Change to 1811_phenotype data ============================= The random walk matrix has been updated to use a more recent version of String (v 10), consequently the file name as changed. This will cause start-up errors when using exomiser-cli-11.0.0 or below with the 1811_phenotype data. To fix the error ending with this message: Factory method 'randomWalkMatrix' threw exception; nested exception is java.lang.IllegalStateException: Could not open file nio: /path/to/exomiser-data/1811_phenotype/rw_string_9_05.mv You will need to update the application.properties, changing this line: #exomiser.phenotype.random-walk-file-name=rw_string_9_05.gz to exomiser.phenotype.random-walk-file-name=rw_string_10.mv Sorry for any inconvenience, Team Exomiser.