# NOTICE

This notice applies to **every asset in this MeDIC release**.

## Attribution

Contains data from the European Medicines Agency (© EMA), the Pharmaceuticals and Medical Devices Agency of Japan (PMDA, https://www.pmda.go.jp), the Central Drugs Standard Control Organisation of India (CDSCO), EveryCure (drug-list and disease-list, CC BY 4.0) and the Mondo Disease Ontology (CC BY 4.0). Data has been edited: source records were parsed, translated, normalised, and mapped to ontology identifiers by the MeDIC pipeline. None of these bodies endorses this derived work.

## Licence

- **This release as a whole:** https://creativecommons.org/licenses/by/4.0/
- **MeDIC's own mapping assertions:** offered as https://creativecommons.org/publicdomain/zero/1.0/
- **Full terms, per source:** https://github.com/monarch-initiative/medic/blob/main/LICENSING.md

MeDIC grants no rights over upstream source content. The original licence of each contributing source remains in force and must be respected; parsing, translation, normalisation and mapping to ontology identifiers do not alter it. Where terms conflict, the stricter governs.

## What is in this release, and whose data it contains

| Asset | Sources | Attribution |
|---|---|---|
| `products/drug_list.yaml` | the U.S. Food and Drug Administration (Orange Book), the U.S. Food and Drug Administration (Purple Book), the European Medicines Agency (© EMA), the Pharmaceuticals and Medical Devices Agency of Japan (PMDA, https://www.pmda.go.jp), the Russian State Register of Medicines (GRLS), the Central Drugs Standard Control Organisation of India (CDSCO), the China NMPA Center for Drug Evaluation, EveryCure (drug-list and disease-list, CC BY 4.0) | required |
| `products/disease_list.yaml` | the Mondo Disease Ontology (CC BY 4.0), EveryCure (drug-list and disease-list, CC BY 4.0) | required |
| `products/indication_list.yaml` | the U.S. National Library of Medicine (DailyMed), the European Medicines Agency (© EMA), the Pharmaceuticals and Medical Devices Agency of Japan (PMDA, https://www.pmda.go.jp), the Central Drugs Standard Control Organisation of India (CDSCO) | required |
| `products/contraindication_list.yaml` | the U.S. National Library of Medicine (DailyMed) | courtesy |
| `products/research_list.yaml` | PubMed | courtesy |
| `exports/drug_list_flexible.csv` | the U.S. Food and Drug Administration (Orange Book), the U.S. Food and Drug Administration (Purple Book), the European Medicines Agency (© EMA), the Pharmaceuticals and Medical Devices Agency of Japan (PMDA, https://www.pmda.go.jp), the Russian State Register of Medicines (GRLS), the Central Drugs Standard Control Organisation of India (CDSCO), the China NMPA Center for Drug Evaluation, EveryCure (drug-list and disease-list, CC BY 4.0) | required |
| `exports/drug_list_stringent.csv` | the U.S. Food and Drug Administration (Orange Book), the U.S. Food and Drug Administration (Purple Book), the European Medicines Agency (© EMA), the Pharmaceuticals and Medical Devices Agency of Japan (PMDA, https://www.pmda.go.jp), EveryCure (drug-list and disease-list, CC BY 4.0) | required |
| `exports/orangebook.xlsx` | the U.S. Food and Drug Administration (Orange Book) | courtesy |
| `exports/purplebook.xlsx` | the U.S. Food and Drug Administration (Purple Book) | courtesy |
| `exports/ema.xlsx` | the European Medicines Agency (© EMA) | required |
| `exports/pmda.xlsx` | the Pharmaceuticals and Medical Devices Agency of Japan (PMDA, https://www.pmda.go.jp) | required |
| `exports/russia.csv` | the Russian State Register of Medicines (GRLS) | courtesy |
| `exports/india.csv` | the Central Drugs Standard Control Organisation of India (CDSCO) | required |
| `exports/medic_nodes.jsonl` | the U.S. Food and Drug Administration (Orange Book), the U.S. Food and Drug Administration (Purple Book), the European Medicines Agency (© EMA), the Pharmaceuticals and Medical Devices Agency of Japan (PMDA, https://www.pmda.go.jp), the Russian State Register of Medicines (GRLS), the Central Drugs Standard Control Organisation of India (CDSCO), the China NMPA Center for Drug Evaluation, EveryCure (drug-list and disease-list, CC BY 4.0), the Mondo Disease Ontology (CC BY 4.0) | required |
| `exports/medic_edges.jsonl` | the U.S. National Library of Medicine (DailyMed), the European Medicines Agency (© EMA), the Pharmaceuticals and Medical Devices Agency of Japan (PMDA, https://www.pmda.go.jp), the Central Drugs Standard Control Organisation of India (CDSCO), PubMed | required |
| `exports/medic_kgx_metadata.yaml` | MeDIC | — |
| `exports/infores_medic.yaml` | MeDIC | — |
| `exports/medic_drug_mappings.sssom.tsv` | the U.S. Food and Drug Administration (Orange Book), the U.S. Food and Drug Administration (Purple Book), the European Medicines Agency (© EMA), the Pharmaceuticals and Medical Devices Agency of Japan (PMDA, https://www.pmda.go.jp), the Russian State Register of Medicines (GRLS), the Central Drugs Standard Control Organisation of India (CDSCO), the China NMPA Center for Drug Evaluation, EveryCure (drug-list and disease-list, CC BY 4.0) | required |
| `exports/medic_statements.tsv` | the U.S. National Library of Medicine (DailyMed), the European Medicines Agency (© EMA), the Pharmaceuticals and Medical Devices Agency of Japan (PMDA, https://www.pmda.go.jp), the Central Drugs Standard Control Organisation of India (CDSCO), the Russian State Register of Medicines (GRLS), the China NMPA Center for Drug Evaluation, PubMed | required |
| `exports/medic_reliable.tsv` | the U.S. National Library of Medicine (DailyMed), the European Medicines Agency (© EMA), the Pharmaceuticals and Medical Devices Agency of Japan (PMDA, https://www.pmda.go.jp), the Central Drugs Standard Control Organisation of India (CDSCO), the Russian State Register of Medicines (GRLS), the China NMPA Center for Drug Evaluation, PubMed | required |