body size | aberrant cytoskeleton organization | decreased sporulation | increased resistance to carboplatin SA554 sglA- sglA delayed aggregation | decreased mound size DBS0236934 shkA- shkA aberrant aggregation | decreased phagocytosis | aberrant cytokinesis | decreased chemotaxis rate | decreased fruiting body size | decreased establishment of cell polarity | aberrant actin filament organization DBS0236935 sibA- sibA decreased cell-substrate adhesion | decreased phagocytosis DBS0302653 sibC- sibC decreased phagocytosis DBS0236936 sigB- sigB wild type DBS0236937 sigD- sigD wild type DBS0266513 sigN(group1)- sigN1 | sigN105-1 | sigN2 | sigN25 | sigN3 | sigN4 | sigN5 wild type DBS0266514 sigN(group2)- DDB_G0271820 | sigN10 | sigN11 | sigN12 | sigN14 | sigN6 | sigN7 | sigN8 | sigN9 wild type DBS0351170 sir2A- sir2A abolished slug migration | increased number of mound tips | increased gene expression | decreased gene expression | decreased growth rate | aberrant sorocarp development | decreased autophagy | decreased chemotaxis to cAMP | decreased cAMP level DBS0350859 sir2D- sir2D decreased gene expression | increased gene expression | increased number of mound tips | delayed aggregation | decreased growth rate | decreased autophagy | decreased mound size | decreased stalk length DBS0350860 sir2D-/[ecmAO]:lacZ sir2D decreased prestalk cell differentiation DBS0350861 sir2D-/[pspA]:lacZ sir2D aberrant prespore cell differentiation DBS0350985 slc4- slc4 aberrant transport DBS0349958 sma- sma increased chemotaxis to folate | decreased gene expression | increased cell-substrate adhesion | decreased vegetative cell size | increased cell-cell adhesion DBS0349957 sma-/ampA/[ampA]:ampA ampA | sma decreased chemotaxis to folate DBS0350327 smdA-/[pspA]:lacZ smdA aberrant gene expression DBS0236938 smkA- smkA aberrant cytokinesis | delayed development | decreased chemotaxis rate | decreased myosin II assembly HDB7YA smlA- smlA increased oscillatory cAMP signaling | decreased cell-cell adhesion | aberrant cellular metabolic process | decreased response to Gram-negative bacterium | increased resistance to cisplatin | decreased protein level | decreased guanylyl cyclase activity | increased myosin II assembly | increased actin filament polymerization | decreased cGMP-mediated signaling | decreased mound size | increased protein level | decreased secretion of lysosomal enzymes | increased cell motility | decreased fruiting body size DBS0302657 smlA-/cnrN- cnrN | smlA decreased fruiting body size DBS0236940 smlA-/ctnA- ctnA | smlA increased cell-cell adhesion DBS0304496 smlA-/sslA1(CR11) smlA | sslA1 increased fruiting body size DBS0350977 snfA- snfA decreased pinocytosis | increased cell death | decreased autophagic cell death | decreased phagocytosis | decreased number of autophagosomes | aberrant sorocarp development | decreased prespore cell differentiation | aberrant gene expression | aberrant protein modification | increased growth rate | aberrant prestalk cell differentiation | aberrant sporulation DBS0302523 sodC- sodC aberrant cytokinesis DBS0302524 sodC- sodC aberrant aggregation | decreased positive regulation of GTPase activity | decreased actin filament polymerization | increased actin filament polymerization | aberrant chemotaxis to cAMP | increased protein localization to plasma membrane | decreased chemotaxis rate | aberrant regulation of GTPase activity | aberrant protein localization to plasma membrane | aberrant cell morphology | increased protein kinase activation DBS0351063 sodC-/[unk]:rasG(C118A) rasG | sodC aberrant regulation of GTPase activity DBS0350894 sodD- sodD aberrant response to UV DBS0351196 sogA- sogA aberrant chemotaxis to cAMP | increased activation of GTPase activity DBS0350966 spaA- spaA abolished sporulation AK1346 spc3- spc3 decreased response to Gram-negative bacterium DBS0350891 spdA- spdA decreased substrate adhesion-dependent cell spreading | decreased phagocytosis DBS0350892 spdA-ins spdA decreased growth rate | increased substrate adhesion-dependent cell spreading | increased phagocytosis HL351 spiA- spiA decreased spore germination DBS0236943 spkA-1-/spkA-2- spkA-1 | spkA-2 decreased cell-substrate adhesion | aberrant cytokinesis | decreased mound size | decreased chemotaxis rate | decreased establishment of cell polarity | aberrant cell morphology | decreased fruiting body size DBS0236944 spkA-1-/spkA-2-/[act15]:spkA:FLAG spkA-1 | spkA-2 aberrant aggregation | decreased chemotaxis rate | aberrant actin filament organization | decreased establishment of cell polarity DBS0236945 splA- splA abolished sporulation | aberrant spore morphology | increased sorus size | aberrant sorus color | decreased stalk length DBS0350131 splB- splB abolished protein tyrosine phosphorylation | abolished protein localization to nucleus | abolished response to DIF-1 | decreased gene expression DBS0350582 splB-/pyk3- pyk3 | splB abolished gene expression | abolished protein localization to nucleus | aberrant sorocarp development | abolished protein phosphorylation DBS0236947 spnA- spnA abolished prespore cell differentiation | development arrests at mound stage | abolished prestalk cell differentiation | aberrant sorocarp development DBS0236948 spnA-/arkA- arkA | spnA decreased gene expression | increased sorus size | decreased stalk length | delayed gene expression DBS0236949 spr- spr decreased spore germination | decreased pteridine level | decreased cytochrome C oxidase activity | decreased growth rate DBS0350914 spsA- spsA decreased stalk length DBS0351174 srcp1- srcp1 aberrant protein modification DBS0236950 srfA(1-8):lacZ srfA decreased slug migration | aberrant fruiting body morphogenesis | delayed culmination DBS0236951 srfA- srfA aberrant spore morphology | decreased spore germination | aberrant spore coat morphology | decreased gene expression DBS0266691 srfB- srfB abolished stream development | aberrant extracellular cAMP signaling pathway | increased lateral pseudopodium formation | precocious aggregation | decreased growth rate | increased pinocytosis | aberrant cytokinesis | precocious gene expression DBS0304409 srsA- srsA increased mound size | decreased gene expression | increased gene expression | delayed aggregation DBS0304497 sslA1-/sslA1(CR11) sslA1 increased fruiting body size | decreased oscillatory cAMP signaling | decreased cGMP-mediated signaling DBS0236952 stkA- stkA decreased gene expression | increased prestalk gene expression | delayed prespore gene expression | aberrant fruiting body morphogenesis | increased prestalk cell differentiation HM1157 stlA- stlA aberrant aggregation | abolished sporulation | wild type | increased gene expression | decreased gene expression | aberrant stream morphology | decreased spore cell differentiation | decreased chemotaxis to cAMP | aberrant sorus color | abolished MPBD level | decreased cAMP level | aberrant sporulation DBS0350222 stlA-/[cotB]:lacZ stlA decreased sporulation | aberrant prespore cell differentiation DBS0350223 stlA-/stlB- stlA | stlB decreased gene expression | increased gene expression | aberrant gene expression | decreased stalk width DBS0350224 stlA-/stlB-/[ecmA]:lacZ stlA | stlB decreased prestalk cell differentiation HM1154 stlB- stlB abolished DIF-1 biosynthesis | abolished prestalk B cell differentiation | aberrant gene expression | aberrant fruiting body morphogenesis | decreased prestalk O cell differentiation | abolished lower cup formation | abolished outer basal disc formation | decreased prestalk cell differentiation DBS0351220 stlB- stlB abolished autophagosome organization | abolished autophagic cell death DBS0350409 stlB-/[act15]:stlB stlB wild type DBS0349941 sunB- sunB increased number of tip-organizers | aberrant cytokinesis DBS0304547 svkA- svkA delayed cell separation during cytokinesis | aberrant cytokinesis | aberrant fruiting body morphogenesis DBS0236055 swip- swip aberrant protein localization to cytoplasm | abolished exocytosis | abolished phagosome reneutralization | abolished actin filament polymerization | aberrant protein localization AK1321 swp1- swp1 decreased response to Gram-positive bacterium AK1200 tagA- tagA decreased spore cell differentiation | aberrant fruiting body morphogenesis AK859 tagA- tagA decreased spore germination | increased number of mound tips | decreased spore cell differentiation | increased prestalk A cell differentiation | delayed culmination | decreased sporulation AK1201 tagA-/[ecmA]:GFP tagA abolished cell migration to prestalk region AK228 tagB- tagB abolished sporulation | abolished DIF-1 biosynthesis | development arrests at mound stage | aberrant prestalk A cell differentiation DBS0350637 tagB-/[pkaC]:pkaC pkaC | tagB aberrant response to biotic stimulus | abolished spore cell differentiation DBS0350672 tagB-/pkaR- pkaR | tagB decreased sporulation DBS0236974 tagB-/psmA1- psmA1 | tagB abolished sporulation DBS0236975 tagC- tagC abolished sporulation | development arrests at mound stage DBS0350698 tagC-/[pkaC]:pkaC pkaC | tagC development arrests at mound stage | abolished spore cell differentiation DBS0236976 talA- talA decreased protein level | decreased cell-substrate adhesion | aberrant cytokinesis | decreased phagocytosis | aberrant cell morphology HG1666 talA- talA decreased cell-cell adhesion | decreased cell-substrate adhesion | aberrant cytokinesis | decreased growth rate | decreased phagocytosis | increased cell-substrate adhesion HG1663 talA- talA decreased cell-substrate adhesion HG1664 talA- talA decreased uropod retraction | decreased growth rate | decreased phagocytosis | aberrant mitotic actomyosin contractile ring contraction HG1665 talA- talA decreased cell-cell adhesion | aberrant cytokinesis DBS0304585 talA-/[act15]:FLAG:talB talA | talB decreased cell-substrate adhesion DBS0237616 talA-/[act15]:gbpD gbpD | talA increased cell-substrate adhesion | aberrant cell morphology | increased pseudopodium formation DBS0238395 talA-/[act15]:rapA(G12V) rapA | talA increased cell-substrate adhesion DBS0350442 talA-/sibA- sibA | talA wild type DBS0304581 talA-/talB- talA | talB development arrests at loose mound stage | abolished cell-substrate adhesion | aberrant cytokinesis | abolished cell motility | increased bleb assembly DBS0304582 talA-/talB-/[act15]:FLAG:talB talA | talB wild type DBS0350713 talA-/talB-/[act15]:talB(K16A) talA | talB decreased cell-substrate adhesion HKT104 talB- talB decreased slug migration | aberrant extracellular cAMP signaling pathway | aberrant cellular process | decreased cell motility | development arrests at tipped mound stage | increased protein level | aberrant signal transduction DBS0302472 talB- talB abolished autophagosome organization | abolished autophagic cell death | aberrant autophagic cell death DBS0304586 talB-/[act15]:talA:GFP talA | talB aberrant fruiting body morphogenesis DBS0350712 talB-/[act15]:talB(K16A) talB development arrests at tipped mound stage DBS0351501 talB-/pikB- pikB | talB aberrant cellular process DBS0351346 tert- tert increased gene expression | decreased gene expression | aberrant cell adhesion | aberrant chemotaxis to cAMP | aberrant sorocarp development | delayed development | aberrant oscillatory cAMP signaling | decreased cAMP level DBS0351559 tert- tert decreased catalytic activity | increased gene expression AK1505 tgrB1- tgrB1 development arrests at loose mound stage | delayed sporulation | decreased cell motility | decreased sporulation DBS0351148 tgrB1-/tgrB1(1-827):HA tgrB1 development arrests at mound stage AK1540 tgrB1-/tgrC1- tgrB1 | tgrC1 development arrests at loose mound stage | abolished cell-cell self recognition | aberrant oscillatory cAMP signaling AK1549 tgrB1-/tgrC1-/QS31|tgrB1/tgrC1 tgrB1 | tgrC1 wild type AK1552 tgrB1-/tgrC1-/QS38|tgrB1/tgrC1 tgrB1 | tgrC1 wild type AK1555 tgrB1-/tgrC1-/QS45|tgrB1/tgrC1 tgrB1 | tgrC1 wild type AK1546 tgrB1-/tgrC1-/QS4|tgrB1/tgrC1 tgrB1 | tgrC1 wild type AK1664 tgrB1-/tgrC1-/alg9(-19ins) alg9 | tgrB1 | tgrC1 decreased sporulation DBS0351131 tgrB1-/tgrC1-/tgrB1(G275D) tgrB1 | tgrC1 wild type DBS0351132 tgrB1-/tgrC1-/tgrB1(G307D) tgrB1 | tgrC1 wild type DBS0351133 tgrB1-/tgrC1-/tgrB1(L846F) tgrB1 | tgrC1 aberrant standing slug morphology | increased number of mound tips | decreased fruiting body size AK127 tgrC1- tgrC1 development arrests at loose mound stage | aberrant aggregation | abolished gene expression | increased mound size | decreased gene expression AK1521 tgrC1- tgrC1 abolished sporulation | development arrests at loose mound stage | decreased cell motility AK1657 tgrC1-/(QS38|tgrC1)/alg9(-19ins) alg9 | tgrC1 delayed development | decreased fruiting body size | decreased sporulation AK1661 tgrC1-/alg9(-19ins) alg9 | tgrC1 delayed development | decreased fruiting body size | decreased sporulation DBS0350743 tgrC1-/alg9(-19ins)-REMI alg9 | tgrC1 decreased sporulation DBS0350625 tgrC1-/stcA- stcA | tgrC1 decreased mound size | delayed development | decreased sporulation DBS0350626 tgrC1-/stcB- stcB | tgrC1 decreased mound size | delayed development | decreased sporulation DBS0350627 tgrC1-/stcC- stcC | tgrC1 aberrant stream morphology | delayed development | decreased fruiting body size | decreased sporulation AK244 tipA- tipA increased number of tip-organizers | increased mound size | development arrests at mound stage | decreased prestalk gene expression JS64 tipA-/tipB-/[act15]:lacZ tipA | tipB increased mound size | increased number of mound tips | development arrests at mound stage JS98 tipA-/tipC-/[ecmA]:lacZ tipA | tipC development arrests at loose mound stage JS128 tipA-/tipD-/[ecmA]:lacZ tipA | tipD development arrests at loose mound stage DBS0351500 tipB- tipB increased number of mound tips JS56 tipB- tipB increased number of tip-organizers | increased mound size | increased number of mound tips | development arrests at mound stage JS99 tipB-/tipC-/[ecmA]:lacZ tipB | tipC increased number of mound tips | development arrests at tipped mound stage JS129 tipB-/tipD-/[ecmA]:lacZ tipB | tipD increased number of mound tips | development arrests at tipped mound stage JS55 tipC- tipC increased number of tip-organizers | increased mound size | development arrests at mound stage | decreased number of autophagosomes | decreased autophagy DBS0350729 tipC-/[unk]:tipC(2725-3848):GFP tipC decreased fruiting body size JS130 tipC-/tipD-/[ecmA]:lacZ tipC | tipD development arrests at loose mound stage JS93 tipD- tipD increased number of tip-organizers | increased mound size | development arrests at mound stage | aberrant vacuole organization | decreased autophagy DBS0350730 tipD- tipD decreased pinocytosis | increased cell death | decreased spore germination | decreased catalytic activity | increased gene expression | increased number of mound tips | increased protein modification | aberrant phagosome maturation | aberrant slug development | aberrant fruiting body morphogenesis | abolished protein localization to autophagosome DBS0304519 tirA- tirA decreased response to Gram-negative bacterium | decreased defense response to Gram-negative bacterium | aberrant defense response to bacterium | decreased growth rate | aberrant phagocytosis | aberrant vegetative growth YLD31A tlp2- tlp2 decreased growth rate DBS0236016 tmcB-/V12 tmcB decreased macrocyst size | aberrant macrocyst formation DBS0236018 tmcC-/V12 tmcC aberrant macrocyst formation DBS0351084 tnlA/tnlB-REMI tnlA | tnlB decreased gene expression | delayed aggregation | increased cell-substrate adhesion | decreased cell motility | increased protein kinase activation DBS0350285 tom1- tom1 decreased rate of endocytosis DBS0237017 torA- torA delayed aggregation | decreased growth rate | decreased cell motility | decreased chemotaxis rate DBS0237018 torA-/[act15]:torA:GFP torA abolished vegetative growth DBS0351498 tpc2- tpc2 increased number of autophagosomes | increased gene expression | decreased gene expression | aberrant vegetative growth | aberrant calcium-mediated signaling | increased protein kinase activity | delayed development | increased lysosomal pH DBS0350506 tpp1- tpp1 aberrant response to chemical DBS0350504 tpp1- tpp1 increased autophagic cell death | decreased catalytic activity | aberrant response to chemical | aberrant cell morphology | precocious development | decreased sporulation DBS0350505 tpp1-/[cotB]:tpp1 tpp1 wild type DBS0350507 tpp1-/stpA- stpA | tpp1 wild type DBS0351017 tpp1F- tpp1F wild type DBS0351558 tpt1- tpt1 decreased spore germination | decreased gene expression | decreased growth rate | aberrant cytokinesis | decreased number of mounds | decreased macropinocytosis | delayed development | aberrant fruiting body morphogenesis | increased prestalk cell differentiation DBS0351265 trfA- trfA aberrant aggregation | aberrant vegetative growth | decreased chemotaxis to cAMP DBS0237924 triA- triA decreased cell-cell adhesion | increased stalk width | increased number of mounds | decreased spore germination | aberrant upper cup formation | aberrant cell motility | aberrant stream morphology | decreased spore size | decreased cell fate determination | aberrant late culminant morphology DBS0237996 triA- triA aberrant late culminant morphology DBS0237997 triA- triA aberrant late culminant morphology DBS0237998 triA-/[act15]:GFP triA aberrant late culminant morphology DBS0237999 triA-/[ecmAO]:lacZ:[ecmAO]:gus triA increased prestalk O cell differentiation DBS0238001 triA-/[psA]:lacZ:[psA]:gus triA increased prespore cell differentiation DBS0351605 trm9- trm9 decreased protein level DBS0350107 tsc2- tsc2 decreased phagocytosis DBS0237022 tsg101- tsg101 decreased fruiting body size DBS0351612 tsg101- tsg101 aberrant cellular process | decreased protein localization | increased defense response to Gram-positive bacterium DBS0350816 tspC- tspC aberrant response to osmotic stress HM1725 tstD- tstD decreased growth rate | decreased plasma membrane organization | increased growth rate DBS0302370 tsuA- tsuA increased oscillatory cAMP signaling | abolished establishment of cell polarity | aberrant chemotaxis to folate | aberrant chemotaxis to cAMP | delayed aggregation | decreased mound size | decreased fruiting body size | aberrant pseudopodium formation DBS0302383 tsuA-/[unk]:tsuA(1-1774):YFP tsuA abolished protein localization to microtubules | abolished protein localization to microtubule organizing center | decreased mound size | decreased fruiting body size DBS0302385 tsuA-/[unk]:tsuA(1-260):YFP tsuA abolished protein localization to microtubules | abolished protein localization to microtubule organizing center | decreased mound size | decreased fruiting body size DBS0302384 tsuA-/[unk]:tsuA(1774-2247):YFP tsuA abolished protein localization to microtubules | abolished protein localization to microtubule organizing center | decreased mound size | decreased fruiting body size DBS0302382 tsuA-/[unk]:tsuA(K34R):YFP tsuA decreased mound size | decreased fruiting body size DBS0302381 tsuA-/[unk]:tsuA:YFP tsuA wild type DBS0237024 ubcB- ubcB increased number of tip-organizers | development arrests at mound stage DBS0306165 ube2t- ube2t decreased resistance to cisplatin DBS0237025 ubpA- ubpA decreased gene expression | decreased chemotaxis rate | abolished aggregation DBS0237026 ubpB- ubpB aberrant sorus morphology | increased prestalk gene expression | decreased prespore gene expression | precocious development DBS0351464 uduB-/AX3 uduB increased prestalk cell differentiation DBS0237027 ufc1- ufc1 wild type DBS0237028 ugpB-/DH1 ugpB abolished sporulation | decreased glycogen level | aberrant cell differentiation | decreased fruiting body size | delayed culmination DBS0266763 ugpB-/DH1 ugpB decreased stalk length DBS0266764 ugpB-/HMX ugpB abolished cellulose biosynthesis | decreased autophagic vacuole organization | aberrant cell morphology DBS0350591 uppA- uppA decreased catalytic activity DBS0237031 vacA- vacA wild type DBS0351567 vacA- vacA decreased phagocytosis DBS0351571 vacA-/vacB-/vacC- vacA | vacB | vacC decreased cell-substrate adhesion | decreased gene expression | decreased phagocytosis | aberrant phagosome maturation | decreased protein localization | aberrant protein localization DBS0237032 vacB- vacB decreased exocytosis | increased defense response to bacterium DBS0351568 vacB- vacB decreased phagocytosis DBS0351570 vacB-/vacC- vacB | vacC decreased phagocytosis DBS0351569 vacC- vacC decreased phagocytosis DBS0237034 vasP- vasP abolished filopodium formation DBS0237035 vasP- vasP decreased lateral pseudopodium retraction | decreased cell-substrate adhesion | decreased vegetative cell size | decreased cell motility | decreased chemotaxis rate | aberrant hyperosmotic response | aberrant actin filament organization | decreased chemotaxis to cAMP | abolished filopodium formation | decreased filopodium formation DBS0237033 vasP-/[act15]:GFP:vasP(1-264/285-380) vasP abolished filopodium formation DBS0237836 vasP-/[act15]:YFP:wipA vasP | wipA decreased filopodium formation DBS0237842 vasP-/[act15]:YFP:wipA/[act15]:vasP:FLAG vasP | wipA increased filopodium formation DBS0351313 vasP-/[act15]:abpB(129-295) abpB | vasP aberrant cellular process DBS0351300 vasP-/[act15]:eYFP:vasP(S141A) vasP decreased protein localization to cell cortex | wild type | decreased lateral pseudopodium retraction | decreased establishment of cell polarity | aberrant actin filament organization DBS0351301 vasP-/[act15]:eYFP:vasP(S141D) vasP aberrant hyperosmotic response | decreased filopodium formation DBS0237036 vasP-/[act15]:myr:vasP vasP increased filopodium formation | aberrant cytokinesis | increased actin filament polymerization DBS0237040 vasP-/[act15]:vasP vasP decreased filopodium formation DBS0237840 vasP-/[act15]:vasP vasP increased filopodium formation | increased actin filament polymerization DBS0237037 vasP-/[act15]:vasP(1-110:231-380) vasP aberrant cytokinesis | increased actin filament polymerization | decreased filopodium formation DBS0237038 vasP-/[act15]:vasP(1-228) vasP decreased filopodium formation DBS0237039 vasP-/[act15]:vasP(111-380) vasP increased filopodium formation | increased actin filament polymerization DBS0350466 vasP-/[unk]:vasP(1-197:221-380) vasP wild type DBS0350467 vasP-/[unk]:vasP(1-261:285-380) vasP decreased cell motility | abolished filopodium formation DBS0351536 vasP-/hspc300- hspc300 | vasP development arrests at slug stage | aberrant sorocarp development DBS0351537 vasP-/pirA- pirA | vasP increased number of mound tips DBS0350602 vilA- vilA decreased chemotaxis to cAMP | decreased phototaxis DBS0236058 vmp1- vmp1 aberrant aggregation | decreased exocytosis | increased cell death | aberrant autophagy | decreased gene expression | decreased growth rate | aberrant hypotonic response | decreased macropinocytosis | aberrant vacuole organization | aberrant protein localization to autophagosome | aberrant protein localization | aberrant signal transduction DBS0351250 vmp1-/[act15]:vmp1(G268L):GFP vmp1 aberrant aggregation | aberrant protein localization to autophagosome DBS0350873 vps13F- vps13F aberrant defense response to bacterium | decreased growth rate DG1118 vps46- vps46 increased sorus size DBS0237046 vwkA- vwkA increased myosin II assembly | decreased growth rate | aberrant cytokinesis | aberrant contractile vacuole morphology | aberrant hypotonic response | delayed development | increased protein level | aberrant fruiting body morphogenesis | decreased contractile vacuole discharge DBS0350290 vwkA-/[act15]:GFP:mhcA mhcA | vwkA aberrant myosin II filament organization TL61 wacA- wacA wild type TL99 wacA- wacA wild type DBS0237048 warA- warA development arrests at slug stage | increased basal disc size | decreased prespore cell differentiation | increased prestalk O cell differentiation DBS0237049 warA- warA development arrests at slug stage | increased basal disc size | decreased prespore cell differentiation | increased prestalk O cell differentiation DBS0237050 warA-/hbx2- hbx2 | warA increased basal disc size | development arrests at mound stage | decreased prespore cell differentiation | increased prestalk O cell differentiation DBS0351506 wasA- wasA aberrant protein localization to trailing edge DBS0351509 wasA-/[tet]:scrA/[unk]:GFP:wasA(I173A/F179A) scrA | wasA aberrant pseudopodium formation DBS0351508 wasA-/[unk]:GFP:wasA(I173A/F179A) wasA aberrant protein localization to trailing edge | decreased establishment of cell polarity DBS0237051 wasA1- wasA decreased cell motility | delayed development | aberrant actin filament organization DBS0237052 wasA1-/[tet]:YFP:wasA2 wasA decreased actin filament polymerization | abolished positive chemotaxis | abolished aggregation | aberrant actin filament organization DBS0237812 wasA1-/[tet]:YFP:wasA2/[act15]:wasA wasA increased actin filament polymerization at leading edge DBS0237811 wasA1-/[tet]:YFP:wasA2/[act15]:wasA(Y33A/W39A/F90A/F91A) wasA decreased actin filament polymerization | decreased actin filament polymerization at leading edge DBS0237820 wasA1-/[tet]:YFP:wasA2/[act15]:wipA wasA | wipA abolished positive chemotaxis DBS0350254 wasB- wasB abolished protein localization to cytoplasmic vesicle | aberrant chemotaxis to cAMP | increased actin filament polymerization | increased protein level | aberrant pseudopodium formation DBS0350255 wasB-/[act15]:YFP:wasB wasB wild type DBS0351525 wasC- wasC increased actin filament polymerization | decreased phagocytosis | increased cell-substrate adhesion | decreased chemotaxis rate DBS0350239 washc5- washc5 abolished exocytosis | decreased protein level | decreased growth rate | decreased phagocytosis | aberrant endosome morphology | decreased vegetative cell size | abolished phagosome reneutralization | decreased secretion of lysosomal enzymes | abolished actin filament polymerization | aberrant lysosome organization DBS0351185 washc5-/[act15]:washc5(N457D):GFP washc5 abolished exocytosis DG1053 wimA- wimA aberrant fruiting body morphogenesis DG1064 wimA- wimA aberrant fruiting body morphogenesis DBS0349863 wshA- wshA increased protein localization | abolished exocytosis | decreased defense response to Gram-negative bacterium | decreased macroautophagy | abolished endocytic recycling | aberrant vegetative growth | decreased phagocytosis | decreased protein processing in phagocytic vesicle | aberrant phagosome maturation | abolished phagosome reneutralization | decreased secretion of lysosomal enzymes | increased defense response to Gram-positive bacterium | decreased protein localization | aberrant lysosome organization | aberrant protein localization DBS0350872 wshA-/[act15]:GFP:wshA/[act15]:vatB:RFP vatB | wshA abolished endocytic recycling DBS0350451 wshA-/atg1- atg1 | wshA wild type DBS0350248 wshA-/fam21-/[act15]:GFP:fam21 fam21 | wshA abolished actin filament polymerization DBS0350247 wshA-/fam21-/[act15]:GFP:wshA fam21 | wshA aberrant lysosome organization DBS0350943 xacA- xacA decreased hypotonic response | aberrant contractile vacuole morphology | aberrant actin filament organization DBS0350950 xacA- xacA increased lateral pseudopodium formation | decreased chemotaxis to cAMP | aberrant actin filament organization DBS0350944 xacA-/[act15]:xacA(1-320) xacA decreased growth rate | aberrant cytokinesis DBS0350945 xacA-/[act15]:xacA(779-1335) xacA decreased hypotonic response | aberrant contractile vacuole morphology HM1456 xpc- xpc wild type | aberrant vegetative growth HM1403 xpf- xpf aberrant vegetative growth | decreased resistance to cisplatin AK235 yakA- yakA abolished aggregation AK800 yakA- yakA decreased protein localization to cell cortex | decreased gene expression | aberrant cell cycle | increased cellular thermotolerance | aberrant gene expression | decreased protein kinase activation | abolished aggregation | aberrant response to oxidative stress | aberrant cellular response to stress | decreased cAMP level DBS0237087 yakA-/AX3 yakA decreased growth rate | abolished aggregation | abolished actin filament polymerization | decreased cGMP biosynthesis DBS0237091 yakA-/[crlA]:crlA crlA | yakA abolished vegetative growth DBS0350058 yakA-/keaA- keaA | yakA wild type DBS0351199 yakA-/pkaC- pkaC | yakA aberrant cellular response to stress AK804 yakA-/pufA- pufA | yakA increased protein kinase activity | increased protein level | aberrant fruiting body morphogenesis | increased growth rate | precocious development DBS0350898 yelA-/AX2 yelA precocious prestalk gene expression | increased basal disc size DG1014 yelA-/AX4 yelA aberrant spore morphology | precocious sporulation | development arrests at mound stage | aberrant mound color | aberrant sporulation DBS0349797 zak2- zak2 decreased prespore gene expression | decreased protein kinase activation | aberrant fruiting body morphogenesis | decreased sporulation DBS0349883 zak2-/[act15]:GFP zak2 decreased sporulation DBS0349798 zak2-/[ecmA]:LacZ zak2 aberrant prestalk gene expression DBS0349882 zak2-/[ecmA]:zakA zak2 | zakA precocious prestalk gene expression ARK100-110 zakA- zakA abolished stream development | decreased protein kinase activity | increased prestalk gene expression | decreased prespore gene expression | aberrant fruiting body morphogenesis | decreased chemotaxis to cAMP | delayed culmination | decreased sporulation DBS0238142 zakA- zakA development arrests at tipped mound stage DBS0349803 zakA-/[ecmB]:LacZ zakA aberrant prestalk gene expression DG1050 zipA- zipA decreased fruiting body size DBS0350068 zizB- zizB aberrant fruiting body morphogenesis | delayed development | decreased chemotaxis to cAMP